Updated on 2025/09/18

写真a

 
NISHIJIMA Koji
 
Organization
University Medical and Dental Hospital Perinatal Intensive Care Center Professor
Title
Professor
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Degree

  • 博士(医学) ( 2012.3   福井大学 )

Research Interests

  • micelle

  • 肺サーファクタント

  • 胎児発達

  • 胎児腸管成熟

  • fetal intestinal development

Research Areas

  • Life Science / Obstetrics and gynecology

Research History

  • Niigata University   University Medical and Dental Hospital Perinatal Intensive Care Center   Professor

    2020.12

  • Niigata University   University Medical and Dental Hospital Perinatal Intensive Care Center   Associate Professor

    2019.4 - 2020.11

Education

  • Fukui Medical University   医学部   医学科

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    Country: Japan

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Professional Memberships

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Committee Memberships

  • Japan Society of Perinatal and Neonatal Medicine   councilor  

    2010   

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    Committee type:Academic society

    Japan Society of Perinatal and Neonatal Medicine

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  • 北陸胎児心エコー研究会   世話人  

    2010   

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    Committee type:Academic society

    北陸胎児心エコー研究会

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  • 日本周産期・新生児医学会   評議員  

    2010   

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    Committee type:Academic society

    日本周産期・新生児医学会

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  • 日本周産期・新生児医学会   周産期専門医制度・施設代表指導医  

    2006   

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    Committee type:Academic society

    日本周産期・新生児医学会

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  • 北陸周産期・新生児研究会   幹事  

    2006   

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    北陸周産期・新生児研究会

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Papers

  • Letter regarding "Updated criteria for the approval of subsequent pregnancy after cesarean section with a transverse uterine fundal incision based on 17 years of experience": Our recommended measurement methodology of the scar thickness around the uterine fundus. International journal

    Hiroki Kato, Takashi Shibata, Koji Nishijima

    The journal of obstetrics and gynaecology research   51 ( 1 )   e16200   2025.1

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    DOI: 10.1111/jog.16200

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  • 胎児発育不全症例における周産期予後予測としてのsFlt-1/PlGF比測定の有用性の検討

    錦織 瑞彩, 山脇 芳, 生野 寿史, 西島 浩二

    日本周産期・新生児医学会雑誌   60 ( 3 )   397 - 402   2024.12

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    Language:Japanese   Publisher:(一社)日本周産期・新生児医学会  

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  • Influence of Warning Bleeding on Blood Loss in Low-Lying Placenta. International journal

    Hiroto Yamamoto, Kaoru Yamawaki, Kazufumi Haino, Kosuke Yoshihara, Koji Nishijima

    Cureus   16 ( 11 )   e74858   2024.11

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    Objective This study aimed to investigate whether the amount of blood loss during delivery in patients with low-lying placenta is affected by the planned mode of delivery, internal os distance, and warning bleeding. Materials and methods We conducted a single-center retrospective study encompassing women with singleton pregnancies diagnosed with low-lying placenta between January 2012 and December 2021. Data for maternal demographic details and pregnancy outcomes were extracted from the institution's records. We analyzed blood loss during delivery according to the planned delivery mode, internal os distance (≥10 mm or within 10 mm), and the occurrence of warning bleeding. We also assessed the frequency of abnormal hemorrhage at delivery. Statistical analyses included the Mann-Whitney U test and Fisher's exact probability test, with significance set at p<0.05. Results This study included 27 pregnant women. The planned delivery mode and internal os distance showed no statistically significant impact on the amount of blood loss or frequency of abnormal hemorrhage at delivery. However, the occurrence of warning bleeding had a significant effect on both factors. Conclusion In patients diagnosed with a low-lying placenta with warning bleeding, cautious delivery management is recommended owing to the possible increased risk of abnormal hemorrhage at delivery.

    DOI: 10.7759/cureus.74858

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  • Impact of gestational age on the management of acute appendicitis during pregnancy: A nationwide observational study. International journal

    Shunya Sugai, Yusuke Sasabuchi, Hideo Yasunaga, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Kosuke Yoshihara, Koji Nishijima

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics   2024.10

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    OBJECTIVE: To compare conservative management and appendectomy for acute appendicitis during pregnancy by trimester. METHODS: This retrospective cohort study used data from a national inpatient database from July 2010 to March 2022. Pregnant women diagnosed with acute appendicitis were included. Multivariable analysis using generalized estimating equations was performed to compare outcomes between conservative management and appendectomy across trimesters. The main outcomes were preterm labor, preterm delivery, or abortion; antepartum hemorrhage; duration of hospitalization; and duration of antibiotic use. RESULTS: A total of 3158 individuals from 632 acute-care hospitals were eligible. The proportion of conservative management versus appendectomy by trimester were 507 (49.1%) versus 525 (50.9%) in the first, 690 (44.6%) versus 856 (55.4%) in the second, and 337 (58.1%) versus 243 (41.9%) in the third. In the second trimester, appendectomy was associated with a higher rate of preterm delivery, preterm labor, or abortion (odds ratio [OR], 2.91 [95% confidence interval (CI), 1.62-5.25]). Antepartum hemorrhage occurred more frequently for appendectomy in the first (OR, 2.12 [95% CI, 1.31-3.43]) and third (OR, 2.43 [95% CI, 1.79-3.31]) trimesters. Appendectomy was associated with a longer duration of hospitalization in the second (2.15 days; 95% CI, 1.14-3.17 days) and third (3.97 days; 95% CI, 2.22-5.71 days) trimesters. Antibiotic use duration was shorter for appendectomy in the first (-1.20 days [95% CI -1.51 to -0.90 days]) and second (-0.61 days [95% CI -0.90 to -0.32 days]) trimesters. CONCLUSIONS: Clinical outcomes of acute appendicitis during pregnancy vary by trimester. Considering the appendectomy risks, conservative management may be viable depending on the clinical context and trimester.

    DOI: 10.1002/ijgo.15953

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  • Clinical characteristics and outcomes of preterm versus term uterine rupture: a nationwide observational study. International journal

    Shunya Sugai, Yusuke Sasabuchi, Hideo Yasunaga, Toshiaki Isogai, Kosuke Yoshihara, Koji Nishijima

    Archives of gynecology and obstetrics   2024.10

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    OBJECTIVE: To assess and compare the clinical aspects of uterine rupture by dividing the gestational age at uterine rupture occurrence into < 37-week (preterm) and ≥ 37-week (term) groups. METHODS: This retrospective cohort study analyzed data from 187 acute-care hospitals across Japan and included patients who experienced uterine rupture. Data were sourced from the Diagnosis Procedure Combination inpatient database, spanning July 2010 to March 2022. The patients' characteristics, in-hospital procedures, and outcomes were compared between those with uterine rupture at  < 37 and  ≥ 37 weeks of gestation. The main outcomes were hysterectomy, complications, proportion of blood transfusions, and postoperative length of stay. RESULTS: A total of 298 patients were identified, with 161 in the preterm group and 137 in the term group. Placenta accreta spectrum occurred more frequently in the preterm group than in the term group (18.0% vs. 6.6%, respectively; P = 0.003). Vacuum delivery (19.0% vs. 0.6%, P < 0.001) and uterine fundal pressure (2.9% vs. 0.0%, P = 0.004) were more likely to be applied in the term group. The maternal need for mechanical ventilation (26.3% vs. 12.4%, P = 0.003), the proportion of disseminated intravascular coagulation (40.1% vs. 25.5%, P = 0.009), and the requirement for platelet transfusions (32.8% vs. 15.5%, P < 0.001) were greater in the term. The postoperative hospital stays were also longer in the term group. CONCLUSION: This study shows that individual characteristics vary with the gestational age at uterine rupture, and maternal morbidity is notably higher in term compared to preterm ruptures.

    DOI: 10.1007/s00404-024-07762-1

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  • Temporal trends and regional variations in operative vaginal deliveries in Japan: A national representative cohort study. International journal

    Shunya Sugai, Yutaro Mori, Kaoru Yamawaki, Eiri Shima, Mitsuru Matsushita, Kosuke Yoshihara, Koji Nishijima

    The journal of obstetrics and gynaecology research   50 ( 9 )   1494 - 1500   2024.9

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    AIM: To analyze temporal trends and regional variations in operative vaginal delivery (OVD) in Japan. METHODS: Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan from 2014 to 2021, we identified the numbers of vacuum and forceps deliveries. We analyzed annual totals and proportions of OVDs and calculated the mean age of women undergoing these deliveries. We also predicted trends in OVD for the next 20 years and compared geographical differences in the proportions of forceps deliveries among OVDs. RESULTS: During the observation period, out of 7 368 814 total births, 8.4% were through OVD, including 7.6% by vacuum and 0.8% by forceps. Both delivery methods showed an increasing trend from 2014 to 2021: vacuum deliveries rose from 7.0% to 8.7%, and forceps deliveries increased from 0.6% to 1.0%. Notably, the proportion of forceps deliveries in OVD increased from 8.1% to 10.5%. The mean age was higher for forceps deliveries than vacuum deliveries. According to our predictions, vacuum deliveries may continue to increase, but forceps deliveries may stabilize. The proportion of forceps deliveries among OVDs ranged from 0% to 38% across Japanese prefectures. CONCLUSIONS: This study shows an increase in the use of OVD in Japan from 2014 to 2021. There are large regional differences in the choice between vacuum and forceps deliveries. These findings can help us understand the practice of OVD in Japan.

    DOI: 10.1111/jog.16039

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  • Pregnancy Following Spontaneous Healing of Uterine Rupture: A Case Report and Experience of Management. International journal

    Shunya Sugai, Kazufumi Haino, Kaoru Yamawaki, Kosuke Yoshihara, Koji Nishijima

    Cureus   16 ( 9 )   e70322   2024.9

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    Uterine rupture can heal naturally without the need for surgical intervention. However, reports on subsequent pregnancies are limited. A 27-year-old woman, gravida 2, para 1, visited our institution at seven weeks of gestation. She had previously experienced uterine rupture with postpartum hemorrhage, which had healed naturally without surgical intervention. We thoroughly explained the perinatal complications associated with the subsequent pregnancy, particularly the risk of uterine rupture recurrence, and managed her pregnancy progress carefully. We took great care to ensure that signs of a silent rupture were not missed on imaging examinations. A planned cesarean delivery was performed at 35 weeks of gestation, resulting in an uneventful pregnancy outcome. We report the details of our management of a subsequent pregnancy in a woman who had previously experienced uterine rupture with natural healing. Our findings may serve to support healthcare providers managing similar cases.

    DOI: 10.7759/cureus.70322

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  • 【周産期(産科)の手術の工夫-筆者はこうしている】前置胎盤の手術 子宮底部横切開

    柴田 貴司, 西島 浩二

    周産期医学   54 ( 8 )   1129 - 1135   2024.8

  • 妊娠糖尿病合併妊婦における産後糖代謝異常リスクの検討

    山田 貴穂, 柳生田 紀子, 西島 浩二, 小川 洋平, 谷内 洋子, 吉原 弘祐, 曽根 博仁

    糖尿病と妊娠   24 ( 2 )   S - 106   2024.8

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    Language:Japanese   Publisher:(一社)日本糖尿病・妊娠学会  

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  • 当院における周産期レジストリーを用いた妊娠糖尿病の転帰や予後の検討

    柳生田 紀子, 山田 貴穂, 西島 浩二, 有森 直子, 小川 洋平, 吉原 弘祐, 曽根 博仁

    糖尿病と妊娠   24 ( 2 )   S - 102   2024.8

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  • A case of fetal hydrops caused by generalized arterial calcification of infancy.

    Eiri Shima, Kazufumi Haino, Shunya Sugai, Kazuaki Suda, Koji Nishijima, Kosuke Yoshihara

    Journal of medical ultrasonics (2001)   51 ( 2 )   367 - 368   2024.4

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    DOI: 10.1007/s10396-023-01404-w

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  • The three-factor structure of the Autism-Spectrum Quotient Japanese version in pregnant women

    Ekachaeryanti Zain, Naoki Fukui, Yuichiro Watanabe, Koyo Hashijiri, Takaharu Motegi, Maki Ogawa, Jun Egawa, Koji Nishijima, Toshiyuki Someya

    Frontiers in Psychiatry   14   2023.10

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    Background

    There is a rising interest in perinatal mental health studies, and proper psychometric tools to assess autistic traits among this population in Japan are vital.

    Objective

    This study aimed to clarify the optimal factor structure of the AQ as part of a perinatal mental health research project.

    Methods

    We used the Japanese version of the AQ (AQ-J) to measure autistic-like traits in pregnant women. Participants were 4,287 Japanese women who were pregnant or who had given birth within the last month. We performed exploratory factor analysis (EFA) using the first sample group (n = 2,154) to obtain factor structures for the final item selections. We performed confirmatory factor analysis (CFA) using the second sample group (n = 2,133) to obtain a model with good fit, then compared the model to all previously proposed models to determine the best-fitting model.

    Results

    The EFA analysis identified a model consisting of 25 items distributed across three factors. Cronbach’s alpha for the total 25-item AQ-J, 9-item “Social interaction” factor, 11-item “Non-verbal communication” factor, and 5-item “Restricted interest” factor was 0.829, 0.829, 0.755, and 0.576, respectively. McDonald’s omega and its 95% confidence interval were 0.826 (0.821–0.836), 0.835 (0.821–0.837), 0.755 (0.744–0.766), and 0.603 (0.556–0.596), respectively. CFA confirmed that the three-factor structure had an acceptable fit (goodness of fit index: 0.900, comparative fit index: 0.860, root mean square error of approximation: 0.066). These findings indicated that the three-factor model was better than the 13 existing models.

    Conclusion

    The findings are discussed in relation to the adequacy of the AQ-J for assessing autistic traits in perinatal women. We recommend the use of this 25-item, three-factor AQ-J model for this population owing to its superiority to all previous models.

    DOI: 10.3389/fpsyt.2023.1275043

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  • Incidence of Recurrent Uterine Rupture: A Systematic Review and Meta-analysis. International journal

    Shunya Sugai, Kaoru Yamawaki, Kazufumi Haino, Kosuke Yoshihara, Koji Nishijima

    Obstetrics and gynecology   2023.10

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    OBJECTIVE: We aimed to quantify the incidence of recurrent uterine rupture in pregnant women. DATA SOURCES: A literature search of PubMed, Web of Science, Cochrane Central, and ClinicalTrials.gov for observational studies was performed from 2000 to 2023. METHODS OF STUDY SELECTION: Of the 7,440 articles screened, 13 studies were included in the final review. We included studies of previous uterine ruptures that were complete uterine ruptures , defined as destruction of all uterine layers, including the serosa. The primary outcome was the pooled incidence of recurrent uterine rupture. Between-study heterogeneity was assessed with the I2 value. Subgroup analyses were conducted in terms of the country development status, year of publication, and study size (single center vs national study). The secondary outcomes comprised the following: 1) mean gestational age at which recurrent rupture occurred, 2) mean gestational age at which delivery occurred without recurrent rupture, and 3) perinatal complications (blood loss, transfusion, maternal mortality, and neonatal mortality). TABULATION, INTEGRATION, AND RESULTS: A random-effects model was used to pool the incidence or mean value and the corresponding 95% CI with R software. The pooled incidence of recurrent uterine rupture was 10% (95% CI 6-17%). Developed countries had a significantly lower uterine rupture recurrence rate than less developed countries (6% vs 15%, P =.04). Year of publication and study size were not significantly associated with recurrent uterine rupture. The mean number of gestational weeks at the time of recurrent uterine rupture was 32.49 (95% CI 29.90-35.08). The mean number of gestational weeks at the time of delivery without recurrent uterine rupture was 35.77 (95% CI 34.95-36.60). The maternal mortality rate was 5% (95% CI 2-11%), and the neonatal mortality rate was 5% (95% CI 3-10%). Morbidity from hemorrhage, such as bleeding and transfusion, was not reported in any study and could not be evaluated. CONCLUSION: This systematic review estimated a 10% incidence of recurrent uterine rupture. This finding will enable appropriate risk counseling in patients with prior uterine rupture. SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42023395010.

    DOI: 10.1097/AOG.0000000000005418

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  • Comparison of maternal outcomes and clinical characteristics of prenatally- versus non-prenatally-diagnosed placenta accreta spectrum: a systematic review and meta-analysis. International journal

    Shunya Sugai, Kaoru Yamawaki, Tomoyuki Sekizuka, Kazufumi Haino, Kosuke Yoshihara, Koji Nishijima

    American journal of obstetrics & gynecology MFM   101197 - 101197   2023.10

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    OBJECTIVE: To compare maternal outcomes of prenatally- and non-prenatally-diagnosed placenta accreta spectrum (PAS). DATA SOURCES: A systematic literature search was performed in PubMed, the Cochrane database, and Web of Science until 28 November 2022. STUDY ELIGIBILITY CRITERIA: Studies comparing the clinical presentation of prenatally- and non-prenatally-diagnosed PAS were included. Primary outcomes were emergent cesarean delivery, hysterectomy, blood loss volume, number of transfused blood product units, urological injury, coagulopathy, reoperation, intensive care unit admission, and maternal death. We also calculated the pooled mean values for blood loss volume and the number of transfused blood product units. Secondary outcomes comprised maternal age, gestational age at birth, nulliparity, prior cesarean delivery, prior uterine procedure, assisted reproductive technology, placenta increta/percreta, and placenta previa. STUDY APPRAISAL AND SYNTHESIS METHODS: Study screening was conducted after duplicates were identified and removed. The quality of each study and the publication bias were assessed. Forest plots and I2 statistics were calculated for each study outcome for each group. The main analysis was a random-effects analysis. RESULTS: 415 abstracts and 157 full-text studies were evaluated. Thirty-one studies were analyzed. Prenatally-diagnosed PAS was associated with a significantly lower rate of emergency cesarean delivery (odds ratio (OR), 0.37; 95% CI, 0.21-0.67), higher hysterectomy rate (OR, 1.98; 95% CI, 1.02-3.83), lower blood loss volume (mean difference, -0.65; 95% CI, -1.17 to -0.13), and lower number of transfused red blood cell units (mean difference, -1.96; 95% CI, -3.25 to -0.68) compared with non-prenatally-diagnosed PAS. Pooled mean values for blood loss volume and the number of transfused blood product units tended to be lower in the prenatally- vs non-prenatally-diagnosed PAS groups. Nulliparity (OR, 0.14; 95% CI, 0.10-0.20), prior cesarean delivery (OR, 6.81; 95% CI, 4.12-11.25), assisted reproductive technology (OR, 0.19; 95% CI, 0.06-0.61), placenta increta/percreta (OR, 3.97; 95% CI, 2.24- 7.03), and placenta previa (OR, 6.81; 95% CI, 4.12-11.25) showed statistical significance. No significance differences were found for the other outcomes. CONCLUSIONS: Despite its severity, the positive impact of prenatally-diagnosed PAS on outcomes underscores the necessity of a prenatal diagnosis. Additionally, the pooled mean values provide a preoperative preparation guideline.

    DOI: 10.1016/j.ajogmf.2023.101197

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  • Pathologically diagnosed placenta accreta spectrum without placenta previa: a systematic review and meta-analysis. International journal

    Shunya Sugai, Kaoru Yamawaki, Tomoyuki Sekizuka, Kazufumi Haino, Kosuke Yoshihara, Koji Nishijima

    American journal of obstetrics & gynecology MFM   101027 - 101027   2023.5

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    OBJECTIVE: We aimed to conduct a systematic review and meta-analysis to assess clinical characteristics related to pathologically proven placenta accreta spectrum (PAS) without placenta previa. DATA SOURCES: A literature search of PubMed, the Cochrane database, and Web of Science was performed from inception to September 7, 2022. STUDY ELIGIBILITY CRITERIA: The primary outcomes were invasive placenta (including increta or percreta), blood loss, hysterectomy, and antenatal diagnosis. Additionally, maternal age, assisted reproductive technology, previous cesarean section, and previous uterine procedures were investigated as potential risk factors. The inclusion criteria were studies evaluating the clinical presentation of pathologically diagnosed PAS without placenta previa. STUDY APPRAISAL AND SYNTHESIS METHODS: Study screening was conducted after duplicates were identified and removed. The quality of each study and the publication bias were assessed. Forest plots and I2 statistics were calculated for each study outcome for each group. The main analysis was a random-effects analysis. RESULTS: Among 2598 studies that were initially retrieved, five were included in the review. With the exception of one study, four studies could be included in the meta-analysis. This meta-analysis showed that PAS without placenta previa was associated with a less risk of invasive placenta (OR, 0.24; 95% CI, 0.16-0.37), blood loss (MD, -1.19; 95% CI, -2.09 to -0.28) and hysterectomy (OR, 0.11; 95% CI, 0.02-0.53), and more difficult to diagnose prenatally (OR, 0.13; 95% CI, 0.04-0.45) than PAS with placenta previa. Additionally, assisted reproductive technology and a previous uterine procedure were strong risk factors for PAS without placenta previa, while previous cesarean section was a strong risk factor for PAS with placenta previa. CONCLUSIONS: The differences in clinical aspects of PAS with and without placenta previa need to be understood.

    DOI: 10.1016/j.ajogmf.2023.101027

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  • Obstetrical outcomes of pregnant women 50 years and older compared to those aged 45-49 years: A systematic review and meta-analysis. International journal

    Shunya Sugai, Tomoyuki Sekizuka, Kazufumi Haino, Taro Nonaka, Masayuki Sekine, Kosuke Yoshihara, Koji Nishijima

    The journal of obstetrics and gynaecology research   2023.4

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    AIM: In this review, We compared clinical characteristics of pregnant women aged 50 and older with those aged 45-49. Pregnant women ≥45 years are strongly associated with pregnancy-related complications, such as cesarean section rate, gestational hypertension, gestational diabetes mellitus, and preterm birth. Although pregnant women ≥50 years are considered more high-risk, differences in pregnancy outcomes between those over 45 and 50 years of age are unclear. METHODS: Our source strategy included using PubMed, the Cochrane Central Register of Controlled Trials, and Web of Science databases to include studies published between January 1, 2010 and September 30, 2022. The study population was pregnant women 50 years and older; the control group was pregnant women aged 45-49 years. Primary outcomes were cesarean section, gestational hypertension, gestational diabetes mellitus, and preterm birth. The secondary outcomes were small-for-gestational age, 5-min Apgar score < 7, neonatal intensive care unit admission (as neonatal outcomes), nulliparity, assisted reproductive technology (ART), and multifetal pregnancy (as maternal backgrounds). RESULTS: The incidence of cesarean section, gestational hypertension, and preterm delivery was significantly higher in those 50 years and older; however, significant differences disappeared when pooled analyses were limited to singleton pregnancies. ART was significantly more likely to be used for conception of pregnant women ≥50 years. Infants of women ≥50 years were more likely to be admitted to NICUs. CONCLUSIONS: The differences in outcomes between the two groups are obviously influenced by multiple pregnancies, therefore, reproductive medicine specialists should aim for singleton pregnancies in ART.

