Updated on 2025/10/25

写真a

 
KOGA Hiroshi
 
Organization
Graduate School of Medical and Dental Sciences Specially Appointed Associate Professor
Title
Specially Appointed Associate Professor
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Degree

  • 博士(医学) ( 2018.3 )

Research Areas

  • Life Science / Orthopedics

Research History

  • Niigata University   Graduate School of Medical and Dental Sciences   Specially Appointed Associate Professor

    2018.10

Professional Memberships

  • Japanese Pediatric Orthopaedic Association

    2019

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  • Japanese Association on Sarcopenia and Frailty

    2019

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  • Japanese Society of Clinical Biomechanics

    2016

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  • Tohoku Society for Orthopaedic and Traumatology

    2012

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  • Japanese Society of Clinical Sports Medicine

    2012

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  • Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine

    2012

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  • Niigata Society of Orthopaedic Surgery

    2007

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  • Japanese Orthopaedic Association

    2007

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Committee Memberships

  •   小千谷市健康こいこいポイント事業実行委員会  

    2019   

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    Committee type:Municipal

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Papers

  • 変形性膝関節症X線進行度の経時的大腿骨・脛骨関節面線角度変化に関する疫学要因の検討 進行期における膝伸展筋力の重要性

    田中 正栄, 古賀 寛, 渡邉 博史, 森清 友亮, 西野 勝敏, 望月 友晴, 大森 豪, 古賀 良生

    臨床バイオメカニクス   45   54 - 59   2024.10

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  • 変形性膝関節症におけるX線進行度評価の経時的角度変化 内反変化の初期に脛骨骨軸傾斜角,後期に関節開き角が寄与

    渡邉 博史, 田中 正栄, 森 隆裕, 古賀 寛, 望月 友晴, 大森 豪, 森清 友亮, 古賀 良生

    臨床バイオメカニクス   45   1 - 8   2024.10

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  • 地域医療 新潟県の乳児股関節検診

    古賀 寛, 村上 玲子, 森清 友亮, 川島 寛之

    新潟県医師会報   ( 893 )   14 - 17   2024.8

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  • 地域医療 新潟県の乳児股関節検診

    古賀 寛, 村上 玲子, 森清 友亮, 川島 寛之

    新潟県医師会報   ( 893 )   14 - 17   2024.8

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  • Association between three-dimensional gait kinematics and joint-line inclination in osteoarthritic knees compared with normal knees: An epidemiological study. International journal

    Fangzhou Chi, Tomoharu Mochizuki, Hiroshi Koga, Go Omori, Katsutoshi Nishino, Shigeru Takagi, Yoshio Koga, Hiroyuki Kawashima

    Journal of experimental orthopaedics   11 ( 3 )   e12040   2024.7

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    PURPOSE: No report has proven how tibial and femoral joint-line inclinations affect thigh and shank motion, respectively, according to Kellgren-Lawrence grade in motion analysis with a sufficient sample size. Therefore, this study aimed to evaluate the motion of the thigh and shank individually from the ground and the relative motion between bones in a large-sample motion analysis to determine the differences between normal and osteoarthritic knees and examine the effects of tibial and femoral joint-line inclination on motion according to osteoarthritis (OA) grade. METHODS: Of 459 participants with healthy knees and varus knee OA undergoing three-dimensional gait analysis, 383 (218 females and 165 males) with an average age of 68 ± 13 years were selected. Gait analysis was performed using a motion-capture system. The six degrees of freedom motion parameters of the knee in the Grood and world coordinate systems and the joint-line inclination in the standing radiographs were measured. RESULTS: Osteoarthritic knees demonstrated a relative motion different from that of normal knees, with responsibility for the thigh in the sagittal and rotational planes and the thigh and shank in the coronal plane. The involvement of joint-line inclination in motion was mainly on the tibial side, and the effect was minimal in normal knees. CONCLUSIONS: The details of the relative motion of both the thigh and shank can be clarified by analysing individual motions to determine the responsible part. The tibial joint-line affected knee motion: however, the effect was minimal in normal knees. This finding implies that if physical ability can be improved, the negative effects of deformity in osteoarthritic knees may be compensated for. LEVEL OF EVIDENCE: Level Ⅱ.

    DOI: 10.1002/jeo2.12040

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  • Accuracy of a portable lower-limb muscle strength measuring device with a training function.

    Atsushi Nawata, Hiroshi Koga, Rieko Sasaki, Hiroshi Watanabe, Go Omori, Yoshio Koga, Hiroyuki Kawashima

    Journal of physical therapy science   36 ( 6 )   343 - 351   2024.6

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    [Purpose] Quadriceps muscle strength is essential for daily living activities. Therefore, we developed a compact and simple lower limb muscle strength measuring device (LocomoScan [LCS]). This study aimed to compare LCS with other instruments to analyze its simplicity, reproducibility, and accuracy. [Participants and Methods] One hundred and four healthy university students (56 males and 48 females) were included in the study. The knee extension force was measured using LCS, and the knee extension torque was measured using other devices (Cybex). In addition, lower leg muscle mass was measured using a body composition meter. The reproducibility of LCS and the correlation between the knee extension torque and lower leg muscle mass were evaluated. [Results] The measurement reproducibility of LCS was significantly higher. The knee extension force confirmed the proportional relative reliability of Cybex with knee extension torque. A relationship between knee extension force and lower limb muscle mass was also observed, indicating that muscle mass cannot be estimated as muscle strength. [Conclusion] The high reproducibility of the knee extension force measurement using LCS demonstrates its potential as a portable alternative instrument for muscle strength measurement in clinical practice. Therefore, LCS device is a simple and effective tool for assessing muscle strength.

    DOI: 10.1589/jpts.36.343

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  • 血友病性関節症に対する人工膝関節置換術の治療経験

    谷藤 理, 望月 友晴, 古賀 寛, 前田 圭祐, 川島 寛之

    日本人工関節学会誌   53   91 - 92   2023.12

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  • The Matsudai Knee Osteoarthritis Survey showed the longitudinal changes of knee phenotypes in alignment and structure during 23-28 years. International journal

    Yasuyuki Tomiyama, Tomoharu Mochizuki, Hiroshi Koga, Go Omori, Yoshio Koga, Osamu Tanifuji, Katsutoshi Nishino, Kazuo Endo, Naoto Endo, Hiroyuki Kawashima

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA   31 ( 11 )   5034 - 5047   2023.11

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    PURPOSE: The longitudinal changes in alignment and structure, including the joint line and cortical bone thickness (CBT) of the femur and tibia, and knee phenotype in patients with knee osteoarthritis (OA) remain unknown. The aim of this retrospective study was to clarify the longitudinal changes in matched healthy subjects. METHODS: The follow-up Matsudai Knee Osteoarthritis Survey was administered between 23 and 28 years. This study included 285 healthy knees from 235 females with an average age of 53 ± 6 years at baseline. The non-OA individuals, with an average age of 79 ± 4 years, were divided into three groups at baseline according to their follow-up radiographic results [the non-OA (n = 52), early OA (n = 131), and advanced OA groups (n = 102)]. Changes in alignment, joint line, CBT, and knee phenotype were assessed at baseline and at follow-up using standing anteroposterior radiographs. RESULTS: This study showed significant varus changes in the alignment (p < 0.001) and tibial and femoral joint line parameters (p < 0.05) in the OA group. Decreased CBT and increased mediolateral CBT ratios were observed in all groups (p < 0.001). The knee phenotypes in the OA groups were changed to varus angles, especially in the alignment and tibial joint line. CONCLUSIONS: The longitudinal changes of knee phenotypes in alignment and structure (CBT and joint line) from baseline to follow-up were shown in the OA groups. In addition, alignment and tibial structural factors at baseline are useful in predicting the incidence of knee OA in daily practice. LEVELS OF EVIDENCE: III.

