Faculty Profiles - OOISHI Makoto

Papers - OOISHI Makoto

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Non-sinus type of transverse sinus dural arteriovenous fistulas on the arachnoid granulation of the dural sinus wall. International journal

Tomoaki Suzuki, Hitoshi Hasegawa, Kouichirou Okamoto, Kohei Shibuya, Hidemoto Fujiwara, Makoto Oishi

Surgical neurology international 15 43 - 43 2024

Language：English

BACKGROUND: The etiology of a non-sinus-type dural arteriovenous fistulas (DAVFs) with shunt points located on the sinus wall, previously described as on-the-wall-type DAVFs, is unknown. CASE DESCRIPTION: Two cases of non-sinus-type transverse sinus DAVF with a shunt point limited to the dural sinus wall, causing cortical venous reflux, were successfully treated with endovascular transarterial Onyx embolization. The Onyx cast showed multiple feeders from the occipital and middle meningeal arteries aggregated in the arachnoid granulation (AG), which dilated the draining vein. CONCLUSION: Non-sinus-type DAVFs with shunt points located on the AG may be one of the presentations of an on-the-wall-type DAVF.

DOI： 10.25259/SNI_930_2023

PubMed

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嚢胞形成PRL産生PitNETの治療成績

岡田正康, 小倉良介, 平石哲也, 米岡有一郎, 大石誠

新潟医学会雑誌 137 ( 12 ) 447 - 447 2023.12

未破裂内頸動脈後交通動脈分岐部瘤に対する血管内治療の現状と課題

藤原秀元, 長谷川仁, 鈴木倫明, 澁谷航平, 吉田至誠, 大石誠

脳血管内治療 8 ( Suppl. ) S440 - S440 2023.11

CFDによる破裂脳動脈瘤のブレブ血流解析破裂点となり得るブレブの血行力学的特徴

鈴木倫明, 長谷川仁, 吉田至誠, 渋谷航平, 藤原秀元, 大石誠

脳血管内治療 8 ( Suppl. ) S264 - S264 2023.11

破裂脳動脈瘤に対する当院における血管内治療の現状

鈴木倫明, 長谷川仁, 吉田至誠, 渋谷航平, 藤原秀元, 大石誠

脳血管内治療 8 ( Suppl. ) S310 - S310 2023.11

横-S状静脈洞部硬膜動静脈瘻難治例の特徴

吉田至誠, 渋谷航平, 藤原秀元, 鈴木倫明, 長谷川仁, 大石誠

脳血管内治療 8 ( Suppl. ) S199 - S199 2023.11

PICA and ASA involved typeの出血性解離性椎骨動脈瘤に対し,急性期にステント支援下コイル塞栓術を行い,慢性期にOA-PICA bypass併用コイル塞栓術を行った1例

鈴木倫明, 長谷川仁, 澁谷航平, 齋藤太希, 高橋陽彦, 大石誠, 藤井幸彦

脳卒中の外科 51 ( 6 ) 513 - 519 2023.11

Language：Japanese Publisher：(一社)日本脳卒中の外科学会

後下小脳動脈(posterior inferior cerebellar artery:PICA)と前脊髄動脈(anterior spinal artery:ASA)の双方を含むdominant sideの破裂解離性椎骨動脈瘤(ruptured vertebral artery dissecting aneurysm:rVADA)に対して,急性期にステント併用コイル塞栓術(stent-assisted coiling:SAC)を行い,再発を認めたため慢性期にOA-PICA bypass併用コイル塞栓術を行った症例を経験したので報告する.症例は50歳男性.突然の頭痛.全身痙攣にて発症.後頭蓋窩に厚いくも膜下出血を認め(Hunt and Kosnik grade III),dominant sideの左VAに破裂解離性椎骨動脈瘤を認めた.PICA and ASA involved typeのrVADAに対して,破裂急性期にSACにてPICAとASAの血流を温存して破裂部位を中心にコイル塞栓を行った.しかしながら,術後8日目にminor bleedingを認めたため,破裂部位の追加塞栓を行った.その後は自宅退院となり(mRS1),再出血を認めず経過していたが,術後2ヵ月目に偽腔の開大を認めたため,後頭動脈(occipital artery:OA)-PICA bypassを併用した解離部のコイル塞栓術を行い,最終的に根治することができた.Dominant side VAにおけるPICA and ASA involved type rVADAに対して破裂急性期のSACによるreconstructive treatmentと慢性期におけるOA-PICA bypass併用によるコイル塞栓術は有効な治療選択肢の1つとなり得る.(著者抄録)