    DOI: 10.1111/jog.15662

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  • Pregnancy outcomes at maternal age over 45 years: a systematic review and meta-analysis

    Shunya Sugai, Koji Nishijima, Kazufumi Haino, Kosuke Yoshihara

    American Journal of Obstetrics &amp; Gynecology MFM   5 ( 4 )   100885 - 100885   2023.4

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    DOI: 10.1016/j.ajogmf.2023.100885

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  • 3D-CTが胎児診断に有用であった胎児骨系統疾患の3症例

    斎藤 多佳子, 山脇 芳, 五日市 美奈, 生野 寿史, 吉原 弘祐, 西島 浩二

    新潟産科婦人科学会会誌   117 ( 2 )   45 - 50   2023.3

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  • Unexpected uterine body placenta accreta spectrum with placenta previa in a subsequent pregnancy after uterine artery embolization: a case report. International journal

    Shunya Sugai, Kaoru Yamawaki, Kazufumi Haino, Koji Nishijima

    BMC pregnancy and childbirth   22 ( 1 )   706 - 706   2022.9

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    BACKGROUND: A subsequent pregnancy after uterine artery embolization (UAE) raises several concerns, one of which is placenta accreta spectrum (PAS). Placenta previa is the strongest risk factor for PAS, which is most likely to occur in the lower uterine segment. PAS without placenta previa (i.e., uterine body PAS) is considered relatively rare. CASE PRESENTATION: A 35-year-old woman, gravida 2 para 1, had undergone UAE for postpartum hemorrhage due to uterine atony after vaginal delivery in her previous pregnancy. She developed placenta previa during her subsequent pregnancy and was therefore evaluated for PAS in the lower uterine segment. On the basis of examination findings, we considered PAS to be unlikely. During cesarean section, we found that the placenta was not detached from the uterine body, and the patient was determined to have uterine body PAS. Ultimately, a hysterectomy was performed. CONCLUSIONS: PAS can occur in a subsequent pregnancy after UAE. When a subsequent pregnancy after UAE is accompanied by placenta previa, it is important to maintain a high index of suspicion of uterine body PAS without being misled by the presence of placenta previa.

    DOI: 10.1186/s12884-022-05031-0

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  • Spontaneous healing of uterine rupture causing postpartum hemorrhage. International journal

    Shunya Sugai, Kazufumi Haino, Kaoru Yamawaki, Koji Nishijima, Takayuki Enomoto

    European journal of obstetrics, gynecology, and reproductive biology   274   255 - 257   2022.7

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  • Challenges facing workstyle reform for Japanese obstetricians and gynecologists revealed from time studies. International journal

    Masayuki Sekine, Koji Nishijima, Satoshi Nakagawa, Yukio Suzuki, Takashi Murakami, Yasuhito Kato, Takeshi Umazume, Hiroaki Tanaka, Hiroaki Komatsu, Koutaro Doi, Kiyonori Miura, Yoshiki Kudo, Nobuya Unno, Tadashi Kimura, Takayuki Enomoto

    The journal of obstetrics and gynaecology research   48 ( 7 )   1580 - 1590   2022.4

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    AIM: We aimed to grasp the actual working hours of Japanese obstetricians and gynecologists (OB/GYN doctors) as accurately as possible, using the same method of the Ministry of Health, Labour, and Welfare (MHLW). METHODS: The time study targeted OB/GYN doctors working at 10 universities nationwide including Niigata University and 21 institutions which take a role of perinatal care in Niigata prefecture. Working hours per week were calculated based on the following categories: regular and overtime work inside the hospital, work outside the hospital, self-improvement, education, research, and others. Data on weekly working hours were converted to yearly data for analyses. RESULTS: A time study of 10 universities nationwide revealed that 30% of doctors work overtime for more than 1860 h even if they do not include on-call shifts in their working hours. In 21 institutions in Niigata, physicians in Niigata University worked more overtime than other hospitals. It became clear that community health care was supported by dispatching physicians working at university. Furthermore, the results of simulations predicted the pessimistic situation of perinatal medical care in Niigata. CONCLUSIONS: Our study showed the possibility to exist much more OB/GYN doctors who work more than 1860 h of overtime work per year than the data presented by the MHLW based on nation-wide survey in 2019. The fact that the working hours at the side jobs had a great influence on the increase in overtime work of physicians in University was the same result as the report of MHLW published in 2021.

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  • Fetal biometric and Doppler measurements following abdominal radical trachelectomy in the second trimester of the pregnancy

    Eiri Shima, Mina Itsukaichi, Kosuke Yoshihara, Tatsuya Ishiguro, Kazufumi Haino, Koji Nishino, Nobumichi Nishikawa, Koji Nishijima, Takayuki Enomoto

    BMC PREGNANCY AND CHILDBIRTH   22 ( 1 )   2022.4

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    DOI: 10.1186/s12884-022-04671-6

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  • Massive ascites due to lupus peritonitis in a patient with pre-eclampsia and systemic lupus erythematosus: a case report. International journal

    Shunya Sugai, Kazuaki Suda, Kana Tamegai, Kazufumi Haino, Takeshi Nakatsue, Ichiei Narita, Takayuki Enomoto, Koji Nishijima

    BMC pregnancy and childbirth   22 ( 1 )   203 - 203   2022.3

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    BACKGROUND: Patients with systemic lupus erythematosus (SLE) are associated with pre-eclampsia. Pre-eclampsia can have systemic manifestations, such as ascites. Lupus peritonitis, a rare condition in patients with SLE, can also cause ascites. CASE PRESENTATION: A 31-year-old woman, primigravida, with SLE had a blood pressure of 170/110 mmHg and proteinuria at 29 weeks of gestation. She was diagnosed with pre-eclampsia. Her blood pressure was stabilized by an antihypertensive drug. At 30 weeks of gestation, a cesarean section was performed for maternal safety because of decreased urine output and massive ascites. Postoperatively, re-accumulation of ascites was observed. On the fourth postoperative day, ascites (approximately 3 L) was discharged from the cesarean section wound. A decrease in serum complement concentrations was observed, and she was diagnosed as having lupus peritonitis. The steroid dose was increased and she recovered well thereafter. CONCLUSIONS: Ascites occurs in pre-eclampsia and SLE, but determining which of these conditions causes ascites can be difficult. However, careful observation is necessary because of the differences in treatment of these two conditions.

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  • 【産婦人科 働き方改革へのロードマップ】タイムスタディから浮かび上がる医師の働き方2024年問題

    西島 浩二, 中川 慧, 榎本 隆之

    産婦人科の実際   71 ( 1 )   27 - 32   2022.1

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  • Perinatal management of congenital gastrointestinal atresia: A single center, retrospective study with 52 patients

    IMAI Satoshi, YAMAWAKI Kaoru, HAINO Kazufumi, NISHIJIMA Koji

    Journal of Japan Society of Perinatal and Neonatal Medicine   58 ( 3 )   510 - 515   2022

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    We conducted a retrospective analysis on the clinical backgrounds and patient outcomes of 52 cases of congenital gastrointestinal atresia encountered in our institution in the past 28 years. These cases were divided into three groups: esophageal, duodenal, and intestinal atresia. Our evaluation revealed that the rate of polyhydramnios was significantly lower in the intestinal atresia group, but there was no significant difference in the rate of threatened preterm labor or preterm birth among all groups. Esophageal atresia had the highest perinatal mortality rate and the poorest neonatal prognosis. Conversely, there were no reported cases of chromosomal abnormalities in the intestinal atresia group, which had a good prognosis. Collectively, the prenatal diagnosis rate was 77% for all cases. Polyhydramnios as observed on ultrasonography, along with the appearance of gastric bubbles and bowel dilatation, and the use of fetal MRI all contributed to the prenatal diagnosis. However, when compared among groups, prenatal diagnosis and the accuracy of diagnostic rates by fetal MRI were significantly lower for esophageal atresia. Our analysis showed that ultrasonography and fetal MRI are useful tools for prenatal diagnosis of congenital gastrointestinal atresia, even though diagnosis is challenging in some cases. Since prenatal or postnatal prognosis depends on the site of the gastrointestinal tract obstruction, prenatal diagnosis has the significance of providing appropriate information to expectant parents, managing pregnancy, and facilitating neonatal treatment.

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  • Neonatal respiratory disorders and lamellar body counts at 36-38 weeks of gestation

    Matsumoto Kensuke, Sekizuka Tomoyuki, Yamawaki Kaoru, Haino Kazufumi, Tanaka Masato, Nirei Jun, Kobayashi Akira, Nishijima Koji

    Journal of Japan Society of Perinatal and Neonatal Medicine   58 ( 3 )   492 - 497   2022

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    Lamellar body is a surfactant-containing lamellar structure secreted from type II alveolar epithelial cells, and Lamellar body count(LBC)is used to estimate surfactant production in utero and to predict fetal lung maturity. We conducted this study to evaluate the neonatal respiratory status at 36-38 weeks of gestation using LBC. 127 Amniotic fluid were analyzed immediately with no centrifugation and the number of lamellar bodies was counted using a platelet channel on the Sysmex KX-21.12 neonates(9.4%)had respiratory disorders and 115(90.4%) did not. The LBC in respiratory disorders group was significantly lower than in control group(2.7×10<sup>4</sup>/μL vs. 6.0×10<sup>4</sup>/μL; p<0.001). The optimal cut off value to predict neonatal respiratory disorders was 4.4×10<sup>4</sup>/μL(area under the curve 0.833, 95% confidence interval 0.702-0.963), with a sensitivity of 91.7%, specificity 69.6%, positive predictive value 26.2% and negative predictive value 94.1%. The LBC in vaginal delivery cases was significantly higher than in caesarean section cases(8.0×10<sup>4</sup>/μL vs. 5.3×10<sup>4</sup>/μL; p=0.036). LBC is a useful method that is very simple, rapid, objective, and accurate in detecting neonatal respiratory disorders cases.

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  • A retrospective comparative study of the usefulness of dinoprostone vaginal insert and mechanical methods in cervical ripening

    TONOUCHI Eriko, YAMAWAKI Kaoru, HAINO Kazufumi, NISHIJIMA Koji

    Journal of Japan Society of Perinatal and Neonatal Medicine   58 ( 3 )   498 - 503   2022

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    The clinical outcomes of dinoprostone vaginal insert and mechanical methods for cervical ripening were compared retrospectively. The duration of labor and the time taken for hospital discharge were significantly shorter in the vaginal group than in the mechanical group. Mothers in the vaginal group had a significantly higher percentage of deliveries within 24 hours of vaginal insertion of dinoprostone than those in the mechanical group. In cases in which labor was induced at 37 or 38 weeks’ gestation due to maternal complications, there were no cases in either group in which use was discontinued due to worsening complications. Moreover, the time taken for hospital discharge was significantly shorter in the vaginal group, indicating the usefulness of dinoprostone vaginal insert in patients with maternal complications. On the other hand, uterine tachysystole and fetal dysfunctions may occur while administering dinoprostone vaginal inserts; therefore, careful management and compliance with the directions for use is necessary.

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  • Successful repeated uterine artery embolization in postpartum hemorrhage with disseminated intravascular coagulation: a case report and literature review

    Shunya Sugai, Taro Nonaka, Kana Tamegai, Tatsuhiko Sato, Kazufumi Haino, Takayuki Enomoto, Koji Nishijima

    BMC Pregnancy and Childbirth   21 ( 1 )   2021.12

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    DOI: 10.1186/s12884-021-04191-9

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  • A successfully treated case of an acute presentation of congenital thrombotic thrombocytopenic purpura (Upshaw–Schulman syndrome) with decreased ADAMTS13 during late stage of pregnancy

    Taro Nonaka, Masayuki Yamaguchi, Koji Nishijima, Masato Moriyama, Koichi Takakuwa, Takayuki Enomoto

    Journal of Obstetrics and Gynaecology Research   47 ( 5 )   1892 - 1897   2021.5

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    DOI: 10.1111/jog.14737

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  • Attitudes toward overtime work and self-training: A survey on obstetricians and gynecologists in Japan. International journal

    Michinori Mayama, Masayuki Sekine, Yohei Onodera, Tokumasa Suemitsu, Yuto Maeda, Kazutoshi Nakano, Yosuke Sugita, Jumpei Ogura, Takuma Ohsuga, Chisato Kodera, Takashi Murakami, Michiko Kido, Yukio Suzuki, Ayako Shibata, Koji Nishijima, Takeshi Umazume, Satoshi Nakagawa, Nobuya Unno, Hiroaki Komatsu, Makio Shozu, Takayuki Enomoto, Hidemichi Watari

    The journal of obstetrics and gynaecology research   47 ( 5 )   1666 - 1674   2021.5

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    AIM: The Ministry of Health, Labour, and Welfare of Japan proposed a regulation of overtime work as a reform in work style. However, the regulation may deteriorate the quality of medical services due to the reduction in training time. Thus, the study aimed to reveal perceptions in terms of generation gaps in views on self-training and overtime work, among members of the Japan Society of Obstetrics and Gynecology (JSOG). METHODS: A web-based, self-administered questionnaire survey was conducted among members of the JSOG. In total, 1256 respondents were included in the analysis. Data were collected on age, sex, experience as a medical doctor, location of workplace, work style, the type of main workplace, and number of full-time doctors in the main workplace. The study examined the attitudes of the respondents toward overtime work and self-training. The respondents were categorized based on experience as a medical doctor. RESULTS: According to years of experience, 112 (8.9%), 226 (18.0%), 383 (30.5%), 535 (42.6%) doctors have been working for ≤5, 6-10, 11-19, and ≥ 20 years, respectively. Although 54.5% of doctors with ≤5 years of experience expected the regulation on working hours to improve the quality of medical services, those with ≥20 years of experience expressed potential deterioration. After adjusting for covariates, more years of experience were significantly related with the expectation of deterioration in the quality of medical services. CONCLUSIONS: The study revealed a generation gap in the views about self-training and overtime work among obstetricians and gynecologists in Japan.

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  • Noninvasive positive-pressure ventilation in pregnancy to treat acute pulmonary edema induced by tocolytic agents: a case report

    Kotaro Takahashi, Koji Nishijima, Masayuki Yamaguchi, Kensuke Matsumoto, Shunya Sugai, Takayuki Enomoto

    Journal of Medical Case Reports   15 ( 1 )   2021.3

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    Abstract

    Background

    We report a case of pulmonary edema induced by tocolytic agents that was successfully managed with noninvasive positive-pressure ventilation (NPPV) and resulted in extended gestation.

    Case presentation

    A 36-year-old Japanese pregnant woman received tocolytic therapy with ritodrine hydrochloride, magnesium sulfate, nifedipine, and betamethasone from 28 weeks of gestation. She developed respiratory failure. and her chest X-ray showed enlarged pulmonary vascular shadows. At 29 weeks and 1 day of gestation, she was diagnosed with pulmonary edema induced by tocolytic agents. Because respiratory failure worsened 2 days after ritodrine hydrochloride and magnesium sulfate were stopped, NPPV was initiated. Her respiratory status improved and she was weaned off of NPPV after 3 days. She underwent cesarean section because of breech presentation at 30 weeks and 0 days of gestation due to initiation of labor pains.

    Conclusions

    NPPV can be safely administered in cases of tocolytic agent-induced pulmonary edema during pregnancy.

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  • Minimizing abdominal incision for transverse uterine fundal incision by aspiration of amniotic fluid and reduction of uterine size

    Satoshi Nakago, Hiroki Kato, Takashi Shibata, Koji Nishijima, Fumikazu Kotsuji

    Journal of Obstetrics and Gynaecology Research   47 ( 3 )   900 - 903   2021.3

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    DOI: 10.1111/jog.14604

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  • 妊娠子宮破裂と診断された5症例

    為我井 加菜, 須田 一暁, 関根 正幸, 小林 琢也, 廣川 哲太郎, 長谷川 順紀, 奈良本 葉月, 山脇 芳, 南川 高廣, 能仲 太郎, 五日市 美奈, 西島 浩二, 榎本 隆之

    新潟産科婦人科学会会誌   115 ( 2 )   75 - 80   2021.3

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  • 潜伏梅毒合併妊娠の一例

    松本 賢典, 関塚 智之, 能仲 太郎, 西島 浩二, 榎本 隆之, 桑原 春洋, 相澤 悠太

    新潟産科婦人科学会会誌   115 ( 1 )   12 - 14   2021.1

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  • 潜伏梅毒合併妊娠の一例

    松本 賢典, 関塚 智之, 能仲 太郎, 西島 浩二, 榎本 隆之, 桑原 春洋, 相澤 悠太

    新潟産科婦人科学会会誌   115 ( 1 )   12 - 14   2021.1

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  • Factor Structure and Measurement Invariance of the Hospital Anxiety and Depression Scale Across the Peripartum Period Among Pregnant Japanese Women. Reviewed International journal

    Maki Ogawa, Yuichiro Watanabe, Takaharu Motegi, Naoki Fukui, Koyo Hashijiri, Ryusuke Tsuboya, Takuro Sugai, Jun Egawa, Rie Araki, Kazufumi Haino, Masayuki Yamaguchi, Koji Nishijima, Takayuki Enomoto, Toshiyuki Someya

    Neuropsychiatric disease and treatment   17   221 - 227   2021

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    Purpose: The Hospital Anxiety and Depression Scale (HADS) is a self-report questionnaire widely used to assess anxiety and depression. To the best of our knowledge, only four studies have examined the factor structure of the HADS for assessing pregnant women, with conflicting results. This study aimed to assess the factor structure and measurement invariance of the HADS for use with pregnant Japanese women. Participants and Methods: A total of 936 pregnant Japanese women completed the HADS questionnaire at three time points: the first and third trimester of pregnancy, and postpartum. We examined the factor structure of the HADS in Group 1 (n = 466) using exploratory factor analysis (EFA). We then compared the models identified in Group 1 with those from previous studies using confirmatory factor analysis (CFA) in Group 2 (n = 470). We performed multiple-group CFA for Group 2 to test the measurement invariance of the best-fit model across the three time points. Results: The EFA for the Group 1 data at the three time points revealed a two-factor model. In the CFA, the two-factor model from Group 1 showed the best fit with the data at the three time points. In the multiple-group CFA for Group 2, we confirmed the configural and metric invariance of the two-factor model across the three time points. Conclusion: Our findings provide evidence for a two-factor structure and weak measurement invariance of the HADS in pregnant Japanese women during the peripartum period.

    DOI: 10.2147/NDT.S294918

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  • Depression, Anxiety and Primiparity are Negatively Associated with Mother-Infant Bonding in Japanese Mothers. Reviewed International journal

    Takaharu Motegi, Yuichiro Watanabe, Naoki Fukui, Maki Ogawa, Koyo Hashijiri, Ryusuke Tsuboya, Takuro Sugai, Jun Egawa, Rie Araki, Kazufumi Haino, Masayuki Yamaguchi, Koji Nishijima, Takayuki Enomoto, Toshiyuki Someya

    Neuropsychiatric disease and treatment   16   3117 - 3122   2020

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    Purpose: Postpartum depression is a well-known risk factor, and postpartum anxiety and parity are potential risk factors, for mother-infant bonding disorder. However, few studies have focused on the relationships among these factors and mother-infant bonding. This cross-sectional study explored the associations between depression, anxiety and parity, and mother-infant bonding. Materials and Methods: Japanese mothers, both primiparas and multiparas, completed the Mother-to-Infant Bonding Scale (MIBS) and the Hospital Anxiety and Depression Scale (HADS) one month after childbirth. We performed a stepwise multiple regression analysis with the forward selection method to assess the effects of HADS anxiety and depression scores and parity as independent variables on mother-infant bonding as the dependent variable. Results: A total of 2379 Japanese mothers (1116 primiparas and 1263 multiparas) took part in the study. MIBS score (2.89 ± 2.68 vs 1.60 ± 2.11; p < 0.0001) was significantly higher in primiparas than in multiparas. HADS anxiety (6.55 ± 4.06 vs 4.63 ± 3.41; p < 0.0001) and depression (6.56 ± 3.43 vs 5.98 ± 3.20; p < 0.0001) scores were also significantly higher in primiparas than in multiparas. A stepwise multiple regression analysis with the forward selection method revealed that HADS depression and anxiety scores and parity were significantly associated with MIBS score (p = 0.003, 0.015 and 0.023). Conclusion: Depression, anxiety and primiparity were negatively associated with mother-infant bonding one month after childbirth.

    DOI: 10.2147/NDT.S287036

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  • A delayed diagnosis of acute myeloid leukaemia during pregnancy using an old blood cell analyser. Reviewed International journal

    Inoue D, Nishijima K, Takahashi J, Yoshida Y

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology   39 ( 8 )   1173 - 1174   2019.11

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    DOI: 10.1080/01443615.2019.1600480

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  • 5.帝王切開③前置胎盤・癒着胎盤時の帝王切開 Reviewed

    西島 浩二

    周産期医学   2019.10

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  • Biology of the vernix caseosa: A review. Reviewed International journal

    Nishijima K, Yoneda M, Hirai T, Takakuwa K, Enomoto T

    The journal of obstetrics and gynaecology research   45 ( 11 )   2145 - 2149   2019.9

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    The vernix caseosa is a complex membranous structure comprising 80% water, 10% protein, and 10% lipids including barrier lipids such as ceramides, free fatty acids, phospholipids and cholesterol, synthesized partly by fetal sebaceous glands during the last trimester of pregnancy in an antero-posterior and dorsoventral manner. Because of its lipid content, vernix is hydrophobic and protects the skin from excessive water exposure during the development of the stratum corneum. The vernix caseosa has various functions during fetal transition from an intrauterine to an extrauterine environment, including lubrication of the birth canal during parturition, barrier function to prevent water loss, temperature regulation, for innate immunity and for intestinal development. This review discusses the evidence supporting the prenatal and postnatal functions of vernix caseosa, along with its structure, composition, and physical and biological characteristics. Understanding the biology of the vernix may facilitate improved care of preterm infants immediately post-partum.