    DOI: 10.1007/s00167-023-07554-1

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  • 変形性膝関節症の診療・研究の最前線 脛骨内側関節面冠状面傾斜は冠状面の歩行動作に影響を与える

    望月 友晴, 谷藤 理, 古賀 寛, 高木 繁, 大森 豪, 古賀 良生, 川島 寛之

    日本整形外科学会雑誌   97 ( 8 )   S1786 - S1786   2023.8

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  • 松代膝検診における三次元歩行解析を用いたスラスト現象の分析

    望月 友晴, 谷藤 理, 古賀 寛, 大森 豪, 西野 勝敏, 土方 啓生, 前田 圭祐, 古賀 良生, 川島 寛之

    日本整形外科学会雑誌   97 ( 3 )   S865 - S865   2023.3

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  • 変形性膝関節症におけるX線進行度評価の経年的角度変化についての検討 松代膝検診の縦断的疫学調査

    渡邉 博史, 田中 正栄, 西野 勝敏, 森 隆裕, 古賀 寛, 望月 友晴, 坂上 勇太, 森清 友亮, 高根沢 佑斗, 坂本 信, 田邊 裕治, 大森 豪, 古賀 良生

    臨床バイオメカニクス   43   239 - 245   2022.10

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  • 膝前後X線像による皮質骨幅測定の精度検証

    高根沢 佑斗, 森清 友亮, 坂上 勇太, 森 隆裕, 古賀 良生, 望月 友晴, 古賀 寛, 坂本 信, 小林 公一, 田邊 裕治, 佐々木 朋裕

    臨床バイオメカニクス   43   253 - 257   2022.10

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  • Normal coronal kinematics of dynamic alignment and bony positions relative to the ground in three-dimensional motion analysis during gait: A preliminary study. International journal

    Yasuyuki Tomiyama, Tomoharu Mochizuki, Osamu Tanifuji, Katsutoshi Nishino, Masaei Tanaka, Go Omori, Noriaki Yamamoto, Hiroshi Koga, Yoshio Koga, Hiroyuki Kawashima

    Bio-medical materials and engineering   2022.6

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    BACKGROUND: During gait, healthy knee coronal kinematics of each bony axis and lower extremity alignment are important because they could be useful as reference data for several surgeries and provide clarification of the etiology of diseases around the knee in healthy participants; however, it remains unknown. OBJECTIVE: The objective of this study was to clarify the kinematics of lower extremity alignment and the bony axes relative to the ground during gait, focused on the coronal plane, in healthy individuals by applying our unique three-dimensional (3D) motion analysis. METHODS: The study included 21 healthy individuals, including 9 healthy females and 12 healthy males with an average age of 36 ± 17 years. Knee kinematics were calculated in a gait analysis by combining the data from a motion-capture system and a 3D lower-extremity alignment assessment system on biplanar long-leg radiographs by using a 3D-2D registration technique. The main kinematic parameters were the dynamic position change relative to the ground, applying the femoral anatomical axis (FAA), tibial anatomical axis (TAA), and dynamic alignment in the coronal plane during the stance phase of gait. RESULTS: The average changes in FAA, TAA, and dynamic varus alignment were 3.7° ± 1.2°, 3.5° ± 0.8°, and 3.0° ± 1.2°, respectively. The TAA tilted laterally during the loading response and a plateau area appeared afterwards; the FAA gradually inclined laterally until the terminal stance phase, and the dynamic alignment showed varus angular change during the loading response. CONCLUSIONS: The tibia and femur were found to change approximately 2-5° of the position of the bony axes relative to the ground. In terms of clinical relevance, our findings can be used to clarify the etiology of diseases around the knee joint and as reference data for surgeries.

    DOI: 10.3233/BME-211383

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  • The coronal inclination of the medial tibial plateau affects coronal gait kinematics for varus osteoarthritic knees. International journal

    Tomoharu Mochizuki, Osamu Tanifuji, Go Omori, Katsutoshi Nishino, Masaei Tanaka, Hiroshi Koga, Takahiro Mori, Yoshio Koga, Hiroyuki Kawashima

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA   2022.6

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    PURPOSE: This study aims to (1) measure the kinematics of lower extremity alignment and the bony position relative to the ground during walking, focusing on the coronal plane, and (2) determine the correlation between the kinematics and coronal inclination of the medial tibial plateau (coronal inclination) for healthy and varus knee osteoarthritis (OA). METHODS: In this study, 43 women (non-OA, 9 knees; early OA, 13 knees; advanced OA, 21 knees; mean age 58 ± 17 years) were examined. The knee phenotypes in varus knee OA were varied. Three-dimensional (3D) knee kinematics were calculated in gait analysis by combining the motion capture system and the 3D lower extremity alignment assessment system via biplanar long-leg X-rays, applying the 3D-2D registration technique. The main parameters were the kinematics of the bony axes relative to the ground in the coronal plane during the stance phase of the gait. The differences in overall kinematics were assessed using repeated measures ANOVA with Tukey's post hoc test. The association between kinematic parameters and coronal inclination was evaluated by multiple linear regression after univariate analysis. RESULTS: The tibia tilted laterally during the loading response, and a plateau area subsequently appeared until the terminal stance phase, whereas the femur slowly tilted laterally until the terminal stance phase. The dynamic alignment showed a relatively large varus angular change during the loading response in all groups. The trend of motion was similar among all groups (p = n.s.), although to varying degrees. The coronal inclination was the more dominant factor than the Kellgren-Lawrence (K-L) grades (β =  - 0.423, p = 0.005) when the change in dynamic alignment was determined. CONCLUSIONS: The TAA plateau area after the loading response implies that the tibial articular surface may become horizontal. The femur slowly tilted laterally until the terminal stance phase in response to the tibial motion. Consequently, the dynamic alignment showed a varus angular change, in which coronal MCT was more involved than K-L grades.

    DOI: 10.1007/s00167-022-07019-x

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  • 当院におけるAPS(Autologous Protein Solution)投与の実際と短期成績

    添野 竜也, 望月 友晴, 谷藤 理, 土方 啓生, 古賀 寛

    新潟整形外科研究会会誌   37 ( 1 )   29 - 34   2021.12

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  • 本県における自家培養軟骨移植術(JACC)の治療経験

    谷藤 理, 望月 友晴, 古賀 寛, 添野 竜也, 土方 啓生, 川島 寛之

    新潟整形外科研究会会誌   37 ( 1 )   55 - 55   2021.12

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  • APS(autologous protein solution)投与の実際と短期成績

    添野 竜也, 望月 友晴, 谷藤 理, 土方 啓生, 川島 寛之, 古賀 寛

    新潟整形外科研究会会誌   37 ( 1 )   56 - 56   2021.12

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  • 成長期外側円板状半月板術後の外側半月板中節逸脱に影響を及ぼす因子の検討 多施設共同研究

    望月 友晴, 谷藤 理, 添野 竜也, 土方 啓生, 川島 寛之, 古賀 寛

    新潟整形外科研究会会誌   37 ( 1 )   57 - 57   2021.12

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  • 当院におけるAPS(Autologous Protein Solution)投与の実際と短期成績

    添野 竜也, 望月 友晴, 谷藤 理, 土方 啓生, 古賀 寛

    新潟整形外科研究会会誌   37 ( 1 )   29 - 34   2021.12

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  • 膝前後単純X画像における変形性膝関節症進行度の定量的評価システムの開発と信頼性の検討

