UCHIUMI Toshio

Birthday

E-Mail

Research Careers (Niigata University)

1. Professor, Department of Biology, Faculty of Science (2003/10 - )
2. Research Associate, Faculty of Medicine (1981/06 - 1996/07)

Research Fields (Grant-in-Aid for Scientific Research)

1. Molecular biology
2. Functional biochemistry

Research Fields (ReaD)

1. Molecular genetics

Papers

1. "Identification of L: -3-hydroxykynurenine O-sulfate in the buccal gland secretion of the parasitic lamprey, Lethenteron japonicum", Odani S, Ito N, Hasegawa M, Uchiumi T, Hase S. , Amino Acids, Vol.43, No.6, pp.2505 - 2512(2012)
2. "Archaeal ribosomal stalk protein interacts with translation factors in a nucleotide-independent manner via its conserved C terminus", Nomura, N., Honda, T., Baba, K., Naganuma, T., Tanzawa, T., Arisaka, F., Noda, M., Uchiyama, S., Tanaka, I., Yao, M., and Uchiumi T., Proc. Natl. Acad. Sci. U S A, Vol.109, No.10, pp.3748 - 3753(2012)
3. "Analysis of Chimeric Ribosomal Stalk Complexes from Eukaryotic and Bacterial Sources: Structural Features Responsible for Specificity of Translation Factors", Mochizuki, M., Kitamyo, M., Miyoshi, T., Ito, K., and Toshio Uchiumi T., Genes to Cells, Vol.17, No.4, pp.273 - 284(2012)
4. "Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit", Muhs, M., Yamamoto, H., Ismer, J., Takaku, H., Nashimoto, M., Uchiumi, T., Nakashima, N., Mielke, T., Hildebrand, P. W., Nierhaus, K. H., and Spahn, C. M. , Nucleic Acid Res., Vol.39, No.12, pp.5264 - 5275(2011)
5. "Comparative proteomic analysis of the ribosomes in 5-fluorouracil resistance of a human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis", Kimura, K., Wada, A., Ueta, M., Ogata, A., Tanaka, S., Sakai, A., Yoshida, H., Fushitani, H., Miyamoto, A., Fukushima, M., Uchiumi, T., and Tanigawa, N. , Int. J. Oncol., Vol.37, No.5, pp.1271 - 1278(2010)
6. "Multiple gamma-glutamylation: a novel type of post-translational modification in a diapausing Artemia cyst protein", Hasegawa, M., Ikeda, Y., Kanzawa, H., Sakamoto, M., Goto, M., Tsunasawa, S., Uchiumi, T., Biochem. Biophys. Res. Commun., Vol.394, No.1, pp.36 - 41(2010)
7. "Structural basis for translation factor recruitment to the eukaryotic/archaeal ribosomes", Naganuma T, Nomura N, Yao M, Mochizuki M, Uchiumi T, Tanaka I. , J. Biol. Chem.(2010)
8. "Structural basis of novel interactions between the small-GTPase and GDI-like domains in prokaryotic FeoB iron transporter", Hattori M, Jin Y, Nishimasu H, Tanaka Y, Mochizuki M, Uchiumi T, Ishitani R, Ito K, Nureki O., Structure, Vol.17, No.10, pp.1345 - 1355(2009)
9. "Functional analysis of structural motifs in dicistroviruses", Nakashima N, Uchiumi T., Virus Res. , Vol.139, No.2, pp.137 - 147(2009)
10. "Engineering and characterization of the ribosomal L10.L12 stalk complex. A structural element responsible for high turnover of the elongation factor G-dependent GTPase", Miyoshi T, Nomura T, Uchiumi T., J. Biol. Chem. , Vol.284, No.1, pp.85 - 92(2009)

Total 27 [Show All]

Reviews

1. (The commerce magazine) "Nobel prize for the elucidation of ribosome structure and function", Toshio Uchiumi, Material Stage, Vol.9, No.10(Technical information institute Co. Ltd.), pp.1 - 3(2010)
2. (Academic Journal) "Ribosome Structure and Drug Design", Toshio Uchiumi, Gene&Medicine MOOK, Vol.4(MEDICAL DO CO.,LTD.), pp.181 - 188(2006)
3. (Academic Journal) "Ribosome Structure Revealed by X-ray crystallography", Toshio Uchiumi, Experimental Medicine, Vol.20, No.10(Yodosha), pp.1408 - 1414(2002)

Presentations

1. "Structural Basis of the Substrate Recognition Mechanisms of Peptidyl-tRNA Hydrolase from Escherichia coli", Kosuke Ito, Ryo Murakami, Hao Qi, Yoshihiro Shimizu, Kin-ichiro Miura, Takuya Ueda, Toshio Uchiumi, The 16th Annual Meeting of the RNA Society(2011)
2. "Introduction of a Lepidoptera-specific sequence within the GTPase-associated center of 28S rRNA into Escherichia coli 23S rRNA: Effects of the mutations", Ryo Maruyama, Kazuyuki Yusa, Masahiro Mochizuki, Kosuke Ito, Takaomi Nomura, Toshio Uchiumi, The 16th Annual Meeting of the RNA Society(2011)
3. "The stalk protein complex at the ribosomal GTPase-associated center", Toshio Uchiumi, Current Issues of Ribosomal Structur and Function (2010)