Updated on 2026/03/14

写真a

 
ARAI Yuhki
 
Organization
University Medical and Dental Hospital Pediatric Surgery Assistant Professor
Title
Assistant Professor
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Degree

  • 学士 ( 2009.3   新潟大学 )

Research Areas

  • Others / Others

Research History

  • Niigata University   University Medical and Dental Hospital Pediatric Surgery   Assistant Professor

    2012.4

 

Papers

  • Identification of clinical and laboratory factors predictive of long term-native liver survival after Kasai portoenterostomy

    Takashi Kobayashi, Yoshiaki Kinoshita, Toshiyuki Ohyama, Yuhki Arai, Yu Sugai, Koichi Saito, Yu Hamasaki

    JOURNAL OF PEDIATRIC SURGERY OPEN   11   2025.7

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    DOI： 10.1016/j.yjpso.2025.100216

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  • Mesenteric Vessel-Preserving Laparoscopic Surgery for Pediatric Unicentric Castleman Disease in the Transverse Mesocolon

    Takashi Kobayashi, Yoshiaki Kinoshita, Junkichi Takemoto, Yuhki Arai, Yu Sugai, Koichi Saito, Shoichi Takano

    SURGICAL CASE REPORTS   11 ( 1 )   2025

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    DOI： 10.70352/scrj.cr.25-0307

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  • Mesenteric Vessel-Preserving Laparoscopic Surgery for Pediatric Unicentric Castleman Disease in the Transverse Mesocolon.

    Takashi Kobayashi, Yoshiaki Kinoshita, Junkichi Takemoto, Yuhki Arai, Yu Sugai, Koichi Saito, Shoichi Takano

    Surgical case reports   11 ( 1 )   2025

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    INTRODUCTION: Castleman's disease is a rare lymphoproliferative disorder. Unicentric Castleman disease (UCD) is usually benign and can be treated by complete resection. We herein report a pediatric case of UCD that occurred in the transverse mesocolon and was successfully treated with a laparoscopic approach. CASE PRESENTATION: The patient was a 10-year-old girl at the time of the surgery. She was referred to our hospital with a persistent fever of unknown origin and high C-reactive protein levels. Abdominal enhanced MRI showed a 38 × 25-mm enhanced mass in the left transverse mesocolon, and fluorodeoxyglucose PET-CT showed an abnormal accumulation in the same lesion. UCD was the most suspected diagnosis, and laparoscopic tumor resection was planned and performed. The tumor was adjacent to the inferior mesenteric vein and the left branch of the middle colic artery. There was no evidence of vascular invasion into these vessels. The feeding arteries and drainage veins were securely clipped and cut using an ultrasonic harmonic scalpel. Further dissection revealed swollen bead-like lymph nodes connected to the tumor. After all swollen lymph nodes and the tumor were isolated, they were completely resected en bloc. Colectomy was unnecessary because the main mesenteric vessels were preserved. The histopathological diagnosis was hyaline vascular-type Castleman disease. Her symptoms, such as the fever, disappeared soon after surgery. The patient was discharged on day 9 without any complications. The C-reactive protein level dropped within the normal range 2 weeks after surgery. There was no evidence of recurrence or symptoms 3 years after surgery. CONCLUSIONS: We encountered a rare case of pediatric UCD. Although only limited cases of the laparoscopic approach for pediatric UCD have been reported, we believe that the laparoscopic approach is useful for UCD in children.

    DOI： 10.70352/scrj.cr.25-0307

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  • Early and late outcomes of congenital biliary dilatation in pediatric patients

    Yoshiaki Takahashi, Takashi Kobayashi, Yoshiaki Kinoshita, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Yu Sugai, Shoichi Takano

    PEDIATRICS INTERNATIONAL   66 ( 1 )   2024.1

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    DOI： 10.1111/ped.15712

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  • Early and late outcomes of congenital biliary dilatation in pediatric patients. International journal

    Yoshiaki Takahashi, Takashi Kobayashi, Yoshiaki Kinoshita, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Yu Sugai, Shoichi Takano

    Pediatrics international : official journal of the Japan Pediatric Society   66 ( 1 )   e15712   2024

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    BACKGROUND: This study aimed to reveal the early and late postoperative complications and outcomes after surgery for congenital biliary dilatation (CBD) by reviewing cases over the past 40 years. METHODS: We retrospectively evaluated 59 patients with CBD who underwent radical surgery for complications and outcomes, based on medical records. Early complications were defined as those requiring treatment within 5 years of the initial operation. Late complications were defined as those treated more than 5 years later. RESULTS: The median age at the first surgery was 37 months. Regarding biliary reconstruction, 54 of the 59 patients (91.5%) underwent hepaticojejunostomy. Although three patients underwent cholecystoduodenostomy and one patient underwent hepaticoduodenostomy, all were converted to hepaticojejunostomy after a median of 12.5 years. One patient developed synchronous biliary carcinoma and underwent pancreaticoduodenectomy. Early complications occurred in seven patients with 10 events (surgical site infection, n = 3 bile leakage, n = 3; ileus, n = 3; bile duct obstruction, n = 1 and intussusception, n = 1). Late complications occurred in nine patients with 12 events (ileus, n = 3; anastomotic stricture, n = 3; hepatolithiasis, n = 3; asynchronous biliary carcinoma, n = 2; pancreatolithiasis, n = 1). Two of the three patients with hepatolithiasis underwent hepatectomy refractory to the endoscopic approach. Two patients developed asynchronous biliary carcinoma at 34 and 13 years after last operation; both ultimately died of the carcinoma. Only 35 patients (61.4%) underwent a follow-up examination. A total of 11 female patients (45.8%) eventually married, and all successfully gave birth. CONCLUSION: Although the long-term prognosis is excellent with complete cyst excision and hepaticojejunostomy, we emphasize the importance of long-term follow-up.

