2025/08/25 更新

写真a

ワタナベ タツノリ
渡部 達範
WATANABE Tatsunori
所属
医歯学総合病院 麻酔科 講師
職名
講師
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外部リンク

学位

  • 博士(医学) ( 2015年9月   新潟大学 )

研究キーワード

  • 術後鎮痛

  • 末梢神経ブロック

  • 薬物動態

  • フラビン蛋白蛍光イメージング

  • 麻酔

研究分野

  • ライフサイエンス / 解剖学

  • ライフサイエンス / 薬理学

  • ライフサイエンス / 医療薬学

  • ライフサイエンス / 生理学

  • ライフサイエンス / 麻酔科学

経歴(researchmap)

  • 新潟大学   医歯学総合病院 麻酔科   講師

    2023年4月 - 現在

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  • 新潟大学   地域医療教育センター魚沼基幹病院   特任講師

    2019年4月 - 2023年3月

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  • 新潟大学   手術部   助教

    2016年2月 - 2019年3月

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  • 新潟大学   麻酔科   特任助教

    2015年9月 - 2016年2月

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  • 新潟大学   Brain Research Institute

    2011年4月 - 2015年9月

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  • 新潟大学   麻酔科   医員

    2010年8月 - 2011年3月

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  • 新潟県立中央病院   麻酔科

    2009年4月 - 2010年7月

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  • 長岡赤十字病院   麻酔科

    2008年4月 - 2009年3月

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  • 新潟大学   麻酔科   医員

    2007年4月 - 2008年3月

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  • 新潟大学   Medical and Dental Hospital   臨床研修医

    2005年4月 - 2007年3月

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経歴

  • 新潟大学   医歯学総合病院 麻酔科   講師

    2023年4月 - 現在

  • 新潟大学   医歯学総合病院 魚沼地域医療教育センター   特任講師

    2019年4月 - 2023年3月

  • 新潟大学   医歯学総合病院 手術部   助教

    2016年2月 - 2019年3月

  • 新潟大学   医歯学総合病院 麻酔科   特任助教

    2014年5月 - 2016年1月

学歴

  • 新潟大学   システム脳生理学

    2011年4月 - 2015年9月

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  • 新潟大学   医学部   医学科

    1999年4月 - 2005年3月

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所属学協会

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論文

  • Sternal Nonunion Treated by Radiofrequency Thermocoagulation of the Anterior Cutaneous Branch of the Intercostal Nerve: A Case Report. 国際誌

    Tatsunori Watanabe, Hiroshi Baba

    Pain medicine case reports   9 ( 2 )   123 - 126   2025年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: For painful sternal nonunion, conservative treatment by radiofrequency thermocoagulation nerve block of the anterior cutaneous branch of the intercostal nerve can be indicated when surgery is not feasible. CASE REPORT: A 44-year-old man with a history of open-heart surgery was referred to our department due to a complaint that was strongly suspected to be associated with stress. He wished to restart archery, however, doing so was difficult due to the painful sternal nonunion. Surgical treatment and external fixation were not appropriate due to his past medical history and desire to resume archery. Radiofrequency thermocoagulation (90°C, 120 seconds) of the anterior cutaneous branch of the intercostal nerve was performed because he had only 2 tender points. After performing thermocoagulation several times to achieve long-term analgesia, the patient was allowed to resume archery. CONCLUSIONS: Radiofrequency intercostal nerve thermocoagulation is an effective conservative treatment for sternal nonunion pain.

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  • Identifying nerve to vastus medialis at adductor canal entry. 査読

    Tatsunori Watanabe, Hisashi Mera, Yutaka Seino

    Journal of anesthesia   37 ( 5 )   813 - 814   2023年10月

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  • Significantly earlier ambulation and reduced risk of near-falls with continuous infusion nerve blocks: a retrospective pilot study of adductor canal block compared to femoral nerve block in total knee arthroplasty 査読 国際誌

    Yutaka Fujita, Hisashi Mera, Tatsunori Watanabe, Kenta Furutani, Haruna O. Kondo, Takao Wakai, Hiroyuki Kawashima, Akira Ogose

    BMC Musculoskeletal Disorders   23 ( 1 )   768 - 768   2022年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Science and Business Media LLC  

    Abstract

    Background

    Near-falls should be detected to prevent falls related to the earlier ambulation after Total knee arthroplasty (TKA). The quadriceps weakness with femoral nerve block (FNB) has led to a focus on adductor canal block (ACB). We purposed to examine the risk of falls and the earlier ambulation in each continuous infusion nerve block.

