Updated on 2025/12/09

写真a

 
MATSUI Ko
 
Organization
University Medical and Dental Hospital Intensive Care Unit Assistant Professor
Title
Assistant Professor
External link

Degree

  • 学士(医学) ( 2004.3   新潟大学 )

Research History

  • Niigata University   University Medical and Dental Hospital Intensive Care Unit   Assistant Professor

    2019.4

 

Papers

  • 小児における高難度医療を迅速に行うためには

    馬場 恵史, 水流 宏文, 塚田 正範, 阿部 忠朗, 沼野 藤人, 谷 瑞生, 布施 理子, 泉田 侑恵, 額賀 俊介, 松井 亨, 高橋 利典, 杉本 愛, 渡邉 マヤ, 白石 修一, 齋藤 昭彦

    日本小児科学会雑誌   128 ( 10 )   1349 - 1349   2024.10

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  • Acute Flaccid Myelitis With Human Rhinovirus A19 Detection: Case Report and Literature Review Reviewed

    Yurie Murayama, Yuta Aizawa, Tatsuki Ikuse, Ryohei Izumita, Shunsuke Nukaga, Masahiro Kaneko, Takeshi Yamada, Takeshi Ono, Ko Matsui, Masashi Suda, Akihiko Saitoh

    Pediatric Infectious Disease Journal   2024.3

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    DOI: 10.1097/INF.0000000000004317

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  • ECMO脱血カニューレが上行腰静脈経由で下大静脈に留置されたが静脈造影下の抜去に成功した1例

    本田 博之, 栗田 秀一郎, 松井 亨, 大橋 さとみ, 平田 哲大, 堀井 陽祐, 西山 慶

    日本救急医学会雑誌   35 ( 1 )   22 - 27   2024.1

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  • ECMO脱血カニューレが上行腰静脈経由で下大静脈に留置されたが静脈造影下の抜去に成功した1例

    本田 博之, 栗田 秀一郎, 松井 亨, 大橋 さとみ, 平田 哲大, 堀井 陽祐, 西山 慶

    日本救急医学会雑誌   35 ( 1 )   22 - 27   2024.1

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  • 敗血症性心筋障害とはなんだろうか? 敗血症性心筋障害 診断と治療の実際

    西山 慶, 松井 亨, 晝間 優貴, 布施 理子, 大橋 さとみ, 本多 忠幸

    日本集中治療医学会雑誌   30 ( Suppl.1 )   S319 - S319   2023.6

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  • 集中治療室の小児患者における,バンコマイシンのトラフ値と推定AUCの相関に関する,後方視的検討

    松井 亨, 宮入 悠二, 晝間 優隆, 布施 理子, 本田 博之, 大橋 さとみ, 本多 忠幸, 西山 慶

    日本集中治療医学会雑誌   30 ( Suppl.1 )   S428 - S428   2023.6

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  • デクスメデトミジンを用いてリハビリテーションを行った重症全身性破傷風の1例

    晝間 優隆, 番場 祐基, 土田 雅史, 松井 亨, 本田 博之, 西山 慶

    日本臨床麻酔学会誌   43 ( 3 )   193 - 197   2023.5

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  • COVID-19肺炎により重症呼吸不全を呈したBMI70を超える病的肥満患者にV-V ECMOを導入し救命した1例

    青木 志門, 本田 博之, 玉川 大朗, 番場 祐基, 土田 雅史, 晝間 優隆, 松井 亨, 西山 慶

    人工呼吸   40 ( 1 )   79 - 84   2023.5

  • COVID-19肺炎により重症呼吸不全を呈したBMI70を超える病的肥満患者にV-V ECMOを導入し救命した1例

    青木 志門, 本田 博之, 玉川 大朗, 番場 祐基, 土田 雅史, 晝間 優隆, 松井 亨, 西山 慶

    人工呼吸   40 ( 1 )   79 - 84   2023.5

  • デクスメデトミジンを用いてリハビリテーションを行った重症全身性破傷風の1例

    晝間 優隆, 番場 祐基, 土田 雅史, 松井 亨, 本田 博之, 西山 慶

    日本臨床麻酔学会誌   43 ( 3 )   193 - 197   2023.5

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  • 本邦で初めて中毒性表皮壊死症にエタネルセプトを投与した1例