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  • 著明な絨毛間腔の拡張(Placental lake)を伴う胎盤肥厚を妊娠後期に認めた1例

    西村 俊哉, 西島 浩二, 吉田 好雄

    産婦人科の実際   68 ( 6 )   659 - 663   2019.6

  • 帝王切開術後子宮創部膿瘍の予防戦略 閉鎖式吸引ドレナージ法の有用性

    佐藤 久美子, 西島 浩二, 山本 真, 玉村 千代, 吉田 好雄

    日本周産期・新生児医学会雑誌   55 ( 1 )   33 - 40   2019.5

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  • Prenatal progressive cardiomegaly and functional pulmonary atresia on one fetus of monochorionic diamniotic twin pregnancy regardless of spontaneous resolution of isolated polyhydramnios. Reviewed International journal

    Kawamura H, Nishijima K, Fujii K, Tamura S, Takahashi J, Yoshida Y

    Taiwanese Journal of Obstetrics and Gynecology   58 ( 1 )   51 - 52   2019.1

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    DOI: 10.1016/j.tjog.2018.11.009

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  • オウム病による国内初の妊産婦死亡例

    清水 可奈子, 西島 浩二, 河原 和美, 坂野 陽通, 吉村 芳修, 柳原 格, 今村 好章, 黒川 哲司, 吉田 好雄

    産婦人科の実際   67 ( 4 )   445 - 450   2018.4

  • 妊娠第2三半期における無症候性子宮頸管長短縮の発見時期と妊娠予後に関する検討

    川村 裕士, 西島 浩二, 玉村 千代, 高橋 仁, 折坂 誠, 吉田 好雄

    超音波医学   45 ( Suppl. )   S721 - S721   2018.4

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  • Primary intramedullary spinal cord tumour in pregnancy: a case report. Reviewed International journal

    Fujii K, Orisaka M, Yamamoto M, Nishijima K, Yoshida Y

    Spinal Cord Ser Cases   4 ( 25 )   25 - 25   2018.3

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    Introduction: Primary spinal cord tumours can lead to severe neurological complications and even death. Pregnant women often complain of discomfort of the lower limbs, which is usually caused by sciatica. Here we present the case of a pregnant woman, who was initially considered to have sciatica, but was finally diagnosed with a primary intramedullary spinal cord tumour. Case presentation: A 28-year-old pregnant woman presented to our hospital with inexplicable numbness in her lower limbs. She was initially considered to have sciatica, but acute deterioration of neurological symptoms and plain magnetic resonance imaging (MRI) findings suggested malignancy. The patient was finally diagnosed with a primary intramedullary spinal cord tumour at the C3-Th5 region. An emergency caesarean section was performed, after which the spinal cord lesion was evaluated using contrast-enhanced MRI, positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-d-glucose integrated with computed tomography, and spinal angiography, and further treatment was initiated. However, while the patient's spinal cord tumour surgery was performed in early postpartum, her paraplegia and bladder and rectal disturbances remained unchanged even 1 year after surgery. Discussion: Because of the low incidence of spinal cord tumours during pregnancy, no definite reports have been published on the treatment of pregnant patients with spinal cord tumours. Although safe imaging tests during pregnancy are limited, intervention in such patients should be performed as early as possible to avoid irreversible neurological deterioration.

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  • Re: Transverse uterine fundal incision for placenta praevia with accreta, involving the entire anterior uterine wall: a case series. Spontaneous uterine rupture during the subsequent pregnancy after transverse uterine fundal incision for placenta praevia with accreta Reviewed

    Sayaka Fujiwara-Arikura, Koji Nishijima, Chiyo Tamamura, Yukiko Nishikawa, Jin Takahashi, Hiroshi Kawamura, Satoshi Nakago, Fumikazu Kotsuji, Yoshio Yoshida

    BJOG: An International Journal of Obstetrics and Gynaecology   125 ( 3 )   389 - 390   2018.2

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    DOI: 10.1111/1471-0528.14899

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  • Intrauterine fetal death caused by seatbelt injury Reviewed

    Shizuka Yamada, Koji Nishijima, Jin Takahashi, Nozomu Takahashi, Chiyo Tamamura, Yoshio Yoshida

    TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY   56 ( 4 )   558 - 560   2017.8

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    DOI: 10.1016/j.tjog.2016.08.009

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  • 神経線維腫症I型(レックリングハウゼン病)合併妊娠の周産期管理 3症例の経験を経て

    天谷 優介, 玉村 千代, 西島 浩二, 井上 大輔, 高橋 望, 加藤 加奈, 津吉 秀昭, 高橋 仁, 吉田 好雄

    産婦人科の実際   65 ( 13 )   1795 - 1799   2016.12

  • 【周産期医学必修知識第8版】産科編 前置胎盤・癒着胎盤

    西島 浩二, 吉田 好雄

    周産期医学   46 ( 増刊 )   258 - 262   2016.12

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  • 子宮内感染例の帝切後の創離開対策 修復・摘出・経過観察 9症例の経験から

    加藤 大樹, 柴田 貴司, 徳田 妃里, 松木 理薫子, 小寺 知揮, 中後 聡, 大石 哲也, 小辻 文和, 西島 浩二, 吉田 好雄

    産婦人科手術   ( 27 )   153 - 153   2016.6

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  • 子宮内感染例の帝切後の子宮創離開への対策 創修復・子宮摘出・1年後の修復 10症例の経験から

    加藤 大樹, 柴田 貴司, 徳田 妃里, 松木 理薫子, 中後 聡, 大石 哲也, 小辻 文和, 吉田 好雄, 西島 浩二

    日本周産期・新生児医学会雑誌   52 ( 2 )   616 - 616   2016.6

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  • 羊水過多を呈した妊婦に対し、問診を契機に筋強直性ジストロフィーと診断しえた2症例

    坂野 陽通, 河原 和美, 佐藤 久美子, 高橋 仁, 西島 浩二, 吉田 好雄

    産科と婦人科   83 ( 4 )   451 - 454   2016.4

  • Hemophagocytic lymphohistiocytosis caused by pyogenic liver abscess during pregnancy:a case report and literature review. Reviewed

    西島 浩二

    Open Journal of Obstetrics and Gynecology (OJOG)   6 ( 5 )   287 - 292   2016.4

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  • 急性白血病合併妊娠の管理における産婦人科の役割

    井上 大輔, 西島 浩二, 山本 真, 高橋 仁, 知野 陽子, 福田 真, 折坂 誠, 黒川 哲司, 吉田 好雄

    産婦人科の実際   65 ( 2 )   213 - 217   2016.2

  • シートベルト外傷により子宮内胎児死亡に至った1例

    山田 しず佳, 服部 由香, 西島 浩二, 高橋 仁, 折坂 誠, 吉田 好雄

    周産期医学   46 ( 1 )   125 - 128   2016.1

  • Re: Transverse uterine fundal incision for placenta praevia with accreta, involving the entire anterior uterine wall: a case series How to reduce overuse of the new method for dealing with placenta praevia suggested by Kotsuji et al. Reply Reviewed

    Koji Nishijima, Makoto Orisaka, Jin Takahashi, Makoto Yamamoto, Satoshi Nakago, Atsushi Yoshida, Hideaki Masuzaki, Fumikazu Kotsuji, Yoshio Yoshida

    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY   122 ( 13 )   1844 - 1845   2015.12

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  • 海外文献から:Clinical Expert Series 後方後頭位の分娩管理 Reviewed

    西島 浩二

    産婦人科の実際.   64 ( 6 )   836   2015.6

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  • 海外文献から:慢性高血圧と先天奇形の発症リスクに関するコホート研究 Reviewed

    西島 浩二

    産婦人科の実際.   64 ( 4 )   580   2015.4

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  • Authors' reply: Transverse uterine fundal incision in placenta praevia with possible placenta accreta: a last resort Reviewed

    Nishijima K, Takahashi J, Orisaka M, Kurokawa T, Tamamura C, Yoshida A, Masuzaki H, Sekiya T, Yoshida Y, Kotsuji F

    BJOG   122 ( 3 )   448 - 449   2015.2

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  • 海外文献から:重症新生児脳症に対する胎児心拍モニタリングの診断精度(症例対照研究) Reviewed

    西島 浩二

    産婦人科の実際   64 ( 1 )   118   2015.1

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  • Amniotic Fluid Embolism Triggered By Hypertensive Crisis Due to Undiagnosed Pheochromocytoma in a Pregnant Subject With Neurofibromatosis Type 1 Reviewed

    NISHIJIMA Koji

    AACE Clinical Case Rep   1 ( 3 )   178 - 181   2015

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  • 【最新版 新生児慢性肺疾患】胎児・新生児期の呼吸器系の発達

    西島 浩二, 吉田 好雄

    周産期医学   44 ( 8 )   1003 - 1006   2014.8

  • Transverse uterine fundal incision for placenta praevia with accreta Reply Reviewed

    K. Nishijima, Y. Yoshida, F. Kotsuji

    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY   121 ( 6 )   769 - 770   2014.5

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  • Authors' reply: transverse uterine fundal incision in placenta praevia with possible placenta accrete Reviewed

    Nishijima K, Yoshida Y, Kotsuji F

    BJOG   121 ( 6 )   771 - 772   2014.5

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  • 子宮体下部〜峡部の側壁を縦走する非瘢痕子宮破裂の4症例

    白藤 文, 黒川 哲司, 鈴木 秀文, 折坂 誠, 西島 浩二, 品川 明子, 高橋 望, 岡 秀明, 山本 宝, 吉田 好雄

    産科と婦人科   81 ( 2 )   271 - 275   2014.2

  • Necessity of antihypertensive therapy with alpha-methyldopa for pregnant women with hypertensive disorders after 36 weeks of gestation Reviewed

    Daigaku Kayashi, Koji Nishijima, Ikuko Uchinami, Jin Takahashi, Hideaki Tsuyoshi, Kumiko Sato, Makoto Orisaka, Yoshio Yoshida

    Medicinski Glasnik   11 ( 1 )   246 - 247   2014.2

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  • Authors' reply: Placenta praevia accreta Reviewed

    K. Nishijima, Y. Yoshida, F. Kotsuji

    BJOG: An International Journal of Obstetrics and Gynaecology   121 ( 6 )   773 - 775   2014

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    DOI: 10.1111/1471-0528.12555

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  • Fructose-1,6-bisphosphatase deficiency: a case of a successful pregnancy by closely monitoring metabolic control. Reviewed International journal

    Sugita G, Tsuyoshi H, Nishijima K, Yoshida Y

    JIMD reports   14   115 - 118   2014

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    In patients with fructose-1,6-bisphosphatase (FBPase) deficiency, maternal and fetal neurodevelopmental abnormalities can be induced by severe hypoglycemia and lactic acidosis, which is triggered by pregnancy. The patient was a 24-year-old and primipara. Via pre-pregnancy education and management including self-monitoring of blood glucose and prompt medical intervention with glucose infusions, she never experienced hypoglycemia with impaired consciousness. She delivered a 2,406 g male infant at 38 weeks of gestation by cesarean section. No neurological abnormalities in either the mother or the child appeared during the following 2 years. This is the first report with detailed descriptions of the management of a pregnant woman with FDPase deficiency. This report suggests that for a patient with FBPase deficiency, the maternal and fetal complications can be reduced by pre-pregnancy education and self-monitoring of blood glucose to prevent hypoglycemia.

    DOI: 10.1007/8904_2013_290

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  • Transverse uterine fundal incision for placenta praevia with accreta, involving the entire anterior uterine wall: a case series Reviewed

    F. Kotsuji, K. Nishijima, T. Kurokawa, Y. Yoshida, T. Sekiya, M. Banzai, H. Minakami, Y. Udagawa

    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY   120 ( 9 )   1144 - 1149   2013.8

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    DOI: 10.1111/1471-0528.12252

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  • 【前置胎盤/前置癒着胎盤-早期診断、早期介入、安全な手術は?】分娩管理 帝王切開の工夫 子宮底部横切開法

    西島 浩二, 吉田 好雄, 小辻 文和

    周産期医学   43 ( 6 )   737 - 743   2013.6

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  • Management of drug-induced hyperbilirubinaemia in early pregnancy Reviewed

    H. Tsuyoshi, K. Nishijima, J. Takahashi, Y. Yoshida

    South African Journal of Obstetrics and Gynaecology   19 ( 1 )   22 - 23   2013

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    DOI: 10.7196/SAJOG.580

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  • Interactions among pulmonary surfactant, vernix caseosa, and intestinal enterocytes: intra-amniotic administration of fluorescently liposomes to pregnant rabbits Reviewed

    Koji Nishijima, Ken-ichi Shukunami, Hideo Yoshinari, Jin Takahashi, Hideyuki Maeda, Hitoshi Takagi, Fumikazu Kotsuji

    AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY   303 ( 3 )   L208 - L214   2012.8

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    DOI: 10.1152/ajplung.00081.2011

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  • Patient with neonatal-onset chronic hepatitis presenting with mevalonate kinase deficiency with a novel MVK gene mutation Reviewed

    Masahiro Tahara, Hidemasa Sakai, Ryuta Nishikomori, Takahiro Yasumi, Toshio Heike, Ikuo Nagata, Ayano Inui, Tomoo Fujisawa, Yosuke Shigematsu, Koji Nishijima, Katsuji Kuwakado, Shinichi Watabe, Junji Kameyama

    MODERN RHEUMATOLOGY   21 ( 6 )   641 - 645   2011.12

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    DOI: 10.1007/s10165-011-0442-7

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  • Catastrophic Progression of Preterm Delivery Caused by 2009 H1N1 Influenza Infection Reviewed

    Koji Nishijima, Tetsuji Kurokawa, Akiko Shinagawa, Ikuko Uchinami, Hideaki Tsuyoshi, Fumikazu Kotsuji

    JOURNAL OF EMERGENCY NURSING   37 ( 5 )   435 - 436   2011.9

  • 50症例の経験から「子宮底部横切開による帝切法」の有用性と問題点を考える 前置癒着胎盤に対する安全な手術法の確立を目指して

    西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄, 小辻 文和, 水上 尚典, 斉藤 豪, 遠藤 俊明, 阪西 通夫, 宇田川 康博, 関谷 隆夫

    産婦人科手術   ( 22 )   171 - 171   2011.8

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  • 広範囲な穿通胎盤症例の膀胱温存法 病的膀胱の修復とカテーテル留置による膀胱摘出の回避

    西島 浩二, 高橋 仁, 山本 真, 折坂 誠, 黒川 哲司, 吉田 好雄, 小辻 文和, 秋野 裕信, 青木 芳隆

    産婦人科の実際   60 ( 4 )   609 - 613   2011.4

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  • 帝切後子宮縫合不全を修復した後に妊娠、出産となった1症例

    鈴木 秀文, 小辻 文和, 西島 浩二, 山本 宝

    産婦人科手術   ( 21 )   164 - 164   2010.6

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  • 病的膀胱の修復とカテーテル留置により膀胱摘出を回避できた穿通胎盤症例

    小辻 文和, 西島 浩二, 黒川 哲司, 折坂 誠, 吉田 好雄

    産婦人科手術   ( 21 )   164 - 164   2010.6

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  • 帝王切開術 困難症例への対応 反復帝切による腹腔内癒着防止のために 私どもが行う腹膜外帝切とトレーニング法

    黒川 哲司, 西島 浩二, 吉田 好雄, 小辻 文和

    産婦人科手術   ( 21 )   21,47 - 29,47   2010.6

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  • Pregnant woman with gastric pain Reviewed

    Koji Nishijima, Jin Takahashi, Makoto Yamamoto, Makoto Orisaka, Chiyo Suzuki, Hirokazu Tsukahara, Ken-Ichi Shukunami, Tetsuji Kurokawa, Yoshio Yoshida, Fumikazu Kotsuji

    Annals of Emergency Medicine   55 ( 5 )   483 - 490   2010

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    DOI: 10.1016/j.annemergmed.2009.06.506

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  • 動脈管早期閉鎖により新生児遷延性肺高血圧症をきたした1例

    巨田 尚子, 田村 知史, 徳力 周子, 小倉 一将, 畑 郁江, 塚原 宏一, 鈴木 千代, 西島 浩二, 折坂 誠, 小辻 文和, 眞弓 光文

    小児科臨床   61 ( 8 )   1685 - 1689   2008.8

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  • Clinical significance of the balance between the L-arginine/NOS/NO pathway and the PRMT/ADMA/DDAH pathway Invited

    H.Tsukahara, N.Oota, S.Tokuriki, S.Tamura, M.Toyooka, K.Nishijima, M.Orisaka, F.Kotsuji, N.Ohta, H.Kawakami, K.Sekine, H.Nagasaka, M.Mayumi

    Journal of Developmental Nephrology   16 ( 1 )   21-28   2008.7

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  • 【前置癒着胎盤 臨床経験に学ぶ】帝王切開手術法 前置胎盤、低置胎盤、前置血管の帝切法 従来法に「子宮底部横切開法」「子宮下部U字縫合」を組み合わせた治療指針

    小辻 文和, 西島 浩二, 折坂 誠, 田嶋 公久, 吉田 好雄

    産婦人科の実際   57 ( 6 )   989 - 995   2008.6

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  • 新生児骨代謝の評価 特に子宮収縮抑制剤の作用について

    徳力 周子, 塚原 宏一, 古畑 律代, 巨田 尚子, 田村 知史, 畑 郁江, 西島 浩二, 宿南 憲一, 小辻 文和, 眞弓 光文

    小児科臨床   61 ( 5 )   1003 - 1009   2008.5

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  • Determination of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, in umbilical blood Reviewed

    Hirokazu Tsukahara, Naoko Ohta, Shuko Tokuriki, Koji Nishijima, Fumikazu Kotsuji, Hisako Kawakami, Norihito Ohta, Kyouichi Sekine, Hironori Nagasaka, Mitsimi Mayumi

    METABOLISM-CLINICAL AND EXPERIMENTAL   57 ( 2 )   215 - 220   2008.2

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    DOI: 10.1016/j.metabol.2007.09.003

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  • Inclusion and exclusion criteria of preterm premature rupture of membranes Reviewed

    Ken-ichi Shukunami, Koji Nishijima, Fumikazu Kotsuji

    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY   195 ( 4 )   1185 - 1185   2006.10

  • Hepatocyte growth factor concentration in umbilical cord blood Reviewed

    Nishijima K

    Medical Postgraduate   44 ( 4 )   415 - 417   2006.10

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  • Advanced glycation end-product formation from fetus to adolescence: A parameter for evaluating “carbonyl stress” status in humans Reviewed

    Nishijima K

    J Dev Nephrol   4 ( 1 )   42 - 48   2006.9

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  • A benign solitary uterine leiomyoma on the pelvic peritoneum detected long after the hysterectomy for fibroids Reviewed

    K. Shukunami, K. Nishijima, T. Kurokawa, M. Orisaka, Y. Yoshida, F. Kotsuji

    Journal of Obstetrics and Gynaecology   26 ( 6 )   589   2006.8

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    DOI: 10.1080/01443610600636152

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  • Comment to "A prospective population-based study of 598 cases of PPROM between 24 and 35 weeks&apos; gestation: Description, management, and mortality (DOMINOS cohort)" Reviewed

    Ken-ichi Shukunami, Koji Nishijima, Ikuko Uchinami, Kimihisa Tajima, Yoshio Yoshida, Fumikazu Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   127 ( 2 )   274 - 274   2006.8

  • Micelles of pulmonary surfactant in human amniotic fluid at term Reviewed

    Koji Nishijima, Ken-Ichi Shukunami, Hirokazu Tsukahara, Makoto Orisaka, Jun&apos;Ichiro Miura, Fumikazu Kotsuji

    PEDIATRIC RESEARCH   60 ( 2 )   196 - 199   2006.8

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    DOI: 10.1203/01.pdr.0000228329.90502.3a

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  • Comment to "analysis of 59 cases of emergent peripartum hysterectomies during a 13-year period" [1] Reviewed

    Ken-Ichi Shukunami, Koji Nishijima, Fumikazu Kotsuji

    Archives of Gynecology and Obstetrics   274 ( 4 )   255   2006.7

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  • Comment to "Peripartum hysterectomy in a teaching hospital in the eastern region of Turkey" Reviewed

    Ken-ichi Shukunami, Koji Nishijima, Ikuko Uchinami, Kimihisa Tajima, Yoshio Yoshida, Fumikazu Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   127 ( 1 )   137 - 138   2006.7

  • A very low transverse uterine incision Reviewed

    Ken-ichi Shukunami, Makoto Orisaka, Koji Nishijima, Kumiko Yoshii, Toru Senda, Yoshio Yoshida, Fumikazu Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   126 ( 2 )   269 - 270   2006.6

  • プロテインS低下症が原因と考えられた妊娠初期妊婦の深部静脈血栓症の1例 カプロシン皮下注射を用いた周産期管理

    井隼 彰夫, 田中 國義, 上坂 孝彦, 田中 哲文, 森岡 浩一, 山田 就久, 李 偉, 佐々木 正人, 高森 督, 半田 充輝, 田邉 佐和香, 西島 浩二, 打波 郁子, 宿南 憲一, 小辻 文和, 大月 澄

    周産期医学   36 ( 6 )   787 - 790   2006.6

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  • 妊娠初期の胎盤辺縁角測定による妊娠末期の前置胎盤発生予測

    宿南 憲一, 西島 浩二, 黒川 哲司, 打波 郁子, 折坂 誠, 田嶋 公久, 吉田 好雄, 小辻 文和

    産婦人科の実際   55 ( 6 )   1003 - 1006   2006.6

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  • Comment to "seasonal onset of the menopause" Reviewed