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Other Link： https://search.jamas.or.jp/default/link?pub_year=2023&ichushi_jid=J02079&link_issn=&doc_id=20231212130008&doc_link_id=%2Fcp4strok%2F2023%2F005106%2F008%2F0513-0519%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fcp4strok%2F2023%2F005106%2F008%2F0513-0519%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

脳AVMに対する血管内治療の進歩と調和脳動静脈奇形に対する塞栓術の進歩と調和

長谷川仁, 鈴木倫明, 澁谷航平, 藤原秀元, 大石誠

脳血管内治療 8 ( Suppl. ) S73 - S73 2023.11

Clinical, imaging, and molecular features of radiation-induced glioblastomas developing more than 20 years after radiation therapy for intracranial germinomatous germ cell tumor: illustrative cases. International journal

Yoshihiro Tsukamoto, Manabu Natsumeda, Haruhiko Takahashi, Asuka Ueno, Kiichi Sakai, Kazuki Shida, Hiroki Seto, Taiki Saito, Satoshi Shibuma, Yoko Nakayama, Yuki Tanaka, Toshimichi Nakano, Atsushi Ohta, Katsuya Maruyama, Masayasu Okada, Takeyoshi Eda, Yasuhiro Seki, Yuichirou Yoneoka, Hiroshi Shimizu, Kouichirou Okamoto, Akiyoshi Kakita, Makoto Oishi

Journal of neurosurgery. Case lessons 6 ( 16 ) 2023.10

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Germinomatous germ cell tumor is highly sensitive to chemoradiotherapy; patients are expected to survive for decades. Many radiation-induced malignant gliomas (RIMGs) occur >10 years after radiotherapy. Standard therapy for RIMGs has not been established because of the lesion's rarity, the patient's shorter survival period, and the risk of radiation necrosis by repeat radiation. OBSERVATIONS: Two patients, a 32-year-old man and a 50-year-old man, developed glioblastomas more than 20 years after radiation monotherapy for germinoma with or without mature teratoma. The first patient showed a tumor in the left frontotemporal region with disseminated lesions and died 2 months after partial resection of the tumor without responding to the chemotherapy with temozolomide and bevacizumab. Methylation classifier analysis classified the pathology as closest to diffuse pediatric-type high-grade glioma, Rtk1 subtype. The second patient showed a tumor mass in the brainstem and left cerebellar peduncle, which worsened progressively during chemotherapy with temozolomide and bevacizumab. The tumor transiently responded to stereotactic radiotherapy with the CyberKnife. However, the patient died of RIMG recurrence-related aspiration pneumonia 11 months after the biopsy. Methylation classifier analysis classified the pathology as closest to infratentorial pilocytic astrocytoma. LESSONS: Chemoradiotherapy may improve the survival of patients with RIMGs. Furthermore, molecular features may influence the clinical, locoregional, and pathological features of RIMG.

DOI： 10.3171/CASE23361

PubMed

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Investigation of Mechanical Thrombectomy in Elderly Patients over 85 Years Old: A Multicenter Study.

Kohei Shibuya, Hitoshi Hasegawa, Tomoaki Suzuki, Haruhiko Takahashi, Kei Nishiyama, Makoto Oishi, Yukihiko Fujii

Neurologia medico-chirurgica 63 ( 9 ) 393 - 399 2023.9

Language：English Publishing type：Research paper (scientific journal)

In Japan, which has a super-aging society, there are increasing opportunities to perform mechanical thrombectomy for the elderly; however, there is no recorded evidence of thrombectomy for the elderly. This study examined the usefulness of thrombectomy in the elderly. We retrospectively analyzed patient data using a multicenter acute ischemic stroke registry (NGT-FAST). We examined outcomes in patients 75 years and older who underwent thrombectomies between January 1, 2021, and December 31, 2021. The patients were divided into two groups: the 75-84-year-old group and the 85+-year-old group. There was no difference in the pretreatment National Institutes of Health Stroke Scale score or Alberta Stroke Program Early Computed Tomography Score between the two groups, but the 85+-year-old group had a significantly lower rate of pre-stroke modified Rankin Scale (mRS) score of 0-2. There were no differences in time from onset to treatment or effective recanalization rate, but complications tended to be more common in the 85+-year-old group. The number of patients with a good outcome at discharge (an mRS score of 0-3) was significantly lower in the 85+-year-old group than in the 75-84-year-old group. In addition, 90.9% of patients in the 85+-year-old group with a pre-stroke mRS score of 3 deteriorated after treatment. The pre-stroke mRS score is very important in determining the indication for thrombectomy in the elderly because their preoperative condition is more likely to influence the outcome than that of younger patients.

