Updated on 2023/06/07


Academic Assembly Institute of Medicine and Dentistry IGAKU KEIRETU Assistant Professor
Graduate School of Medical and Dental Sciences Community Disease Control Community Preventive Medicine Assistant Professor
Assistant Professor
External link


  • 博士(医学) ( 2010.3   新潟大学 )

Research Areas

  • Life Science / Forensics medicine

Research History

  • Niigata University   Institute of Medicine and Dentistry, Academic Assembly   Assistant Professor


  • Niigata University   Community Preventive Medicine, Community Disease Control, Graduate School of Medical and Dental Sciences   Assistant Professor


  • Niigata University   Graduate School of Medical and Dental Sciences   Specially Appointed Assistant Professor

    2017.9 - 2022.6

  • Niigata University   Graduate School of Medical and Dental Sciences Molecular and Cellular Medicine Molecular Genetics   Specially Appointed Assistant Professor

    2010.4 - 2012.3

Qualification acquired

  • Dentist



  • Bcl11b prevents the intrathymic development of innate CD8 T cells in a cell intrinsic manner. Reviewed

    Hirose S, Touma M, Go R, Katsuragi Y, Sakuraba Y, Gondo Y, Abe M, Sakimura K, Mishima Y, Kominami R

    International immunology   27 ( 4 )   205 - 215   2015.4

  • Cell of origin in radiation-induced premalignant thymocytes with differentiation capability in mice conditionally losing one Bcl11b allele. Reviewed

    Go R, Hirose S, Katsuragi Y, Obata M, Abe M, Mishima Y, Sakimura K, Kominami R

    Cancer science   104 ( 8 )   1009 - 1016   2013.8

  • Impairment in differentiation and cell cycle of thymocytes by loss of a Bcl11b tumor suppressor allele that contributes to leukemogenesis. Reviewed

    Go R, Takizawa K, Hirose S, Katsuragi Y, Aoyagi Y, Mishima Y, Kominami R

    Leukemia research   36 ( 8 )   1035 - 1040   2012.8

  • Bcl11b heterozygosity promotes clonal expansion and differentiation arrest of thymocytes in gamma-irradiated mice. Reviewed

    Go R, Hirose S, Morita S, Yamamoto T, Katsuragi Y, Mishima Y, Kominami R

    Cancer science   101 ( 6 )   1347 - 1353   2010.6

  • Clonally expanding thymocytes having lineage capability in gamma-ray-induced mouse atrophic thymus. Reviewed

    Yamamoto T, Morita S, Go R, Obata M, Katsuragi Y, Fujita Y, Maeda Y, Yokoyama M, Aoyagi Y, Ichikawa H, Mishima Y, Kominami R

    International journal of radiation oncology, biology, physics   77 ( 1 )   235 - 243   2010.5

Research Projects

  • Identification of cells of origin in lymphomas and the target of γ-radiation

    Grant number:23710067

    2011 - 2012

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)

    Research category:Grant-in-Aid for Young Scientists (B)

    Awarding organization:Japan Society for the Promotion of Science

    GO Rieka

      More details

    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

    Cell of origin in γ-radiation induced mouse thymic lymphomas remains obscure. In this study, we generated mouse models in which loss of one Bcl11b allele occurs in thymocytes at different developmental stages and examined expansion and differentiation of premalignant thymocytes after irradiation. We showed that thymocytes at the immature stage were cells of origin and premalignant thymocytes retained the capacity to proliferate and differentiate. Also, loss of Bcl11b allele in thymocytes led to impaired cell cycle arrest at S phase after irradiation, suggesting that the impairment contributes to the development of the premalignant thymocytes.



Teaching Experience

  • 医学論文を読む(ジャーナルクラブ)A

    Institution name:新潟大学

  • 医療と法

    Institution name:新潟大学

  • 歯科法医学

    Institution name:新潟大学

  • 特別授業 歯科法医学

    Institution name:新潟大学