    荻根沢 真帆子, 濱 菜摘, 武居 いづみ, 土田 裕子, 酒井 あかり, 長谷川 瑛人, 阿部 理一郎, 金子 昌弘, 金子 詩子, 松井 亨, 本田 博之

    日本皮膚免疫アレルギー学会総会学術大会プログラム・抄録集   52回   193 - 193   2022.12

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  • エタネルセプトが著効した小児中毒性表皮壊死症(TEN)の1例

    武居 いづみ, 長谷川 瑛人, 荻根沢 真帆子, 土田 裕子, 酒井 あかり, 濱 菜摘, 阿部 理一郎, 金子 昌弘, 金子 詩子, 晝間 優隆, 松井 亨, 本田 博之

    西日本皮膚科   84 ( 6 )   575 - 575   2022.12

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  • 外傷後難治性症候性てんかんによるけいれん重積後に多臓器不全を呈し急性肝不全で不良な転機を辿った一例

    土田 雅史, 本田 博之, 晝間 優隆, 青木 志門, 玉川 大朗, 番場 祐基, 松井 亨, 新田 正和, 本多 忠幸, 西山 慶

    日本集中治療医学会雑誌   29 ( Suppl.1 )   617 - 617   2022.11

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  • 鎮静鎮痛下で極期からの覚醒下早期リハビリテーションに成功し、重篤な機能障害なく退院した全身性破傷風

    晝間 優隆, 本田 博之, 玉川 大朗, 青木 志門, 番場 祐基, 土田 雅史, 松井 亨, 新田 正和, 本多 忠幸, 西山 慶

    日本集中治療医学会雑誌   29 ( Suppl.1 )   688 - 688   2022.11

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  • 高度肥満(BMI70)のCOVID-19肺炎に対してV-V ECMOを導入した一例

    青木 志門, 本田 博之, 玉川 大朗, 番場 祐基, 土田 雅史, 晝間 優隆, 松井 亨, 新田 正和, 本多 忠幸, 西山 慶

    日本集中治療医学会雑誌   29 ( Suppl.1 )   635 - 635   2022.11

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  • 脊髄損傷による便秘が原因で全大腸壊死に至った一例

    木村 胤元, 川井 洋輔, 柴田 健継, 出内 主基, 栗田 秀一郎, 布施 理子, 晝間 優隆, 松井 亨, 本田 博之, 本多 忠幸, 西山 慶

    日本救急医学会雑誌   33 ( 10 )   879 - 879   2022.10

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  • エタネルセプト(ETN)が奏効した小児中毒性表皮壊死症(TEN)の1例 Reviewed

    武居 いづみ, 長谷川 瑛人, 鈴木 紗也佳, 荻根沢 真帆子, 木村 浄土, 安齋 理, 土田 裕子, 酒井 あかり, 濱 菜摘, 阿部 理一郎, 金子 昌弘, 金子 詩子, 晝間 優隆, 松井 亨, 本田 博之, 会沢 敦子

    日本皮膚科学会雑誌   132 ( 6 )   1496 - 1496   2022.5

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  • エタネルセプト(ETN)が奏効した小児中毒性表皮壊死症(TEN)の1例

    武居 いづみ, 長谷川 瑛人, 鈴木 紗也佳, 荻根沢 真帆子, 木村 浄土, 安齋 理, 土田 裕子, 酒井 あかり, 濱 菜摘, 阿部 理一郎, 金子 昌弘, 金子 詩子, 晝間 優隆, 松井 亨, 本田 博之, 会沢 敦子

    日本皮膚科学会雑誌   132 ( 6 )   1496 - 1496   2022.5

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  • 当施設の救急集中治療領域におけるAdvance Care Planning(ACP)普及の取り組み 新潟県多施設共同研究