DOI： 10.2176/jns-nmc.2023-0039

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【「脳神経外科領域におけるPDTの現状と問題点」】当科における光線力学療法の経験および次世代への挑戦

棗田学, 温城太郎, 渡邉潤, 塚本佳広, 岡田正康, 小倉良介, 平石哲也, 大石誠, 藤井幸彦

日本レーザー医学会誌 44 ( 2 ) 95 - 101 2023.7

Language：Japanese Publisher：(NPO)日本レーザー医学会

2018年7月に当科に光線力学療法(photodynamic therapy:PDT)を導入してから2021年6月まで,当科でPDTを施行した悪性脳腫瘍症例の臨床的特徴および無増悪生存期間(progression free survival:PFS),全生存期間(overall survival:OS),主な合併症について検討した.初発膠芽腫9例におけるPFSの中央値は14ヵ月,OS中央値は未達であった.死亡例は早期に遠隔再発を来した1例のみであった.主な合併症は光過敏症が1例,脳表に可逆性のFLAIR高信号が3例,術後うつ状態が5例に認め,いずれも一過性であった.術後の長期間遮光管理が原因と思われるうつ症状には,早期遮光解除などの工夫が必要と思われた.実際の症例を提示し我々のPDT初期治療経験を紹介し,また,次世代治療と考える近赤外光線免疫療法(near-infrared photoimmunotherapy:NIR-PIT)の研究に関しても紹介する.NIR-PITは,癌細胞の表面抗原を標識とし,近赤外線照射により生じた熱エネルギーにより腫瘍細胞の細胞膜を破壊する画期的な治療法である.今回,我々は膠芽腫細胞株に特異的な表面抗原Xに対する抗体を用いたNIR-PITを行い,殺細胞効果を確認した.(著者抄録)

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Other Link： https://search.jamas.or.jp/default/link?pub_year=2023&ichushi_jid=J01213&link_issn=&doc_id=20230803380003&doc_link_id=10.2530%2Fjslsm.jslsm-44_0024&url=https%3A%2F%2Fdoi.org%2F10.2530%2Fjslsm.jslsm-44_0024&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_2.gif

【「脳神経外科領域におけるPDTの現状と問題点」】当科における光線力学療法の経験および次世代への挑戦

棗田学, 温城太郎, 渡邉潤, 塚本佳広, 岡田正康, 小倉良介, 平石哲也, 大石誠, 藤井幸彦

日本レーザー医学会誌 44 ( 2 ) 95 - 101 2023.7

Language：Japanese Publisher：(NPO)日本レーザー医学会

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Usefulness of silent magnetic resonance angiography for intracranial aneurysms treated with a flow re-direction endoluminal device. International journal

Tomoaki Suzuki, Hitoshi Hasegawa, Kouichirou Okamoto, Kazuhiro Ando, Kouhei Shibuya, Haruhiko Takahashi, Shoji Saito, Hidemoto Fujiwara, Makoto Oishi, Yukihiko Fujii

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 15910199231174546 - 15910199231174546 2023.5

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: Flow re-direction endoluminal device (FRED) is a novel dual-layer flow-diverting stent to treat cerebral aneurysms with high obliteration rates, however, it induces inevitable metal-related artifacts. We compared silent magnetic resonance angiography (MRA), a new MRA method using ultra-short time of echo and arterial spin-labeling, with conventional time-of-flight (TOF)-MRA for imaging aneurysms treated using FRED. METHODS: Between May 2020 and September 2022, 16 patients with unruptured internal carotid aneurysms treated using FRED simultaneously underwent silent MRA and TOF-MRA after treatment, with 36 follow-up sessions in total. Two observers independently graded the quality of intra-aneurysmal flow and stented parent arteries under both types of MRA from 1 (not visible) to 4 (nearly equal to digital subtraction angiography [DSA]), with reference to DSA images as a standard criterion. RESULTS: The mean scores for intra-aneurysmal flow and stented parent arteries were significantly better for silent MRA (3.93 ± 0.21 and 3.82 ± 0.32, respectively) than for TOF-MRA (2.08 ± 0.99 and 1.92 ± 0.79, respectively) (P < 0.01). Intermodality agreements for intra-aneurysmal flow and stented parent arteries were 0.87 and 0.90, respectively. CONCLUSION: Silent MRA is superior to TOF-MRA for assessing patients treated with FRED, with potential as an alternative imaging modality to DSA.