    Methods

    Continuous infusion nerve block (FNB or ACB) was performed until postoperative day (POD) 2 or 3. Pain levels and falls/near-falls with knee-buckling were monitored from POD 1 to POD 3. The score on the manual muscle test, MMT (0 to 5, 5 being normal), of the patients who could ambulate on POD 1, was investigated.

    Results

    A total of 73 TKA cases, 36 FNB and 37 ACB, met the inclusion criteria. No falls were noted. But episodes of near-falls with knee-buckling were witnessed in 14 (39%) cases in the FNB group and in 4 (11%) in the ACB group (p = 0.0068). In the ACB group, 81.1% of patients could ambulate with parallel bars on POD 1, while only 44.4% of FNB patients could do so (p = 0.0019). The quadriceps MMT values in the ACB group was 2.82, significantly higher than 1.97 in the FNB group (p = 0.0035). There were no significant differences in pain as measured with a numerical rating scale (NRS) and rescue analgesia through POD 3.

    Conclusion

    ACB was associated with significantly less knee-buckling and earlier ambulation post-TKA, with better quadriceps strength. Our study indicated the incidence of falls and near-falls with continuous infusion nerve blocks, and support the use of ACB to reduce the risk of falls after TKA. It is suggested that a certain number of the patients even with continuous ACB infusion should be considered with the effect of motor branch to prevent falls.

    DOI: 10.1186/s12891-022-05735-6

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    その他リンク: https://link.springer.com/article/10.1186/s12891-022-05735-6/fulltext.html

  • Continuous ulnar nerve block at the forearm for early active mobilisation following flexor tendon reconstruction. 査読 国際誌

    T Watanabe, K Kamimura, M Shirahata, K Moriya

    Anaesthesia reports   10 ( 2 )   e12180   2022年

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    記述言語:英語  

    A 63-year-old woman had sustained a subcutaneous rupture of the flexor digitorum profundus tendon of the little finger due to osteoarthritis of the pisotriquetral joint. She underwent excision of the pisiform bone and reconstruction of the flexor digitorum profundus tendon of the little finger using an autogenous palmaris longus tendon graft. After surgery, a continuous ulnar nerve block was performed at the forearm under ultrasound and nerve stimulator guidance. During rehabilitation, she could not actively extend her little finger independently due to the block; however, she could actively extend it when the dorsum of the metacarpophalangeal joint was pressed by the occupational therapist, resulting in successful early active mobilisation. A continuous ulnar nerve block at the forearm may help to facilitate early active mobilisation after reconstructive surgery for little finger flexor tendon rupture. However, it may restrict the active extension of the little finger because the block does not spare the innervation of the intrinsic muscles responsible for little finger extension.

    DOI: 10.1002/anr3.12180

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  • High-flow nasal cannula oxygen therapy was effective for dysphagia associated with respiratory muscle paralysis due to cervical spinal cord injury: A case report. 査読 国際誌

    Yoshihiro Watanabe, Toshiaki Tamura, Ryota Imai, Koki Maruyama, Mayumi Iizuka, Satomi Ohashi, Seigo Yamaguchi, Tatsunori Watanabe

