Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

<title>Abstract</title>The clinical features of xerostomia induced by immune checkpoint inhibitors (ICI) are similar to those of Sjögren’s syndrome (SS), whereas the immunohistological and serological features are known to differ from those of SS. However, the radiologic imaging features of salivary glands are not yet well known. We report a case of a 56-year-old male patient diagnosed with ICI-induced xerostomia. The patient underwent various imaging examinations to investigate the condition of the salivary glands, which indicated the following: (1) less specific findings on contrast-enhanced computed tomography, (2) mixed with intermediate and low signal intensity on both <italic>T</italic>_{<italic>1</italic>}-weighted and fat-suppressed <italic>T</italic>_{<italic>2</italic>}-weighted magnetic resonance imaging and poor “salt and pepper” appearance on magnetic resonance sialography, and (3) multiple ovoid hypoechoic areas with hyperechoic bands without acute sialadenitis on ultrasound. These radiologic imaging findings suggested remarkable lymphocyte infiltration, which could be a characteristic of ICI-induced xerostomia.

DOI： 10.1007/s11282-020-00480-9

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Other Link： https://link.springer.com/article/10.1007/s11282-020-00480-9/fulltext.html

Language：Japanese   Publisher：(NPO)日本歯科放射線学会  

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Language：Japanese   Publisher：(NPO)日本歯科放射線学会  

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Language：English   Publishing type：Research paper (scientific journal)   Publisher：Wiley  

Objective: This study reviewed the literature addressing the use of a coupling medium to evaluate the extent of oral tongue squamous cell carcinoma (OTSCC) in intraoral sonography to assess the potentiality of this technique for the precise estimation of the depth of invasion (DOI). Methods: Studies for this paper were identified by a search of PubMed and manual searching of references from articles, using the search terms “lingual cancer” and “intraoral sonography” and their synonyms in the title and abstract fields. We excluded studies with no description of the coupling medium. Results: Fourteen studies were included in this study. Sterile or non-sterile gel was used in 11 studies; however, no description about the surrounding normal mucosa was provided in these studies. In two studies, a dedicated acoustic coupling polymer gel was used, and the normal mucosal layer was demonstrated as a hypoechoic line underlying the mucosal surface in one study. Although the first report of the DOI measurement was performed with degassed water, no clear interpretation of the basement level of the surrounding mucosa was presented. Conclusions: Insufficient studies were available in the appropriate use of acoustic coupling medium from the viewpoint of the interpretation of the detailed normal anatomical structure of the tongue mucosa. Further studies are required to establish a standardized technique for the estimation of DOI in OTSCC.

DOI： 10.1002/osi2.1110

Scopus

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Other Link： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/osi2.1110

Language：Japanese   Publisher：(NPO)日本歯科放射線学会  

口腔内超音波検査により小唾液腺の口腔内超音波正常像について検討した。口腔乾燥感を含め口腔内に自覚症状のない健常な成人20名(女性13名、男性7名、平均29.4歳)を対象とした。超音波診断装置には、本体としてHIVISION Preirusを、超音波プローブには日常臨床で口腔内超音波走査に使用しているホッケースティック型術中用小型リニアプローブEUP-O54Jを使用した。口唇腺は上下唇とも口腔粘膜直下に一〜二層になって分布が確認された。また、腺葉群の大きさはそれぞれ後方の口角付近の方が大きく、厚みに相当する短径は上唇で平均1.5mm、下唇で2.2mmであった。さらに、血流表示画像において腺葉群内部の血流の確認が可能であり、マイクロスコピーコイルを用いたMRIに近い画像所見を得ることが可能であったと判断された。

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Other Link： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2021&ichushi_jid=J00567&link_issn=&doc_id=20210406250001&doc_link_id=10.11242%2Fdentalradiology.60.35&url=https%3A%2F%2Fdoi.org%2F10.11242%2Fdentalradiology.60.35&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

Language：English   Publishing type：Research paper (scientific journal)   Publisher：IOS Press  

BACKGROUND: Lip closing functions have never been evaluated from the viewpoint of elastic properties. OBJECTIVES: The purpose of the present study was to investigate the behavior of the lower orbicularis oris muscle during a button-pull exercise to measure lip closing force and quantitatively evaluate its elastic properties using sonographic elastography. METHODS: Appropriate compression loads for elastography were randomly measured on one of three types of acoustic couplers on three examiners. Compression tests were performed on three types of acoustic couplers within the appropriate compression load. Using the acoustic coupler with the lowest elastic modulus, the strain ratio of the lower orbicularis oris muscle during lip closing was measured, and elastography was performed on six males under tension loads of 0–8 N. RESULTS: The intraclass correlation coefficient (1, 3) for the tension load of 0 N was 0.81. Elastography showed that the strain ratio values increased significantly (p &lt; 0.05) as the tension load increased. CONCLUSIONS: Combining the data obtained from lip closing test devices and sonographic elastography enabled the muscle performance to be evaluated objectively and accurately.

DOI： 10.3233/bme-201101

PubMed

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Language：Japanese   Publisher：新潟歯学会  

線維性異形成症(FD)は正常な骨組織が線維性結合組織で置換され増殖することを特徴とする非腫瘍性骨病変である。骨格成長後にはFDの増殖が静止するとされているが、成人期でも増大をきたすことがある。今回、上顎骨FDの減量手術後再増大をきたし、再び減量手術が必要となった症例を経験したので報告する。患者は42歳の男性。25歳の時に上顎骨FDの減量手術を施行されるも受診が途絶え、再増大による顔面非対称をきたしたため17年後に当科初診となった。顔面非対称改善と病変増大による機能障害の予防のため、右側上顎骨頬側と口蓋側の2回に分けて減量手術を行った。削除量の目安としてCT画像から3次元実体モデルを利用してサージカルガイドを制作し、術中の対称性確認と手術時間の短縮を行った。術後3年経過した現在、明らかな再増大はない。今回もあくまで減量手術であり、病巣の残遺に伴う病態変化の可能性についての患者教育とともに長期の経過管理が重要と考えられた。(著者抄録)

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Language：Japanese   Publisher：(NPO)日本口腔科学会  

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Language：Japanese   Publisher：(公社)日本超音波医学会  

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Language：Japanese   Publisher：医歯薬出版(株)  

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Language：Japanese   Publisher：(NPO)日本歯科放射線学会  

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Language：Japanese   Publisher：(NPO)日本歯科放射線学会  

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Language：Japanese   Publisher：(NPO)日本歯科放射線学会  

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Language：Japanese   Publisher：新潟歯学会  

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Event date： 2021.4 - 2021.5

Language：English   Presentation type：Poster presentation  

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Event date： 2020.7

Language：Japanese   Presentation type：Oral presentation (general)  

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Event date： 2018.10

Language：Japanese   Presentation type：Oral presentation (general)  

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Event date： 2018.7

Language：Japanese   Presentation type：Oral presentation (general)  

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Event date： 2017.11

Language：Japanese   Presentation type：Oral presentation (general)  

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