    Ken-ichi Shukunami, Koji Nishijima, Fumikazu Kotsuji

    MATURITAS   54 ( 2 )   198 - 198   2006.5

  • 胎児超音波検査でPotter sequenceを疑われ,出生後urosepsisの管理に難渋した多発性嚢胞腎の1女児例

    古畑 律代, 金谷 由宇子, 田村 知史, 徳力 周子, 塚原 宏一, 谷澤 昭彦, 平岡 政弘, 眞弓 光文, 西島 浩二, 宿南 憲一

    Pharma Medica   24 ( 5 )   126 - 129   2006.5

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  • Comment on "Efficient prematurity prevention is possible by pH self-measurement and immediate therapy of threatening ascending infection" Reviewed

    Koji Nishijima, Ken-ichi Shukunami, Fumikazu Kotsuji, Toshihiko Yamano, Yoichi Fukushima, Hisakazu Iino

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   125 ( 1 )   146 - 146   2006.3

  • Rotation abnormality in septate uterus with a double cervix Reviewed

    K Shukunami, K Nishijima, Uchinami, I, Y Yoshida, F Kotsuji

    JOURNAL OF REPRODUCTIVE MEDICINE   51 ( 3 )   218 - 218   2006.3

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  • Comment on &apos;Season of birth influences the timing of menopause&apos; Reviewed

    KI Shukunami, K Nishijima, F Kotsuji

    HUMAN REPRODUCTION   21 ( 2 )   568 - 569   2006.2

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  • Flare-up of serum amylase prior to onset of lethal ketoacidosis in a patient with fulminant type 1 diabetes Reviewed

    J Takahashi, K Nishijima, K Shukunami, A Yakihara, T Senda, Y Yoshida, F Kotsuji

    DIABETES CARE   29 ( 2 )   461 - 462   2006.2

  • Re: "Preterm birth: The interaction of traffic-related air pollution with economic hardship in Los Angeles neighborhoods" Reviewed

    K Shukunami, K Nishijima, F Kotsuji

    AMERICAN JOURNAL OF EPIDEMIOLOGY   163 ( 4 )   392 - 3; author reply 393   2006.2

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  • Re: Use of the Atad catheter for the induction of labour in women who have had a previous Caesarean section: A case series Reviewed

    K Shukunami, K Nishijima, F Kotsuji

    AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY   46 ( 1 )   70 - 70   2006.2

  • Visualization of renal stone using 3-D ultrasound with surface rendering in a pregnant woman Reviewed

    KI Shukunami, K Nishijima, M Miyazaki, H Oka, Y Hattori, F Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   124 ( 1 )   119 - 120   2006.1

  • An intraplacental fluid-fluid level of massive subchorionic hematoma Reviewed

    Naoki Matsudera, Ken-ichi Shukunami, Koji Nishijima, Fumikazu Kotsuji

    FETAL DIAGNOSIS AND THERAPY   21 ( 4 )   400 - 400   2006

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  • When should blood samples be obtained for an appropriate estimation? Reviewed

    Ken-ichi Shukunami, Koji Nishijima, Fumikazu Kotsuji

    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA   85 ( 7 )   894 - 894   2006

  • Endometrial and subendometrial vascularity measurements in patients with intramural uterine fibroids Reviewed

    K Shukanami, K Nishijima, Uchinami, I, K Tajima, Y Yoshida, F Kotsuji

    JOURNAL OF ULTRASOUND IN MEDICINE   24 ( 12 )   1738 - 1738   2005.12

  • Medical vs. surgical management of early pregnancy failure Reviewed

    K Shukunami, K Nishijima, F Kotsuji

    NEW ENGLAND JOURNAL OF MEDICINE   353 ( 22 )   2403 - 2403   2005.12

  • Is gestational week at birth a predictor of schizophrenia? Reviewed

    K Shukunami, K Nishijima, M Shukunami, F Kotsuji

    BRITISH JOURNAL OF PSYCHIATRY   187   589 - 589   2005.12

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  • Location of the uterine transverse incisions in patients with multiple repeat caesarean sections Reviewed

    K Shukunami, K Nishijima, K Tajima, Y Yoshida, F Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   123 ( 1 )   125 - 125   2005.11

  • A useful technique for controlling placental site bleeding for an uncommon type of placentation Reviewed

    K Shukunami, K Nishijima, K Tajima, J Takahashi, Y Yoshida, F Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   122 ( 2 )   247 - 248   2005.10

  • 開腹下癒着胎盤子宮温存手術の工夫

    西島 浩二, 宿南 憲一, 有倉 清香, 田嶋 公久, 吉田 好雄, 小辻 文和

    産婦人科の実際   54 ( 6 )   979 - 982   2005.6

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  • An additional approach of repeat digital examination for preterm labor. Comment on Volumenie et al. [Eur J Obstet Gynecol RB 117 (2004) 33-7] Reviewed

    K Shukunami, K Nishijima, K Tajima, Y Yoshida, F Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   120 ( 1 )   120 - 120   2005.5

  • An operative technique for conservative management of placenta accreta Reviewed

    K Nishijima, K Shukunami, S Arikura, F Kotsuji

    OBSTETRICS AND GYNECOLOGY   105 ( 5 )   1201 - 1203   2005.5

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    DOI: 10.1097/01.AOG.0000154005.24631.ec

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  • Probiotics affects vaginal flora in pregnant women, suggesting the possibility of preventing preterm labor Reviewed

    K Nishijima, K Shukunami, F Kotsuji

    JOURNAL OF CLINICAL GASTROENTEROLOGY   39 ( 5 )   447 - 448   2005.5

  • Leiomyoma originating in the greater omentum Reviewed

    K Shukunami, T Kurokawa, K Nishijima, F Kotsuji

    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY   119 ( 2 )   257 - 257   2005.4

  • Sonographic appearance of previous cesarean scars in pregnant women as 3 macroscopic types Reviewed

    K Shukunami, K Nishijima, Uchinami, I, Y Yoshida, F Kotsuji

    JOURNAL OF ULTRASOUND IN MEDICINE   24 ( 3 )   394 - 395   2005.3

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  • A small-angled thin edge of the placenta predicts abnormal placentation at delivery Reviewed

    K Shukunami, K Nishijima, T Kurokawa, K Tajima, N Kamitani, Y Yoshida, F Kotsuji

    JOURNAL OF ULTRASOUND IN MEDICINE   24 ( 3 )   331 - 335   2005.3

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  • Concentrations of thioredoxin, a redox-regulating protein, in umbilical cord blood and breast milk Reviewed

    Y Todoroki, H Tsukahara, Y Ohshima, K Shukunami, K Nishijima, F Kotsuji, A Hata, K Kasuga, K Sekine, H Nakamura, J Yodoi, M Mayumi

    FREE RADICAL RESEARCH   39 ( 3 )   291 - 297   2005.3

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  • Responses by pregnant Jehovah's witnesses on health care proxies Reviewed

    Shukunami K, Nishijima K, Yoshida Y, Kotsuji F

    OBSTETRICS AND GYNECOLOGY   105 ( 2 )   441 - 441   2005.2

  • Repeat measurement of cervical length after successful tocolysis Reviewed

    K Shukunami, K Nishijima, Y Yoshida, F Kotsuji

    OBSTETRICS AND GYNECOLOGY   105 ( 2 )   443 - 443   2005.2

  • Ruptured interstitial pregnancy caused by inactive chorionic villi presenting with negative serum beta-hCG Reviewed

    K Nishijima, K Shukunami, H Tsuyoshi, Y Hattori, Y Yoshida, F Kotsuji

    AMERICAN JOURNAL OF EMERGENCY MEDICINE   23 ( 1 )   89 - 89   2005.1

  • Management for neonatal aspiration syndrome caused by vernix caseosa Reviewed

    K Nishijima, K Shukunami, S Inoue, F Kotsuji

    FETAL DIAGNOSIS AND THERAPY   20 ( 3 )   194 - 196   2005

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  • Massive subchorionic hematoma: Peculiar prenatal images and review of the literature Reviewed

    K Nishijima, K Shukunami, H Tsuyoshi, M Orisaka, K Tajima, T Kurokawa, Y Yoshida, F Kotsuji

    FETAL DIAGNOSIS AND THERAPY   20 ( 1 )   23 - 26   2005

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    DOI: 10.1159/000081364

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  • Transverse fundal uterine incision in a patient with placenta increta Reviewed

    Ken-Ichi Shukunami, K. Hattori, K. Nishijima, F. Kotsuji

    Journal of Maternal-Fetal and Neonatal Medicine   16 ( 6 )   355 - 356   2004.12

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    DOI: 10.1080/14767050400018189

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  • Recanalization of a fallopian tube after detorsion of twisted adnexa - Report of a case with follow-up by repeat hysterosalpingography Reviewed

    KI Shukunami, K Nishijima, M Orisaka, F Kotsuji

    JOURNAL OF REPRODUCTIVE MEDICINE   49 ( 9 )   756 - 758   2004.9

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  • Unilateral and bilateral multicystic dysplastic kidneys in fetuses Reviewed

    K. Shukunami, K. Nishijima, M. Orisaka, K. Tajima, S. Fukuda, Y. Yoshida, F. Kotsuji

    Journal of Obstetrics and Gynaecology   24 ( 4 )   458 - 459   2004.6

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    DOI: 10.1080/01443610410001696897

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  • Galactocele of the breast in a postmenopausal woman Reviewed

    Ken-Ichi Shukunami, Koji Nishijima, Makoto Orisaka, Kimihisa Tajima, Fumikazu Kotsuji

    Current Surgery   61 ( 3 )   319   2004.5

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    DOI: 10.1016/j.cursur.2003.11.005

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  • Acute abdomen in a Jehovah's Witness with chronic anemia Reviewed

    K Shukunami, K Nishijima, M Orisaka, Y Yoshida, F Kotsuji

    AMERICAN JOURNAL OF EMERGENCY MEDICINE   22 ( 3 )   242 - 243   2004.5

  • Unilateral and bilateral multicystic dysplastic kidneys in fetuses. Reviewed

    Shukunami K, Nishijima K, Orisaka M, Tajima K, Fukuda S, Yoshida Y, Kotsuji F

    J Obstet Gynaeco   2004.1

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  • Acute abdomen in a Jehovah's witness with chronic anemia [14] Reviewed

    Ken-Ichi Shukunami, Koji Nishijima, Makoto Orisaka, Yoshio Yoshida, Fumikazu Kotsuji

    American Journal of Emergency Medicine   22 ( 3 )   242 - 243   2004

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    DOI: 10.1016/j.ajem.2004.02.026

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  • A subamniotic hematoma resembling a deflated balloon Reviewed

    Ken-Ichi Shukunami, Makoto Orisaka, Sanae Orisaka, Koji Nishijima, Kimihisa Tajima, Kenji Goto, Fumikazu Kotsuji

    Journal of Maternal-Fetal and Neonatal Medicine   16 ( 6 )   373 - 375   2004

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    DOI: 10.1080/jmf.16.6.373.375

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  • 切迫早産治療薬の副作用軽減に有効であった桂枝加竜骨牡蠣湯

    宿南 憲一, 西島 浩二, 津吉 秀昭, 折坂 誠, 小辻 文和

    漢方医学   27 ( 4 )   177 - 177   2003.9

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  • Weekly Paclitaxelによる卵巣癌短期入院化学療法 卵巣癌患者のQOL向上のために

    西島 浩二, 福田 真, 吉井 久美子, 澤村 陽子, 金嶋 光夫, 紙谷 尚之, 小辻 文和

    産婦人科治療   83 ( 2 )   231 - 235   2001.8

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    Other Link: http://search.jamas.or.jp/link/ui/2002093375

  • 【チーム医療でとりくむクリニカルパス】 帝王切開術のクリニカルパス Reviewed

    西島 浩二

    消化器外科Nursing   5 ( 12 )   1376 - 1379   2000.1

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  • 正常ヒト子宮内膜細胞の新しい培養法 組織構築の再構成を目ざして Reviewed

    西島 浩二

    産婦人科の世界   41 ( 10 )   879 - 886   1989.10

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Books

  • 産科手術7.帝王切開術 MFICUグリーンノートポケットマニュアル

    西島 浩二

    2019.6 

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  • 帝王切開の強化書-Kaiserを極める- (監修 吉田好雄,編集・執筆 西島浩二)

    西島 浩二

    金原出版  2017.11 

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  • 福井大学病院の得意な治療がわかる本―最高・最新の医療を安心と信頼の下で(編著 福井大学医学部附属病院)

    西島 浩二

    発行:バリューメディカル 発売:図書出版 南々社  2017.8 

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  • 症例から学ぶ 周産期診療ワークブック第2版(編集 一般社団法人日本周産期・新生児医学会教育・研修委員会)

    西島 浩二

    メジカルビュー社  2016.7 

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  • Micelles:Structural Biochemistry, Formation and Functions & Usage(分担執筆:A treatment strategy for the gastrointestinal development of extremely premature infants by administration of micelles derived from pulmonary surfactants and the vernix caseosa in p・・・

    Nova Science Publishers, Inc  2013  ( ISBN:9781629484457

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    Micelles:Structural Biochemistry, Formation and Functions & Usage(分担執筆:A treatment strategy for the gastrointestinal development of extremely premature infants by administration of micelles derived from pulmonary surfactants and the vernix caseosa in pregnant rabbits)

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  • OGS NOW(分担執筆:前置癒着胎盤 子宮底部横切開法-トラブル回避の手術手順と適応-)

    メジカルビュー社  2012 

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  • 福井大学重点研究成果集(分担執筆:超低出生体重児の消化管成熟に向けた治療戦略: 肺サーファクタントを用いた動物実験)

    福井大学  2008 

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  • プロバイオティクス・プレバイオティクス・バイオジェニックス/腸内細菌の関わりを中心としたその研究と意義(分担執筆:尿路感染症. プロバイオティクス・プレバイオティクス・バイオジェニックス:腸内細菌の関わりを中心とした研究とその意義)

    2006 

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MISC

  • 妊娠糖尿病合併妊婦における産後糖代謝異常リスクの検討

    山田 貴穂, 柳生田 紀子, 西島 浩二, 小川 洋平, 谷内 洋子, 吉原 弘祐, 曽根 博仁

    糖尿病と妊娠   23 ( 3 )   S - 115   2023.10

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  • 新潟大学医歯学総合病院における糖代謝異常合併妊娠に関する周産期レジストリーの構築

    柳生田 紀子, 山田 貴穂, 西島 浩二, 有森 直子, 小川 洋平, 吉原 弘祐, 曽根 博仁

    糖尿病と妊娠   23 ( 3 )   S - 115   2023.10

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  • 血糖コントロールと妊娠合併症リスクとの量反応関係メタ回帰分析

    児玉 暁, 山田 貴穂, 柳生田 紀子, 谷内 洋子, 堀川 千嘉, 大澤 妙子, 北澤 勝, 藤原 和哉, 西島 浩二, 曽根 博仁

    糖尿病と妊娠   23 ( 3 )   S - 109   2023.10

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  • 帝王切開瘢痕部妊娠に対して腹式単純子宮全摘術を施行した1例

    和田 桃奈, 吉原 弘祐, 明石 絵里菜, 鈴木 美保, 安達 聡介, 西野 幸治, 関根 正幸, 生野 寿史, 西島 浩二

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   69回   93 - 93   2022.10

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  • Management of Condyloma Acuminata in Pregnancy: A Review

    Shunya Sugai, Koji Nishijima, Takayuki Enomoto

    Sexually Transmitted Diseases   48 ( 6 )   403 - 409   2021.6

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    DOI: 10.1097/OLQ.0000000000001322

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  • 新潟県における周産期メンタルヘルス研究の取り組み

    茂木 崇治, 福井 直樹, 藤田 真貴, 須貝 拓朗, 江川 純, 橋尻 洸陽, 坪谷 隆介, 三留 節子, 荒木 理恵, 生野 寿史, 山口 雅幸, 西島 浩二, 高桑 好一, 榎本 隆之, 染矢 俊幸

    新潟県医師会報   ( 838 )   7 - 8   2020.1

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  • Development of a novel therapy using dedifferentiated fat cells for necrotizing enterocolitis in neonates

    NISHIJIMA Koji

    Pediatric Academic Societies 2019 Meeting   2019.4

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  • 新生児壊死性腸炎における幹細胞療法の開発

    見松 はるか, 佐藤 義朗, 上田 一仁, 三浦 良介, 呉 尚治, 北瀬 悠磨, 鈴木 俊彦, 西島 浩二, 早川 昌弘

    日本新生児成育医学会雑誌   30 ( 3 )   770 - 770   2018.10

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  • 妊娠高血圧症候群と周辺疾患を考える 妊娠高血圧症候群に関連した中枢神経障害

    西島 浩二

    母性衛生   59 ( 3 )   68 - 68   2018.9

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  • 子宮底部横切開法後に妊娠成立し、計画的な周産期管理を行った一例

    田中 良明, 玉村 千代, 西島 浩二, 新谷 万智子, 山田 しず佳, 川村 裕士, 大沼 利通, 倉田 和巳, 津吉 秀昭, 高橋 仁, 吉田 好雄

    日本周産期・新生児医学会雑誌   54 ( 2 )   741 - 741   2018.6

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  • 腹腔鏡下筋腫核出術後に妊娠し、子宮破裂をきたした一例

    新谷 万智子, 大沼 利通, 山田 しず佳, 白藤 文, 川村 裕士, 玉村 千代, 倉田 和巳, 津吉 秀昭, 高橋 仁, 西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   54 ( 2 )   602 - 602   2018.6

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  • 腹腔鏡下筋腫核出術後に妊娠し、子宮破裂をきたした一例

    新谷 万智子, 大沼 利通, 山田 しず佳, 白藤 文, 川村 裕士, 玉村 千代, 倉田 和巳, 津吉 秀昭, 高橋 仁, 西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   54 ( 2 )   602 - 602   2018.6

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  • 常位胎盤早期剥離および前置胎盤剥離出血の発症形式についての検討 凝固・線溶マーカーはどのように動くか

    里見 裕之, 熊谷 亜矢子, 三屋 和子, 川村 裕士, 高橋 仁, 西島 浩二

    日本周産期・新生児医学会雑誌   54 ( 2 )   560 - 560   2018.6

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  • 子宮底部横切開法後に妊娠成立し、計画的な周産期管理を行った一例

    田中 良明, 玉村 千代, 西島 浩二, 新谷 万智子, 山田 しず佳, 川村 裕士, 大沼 利通, 倉田 和巳, 津吉 秀昭, 高橋 仁, 吉田 好雄

    日本周産期・新生児医学会雑誌   54 ( 2 )   741 - 741   2018.6

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  • 子宮底部横切開法後に妊娠成立し、計画的な周産期管理を行った一例

    田中 良明, 西島 浩二, 玉村 千代, 八代 憲司, 新谷 万智子, 西村 俊哉, 冨士井 杏子, 山本 輝, 宮崎 有美子, 山田 しず佳, 白藤 文, 川村 裕士, 大沼 利通, 倉田 和巳, 津吉 秀昭, 品川 明子, 高橋 仁, 知野 陽子, 折坂 誠, 黒川 哲司, 吉田 好雄, 服部 克成, 田嶋 公久

    福井県産婦人科医会学術集会抄録集   ( 9 )   18 - 18   2018.3

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  • 肝膿瘍と鑑別を要し、肝生検により診断された子宮頸癌の肝転移の1例

    高橋 望, 山田 しず佳, 白藤 文, 川村 裕士, 大沼 利通, 品川 明子, 高橋 仁, 知野 陽子, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    北海道産科婦人科学会会誌   62 ( 1 )   173 - 173   2018.3

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  • 肝膿瘍により血球貪食症候群を引き起こし、救命できなかった初産婦

    清水 可奈子, 坂野 陽通, 河原 和美, 飯藤 弘光, 伊藤 太郎, 冨士井 杏子, 山田 しず佳, 高橋 望, 高橋 仁, 西島 浩二, 折坂 誠, 吉田 好雄

    北海道産科婦人科学会会誌   62 ( 1 )   220 - 220   2018.3

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  • 広汎子宮頸部摘出術後に妊娠が成立した一例

    八代 憲司, 新谷 万智子, 田中 良明, 西村 俊哉, 冨士井 杏子, 山本 輝, 宮崎 有美子, 山田 しず佳, 白藤 文, 川村 裕士, 山本 真, 玉村 千代, 大沼 利通, 倉田 和巳, 津吉 秀昭, 品川 明子, 高橋 仁, 知野 陽子, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    福井県産婦人科医会学術集会抄録集   ( 9 )   11 - 11   2018.3

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  • 待機的に治療できた常位胎盤早期剥離3例の比較検討

    飯藤 弘光, 清水 可奈子, 岡 秀明, 鈴木 秀文, 山本 宝, 井上 大輔, 冨士井 杏子, 川村 裕士, 高橋 仁, 西島 浩二, 吉田 好雄

    福井県産婦人科医会学術集会抄録集   ( 9 )   7 - 7   2018.3

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  • 妊娠関連性乳癌(PABC;pregnancy associated breast cancer)早期発見を目指して 妊娠関連性乳癌16例の検討および,自施設での妊娠期乳房超音波検査結果の報告

    加藤 栄一, 黒川 哲司, 折坂 誠, 西島 浩二, 知野 陽子, 品川 明子, 高橋 仁, 津吉 秀昭, 倉田 和巳, 大沼 利通, 塚尾 麻由, 吉田 好雄

    日本産科婦人科学会雑誌   70 ( 2 )   775 - 775   2018.2

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  • 妊娠関連性乳癌(PABC;pregnancy associated breast cancer)早期発見を目指して 妊娠関連性乳癌16例の検討および,自施設での妊娠期乳房超音波検査結果の報告

    加藤 栄一, 黒川 哲司, 折坂 誠, 西島 浩二, 知野 陽子, 品川 明子, 高橋 仁, 津吉 秀昭, 倉田 和巳, 大沼 利通, 塚尾 麻由, 吉田 好雄

    日本産科婦人科学会雑誌   70 ( 2 )   775 - 775   2018.2

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  • 常位胎盤早期剥離の発症形式解明に関する検討 凝血学的診断によるアプローチ

