Updated on 2024/05/05

写真a

 
MITSUHASHI Daijiyu
 
Organization
University Medical and Dental Hospital Neurosurgery Assistant Professor
Title
Assistant Professor
External link

Degree

  • 学士　(医歯薬学) ( 2008.3   新潟大学 )

Research History

  • Niigata University   Neurosurgery, University Medical and Dental Hospital   Assistant Professor

    2023.1

  • Niigata University   University Medical and Dental Hospital Neurosurgery   Specially Appointed Assistant Professor

    2018.4 - 2019.3

 

Papers

  • Unique image findings around “kissing” distal anterior cerebral artery aneurysms in addition to perianeurysmal edema: A case report

    Daiju Mitsuhashi, Takuya Okada, Keisuke Sato, Naoki Yajima, Toyotaka Aiba

    Surgical Neurology International   14   181 - 181   2023.5

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    Publishing type：Research paper (scientific journal)   Publisher：Scientific Scholar  

    Background:

    Some aneurysms cause edema formation in the surrounding brain parenchyma and are thought to reflect various phenomena occurring in the aneurysm. Some authors highlighted perianeurysmal edema (PAE) as a finding that indicates higher risk of rupture of the aneurysm. On the other hand, there are no reports of image changes in the surrounding brain parenchyma of aneurysm other than edema formation.

    Case Description:

    We describe a 63-year-old man with unique signal change in the surrounding brain parenchyma of “kissing” distal anterior cerebral artery aneurysms completely different from PAE. The large and partially thrombosed aneurysm presented well-defined signal change surrounding brain parenchyma in addition to PAE. Intraoperative findings revealed the signal change as a space of retaining serous fluid. Drain the fluid and clipping was made for the both anterior cerebral artery aneurysms. The postoperative course was uneventful and his headache was improved the day after the surgery. The perianeurysmal signal change was also disappeared immediately after the surgery except for the PAE.

    Conclusion:

    This case demonstrates a rare phenomenon of signal change around the aneurysm, and there is a possibility that the unique finding exists as an early manifestation of intracerebral hematoma associated with aneurysm rupture.

    DOI： 10.25259/sni_109_2023

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    Other Link： http://surgicalneurologyint.com/surgicalint-articles/unique-image-findings-around-kissing-distal-anterior-cerebral-artery-aneurysms-in-addition-to-perianeurysmal-edema-a-case-report/

Research Projects

  • Establishment of new intraoperative imaging using flavoprotein autofluorescence

    Grant number：18K16579

    2018.4 - 2022.3

    System name：Grants-in-Aid for Scientific Research

    Research category：Grant-in-Aid for Early-Career Scientists

    Awarding organization：Japan Society for the Promotion of Science

    Mitsuhashi Daiku

    　 More details

    Grant amount：\1950000 （ Direct Cost: \1500000 、 Indirect Cost：\450000 ）

    To develop an innovative brain mapping and neuromonitoring method during neurosurgery, the authors set
    out to establish intraoperative flavoprotein fluorescence imaging (iFFI) to directly visualize cortical activations in human brain. The significance of iFFI was analyzed by comparison with intraoperative perfusion-dependent imaging (iPDI),which is considered the conventional optical imaging. Signals acquired by iFFI exhibited biphasic spatiotemporal changes consisting of an early positive signal peak (F1) and a delayed negative signal peak (F2). In contrast, iPDI signals exhibited only 1 negative peak (P1) that was significantly delayed compared to F1. This is the first report in humans of successful intraoperative visualization of cortical activations using iFFI, which showed rapid evoked cortical activity prior to perfusion-dependent signal changes.

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