    DOI： 10.1111/ped.15712

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  • 急性腹症で発症し男性化徴候を契機に診断された副腎皮質癌の1例

    高野 祥一, 木下 義晶, 小林 隆, 高橋 良彰, 荒井 勇樹, 大山 俊之, 横田 直樹, 菅井 佑, 細貝 亮介, 近藤 修平

    日本小児外科学会雑誌   59 ( 5 )   892 - 898   2023.8

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  • A rare case of pyosalpinx in adolescent girl with Hirschsprung's disease who underwent transvaginal ultrasound-guided drainage

    Yu Sugai, Yoshiaki Kinoshita, Takashi Kobayashi, Yoshiaki Takahashi, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Shoichi Takano, Akiko Kobayashi

    SURGICAL CASE REPORTS   9 ( 1 )   2023.5

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    DOI： 10.1186/s40792-023-01657-0

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  • A rare case of pyosalpinx in adolescent girl with Hirschsprung's disease who underwent transvaginal ultrasound-guided drainage.

    Yu Sugai, Yoshiaki Kinoshita, Takashi Kobayashi, Yoshiaki Takahashi, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Shoichi Takano, Akiko Kobayashi

    Surgical case reports   9 ( 1 )   74 - 74   2023.5

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    BACKGROUND: Hydrosalpinx and pyosalpinx are rare gynecologic problems during adolescence, especially in girls without a history of sexual activity. They are even rarer in women with Hirschsprung's disease (HD). We herein report a case of pyosalpinx in an adolescent girl with HD treated by transvaginal ultrasound-guided drainage. CASE PRESENTATION: The present patient was a 12-year-old girl (weight 83 kg; height 159 cm; body mass index 32.8 kg/m2). She had undergone five laparotomies for long-segment HD by 2 years. Her menarche had occurred at 10 years. She was admitted with lower abdominal and anal pain. Computed tomography (CT), magnetic resonance imaging (MRI), and transvaginal ultrasound showed left pyosalpinx and abdominal abscess. Surgical drainage was necessary; however, she had a history of polysurgery and was severely obese, so laparotomy was considered to carry a high risk. Transvaginal ultrasound was deemed more likely to reach the abscess safely. Therefore, she was treated with transvaginal ultrasound-guided drainage by a gynecologist skilled in the procedure. She was discharged home after 52 days. One year and nine months after discharge, there was no reformation of either the abscess or pyosalpinx. CONCLUSIONS: Adolescent girls with HD are at risk of developing hydrosalpinx. Depending on the defecation status, pyosalpinx may also develop. As a less-invasive surgical treatment, transvaginal ultrasound-guided drainage can avoid laparotomy. Collaboration with a gynecologist is essential for the diagnosis and treatment of this clinical condition. Pediatric surgeons should communicate with gynecologists for such cases beginning around puberty for continuous follow-up.

    DOI： 10.1186/s40792-023-01657-0

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  • A rare case of eosinophilic gastrointestinal disorders with short bowel syndrome after strangulated bowel obstruction

    Yuhki Arai, Yoshiaki Kinoshita, Takashi Kobayashi, Yoshiaki Takahashi, Toshiyuki Ohyama, Naoki Yokota, Yu Sugai, Shoichi Takano, Yu Hamasaki, Utako Kaneko, Satoshi Kanada

    SURGICAL CASE REPORTS   8 ( 1 )   2022.9

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    DOI： 10.1186/s40792-022-01527-1

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  • A rare case of eosinophilic gastrointestinal disorders with short bowel syndrome after strangulated bowel obstruction.

    Yuhki Arai, Yoshiaki Kinoshita, Takashi Kobayashi, Yoshiaki Takahashi, Toshiyuki Ohyama, Naoki Yokota, Yu Sugai, Shoichi Takano, Yu Hamasaki, Utako Kaneko, Satoshi Kanada

    Surgical case reports   8 ( 1 )   168 - 168   2022.9

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    BACKGROUND: Short bowel syndrome (SBS) is a rare yet costly disease with an incidence rate of 3 per million people. Herein, we report a rare case of eosinophilic gastrointestinal disorders (EGIDs) with SBS after strangulated bowel obstruction. CASE PRESENTATION: A 5-year-old male had a necrotic intestine of 340 cm resected due to strangulated bowel obstruction caused by an intestinal mesenteric hiatal hernia. The length of the residual intestine was 51 cm. Bloody stools appeared 19 days postoperatively. Colonoscopy showed diffuse redness of the colonic mucosa, and pathological findings showed moderate chronic inflammatory cellular infiltration. On blood examination, the eosinophil count was > 30%. EGIDs with short bowel syndrome (SBS) were suspected. Because his symptoms did not improve with initial nutrition therapy, he was transferred to our hospital 5 months after the operation. Prednisolone was administrated at an initial dose of 1.4 mg/kg/day, 6 days after his transfer. Bloody stools disappeared after prednisolone administration. Seven months after discharge, he had no bloody stool recurrence. CONCLUSION: The risk of developing secondary EGIDs in children with SBS should be considered, and postoperative management should include attention to abdominal symptoms and elevated eosinophil counts on blood examination.