    里見 裕之, 折坂 誠, 西島 浩二, 熊谷 亜矢子, 三屋 和子, 河野 久美子, 福野 直孝, 細川 久美子, 金嶋 光夫, 紙谷 尚之, 吉田 好雄

    日本産科婦人科学会雑誌   70 ( 2 )   975 - 975   2018.2

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  • 妊娠第2三半期における無症候性子宮頸管長短縮の出現時期と妊娠予後の検討

    川村 裕士, 西島 浩二, 玉村 千代, 高橋 仁, 折坂 誠, 吉田 好雄

    日本産科婦人科学会雑誌   70 ( 2 )   694 - 694   2018.2

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  • 腹腔鏡下筋腫核出術後に妊娠し,子宮破裂をきたした一例

    新谷 万智子, 大沼 利通, 田中 良明, 八代 憲司, 西村 俊哉, 宮崎 有美子, 川村 裕士, 玉村 千代, 高橋 仁, 西島 浩二, 黒川 哲司, 吉田 好雄

    日本産科婦人科学会雑誌   70 ( 2 )   876 - 876   2018.2

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  • トラブルを未然に防ぐための帝王切開術の工夫

    西島 浩二

    滋賀県産科婦人科雑誌   9   103 - 123   2017.12

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  • オウム病による国内初の妊産婦死亡例

    清水 可奈子, 吉村 芳修, 坂野 陽通, 川村 裕士, 高橋 仁, 西島 浩二, 折坂 誠, 河原 和美, 柳原 格, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   65回   118 - 118   2017.9

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  • 肺サーファクタントと胎脂は早産児の腸管を保護する 胎児期における肺-皮膚-消化器間相互作用の解明を目指して

    西島 浩二, 吉田 好雄

    日本肺サーファクタント・界面医学会雑誌   48   23 - 25   2017.9

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  • 今後の臨床応用が期待される基礎的研究 早産児の消化管保護に向けた治療戦略 肺サーファクタントと胎脂を用いた動物実験

    西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   53 ( 2 )   474 - 474   2017.6

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  • 超音波凝固切開装置を用いた子宮頸部円錐切除術既往妊娠の予後

    川村 裕士, 西島 浩二, 高橋 仁, 天谷 優介, 松山 純, 河原 和美, 干場 勉, 吉田 好雄

    日本周産期・新生児医学会雑誌   53 ( 2 )   653 - 653   2017.6

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  • 待機的管理を行った常位胎盤早期剥離の一例

    飯藤 弘光, 高橋 仁, 冨士井 杏子, 清水 可奈子, 伊藤 太郎, 山田 しず佳, 白藤 文, 川村 裕士, 玉村 千代, 大沼 利通, 倉田 和巳, 津吉 秀昭, 品川 明子, 知野 陽子, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    福井県産婦人科医会学術集会抄録集   ( 8 )   19 - 19   2017.3

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  • 子宮内膜異型増殖症および子宮体癌におけるホルモン療法反応性予測バイオマーカーとしての18F-FDG-PETおよび18F-FES PETの集積の意義

    山田 しず佳, 飯藤 弘光, 伊藤 太郎, 冨士井 杏子, 清水 可奈子, 高橋 望, 白藤 文, 川村 裕士, 山本 真, 玉村 千代, 大沼 利通, 倉田 和巳, 品川 明子, 高橋 仁, 知野 陽子, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    福井県産婦人科医会学術集会抄録集   ( 8 )   7 - 7   2017.3

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  • 若年浸潤性子宮頸がん術後に偶然発見された子宮体癌の一例

    伊藤 太郎, 飯藤 弘光, 冨士井 杏子, 清水 可奈子, 山田 しず佳, 白藤 文, 川村 裕士, 玉村 千代, 大沼 利通, 倉田 和己, 津吉 秀昭, 品川 明子, 高橋 仁, 知野 陽子, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    福井県産婦人科医会学術集会抄録集   ( 8 )   25 - 25   2017.3

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  • 常位胎盤早期剥離診断スコアの有用性の検討

    里見 裕之, 折坂 誠, 西島 浩二, 高多 佑佳, 熊谷 亜矢子, 三屋 和子, 河野 久美子, 福野 直孝, 細川 久美子, 金嶋 光夫, 紙谷 尚之, 吉田 好雄

    日本産科婦人科学会雑誌   69 ( 2 )   757 - 757   2017.2

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  • 羊水過多を呈した妊婦に対し、問診を契機に筋強直性ジストロフィーと診断した3症例

    飯藤 弘光, 清水 可奈子, 伊藤 太郎, 冨士井 杏子, 坂野 陽通, 佐藤 久美子, 玉村 千代, 高橋 仁, 西島 浩二, 吉田 好雄

    日本産科婦人科学会雑誌   69 ( 2 )   888 - 888   2017.2

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  • 妊娠中に肝膿瘍による血球貪食症候群を引き起こし、救命できなかった一例

    清水 可奈子, 飯藤 弘光, 伊藤 太郎, 冨士井 杏子, 坂野 陽通, 川村 裕士, 玉村 千代, 高橋 仁, 西島 浩二, 折坂 誠, 河原 和美, 吉田 好雄

    日本産科婦人科学会雑誌   69 ( 2 )   877 - 877   2017.2

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  • 分娩監視装置の超音波ドプラ信号による心拍細変動解析精度の定量的な評価

    玉村 千代, 荒木 睦大, 森 幹男, 浅井 竜哉, 高橋 望, 西島 浩二, 吉田 好雄

    電子情報通信学会技術研究報告(超音波)   116 ( 419 )   227 - 232   2017.1

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  • 肝膿瘍により血球貪食症候群を引き起こし、救命できなかった初産婦

    清水 可奈子, 坂野 陽通, 河原 和美, 飯塚 弘光, 伊藤 太郎, 冨士井 杏子, 山田 しず佳, 高橋 望, 高橋 仁, 西島 浩二, 折坂 誠, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   64回   146 - 146   2016.9

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  • 肝膿瘍と鑑別を要し、肝生検により診断された子宮頸癌の肝転移の1例

    高橋 望, 山田 しず佳, 白藤 文, 川村 裕士, 大沼 利通, 品川 明子, 高橋 仁, 知野 陽子, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   64回   91 - 91   2016.9

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  • The Methods to Denoize the Fetal Heart Doppler Sound Obtained by Ultrasound Cardiograph Using Wavelet Analysis

    46 ( 6 )   373 - 378   2016.8

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  • The Methods to Denoize the Fetal Heart Doppler Sound Obtained by Ultrasound Cardiograph Using Wavelet Analysis

    116 ( 179 )   31 - 36   2016.8

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  • The Methods to Denoize the Fetal Heart Doppler Sound Obtained by Ultrasound Cardiograph Using Wavelet Analysis

    46 ( 5 )   321 - 326   2016.7

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  • 福井大学における前置胎盤の管理実績

    天谷 優介, 高橋 望, 山本 真, 倉田 和巳, 高橋 仁, 西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   52 ( 2 )   738 - 738   2016.6

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  • 演者らの開発した腹膜外帝王切開法 手技と子宮内感染症例での有用性

    中後 聡, 小寺 知揮, 柴田 貴司, 加藤 大樹, 大石 哲也, 小辻 文和, 黒川 哲司, 西島 浩二

    産婦人科手術   ( 27 )   154 - 154   2016.6

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  • 前置胎盤での帝王切開の対応と工夫 子宮底部横切開法の工夫

    西島 浩二

    日本周産期・新生児医学会雑誌   52 ( 2 )   480 - 480   2016.6

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  • 壊死性腸炎の発症予防 肺サーファクタントと胎脂を用いた消化管保護に向けての治療戦略

    西島 浩二

    日本周産期・新生児医学会雑誌   52 ( 2 )   474 - 474   2016.6

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  • 胎児心音を用いた瞬時胎児心拍変動解析の実験システム

    荒木 睦大, 森 幹男, 浅井 竜哉, 高橋 望, 知野 陽子, 西島 浩二, 吉田 好雄

    電子情報通信学会技術研究報告(超音波)   116 ( 84 )   5 - 10   2016.6

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  • 帝王切開術後骨盤内膿瘍の予防に向けた当院の治療戦略

    佐藤 久美子, 山本 真, 高橋 仁, 西島 浩二, 田嶋 公久, 吉田 好雄

    日本周産期・新生児医学会雑誌   52 ( 2 )   779 - 779   2016.6

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  • Toward to Develop an Monitoring System of Fetal Heart Rate Variability Using Fetal Heart Sound

    46 ( 3 )   147 - 152   2016.5

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  • 帝王切開における子宮創部癒合不全の防止法及びその治療法 帝王切開における子宮創部癒合不全の防止法

    西島 浩二, 吉田 好雄, 小辻 文和

    日本女性医学学会雑誌   23 ( 2 )   365 - 365   2016.4

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  • 子宮内感染例の帝切後の創離開への対策 創修復・子宮摘出・1年後の修復 10症例の経験から

    加藤 大樹, 柴田 貴司, 徳田 妃里, 松木 理薫子, 小寺 知揮, 中後 聡, 大石 哲也, 小辻 文和, 西島 浩二, 吉田 好雄

    日本産科婦人科学会雑誌   68 ( 2 )   981 - 981   2016.2

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  • 救命しえなかった肺高血圧症合併妊娠の1例

    高橋 望, 天谷 優介, 冨士井 杏子, 杉田 元気, 高橋 仁, 品川 明子, 福田 真, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    日本産科婦人科学会雑誌   68 ( 2 )   751 - 751   2016.2

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  • 早産管理と児の予後 肺サーファクタントと胎脂は早産児の腸管を保護する 胎児期における肺-皮膚-消化器間相互作用の解明を目指して

    西島 浩二, 高橋 仁, 吉田 好雄

    日本産科婦人科学会雑誌   68 ( 2 )   595 - 595   2016.2

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  • 神経線維腫症I型(レックリングハウゼン病)合併妊娠の3症例の報告

    天谷 優介, 高橋 仁, 西島 浩二, 井上 大輔, 高橋 望, 山本 真, 折坂 誠, 黒川 哲司, 吉田 好雄

    日本産科婦人科学会雑誌   68 ( 2 )   947 - 947   2016.2

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  • 治療抵抗性重症特発性血小板減少性紫斑病(ITP)合併妊娠の管理

    玉村 千代, 吉田 好雄, 折坂 誠, 黒川 哲司, 西島 浩二, 福田 真, 高橋 仁, 井上 大輔

    日本産科婦人科学会雑誌   68 ( 2 )   757 - 757   2016.2

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  • 術中から始まる周術期感染対策 帝王切開術後骨盤内膿瘍の予防に向けた当院の治療戦略

    佐藤 久美子, 西島 浩二, 吉田 好雄

    日本外科感染症学会雑誌   12 ( 5 )   483 - 483   2015.11

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  • 帝王切開における子宮創部癒合不全の防止法及びその治療法 帝王切開における子宮創部癒合不全の防止法

    西島 浩二, 吉田 好雄, 小辻 文和

    日本女性医学学会雑誌   23 ( Suppl. )   110 - 110   2015.10

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  • 神経線維腫症I型(レックリングハウゼン病)合併妊娠の3症例の報告

    天谷 優介, 高橋 仁, 西島 浩二, 井上 大輔, 高橋 望, 山本 真, 折坂 誠, 黒川 哲司, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   63回   104 - 104   2015.9

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  • 妊娠中に急性白血病と診断された3症例の報告

    井上 大輔, 高橋 仁, 西島 浩二, 太田 可奈子, 山本 真, 吉田 好雄

    日本周産期・新生児医学会雑誌   51 ( 2 )   890 - 890   2015.6

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  • 妊娠19週にARB内服を中止したが無羊水症が遷延した一例

    太田 可奈子, 玉村 千代, 井上 大輔, 山本 真, 高橋 仁, 西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   51 ( 2 )   808 - 808   2015.6

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  • Marginal insertion with Velamentous vesselの臨床像

    高橋 仁, 高橋 望, 山本 真, 西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   51 ( 2 )   675 - 675   2015.6

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  • 超緊急帝王切開術における麻酔法の検討

    佐藤 久美子, 山本 真, 大沼 利通, 西島 浩二, 田嶋 公久, 吉田 好雄

    日本周産期・新生児医学会雑誌   51 ( 2 )   939 - 939   2015.6

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  • 交通事故後に子宮内胎児死亡に至った一例

    山田 しず佳, 高橋 仁, 西島 浩二, 品川 明子, 黒川 哲司, 折坂 誠, 吉田 好雄

    北海道産科婦人科学会会誌   59 ( 1 )   205 - 206   2015.3

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  • 神経線維腫症に合併した褐色細胞腫による高血圧クリーゼを契機に発症した心肺虚脱型羊水塞栓症の一例

    高橋 望, 白藤 文, 加藤 加奈, 津吉 秀昭, 西島 浩二, 黒川 哲司, 折坂 誠, 吉田 好雄

    北海道産科婦人科学会会誌   59 ( 1 )   197 - 198   2015.3

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  • 娩出時期の設定に苦慮した品胎症例

    山本 真, 折坂 誠, 森下 史子, 服部 克成, 打波 郁子, 西島 浩二, 黒川 哲司, 吉田 好雄

    北海道産科婦人科学会会誌   59 ( 1 )   173 - 174   2015.3

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  • 当院におけるTOLAC症例の検討

    杉田 元気, 加藤 加奈, 河原 和美, 福田 真, 西島 浩二, 吉田 好雄

    北海道産科婦人科学会会誌   59 ( 1 )   202 - 203   2015.3

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  • Authors' reply

    K. Nishijima, J. Takahashi, M. Orisaka, T. Kurokawa, C. Tamamura, A. Yoshida, H. Masuzaki, T. Sekiya, Y. Yoshida, F. Kotsuji

    BJOG: An International Journal of Obstetrics and Gynaecology   122 ( 3 )   448 - 449   2015.2

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    DOI: 10.1111/1471-0528.13259

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  • Transverse uterine fundal incision for placenta praevia with accreta: concern regarding its 'overuse' Reply

    K. Nishijima, J. Takahashi, M. Orisaka, T. Kurokawa, C. Tamamura, A. Yoshida, H. Masuzaki, T. Sekiya, Y. Yoshida, F. Kotsuji

    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY   122 ( 3 )   448 - 449   2015.2

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    DOI: 10.1111/1471-0528.13259

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  • 胎盤ポリープに対する新しい画像評価の試み 造影剤を使用しない非侵性の灌流MRIは胎盤ポリープの血流評価に有用か

    太田 可奈子, 黒川 哲司, 高橋 仁, 西島 浩二, 折坂 誠, 吉田 好雄, 金本 雅之, 藤原 康博, 木村 浩彦, 山元 龍哉, 小坂 信之, 松田 豪

    日本産科婦人科学会雑誌   67 ( 2 )   635 - 635   2015.2

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  • 感染を背景に有する早産症例に対し、帝王切開術後創部感染を防ぐための当院の試み

    佐藤 久美子, 玉村 千代, 高橋 仁, 西島 浩二, 田嶋 公久, 吉田 好雄

    日本産科婦人科学会雑誌   67 ( 2 )   970 - 970   2015.2

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  • 急性白血病合併妊娠3症例の報告

    井上 大輔, 高橋 仁, 西島 浩二, 山本 真, 福田 真, 折坂 誠, 黒川 哲司, 吉田 好雄

    日本産科婦人科学会雑誌   67 ( 2 )   938 - 938   2015.2

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  • 超低出生体重児の消化管機能の成熟に向けた治療戦略 肺サーファクタントと胎脂を用いた動物実験

    西島 浩二, 吉田 好雄

    日本肺サーファクタント・界面医学会雑誌   45   16 - 27   2014.10

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  • 妊娠19週にARB内服を中止したが無羊水症が遷延し、中期中絶が選択された一例

    太田 可奈子, 玉村 千代, 井上 大輔, 高橋 仁, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   62回   94 - 94   2014.9

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  • 妊娠後期における筋緊張性ジストロフィー合併妊娠の胎児超音波診断

    高橋 仁, 西島 浩二, 井上 大輔, 太田 加奈子, 杉田 元気, 山本 真, 玉村 千代, 品川 明子, 知野 陽子, 福田 真, 折坂 誠, 黒川 哲司, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   62回   62 - 62   2014.9

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  • An Experimental System to Measure RR Interval of Fetal Heart Using Heart Sound

    44 ( 5 )   267 - 270   2014.6

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  • An Experimental System to Measure RR Interval of Fetal Heart Using Heart Sound

    Mori Mikio, Nishijima Koji, Asai Tatsuya, Ogoshi Yasuhiro, Shirai Haruhiko, Taniguchi Syuji, Araki Chikahiro

    IEICE technical report. Welfare Information technology   114 ( 92 )   23 - 26   2014.6

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    It is pointed out that the importance of fetal-heart-rate baseline variability on fetal-heart-rate monitoring used for diagnosis of embryonic health condition. However, the instantaneous RR Time Interval is hardly obtained on conventional method using ultrasonic Doppler reflected signal. In this paper, an experimental system to measure RR interval of fetal heart using heart sound is proposed.

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  • 帝王切開後に子宮筋層切開部感染を生じた4症例

    佐藤 久美子, 山本 真, 高橋 仁, 西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   50 ( 2 )   921 - 921   2014.6

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  • 超低出生体重児の消化管機能成熟に向けた治療戦略 胎児肺-皮膚-消化管間相互作用の解明を目指して

    西島 浩二, 高橋 仁, 山本 真, 佐藤 久美子, 吉田 好雄

    日本周産期・新生児医学会雑誌   50 ( 2 )   872 - 872   2014.6

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  • 先天性筋緊張性ジストロフィーが推測される胎児の超音波診断

    高橋 仁, 山本 真, 佐藤 久美子, 西島 浩二, 吉田 好雄

    日本周産期・新生児医学会雑誌   50 ( 2 )   704 - 704   2014.6

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  • Placenta praevia accreta Reply

    K. Nishijima, Y. Yoshida, F. Kotsuji

    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY   121 ( 6 )   773 - 775   2014.5

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    DOI: 10.1111/1471-0528.12555

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  • Maternal and perinatal consequences of antepartum haemorrhage of unknown origin (vol 121, pg 44, 2014)

    K. Nishijima, Y. Yoshida, F. Kotsuji

    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY   121 ( 6 )   771 - 772   2014.5

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    DOI: 10.1111/1471-0528.12556

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  • Prenatal diagnosis of congenital myotonic dystrophy in the third trimester of pregnancy using ultrasonography

    NISHIJIMA Koji

    25th Annual Meeting of Asia-Pacific Endocrine Conference(APEC)   2014.3

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  • 超低出生体重児の消化管機能成熟に向けた治療戦略 胎児肺-皮膚-消化管間相互作用の解明を目指して

    西島 浩二, 高橋 仁, 折坂 誠, 黒川 哲司, 吉田 好雄

    日本産科婦人科学会雑誌   66 ( 2 )   720 - 720   2014.2

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  • 神経線維腫症に合併した褐色細胞腫による高血圧クリーゼを契機に発症した心肺虚脱型羊水塞栓症の1例

    高橋 望, 津吉 秀昭, 西島 浩二, 黒川 哲司, 折坂 誠, 吉田 好雄

    日本産科婦人科学会雑誌   66 ( 2 )   769 - 769   2014.2

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  • 正常血圧でreversible posterior leukoencephalopathy syndromeを発症し産褥子癇と最終診断した一例

    山本 真, 服部 克成, 福田 真, 西島 浩二, 折坂 誠, 吉田 好雄

    日本産科婦人科学会雑誌   66 ( 2 )   761 - 761   2014.2

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  • 重症妊娠高血圧腎症における新たな降圧指針作成の可能性 胎児臍帯動脈血流速度波形からのアプローチ

    上林 大岳, 西島 浩二, 打波 郁子, 山本 真, 佐藤 久美子, 高橋 仁, 折坂 誠, 黒川 哲司, 吉田 好雄

    福井大学医学部研究雑誌   14 ( 1 )   1 - 4   2014.1

  • Authors' reply: transverse uterine fundal incision for placenta praevia with accreta

    K.Nishijima, Y.Yoshida, F.Kotsuji

    BJOG   121 ( 6 )   771 - 2   2014

  • Authors' reply: Transverse uterine fundal incision in placenta praevia with possible placenta accreta

    K. Nishijima, Y. Yoshida, F. Kotsuji

    BJOG: An International Journal of Obstetrics and Gynaecology   121 ( 6 )   771 - 772   2014

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    DOI: 10.1111/1471-0528.12556

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  • 超低出生体重児の消化管成熟に向けた治療戦略 肺サーファクタントと胎脂を用いた動物実験

    西島 浩二, 吉田 好雄

    日本肺サーファクタント・界面医学会雑誌   44   20 - 22   2013.11

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  • 当院におけるTOLAC症例の検討

    杉田 元気, 加藤 加奈, 河原 和美, 福田 真, 西島 浩二, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   61回   96 - 96   2013.9

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  • 神経線維腫症に合併した褐色細胞腫による高血圧クリーゼを契機に発症した心肺虚脱型羊水塞栓症の1例

    高橋 望, 白藤 文, 加藤 加奈, 津吉 秀昭, 西島 浩二, 黒川 哲司, 折坂 誠, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   61回   90 - 90   2013.9

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  • 娩出時期の設定に苦慮した品胎症例

    山本 真, 折坂 誠, 森下 史子, 服部 克成, 打波 郁子, 西島 浩二, 黒川 哲司, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   61回   62 - 62   2013.9

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  • 交通事故後に子宮内胎児死亡に至った一例

    山田 しず佳, 高橋 仁, 西島 浩二, 品川 明子, 黒川 哲司, 折坂 誠, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   61回   99 - 99   2013.9

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  • 神経線維腫症に合併した褐色細胞腫クリーゼを契機に発症した心肺虚脱型羊水塞栓症の1例

    高橋 望, 西島 浩二, 打波 郁子, 津吉 秀昭, 吉田 好雄

    日本周産期・新生児医学会雑誌   49 ( 2 )   741 - 741   2013.6

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  • A retrospective review of velamentous cord insertion

    NISHIJIMA Koji

    XI World congress of perinatal medicine(WCPM)   2013.6

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  • A novel treatment strategy for the gastrointestinal development of extremely premature infants: administration of micelles derived from pulmonary surfactants and the vernix caseosa in pregnant rabbits