    上村 夏生, 玉川 大朗, 晝間 優隆, 八幡 えり佳, 土田 雅史, 松井 亨, 本田 博之, 新田 正和, 本多 忠幸, 西山 慶

    日本救急医学会雑誌   32 ( 12 )   1516 - 1516   2021.11

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  • 『救急医療における多職種連携』早期栄養介入管理加算取得に関する栄養管理部との連携と、加算取得開始前後での診療内容・患者転帰の変化

    新田 正和, 小師 優子, 今井 十夢, 武田 安永, 上村 夏生, 八幡 えり佳, 土田 雅史, 番場 祐基, 本多 忠幸, 松井 亨, 晝間 優隆, 青木 信将, 本田 博之, 寺井 崇二, 西山 慶

    東北救急医学会総会・学術集会プログラム・抄録集   35回   39 - 39   2021.7

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  • Perivascular abnormalities in pediatric encephalopathy with fulminant brain edema. International journal

    Hideshi Kawashima, Yuki Abe, Kou Matsui, Kenichi Yamada

    Brain & development   43 ( 6 )   719 - 723   2021.6

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    BACKGROUND: Acute encephalopathy with acute brain swelling (ABS) is a recently proposed disease of unknown etiology, characterized by rapid progression to whole-brain swelling. To our knowledge, we reported the first case of a patient with acute encephalopathy with ABS wherein brain magnetic resonance imaging (MRI) abnormalities were noted prior to the diffuse brain swelling onset. CASE PRESENTATION: An 11-year-old boy was admitted to our unit owing to prolonged disturbance of consciousness following febrile status epilepticus. At the initial visit, the vital signs were within the normal range, except for the body temperature and consciousness level (Glasgow Coma Scale 6; E1V1M4). The initial laboratory results showed elevated inflammatory marker levels and mild hyponatremia. Cerebrospinal fluid analysis revealed albuminocytologic dissociation, whereas the myelin basic protein level was not elevated. Electroencephalography showed diffuse, high-amplitude slow waves. No abnormalities were detected on the initial brain computed tomography (CT) scan. However, at 11 h after the seizure onset, diffuse hyperintense lesions were observed throughout the cerebrum on T2-weighted brain MRI. The patient was diagnosed with acute encephalopathy and received methylprednisolone-pulse therapy (1 g) with high-dose gamma globulin (1 g/kg) administration. At 14 h after the seizure onset, the patient was declared brain-dead; the brain CT findings revealed whole-brain swelling and herniation. CONCLUSION: Our findings were suggestive of a perivascular pathophysiology and may be used for subtyping acute encephalopathy. In cases where such findings are observed, subsequent development of severe diffuse brain swelling should be considered.

    DOI: 10.1016/j.braindev.2021.01.006

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  • Polymicrogyria with calcification in Pallister-Killian syndrome detected by microarray analysis. International journal

    Akiko Hiraiwa, Kou Matsui, Yumi Nakayama, Takao Komatsubara, Shinichi Magara, Yu Kobayashi, Moemi Hojo, Mitsuhiro Kato, Toshiyuki Yamamoto, Jun Tohyama

    Brain & development   43 ( 3 )   448 - 453   2021.3

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    BACKGROUND: Pallister-Killian syndrome (PKS) is a rare disorder caused by the mosaic tetrasomy of chromosome 12p, and is characterized by facial dysmorphism, developmental delay, hypotonia and seizures. RESULTS: We report a patient with PKS showing unique polymicrogyria with calcification. He had delayed development and dysmorphic facial features including frontal bossing, hypertelorism, and high arched palate at 6 months of age. Neuroimaging revealed unilateral polymicrogyria with spot calcifications, which predominantly affected the right perisylvian region. Chromosome G-banding showed the karyotype 46,XY, however, array-based comparative genomic hybridization analysis showed mosaic duplication of chromosome 12p, in which CCND2, which encodes cyclin D2 and is a downstream mediator of PI3K-AKT pathway, is located. Supernumerary chromosome of 12p was detected in 58% of buccal mucosa cells by the interphase fluorescence in situ hybridization analysis using chromosome 12 centromere-specific D12Z3 probe. The diagnosis of PKS was made based on distinctive clinical features of our patient and the results of cytogenetic analyses. CONCLUSION: This report is, to our knowledge, the first case of a patient with PKS who clearly demonstrates polymicrogyria colocalized with calcifications, as shown by CT scans and MRI, and suggests that a patient with PKS could show structural brain anomalies with calcification. We assume that somatic mosaicism of tetrasomy could cause asymmetrical polymicrogyria in our patient, and speculate that increased dosages of CCND2 at chromosome 12p might be involved in the abnormal neuronal migration in PKS.