    森 隆裕, 坂上 勇太, 望月 友晴, 古賀 良生, 森清 友亮, 古賀 寛, 大森 豪, 小林 公一, 坂本 信, 田邊 裕治

    臨床バイオメカニクス   42   39 - 43   2021.10

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  • 変形性膝関節症X線定量評価に基づく進行予測のための疫学要因の検討

    渡邉 博史, 田中 正栄, 西野 勝敏, 大森 豪, 古賀 寛, 望月 友晴, 森清 友亮, 坂上 勇太, 古賀 良生

    臨床バイオメカニクス   42   33 - 38   2021.10

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  • 変形性膝関節症X線定量評価に基づく進行予測のための疫学要因の検討

    渡邉 博史, 田中 正栄, 西野 勝敏, 大森 豪, 古賀 寛, 望月 友晴, 森清 友亮, 坂上 勇太, 古賀 良生

    臨床バイオメカニクス   42   33 - 38   2021.10

  • 膝前後単純X画像における変形性膝関節症進行度の定量的評価システムの開発と信頼性の検討

    森 隆裕, 坂上 勇太, 望月 友晴, 古賀 良生, 森清 友亮, 古賀 寛, 大森 豪, 小林 公一, 坂本 信, 田邊 裕治

    臨床バイオメカニクス   42   39 - 43   2021.10

  • Association of isometric quadriceps strength with stride and knee kinematics during gait in community dwelling adults with normal knee or early radiographic knee osteoarthritis. International journal

    Katsutoshi Nishino, Hiroshi Koga, Yoshio Koga, Masaei Tanaka, Atsushi Nawata, Kazuo Endoh, Masaaki Arakawa, Go Omori

    Clinical biomechanics (Bristol, Avon)   84   105325 - 105325   2021.4

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    BACKGROUND: Identifying indicators of early knee osteoarthritis is important for preventing the onset and/or progression of the disease. Although low quadriceps strength and changes in stride and knee kinematics during gait have been suggested as possible indicators, their relevance and relationships have not been fully examined. This study aimed to analyze the association of quadriceps strength with stride and knee kinematics during gait in adults with normal knee or early knee osteoarthritis. METHODS: A total of 881 knees from 474 community dwelling adults (238 males and 236 females) were included. Radiographic images of the knee in standing position were obtained, and grading of knee osteoarthritis was classified. Isometric quadriceps strength was measured using a force detector device. Three-dimensional knee kinematics during gait was obtained by a motion capture system. Sex-based difference of quadriceps strength, stride and knee kinematics during gait was evaluated by multiple comparison among grades by sex and multiple regression of quadriceps strength was analyzed by stride and knee kinematics during gait. FINDINGS: Stride length and quadriceps strength were significantly reduced with higher grade in both sexes, and changes in knee kinematics during gait differed by sex from early knee osteoarthritis. Quadriceps strength in both sexes was significantly correlated with changes in stride length and knee kinematics during gait. INTERPRETATION: Improving quadriceps strength in early knee osteoarthritis was related with maintaining gait ability and restraining abnormal knee kinematics during gait. This may help to develop clinical approaches to prevent the onset and/or progression of knee osteoarthritis.

    DOI: 10.1016/j.clinbiomech.2021.105325

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  • スラストに影響を与える要因 脛骨近位内側関節面傾斜はスラスト現象に寄与する

    嶋 俊郎, 望月 友晴, 古賀 良生, 古賀 寛, 谷藤 理, 大森 豪, 川島 寛之

    日本整形外科学会雑誌   95 ( 3 )   S614 - S614   2021.3

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  • 健常高齢者における大腿骨骨幹部骨皮質幅と彎曲の関係

    染矢 圭一郎, 望月 友晴, 前田 圭祐, 穂苅 翔, 勝見 亮太, 古賀 寛, 谷藤 理, 古賀 良生, 川島 寛之

    日本整形外科学会雑誌   95 ( 3 )   S875 - S875   2021.3

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  • New evaluation indices for rotational knee angles in standing anteroposterior knee radiographs. International journal

    Takahiro Mori, Tomoharu Mochizuki, Yoshio Koga, Hiroshi Koga, Koichi Kobayashi, Ryota Katsumi, Makoto Sakamoto, Go Omori, Yuji Tanabe

    Bio-medical materials and engineering   32 ( 2 )   85 - 99   2021

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    BACKGROUND: Identifying the time course of rotational knee alignment is crucial for elucidating the etiology in knee osteoarthritis. OBJECTIVE: The aim of this study was to propose new rotational indices for calculating the change in relative rotational angles between the femur and tibia in standing anteroposterior (AP) radiographs. METHODS: Forty healthy elderly volunteers (20 women and 20 men; mean age, 70 ± 6 years) were assessed. The evaluation parameters were as follows: (1) femoral rotational index: the distance between the sphere center of the medial posterior femoral condyle and the lateral edge of the patella, and (2) tibial rotational index: the distance between the medial eminence of the tibia and the lateral edge of the fibula head. The indices were standardized by the diameter of the sphere of the medial posterior femoral condyle. This study (1) identified the relationship between changes in rotational indices and the simulated rotational knee angles in the standing position, (2) proposed a regression equation for the change in relative rotational angles between the femur and tibia in standing AP radiographs, and (3) verified the accuracy of the regression equation. RESULTS: The rotational indices increased in direct proportion to simulated rotational knee angles (femoral index: r > 0.9,p < 0.0001; tibial index: r > 0.9, p < 0.0001). Based on the results, the regression equation with the accuracy of 0.45 ± 0.26° was determined. CONCLUSIONS: The proposed regression equations can potentially predict the change in relative rotational angles between the femur and tibia in a pair of standing AP radiographs taken at different dates in longitudinal studies.

    DOI: 10.3233/BME-201138

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  • The medial inclination of the proximal tibia is associated with the external knee adduction moment in advanced varus knee osteoarthritis. International journal

    Tomoharu Mochizuki, Go Omori, Katsutoshi Nishino, Masaei Tanaka, Osamu Tanifuji, Hiroshi Koga, Takahiro Mori, Yoshio Koga, Hiroyuki Kawashima

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA   30 ( 2 )   574 - 583   2020.10

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    PURPOSE: Whether the inclined articular surface on the medial proximal tibia and the external knee adduction moment (KAM) correlate remains unclear. The hypothesis was that a steeper inclined articular surface correlated with a larger KAM in advanced knee osteoarthritis (OA). METHODS: A total of 44 females (non-OA, 9 knees; early OA, 14 knees; advanced OA, 21 knees; mean age, 58 ± 16 years) were examined. Three-dimensional (3D) assessment was used on biplanar long-leg radiographs and 3D bone models using a 3D to 2D image registration technique. The approximation plane in the proximal tibia was determined using the least-square method. The joint moments were mathematically calculated in a gait analysis, applying a motion capture system and force plates. The main evaluation parameters were the femorotibial angle (FTA), the coronal inclination of the approximation plane in the medial proximal tibia (coronal inclination), and internal knee joint moments. The KAM means the external moments balanced with the internal knee abduction moments. RESULTS: The advanced OA showed a larger internal abduction moment (p = 0.017) at the loading response than the other groups. The larger FTA and steeper coronal inclination correlated with the larger internal abduction moment (FTA, p < 0.001; coronal inclination, p = 0.003) at the loading response. CONCLUSIONS: As the clinical relevance, the association among the coronal inclination of the medial proximal tibia, lower extremity alignment, and KAM is one of the key factors to help better understand the etiology of knee OA. LEVEL OF EVIDENCE: III.

