担当区分：筆頭著者   掲載種別：研究論文（学術雑誌）   出版者・発行元：Royal College of Psychiatrists  

DOI： 10.1192/j.eurpsy.2022.12

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担当区分：筆頭著者   記述言語：日本語   出版者・発行元：一般社団法人 日本認知・行動療法学会  

心理療法のエビデンスは介入前後の標的指標の差に基づくものが多く、その治療効果がどのように実施された結果得られたのかについて定量的な情報は乏しい。心理療法は言語を主手段とするが、近年、言語情報に対してデータ駆動型の計算アプローチによって客観的かつ再現可能なモデルを生成するトピックモデルが注目されている。本研究では、構造化された1事例の行動活性化中の会話データから、時系列構造を有する動的トピックモデルが治療セッション内容を抽出可能かについて検討を行った。結果として、会話に関する潜在的な四つのトピックが抽出され、それらの量的変動過程が治療プログラムを反映していることが示された。本研究は動的トピックモデルを心理療法中の会話に対して用いた最初の研究であり、これによる実際の治療プロセスの定量化と作用エビデンスの蓄積が期待できる。

DOI： 10.24468/jjbct.20-034

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担当区分：筆頭著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jad.2017.10.021

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1007/s00787-016-0842-5

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その他リンク： http://link.springer.com/article/10.1007/s00787-016-0842-5/fulltext.html

掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jpain.2026.106300

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掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jbct.2026.100599

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

BACKGROUND: Major depressive disorder (MDD), characterized primarily by mood disturbances, is also accompanied by abnormal cardiovascular functioning. However, the neuroanatomical substrates underlying this cardiovascular dysfunction remain elusive. METHODS: In this study, we investigated the neuroanatomical foundations of cardiac dysfunction in MDD. Using magnetic resonance imaging, we examined differences in gray matter volume (GMV) between patients with MDD (n = 81) and healthy control (HC) participants (n = 104) in regions implicated in cardiovascular regulation, notably the insula, anterior cingulate cortex (ACC), thalamus, and brainstem nuclei. Photoplethysmography signals acquired during a 10-minute resting state provided data to investigate group differences in heart rate variability (HRV) metrics (e.g., heart rate, low- and high-frequency components). Correlations and mixed-effect linear regression models tested the strength of group differences in the association between HRV metrics and regional GMV. Mediation analyses evaluated whether GMV mediated the observed group differences in HRV. RESULTS: Patients with MDD had faster heart rates and reduced HRV compared with HC participants. Neuroanatomically, patients with MDD manifested significantly reduced GMV across the insula, ACC, hippocampus, thalamus, and cerebellum. Negative correlations between insula GMV and HRV metrics were found in HC participants but not in patients with MDD. Regression models confirmed a stronger association between insula volume and HRV metrics in HC participants. Mediation analyses revealed that differences in cardiac measures explain the reduced insula GMV differences between diagnostic groups. CONCLUSIONS: These findings reveal a disrupted heart-brain relationship in MDD, notably a link between cardiac dysregulation and reduced insula volume. This highlights the importance of potential body-brain targets for therapeutic intervention in mood disorders.

DOI： 10.1016/j.biopsych.2026.03.997

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

PURPOSE: Subthreshold depression (StD), depressive symptoms below the diagnostic threshold for major depressive disorder (MDD), is associated with functional impairment and increased risk of MDD onset, but its physiological and cognitive characteristics remain unclear. This study aimed to identify objective markers of StD and validate predictive factors for MDD onset. PATIENTS AND METHODS: Among 168 university students, participants were classified into a StD group (n=87) and a healthy control group (n=81) using the Beck Depression Inventory-II (BDI-II). The StD group was further subdivided into "low depression" (BDI-II < 10, n = 21) and "maintained depression" (BDI-II ≥ 10, n = 66) based on their BDI-II scores at baseline. Assessments included voice characteristics, heart rate variability (HRV), peripheral body temperature, emotion recognition, and neurocognitive tasks. Between-group differences were tested using ANOVA and MANOVA, and participants were followed for MDD onset at 3-month intervals until March 2024. RESULTS: Compared to controls, the StD group showed increased vocal arousal (p = 0.007), elevated peripheral body temperature (p < 0.001), and reduced low-frequency HRV (p = 0.018). Sustained attention and executive function were impaired (p < 0.05). Accuracy in emotion recognition was lower for happy and surprised expressions (p = 0.030; p = 0.038). Subgroup analysis revealed more pronounced impairments in HRV, executive function, and emotion recognition in the maintained depression subgroup, which also had a higher MDD incidence (7 cases). In contrast, the low depression group showed selective attentional deficits and impaired emotion recognition, but no MDD onset. CONCLUSION: StD correlates with physiological and cognitive abnormalities reflecting MDD, and persistent symptoms suggest increased progression risk. These findings present candidate markers (voice arousal, HRV, body temperature, emotion recognition) for early identification and risk stratification; however, conclusions should be interpreted cautiously given the exploratory design.