    Medicine   100 ( 32 )   e26907   2021年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    RATIONALE: Respiratory muscle paralysis due to low cervical spinal cord injury (CSCI) can lead to dysphagia. Noninvasive positive airway pressure (PAP) therapy can effectively treat this type of dysphagia. High-flow nasal cannula (HFNC) oxygen therapy can generate a low level of positive airway pressure resembling PAP therapy, it may improve the dysphagia. PATIENT CONCERNS: The patient was an 87-year-old man without preexisting dysphagia. He suffered a CSCI due to a dislocated C5/6 fracture, without brain injury, and underwent emergency surgery. Postoperatively (day 2), he complained of dysphagia, and the intervention was initiated. DIAGNOSIS: Based on clinical findings, dysphagia in this case, may have arisen due to impaired coordination between breathing and swallowing, which typically occurs in patients with CSCI who have reduced forced vital capacity. INTERVENTIONS: HFNC oxygen therapy was started immediately after the surgery, and swallowing rehabilitation was started on Day 2. Indirect therapy (without food) and direct therapy (with food) were applied in stages. HFNC oxygen therapy appeared to be effective because swallowing function temporarily decreased when the HFNC oxygen therapy was changed to nasal canula oxygen therapy. OUTCOMES: Swallowing function of the patient improved and he did not develop aspiration pneumonia. LESSONS: HFNC oxygen therapy improved swallowing function in a patient with dysphagia associated with respiratory-muscle paralysis following a CSCI. It may have prolonged the apnea tolerance time during swallowing and may have improved the timing of swallowing. HFNC oxygen therapy can facilitate both indirect and direct early swallowing therapy to restore both swallowing and respiratory function.

    DOI: 10.1097/MD.0000000000026907

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  • SUZYTM forceps facilitate nasogastric tube insertion under McGRATHTM MAC videolaryngoscopic guidance: A randomized, controlled trial. 査読 国際誌

    Kenta Furutani, Tatsunori Watanabe, Keiichiro Matsuda, Yoshinori Kamiya, Hiroshi Baba

    Medicine   99 ( 41 )   e22545   2020年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Nasogastric tubes can be easily inserted in patients under general anesthesia. However, for difficult cases, insertion techniques that can be used in routine clinical practice are limited. SUZY forceps are designed for the removal of pharyngolaryngeal foreign bodies under guidance of a McGrath videolaryngoscope. We hypothesized that using SUZY forceps under McGrath videolaryngoscopic guidance may facilitate nasogastric tube insertion and tested this in a randomized controlled trial. METHODS: Adult patients who underwent gastrointestinal or hepato-pancreato-biliary surgery were randomly allocated to 2 groups; the SUZY group and the Magill group. Patients, nurses, and all clinical staff except for the attending anesthesiologist were blinded to group assignment throughout the study. After anesthesia induction, insertion of the nasogastric tube was performed by skilled anesthesiologists with either SUZY or Magill forceps according to group allocation under McGrath videolaryngoscopic guidance. The primary endpoint was insertion time which was defined as the time required to advance the nasogastric tube by 55 cm from the nostril. Secondary endpoints were the success rates of the nasogastric tube insertion, which were defined as a 55-cm advancement from the nostril at the 1st, 2nd, and 3rd attempt, proper insertion rate, the severity of pharyngolaryngeal complications, and hemodynamic parameters during nasogastric tube insertion. RESULTS: Sixty patients were randomized and none of these patients were excluded from the final analysis. The median [interquartile range] insertion time was 25 [18-33] seconds in the SUZY group, and 33 [21-54] seconds in the Magill group (P = .02). Success rates were not different between the groups (97% and 80% in the SUZY and Magill group at 1st attempt, respectively, P = .10). Both, the severity score of the mucosal injury and the severity of sore throat were higher in the Magill than in the SUZY group, whereas the degree of hoarseness did not differ between the 2 groups. Hemodynamic parameters were not significantly different between the groups. CONCLUSION: Using SUZY forceps under McGrath videolaryngoscopic guidance reduced the time required to insert a nasogastric tube and the severity of pharyngolaryngeal complications, when compared to using Magill forceps.