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  • Cortical thickness of the tibial diaphysis reveals age- and sex-related characteristics between non-obese healthy young and elderly subjects depending on the tibial regions. International journal

    Keisuke Maeda, Tomoharu Mochizuki, Koichi Kobayashi, Osamu Tanifuji, Keiichiro Someya, Sho Hokari, Ryota Katsumi, Yusuke Morise, Hiroshi Koga, Makoto Sakamoto, Yoshio Koga, Hiroyuki Kawashima

    Journal of experimental orthopaedics   7 ( 1 )   78 - 78   2020.10

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    PURPOSE: This study aimed to evaluate the age- and sex-related characteristics in cortical thickness of the tibial diaphysis between non-obese healthy young and elderly subjects as reference data. METHODS: The study investigated 31 young subjects (12 men and 19 women; mean age, 25 ± 8 years) and 54 elderly subjects (29 men and 25 women; mean age, 70 ± 6 years). Three-dimensional estimated cortical thickness of the tibial diaphysis was automatically calculated for 5000-9000 measurement points using the high-resolution cortical thickness measurement from clinical computed tomography data. In 12 assessment regions created by combining three heights (proximal, central, and distal diaphysis) and four areas of the axial plane at 90° (medial, anterior, lateral, and posterior areas) in the tibial coordinate system, the standardized thickness was assessed using the tibial length. RESULTS: As structural characteristics, there were no differences in the medial and lateral thicknesses, while the anterior thickness was greater than the posterior thickness in all groups. The sex-related difference was not shown. As an age-related difference, elderly subjects showed greater or lesser cortical thickness than the young subjects, depending on the regions of the tibia. CONCLUSIONS: Cortical thickness was different depending on sex, age, and regions in the tibia. The results of this study are of clinical relevance as reference points to clarify the causes of various pathological conditions for diseases. LEVEL OF EVIDENCE: Level 3.

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  • Articular surface of the medial proximal tibia is aligned parallel to the ground in three-dimensional space under weight-bearing conditions in healthy and varus osteoarthritic knees. International journal

    Tomoharu Mochizuki, Yoshio Koga, Takahiro Mori, Katsutoshi Nishino, Koichi Kobayashi, Osamu Tanifuji, Takashi Sato, Ryota Katsumi, Hiroshi Koga, Go Omori, Yuji Tanabe

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA   28 ( 10 )   3232 - 3239   2020.10

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    PURPOSE: To test the hypothesis that an inclined articular surface on the medial proximal tibia is aligned more parallel to the ground in three-dimensional (3D) space under weight-bearing (WB) conditions (parallel phenomenon) than under non-WB (NWB) conditions in healthy and varus osteoarthritic knees. METHODS: We examined 55 healthy knees (26 women, 29 men; mean age, 70 ± 6 years) and 108 varus osteoarthritic knees (66 women, 16 men; mean age, 74 ± 7 years). For the evaluation under WB conditions, a 3D assessment system was used on biplanar long-leg radiographs and 3D bone models using a 3D-to-2D image registration technique. In addition, the least square method was used to determine the approximation plane. The angles between the normal vector for the approximation plane of an articular surface on the medial proximal tibia and each axis of the tibial or world coordinate system were calculated. RESULTS: Morphologically, the inclination of the approximation plane was steeper in osteoarthritic knees than in healthy knees (p < 0.0001). The approximation plane was aligned more parallel to the ground under WB conditions than under NWB conditions in healthy (p < 0.0001) and osteoarthritic knees (p < 0.0001). CONCLUSIONS: The parallel phenomenon in the medial proximal tibia was confirmed for healthy and varus osteoarthritic knees. The medial proximal tibia plays an important role in the parallel phenomenon, assumingly associated with varus alignment and varus thrust. The inclination of the medial proximal tibia may become a new parameter for imaging investigations. LEVEL OF EVIDENCE: III.

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  • Windswept deformityを呈する変形性膝関節症における下肢アライメントと腸脛靱帯緊張の評価

    森清 友亮, 田中 正栄, 小林 公一, 坂本 信, 田邊 裕治, 望月 友晴, 古賀 寛, 大森 豪, 湊 泉, Wadugodapitiya Surangika, 藤原 靖, 古賀 良生

    臨床バイオメカニクス   41   115 - 119   2020.10

  • 変形性膝関節症初期変化のX線前後画像についての定量的縦断検討

    森 隆裕, 古賀 良生, 望月 友晴, 古賀 寛, 小林 公一, 大森 豪, 田邊 裕治

    臨床バイオメカニクス   41   121 - 126   2020.10

  • Age- and sex-related characteristics in cortical thickness of femoral diaphysis for young and elderly subjects.

    Keiichiro Someya, Tomoharu Mochizuki, Sho Hokari, Osamu Tanifuji, Ryota Katsumi, Hiroshi Koga, Yuki Takahashi, Koichi Kobayashi, Yusuke Morise, Makoto Sakamoto, Yoshio Koga, Naoto Endo

    Journal of bone and mineral metabolism   38 ( 4 )   533 - 543   2020.7

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    INTRODUCTION: Cortical thickness of the femoral diaphysis is assumed to be a preferred parameter in the assessment of the structural adaptation by mechanical use and biological factors. This study aimed to investigate the age- and sex-specific characteristics in cortical thickness of the femoral diaphysis between young and elderly non-obese people. MATERIALS AND METHODS: This study investigated 34 young subjects (21 men and 13 women; mean age: 27 ± 8 years) and 52 elderly subjects (29 men and 23 women; mean age: 70 ± 6 years). Three-dimensional (3D) cortical thickness of the femoral diaphysis was automatically calculated for 5000-8000 measurement points using the high-resolution cortical thickness measurement from clinical CT data. In 12 assessment regions created by combining three heights (proximal, central, and distal diaphysis) and four areas of the axial plane at 90° (medial, anterior, lateral, and posterior areas) in the femoral coordinate system, the standardized thickness was assessed using the femoral length. RESULTS: As per the trends, (1) there were no differences in medial and lateral thicknesses, while the posterior thickness was greater than the anterior thickness, (2) the thickness in men was higher than that in women, and (3) the thickness in young subjects was higher than that in elderly subjects. CONCLUSIONS: The results of this study are of clinical relevance as reference points to clarify the causes of various pathological conditions for diseases of the lower extremities.

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  • 早期変形性膝関節症の立位膝X線画像における大腿骨・脛骨間の相対的回旋変化の縦断的評価

    森 隆裕, 古賀 良生, 大森 豪, 望月 友晴, 古賀 寛, 小林 公一, プラムディタ・ジョナス・アディティヤ, 田邊 裕治

    臨床バイオメカニクス   40   107 - 111   2019.10

  • 【変形性膝関節症-病態・評価・治療】病態 大規模住民コホート研究からみた膝OAの病態

    大森 豪, 古賀 寛, 望月 友晴, 古賀 良生

    関節外科   38 ( 6 )   555 - 562   2019.6

  • Effect on inclined medial proximal tibial articulation for varus alignment in advanced knee osteoarthritis. International journal

    Tomoharu Mochizuki, Yoshio Koga, Osamu Tanifuji, Takashi Sato, Satoshi Watanabe, Hiroshi Koga, Koichi Kobayashi, Go Omori, Naoto Endo