    DOI： 10.1186/s40792-022-01527-1

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  • 当院で経験した副腎皮質癌の1例

    高野 祥一, 木下 義晶, 小林 隆, 高橋 良彰, 荒井 勇樹, 大山 俊之, 横田 直樹, 菅井 佑, 廣嶋 省太, 細貝 亮介, 長崎 啓祐, 今井 千速, 近藤 修平, 大橋 瑠子, 梅津 哉

    新潟医学会雑誌   136 ( 8 )   273 - 273   2022.8

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  • The usefulness of OK-432 for the treatment of postoperative chylothorax in a low-birth-weight infant with trisomy 18. International journal

    Yoshiaki Takahashi, Yoshiaki Kinoshita, Takashi Kobayashi, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Koichi Saito, Yu Sugai, Shoichi Takano

    Clinical case reports   10 ( 5 )   e05844   2022.5

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    Chylothorax is a rare but life-threatening condition in neonates. We herein report the successful use of OK-432 for a low-birth-weight infant with trisomy 18 who developed refractory chylothorax after thoracic surgery. Increasing the concentration of OK-432 seems useful in cases with a lot of pleural effusion.

    DOI： 10.1002/ccr3.5844

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  • The usefulness of OK-432 for the treatment of postoperative chylothorax in a low-birth-weight infant with trisomy 18

    Yoshiaki Takahashi, Yoshiaki Kinoshita, Takashi Kobayashi, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Koichi Saito, Yu Sugai, Shoichi Takano

    CLINICAL CASE REPORTS   10 ( 5 )   2022.5

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    DOI： 10.1002/ccr3.5844

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  • Usefulness of Living Donor Liver Transplantation for Patients After Undergoing the Kasai Operation for Biliary Atresia. International journal

    Takashi Kobayashi, Yoshiaki Kinoshita, Yoshiaki Takahashi, Toshiyuki Ohyama, Yuhki Arai, Naoki Yokota, Koichi Saito, Kohei Miura, Hirosuke Ishikawa, Jun Sakata, Toshifumi Wakai

    Transplantation proceedings   54 ( 2 )   435 - 437   2022.3

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    BACKGROUND: Living donor liver transplantation (LDLT) has been actively performed for patients with poor clearance of jaundice after the Kasai operation for biliary atresia (BA). The present study clarified the usefulness of LDLT for BA. MATERIALS AND METHODS: Between 2000 and 2020, 24 patients (late group) underwent radical surgery for BA in our institute. The overall survival rate, native liver survival rate, and proportion of LDLT in the late group were retrospectively compared with those of 47 patients treated before 1999 (early group). P values <.05 was considered statistically significant. RESULTS: The overall survival rates at 5, 10, and 15 years were 57%, 54%, and 49%, respectively, in the early group and 100%, 100%, and 100% in the late group (P < .001). The native liver survival rates at 5, 10, and 15 years were 57%, 52%, and 39%, respectively, in the early group and 57%, 49%, and 42% (P = .993) in the late group. In the early group, LDLT was performed in 7 of 47 patients (15%), and the overall survival rate after LDLT was 71%. In the late group, LDLT was performed in 11 of 24 patients (46%), and the overall survival rate after LDLT was 100%. CONCLUSIONS: The long-term outcomes after the Kasai operation for BA have improved in recent years. There were no marked differences in long-term native liver survival before and after 2000. LDLT was actively introduced for patients with poor clearance of jaundice after the Kasai operation, and the survival rate significantly improved.

    DOI： 10.1016/j.transproceed.2021.12.027

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  • Management of refractory chylothorax in the neonatal intensive care unit: A 22-year experience

    Yoshiaki Takahashi, Yoshiaki Kinoshita, Takashi Kobayashi, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Koichi Saito, Yu Sugai, Shoichi Takano

    PEDIATRICS INTERNATIONAL   64 ( 1 )   2022.1

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    DOI： 10.1111/ped.15043

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  • Management of refractory chylothorax in the neonatal intensive care unit: A 22-year experience. International journal

    Yoshiaki Takahashi, Yoshiaki Kinoshita, Takashi Kobayashi, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Koichi Saito, Yu Sugai, Shoichi Takano

    Pediatrics international : official journal of the Japan Pediatric Society   64 ( 1 )   e15043   2022.1

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    BACKGROUND: The aim was to assess the therapeutic strategy of patients with chylothorax in a neonatal intensive care unit. METHODS: Twenty-eight infants with chylothorax were included in this study. Their clinical characteristics and outcomes were reviewed retrospectively. RESULTS: The male-to-female ratio was 1:1. The mean gestational age and birthweight were 35.1 ± 3.5 weeks and 2,692 ± 791 g, respectively. Eighteen patients were diagnosed with congenital chylothorax; chylothorax occurred postoperatively in 10 patients. Chromosomal anomalies were diagnosed in 8 patients. Six patients received surgical therapy, such as pleurodesis, thoracic duct ligation, or lymphaticovenous anastomosis. Two patients required surgery due to resistance to pleurodesis. In surgically managed patients, the daily maximum amount of pleural effusion (mL)/bodyweight (kg) ratio was significantly larger than in non-surgically managed patients: 229.0 ± 180.5 versus 59.7 ± 49.2 mL/kg. In the receiver operating characteristic analysis of the daily maximum amount of pleural effusion/bodyweight ratio, the area under the curve was 0.889 when the cut-off value was 101 mL/kg, and the sensitivity was 0.8333 and the specificity was 0.8095 (P = 0.0059). CONCLUSIONS: Pleurodesis using OK432 could become a surgical first-line therapy for chylothorax even for neonates. It was important to initiate pleurodesis for refractory chylothorax at an earlier stage. A daily chylous effusion/bodyweight ratio of >101 mL/kg was a good predictor and seemed to be a useful parameter for prompt surgical intervention.