    NISHIJIMA Koji

    XI World congress of perinatal medicine (WCPM)   2013.6

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  • 既往帝王切開術後妊娠におけるVBAC例の検討

    加藤 加奈, 杉田 元気, 福田 真, 河原 和美, 西島 浩二, 吉田 好雄

    日本産科婦人科学会雑誌   65 ( 2 )   822 - 822   2013.2

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  • 当院における子宮内膜細胞診に液状検体法を導入した子宮体癌のスクリーニング法の現状

    黒川 哲司, 品川 明子, 知野 陽子, 津吉 秀昭, 西島 浩二, 折坂 誠, 吉田 好雄

    日本産科婦人科学会雑誌   65 ( 2 )   590 - 590   2013.2

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  • P2-43-10 既往帝王切開術後妊娠におけるVBAC例の検討(Group 95 分娩手技2,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

    加藤 加奈, 杉田 元気, 福田 真, 河原 和美, 西島 浩二, 吉田 好雄

    日本産科婦人科學會雜誌   65 ( 2 )   822 - 822   2013

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  • 妊娠子宮嵌頓症における診断のポイントと帝王切開の留意点

    服部 克成, 高橋 望, 加藤 加奈, 北野 史子, 玉村 千代, 打波 郁子, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   60回   87 - 87   2012.9

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  • 臍帯卵膜付着の後方視的検討

    高橋 仁, 服部 由香, 吉田 好雄, 黒川 哲司, 折坂 誠, 西島 浩二, 打波 郁子, 服部 克成, 品川 明子, 津吉 秀昭, 杉田 元気, 白藤 文

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   60回   91 - 91   2012.9

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  • 食道癌合併妊娠の1例

    高橋 望, 折坂 誠, 服部 克成, 加藤 加奈, 北野 史子, 津吉 秀昭, 品川 明子, 知野 陽子, 打波 郁子, 西島 浩二, 黒川 哲司, 吉田 好雄

    北日本産科婦人科学会総会・学術講演会プログラム・抄録集   60回   127 - 127   2012.9

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  • 当院における臍帯付着部異常症例の検討

    高橋 仁, 服部 由香, 小辻 文和, 西島 浩二, 打波 郁子, 津吉 秀昭

    日本周産期・新生児医学会雑誌   48 ( 2 )   540 - 540   2012.6

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  • 超低出生体重児の消化管成熟に向けた治療戦略 肺サーファクタントと胎脂を用いた動物実験

    西島 浩二, 高橋 仁, 打波 郁子, 黒川 哲司, 折坂 誠, 小辻 文和

    日本産科婦人科学会雑誌   64 ( 2 )   405 - 405   2012.2

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  • 超低出生体重児の消化管成熟に向けた治療戦略 肺サーファクタントと胎脂を用いた動物実験

    西島 浩二, 高橋 仁, 打波 郁子, 小辻 文和

    日本周産期・新生児医学会雑誌   47 ( 2 )   396 - 396   2011.6

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  • FES-PETを用いた筋腫内ER評価の有用性 妊娠中の筋腫サイズ変化の予測のために

    服部 克成, 西島 浩二, 高橋 仁, 折坂 誠, 黒川 哲司, 吉田 好雄, 小辻 文和

    北海道産科婦人科学会会誌   55 ( 1 )   149 - 150   2011.3

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  • 痩せと妊娠 巨大な胎盤低エコー像とIUGRを呈した症例

    高橋 仁, 折坂 誠, 西島 浩二, 小辻 文和

    北海道産科婦人科学会会誌   55 ( 1 )   141 - 141   2011.3

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  • 18週未満に発症した破水症例の妊娠転帰とCervical sealingの是非

    折坂 誠, 西島 浩二, 服部 克成, 高橋 仁, 小辻 文和

    北海道産科婦人科学会会誌   55 ( 1 )   140 - 140   2011.3

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  • 50症例の経験から「子宮底部横切開による帝切法」の有用性と問題点を考える 前置癒着胎盤に対する安全な手術法の確立を目指して

    西島 浩二, 小辻 文和, 水上 尚典, 斎藤 豪, 遠藤 俊明, 宇田川 康博, 関谷 隆夫, 阪西 通夫

    日本産科婦人科学会雑誌   63 ( 2 )   573 - 573   2011.2

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  • 重症妊娠高血圧腎症における新たな降圧指針作成の可能性 臍帯動脈血流速度波形からのアプローチ

    上林 大岳, 西島 浩二, 打波 郁子, 佐藤 久美子, 服部 克成, 黒川 哲司, 折坂 誠, 小辻 文和

    日本産科婦人科学会雑誌   63 ( 2 )   643 - 643   2011.2

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  • 膀胱浸潤を伴った前置癒着胎盤の1例

    岡田 昌裕, 青木 芳隆, 関 雅也, 稲村 聡, 大山 伸幸, 三輪 吉司, 秋野 裕信, 横山 修, 西島 浩二, 黒川 哲司, 吉田 好雄, 小辻 文和, 太田 諒, 今村 好章

    泌尿器科紀要   56 ( 6 )   341 - 341   2010.6

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  • 2009 H1N1インフルエンザの感染により急速に進行した早産症例の検討

    西島 浩二, 打波 郁子, 高橋 仁, 小辻 文和

    日本周産期・新生児医学会雑誌   46 ( 2 )   455 - 455   2010.6

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  • On Being a Resident and a Mom

    Koji Nishijima, Jin Takahashi, Makoto Yamamoto, Makoto Orisaka, Chiyo Suzuki, Hirokazu Tsukahara, Ken-ichi Shukunami, Tetsuji Kurokawa, Yoshio Yoshida, Fumikazu Kotsuji

    ANNALS OF EMERGENCY MEDICINE   55 ( 5 )   483 - +   2010.5

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  • Usefulness of the transverse uterine fundal incision for placenta previa

    NISHIJIMA Koji

    The XXⅡ European Congress of perinatal Medicine   2010.5

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  • 安全で容易な腹膜外帝切法とトレーニング法の開発 反復帝切による腹腔内癒着回避の対策

    黒川 哲司, 西島 浩二, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   62 ( 2 )   464 - 464   2010.2

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  • 妊娠18週未満の前期破水に対する治療戦略 Cervical sealing(子宮頸部シール法)の開発

    折坂 誠, 西島 浩二, 服部 克成, 高橋 仁, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   62 ( 2 )   644 - 644   2010.2

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  • 広範囲な穿通胎盤症例の膀胱温存法 病的膀胱の修復とカテーテル留置による膀胱摘出の回避

    西島 浩二, 黒川 哲司, 高橋 仁, 山本 真, 折坂 誠, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   62 ( 2 )   606 - 606   2010.2

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  • Delayed interval deliveryにおける第1子胎盤の娩出タイミング

    北野 史子, 折坂 誠, 高橋 仁, 品川 明子, 打波 郁子, 西島 浩二, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   62 ( 2 )   603 - 603   2010.2

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  • 先天代謝異常症における一酸化窒素代謝系の病態学的意義の探索: 新規の予防・治療法の開発に向けて

    塚原 宏一, 徳力 周子, 田村 知史, 川谷 正男, 畑 郁江, 大嶋 勇成, 西島 浩二

    福井大学重点研究成果集 (in press)   2010

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  • Ureaplasma urealyticum感染が病因と考えられ、呼吸管理に難渋したWilson-Mikity症候群の1例

    徳力 周子, 五十嵐 愛子, 菊地 尚子, 田村 知史, 畑 郁江, 塚原 宏一, 眞弓 光文, 高橋 仁, 西島 浩二, 小辻 文和, 長谷川 妙子, 小出 亜希子, 柳原 格, 佐々木 裕子, 見理 剛

    日本小児科学会雑誌   113 ( 12 )   1867 - 1867   2009.12

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  • 子宮頸部腺癌合併妊娠の1例

    澤村 陽子, 北野 史子, 品川 明子, 西島 浩二, 黒川 哲司, 吉田 好雄, 小辻 文和

    日本婦人科腫瘍学会雑誌   27 ( 3 )   303 - 303   2009.6

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  • アンドロゲン過剰症がその原因と推察された子宮頸管無力症の1例

    山本 真, 西島 浩二, 高橋 仁, 折坂 誠, 小辻 文和

    日本産科婦人科学会雑誌   61 ( 2 )   595 - 595   2009.2

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  • 妊娠初期の胎盤辺縁の形態に着目し、胎盤辺縁の角度を測定することによって、前置胎盤の発生を予測する

    西島 浩二, 宿南 憲一, 高橋 仁, 山本 真, 打波 郁子, 小辻 文和

    日本産科婦人科学会雑誌   61 ( 2 )   483 - 483   2009.2

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  • 妊娠経過中に著明な縮小を認めた子宮筋腫合併妊娠の1例

    服部 克成, 高橋 仁, 西島 浩二, 折坂 誠, 黒川 哲司, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   61 ( 2 )   605 - 605   2009.2

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  • 周産期におけるMycoplasma hominis, Ureaplasma urealyticum感染の早期スクリーニング法と超早産児の気管支肺異形成発症予防策の確立

    徳力 周子, 塚原 宏一, 西島 浩二

    トランスレーションリサーチ推進センター 2008年度活動報告書   7 - 8   2009

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  • 早産児の栄養 超低出生体重児の消化管成熟に向けた治療戦略 肺サーファクタントを用いた動物実験

    西島 浩二, 宿南 憲一, 高橋 仁, 塚原 宏一, 小辻 文和

    日本周産期・新生児医学会雑誌   44 ( 4 )   978 - 981   2008.12

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  • アンドロゲン過剰症が子宮頸管無力症の原因と考えられた一例

    福田 真, 山本 真, 西島 浩二, 折坂 誠, 小辻 文和

    日本内分泌学会雑誌   84 ( 3 )   858 - 858   2008.12

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  • L-arginine/NOS/NO系とPRMT/ADMA/DDAH系のバランスの臨床的重要性

    塚原 宏一, 巨田 尚子, 徳力 周子, 田村 知史, 豊岡 美千代, 西島 浩二, 折坂 誠, 小辻 文和, 太田 徳仁, 川上 寿子, 関根 恭一, 長坂 博範, 眞弓 光文

    発達腎研究会誌   16 ( 1 )   21 - 28   2008.7

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  • 早産児の栄養 超低出生体重児の消化管成熟に向けた治療戦略 肺サーファクタントを用いた動物実験

    西島 浩二, 高橋 仁, 小辻 文和

    日本周産期・新生児医学会雑誌   44 ( 2 )   299 - 299   2008.6

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  • 未成熟子宮妊娠

    高橋 仁, 西島 浩二, 小辻 文和

    日本周産期・新生児医学会雑誌   44 ( 2 )   365 - 365   2008.6

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  • 前置癒着胎盤及び広範な前壁付着を伴う前置胎盤に対する新たな帝王切開法 子宮底部横切開法の安全性と有用性

    西島 浩二, 宿南 憲一, 折坂 誠, 田嶋 公久, 塚原 宏一, 河合 泰一, 吉田 好雄, 小辻 文和

    日本産婦人科・新生児血液学会誌   17 ( 2 )   39 - 42   2008.3

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  • 超音波ドプラ法によるperinasal fluid flowの観察 胎児診断、特に出生後の呼吸機能予測への応用

    西島 浩二, 鈴木 千代, 佐藤 久美子, 高橋 仁, 打波 郁子, 折坂 誠, 小辻 文和

    日本産科婦人科学会雑誌   60 ( 2 )   746 - 746   2008.2

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  • 小型カボチャを利用した子宮鏡手術訓練モデル

    田嶋 公久, 鈴木 千代, 佐藤 久美子, 品川 明子, 澤村 陽子, 打波 郁子, 福田 真, 西島 浩二, 折坂 誠, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   60 ( 2 )   829 - 829   2008.2

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  • Influence of adnexal torsion on tubal functions in rabbits

    NISHIJIMA Koji

    Fourth Canada-Japan Bilateral Workshop on Human Reproduction & Reproductive Biology   2007.8

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  • エリスロポイエチン高値の生体応答学的意義について

    塚原 宏一, 小倉 一将, 古畑 律代, 田村 知史, 眞弓 光文, 西島 浩二, 宿南 憲一, 小辻 文和, 上野 正樹

    発達腎研究会誌   15 ( 1 )   25 - 33   2007.7

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  • 前置胎盤に対する対応 前置癒着胎盤及び広範な前壁付着を伴う前置胎盤に対する新たな帝切法 子宮底部横切開法の安全性と有用性

    西島 浩二, 折坂 誠, 田嶋 公久, 吉田 好雄, 小辻 文和

    日本産婦人科・新生児血液学会誌   17 ( 1 )   S - 11   2007.6

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  • 子宮鏡手術トレーニングの工夫 割り箸レゼクトスコープを用いたTCR訓練

    田嶋 公久, 佐藤 久美子, 鈴木 千代, 品川 明子, 澤村 陽子, 福田 真, 西島 浩二, 折坂 誠, 吉田 好雄, 小辻 文和

    日本産科婦人科内視鏡学会雑誌   22 ( 2 )   339 - 339   2007.3

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  • 前置癒着胎盤及び広範な前壁付着を伴う前置胎盤に対する新たな帝切法 子宮底部横切開法の安全性と有用性

    西島 浩二, 折坂 誠, 田嶋 公久, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   59 ( 2 )   503 - 503   2007.2

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  • 胎児期から青年期にかけてのAdvanced glycation end-products生成の評価 ヒトにおける"carbonyl stress"の評価

    塚原 宏一, 古畑 律代, 田村 知史, 羽田 敦子, 眞弓 光文, 西島 浩二, 宿南 憲一, 上野 正樹, 川上 寿子, 内山 真由美, 関根 恭一, 三浦 雅一

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  • 突然の子宮内胎児死亡に至った劇症1型糖尿病症例 尿中ケトン体陽性例の取り扱いについて

    高橋 仁, 西島 浩二, 八木原 亮, 宿南 憲一, 仙田 亨, 小辻 文和

    北海道産科婦人科学会会誌   50 ( 1 )   94 - 95   2006.6

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  • 高度肥満妊婦の帝王切開術

    有倉 清香, 宿南 憲一, 西島 浩二, 石田 善建, 打波 郁子, 小辻 文和

    北海道産科婦人科学会会誌   50 ( 1 )   70 - 70   2006.6

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  • 骨軟骨異形成症の超音波診断

    服部 克成, 西島 浩二, 宿南 憲一, 大月 澄, 竹内 譲, 小辻 文和

    北海道産科婦人科学会会誌   50 ( 1 )   100 - 100   2006.6

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  • Placenta previa "migration" in the third trimester of pregnancy

    K Shukunami, K Nishijima, Uchinami, I, K Tajirna, Y Yoshida, F Kotsuji

    JOURNAL OF ULTRASOUND IN MEDICINE   24 ( 11 )   1560 - 1560   2005.11

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  • 突然の子宮内胎児死亡に至った劇症1型糖尿病症例 尿中ケトン体陽性例の取り扱いについて

    高橋 仁, 西島 浩二, 八木原 亮, 宿南 憲一, 仙田 亨, 小辻 文和

    日本産科婦人科学会東北連合地方部会誌   ( 53 )   68 - 69   2005.11

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  • 高度肥満妊婦の帝王切開術

    有倉 清香, 宿南 憲一, 西島 浩二, 石田 善建, 打波 郁子, 小辻 文和

    日本産科婦人科学会東北連合地方部会誌   ( 53 )   49 - 50   2005.11

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  • 骨軟骨異形成症の超音波診断

    服部 克成, 西島 浩二, 宿南 憲一, 大月 澄, 竹内 譲, 小辻 文和

    日本産科婦人科学会東北連合地方部会誌   ( 53 )   73 - 73   2005.11

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  • Is sonographic cervical length meaningful for the prediction of successful induction of labor?

    K Shukunami, K Nishijima, Uchinami, I, K Tajima, Y Yoshida, F Kotsuji

    JOURNAL OF ULTRASOUND IN MEDICINE   24 ( 10 )   1461 - 1461   2005.10

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  • Accidental fetal lacerations during cesarean delivery: Experience in an Italian level III university hospital

    K Nishijima, K Shukunami, F Kotsuji

    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY   193 ( 3 )   897 - 898   2005.9

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    DOI: 10.1016/j.ajog.2005.02.124

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  • Responses by pregnant Jehovah's witnesses on health care proxies [3] (multiple letters)

    J. Mervyn Thomas, Ken-Ichi Shukunami, Koji Nishijima, Yoshio Yoshida, Fumikazu Kotsuji, Cynthia Gyamfi, Richard L. Berkowitz

    Obstetrics and Gynecology   105 ( 2 )   441 - 443   2005.2

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    DOI: 10.1097/01.AOG.0000149842.31312.e4

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  • Responses by pregnant Jehovah&apos;s witnesses on health care proxies

    K Shukunami, K Nishijima, Y Yoshida, F Kotsuji

    OBSTETRICS AND GYNECOLOGY   105 ( 2 )   442 - 442   2005.2

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    DOI: 10.1097/01.AOG.0000152005.80380.48

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  • 肺サーファクタントはウサギ胎仔小腸上皮を成熟させる 胎児肺-消化管間interaction解明への試み

    西島 浩二, 宿南 憲一, 打波 郁子, 吉成 秀夫, 小辻 文和

    日本産科婦人科学会雑誌   57 ( 2 )   705 - 705   2005.2

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    Other Link: https://projects.repo.nii.ac.jp/?action=repository_uri&item_id=436181

  • Kinematic MRIによる産褥子宮の機能的評価

    打波 郁子, 西島 浩二, 福田 真, 折坂 誠, 黒川 哲司, 有倉 清香, 宿南 憲一, 小辻 文和

    日本産科婦人科学会雑誌   57 ( 2 )   699 - 699   2005.2

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  • 妊娠初期の胎盤辺縁角測定による分娩期前置胎盤の予測

    宿南 憲一, 西島 浩二, 打波 郁子, 黒川 哲司, 小辻 文和

    日本産科婦人科学会雑誌   57 ( 2 )   536 - 536   2005.2

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  • Conservative versus extirpative management in cases of placenta accreta [4] (multiple letters)

    Olivia Fiori, Nadia Berkane, Serge Uzan, Gilles Kayem, Koji Nishijima, Ken-Ichi Shukunami, Hirokazu Tsukahara, Fumikazu Kotsuji, G. Kayem, C. Davy, F. Goffinet, C. Thomas, D. Clément, D. Cabrol

    Obstetrics and Gynecology   105 ( 1 )   219 - 221   2005.1

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    DOI: 10.1097/01.AOG.0000150443.23143.fc

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  • Conservative versus extirpative management in cases of placenta accreta

    K Nishijima, K Shukunami, H Tsukahara, F Kotsuji

    OBSTETRICS AND GYNECOLOGY   105 ( 1 )   220 - 220   2005.1

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    DOI: 10.1097/01.AOG.0000149162.89941.83

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  • An additional approach of repeat digital examination for preterm labor: comment on Volumenie et al

    k.Shukunami, K.Nishijima, K.Tajima, Y.Yoshida, F.Kotsuji

    Europ J Obstet Gynecol Reprod Biol   117   33 - 37   2005

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  • Natural history of bacterial vaginosis and intermediate flora in pregnancy and effect of oral clindamycin

    K Nishijima, K Shukunami, F Kotsuji

    OBSTETRICS AND GYNECOLOGY   104 ( 5 )   1106 - 1107   2004.11

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    DOI: 10.1097/01.AOG.0000145332.52142.d3

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  • 出生前診断し得た巨大絨毛膜下血腫の1例

    津吉 秀昭, 西島 浩二, 宿南 憲一, 吉田 好雄, 後藤 健次, 小辻 文和

    日本産科婦人科学会東北連合地方部会誌   ( 51 )   128 - 129   2004.3

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  • 妊産婦におけるProbiotics

    西島 浩二, 宿南 憲一, 津吉 秀昭, 宮崎 ミカ, 久住 健一, 小辻 文和

    日本産科婦人科学会雑誌   56 ( 2 )   488 - 488   2004.2

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  • 開腹下における癒着胎盤子宮温存法の工夫

    有倉 清香, 西島 浩二, 宿南 憲一, 吉田 好雄, 小辻 文和

    日本産科婦人科学会雑誌   56 ( 2 )   681 - 681   2004.2

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    Other Link: https://projects.repo.nii.ac.jp/?action=repository_uri&item_id=434670

  • 13-19.妊産婦におけるProiotics(第62群 妊娠・分娩・産褥期14)(一般講演)

    西島 浩二, 宿南 憲一, 津吉 秀昭, 宮崎 ミカ, 久住 健一, 小辻 文和

    日本産科婦人科學會雜誌   56 ( 2 )   488 - 488   2004

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  • プロバイオティックLC1の妊産婦に与える影響

    西島 浩二, 宿南 憲一, 小辻 文和

    母性衛生   44 ( 3 )   137 - 137   2003.9

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  • 巨大絨毛膜下血腫により子宮内胎児死亡を来たした症例

    西島 浩二, 福田 真

    日本新生児学会雑誌   39 ( 2 )   350 - 350   2003.6

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  • 血液透析中の臍帯動脈血流計測が胎児ジストレスの早期発見に有用であった1症例

    折坂 早苗, 宿南 憲一, 西島 浩二, 折坂 誠, 小辻 文和, 山本 智恵, 鈴木 亨

    日本妊娠中毒症学会雑誌   10   151 - 152   2002.12

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  • 原因不明不育症に対する低分子ヘパリン及び低用量アスピリン療法の有用性について

    折坂 早苗, 折坂 誠, 八木原 亮, 西島 浩二, 西川 有紀子, 黒川 哲司, 打波 郁子, 河原 和美, 宿南 憲一, 吉田 好雄

    日本産科婦人科学会雑誌   54 ( 2 )   422 - 422   2002.2

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  • 帝王切開瘢痕部妊娠の一症例

    西島 浩二, 吉井 久美子, 福田 真, 金嶋 光夫, 紙谷 尚之

    日本産科婦人科学会東北連合地方部会報   ( 48 )   115 - 115   2001.3

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  • 帝王切開術後に発症し診断に苦慮した血球貪食症候群の1例