    DOI: 10.1097/MD.0000000000022545

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  • Quadratus lumborum block type 2 for pedicle groin flap analgesia: a case report. 査読 国際誌

    Tatsunori Watanabe, Koji Moriya, Hiroshi Baba

    JA clinical reports   6 ( 1 )   36 - 36   2020年5月

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  • Acute spatial spread of NO-mediated potentiation during hindpaw ischaemia in mice. 査読 国際誌

    Takeshi Onishi, Tatsunori Watanabe, Mika Sasaki, Yoshinori Kamiya, Masao Horie, Hiroaki Tsukano, Ryuichi Hishida, Tatsuro Kohno, Hirohide Takebayashi, Hiroshi Baba, Katsuei Shibuki

    The Journal of physiology   597 ( 13 )   3441 - 3455   2019年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    KEY POINTS: Neuropathic pain spreads spatially beyond the injured sites, and the mechanism underlying the spread has been attributed to inflammation occurring in the spinal cord. However, the spatial spread of spinal/cortical potentiation induced by conduction block of the peripheral nerves can be observed prior to inflammation. In the present study, we found that spreading potentiation and hypersensitivity acutely induced by unilateral hindpaw ischaemia are nitric oxide (NO)-dependent and that NO is produced by ischaemia and quickly diffuses within the spinal cord. We also found that NO production induced by ischaemia is not observed in the presence of an antagonist for group II metabotropic glutamate receptors (mGluRs) and that neuronal NO synthase-positive dorsal horn neurons express group II mGluRs. These results suggest strongly that NO-mediated spreading potentiation in the spinal cord is one of the trigger mechanisms for neuropathic pain. ABSTRACT: Cortical/spinal responses to hindpaw stimulation are bilaterally potentiated by unilateral hindpaw ischaemia in mice. We tested the hypothesis that hindpaw ischaemia produces nitric oxide (NO), which diffuses in the spinal cord to induce spatially spreading potentiation. Using flavoprotein fluorescence imaging, we confirmed that the spreading potentiation in hindpaw responses was induced during ischaemia in the non-stimulated hindpaw. This spreading potentiation was blocked by spinal application of l-NAME, an inhibitor of NO synthase (NOS). Furthermore, no spreading potentiation was observed in neural NOS (nNOS) knockout mice. Spinal application of an NO donor was enough to induce cortical potentiation and mechanical hypersensitivity. The spatial distribution of NO during unilateral hindpaw ischaemia was visualized using 4-amino-5-methylamino-2',7'-difluorofluorescein (DAF-FM). An increase in fluorescence derived from the complex of DAF-FM with NO was observed on the ischaemic side of the spinal cord. A similar but smaller increase was also observed on the contralateral side. Somatosensory potentiation after hindpaw ischaemia is known to be inhibited by spinal application of LY354740, an agonist of group II metabotropic glutamate receptors (mGluRs). We confirmed that the spinal DAF-FM fluorescence increases during hindpaw ischaemia were not observed in the presence of LY354740. We also confirmed that approximately half of the nNOS-positive neurons in the superficial laminae of the dorsal horn expressed mGluR2 mRNA. These results suggest that disinhibition of mGluR2 produces NO which in turn induces a spreading potentiation in a wide area of the spinal cord. Such spreading, along with the consequent non-specific potentiation in the spinal cord, may trigger neuropathic pain.

    DOI: 10.1113/JP277615

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  • Neural block therapy for radiation enteritis: a case report. 査読 国際誌

    Moegi Tanaka, Yoshinori Kamiya, Hiroki Shimizu, Tatsunori Watanabe, Natsuko Naito, Hiroshi Baba

    JA clinical reports   5 ( 1 )   20 - 20   2019年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Radiation enteritis following radiotherapy targeting the abdomen occasionally causes ulcers or ileus, which can be difficult to treat and usually progressive and refractory, significantly degrading the patient's quality of life. CASE PRESENTATION: A 58-year-old woman had undergone surgery for cervical cancer approximately 21 years ago. During treatment, she had also received radiotherapy targeting the pelvis and stomach. She presented with complaints of vomiting and lower abdominal pain and was subsequently diagnosed with multiple gastric ulcers, enterocolitis, and paralytic ileus due to late radiation-induced sequelae. We reasoned that visceral sympathetic block would improve the abdominal symptoms; therefore, we performed a splanchnic nerve block and an inferior mesenteric artery plexus block. As predicted, these block procedures improved the symptoms. CONCLUSIONS: Radiation enteritis is an iatrogenic disease, and there is no established treatment for intractable cases. However, visceral sympathetic nerve block may show efficacy as a potential therapy for radiation enteritis-associated abdominal pain and ileus.