    DOI: 10.1016/j.braindev.2020.11.003

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  • Parechovirus-A3 encephalitis presenting with focal seizure mimicking herpes simplex virus infection. International journal

    Sakiko Arai, Takayuki Yamanaka, Masashi Kasai, Tetsuhiro Fukuyama, Yuta Aizawa, Ko Matsui, Masanori Sato, Hiroko Matsui, Akihiko Saitoh

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   26 ( 7 )   736 - 740   2020.7

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    BACKGROUND: Febrile neonates and young infants presenting with seizure require immediate evaluation and treatment. Herein we experienced two young infants with parechovirus-A3 (PeV-A3) encephalitis, initially presented with focal seizure suspecting herpes simplex virus (HSV) encephalitis. CASES: We have experienced 2 infantile cases, initially presented with focal seizure. At presentation, HSV encephalitis was strongly suspected and empiric acyclovir therapy was started; however, serum and/or cerebrospinal fluid (CSF) PCR for HSV were negative. Instead, serum and/or CSF PCR for parechovirus-A was positive. PeV-A3 infection was confirmed by genetic sequence analyses. Both cases required multiple anticonvulsant therapy and intensive care for intractable seizure. Diffusion-weighted imaging of brain magnetic resonance imaging (MRI) showed distinct findings; high-intensity lesions in the gray matter of parietal and occipital lobes in Case 1, and bilateral decreased diffusion of the deep white matter and corpus callosum in Case 2. We have followed two cases more than four years; Case 1 developed epilepsy, has been on an anticonvulsant to control her seizure. Case 2 has significant neurodevelopmental delay, unable to stand or communicate with language. CONCLUSIONS: PeV-A3 encephalitis needs to be in differential diagnosis when neonates and young infants present with focal seizure, mimicking HSV encephalitis. Special attention may be necessary in patients with PeV-A3 encephalitis given it could present with intractable seizure with high morbidity in a long-term.

    DOI: 10.1016/j.jiac.2020.02.003

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  • An autopsy case of peliosis hepatis with X-linked myotubular myopathy. International journal

    Kazuhisa Funayama, Hiroshi Shimizu, Hidetomo Tanaka, Izumi Kawachi, Ichizo Nishino, Kou Matsui, Naoya Takahashi, Akihide Koyama, Rieka Katsuragi-Go, Ryoko Higuchi, Takashi Aoyama, Hiraku Watanabe, Akiyoshi Kakita, Hisakazu Takatsuka

    Legal medicine (Tokyo, Japan)   38   77 - 82   2019.5

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    This report describes the autopsy case of a 4-year-old boy who died from hepatic hemorrhage and rupture caused by peliosis hepatis with X-linked myotubular myopathy. Peliosis hepatis is characterized by multiple blood-filled cavities of various sizes in the liver, which occurs in chronic wasting disease or with the use of specific drugs. X-linked myotubular myopathy is one of the most serious types of congenital myopathies, in which an affected male infant typically presents with severe hypotonia and respiratory distress immediately after birth. Although each disorder is rare, 12 cases of pediatric peliosis hepatis associated with X-linked myotubular myopathy have been reported, including our case. Peliosis hepatis should be considered as a cause of hepatic hemorrhage despite its low incidence, and it requires adequate gross and histological investigation for correct diagnosis.