DOI： 10.1177/15910199231174546

PubMed

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Superior Visualization of Neovascularization with Silent Magnetic Resonance Angiography Compared to Time-of-flight Magnetic Resonance Angiography after Bypass Surgery in Moyamoya Disease. International journal

Tomoaki Suzuki, Hitoshi Hasegawa, Kouichirou Okamoto, Kohei Shibuya, Haruhiko Takahashi, Hidemoto Fujiwara, Makoto Oishi, Yukihiko Fujii

World neurosurgery 2023.5

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: The evaluation of postsurgical neoangiogenesis in patients with moyamoya disease (MMD) is crucial for appropriate patient management. This study aimed to assess the visualization of neovascularization after bypass surgery using non-contrast-enhanced silent magnetic resonance angiography (MRA) with ultra-short echo time (UTE) and arterial spin labeling (ASL). METHODS: After bypass surgery, 13 patients with MMD were followed up for >6 months between September 2019 and November 2022. They underwent silent MRA in the same session as time-of-flight MRA (TOF-MRA) and digital subtraction angiography (DSA). Two observers independently rated the visualization of neovascularization in both types of MRA from 1 (not visible) to 4 (nearly equal to DSA), with reference to DSA images as the standard. RESULTS: The mean scores were significantly higher for silent MRA compared with TOF-MRA (3.81 ± 0.48 and 1.92 ± 0.70, respectively) (p <0.01). The inter-modality agreements were 0.83 and 0.71 for silent MRA and TOF-MRA, respectively. TOF-MRA depicted the donor artery and recipient cortical artery after direct bypass surgery, although fine neovascularization developed after indirect bypass surgery was poorly visualized. Silent MRA could reveal the developed bypass flow signal and perfused MCA territory, which was almost equal to the DSA images. CONCLUSIONS: Silent MRA achieves better visualization of postsurgical revascularization in patients with MMD than TOF-MRA. Moreover, it may have the potential to provide visualization of the developed bypass flow equivalent to DSA.

DOI： 10.1016/j.wneu.2023.04.119

PubMed

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胚種治療後20年以上経過後に発症した放射線誘発性膠芽腫の2症例の検討

塚本佳広, 高橋陽彦, 棗田学, 坂井貴一, 中山遥子, 田中裕貴, 岡本浩一郎, 大石誠, 柿田明美, 藤井幸彦

Brain Tumor Pathology 40 ( Suppl. ) 113 - 113 2023.5

FGFR3-TACC3 fusionを伴うIDH野生型神経膠腫はCTで石灰化を高率に有する

高橋陽彦, 棗田学, 塚本佳広, 清水宏, 岡本浩一郎, 峰晴陽平, 荒川芳輝, 大石誠, 柿田明美, 藤井幸彦

Brain Tumor Pathology 40 ( Suppl. ) 099 - 099 2023.5

プロラクチン産生下垂体腺腫が頸部に転移したPit-1陽性下垂体がんの一例

岡田正康, 植木雄志, 棗田学, 大石誠, 近藤修平, 梅津哉, 柿田明美, 藤井幸彦

Brain Tumor Pathology 40 ( Suppl. ) 144 - 144 2023.5

プロラクチン産生下垂体腺腫が頸部に転移したPit-1陽性下垂体がんの一例

岡田正康, 植木雄志, 棗田学, 大石誠, 近藤修平, 梅津哉, 柿田明美, 藤井幸彦

Brain Tumor Pathology 40 ( Suppl. ) 144 - 144 2023.5

TP53変異を有する脈絡叢癌培養細胞株の樹立およびマルチオミクス解析

棗田学, 温城太郎, 塚本佳広, 岡田正康, 大石誠, 久保暢大, 申将守, 今村勝, 今井千速, シャヘンダ・エル・ナガール, 藤井幸彦

新潟医学会雑誌 137 ( 5 ) 186 - 186 2023.5

Administration of glucocorticoids prior to liquid biopsy dramatically reduces the detection rate of <i>MYD88 L265P</i> mutation in cerebrospinal fluid of primary CNS lymphoma patients

Haruhiko Takahashi, Manabu Natsumeda, Jotaro On, Jun Watanabe, Mari Tada, Hiroshi Shimizu, Yoshihiro Tsukamoto, Masayasu Okada, Makoto Oishi, Jun Takizawa, Yasuhiko Hayashi, Yasufumi Masaki, Akiyoshi Kakita, Yukihiko Fujii

Leukemia & Lymphoma 64 ( 6 ) 1219 - 1222 2023.4

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Papers - OOISHI Makoto