    DOI: 10.1186/s40981-019-0239-9

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  • Effect of remifentanil on postoperative nausea and vomiting: a randomized pilot study. 査読

    Tatsunori Watanabe, Koji Moriya, Naoto Tsubokawa, Hiroshi Baba

    Journal of anesthesia   32 ( 5 )   781 - 785   2018年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Opioid-related postoperative nausea and vomiting should not occur following remifentanil administration because of its relatively short time to elimination. However, studies have indicated that the incidence of postoperative nausea and vomiting associated with remifentanil is similar to that with other opioids. Hence, we aimed to determine whether intraoperative remifentanil itself is associated with postoperative nausea and vomiting when postoperative pain is managed without opioid use. In this prospective pilot study, 150 patients who underwent unilateral upper limb surgery under general anesthesia with brachial plexus block were included. Patients in the remifentanil and control groups received 0.5 µg/kg/min remifentanil and saline, respectively. Postoperative pain was managed using a brachial plexus block, non-steroidal anti-inflammatory drugs, and acetaminophen. The presence of postoperative nausea and vomiting within the first 24 h after anesthesia was assessed by an evaluator blinded to patient allocation. Eight patients were excluded from the final analysis, resulting in 72 and 70 patients in the remifentanil and control groups, respectively. Postoperative nausea and vomiting within 24 h after surgery occurred in 11 and 9 patients in the remifentanil and control groups, respectively. These data suggest that remifentanil use only minimally affects the incidence of postoperative nausea and vomiting under sevoflurane anesthesia. UMIN Clinical Trials Registry identification number: UMIN000016110.

    DOI: 10.1007/s00540-018-2550-4

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  • Significant decreases in blood propofol concentrations during adrenalectomy for phaeochromocytoma 査読

    Tatsunori Watanabe, Haruhiko Hiraoka, Takuya Araki, Daisuke Nagano, Tohru Aomori, Tomonori Nakamura, Koujirou Yamamoto, Hiroshi Baba

    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY   83 ( 10 )   2205 - 2213   2017年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/bcp.13334

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  • Comparison of a curved forceps with a conventional straight forceps for nasogastric tube insertion under videolaryngoscopic guidance: A randomized, crossover manikin study. 査読 国際誌

    Kenta Furutani, Tatsunori Watanabe, Yoshinori Kamiya, Hiroshi Baba

    Medicine   96 ( 35 )   e7983   2017年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/MD.0000000000007983

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  • Evaluation of the diagnostic accuracy of nonverbal signs used by medical staff to assess postoperative pain 査読

    Tatsunori Watanabe, Reiko Okawa, Tsuyoshi Sato, Andrey B. Petrenko, Hiroshi Baba

    EUROPEAN JOURNAL OF ANAESTHESIOLOGY   34 ( 5 )   318 - 320   2017年5月

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  • Risk factors for rescue analgesic use on the first postoperative day after upper limb surgery performed under single-injection brachial plexus block: a retrospective study of 930 cases. 査読 国際誌

    Tatsunori Watanabe, Koji Moriya, Takuya Yoda, Naoto Tsubokawa, Andrey B Petrenko, Hiroshi Baba