    DOI： 10.1111/ped.15043

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  • Usefulness of the Monti-Malone procedure as a reconstruction of the antegrade continence enema procedure: a case report. International journal

    Koichi Saito, Yoshiaki Kinoshita, Yoshiaki Takahashi, Takashi Kobayashi, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota

    Surgical case reports   7 ( 1 )   112 - 112   2021.5

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    BACKGROUND: The antegrade continence enema (ACE) procedure is effective for severe constipation in patients with spina bifida and can improve quality of life (QOL). The Monti-Malone procedure (MM), which is a method of creating an enema tract from the colon, has been reported as an alternative to the ACE procedure when the appendix cannot be used. We report the usefulness of MM as a reconstruction of the antegrade continence enema procedure. CASE PRESENTATION: Our patient was a 22-year-old man with congenital spina bifida and hydrocephalus. Ventriculoperitoneal (VP) shunt surgery was performed immediately after birth, and preventative appendectomy was carried out during VP shunt repair when 4 months old. At 5 years of age, the ACE procedure using a balloon-button gastrostomy tube was performed for intractable chronic constipation. Simple management was expected, but after 17 years of age, he experienced increased stool leakage around the gastrostomy tube and his QOL declined due to difficulty in managing the ACE. Therefore, reconstruction of the ACE procedure by MM was performed. After reconstruction, the ACE performed well without any complications. The patient is currently satisfied because management of the ACE is easier than before, and his QOL has markedly improved without stool leakage and dermatitis. CONCLUSIONS: MM is less likely to cause complications and is useful as a reconstruction of the ACE procedure.

    DOI： 10.1186/s40792-021-01197-5

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  • 当施設におけるOncologic Emergency症例に対する治療戦略

    木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一, 久保 暢大, 申 将守, 笠原 靖史, 岩渕 晴子, 今村 勝, 今井 千速, 齋藤 昭彦

    日本小児救急医学会雑誌   20 ( 2 )   335 - 335   2021.5

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  • 先天性門脈体循環シャントに対するシャント離断術の経験

    小林 隆, 木下 義晶, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   57 ( 1 )   78 - 78   2021.2

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  • 右房まで到達する腫瘍栓を合併した腎芽腫diffuse anaplasiaの1例

    荒井 勇樹, 木下 義晶, 水田 耕一, 白石 修一, 今井 千速, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一, 岩渕 晴子, 今村 勝, 笠原 靖史, 申 将申, 久保 暢大

    日本小児泌尿器科学会雑誌   29 ( 2 )   185 - 185   2020.12

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  • 右房まで到達する腫瘍栓を合併した腎芽腫diffuse anaplasiaの1例

    荒井 勇樹, 木下 義晶, 水田 耕一, 白石 修一, 今井 千速, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一, 岩渕 晴子, 今村 勝, 笠原 靖史, 申 将申, 久保 暢大

    日本小児泌尿器科学会雑誌   29 ( 2 )   185 - 185   2020.12

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  • 前縦隔腫瘍の3例

    小林 隆, 木下 義晶, 荒井 勇樹, 横田 直樹, 斎藤 浩一, 申 将守, 今村 勝, 今井 千速, 土田 正則, 小川 淳

    日本小児血液・がん学会雑誌   57 ( 4 )   329 - 329   2020.10

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  • 当科における急性虫垂炎患児に対するInterval Appendectomyの適応の検討

    横田 直樹, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    日本小児外科学会雑誌   56 ( 5 )   780 - 780   2020.9

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  • 胆道閉鎖症根治術後長期成績の検討

    小林 隆, 木下 義晶, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   56 ( 5 )   691 - 691   2020.9

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  • 抜去困難となった体外式カフ付き中心静脈カテーテル3例の経験

    荒井 勇樹, 木下 義晶, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一, 岡本 竹司, 土田 正則

    日本小児外科学会雑誌   56 ( 5 )   672 - 672   2020.9

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  • 経胃瘻的空腸栄養チューブ(PEG-J)にて栄養管理を行った重症心身障害児の3例

    斎藤 浩一, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   56 ( 5 )   756 - 756   2020.9

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  • 卵巣卵黄嚢腫瘍に対する妊孕性温存治療後、残存卵巣に発症した成熟嚢胞性奇形腫摘出術前に卵子凍結を施行した1例(A case of mature teratoma in the residual ovary after fertility-sparing therapy for ovarian yolk sac tumor managed with oocyte cryopreservation followed by cystectomy)

    茅原 誠, 安達 聡介, 鈴木 久美子, 石黒 竜也, 西川 伸道, 関根 正幸, 荒井 勇樹, 木下 義晶, 榎本 隆之

    Journal of Mammalian Ova Research   37 ( 1 )   43 - 49   2020.7

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  • リンパ管奇形に対する漢方治療に関する検討

    木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   56 ( 1 )   124 - 124   2020.2

