Faculty Profiles - HANZAWA Kazuhiko

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by acute thunderclap headaches with or without other neurological symptoms, and reversible multi-segmental vasoconstriction of the cerebral arteries. We describe the case of a 49-year-old woman presenting with severe, sudden-onset headaches and multi-segmental vasoconstriction of the cerebral arteries demonstrated on magnetic resonance angiography (MRA). Headaches disappeared within several days, and vasoconstriction of cerebral arteries was markedly improved 6 weeks after the onset. We therefore diagnosed RCVS. In addition to MRA, we repeatedly performed transcranial-color flow imaging (TC-CFI) and transcranial Doppler ultrasonography (TCD) to evaluate cerebral arterial blood flow and risk of cerebral infarction. The first TCD study was performed 6 weeks after the onset; 11 high-intensity transient signals (HITS) were detected in 30 min at the region of vasoconstriction in the right MCA. To the best of our knowledge, this is the first report of HITS-positive RCVS. Ten weeks after the onset, MRA demonstrated disappearance of cerebral arterial vasoconstriction, and TCD detected only 1 HITS in 30 min. Interestingly, TC-CFI still indicated elevated flow velocity in the bilateral MCAs. These findings suggest that TC-CFI may be more sensitive and useful than MRA for diagnosis of RCVS.

DOI： 10.2301/neurosonology.27.76

CiNii Article

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Incidence and clinical significance of internal jugular vein thrombosis in acute ischemic stroke

TSURUOKA Atsushi, SHIMIZU Takahiro, MIZUKAMI Heisuke, SHIMODE Atsuko, HANZAWA Kazuhiko, HASEGAWA Yasuhiro

Neurosonology 26 ( 3 ) 139 - 142 2014

Language：Japanese Publisher：The Japan Academy of Neurosonology

Background and Purpose: Deep venous thrombosis (DVT) in the upper part of the body is rare, accounting for approximately 1 – 4% of all DVTs. The incidence and clinical significance of jugular vein thrombosis (JVT) were investigated in consecutive patients with acute ischemic stroke. Subjects and Methods: From December 2006 to March 2007, 71 patients (46 men, aged 70.8 ± 13.2 years) hospitalized within 48 hours after ischemic stroke or TIA onset were retrospectively examined. The presence of JVT was evaluated by ultrasonography. Patients with jugular vein catheterization were not included. Age, sex, hypertension, diabetes mellitus, hyperlipidemia, smoking status, presence of a malignant tumor, and D-dimer were assessed. Results: JVT was demonstrated in four patients (5.6%). The rate of a malignant tumor was significantly higher in patients with JVT than in those without (100% vs. 14.9%, p<0.001). The tumors were as follows: esophageal cancer (1); lung cancer (1); and uterine cervical cancer (2). The stroke subtype in three patients was Trousseau syndrome with a high D-dimer value, and that in the other patient was a lacunar stroke with a normal D-dimer value. Conclusions: Ultrasonographic evidence of JVT in patients with acute ischemic stroke could be a marker of a coincidental malignant tumor with or without Trousseau syndrome.

DOI： 10.2301/neurosonology.26.139

CiNii Article

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災害と肺塞栓症 (静脈血栓塞栓症)

榛沢和彦

心臓 46 ( 5 ) 569 - 573 2014

左側心臓弁術後の高度三尖弁閉鎖不全症再手術の問題点

名村理, 青木賢治, 岡本竹司, 上原彰史, 佐藤裕喜, 榛澤和彦, 土田正則

日本心臓血管外科学会雑誌 43 ( Supplement ) 395 - 395 2014

Simultaneous surgery for patent ductus arteriosus associated with papillary fibroelastoma

Atsushi Morishita, Hideyuki Tomioka, Seiichiro Katahira, Takeshi Hoshino, Kazuhiko Hanzawa

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20 797 - 800 2014

One-year overview of deep vein thrombosis prevalence in the ishinomaki area since the great East Japan earthquake.