    JA clinical reports   3 ( 1 )   39 - 39   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Background: Postoperative pain management after upper limb surgery is important for preventing adverse events that can prolong hospital stay and cause readmission. This study aimed to identify the risk factors associated with rescue analgesic use on the first postoperative day after upper limb surgery performed under single-injection brachial plexus block (BPB). Findings: We retrospectively analyzed records from 930 patients who underwent upper limb surgery under a single-injection BPB. Postoperatively, patients were administered oral loxoprofen regularly and rescue analgesics when analgesia was insufficient. We assessed the association between patient, surgical information, and rescue analgesic use on the first day after surgery (from 7:00 PM on the day of surgery to 7:00 AM on the first postoperative day), using a logistic regression model. Multivariate analysis revealed a significant association between rescue analgesic use and bone surgery, in particular, osteotomy, ligament repair and reconstruction, osteosynthesis, treatment for an amputated digit, and surgical duration. Conclusion: Bone surgery (osteotomy, ligament repair and reconstruction, osteosynthesis, treatment for an amputated digit) and a longer operative time were risk factors for rescue analgesic use for treating postoperative pain after upper limb surgery performed under single-injection BPB.

    DOI: 10.1186/s40981-017-0110-9

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  • Perforation of the superior vena cava 5 days after insertion of a central venous catheter through the left internal jugular vein 査読

    Miyuki Kurabe, Tatsunori Watanabe, Tatsuro Kohno

    JOURNAL OF CLINICAL ANESTHESIA   31   193 - 196   2016年6月

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  • The utility of anatomic diagnosis for identifying femoral nerve palsy following gynecologic surgery 査読

    Tatsunori Watanabe, Masayuki Sekine, Takayuki Enomoto, Hiroshi Baba

    JOURNAL OF ANESTHESIA   30 ( 2 )   317 - 319   2016年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00540-015-2113-x

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  • The effectiveness of combining remifentanil with propofol to achieve seizure adequacy in a patient undergoing modified electroconvulsive therapy 査読

    Tatsunori Watanabe, Kiyohiro Yoshinaga, Yutaro Suzuki, Toshiyuki Someya, Hiroshi Baba

    Japanese Journal of Anesthesiology   64 ( 10 )   1072 - 1075   2015年10月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Kokuseido Publishing Co. Ltd  

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  • Using lung ultrasound in an infant to detect bronchial intubation not previously identified by auscultation 査読

    Masataka Hiruma, Tatsunori Watanabe, Hiroshi Baba

    CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE   62 ( 10 )   1121 - 1122   2015年10月

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  • Spinal mechanisms underlying potentiation of hindpaw responses observed after transient hindpaw ischemia in mice 査読

    Tatsunori Watanabe, Mika Sasaki, Seiji Komagata, Hiroaki Tsukano, Ryuichi Hishida, Tatsuro Kohno, Hiroshi Baba, Katsuei Shibuki

    SCIENTIFIC REPORTS   5   11191   2015年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1038/srep11191

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  • Ultrasound-guided supraclavicular brachial plexus block in a patient with a cervical rib 査読

    Tatsunori Watanabe, Kazuhito Yanabashi, Koji Moriya, Yutaka Maki, Naoto Tsubokawa, Hiroshi Baba

    CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE   62 ( 6 )   671 - 673   2015年6月

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  • Prolonged apnea, caused by remifentanil, during awakening from anesthesia for emergency ventriculoperitoneal shunt placement 査読

    Tatsunori Watanabe, Yoshiko Watanabe, Daisuke Takizawa, Haruhiko Hiraoka, Andrey B. Petrenko, Hiroshi Baba

    JOURNAL OF ANESTHESIA   28 ( 2 )   320 - 321   2014年4月

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  • Hypnotic Effect of Propofol and Hypothalamic Nuclei: Are We Barking Up the Right Neurocircuitry? 査読

    Andrey B. Petrenko, Tatsunori Watanabe, Hiroshi Baba

    ANESTHESIA AND ANALGESIA   118 ( 2 )   484 - 484   2014年2月

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  • Efficacy of repeated subcostal transversus abdominis plane blocks with 0.2% lidocaine via 18-gauge intravenous catheters in patients undergoing abdominal aortic aneurism surgery 査読

    Goh Yamamoto, Tatsunori Watanabe, Takashi Fujiwara, Takashi Mochida, Ippei Watanabe, Tatsuro Kohno

