2021/06/24 更新

写真a

シンボリ カオリ
新堀 香織
SHIMBORI Kaori
所属
医歯学総合病院 耳鼻咽喉・頭頸部外科 助教
職名
助教
外部リンク

学位

  • 学士(医学) ( 2008年4月   新潟大学 )

経歴

  • 新潟大学   医歯学総合病院 耳鼻咽喉・頭頸部外科   助教

    2020年4月 - 現在

 

論文

  • Prediction of effectiveness of potassium-competitive acid blocker and serotonin noradrenaline reuptake inhibitor on abnormal sensation in the throat: use of patient-reported outcome measures (PROMs)

    Nao Takahashi, Kaori Ikeda, Genki Iwai, Kaori Shinbori, Hironori Baba, Takanobu Sasaki, Kuniyuki Takahashi, Yuka Morita, Arata Horii

    European Archives of Oto-Rhino-Laryngology278 ( 5 ) 1483 - 1489   2021年5月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Science and Business Media LLC  

    <title>Abstract</title><sec>
    <title>Purpose</title>
    To determine patients with abnormal sensation in the throat (AST) who would respond to potassium-competitive acid blocker (P-CAB) or serotonin noradrenaline reuptake inhibitor (SNRI) treatment.


    </sec><sec>
    <title>Methods</title>
    AST patients were randomly divided into two groups. Thirty-one and 21 patients received P-CAB and SNRI treatment, respectively. GETS-J, the Japanese version of Glasgow Edinburgh Throat Scales (GETS), consisted of three subscales of throat symptoms (globus sensation, pain/swelling of the throat, and dysphagia) and somatic distress due to the disease, Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (FSSG), and Hospital Anxiety and Depression Scale (HADS) were used before and after treatments. Responders to treatments were defined as those who showed 50% or more decrease in symptom scores or somatic distress.


    </sec><sec>
    <title>Results</title>
    Pre-treatment GETS-J pain/swelling scores and FSSG acid reflux scores were higher in P-CAB responders and decreased after treatment. Receiver operating characteristic curve for pain/swelling subscale had an area under the curve (AUC) of 0.792 to predict P-CAB responders and a score of 11 provided the best combination of sensitivity (62.5%) and specificity (80%). Somatic distress and HADS anxiety scores, but no other GETS-J symptom scores, decreased after SNRI treatment. Pre-treatment globus scores were lower in SNRI responders. AUC value for globus subscale to predict SNRI responders was 0.741 and a score of 6.5 provided the best combination of sensitivity (70%) and specificity (73%).


    </sec><sec>
    <title>Conclusions</title>
    Pain/swelling is a characteristic symptom in AST patients who respond to P-CAB treatment. SNRI treatment would be effective for somatic distress in cases with mild symptoms.


    </sec>

    DOI: 10.1007/s00405-020-06544-0

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    その他リンク: https://link.springer.com/article/10.1007/s00405-020-06544-0/fulltext.html

  • Successful transoral surgical closure of a hypopharyngeal pyriform sinus fistula: a case report

    Keisuke Yamazaki, Kaori Shinbori, Joe Omata, Yusuke Yokoyama, Hironori Baba, Naotaka Aizawa, Shigehisa Hashimoto, Arata Horii

    Acta Oto-Laryngologica Case Reports1 ( 1 ) 84 - 86   2016年1月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Informa UK Limited  

    DOI: 10.1080/23772484.2016.1244470

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    その他リンク: http://www.tandfonline.com/doi/pdf/10.1080/23772484.2016.1244470