    Journal of experimental orthopaedics   6 ( 1 )   14 - 14   2019.3

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    BACKGROUND: The inclination of the medial compartment of the proximal tibia (MCT) is assumed to be a critical factor for varus alignment in advanced knee osteoarthritis (OA). This study was aimed at investigating; (1) whether the inclination of MCT is aligned parallel to the ground under weight-bearing (WB) conditions; (2) whether this is associated with the change in alignment and the relative position between the bones; and (3) whether the tibia or femur mainly contributes to the changes. METHODS: We examined 102 knees (84 women, 18 men; mean 75 years). A three-dimensional (3D) assessment system was applied on biplanar whole lower extremity radiographies using 3D-to-2D image registration technique. The evaluation parameters were 1) MCT angle, 2) femorotibial angle (FTA), 3) medial-lateral femoral location to the tibia (M-L femoral location), 4) WB line passing point, and 5) tibial position to WB line (tibial position) and 6) femoral postion to WB line (femoral position). Each parameter was evaluated in non-WB and WB conditions, and the differences (Δ-parameters). RESULTS: MCT angle in the world coordinate system was larger than that in the tibial coordinate system (p <  0.0001). ΔMCT angle was correlated with ΔFTA (p = 0.002) and ΔM-L femoral location (p = 0.004). The tibial position was the more dominant factor for ΔMCT angle (p = 0.001), ΔFTA (p <  0.0001), and ΔWB line passing point (p <  0.0001) . CONCLUSIONS: The inclination in MCT was aligned parallel to the ground under WB conditions (tibial parallel phenomenon). The parallel phenomenon was associated with the change of alignment and the relative position between the bones in the coronal plane. These phenomena were produced mainly by the tibia, not the femur. LEVEL OF EVIDENCE: Level IV.

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  • 進行期変形性膝関節症患者における脛骨近位内側関節面の水平化機序 三次元評価による臥位と立位の比較

    望月 友晴, 谷藤 理, 古賀 良生, 森 隆弘, 小林 公一, 古賀 寛, 大森 豪, 遠藤 直人

    日本整形外科学会雑誌   93 ( 3 )   S587 - S587   2019.3

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  • 早期OAの評価と治療介入のタイミング 早期OAへの筋力の影響

    大森 豪, 西野 勝敏, 高木 繁, 古賀 寛, 古賀 良生

    日本関節病学会誌   37 ( 3 )   195 - 195   2018.10

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  • DRR画像を用いた二次元画像上の大腿骨・脛骨間の回旋評価法の精度検証

    森 隆裕, 古賀 良生, 小林 公一, 古賀 寛, 望月 友晴, 勝見 亮太, 大森 豪, プラムディタ・ジョナス・アディティヤ, 田邊 裕治

    臨床バイオメカニクス   39   125 - 129   2018.10

  • Quadriceps muscle weakness is related to increased risk of radiographic knee OA but not its progression in both women and men: the Matsudai Knee Osteoarthritis Survey. International journal

    Shigeru Takagi, Go Omori, Hiroshi Koga, Kazuo Endo, Yoshio Koga, Atsushi Nawata, Naoto Endo

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA   26 ( 9 )   2607 - 2614   2018.9

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    PURPOSE: The purpose of this study was to investigate the causal relationship between quadriceps muscle strength and radiographic knee osteoarthritis (OA) in a longitudinal study. METHODS: The present study included 976 knees from 488 subjects who participated in both the 5th (2007) and 7th (2013) surveys of the Matsudai Knee Osteoarthritis Survey. Bilateral quadriceps strengths of each subject were measured using the quadriceps training machine (QTM-05F, Alcare Co., Ltd., Tokyo, Japan). Additionally, weight-bearing standing knee radiographs were obtained, and knee OA was graded according to the Kellgren-Lawrence classification system. The relationships between quadriceps strength and the incidence and progression of radiographic knee OA were assessed using multiple logistic regression analysis. RESULTS: After adjusting for age and body mass index (BMI), both female and male knees in the lowest quantile of quadriceps strength had higher risk of the incidence of radiographic knee OA compared with the highest quantile of quadriceps strength (women: OR 2.414, 95% CI 1.098-5.311; men: OR 2.774, 95% CI 1.053-7.309). In contrast, after adjusting for age, BMI and femorotibial angle, both female and male knees in the lowest quantile compared with the highest quantile of quadriceps strength did not differ in risk of the progression of radiographic knee OA (women: OR 1.040, 95% CI 0.386-2.802; men: OR 2.814, 95% CI 0.532-14.898). CONCLUSION: Quadriceps muscle weakness was related to increased risk of the incidence of radiographic knee OA, but not its progression, in both women and men. Therefore, the clinically important finding of this study is that, in both women and men, maintaining higher quadriceps muscle strength may be one of the most effective prevention methods for incident radiographic knee OA. LEVEL OF EVIDENCE: II.

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  • 変形性膝関節症の発症と大腿骨遠位骨皮質幅の関係 松代膝検診の縦断研究の結果から

    富山 泰行, 大森 豪, 古賀 良生, 望月 友晴, 谷藤 理, 古賀 寛, 西野 勝敏, 遠藤 直人

    日本整形外科学会雑誌   92 ( 8 )   S2015 - S2015   2018.8

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  • 早期変形性膝関節症の立位単純X線正面像における複数個所の骨棘評価 大規模集団検診による疫学調査から

    古賀 寛, Felson David T., 大森 豪, 古賀 良生, 谷藤 理, 望月 友晴, 遠藤 直人

    日本整形外科学会雑誌   92 ( 3 )   S1017 - S1017   2018.3

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  • 早期膝OAの病態 下肢アライメントと骨形態変化からみた早期OAの病態

    望月 友晴, 谷藤 理, 古賀 良生, 古賀 寛, 佐藤 卓, 渡邉 聡, 大森 豪, 遠藤 直人

    日本整形外科学会雑誌   92 ( 2 )   S436 - S436   2018.3

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  • Increasing incidence of fracture and its sex difference in school children: 20 year longitudinal study based on school health statistic in Japan.

    Hiroshi Koga, Go Omori, Yoshio Koga, Osamu Tanifuji, Tomoharu Mochizuki, Naoto Endo

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   23 ( 1 )   151 - 155   2018.1

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    BACKGROUND: Studies on the epidemiology of pediatric fractures have been scarce in recent years although fractures are very common in childhood. Boys have a higher incidence of fractures than girls. Currently, societal trends have seemed to influence the difference in activity patterns between boys and girls, but the sex difference regarding longitudinal changes in fracture incidence is not well known. METHODS: We analyzed the school accident report in Niigata city, Japan and compared the incidence of fractures in elementary and junior high school students and the sex-related risk ratio between two 9-year periods separated by 20 years from their start and end points (1999-2007 and 1979-1987). RESULTS: The study included 383,273 students from 1999 to 2007 and 561,109 students from 1979 to 1987. Comparing these periods, the fracture incidence increased significantly by 2.4 times in boys vs 2.1 times in girls from elementary school and by 2.2 times in boys vs 2.9 times in girls from junior high school (all p < 0.001). The sex-related risk ratio of boys to girls increased significantly from 1.47 to 1.64 in elementary school students. In contrast, it decreased significantly from 3.29 to 2.52 in junior high school students and the change was markedly significant because of the drastic increase in fracture incidence in junior high school girls. CONCLUSIONS: The reasons proposed for the increase in schoolchildren's fractures were an improvement in diagnosis owing to social background and increased participation in sports activities despite the general decline in children's physical fitness and exercise ability. In junior high school girls, in particular, there was an increase in fracture risk due to increased participation in sports activities.