    Japanese Journal of Anesthesiology   63 ( 8 )   866 - 871   2014年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Kokuseido Publishing Co. Ltd  

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  • Safety and beneficial effects of spinal morphine on the postoperative course of elderly patients undergoing surgical fixation of the femoral neck fracture 査読

    Tatsunori Watanabe, Takashi Fujiwara, Takashi Mochida, Ippei Watanabe, Hiroshi Baba

    Japanese Journal of Anesthesiology   62 ( 6 )   665 - 699   2013年6月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  • Anesthetic management of a patient with a giant ovarian tumor containing 83 l of fluid. 査読

    Bamba K, Watanabe T, Kohno T

    SpringerPlus   2   487   2013年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1186/2193-1801-2-487

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  • Alternative site for median nerve blockade allowing early functional rehabilitation after hand surgery 査読

    Tatsunori Watanabe, Ippei Watanabe, Masahiro Koizumi, Andrey B. Petrenko, Hiroshi Baba

    CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE   59 ( 1 )   58 - 62   2012年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s12630-011-9613-4

    Web of Science

    PubMed

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  • A case of sublingual hematoma following difficult laryngoscopy in a patient on anticoagulant therapy 査読

    Tatsunori Watanabe, Takashi Fujiwara, Misa Toyama, Takashi Mochida, Ippei Watanabe

    Japanese Journal of Anesthesiology   60 ( 1 )   100 - 103   2011年1月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    Scopus

    PubMed

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  • A case of central cord syndrome following thyroidectomy 査読

    Tatsunori Watanabe, Daisuke Takizawa, Tsuyoshi Sato, Hisashi Masaki, Michiya Ohkuro, Toshiyuki Tobita, Hiroshi Baba

    JOURNAL OF CLINICAL ANESTHESIA   22 ( 4 )   307 - 309   2010年6月

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書籍等出版物

  • 続・末梢神経ブロックの疑問〜実践編〜Q&A70

    渡部達範( 担当: 分担執筆 ,  範囲: 症例8 橈骨遠位端骨折Q34 Pattern②「腕神経叢ブロック(鎖骨下)」)

    2018年11月 

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  • 末梢神経ブロックの疑問Q&A70

    渡部達範( 担当: 分担執筆 ,  範囲: 鎖骨下アプローチ,ステロイド)

    中外医学社  2017年11月 

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  • 気道管理の疑問Q&A70

    渡部達範( 担当: 分担執筆 ,  範囲: BURP法について,マッキントッシュ型とミラー型の違いについて)

    中外医学社  2016年11月 

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  • 新麻酔科研修の素朴な疑問に答えます

    渡部達範( 担当: 分担執筆 ,  範囲: マンニトールが頭蓋内圧を低下させる機序は何か?)

    メディカルサイエンスインターナショナル  2016年9月 

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  • 気道管理に強くなる エビデンスに基づいた、確実に気道確保するための考え方・器具選び・テクニック

    渡部達範( 担当: 分担執筆 ,  範囲: AirQ)

    羊土社  2016年5月 

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  • 整形外科研修ノート 改訂第2版

    渡部達範( 担当: 分担執筆 ,  範囲: 局所浸潤麻酔の基礎と実際,伝達麻酔の基礎と実際)

    診断と治療社  2016年4月 

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  • 臨床に役立つ神経障害性痛の理解 【痛みのScience & Practice 8】

    渡部達範( 担当: 分担執筆 ,  範囲: I.神経障害性痛の発生機序 3.脳の機序)

    文光堂  2015年5月 

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  • 超音波ガイド下末梢神経ブロック 実践24症例

    渡部達範( 担当: 分担執筆 ,  範囲: 手指の遊離腱移植術に対する正中神経の持続選択的感覚ブロック)