DOI： 10.2147/NDT.S526034

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

BACKGROUND: Chronic pain imposes a substantial burden on individuals and society. Cognitive behavioral therapy for chronic pain (CBT-CP) has proven effective internationally, but randomized evidence in Japan is scarce. The first Japanese trial was a single-center, 16-session videoconference program that prioritized pain intensity. In contrast, this multicenter trial tests a brief, face-to-face, individualized CBT-CP program with quality of life (QoL) as the primary outcome. METHODS: This open-label, randomized, parallel-group superiority trial enrolls 60 adults aged 20-80 years with chronic pain persisting ≥ 3 months and EQ-5D-5L scores ≤ 0.80, indicating reduced QoL. Participants are randomized 1:1 to treatment as usual (TAU) plus an eight-session CBT-CP program or to a waitlist control receiving TAU only. The manualized intervention includes psycho-education, relaxation, activity pacing, and cognitive restructuring, delivered weekly face-to-face, with the goal of completing eight sessions within 14 weeks. If necessary, sessions may extend beyond the 15th week; however, the post-assessment is always conducted at 15 ± 2 weeks irrespective of intervention timing. Therapists meet prespecified eligibility criteria and receive structured training, supervision, and fidelity monitoring. The primary outcome is QoL (EQ-5D-5L) at 15 ± 2 weeks. Secondary outcomes include pain intensity, disability, depressive symptoms, catastrophizing, fear of movement, pain self-efficacy, and health-related QoL assessed by the SF-12. These outcomes, together with prognostic risk and somatic symptom burden, will also be examined as potential mediators or moderators. The intervention group undergoes a 27 ± 2-week follow-up to explore mid-term durability in a single-arm pre/post analysis. Analyses follow the intent-to-treat principle using linear mixed models, with effect sizes and confidence intervals reported; multiplicity will be considered in interpreting secondary outcomes. Blinding of participants and therapists is not feasible. DISCUSSION: This trial will clarify the added value of a brief, fidelity-assured, face-to-face CBT-CP program in Japan, where implementation remains limited. Findings are expected to guide clinical adoption, workforce training, and dissemination, while also generating hypotheses about for whom and through which processes CBT-CP may confer benefit. TRIAL REGISTRATION: University Hospital Medical Information Network Clinical Trials Registry, UMIN000042798. Registered on 21 December 2020, https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000048858 .

DOI： 10.1186/s13063-025-09153-6

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1007/s11548-025-03500-3

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier BV  

DOI： 10.1016/j.neunet.2025.107335

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Science and Business Media LLC  

DOI： 10.7759/cureus.75351

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

Subthreshold depression is a risk factor for depression among university students. Positive environmental reinforcement is a significant mediator of avoidance and depression in healthy university students. However, this relationship is understudied in those with subthreshold depression or depression. Therefore, this study examined these associations in healthy university students and those who fit the criteria for subthreshold depression or depression. We conducted an online survey with 1200 undergraduate students (600 women and 600 men, mean age = 20.61, SD = 1.59). The results revealed significant differences in avoidance patterns (behavioral social, behavioral nonsocial, cognitive social, and cognitive nonsocial), with participants with depression presenting the highest scores. The results of the mediation analysis were similar to those of previous studies in healthy groups. However, in the subthreshold-depression group, positive environmental reinforcement was mediated by behavioral social and behavioral non-social avoidance and depressive symptoms. In the group with depression, positive environmental reinforcement was mediated only by behavioral nonsocial avoidance and depressive symptoms. Associations between avoidance patterns, positive environmental reinforcement, and depressive symptoms vary with the degree of depressive symptoms. The results revealed by this study provide new foundational insights to prevent subthreshold depression among university students from deteriorating into depression.