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  • No differences in objective dynamic instability during acceleration of the knee with or without subjective instability post-total knee arthroplasty. International journal

    Tatsuya Soeno, Tomoharu Mochizuki, Osamu Tanifuji, Hiroshi Koga, Takayuki Murayama, Hiroki Hijikata, Yuki Takahashi, Naoto Endo

    PloS one   13 ( 3 )   e0194221   2018

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    INTRODUCTION: Instability after total knee arthroplasty is a critical problem. The purpose of this study was to clarify the stability of implanted knees during walking by comparing differences in dynamic instability during knee acceleration between individuals with or without previously experienced subjective instability, as measured by self-reported questionnaire. MATERIALS AND METHODS: We examined 92 knees with medial pivot implants. Mean patient age and follow-up duration were 78.4 years and 32.8 months, respectively. An accelerometer was used to investigate the accelerations along three axes; that is, vertical (VT), mediolateral (ML), and anteroposterior (AP) directions in 3-dimensional (3D) space. The analysis in the stance phase and gait cycle was performed by: (1) root mean square (RMS) values of acceleration and (2) frequency domain analysis using fast Fourier transformation (FFT). A self-reported knee instability score was used for the subjective feeling of instability. RESULTS: A total of 76 knees did not feel unstable (group 0), but 16 knees felt unstable (group 1) in patients during activities of daily living. Regarding the RMS, there were no differences in each direction between the groups. For FFT, the cumulative amplitude in the frequency < 30 Hz also showed no significant differences in all directions between the groups during the stance phase (VT, p = 0.335; ML, p = 0.219; AP, p = 0.523) or gait cycle (VT, p = 0.077; ML, p = 0.082; AP, p = 0.499). DISCUSSION: Gait analysis based on the acceleration data showed that there were no between-group differences in objective dynamic instability during acceleration of the knee, with or without reports of previously experienced subjective instability, as assessed by the self-reported questionnaire.

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  • Correlation between posterior tibial slope and sagittal alignment under weight-bearing conditions in osteoarthritic knees. International journal

    Tomoharu Mochizuki, Osamu Tanifuji, Yoshio Koga, Takashi Sato, Koichi Kobayashi, Satoshi Watanabe, Toshihide Fujii, Hiroshi Yamagiwa, Ryota Katsumi, Hiroshi Koga, Go Omori, Naoto Endo

    PloS one   13 ( 9 )   e0202488   2018

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    INTRODUCTION: Posterior tibial slope (PTS) and sagittal alignment are important factors in the etiology of knee osteoarthritis and knee surgery. Clinically, sagittal alignment, which indicates flexion contracture of the knee, contributes to knee function in weight-bearing (WB) conditions. PTS and sagittal alignment under WB conditions in varus osteoarthritic knees are presumed to affect each other, but their association remains unclear. In this study, we aimed to clarify the association. MATERIAL AND METHODS: In total, 140 osteoarthritic varus knees were investigated. Under WB conditions, a three-dimensional (3D) alignment assessment system was applied via biplanar long-leg X-rays, using 3D-to-2D image registration technique. The evaluation parameters were as follows: 1) 3D mechanical flexion angle (3DMFA) in regards to sagittal alignment, 2) passing point in the WB line (PP), and 3) medial and lateral PTS. RESULTS: The medial and lateral PTS showed a positive correlation with 3DMFA and PP, respectively (medial PTS-3DMFA, p = 0.001; medial PTS-PP, p < 0.0001; lateral PTS-3DMFA, p < 0.0001; lateral PTS-PP, p = 0.002). The flexion contracture group with 3DMFA >5° demonstrated greater PTS than non-flexion contracture group (medial PTS, p = 0.006; lateral PTS, p = 0.006). CONCLUSIONS: Both medial and lateral PTS were correlated with sagittal alignment under WB conditions and were larger in the flexion contracture group. This finding can explain the function to take the load articular surface parallel to the ground for holding the balance in WB conditions in the sagittal plane for osteoarthritic knees. Moreover, surgeons may be required to decrease the PTS during knee arthroplasty to restore full extension in knees of patients with fixed flexion contracture.

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  • The biomechanical effect of tunnel placement on ACL graft forces in double-bundle ACL reconstruction - A 3D computational simulation. International journal

    Nathan H Varady, Willem A Kernkamp, Jingsheng Li, Lianxin Wang, Hiroshi Koga, Peter Asnis, Guoan Li

    The international journal of medical robotics + computer assisted surgery : MRCAS   13 ( 4 )   2017.12

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    BACKGROUND: The posterolateral (PL) graft experiences a high failure rate in anterior cruciate ligament double-bundle (DB) reconstruction. It is hypothesized that tunnel positions could dramatically affect the graft forces. METHODS: A validated computational model was used to simulate DB reconstruction with various femoral PL tunnel locations (8-11 mm center-center tunnel spacing). Graft fixation was simulated at both 0° and 30°. Knee biomechanics were examined with the knee under a 134 N anterior load and 400 N quadriceps load at 0°, 30°, 60°, and 90° of flexion. Graft forces, tibial translation, and tibial rotation were calculated. RESULTS: PL graft forces at full extension increased with increasing tunnel spacing under both fixation settings, but the knee kinematics was not dramatically affected. CONCLUSION: Small changes in the femoral PL tunnel position could result in large changes in graft forces, implying that precise PL tunnel position is an important factor in a successful DB reconstruction.

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  • Association between anteroposterior laxity in mid-range flexion and subjective healing of instability after total knee arthroplasty. International journal

    Tomoharu Mochizuki, Osamu Tanifuji, Takashi Sato, Hiroki Hijikata, Hiroshi Koga, Satoshi Watanabe, Yukimasa Higano, Akihiro Ariumi, Takayuki Murayama, Hiroshi Yamagiwa, Naoto Endo

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA   25 ( 11 )   3543 - 3548   2017.11

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    PURPOSE: Flexion instability following total knee arthroplasty (TKA) is a common indication of early revision. The association between the objective anteroposterior (AP) laxity direction in mid-range flexion and the subjective healing of instability remains unclear; thus, this study aimed to clarify this association. METHODS: In this study, 110 knees (74 females, 92 knees; 16 males, 18 knees) with medial pivot implants were examined with a median age of 79 (range 60-92) years for a median follow-up duration of 22 (range 6-125) months. AP laxity was measured using a KT-1000 arthrometer. Self-reported knee instability score was used for the subjective healing of instability. RESULTS: Eighty-seven knees did not feel unstable (Group 0), whereas 23 knees felt unstable (Group 1). There was a significant difference in AP displacement [Group 0: median 6 mm; range 2-15 mm and Group 1: median 8 mm; range 4-14; p < 0.0001]. The threshold value of 7 mm was determined using the area under receiver operating characteristic curve of 0.79 [95% confidence interval (CI) 0.69-0.88, p < 0.0001]. In multivariate analysis, AP displacement of ≥7 mm was an independent risk factor for feelings of instability (odds ratio 7.695; 95% CI 2.306-25.674; p = 0.001). CONCLUSIONS: AP laxity of ≥7 mm represents a known cause of feelings of instability. By controlling AP laxity in TKAs, without stiffness in the knee, it is possible to prevent feelings of instability. The clinical relevance is that AP laxity of <7 mm is one of the target areas in TKA. LEVEL OF EVIDENCE: IV.