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  • 外科的切除のみにて治療を行った18トリソミーを合併した肝芽腫の1例

    横田 直樹, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    日本小児外科学会雑誌   56 ( 1 )   113 - 113   2020.2

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  • 卵巣胚細胞腫瘍の治療後数年の経過で対側卵巣に奇形腫を発症した2例

    横田 直樹, 窪田 正幸, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    日本小児外科学会雑誌   55 ( 7 )   1227 - 1227   2019.12

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  • 外傷治療 Damage control surgeryにより救命し得た交通外傷の2例

    斎藤 浩一, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   55 ( 6 )   1032 - 1033   2019.10

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  • 出生前診断された先天性胆道拡張症4例の治療経験

    荒井 勇樹, 木下 義晶, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本膵・胆管合流異常研究会プロシーディングス   42   15 - 15   2019.9

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  • 肝前性門脈圧亢進症に対する外科的治療後長期経過例の検討

    小林 隆, 窪田 正幸, 木下 義晶, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   55 ( 5 )   1012 - 1012   2019.8

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  • 当院における総排泄腔異常症における多診療科・多職種連携

    木下 義晶, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本周産期・新生児医学会雑誌   55 ( 2 )   524 - 524   2019.6

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  • 胎児期に肝門部嚢胞病変を指摘された症例の検討

    荒井 勇樹, 窪田 正幸, 木下 義晶, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本周産期・新生児医学会雑誌   55 ( 2 )   471 - 471   2019.6

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  • 肝芽腫CITA療法薬剤耐性におけるHeme oxygenese-1の関与 HepG2細胞とヒト検体を用いた検討

    小林 隆, 窪田 正幸, 木下 義晶, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   55 ( 3 )   674 - 674   2019.5

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  • Sutureless colostomyを施行した新生児症例12例の検討

    斎藤 浩一, 窪田 正幸, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   55 ( 3 )   572 - 572   2019.5

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  • 当院での化学療法目的の長期留置型中心静脈カテーテルデバイスの選択と適応

    荒井 勇樹, 窪田 正幸, 木下 義晶, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   55 ( 3 )   776 - 776   2019.5

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  • 当科における急性虫垂炎への保存的治療と緊急手術の適応に関する検討

    横田 直樹, 窪田 正幸, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    日本小児外科学会雑誌   55 ( 3 )   699 - 699   2019.5

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  • 10歳時の右付属器摘出後、左側卵巣に発生した腫瘍摘出術前に妊孕能温存目的に卵子凍結を行った1例

    茅原 誠, 安達 聡介, 関塚 智之, 鈴木 久美子, 石黒 竜也, 西川 伸道, 関根 正幸, 榎本 隆之, 高桑 好一, 荒井 勇樹, 木下 義晶, 窪田 正幸

    新潟産科婦人科学会会誌   113 ( 2 )   95 - 95   2019.2

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  • 肝間葉性過誤腫に対し硬化療法による腫瘍縮小後に腫瘍核出術を施行した1例

    斎藤 浩一, 窪田 正幸, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   55 ( 1 )   83 - 88   2019.2

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  • 十全大補湯により臀部深部に広がるクローン病肛門部病変の改善した1例

    窪田 正幸, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   55 ( 1 )   200 - 200   2019.2

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  • 有効な腸管減圧と在宅での輸液管理によりQOL改善を得た腸管不全の1例

    荒井 勇樹, 窪田 正幸, 木下 義晶, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   55 ( 1 )   190 - 190   2019.2

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  • 3qトリソミーを合併した胆道閉鎖症(III-a2-o)の1例

    小林 隆, 窪田 正幸, 木下 義晶, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   54 ( 7 )   1434 - 1434   2018.12

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  • 長期成績とTransition 総排泄腔異常症の思春期以降の機能的予後についての検討

    木下 義晶, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   54 ( 6 )   1189 - 1189   2018.10

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  • 臍上部弧状切開法により根治術を施行した新生児外科疾患の2例

    斎藤 浩一, 窪田 正幸, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹

    新潟医学会雑誌   132 ( 8-9 )   323 - 323   2018.9

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  • 胆管非拡張の膵・胆管合流異常を指摘された重症心身症女児に対して腹腔鏡下胆嚢摘出術を施行した一例

    横田 直樹, 窪田 正幸, 木下 義晶, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    日本膵・胆管合流異常研究会プロシーディングス   41   46 - 47   2018.8

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  • プロスタグランジンE1(PGE1)大量投与が原因と考えられたイレウスを呈した1例

    斎藤 浩一, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   54 ( 5 )   1165 - 1165   2018.8

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  • 男児の総排泄腔外反症の一例

    荒井 勇樹, 窪田 正幸, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本周産期・新生児医学会雑誌   54 ( 2 )   734 - 734   2018.6

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  • 当科における腹腔鏡補助下胃瘻造設術の検討

    横田 直樹, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    日本小児外科学会雑誌   54 ( 4 )   1017 - 1017   2018.6

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  • 外傷性横隔膜断裂により右胸腔内肝脱出を生じた外傷性横隔膜ヘルニアの一例

    斎藤 浩一, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   54 ( 3 )   914 - 914   2018.5

