記述言語：英語   掲載種別：研究論文（学術雑誌）  

PURPOSE: This study aimed to investigate the prevalence and risk factors of oropharyngeal candidiasis (OPC) and its pain associations during radiotherapy for head and neck cancer (HNC). METHODS: This retrospective observational study included 65 patients undergoing radiotherapy for HNC. OPC was assessed during the early and late phases of radiotherapy by visual inspection and/or oral culture. Pain was quantitatively assessed using the maximum opioid dose (oral morphine equivalent dose [MED]). The MEDs of the patients with and without OPC were compared. Multivariate analysis was performed to identify the independent risk factors of OPC. RESULTS: OPC was confirmed in 38 of 65 patients (58%) during radiotherapy. Visual inspection indicated OPC in only 9 of 65 patients (14%), with a low diagnostic rate of 24% (9/38). The median MED was significantly higher for the OPC (82.5 mg) than for the non-OPC (60.0 mg) group (P = 0.027). Multivariate analysis identified BMI < 22 (OR, 5.14 [95% CI 1.48-17.8]; P = 0.010) and mucositis grade ≥ 3 (OR, 5.17 [95% CI 1.60-6.7]; P = 0.006) as independent risk factors for OPC. CONCLUSION: The prevalence of OPC during radiotherapy was 58%, and its rate of detection via visual inspection alone was low. Significant pain requiring high MED was accompanied by OPC. Therefore, early diagnosis by oral culture and appropriate intervention is crucial for patients with suspected OPC, such as those with low BMI and mucositis grade ≥ 3, to complete planned radiotherapy and maintain their quality of life.

DOI： 10.1007/s00405-025-09548-w

PubMed

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掲載種別：研究論文（学術雑誌）  

DOI： 10.1002/osi2.70005

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記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）  

DOI： 10.1007/s00520-023-07786-4

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掲載種別：研究論文（学術雑誌）  

DOI： 10.3390/tomography9010009

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掲載種別：研究論文（学術雑誌）   出版者・発行元：IOS Press  

BACKGROUND: Suprahyoid muscles behavior during the tongue lifting movement has not yet been elucidated. OBJECTIVE: The purpose of this study was to investigate the potential of elastography imaging to examine developmental oral dysfunction in children and oral hypofunction in older adults using sonography. METHODS: Tongue pressure was measured using a manometer with a probe. The tongue pressure was measured with simultaneously scanning the geniohyoid muscle (GHM) and the anterior belly of the digastric muscle (DGM) using sonographic elastography. Sagittal images of the GHM and coronal images of the DGM were used for the strain ratio measurement. The strain ratio of the muscles was measured three times for each subject with the tongue pressure values of 0–30 kPa. RESULTS: The strain ratio of the GHM were higher than those of the DGM at tongue pressure of 10, 20 and 30 kPa. The strain ratio of the GHM increased as the tongue pressure increased in all participants. In contrast, the strain ratio of the DGM tended to slowly decrease as tongue pressure increased in female participants. CONCLUSION: Sonographic elastography is useful for visual and quantitative evaluation of elastic properties in suprahyoid muscles during tongue lifting movements.

DOI： 10.3233/bme-221414

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総ページ数：249p   記述言語：日本語

CiNii Books

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J-GLOBAL

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J-GLOBAL

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J-GLOBAL

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記述言語：日本語   出版者・発行元：(公社)日本超音波医学会  

J-GLOBAL

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記述言語：日本語   出版者・発行元：新潟歯学会  

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開催年月日： 2024年7月

記述言語：日本語   会議種別：口頭発表（一般）  

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開催年月日： 2023年1月 - 2023年2月

記述言語：日本語   会議種別：ポスター発表  

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