    西島 浩二, 内田 季之, 辻 隆博, 金嶋 光夫, 紙谷 尚之

    日本産科婦人科学会東北連合地方部会報   ( 47 )   95 - 95   2000.3

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  • 胎脂によるNeonatal Aspiration Syndromeの1例

    古畑 律代, 内田 英夫, 井上 修司, 西島 浩二, 中井 昭夫

    日本未熟児新生児学会雑誌   10 ( 3 )   465 - 465   1998.9

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Presentations

  • 早産期の消化管保護に向けた治療戦略~肺サーファクタントと胎脂に着目して~

    西島 浩二

    第7回ペリネイタル研究会  2019.10 

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  • 次回妊娠を見据えた帝王切開術の工夫 Invited

    西島 浩二

    第34回新潟産科婦人科手術・内視鏡下手術研究会  2019.2 

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  • 妊娠高血圧症候群に関連した中枢神経障害 Invited

    西島 浩二

    第59回日本母性衛生学会総会・学術集会  2018.10 

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  • 次回妊娠を見据えた安全な帝王切開術の工夫 Invited

    西島 浩二

    青森産婦人科小グループ勉強会  2018.7 

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  • 次回妊娠を見据えた安全な帝王切開術の工夫 Invited

    西島 浩二

    第46回北陸産科婦人科学会学術講演会ランチョンセミナー  2018.6 

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  • 福井県における周産期医療の現状と今後の医療分担のあり方 Invited

    西島 浩二

    福井県小児科医会教育研修  2018.3 

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  • 前置癒着胎盤に対する子宮底部横切開法

    西島 浩二

    第25回日本胎盤学会学術集会 第35回日本絨毛性疾患研究会 ワークショップ「胎盤異常の診断と管理」  2017.11 

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  • HTLV-1母子感染対策 ~支えよう、母と子の未来を~

    西島 浩二

    福井県母子保健研修会HTLV-1講演会  2017.10 

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  • 早産児の消化管保護に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    西島 浩二

    第53回日本周産期・新生児医学会学術集会 ミニシンポジウム  2017.7 

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  • 産婦人科医としての23年、医学部教員としての16年の経験から、皆さんに伝えたいこと

    西島 浩二

    福井県立高志高校講演 卒業生と語る会  2017.6 

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  • 帝王切開術の工夫とトラブルへの対策

    西島 浩二

    ジョンソン・エンド・ジョンソン社内講演会インタビュー  2017.6 

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  • セプラと帝切と私

    西島 浩二

    科研製薬株式会社京滋北陸営業部エリア社内講演会  2017.6 

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  • トラブルを未然に防ぐための帝王切開術の工夫

    西島 浩二

    第8回びわこ周産期研究会  2016.8 

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  • 子宮底部横切開法の工夫

    西島 浩二

    第52回日本周産期・新生児医学会学術集会 ワークショップ  2016.7 

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  • 肺サーファクタントと胎脂を用いた消化管保護に向けての治療戦略

    西島 浩二

    第52回日本周産期・新生児医学会学術集会 ワークショップ  2016.7 

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  • 肺サーファクタントと胎脂は早産児の腸管を保護する~胎児期における肺-皮膚-消化器間相互作用の解明を目指して~

    西島 浩二

    第68回日本産科婦人科学会学術講演会 ミニワークショップ  2016.4 

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  • 災害時における妊産婦への対応

    西島 浩二

    平成27年度専門医認定支援事業 杉田玄白記念公立小浜病院講演会  2016.3 

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  • 帝王切開術後骨盤内膿瘍の予防に向けた当院の治療戦略

    西島 浩二

    第28回日本外科感染症学会総会学術集会 シンポジウム  2015.12 

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  • 帝王切開における子宮創部癒合不全の防止法

    西島 浩二

    第30回日本女性医学学会学術集会 スポンサードセミナーシンポジウム  2015.11 

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  • 胎脂の謎に迫る!生まれたての赤ちゃんを包む白いベトベトの秘密

    西島 浩二

    第32回石川県母性衛生学会・第30回北陸母性衛生学会学術総会 特別講演  2015.7 

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  • 帝王切開術の工夫とトラブルへの対策

    西島 浩二

    第128回関東連合産科婦人科学会総会・学術集会  2014.9 

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  • 超低出生体重児の消化管保護に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    西島 浩二

    第1回新潟産婦人科シンポジウム  2014.9 

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  • 超低出生体重児の消化管保護に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    西島 浩二

    第1回北信越産婦人科研究会  2014.7 

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  • 正常血圧でreversible posterior leukoencephalopathy syndromeを発症し産褥子癇と最終診断した一例

    第66回日本産科婦人科学会学術講演会  2014 

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  • 急性白血病合併妊娠3症例の報告

    第27回福井県母性衛生学会総会ならびに学術集会  2014 

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  • 分娩監視装置からの心音データを用いた胎児の心拍RR時間のリアルタイム計測システムの試作

    日本音響学会2014年6月聴覚研究会  2014 

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  • 神経線維腫症に合併した褐色細胞腫による高血圧クリーゼを契機に発症した心肺虚脱型羊水塞栓症の1例

    第66回日本産科婦人科学会学術講演会  2014 

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  • 子宮内反症と子宮破裂を併発し子宮の完全反転を認めた一例

    第42回北陸産科婦人科学会学術講演会  2014 

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  • 子宮頸癌の脈管侵襲陽性のみは再発リスク因子となるか-組織型の違いによる検討-

    第22回福井婦人科腫瘍研究会  2014 

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  • Prenatal diagnosis of congenital myotonic dystrophy in the third trimester of pregnancy using ultrasouography

    25th Annual Meeting of Asia-Pacific Endocrine Conference(APEC)  2014 

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  • 羊水過多症とgrip myotonia(把握性筋緊張)

    福井県産婦人科医師連合第77回冬期臨床研修会  2014 

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  • 超低出生体重児の消化管機能成熟に向けた治療戦略:胎児肺-皮膚-消化管間相互作用の解明を目指して

    第66回日本産科婦人科学会学術講演会  2014 

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  • 臍帯卵膜付着の2症例

    母体保護法指定医師研修会ならびに福井県産婦人科医師連合第78回夏期臨床研修会  2014 

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  • 先天性筋緊張性ジストロフィーが推測される胎児の超音波診断

    第50回日本周産期・新生児医学会学術集会  2014 

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  • 痩せ型妊婦の栄養管理の取り組み

    第27回福井県母性衛生学会総会ならびに学術集会  2014 

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  • 妊娠19週にARB内服を中止したが無羊水症が遷延し、中期中絶が選択された一例

    第62回北日本産科婦人科学会総会・学術講演会  2014 

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  • 妊娠後期における筋緊張性ジストロフィー合併妊娠の胎児超音波診断

    第62回北日本産科婦人科学会総会・学術講演会  2014 

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  • 遺伝性QT延長症候群合併妊娠の1例

    第28回北陸周産期・新生児研究会  2014 

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  • Marginal insertion with Velamentous vessel の臨床像

    第22回日本胎盤学会学術集会 第32回日本絨毛性疾患研究会  2014 

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  • 帝王切開後に子宮筋層切開部感染を生じた4症例

    第50回日本周産期・新生児医学会学術集会  2014 

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  • 超低出生体重児の消化管機能成熟に向けた治療戦略:胎児肺-皮膚-消化管間相互作用の解明を目指して

    第50回日本周産期・新生児医学会学術集会  2014 

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  • 超低出生体重児の消化管成熟に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    西島 浩二

    福井県周産期検討会  2013.10 

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  • 超低出生体重児の消化管成熟に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    西島 浩二

    社会医療法人愛仁会高槻病院研修会 第35回周産期公開カンファレンス「胎児消化管の機能・発育を考える」  2013.7 

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  • 既往帝切切開術後妊娠におけるVBAC例の検討

    第65回日本産科婦人科学会学術講演会  2013 

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  • 交通外傷後に子宮内胎児死亡に至った一例

    第41回北陸産科婦人科学会学術講演会  2013 

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  • A nobel treatment strategy for the gastrointestinal development of extremely premature infants:administration of micelles derived from pulmonary surfactants and the vernix caseosa in pregnant rabbits.

    XI Warld congress of perinatal medicine(WCPM)  2013 

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  • 子宮発育不全症の妊娠は極めてリスクが高い

    第41回北陸産科婦人科学会学術講演会  2013 

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  • 当院における子宮内膜細胞診に液状検体法を導入した子宮体癌のスクリーニング法の現状

    第65回日本産科婦人科学会学術講演会  2013 

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  • 褐色細胞腫に伴う内分泌異常(高血圧クリーゼ)トの鑑別に苦慮した羊水塞栓症の1例

    福井県産婦人科医会第75回冬期臨床研修会  2013 

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  • A retrospective review of velamentous cord insertion.

    XI Warld congress of perinatal medicine(WCPM)  2013 

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  • 神経線維腫症合併の褐色細胞腫に起因する高血圧クリナーゼを契機に発症した心肺虚脱型羊水塞栓症の1例

    第26回福井県母性衛生学会総会ならびに学術講演会  2013 

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  • 交通事故後に子宮内胎児死亡に至った一例

    第61回北日本産科婦人科学会総会・学術講演会  2013 

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  • 当院におけるTOLAC症例の検討

    第61回北日本産科婦人科学会総会・学術講演会  2013 

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  • 胎児消化管の機能・発育を考える

    第35回周産期公開カンファレンス  2013 

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  • 神経線維腫症に合併した褐色細胞腫クリーゼを契機に発症した心肺虚脱型羊水栓塞症の1例

    第49回日本周産期・新生児医学会学術集会  2013 

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  • 神経線維腫症に合併した褐色細胞腫による高血圧クリーゼを契機に発症した心肺虚脱型羊水栓塞症の1例

    第61回北日本産科婦人科学会総会・学術講演会  2013 

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  • 娩出時期の設定に苦慮した品胎症例

    第61回北日本産科婦人科学会総会・学術講演会  2013 

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  • 児娩出時期の設定に苦慮した品胎症例

    第26回福井県母性衛生学会総会ならびに学術講演会  2013 

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  • 交通事故後に子宮内胎児死亡に至った一例

    第26回福井県母性衛生学会総会ならびに学術講演会  2013 

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  • A retrospective review of velamentous cord insertion

    XI Warld congress of perinatal medicine(WCPM)  2013 

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  • 超低出生体重児の消化管成熟に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    西島 浩二

    日本肺サーファクタント・界面医学会第48回学術研究会  2012.10 

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  • Duchenne型筋ジストロフィーの出生前診断

    第14回遺伝性疾患に関する甲信越・北陸出生前診断研究会・第33回北陸臨床遺伝研究会  2012 

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  • 食道癌合併の1例

    第26回北陸周産期・新生児研究会  2012 

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  • 脳転移を伴った進行子宮体癌の治療

    第20回福井婦人科腫瘍研究会  2012 

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  • 妊娠子宮嵌頓症における診断のポイントと帝王切開の留意点

    第60回北日本産科婦人科学会総会・学術講演会  2012 

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  • 食道癌合併妊娠の1例

    福井県産婦人科医師連合第74回夏期臨床研修会  2012 

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  • 食道癌合併妊娠の1例

    第60回北日本産科婦人科学会総会・学術講演会  2012 

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  • 臍帯卵膜付着の後方視的検討

    第60回北日本産科婦人科学会総会・学術講演会  2012 

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  • IUD抜去後の骨盤内放線菌感染症

    第40回北陸産科婦人科学会総会・学術講演会  2012 

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  • 漿幕下筋腫が原因となった嵌頓子宮における帝王切開の留意点と診断のポイント

    福井県産婦人科医師連合第73回冬期臨床研修会  2012 

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  • 当院における臍帯付着部異常症例の検討

    第48回日本周産期・新生児医学会総会および学術集会  2012 

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  • 50症例の経験から「子宮底部横切開による帝切法」の有用性と問題点を考える~前置癒着胎盤に対する安全な手術法の確立を目指して~

    西島 浩二

    第33回日本産婦人科手術学会  2011.2 

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  • 重症妊娠高血圧腎症における新たな降圧指針作成の可能性~臍帯動脈血流速度波形からのアプローチ~

    第63回日本産科婦人科学会学術講演会  2011 

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  • 50症例の経験から「子宮底部横切開による帝切法」の有用性と問題点を考える~前置胎盤に対する安全な手術法の確立を目指して~

    第63回日本産科婦人科学会学術講演会  2011 

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  • 超低出生体重児の消化管成熟に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    第47回日本周産期・新生児医学会総会および学術集会  2011 

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  • 卵巣癌に対する試験開腹術後に胸水貯留をきたした一例

    福井県産婦人科医師連合第72回夏期臨床研修会  2011 

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  • 産婦人科医としての16年、医学部教員としての9年の経験から、皆さんに伝えたいこと

    西島 浩二

    福井県立高志高等学校 進路決定のための教育講座  2010.11 

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  • 広範囲な穿通胎盤症例の膀胱温存法:病的膀胱の修復とカテーテル留置による膀胱摘出の回避

    第62回日本産科婦人科学会学術講演会  2010 

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  • 重症妊娠高血圧腎症における 新たな降圧指針作成の可能性 臍帯動脈血流速度波形からのアプローチ

    第24回北陸周産期・新生児研究会  2010 

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  • 重症妊娠高血圧腎症に対する降圧剤の使い方~臍帯動脈血流速度波形からのアプローチ~

    第58回日本産科婦人科学会北日本連合地方部会総会・学術講演会 / 第38回日本産科婦人科学会北陸連合地方部会総会・学術講演会  2010 

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  • Usefulness of the transverse uterine fundal incision for placenta previa.

    The XXⅡ European Congress of perinatal Medicine  2010 

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  • 妊娠18週未満の前期破水に対する治療戦略:Cervical sealing(子宮頸部シール法)の開発

    第62回日本産科婦人科学会学術講演会  2010 

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  • HIV治療中にも認めた円錐切除後子宮頚部腺癌の一例

    第27回日本臨床細胞学会北陸支部連合会学術集会  2010 

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  • 2009H1N1インフルエンザの感染により急速に進行した早産症例の検討

    第46回日本周産期・新生児医学会総会および学術集会  2010 

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  • 妊娠18週未満に発症した前期破水の妊娠予後

    福井県産婦人科医会第69回冬期臨床研修会  2010 

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  • 安全で容易な腹膜外帝切法とトレーニング法の開発~反復帝切による腹膜内癒着回避の対策~

    第62回日本産科婦人科学会学術講演会  2010 

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  • 子宮体癌の術後診断と術前MRI評価との間に差異があった症例について

    福井県産婦人科医会第69回冬期臨床研修会  2010 

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  • ホルモン療法中に発症した若年性脳梗塞の1例

    福井県産婦人科医会第69回冬期臨床研修会  2010 

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  • FES-PETを用いた筋腫内ER評価の有用性:妊娠中の筋腫サイズ変化の予測のために

    第57回日本産科婦人科学会北日本連合地方部会総会・学術講演会  2009 

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  • Ureaplasma urealyticum感染が病因と考えられ、呼吸管理に難渋したWilson-Mikity症候群の1例

    第45回中部日本小児科学会  2009 

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  • 子宮頚部腺癌合併妊娠の1例

    第46回日本婦人科腫瘍学会学術集会  2009 

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  • 深部静脈血栓症(DVT)を合併する進行卵巣癌の治療方針~DVTの急激な進行により緊急開腹を要した症例の治療経験から~

    第37回日本産科婦人科学会北陸連合地方部会総会ならびに学術講演会  2009 

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  • 妊娠経過中に著名な縮小を認めた子宮筋腫合併妊娠の1例

    第61回日本産科婦人科学会総会・学術講演会  2009 

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  • 痩せと妊娠:巨大な胎盤低エコー像とIUGRを呈した症例

    第57回日本産科婦人科学会北日本連合地方部会総会・学術講演会  2009 

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  • 18週未満に発症した破水症例の妊娠転帰とCervical sealingの是非

    第57回日本産科婦人科学会北日本連合地方部会総会・学術講演会  2009 

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  • 二絨毛膜性双胎におけるDelayed interval deliveryの経験

    福井県産婦人科医会第68回夏期臨床研修会  2009 

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  • 拡散強調画像(MRI)の子宮頸癌診療への導入の試み-子宮頚癌7例の検討結果-

    第17回福井婦人科悪性腫瘍研究会  2009 

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  • 病的膀胱の修復とカテーテル留置により膀胱摘出を回避できた穿通胎盤症例

    第32回日本産婦人科手術学会  2009 

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  • 反復帝切による腹腔内癒着回避のために~我々が行う腹膜外帝切とトレーニング法の実際

    第32回日本産婦人科手術学会  2009 

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  • 帝切後子宮縫合不全を修復した後に妊娠、出産となった1症例

    第32回日本産婦人科手術学会  2009 

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  • 2絨毛膜双胎におけるDelayed interval deliveryの経験

    第23回北陸周産期・新生児研究会  2009 

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  • 変形する胎盤低エコー像を呈した症例

    第17回日本胎盤学会学術集会  2009 

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  • 18週未満に発症した破水症例の妊娠転帰とCervical sealingの是非

    第23回北陸周産期・新生児研究会  2009 

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  • アンドロゲン過剰症がその原因と推測された子宮頸管無力症の1例

    第61回日本産科婦人科学会総会・学術講演会  2009 

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  • 1st trimesterに発生したearly preterm PROMに対してcervical sealingが奏功した一例

    福井県産婦人科医会第67回冬期臨床研修会  2009 

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  • Ureaplasma urealyticum感染が病因と考えられ呼吸管理に難渋したWilson-Mikity症候群の1例と、当院における極低出生体重児の血清KL-6値についての検討

    第15回未熟児新生児医療研究会  2009 

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  • 膀胱浸潤を伴った前置癒着胎盤の1例

    第424回日本泌尿器科学会北陸地方会  2009 

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  • 超低出生体重児の消化管成熟に向けた治療戦略:肺サーファクタントを用いた動物実験

    西島 浩二

    第44回日本周産期・新生児医学会総会および学術集会  2008.7 

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  • ここまで進んだ産科医療

    西島 浩二

    第49回福井県婦人福祉協議会講演「産婦人科医から一般の皆さんに伝えたいこと」  2008.6 

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  • ここまで進んだ産科医療

    西島 浩二

    坂井市食生活改善推進員・母子保健推進員合同研修会 ココロとからだを軽くする公開講演会「産婦人科医から一般の皆さんに伝えたいこと」  2008.5 

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  • ここまで進んだ産科・周産期医療

    西島 浩二

    勝山市母子保健事業 公開講演会  2008.4 

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  • 未熟子宮妊娠

    第44回日本周産期・新生児医学会総会および学術集会  2008 

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  • 超音波ドプラ法によるPerinasal fluid flowの観察:胎児診断、特に出生後の呼吸機能予測への応用

    第60回日本産科婦人科学会総会・学術講演会  2008 

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  • エストロゲン受容体イメージング製剤(16α-[<SUP>18</SUP>F]-fluoro-17βestradiol(FES))を用いたポジトロン断層(PET)検査の婦人科腫瘍診断導入に向けた研究

    第60回日本産科婦人科学会総会・学術講演会  2008 

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  • 子宮頸癌合併妊娠の一例

    第65回福井県産婦人科医会冬期臨床研修会  2008 

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  • 多発性肝転移に肝動注塞栓術が奏功した、子宮頸部atypical carcinoidの一例

    第36回日本産科婦人科学会北陸連合地方部会総会ならびに学術講演会  2008 

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  • 高TG血症合併妊婦の1例

    第21回福井県母性衛生学会総会・学術講演会  2008 

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  • 小児白血病治療後の妊娠時に発症した児頭変形と子宮破裂

    第21回福井県母性衛生学会総会・学術講演会  2008 

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  • 子宮内膜細胞診で不適切検体を減らすには?~採取器具の違いによる検討~

    第16回福井婦人科悪性腫瘍研究会  2008 

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  • 前置胎盤に対する子宮体部横切開法の有用性

    第36回日本産科婦人科学会北陸連合地方部会総会ならびに学術講演会  2008 

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  • 前置癒着胎盤および広範な前壁付着を伴う前置胎盤に対する新たな帝切法:子宮底部横切開法の安全性と有用性

    西島 浩二

    第17回日本産婦人科・新生児血液学会  2007.6 

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  • 多胎妊娠を防ぐには~多胎妊娠中絶例からの考察~

    第63回福井県産婦人科医会冬期臨床研修会  2007 

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  • 前置癒着胎盤及び広範な前壁付着を伴う前置胎盤に対する新たな帝切法:子宮底部横切開法の安全性と有用性

    第59回日本産科婦人科学会総会・学術講演会  2007 

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  • 胎児期より経過観察されている巨大尿管症の女児例

    第12回福井腎疾患研究会  2007 

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  • 子宮頸癌におけるFDG PETの役割

    第11回福井大学高エネルギー医学研究センター研究会  2007 

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  • 福井大学病院における内視鏡手術の現状と問題点

    第1回福井産婦人科研究会  2007 

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  • ヒトにおけるL-arginine/NOS/NO系とPRMT/ADMA/DDAH系のバランスの生理学的意義について

    第16回発達腎研究会  2007 

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  • 大腸癌合併妊娠の診断にMRIが有用であった症例

    第35回日本産科婦人科学会北陸連合地方部会総会ならびに学術講演会  2007 

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  • 子宮頸がんにおけるPET診断

    第15回福井婦人科悪性腫瘍研究会  2007 

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  • 婦人科内視鏡手術における満足・不満足度調査

    第20回福井県母性衛生学会総会・学術講演会  2007 

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  • エストロゲン受容体イメージング製剤(16α-[18F]-fluoro-17βestradiol(FES))を用いたポジトロン断層(PET)検査の婦人科腫瘍診断導入に向けた研究

    JSAWI(The Japanese Society for the Advancement of Women’s Imaging)2007  2007 

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  • Influence of adnexal torsion on tubal functions in rabbits

    Fourth Canada-Japan Bilateral Workshop on Human Reproduction & Reproductive Biology  2007 

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  • 妊娠中にHypertriglycemia-induced pancreatitisを発症し、急激な増悪を来たした症例

