2024/05/23 更新

写真a

リユウ ナンキ
LIU NANXI
RIYU Nanki
所属
教育研究院 医歯学系 医学系列 助教
医学部 医学科 助教
医歯学総合研究科 生体機能調節医学専攻 機能再建医学 助教
職名
助教
外部リンク

学位

  • 医科学修士学位 ( 2017年3月   高知大学 )

経歴

  • 新潟大学   教育研究院 医歯学系 医学系列   助教

    2024年4月 - 現在

  • 新潟大学   医歯学総合研究科 生体機能調節医学専攻 機能再建医学   助教

    2024年4月 - 現在

  • 新潟大学   医学部 医学科   助教

    2024年4月 - 現在

  • 新潟大学   教育研究院 医歯学系   特任助教

    2022年10月 - 2024年3月

  • 新潟大学   医歯学総合研究科   特任助教

    2022年10月 - 2024年3月

  • 新潟大学   教育研究院 医歯学系   特任助手

    2021年10月 - 2022年9月

  • 新潟大学   医歯学総合研究科   特任助手

    2021年10月 - 2022年9月

▶ 全件表示

 

論文

  • Mental construction of object symbols from meaningless elements by Japanese macaques (Macaca fuscata). 国際誌

    Nanxi Liu, Atsuhiko Iijima, Yutaka Iwata, Kento Ohashi, Nobuyoshi Fujisawa, Toshikuni Sasaoka, Isao Hasegawa

    Scientific reports   12 ( 1 )   3566 - 3566   2022年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    When writing an object's name, humans mentally construct its spelling. This capacity critically depends on use of the dual-structured linguistic system, in which meaningful words are represented by combinations of meaningless letters. Here we search for the evolutionary origin of this capacity in primates by designing dual-structured bigram symbol systems where different combinations of meaningless elements represent different objects. Initially, we trained Japanese macaques (Macaca fuscata) in an object-bigram symbolization task and in a visually-guided bigram construction task. Subsequently, we conducted a probe test using a symbolic bigram construction task. From the initial trial of the probe test, the Japanese macaques could sequentially choose the two elements of a bigram that was not actually seen but signified by a visually presented object. Moreover, the animals' spontaneous choice order bias, developed through the visually-guided bigram construction learning, was immediately generalized to the symbolic bigram construction test. Learning of dual-structured symbols by the macaques possibly indicates pre-linguistic adaptations for the ability of mentally constructing symbols in the common ancestors of humans and Old World monkeys.

    DOI: 10.1038/s41598-022-07563-z

    PubMed

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  • Protective effects of the selective alpha1A-adrenoceptor antagonist silodosin against cyclophosphamide-induced cystitis in rats.

    Nanxi Liu, Shogo Shimizu, Takahiro Shimizu, Kumiko Nakamura, Masaki Yamamoto, Youichirou Higashi, Motoaki Saito

    Journal of pharmacological sciences   132 ( 1 )   71 - 77   2016年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    We investigated the protective effects of a selective α1A-adrenoceptor antagonist, silodosin (Silod) on urinary bladder function in cyclophosphamide (CYP)-induced cystitis rats, with and without desensitization of the capsaicin (CAP)-sensitive afferent nerve pathway. Male Wistar rats (310-400 g) were pretreated with Silod (0, 100, or 300 μg/kg/day, p.o.) for 1 week before cystometry, and were administered either CYP (150 mg/kg, i.p.) or saline 2 days before the experiment. In another experiment, the rats were treated with CAP (125 mg/kg, s.c.) 4 days before the cystometry. The rat bladders were harvested, weighed, and evaluated histologically. The cystometric evaluation showed significant reductions in the intercontraction interval (ICI), single voided volume (SVV), and bladder compliance in CYP-treated rats compared to those in the vehicle-treated rats. High-dose Silod or CAP treatment significantly increased the ICI and SVV in the CYP rats. However, high-dose Silod treatment did not increase the ICI and SVV in CAP-treated CYP rats. Treatment with Silod did not improve the bladder weight, edema, and leukocyte infiltration resulting from the CYP-induced bladder inflammation. These data suggest that blockade of α1-adrenoceptors by Silod inhibited the CAP-sensitive afferent pathway in rats with cystitis.

    DOI: 10.1016/j.jphs.2016.08.007

    PubMed

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