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  • 男児の総排泄腔外反症の一例

    日比野 亮信, 荒井 勇樹, 齋藤 浩一, 横田 直樹, 大山 俊之, 小林 隆, 窪田 正幸

    日本小児外科学会雑誌   54 ( 3 )   893 - 893   2018.5

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  • 両大血管右室起始症治療中に胆管結石による胆管炎を反復し胆嚢摘出術を施行した1例

    大山 俊之, 窪田 正幸, 小林 隆, 荒井 勇樹, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   54 ( 3 )   803 - 803   2018.5

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  • 胃脾間膜から発生したと考えられる腹腔内巨大リンパ管腫の一例

    横田 直樹, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    日本小児外科学会雑誌   54 ( 3 )   861 - 861   2018.5

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  • 過去20年間の当科での総排泄腔遺残症と総排泄腔外反症の臨床学的検討

    荒井 勇樹, 窪田 正幸, 小林 隆, 大山 俊之, 横田 直樹, 斎藤 浩一

    日本小児外科学会雑誌   54 ( 3 )   836 - 836   2018.5

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  • 小児の外科的悪性腫瘍、2016年登録症例の全国集計結果の報告

    田尻 達郎, 木下 義晶, 鈴木 信, 中田 光政, 北河 徳彦, 新開 統子, 金田 英秀, 東 真弓, 本多 昌平, 風間 理郎, 鈴木 完, 小松 秀吾, 荒井 勇樹, 脇坂 宗親, 近藤 知史, 高間 勇一, 栗原 将, 宗崎 良太, 日本小児外科学会悪性腫瘍委員会

    日本小児外科学会雑誌   54 ( 1 )   136 - 172   2018.1

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    DOI： 10.11164/jjsps.54.1_136

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  • 平成28年度診療報酬改定により新設された内視鏡手術3術式に関するアンケート調査報告

    廣部 誠一, 川瀬 弘一, 小高 明雄, 田中 裕次郎, 新井 真理, 荒井 勇樹, 井上 幹也, 神保 教広, 鈴木 孝明, 益子 貴行, 檜 顕成, 矢内 俊裕, 日本小児外科学会保険診療委員会

    日本小児外科学会雑誌   53 ( 5 )   1079 - 1080   2017.8

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    日本小児外科学会認定施設および教育関連施設の計154施設を対象としてアンケートを実施した。44施設から回答が得られ、内視鏡手術3術式(胸腔鏡下先天性食道閉鎖症根治手術、腹腔鏡下総胆管拡張症手術、腹腔鏡下腸重積症整復術)がなかった10施設と開創手術のみ施行していた21施設を除いて、13施設でいずれかの内視鏡手術が行われていた。内視鏡手術3術式の中では腹腔鏡下総胆管拡張症手術が施設数(10施設)と手術件数(23例)で最も多く、その疾患の手術件数に占める割合では腹腔鏡下腸重積症整復術が48%と最も高率であった。腹腔鏡下総胆管拡張症手術の手術時間は外保連試案の5時間よりも長く、その医療材料は保険適応のない自動縫合器が2個使用されていた。

    DOI： 10.11164/jjsps.53.5_1079

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  • 小児期に発見された膵内副脾に発生した類皮嚢胞(epidermoid cyst)の1例

    横田 直樹, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之

    日本小児外科学会雑誌   53 ( 1 )   89 - 93   2017.2

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  • 胆道閉鎖症の術後39年目に発生した肝細胞癌と肝内胆管癌の同時性重複癌の1例

    荒井 勇樹, 窪田 正幸, 小林 隆, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   52 ( 7 )   1303 - 1308   2016.12

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  • Staged laparotomies based on the damage control principle to treat hemodynamically unstable grade IV blunt hepatic injury in an eight-year-old girl. Reviewed International journal

    Kobayashi T, Kubota M, Arai Y, Ohyama T, Yokota N, Miura K, Ishikawa H, Soma D, Takizawa K, Sakata J, Nagahashi M, Kameyama H, Wakai T

    Surgical case reports   2 ( 1 )   134 - 134   2016.12

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    BACKGROUND: Severe blunt hepatic injury is a major cause of morbidity and mortality in pediatric patients. Damage control (DC) surgery has been reported to be useful in severely compromised children with hepatic injury. We applied such a technique in the treatment of a case of hemodynamically unstable grade IV blunt hepatic injury in an eight-year-old girl. This case is the first to use multimodal approaches including perihepatic packing, temporary closure of the abdominal wall with a plastic sheet, transarterial embolization (TAE), and planned delayed anatomical hepatic resection in a child. CASE PRESENTATION: An eight-year-old girl was run over by a motor vehicle and transferred to the emergency department of the local hospital. Her diagnoses were severe blunt hepatic injury (grade IV) with left femoral trochanteric fracture. No other organ injuries were observed. Because her hemodynamic state was stable under aggressive fluid resuscitation, she was transferred to our hospital for surgical management. On arrival at our institution about 4 h after the injury, her hemodynamic condition became unstable. Abdominal compartment syndrome also became apparent. Because her condition had deteriorated and the lethal triad of low BT, coagulopathy, and acidosis was observed, a DC treatment strategy was selected. First, emergent laparotomy was performed for gauze-packing hemostasis to control intractable bleeding from the liver bed, and the abdomen was temporarily closed with a plastic sheet with continuous negative pressure aspiration. Transarterial embolization of the posterior branch of the right hepatic artery was then carried out immediately after the operation. The lacerated right lobe of the liver was safely resected in a stable hemodynamic condition 2 days after the initial operation. Bleeding from the liver bed ceased without further need of hemostasis. She was transferred to the local hospital without any surgical complications on day 42 after admission. She had returned to her normal life by 3 months after the injury. CONCLUSION: The DC strategy was found to be effective even in a pediatric patient with hemodynamically unstable severe blunt hepatic injury. The presence of the deadly triad (hypothermia, coagulopathy, and acidosis) and abdominal compartment syndrome was an indication for DC surgery.