DOI： 10.3390/bs14080713

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

BACKGROUND AND AIMS: Research suggests that various psychosocial factors influence chronic pain, with psychotherapies like cognitive behavioral therapy  proving effective. However, the limited availability and accessibility have prolonged suffering among patients with chronic pain. This challenge has led to a growing demand for accessible online interventions. We developed an online cognitive behavioral group therapy (CBGT) program, building upon our existing face-to-face CBGT program. We compared the scores obtained by patients during the treatment-as-usual (TAU) period with those collected at the beginning and at the end of the intervention. METHODS: Patients with chronic pain (N = 22) agreed to participate in the online CBGT program, which was conducted once a week for 12 sessions. The sample size was decided based on the effect sizes of our past face-to-face CBGT. We assessed pain intensity [Visual Analogue Scale (VAS)], pain catastrophizing [pain catastrophizing scale (PCS)] and psychiatric assessment [Beck Depression Inventory-Second Edition (BDI)-II], State-Trait-Anxiety Inventory (STAI), and Short Form Health Survey (SF-36) at three points: entry, pretreatment, and posttreatment. We also evaluated the participants' therapeutic alliance with the treatment staff [short-form version of the Working Alliance Inventory (WAI-S)]. We utilized analyses of variance, Friedman test, paired t-tests, Wilcoxon signed-rank test, and Pearson correlation analysis for data evaluation. RESULTS: Results indicated a significant posttreatment improvement in VAS, PCS, and BDI-II scores compared to the TAU period. Furthermore, posttreatment WAI-S scores increased significantly compared to pretreatment scores. Also, positive correlations were observed among pre- and posttreatment changes in WAI-S, pain intensity, and pain catastrophizing scores. CONCLUSION: There is a possibility that a therapeutic alliance can be established, and therapeutic effects achieved through an online CBGT intervention; however, additional research is required to substantiate this potential. We have registered this clinical trial in UMIN-CTR on 04/21/2021 with the number UMIN000043982.

DOI： 10.1002/hsr2.2141

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

INTRODUCTION: Depression is highly prevalent among university students. While behavioral activation has been shown to be an effective psychotherapy for depression, there is a lack of research regarding the behavioral activation mechanism. Furthermore, although self-compassion seems to be a factor in promoting behavioral activation, no studies have attempted to validate a behavioral activation model that includes positive self-compassion. In addition, mechanistic studies have lacked consideration in longitudinal studies of behavioral activation. Thus, in this longitudinal study, we constructed and validated an exploratory model of behavioral activation. METHODS: A total of 300 undergraduate students completed online surveys in 2019, 2020, and 2021. We examined the longitudinal effects of five factors (value-based behavior, goal-oriented and scheduled activities, positive reinforcement, self-compassion, and depressive symptoms) using structural equation modeling based on maximum likelihood estimation using bootstrapping. RESULTS: The exploratory model was found to be valid and to have a good fit with the data. The results indicate that value-based behaviors increase the frequency of goal-oriented and scheduled activities, which in turn increases the frequency of positive reinforcement in everyday life. Additionally, when self-compassion, value-based behavior, goal-oriented and scheduled activities, and positive reinforcement are considered together, self-compassion may be indirectly related to activation via value-based behavior. CONCLUSION: From the perspective of preventing depressive symptoms, it is important to increase the frequency of value-based activities. Furthermore, adding self-compassion is effective in behavioral activation to increase value-based activities. However, to address the limitations of this study, future studies should investigate the relationship among behavioral characteristics during interventions.

DOI： 10.1159/000538266

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

The integrated model of rumination argues that two trait factors-negative thinking habits and processing modes-get people stuck in maladaptive rumination. There is little evidence showing whether these factors influence the daily dynamic associations between rumination and negative moods. To address this, in this study, we conducted an experience-sampling method on Japanese university students. We recruited 92 Japanese university students and assessed their daily rumination and negative affect (NA) eight times a day for seven days. We examined the effects of habits and processing modes on the dynamic associations between rumination and negative moods using dynamic structural equation modeling. We found that individuals were more likely to ruminate when they experienced NA. However, contrary to previous findings, this study's participants did not experience NA after engaging in rumination. Moreover, we did not detect any significant trait factor effect on these dynamic associations. Our findings imply that individuals are more likely to engage in rumination after experiencing NA, but the reverse association, particularly the autoregression of rumination, may not be maintained in natural daily life. Furthermore, negative thinking habits and processing modes may not influence the daily dynamic associations between rumination and NA among Japanese university students.