    第21回北陸周産期・新生児研究会  2007 

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  • 子宮鏡手術における満足・不満足度調査

    第64回福井県産婦人科医会夏期臨床研修会  2007 

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  • エストロゲン受容体イメージング製剤(16α-[18F]-fluoro-17βestradiol(FES))を用いたポジトロン断層(PET)検査の婦人科腫瘍診断導入に向けた研究

    第55回日本産婦人科学会北日本連合地方部会総会ならびに学術講演会  2007 

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  • 前置癒着胎盤及び広範な前壁付着を伴う前置胎盤に対する新たな帝切法:子宮底部横切開法の安全性と有用性

    第55回日本産婦人科学会北日本連合地方部会総会ならびに学術講演会  2007 

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  • 妊娠初期よりIUGRを呈した4p症候群の一例

    第28回北陸先天異常研究会  2007 

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  • 子宮鏡手術トレーニングの工夫~割り箸レゼクトスコープを用いたTCR訓練~

    第47回日本産科婦人科内視鏡学会学術講演会  2007 

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  • 肺サーファクタントがウサギ胎仔小腸上皮の成熟に与える影響

    第4回福井大学生殖生物学ユニット合同セミナー  2006 

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  • 前置癒着胎盤を疑う症例に対する術式の工夫~子宮底部横切開を中心に

    第8回北信越北潟湖セミナー  2006 

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  • 子宮頸部円錐切除術に対するHarmonic scalpelの使用経験

    第34回日本産科婦人科学会北陸連合地方部会総会ならびに学術講演会  2006 

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  • 生直後に著明な赤芽球増加、低血糖を呈した極低出生体重児例: エリスロポイエチン(Epo)高値の生体応答学的意義について

    第15回発達腎研究会  2006 

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  • 難治性不育症に対する抗凝固療法

    第61回福井県産婦人科医会冬期臨床研修会  2006 

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  • 心不全を来たしたpreeclampsia(妊娠高血圧腎症)例

    第61回福井県産婦人科医会冬期臨床研修会  2006 

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  • FDG-PETを用いた腫瘍ドックで発見された卵巣癌の1例

    第34回日本産科婦人科学会北陸連合地方部会総会ならびに学術講演会  2006 

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  • 胎児期にPotter sequenceを疑われ、出産後urosepsisを呈した多発性嚢腎の1例

    第35回京都腎臓免疫研究会  2005 

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  • 肺サーファクタントはウサギ胎仔小腸上皮を成熟させる‐胎児肺-消化管間interaction解明への試み

    第57回日本産科婦人科学会学術講演会  2005 

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  • PCOのfollow up中に発見された若年性子宮体癌の一例

    第22回日本臨床細胞学会福井県支部総会並びに学術集会  2005 

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  • Kimematic MRIによる産褥子宮の機能的評価の試み

    第16回福井MR研究会  2005 

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  • Kinematic MRIによる産褥子宮の機能的評価

    第57回日本産科婦人科学会学術講演会  2005 

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  • 妊娠初期の胎盤辺縁角測定による分娩期前置胎盤の予測

    第57回日本産科婦人科学会学術講演会  2005 

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  • 胎児期から青年期にかけてのAdvanced glycation end-products生成の評価

    第14回発達腎研究会  2005 

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  • 子宮内膜細胞診38診におけるThinlayer標準導入のメリット、デメリット-細胞採取~検体処理~検体の精度まで-

    第21回福井県臨床細胞学会 福井支部総会並びに学術集会  2004 

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  • 妊産婦におけるproiotics

    第56回日本産科婦人科学会学術講演会  2004 

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  • 開腹下における癒着胎盤子宮温存法の工夫

    第56回日本産科婦人科学会学術講演会  2004 

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  • 骨軟骨異形成症の超音波診断

    第52回日本産科婦人科学会北日本連合地方部会総会・学術大会  2004 

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  • 診断、治療に難渋した高齢女性の子宮留膿症の3例

    第32回日本産科婦人科学会北陸連合地方部会  2004 

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  • 高度肥満妊婦の帝王切開術

    第52回日本産科婦人科学会北日本連合地方部会総会・学術大会  2004 

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  • 卵巣癌におけるPET検査のFDG集積能は、悪性度に相関する

    第12回福井婦人科悪性腫瘍研究会  2004 

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  • 突然の子宮内胎児死亡に至った劇症1型糖尿病症例-尿中ケトン体陽性例の取り扱いについて-

    第52回日本産科婦人科学会北日本連合地方部会総会・学術大会  2004 

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  • プロバイオテックスLC1の妊産婦に与える影響

    第16回福井県母性衛生学会  2003 

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  • 巨大絨網膜下血腫により子宮内胎児死亡を来たした症例

    第39回日本新生児学会  2003 

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  • 分娩直後から寝ている褥婦には要注意

    第16回福井県母性衛生学会  2003 

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  • 出生前診断し得た巨大絨毛膜下血腫の1例

    第51回日本産婦人科学会北日本連合地方部会総会  2003 

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  • 出生診断し得た巨大絨毛膜下血腫の1例

    第31回日本産科婦人科学会北陸連合地方部会  2003 

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Industrial property rights

  • 心拍状態解析装置

    荒木 睦大, 森 幹男, 谷口 秀次, 小越 康宏, 西島 浩二, 白井 冶彦

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    Applicant:国立大学法人福井大学

    Application no:特願2014-117111  Date applied:2014.6

    Announcement no:特開2015-229030  Date announced:2015.12

    Patent/Registration no:特許第6403311号  Date registered:2018.9  Date issued:2018.10

    J-GLOBAL

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  • 腸管機能亢進剤とこれを用いた壊死性腸炎の治療または予防方法

    西島 浩二, 小辻 文和, 宿南 憲一

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    Applicant:国立大学法人福井大学

    Application no:特願2005-219695  Date applied:2005.7

    Announcement no:特開2007-031387  Date announced:2007.2

    Patent/Registration no:特許第4378531号  Date issued:2009.10

    J-GLOBAL

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  • 腸管機能亢進剤とこれを用いた壊死性腸炎の防止方法

    西島 浩二, 小辻 文和, 宿南 憲一

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    Applicant:国立大学法人福井大学

    Application no:特願2005-219695  Date applied:2005.7

    Announcement no:特開2007-031387  Date announced:2007.2

    J-GLOBAL

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Works

  • 妊産婦におけるプロバイオティクス:貪食細胞活性への影響および早産予防の可能性

    2001

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Awards

  • 福井大学医学部 2013年度前期教員等による優秀論文賞

    2013  

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  • 第64回日本産科婦人科学会学術講演会 最優秀演題賞

    2012  

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    Country:Japan

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  • 第57回日本産科婦人科学会・学術講演会 優秀演題賞受賞 (学会賞)

    2005  

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    Country:Japan

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Research Projects

  • 糖代謝異常合併妊娠の母児フォローアップに関するオール新潟レジストリーの構築

    Grant number:24K14791

    2024.4 - 2029.3

    System name:科学研究費助成事業

    Research category:基盤研究(C)

    Awarding organization:日本学術振興会

    山田 貴穂, 曽根 博仁, 西島 浩二, 小川 洋平, 藤原 和哉, 柳生田 紀子

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    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

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  • 早産児の消化管成熟に向けた治療戦略:肺サーファクタントと胎脂の生理活性に着目して

    Grant number:23H03040

    2023.4 - 2027.3

    System name:科学研究費助成事業 基盤研究(B)

    Research category:基盤研究(B)

    Awarding organization:日本学術振興会

    西島 浩二

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    Grant amount:\18590000 ( Direct Cost: \14300000 、 Indirect Cost:\4290000 )

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  • Analysis of the polymorphisms of genes coding biotransformation enzymes in fetal growth restriction

    Grant number:20K10448

    2020.4 - 2023.3

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

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    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

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  • A treatment strategy for gastrointestinal development of premature infants: Administration of micelles derived from pulmonary surfactants and vernix caseosa in a pregnant animal model

    Grant number:20K09595

    2020.4 - 2023.3

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

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    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

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  • A treatment strategy for gastrointestinal development of extremely premature infants: Administration of micelles derived from pulmonary surfactants and vernix caseosa in a pregnant animal model

    Grant number:17K11224

    2017.4 - 2020.3

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    Nishijima Koji

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    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

    We prepared 125I-labeled bovine pulmonary surfactant TA (STA; Mitsubishi Tanabe Pharma Corp., Osaka, Japan) using 125I-Succinimidyl-3-iodobenzoate. We then infused the 125I-labeled STA into the amniotic fluid space of pregnant Japanese white rabbits on gestational day 27 (right-ovarian-end fetuses). The 125I-labeled STA were transferred to maternal blood at 30 minutes post-dose, and most were excreted in the urine. The 125I-labeled STA were also transferred to all internal organs of all fetuses, and especially, highly accumulated at fetal stomach, gastric juices, and intestine. We speculate that the existence of highly-concentrated pulmonary surfactants in the neonatal gastrointestinal tracts just after the birth is important for neonatal immunocompetence acquisition processes. Although further studies are needed, our findings elucidate the physiological interactions among pulmonary, dermal-epidermal, and gastrointestinal developmental processes.

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  • 母親と胎児の瞬時心拍細変動解析機能を有する分娩監視装置の開発

    2017

    System name:平成29年度京都大学医学部附属病院臨床研究総合センター研究助成 平成29年度橋渡し研究戦略的推進プログラム シーズA

    西島 浩二

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    Authorship:Principal investigator  Grant type:Competitive

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  • An Evaluation to Develop the Fetal Heart Analysis Device by Using Sounds Signal of Fetal Heart

    Grant number:15K15600

    2015.4 - 2018.3

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research

    Research category:Grant-in-Aid for Challenging Exploratory Research

    Awarding organization:Japan Society for the Promotion of Science

    TAMAMURA CHIYO

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    Grant amount:\3640000 ( Direct Cost: \2800000 、 Indirect Cost:\840000 )

    The technique of analyzing Fetal Heart Rate (FHR) variability has been known to be effective to diagnose the fetal health condition in detail. In order to analyze the FHR variability, it is necessary to develop the method of measuring accurately the FHR, which corresponds to RR-interval in case of ECG, using fetal heart sounds. In this paper, the experimental results of the denoizing the fetal heart sounds obtained by ultrasound cardiograph, using multiresolution analysis method of discrete wavelet transformation, are described, and the effectiveness of the several points which are (1) the level of multiresolution analysis, (2) the sort of mother wavelets, and (3) the change of spectrum by denoizing process, are discussed.
    Furthermore, the method to automatically derive the RR time interval from waveforms of fetal heart sounds and the patent to measure fetal heat rate from umbilical cord artery, have been proposed in this study.

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  • A treatment strategy for the gastrointestinal development of extremely premature infants by administration of micelles derived from pulmonary surfactants and the vernix caseosa in pregnant rabbits

    Grant number:26462480

    2014.4 - 2017.3

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    Nishijima Koji

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    Grant amount:\4940000 ( Direct Cost: \3800000 、 Indirect Cost:\1140000 )

    We prepared 125I-labeled bovine pulmonary surfactant TA (STA; Mitsubishi Tanabe Pharma Corp., Osaka, Japan) using 125I-Succinimidyl-3-iodobenzoate. We then infused the 125I-labeled STA into the amniotic fluid space of pregnant Japanese white rabbits on gestational day 27 (right-ovarian-end fetuses). The 125I-labeled STA were transferred to maternal blood at 30 minutes post-dose, and most were excreted in the urine. The 125I-labeled STA were also transferred to all internal organs of all fetuses, and especially, highly accumulated at fetal stomach, gastric juices, and intestine. We speculate that the existence of highly-concentrated pulmonary surfactants in the neonatal gastrointestinal tracts just after the birth is important for neonatal immunocompetence acquisition processes. Although further studies are needed, our findings elucidate the physiological interactions among pulmonary, dermal-epidermal, and gastrointestinal developmental processes.

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  • PIH(妊娠高血圧症候群)症例における母体血中BNP値、NT-ProBNP値と周産期予後との関連

    2014

    System name:平成26年度トランスレーショナルリサーチ推進センター公募採択型研究費(学内共同研究)

    西島 浩二

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    Authorship:Principal investigator  Grant type:Competitive

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  • 新生児壊死性腸炎の克服に向けた治療戦略:肺サーファクタントと胎脂を用いた動物実験

    2013

    System name:平成25年度トランスレーショナルリサーチ推進センター公募採択型研究費(学内共同研究)

    西島 浩二

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  • Transverse uterine fundal incision for placenta previa accreta in the anterior wall

    Grant number:21592092

    2009 - 2011

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    KOTSUJI Fumikazu, YOSHIDA Yoshio, ORISAKA Makoto, KUROKAWA Tetsuji, NISHIJIMA Kouji, YOSHIDA Yoshio, ORISAKA Makoto, KUROKAWA Tetsuji

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    Grant amount:\3510000 ( Direct Cost: \2700000 、 Indirect Cost:\810000 )

    We developed an operative technique using a transverse uterine fundal incision to deliver infants in cases of placenta previa in the anterior uterine wall, with possible placenta accreta. This operative method overcomes the drawbacks associated with previous operative methods : fetal bleeding resulting from placental incision and blind manual removal of the placenta. This technique offers the following benefits. 1) The fetus can be delivered without any stress because incision into the placenta can be avoided perfectly. In addition, delivery from the apex of the highest part(usually breech) is both safe and simple. 2) The uterine cavity interior is visible and the trial of the placental removal can be done in full vision of the operator. 3) Throughout the procedure, bleeding from the myometrial wound can be stopped. 4) The uterine-wall incision can be extended without adding a cross section to the myometrium if the view of the uterine cavity is narrow. 5) The bleeding point from the placental bed is directly apparent. For that reason, precise hemostasis is possible. This operative method is much safer for mother and fetus and less stressful for operator than previously reported operative methods.

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  • 新生児壊死性腸炎に対する新たな治療戦略:肺サーファクタントを用いた動物実験.

    2009

    System name:平成21年度生命センター学内共同研究等

    西島 浩二

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  • A novel treatment strategy for gastrointestinal development of extremely low birth weight infants : Administration of micelles derived from pulmonary surfactants in a pregnant rabbit model

    Grant number:20591909

    2008 - 2010

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    NISHIJIMA Koji, TAKAHASHI Jin

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    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

    We have shown the presence of micelles derived from pulmonary surfactant in human full-term amniotic nuid. Micellization is also an important step in postnatal lipid absorption because fat is insoluble in the aqueous environment of the small intestinal lumen. Micelles exist in both amniotic fluid swallowed by the fetus and human breast milk ingested by neonates. Our study aimed to develop a new treatment strategy for gastrointestinal development of extremely low birth weight infants with a focus on the presence of micelles in the environment of fetus and neonates. We previously showed that continuous administration of micelles derived from pulmonary surfactants and vernix caseosa enhanced the development of the small intestine of the rabbit fetus.
    In our study, we used fluorescently labeled liposomes to show that micelles derived from pulmonary surfactant and vernix caseosa complex might directly and locally contribute to gastrointestinal development of the fetus. In addition, we developed a neonatal rat model to determine the potential beneficial effects of these micelles against necrotizing enterocolitis. Although further studies are required, our findings provide greater understanding of the physiologic interactions between the pulmonary, dermal-epidermal, and gastrointestinal development. One of the most critical issues in the early development of premature infants is the prevention and treatment of necrotizing enterocolitis. We expect that our study may contribute in improving the prognosis of premature infants.

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  • 超低出生体重児の消化管成熟に向けた治療戦略:肺サーファクタントを用いた動物実験

    2008

    System name:平成20年度重点配分経費

    西島 浩二

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  • 周産期におけるMycoplasma hominis, Ureaplasma urealyticum感染の早期スクリーニング法と超早産児の気管支肺異形成発症予防策の確立

    2008

    System name:平成20年度トランスレーショナルリサーチ推進センター公募採択型研究費

    西島 浩二

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  • 超低出生体重児の消化管成熟に向けた治療戦略:肺サーファクタントを用いた動物実験

    2007

    System name:競争的配分経費(研究評価に基づく配分経費)

    西島 浩二

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  • Influences of Adnexal Torsion on Tubal Functions in Rabbits

    Grant number:17591725

    2005 - 2006

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    SHUKUNAMI Ken-ichi, NISHIJIMA Koji, KOTSUJI Fumikazu, FUKUDA Shin, YOSHII Kumiko

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    Grant amount:\3500000 ( Direct Cost: \3500000 )

    Objective: Although the removal of adnexa has been the traditional surgery in torsion, recent reports have advocated conservative surgery, including detorsion, with follow-up. As conservative management has come to be increasingly selected, the effects of detorsion on the ovary have been widely studied. Nevertheless, to our knowledge, no studies have examined the tubal resistance to ischemia. This study was intended to demonstrate the effects of adnexal torsion on tubal histology and apoptotic changes using an animal model.
    Materials and Methods: We designed an adnexal torsion model using 16-week-old female Japanese White rabbits weighing approximately 3,000 g. A laparotomy was performed by midsagittal incision in the lower abdomen under an intravenous anesthesia of pentobarbital sodium salt. A puncture was made using a JELCO 22 G needle in the vascular area of the mesovaria; there the trocar was indwelled. An adnexal torsion was created by twisting the ovaries and tubes three times (1080°) using that trocar and then fixing on the peritonea with 3-0 vicryl. Following an ischemic period of 24, 72, 120, 240, or 720 h, the twisted adnexa were surgically removed and fixed for histopathological examination. The contralateral adnexa were used as controls.
    All specimens were fixed in 10% buffered formalin, embedded in paraffin, and stained with hematoxylin-eosin (HE) for histological examination. The specimens were also stained with TdT-mediated dUTP-biotin Nick End Labeling (TUNEL) to reveal the presence of cells that underwent apoptosis and were quantified according to the apoptosis score. Ultrastructural analyses of adnexas were also made using electron microscopy.
    Results: An examination was made of six rabbits in each group. Although operative death, attributed to respiratory depressant effect of pentobarbital sodium salt, occurred in two cases, no incomplete rabbit data existed except for those two.
    Although severe hemorrhage concealing ovarian parenchyma with infarct was prominent during 72 h torsion, the fallopian tubes showed no histological or ultrastructural changes even after 720 h torsion. Despite the above changes in the ischemic site, the histology of the contralateral adnexa was unaffected. As for the tubes, the apoptosis score showed no significant changes even after 720 h torsion.
    Discussion: We designed an animal model for adnexal torsion using 16-week-old rabbits. Fallopian tubes are highly resistant to ischemic damage caused by torsion. We assume that its subtle blood vessel control might support such a resistance. Furthermore, it is important to consider mammals' reproductive functions.
    Because histologically intact tubes were observed even after 720 h of ischemia in our animal model, it is likely that conservative therapy for adnexal torsion will preserve normal tubal function in spite of the ischemic insult. Although our results for rabbits cannot be inferred to be similar to those of humans, in many cases of uterine adnexal torsion, we can avoid salpingectomy. In conclusion, results of our study support the importance of conservative surgical management of tubes in adnexal torsion.

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  • 超低出生体重児の消化管成熟に向けた治療法の開発

    2005

    System name:競争的配分経費(研究評価に基づく配分経費)

    西島 浩二

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  • 超低出生体重児の消化管成熟に向けた治療法の開発:胎脂を用いた動物実験

    2004

    System name:平成16年度学部間学内共同研究への研究費配分

    西島 浩二

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  • 超低出生体重児の消化管成熟に向けた治療法の開発:胎脂を用いた動物実験

    Grant number:15659392

    2003 - 2004

    System name:科学研究費助成事業 萌芽研究

    Research category:萌芽研究

    Awarding organization:日本学術振興会

    西島 浩二, 宿南 憲一, 小辻 文和

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    Grant amount:\2600000 ( Direct Cost: \2600000 )

    1.肺サーファクタント製剤と胎脂を用いたミセルモデルの作成:
    1)肺サーファクタント製剤(サーファクテン【○!R】)は80g/ml以上の濃度でミセル分子を形成することを証明した。
    2)肺サーファクタント製剤とヒト胎脂の混合物が生理食塩水中でミセル分子を形成することを、電子顕微鏡観察(ネガティブ染色法)により証明した。
    以上は、肺サーファクタントとヒト胎脂がミセルを形成することを明らかにした初の報告である。
    2.ヒト羊水中のミセル分子の証明
    妊娠末期のヒト羊水中にはミセル分子が存在すること、しかしながら妊娠初期の羊水中には存在しないことを、同じく電子顕微鏡観察(ネガティブ染色法)により証明した。
    以上は、羊水中のミセル分子を観察した初の報告である。
    3.サーファクタント・ミセル投与が胎児腸管に及ぼす影響を検討するためのin vivo実験系作成
    妊娠ウサギ(New Zealand White種)の羊水腔内に、肺サーファクタント製剤と胎脂より作成した人工ミセルを注入するための動物実験系を作成した。開腹下にミニ浸透圧ポンプ(Alzet 2ML1)を、羊水腔内に留置し、一定流速でミセルモデルを注入する。対側子宮の羊水腔内には生理食塩水を注入し、コントロールとする。なお、侵襲を極力抑えるために、羊水腔内に留置するシングルカニューラを特別製作した。今後、手術手技に伴う流産率を抑えるためのさらなる工夫が必要である(現時点の流産率は37.5%)。

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  • Lactobacillus johnsonii LC1乳酸菌摂取によるヒト腸内フローラと腟内フローラの改善及び切迫早産、初乳IgAへの影響

    2003

    System name:乳酸菌応用研究会第2回特別研究助成

    西島 浩二

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  • A novel treatment strategy for intestinal development of the fetus: Administration of pulmonary surfactant micelles and vernix caseosa in animal models

    2002

    System name:Grant-in-Aid for Scientific Research

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    Grant type:Competitive

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  • Lactobacillus johnsonii LC1乳酸菌摂取によるヒト腸内フローラと腟内フローラの改善及び切迫早産、初乳IgAへの影響

    2002

    System name:乳酸菌応用研究会第1回研究助成

    西島 浩二

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    Authorship:Principal investigator  Grant type:Competitive

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Teaching Experience

  • 周産期病態論

    2023
    Institution name:新潟大学

  • 臨床医学講義(集中)

    2021
    Institution name:新潟大学