    DOI： 10.1186/s40792-016-0264-0

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  • 【小児NST病態栄養シリーズ:IFALD・PNACに関するトピックス】 わが国未承認薬であるω3系脂肪酸製剤の臨床使用上の注意点と課題 当院での経験をふまえて

    横田 直樹, 窪田 正幸, 小林 隆, 荒井 勇樹, 大山 俊之, 斎藤 浩一

    小児外科   48 ( 1 )   81 - 85   2016.1

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    症例1は超低出生体重、右肺低形成、中腸軸捻転術(4生日)後の女児で、6生日に静脈栄養管理(PN)を開始した。胆汁うっ滞性肝障害が進行し、77生日に人工肛門閉鎖や胆道ドレナージを施行した。術後、長期PN管理に伴い腸管不全関連肝障害(IFALD)を呈した。384生日にω3系脂肪酸製剤の投与を開始したが、6日後に肝不全と呼吸不全で死亡した。症例2は超低出生体重、小腸穿孔術(15生日)後の女児で、19生日よりPNを開始し、IFALDが進行した。ω3系脂肪酸製剤を投与し、肝機能障害が改善した。162生日の人工肛門閉鎖術後に経口摂取が可能となった。症例はMMIHSの女児で、出生時よりPNを開始した。11歳7ヵ月にMMIHSが進行し、手術を行った。経過中、長期PN管理に伴う肝機能異常が遷延し、IFALDが進行した。大豆油由来脂肪酸製剤とω3系脂肪酸製剤を併用投与したが、頭痛が出現し、ω3系脂肪酸製剤を中止した。現在、在宅PN管理を行っている。

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  • 静脈栄養管理のみにて20年以上経過した慢性特発性偽腸閉塞症例の治療関連合併症と外科治療

    荒井 勇樹, 窪田 正幸, 奥山 直樹, 仲谷 健吾, 大山 俊之, 横田 直樹

    日本小児外科学会雑誌   51 ( 2 )   218 - 223   2015.4

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  • 小児の外科的悪性腫瘍、2013年登録症例の全国集計結果の報告

    米倉 竹夫, 田尻 達郎, 伊勢 一哉, 小野 滋, 大植 孝治, 佐藤 智行, 杉藤 公信, 菱木 知郎, 平井 みさ子, 文野 誠久, 本多 昌平, 風間 理郎, 杉山 正彦, 中田 光政, 荒井 勇樹, 脇坂 宗親, 近藤 知史, 上原 秀一郎, 鬼武 美幸, 木下 義晶, 日本小児外科学会悪性腫瘍委員会

    日本小児外科学会雑誌   51 ( 1 )   96 - 132   2015.2

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    DOI： 10.11164/jjsps.51.1_96

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  • The area and attachment abnormalities of the gubernaculum in patients with undescended testes in comparison with those with retractile testes Reviewed

    Masayuki Kubota, Kengo Nakaya, Yuhki Arai, Toshiyuki Ohyama, Naoki Yokota, Yu Nagai

    PEDIATRIC SURGERY INTERNATIONAL   30 ( 11 )   1149 - 1154   2014.11

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    DOI： 10.1007/s00383-014-3597-4

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  • 著明な幽門狭窄を伴う胃十二指腸壁肥厚を契機に発見されたバーキットリンパ腫の1例

    澤野 堅太郎, 皆川 雄介, 下妻 大毅, 田中 雅人, 仁田原 康利, 楡井 淳, 小林 玲, 大橋 伯, 小野塚 淳哉, 遠藤 彦聖, 沼田 修, 田中 篤, 金田 聡, 山田 聡志, 窪田 正幸, 荒井 勇樹, 仲谷 健吾, 横田 直樹, 高橋 みのり, 小川 淳

    長岡赤十字病院医学雑誌   27 ( 1 )   39 - 42   2014.9

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    Language：Japanese   Publisher：長岡赤十字病院  

    症例は11歳男児で、3週間前から週に3、4回の嘔吐、食欲低下を認め、水分を数口摂る程度となった。血液検査、尿検査、腹部CTを施行されたが異常は指摘されず、制吐剤、整腸剤を処方された。入院4日前から腹痛が出現し、改善しないため、精査、加療のため入院した。体温36.0℃、脈拍66回/分、呼吸音・心音異常なく、腹部平坦軟、腸蠕動減弱、鼠径部リンパ節は触知しなかった。肝逸脱酵素、胆道系酵素の軽度上昇、BUNの上昇を認めた。ウイルス性腸炎を疑い、補液などの対症療法を開始した。腹部エコーで胃前庭部〜十二指腸球部に著明な壁肥厚を認めた。肝内胆管拡張や胆道閉塞は認めなかった。胃十二指腸潰瘍に伴う幽門狭窄を疑い、腹部造影CTを行い、エコー所見の他に十二指腸潰瘍、幽門狭窄を認めた。膀胱直腸窩に膿瘍を疑う液体貯留を認めた。経過中、強い腹痛は認めなかったが画像所見から穿孔性消化性潰瘍とそれに伴う腹膜炎、膀胱直腸窩膿瘍と考えられた。内視鏡による評価や生検も必要と考えられたが、胃前庭部〜十二指腸球部にかけての著明な壁肥厚は強い炎症によると判断し、絶食後、ドリペネム、プロトンポンプインヒビターで治療し、炎症軽減後、上部消化管内視鏡を行った。CTで胃の壁肥厚、肝内胆管拡張を認め、閉塞性黄疸の所見があり、症状の改善はみられず腫瘍性疾患が考えられた。診断のため生検が必要と考え、12日目に転院した。