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  • 膝前後X線像における大腿骨・脛骨回旋評価法の検討

    森 隆裕, 田邊 裕治, 古賀 寛, 望月 友晴, 小林 公一, 古賀 良生

    臨床バイオメカニクス   38   313 - 318   2017.10

  • 加速度計を用いたTKA後の安定性評価

    添野 竜也, 望月 友晴, 谷藤 理, 佐藤 卓, 渡辺 聡, 有海 明央, 村山 敬之, 古賀 寛, 遠藤 直人

    JOSKAS   41 ( 4 )   208 - 208   2016.7

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  • 人工膝関節置換術後の前後不安定性と臨床成績の関係について

    大渓 一孝, 望月 友晴, 谷藤 理, 古賀 寛, 佐藤 卓, 渡邉 聡, 村山 敬之, 有海 明央, 遠藤 直人

    JOSKAS   41 ( 4 )   206 - 206   2016.7

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  • Medial pivot design人工膝関節置換術の自覚的不安定感と期待度

    望月 友晴, 谷藤 理, 古賀 寛, 佐藤 卓, 渡辺 聡, 有海 明央, 村山 敬之, 大渓 一孝, 遠藤 直人

    JOSKAS   41 ( 4 )   395 - 395   2016.7

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  • 人工膝関節置換術後設置位置評価 脛骨コンポーネントの三次元評価と二次元評価の比較検討

    谷藤 理, 望月 友晴, 佐藤 卓, 渡辺 聡, 古賀 寛, 遠藤 直人

    JOSKAS   41 ( 4 )   545 - 545   2016.7

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  • 大腿骨解剖軸(SEA、CEA、GCA)の脛骨関節面から見た垂直移動量の検討

    谷藤 理, 望月 友晴, 佐藤 卓, 渡邉 聡, 古賀 寛, 大森 豪, 古賀 良生, 遠藤 直人

    日本整形外科学会雑誌   90 ( 2 )   S296 - S296   2016.3

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  • 変形性膝関節症に対する装具療法は本当に有効か 運動解析から見た変形性膝関節症の異常動態

    大森 豪, 古賀 寛, 高木 繁, 勝見 亮太, 古賀 良生

    日本整形外科学会雑誌   89 ( 3 )   S894 - S894   2015.3

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  • 住民検診におけるモーションキャプチャーシステムを用いた内側型変形性膝関節症の歩行解析

    古賀 寛, 大森 豪, 西野 勝敏, 鳴海 賢太郎, 高木 繁, 勝見 亮太, 山際 浩史, 古賀 良生, 遠藤 和男, 遠藤 直人

    日本整形外科学会雑誌   88 ( 8 )   S1618 - S1618   2014.8

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  • ロコモティブシンドロームと大腿四頭筋力、変形性膝関節症の関連性

    高木 繁, 大森 豪, 古賀 寛, 遠藤 和男, 勝見 亮太, 有海 明央, 古賀 良生, 遠藤 直人

    日本整形外科学会雑誌   88 ( 8 )   S1540 - S1540   2014.8

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  • 変形性膝関節症のX線学的発症・進行予測における尿中CTX-IIの可能性 6年間の縦断的大規模住民検診(松代膝検診)より

    勝見 亮太, 山際 浩史, 速水 正, 田西 信睦, 古賀 寛, 高木 繁, 大森 豪, 古賀 良生

    日本整形外科学会雑誌   88 ( 8 )   S1619 - S1619   2014.8

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  • 変形性膝関節症のX線学的進行度と骨粗鬆症との関係 松代膝検診、6年の縦断的調査より

    勝見 亮太, 大森 豪, 山際 浩史, 古賀 寛, 高木 繁, 古賀 良生

    JOSKAS   39 ( 4 )   160 - 160   2014.7

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  • ロコモティブシンドロームと大腿四頭筋力の関連性

    高木 繁, 大森 豪, 古賀 良生, 古賀 寛, 勝見 亮太, 遠藤 和男, 遠藤 直人, 有海 明央

    JOSKAS   39 ( 4 )   428 - 428   2014.7

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  • ロコモティブシンドロームと大腿四頭筋力の関連性

    高木 繁, 大森 豪, 古賀 良生, 古賀 寛, 遠藤 和男, 有海 明央, 遠藤 直人

    運動器リハビリテーション   25 ( 2 )   192 - 192   2014.6

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  • 2013年度松代膝検診の概要及び変形性膝関節症の有病率

    古賀 寛, 大森 豪, 高木 繁, 勝見 亮太, 山際 浩史, 古賀 良生, 遠藤 和男, 遠藤 直人

    運動器リハビリテーション   25 ( 2 )   198 - 198   2014.6

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  • Incidence of osteoporotic fractures in Sado, Japan in 2010.

    Mayumi Sakuma, Naoto Endo, Takeo Oinuma, Dai Miyasaka, Yujiro Oguma, Kanta Imao, Hiroshi Koga, Naohito Tanabe

    Journal of bone and mineral metabolism   32 ( 2 )   200 - 5   2014.3

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    We conducted a survey of fracture incidences associated with senile osteoporosis in 2010 in Sado City, Niigata Prefecture, Japan, including compression vertebral fractures, hip fractures, distal radius fractures, and fractures of the proximal end of the humerus. We previously conducted a similar survey from 2004-2006 in Sado City. The purpose of the current study was to determine the incidence of osteoporotic fractures in Sado City in 2010 and to examine changes over time. We calculated the incidence of each fracture per 100,000 person-years based on the population of Sado City. Hip and vertebral fractures showed marked increases from 2004-2006, but a similar increase was not found from 2006-2010. The average age at injury increased in 2010 compared to 2004, except for fractures of the radius. Among the subjects with hip fractures, 14 % had a history of contralateral hip fracture. The percentage of patients taking medication for osteoporosis before injury was higher in 2010 compared with 2004, but these percentages were still only 7 and 13 % for those with subsequent hip and vertebral fractures, respectively.

    DOI: 10.1007/s00774-013-0486-1

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  • 軟骨下骨嚢腫を有する距骨骨軟骨損傷に対し関節鏡視下逆行性海綿骨柱移植術を施行した2例

    高木 繁, 山際 浩史, 渡邉 聡, 大森 豪, 古賀 寛, 村岡 治, 遠藤 直人

    東北整形災害外科学会雑誌   56 ( 1 )   117 - 120   2013.6

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  • 軟骨下骨骨嚢腫を有する距骨骨軟骨損傷に対する関節鏡視下逆行性海綿骨柱移植術の2例

    高木 繁, 山際 浩史, 渡邉 聡, 古賀 寛, 遠藤 直人, 大森 豪

    東北整形災害外科学会雑誌   56 ( 1 )   209 - 210   2013.6

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  • 第5中足骨粗面部骨端症と同部遺残障害例の検討

    大森 豪, 山際 浩史, 渡邊 聡, 高木 繁, 古賀 寛

    東北整形災害外科学会雑誌   56 ( 1 )   206 - 207   2013.6

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  • 新潟県におけるACL再建術の現状

    山際 浩史, 渡邉 聡, 古賀 寛, 高木 繁, 大森 豪

    新潟整形外科研究会会誌   29 ( 1 )   31 - 35   2013.3

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  • 新潟県におけるACL再建術の現状

    山際 浩史, 渡邉 聡, 古賀 寛, 高木 繁, 大森 豪

    新潟整形外科研究会会誌   28 ( 2 )   142 - 142   2012.6

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MISC

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Presentations

  • Treatments for the management of early knee osteoarthritis.Skeletal deformity in early knee osteoarthritis

    2022.6 

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    Event date: 2022.6

    Presentation type:Symposium, workshop panel (nominated)  

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  • Skeletal deformity in early knee osteoarthritis

    Hiroshi Koga, Go Omori, Tomoharu Mochizuki, Osamu Tanifuji, Yasuyuki Tomiyama, Yoshio Koga, Naoto Endo

    11th JOSKAS  2019.6 

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    Event date: 2019.6

    Language:English   Presentation type:Symposium, workshop panel (nominated)  

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  • 新潟県小千谷市における乳児股関節エコー検診

    2023年度 第11回運動器の健康・日本協会 日本賞 表彰式  2023.4 

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  • 骨粗鬆症クライシス 今、地域医療に求められるOLS(骨粗鬆症リエゾンサービス)

    小千谷学術講演会  2023.2 

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  • サルコペニア、ロコモ、フレイルからみた松代膝検診

    第13回新潟オンラインボーンクラブ  2022.11 

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  • 骨粗鬆症クライシス!骨折予防とフレイル・ロコモ

    小千谷市骨粗鬆症検診結果説明会  2022.11 

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  • フレイル予防骨粗鬆症予防

    小千谷市高梨保健推進委員活動  2022.7 

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  • 目指せ健康長寿!フレイル予防で生涯元気

    小千谷市片貝保健推進委員活動  2022.7 

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  • フレイル、ロコモと骨粗鬆症治療 Invited

    旭化成ファーマ新潟営業所社内講演会  2021.4 

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  • 元気に年トレ フレイル予防!