Shinsaku Ueda, Kazuhiko Hanzawa, Muneichi Shibata

Annals of vascular diseases 7 ( 4 ) 365 - 8 2014

Language：English

After the Great East-Japan Earthquake, the prevalence of deep vein thrombosis (DVT) in disaster shelters in Ishinomaki (Pacific coast, Miyagi, Japan) was found much higher than that ever reported in Japan. In Ishinomaki, twelve patients were found to have pulmonary thromboembolism for one month since the earthquake and DVT was found in 10 of those patients. The calf DVT was examined using ultrasonography in the shelters (from March to July 2011) and in temporary emergency housings (from August to December 2011). Calf DVT was found in 190 of 701 evacuees. DVT prevalence was higher in the tsunami-flooded shelters (34.2%) than in that in the non-flooded shelters (19.1%). This indicated that deteriorated and crowded condition in the tsunami-flooded shelters might induce thrombogenesis in calf veins. Therefore, evacuees were recommended to leave tsunami-flooded areas. DVT prevalence in the shelters was gradually reduced, however, that was still higher in the temporary emergency housings (8.9%) than in the non-disaster area in Japan (2.2% in Yokohama city). The risk of calf DVT in the temporary emergency housings was increased because of reduced blood flow in the calf veins caused by immobility. The residents of the housings were required to be physically active to avoid calf DVT. (English translation of Jpn J Phlebol 2013; 24: 380-384).

DOI： 10.3400/avd.oa.14-00106

PubMed

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Delayed visceral and spinal cord malperfusion after axillo-bifemoral bypass for complicated acute type B aortic dissection.

Atsushi Morishita, Hideyuki Tomioka, Seiichiro Katahira, Takeshi Hoshino, Kazuhiko Hanzawa

Annals of vascular diseases 7 ( 3 ) 331 - 4 2014

Language：English

We describe a successfully treated case of acute type B aortic dissection complicated with lower extremity, visceral, and spinal cord malperfusion. To restore perfusion to both lower extremities, we performed an emergency right axillo-bifemoral bypass. Furthermore, we performed total arch replacement, including primary entry closure, because of delayed visceral organ ischemia. Unexpectedly, delayed paraplegia occurred after hospital discharge; however, the patient recovered without any neurologic sequelae after early introduction of hyperbaric oxygen therapy. Because another episode of organ malperfusion in the long term cannot be anticipated, and even though the previous organ malperfusion episode was treated successfully, close observation is mandatory for detecting clinical manifestations in combination with the availability of imaging modalities.

DOI： 10.3400/avd.cr.14-00059

PubMed

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Kommerell憩室に対するTEVARの経験

岡本竹司, 横井良彦, 佐藤裕喜, 青木賢治, 名村理, 榛澤和彦, 土田正則

日本胸部外科学会関東甲信越地方会要旨集 164th ( 164回 ) 15 - 15 2014

MDCTが有用であった大動脈基部置換術後仮性動脈瘤に対する再手術の2症例

名村理, 岡本竹司, 青木賢治, 佐藤裕喜, 榛澤和彦, 土田正則

日本血管外科学会雑誌 23 ( 2 ) 507 - 507 2014

IEに対するAVR後6年目に発症したMicrococcus roseusによるPVEの1手術例

大西遼, 名村理, 佐藤哲彰, 佐藤裕喜, 岡本竹司, 青木賢治, 榛澤和彦, 土田正則

日本胸部外科学会関東甲信越地方会要旨集 166th ( 166回 ) 16 - 16 2014

震災(災害)と静脈血栓塞栓症

榛澤和彦

International Review of Thrombosis 9 ( 4 ) 206 - 211,184 2014

Association between paroxysmal atrial fibrillation and the left atrial appendage ejection fraction during sinus rhythm in the acute stage of stroke: A transesophageal echocardiographic study International journal

Takahiro Shimizu, Tatsuro Takada, Atsuko Shimode, Yuichi Fujita, Noriko Usuki, Bunta Kato, Satoshi Takaishi, Toshikazu Hirayama, Kazuhiko Hanzawa, Yasuhiro Hasegawa

Journal of Stroke and Cerebrovascular Diseases 22 ( 8 ) 1370 - 1376 2013.11

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