    メディカル・サイエンス・インターナショナル  2013年5月 

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MISC

受賞

  • 最優秀演題賞

    2014年6月   日本麻酔科学会   一過性血流遮断によるしびれの脊髄機序: フラビン蛋白蛍光イメージング法を用いた解析

    渡部達範

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  • ポスター優秀賞

    2013年12月   運動器疼痛学会   フラビン蛋白蛍光イメージング法を用いた一過性虚血後のしびれの脊髄機構の解析

    渡部達範

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共同研究・競争的資金等の研究

  • フラビン蛋白蛍光イメージング法を用いた複合性局所疼痛症候群の脊髄機序の解明

    研究課題/領域番号:22K09019

    2022年4月 - 2025年3月

    制度名:科学研究費助成事業

    研究種目:基盤研究(C)

    提供機関:日本学術振興会

    渡部 達範

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    配分額:4160000円 ( 直接経費:3200000円 、 間接経費:960000円 )

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  • なぜ神経障害性疼痛は傷害された末梢神経の支配領域を超えて広がるのか?

    研究課題/領域番号:20H03775

    2020年4月 - 2023年3月

    制度名:科学研究費助成事業 基盤研究(B)

    研究種目:基盤研究(B)

    提供機関:日本学術振興会

    馬場 洋, 倉部 美起, 渡部 達範, 大西 毅

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    配分額:10660000円 ( 直接経費:8200000円 、 間接経費:2460000円 )

    令和3年度は週齢10週以上の大型成熟ラットから後根付き脊髄縦断スライスを作成できることを証明することができた。また、この縦断スライスを用いると後根進入部付近の後角細胞の興奮だけでなく、L5腰髄節から頭尾方向に少なくとも2分節くらいは脊髄後角神経細胞の興奮が広がることを証明することができた。また、従来の横断スライスと同様にオピオイドの投与により神経興奮の強さや興奮の広がる面積が縮小することを確認できた。さらに、bicuculline(GABA-A受容体拮抗薬)により興奮の強さが増強することや興奮の頭尾方向への広がりが大きくなることも観察することができた。以上のことから、後根付き脊髄縦断スライスを用いて、脊髄後角神経細胞の興奮の頭尾方向への広がりを評価できる方法論を確立できたと考えられる。
    また、脊髄の髄腔内にカテーテルを挿入する技術も確立できた。当初はカテーテルを脊髄腔内に挿入すると約半分のラットで何らかの神経障害が発生し、薬液の作用を観察できるような技術レベルではなかったが、現在ではほぼ全例で神経障害を起こすことなくカテーテルを挿入することが可能になった。そのカテーテルから、局所麻酔薬を注入すると後肢の運動麻痺が起こること、数時間で神経障害を起こすことなく麻痺から回復することも確認できた。逆に、bicucullineを注入すると疼痛閾値が明らかに低下すること、数時間で正常に戻ることも確認できた。以上のことから、トロンボスポンディンを含んだ薬液を注入する技術も確立できたと考えられる。

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  • 神経障害性疼痛における脊髄・脳連関の生理学的解析およびグリア細胞活性化機構の解明

    2017年4月 - 2020年3月

    制度名:科学研究費(基盤研究B)

    提供機関:日本学術振興会

    紙谷義孝

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    資金種別:競争的資金

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  • フラビン蛋白蛍光イメージング法による神経ブロック後に生じる反跳痛の機序解明

    2017年4月 - 2019年3月

    制度名:科学研究費助成事業(若手研究B)

    提供機関:日本学術振興会

    渡部達範

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    担当区分:研究代表者  資金種別:競争的資金

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  • カルシウム感受性蛍光タンパクを用いたスライス及びin vivo脊髄イメージング

    2015年4月 - 2017年3月

    制度名:科学研究費助成事業(挑戦的萌芽研究)

    提供機関:日本学術振興会

    紙谷義孝

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    資金種別:競争的資金

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  • フラビン蛋白蛍光イメージング法を用いた疼痛評価系の確立

    2015年4月 - 2017年3月

    制度名:科学研究費助成事業(若手研究B)

    提供機関:日本学術振興会

    渡部達範

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    担当区分:研究代表者  資金種別:競争的資金

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担当経験のある授業科目(researchmap)

  • 麻酔科学

    機関名:新潟大学医学部医学科

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