    DOI: 10.1016/j.legalmed.2019.04.005

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  • Clinical implications of interleukin-18 levels in pediatric patients with Mycoplasma pneumoniae pneumonia. International journal

    Tomohiro Oishi, Mitsuo Narita, Kou Matsui, Takahiro Shirai, Mai Matsuo, Jun Negishi, Takayuki Kaneko, Shinya Tsukano, Tetsuo Taguchi, Makoto Uchiyama

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   17 ( 6 )   803 - 6   2011.12

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    The immunological pathogenesis of Mycoplasma pneumoniae pneumonia is known to involve several cytokines. The serum levels of interleukin-18 (IL-18) were examined using enzyme-linked immunosorbent assay in 23 pediatric patients (median age 6 years; range 4-13 years; 14 girls and 9 boys) with M. pneumoniae pneumonia admitted to our hospital. Serum levels of IL-18 ranged from 22 to 1808 pg/ml with a mean of 543 pg/ml. We started steroid therapy in two cases with IL-18 values greater than 1000 pg/ml without being aware of IL-18 levels. Examination of associations between IL-18 levels determined by enzyme-linked immunosorbent assay and a routine laboratory test showed that levels of lactate dehydrogenase (LDH) and IL-18 were significantly correlated. To determine the appropriateness of steroid administration in M. pneumoniae pneumonia patients, serum LDH should be examined. Patients with elevated levels of LDH are likely to have significantly elevated IL-18 values (≥1000 pg/ml) and thus can be candidates for steroid therapy.

    DOI: 10.1007/s10156-011-0265-7

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  • Prophylactic cefdinir for pediatric cases of complicated urinary tract infection. International journal

    Tomohiro Oishi, Kazuyuki Ueno, Kyoko Fukumoto, Kou Matsui, Shinya Tsukano, Tetsuo Taguchi, Makoto Uchiyama

    Pediatrics international : official journal of the Japan Pediatric Society   53 ( 1 )   57 - 61   2011.2

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    BACKGROUND: This study evaluated the effect of prophylactic cefdinir (3 mg/kg given once daily) for the prevention of recurrent and complicated urinary tract infections (UTI) in pediatric patients. METHODS: The study included 14 infants who were observed for at least 6 months following the first signs of infection (eight boys, six girls; mean age at admission [± SD]: 6.2 [± 7.4] months). Twelve patients had vesico-ureteric reflux (grade I, two; grade II, three; grade III, six; grade IV, one), and two patients had ureteropelvic junction stenosis. RESULTS: No patients discontinued medication due to diarrhea or other adverse drug reactions. The patients had a 6-month recurrence-free rate of 93% (13/14); only one patient had recurrent UTI. The mean urinary cefdinir concentration was 16.3 [± 11.7]µg/mL; there was considerable variability among individual measurements, even though the samples were collected at similar intervals after drug intake (mean 18.00 [± 2.63] h after dose). However, the lowest measured urinary cefdinir concentration (1.16 µg/mL) was sufficient to eradicate Escherichia coli, one of the most significant causes of UTI. Fecal cultures, obtained at monthly clinic visits during the observation period, indicated that the patients' E. coli strains were very sensitive to cefdinir. No patients were infected with Pseudomonas aeruginosa or other non-fermenting Gram-negative bacilli or fungi. CONCLUSIONS: These results show that cefdinir given 3 mg/kg once daily is very effective and safe for preventing recurrent complicated UTI in infants.

    DOI: 10.1111/j.1442-200X.2010.03190.x

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Research Projects

  • 脳波ウェーブレット変換と深層学習による蘇生後脳障害の評価法の開発

    Grant number:23K08473

    2023.4 - 2026.3

    System name:科学研究費助成事業

    Research category:基盤研究(C)

    Awarding organization:日本学術振興会

    本田 博之, 西山 慶, 松井 亨, 晝間 優隆, 八幡 えり佳, 上村 夏生

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    Grant amount:\3510000 ( Direct Cost: \2700000 、 Indirect Cost:\810000 )

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  • Creating Tailored Post-Resuscitation Care Based on Brain Injury Severity with AI Imaging

    Grant number:22K09112

    2022.4 - 2025.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

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    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

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