Organization
University Medical and Dental Hospital Uonuma Institute of Community Medicine Specially Appointed Lecturer
Title
Specially Appointed Lecturer
External link
OHASHI Kazumasa
Degree
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博士（医学） ( 2012.3 新潟大学 )
Research Areas
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Life Science / Respiratory medicine
Research History (researchmap)
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Niigata University Medical and Dental Hospital Specially Appointed Assistant Professor
2015.4
Research History
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Niigata University UONUMA CHIIKI IRYO KYOIKU CENTER, University Medical and Dental Hospital Specially Appointed Lecturer
2022.5
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Niigata University University Medical and Dental Hospital UONUMA CHIIKI IRYO KYOIKU CENTER JUNBISHITU Specially Appointed Assistant Professor
2015.4 - 2022.4
Papers
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Reduced GM-CSF autoantibody in improved lung of autoimmune pulmonary alveolar proteinosis. Reviewed
Ohashi K, Takada T, Nakata K, Tazawa R
Eur Respir J 39 777 - 780 2012
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Direct evidence that GM-CSF inhalation improves lung clearance in pulmonary alveolar proteinosis. Reviewed
Ohashi K, Takada T, Nakata K, Tazawa R
Respir Med. 106 284 - 293 2012
Research Projects
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Elucidation of the mechanism of polymyxin B column therapy for rapidly progressive interstitial lung disease
Grant number：17K09605
2017.4 - 2020.3
System name：Grants-in-Aid for Scientific Research
Research category：Grant-in-Aid for Scientific Research (C)
Awarding organization：Japan Society for the Promotion of Science
Ohashi Kazumasa
Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）
Some patients with rapid progressive interstitial lung disease (ILD) are resistant and fatal to steroids as well as immunosuppressants. We found that rapid progressive ILD treated with polymyxin B column therapy (PMX-DHP) on the first day of steroid pulse therapy had a significantly better prognosis than the other patients. The purpose of this study was to clarify the exacerbating factors of rapidly progressive ILD by comprehensively measuring the serum concentrations of 38 cytokines before PMX-DHP, after PMX-DHP, and after steroid pulse therapy. 14 patients treated with PMX-DHP and steroid pulse therapy for rapidly progressive ILD at our hospital were enrolled. Five cytokines were significantly decreased after PMX-DHP, and more decreased after steroid pulse therapy. However, only eotaxin was decreased after PMX-DHP (p<0.05), but increased after steroid pulse therapy (p<0.05).