    デイホームいわさわ20周年記念講演  2020.11 

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  • 地域に広げるフレイル予防

    小千谷市通いの場研修会  2020.10 

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  • フレイルを知って介護予防!

    新潟県厚生連小千谷総合病院 病院祭 記念講演  2020.10 

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  • スポーツ推進委員研修講演

    小千谷市スポーツ推進委員協議会  2020.1 

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  • やわらかいから強い!? 健康な体だから、うごくのがたのしい!!

    小千谷市立南小中学校PTA合同講演会  2019.10 

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  • 骨粗鬆症を知ってロコモ、フレイル予防

    小千谷市骨粗鬆症検診結果説明会  2019.9 

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  • 足腰丈夫に、フレイル予防!

    小千谷市岩沢地区住民講演会  2019.6 

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  • 足腰丈夫に、フレイル予防!

    小千谷市保健推進協議会定期総会 記念講演  2019.5 

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  • フレイルを知ってデイホームで介護予防!!

    小千谷市デイホーム事業者研修会 記念講演  2019.2 

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Awards

  • 奨励賞

    2024.1   公益財団法人 運動器の健康・日本協会   松代膝検診

    松代膝検診研究班

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  • Award for excellence

    2023.1   Bone and Joint Japan  

    Division of Musculoskeletal Science for Frailty Niigata University Graduate School of Medical and Dental Sciences

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  • Japan Foundation Award

    2020   Japan Orthopaedics and Traumatology Foundation, Inc.  

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  • Academic Research Grant of Niigata Medical Association.

    2018   Niigata Medical Association.  

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Research Projects

  • 発育性股関節形成不全のエコー診断を補助する三次元画像解析技術の開発

    Grant number:23K08671

    2023.4 - 2026.3

    System name:科学研究費助成事業 基盤研究(C)

    Research category:基盤研究(C)

    Awarding organization:日本学術振興会

    古賀 寛

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    Authorship:Principal investigator 

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

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  • 成人期脊柱変形の進行メカニズム~骨格筋減少に着目した大規模コホート研究

    Grant number:20K09430

    2020.4 - 2023.3

    System name:科学研究費助成事業 基盤研究(C)

    Research category:基盤研究(C)

    Awarding organization:日本学術振興会

    渡邊 慶, 古賀 寛, 中村 和利, 大橋 正幸

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    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

    令和3年度に、地域型コホートとして、新潟県阿賀野市での住民272名(女性259名、男性13名、年齢72.8歳)を対象に、脊椎アライメント・運動機能・腰痛および歩行能力の低下する運動器障害であるロコモティブシンドローム(ロコモ)、サルコペニア、フレイルに関する評価を行った。令和2年度の調査では、腰痛および腰痛関連QOLがロコモの進行度との関連を解析したが、令和3年度の調査ではフレイルと調査項目との関連について解析を行った。フレイル群では、Oswestry Disability Index、腰痛VAS、SF-8の身体的サマリースコア、ロコモ25質問票が不良であった(全てp<0.05)。身体機能では最大一歩幅においてフレイル群で不良であった(p<0.05)。本調査からフレイルと慢性腰痛、ロコモとの関連を認め、腰痛およびロコモ対策の重要性が示唆された。
    また令和3年度には、都市型コホートとして埼玉県行田市整形外科クリニックで
    219名(全例女性、平均年齢72.7歳)から阿賀野市コホートと同様の調査を実施した。本調査ではISOFORCE GT-350(OG Wellness Technologies Co., Ltd., Okayama, Japan)を用いて体幹筋の等尺性筋力と骨密度(腰椎・大腿骨)も独自に評価を行っている。結果体幹筋力と静的・動的バランス機能・歩行機能と有意な関連を認め(全てp<0.05)、体幹筋力維持の重要性が示唆された。今年度は症例数を300名以上とするため調査を継続する予定。
    合計600名以上の地域型および都市型コホートの横断調査データから、脊椎アライメントに関連する、全身状態、骨格筋力、歩行・バランス機能について解析を行い、成人期脊柱変形の進行に関与する因子を解析する予定。

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  • 変形性膝関節症の自然経過と有症に至る運動学的因子の解明

    Grant number:19K18527

    2019.4 - 2022.3

    System name:科学研究費助成事業 若手研究

    Research category:若手研究

    Awarding organization:日本学術振興会

    古賀 寛

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    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

    予定していた現地疫学調査を2019年7月に実施した。予定通り約500名の被験者を獲得することができた。被験者の高齢化に伴い何割かはすべての検査項目を完遂できず、欠損値を含むデータ群となっているが、主目的の一つである縦断データに関しては概ね当初期待していた程度の被験者数を確保することができた。現在は調査にて取得したデータの解析作業を行っている段階である。本年度末頃より学会等での発表を開始できる見込みである。

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  • Epidemiological and new kinematic analysis for pathology of knee osteoarthritis

    Grant number:19K09610

    2019.4 - 2022.3

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

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    Grant amount:\4030000 ( Direct Cost: \3100000 、 Indirect Cost:\930000 )

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Teaching Experience (researchmap)

  • Sports Medicine

    2019.4
    Institution name:Apple Sports college, Niigata, Japan

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  • Orthopaedic Surgery

    2010.10
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    2011.9
    Institution name:Sado College of Nursing, Sado, Japan

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  • Orthopaedic Surgery

    2010.4
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    2010.9
    Institution name:Chuo College of Nursing, Nagaoka, Japan

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Social Activities

  • シリーズプロフェッサー vol.44 「サルコペニアの重要性と予防法」

    Role(s): Contribution

    株式会社テレビ新潟放送網  HIROBA  2020

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  • おぢや健康だより

    Role(s): Editer, Planner, Contribution

    新潟県小千谷市  広報おぢや  2019.4

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  • シリーズプロフェッサー vol.40 「増えている?小中学生の骨折」

    Role(s): Contribution

    株式会社テレビ新潟放送網  HIROBA  2019

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  • シリーズプロフェッサー vol.24 「変形性膝関節症」

    Role(s): Contribution

    株式会社テレビ新潟放送網  HIROBA  2015

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Media Coverage

  • 医療、健康理解深める 小千谷でセミナー Newspaper, magazine

    新潟日報社  新潟日報  2024.6

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  • 乳児に股関節エコー Newspaper, magazine

    新潟日報社  新潟日報  2024.4

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  • 乳児健診でエコー活用 Newspaper, magazine

    読売新聞社  読売新聞新潟版  2024.4

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  • 最新医療情報「発育性股関節形成不全」 Promotional material

    新潟県厚生農業協同組合連合会  支えに  2024.4

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  • 中学女子 骨折発生率6.5倍 Newspaper, magazine

    読売新聞社  読売新聞新潟版  2019.3

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