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  • 乳児期に消化管穿孔で発症し牛乳アレルギーが疑われた1例

    仲谷 健吾, 窪田 正幸, 奥山 直樹, 小林 久美子, 佐藤 佳奈子, 荒井 勇樹, 大山 俊之

    日本小児外科学会雑誌   49 ( 2 )   231 - 235   2013.4

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  • Risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts Reviewed

    Taku Ohashi, Toshifumi Wakai, Masayuki Kubota, Yasunobu Matsuda, Yuhki Arai, Toshiyuki Ohyama, Kengo Nakaya, Naoki Okuyama, Jun Sakata, Yoshio Shirai, Yoichi Ajioka

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   28 ( 2 )   243 - 247   2013.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/j.1440-1746.2012.07260.x

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  • Risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts. Reviewed

    Ohashi Taku, Wakai Toshifumi, Kubota Masayuki, Matsuda Yasunobu, Arai Yuhki, Ohyama Toshiyuki, Nakaya Kengo, Okuyama Naoki, Sakata Jun, Shirai Yoshio, Ajioka Yoichi

    J Gastroenterol Hepatol   28 ( 2 )   243 - 247   2013.2

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    Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND AND AIM: The aim of this study was to elucidate the risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts. METHODS: A retrospective analysis of 94 patients who had undergone cyst excision for congenital choledochal cysts was conducted. The median age at the time of cyst excision and median follow-up time after cyst excision were 7 years and 181 months, respectively. RESULTS: Biliary tract cancer developed in four patients at 13, 15, 23, and 32 years after cyst excision. The cumulative incidences of biliary tract cancer at 15, 20, and 25 years after cyst excision were 1.6%, 3.9%, and 11.3%, respectively. The sites of biliary tract cancer were the intrahepatic (n = 2), hilar (n = 1), and intrapancreatic (n = 1) bile ducts. Of the four patients with biliary tract cancer after cyst excision, three patients underwent surgical resection and one patient received chemo-radiotherapy. The overall cumulative survival rates after treatment in the four patients with biliary tract cancer were 50% at 2 years and 25% at 3 years, with a median survival time of 15 months. CONCLUSIONS: The risk of subsequent biliary malignancy in pat

    DOI： 10.1111/j.1440-1746.2012.07260.x

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  • Tracheoplasty using a metallic fusiform centrally-doubled coiled stent for a major tracheal defect in rabbits Reviewed

    Masayuki Kubota, Toshifumi Wakai, Naoki Okuyama, Kumiko Kobayashi, Kanako Sato, Kengo Nakaya, Yuhki Arai, Toshiyuki Ohyama

    JOURNAL OF PEDIATRIC SURGERY   47 ( 12 )   2234 - 2238   2012.12

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jpedsurg.2012.09.012

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  • PO-100 小児の異物誤飲(小児救急4,ポスターセッション,病気の子供達に笑顔 小児外科に夢そして革新を,第47回 日本小児外科学会学術集会)

    荒井 勇樹, 大滝 雅博

    日本小児外科学会雑誌   46 ( 3 )   648 - 648   2010

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    Language：Japanese   Publisher：特定非営利活動法人 日本小児外科学会  

    DOI： 10.11164/jjsps.46.3_648_2

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MISC

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Research Projects

  • 視野測定装置の行動解析による超音波ガイド下中心静脈カテーテル挿入の新規技術開発

    Grant number：24K13360

    2024.4 - 2027.3

    System name：科学研究費助成事業

    Research category：基盤研究(C)

    Awarding organization：日本学術振興会

    荒井 勇樹, 木下 義晶

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    Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）

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  • Elucidation of the signal expression mechanism in the mTOR cell and development of the rapamycin treatment in the hepatoblastoma

    Grant number：16K11341

    2016.4 - 2019.3

    System name：Grants-in-Aid for Scientific Research

    Research category：Grant-in-Aid for Scientific Research (C)

    Awarding organization：Japan Society for the Promotion of Science

    Arai Yuhki

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    Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）

    After examining 27 hepatoblastoma cases in our hospital for the past 30 years, I compared the clinical data such as the prognosis and the biological malignancy with the result of the immunostaining due to the mTOR (Ser2448) antibody of the preparation, and the tendency that a value of provided Labeling index related to was recognized by a malignancy and immunostaining. It did not lead to number of cases before finding enough significant difference, but, in the expression of hepatoblastoma, it is thought that PI3K/Akt/mTOR course participates, and the possibility that the drug which inhibited mTOR signaling course could become the therapeutic agent of the hepatoblastoma in the future was suggested.

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Teaching Experience

  • 小児外科学

    2018
    Institution name：新潟大学

  • 疾病の成因と治療Ⅱ

    2017
    -
    2021
    Institution name：新潟大学