DOI： 10.1038/s41598-024-55174-7

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記述言語：英語  

<jats:p>The objective diagnostic and stratification biomarkers developed with resting-state functional magnetic resonance imaging (rs-fMRI) data are expected to contribute to more effective treatment for mental disorders. Unfortunately, there are currently no widely accepted biomarkers, partially due to the large variety of analysis pipelines for developing them. In this study we comprehensively evaluated analysis pipelines using a large-scale, multi-site fMRI dataset for major depressive disorder (MDD) (1162 participants from eight imaging sites). We explored the combinations of options in four subprocesses of analysis pipelines: six types of brain parcellation, four types of estimations of functional connectivity (FC), three types of site difference harmonization, and five types of machine learning methods. 360 different MDD diagnostic biomarkers were constructed using the SRPBS dataset acquired with unified protocols (713 participants from four imaging sites) as a discovery dataset and evaluated with datasets from other projects acquired with heterogeneous protocols (449 participants from four imaging sites) for independent validation. To identify the optimal options regardless of the discovery dataset, we repeated the same procedure after swapping the roles of the two datasets. We found pipelines that included Glasser's parcellation, tangent-covariance, no harmonization, and non-sparse machine learning methods tended to result in high classification performance. The diagnosis results of the top 10 biomarkers showed high similarity, and weight similarity was also observed between eight of the biomarkers, except two that used both data-driven parcellation and FC computation. We applied the top 10 pipelines to the datasets of other mental disorders (autism spectral disorder: ASD and schizophrenia: SCZ) and eight of the ten biomarkers showed sufficient classification performances for both disorders, except two pipelines that included Pearson correlation, ComBat harmonization and random forest classifier combination.</jats:p>

DOI： 10.1101/2024.03.17.584538

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担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：研究論文（学術雑誌）  

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記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：日本行動医学会  

目的：新型コロナウイルス感染症の拡大により、特に精神医学の領域で遠隔医療が広く採用されるようになった。オンライン診療の効果を高めるためには、一般的なオンライン・コミュニケーションスキルを磨くことが不可欠である。そこで本研究では、テキスト分析を用いて、患者が共感的態度と認識できる医療者の応答の仕方と発話内容を明らかにすることを目的とした。方法：2021年12月から2022年2月にかけて医療者および一般人を研究対象者、模擬患者会のメンバーを研究補助者として模擬オンライン診療を実施した。参加者には医療者役を演じるように依頼した。研究補助者には、認知症の母親と同居し、不眠と疲労を経験している60代の女性患者役を演じてもらい、知覚された共感尺度(PES：Perceived Empathy Scale)への回答を依頼した。結果：患者役によって評価されたPES得点をもとに、医療者役を共感高群・中群・低群に分類した。またテキスト分析から、医療者の応答は4つのパターン(確認、疑問、共感、指示・助言)に、発話内容は8つのパターンに分類された。対応分析の結果から、応答の仕方については「確認」が共感高群で多くみられた。また発話内容については、「自身の身体不調」についての発話が共感高群で多くみられた。 考察：本研究では、望ましい医療者の態度について、実証的データを示した点で意義深い。結果から、相手の言ったことを繰り返す「確認」応答を多く行うこと、「患者自身の身体症状」に焦点を当てることが共感的態度として重要であることが示された。

DOI： 10.11331/jjbm.29.60

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

According to the operational diagnostic criteria, psychiatric disorders such as schizophrenia (SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder (ASD) are classified based on symptoms. While its cluster of symptoms defines each of these psychiatric disorders, there is also an overlap in symptoms between the disorders. We hypothesized that there are also similarities and differences in cortical structural neuroimaging features among these psychiatric disorders. T1-weighted magnetic resonance imaging scans were performed for 5,549 subjects recruited from 14 sites. Effect sizes were determined using a linear regression model within each protocol, and these effect sizes were meta-analyzed. The similarity of the differences in cortical thickness and surface area of each disorder group was calculated using cosine similarity, which was calculated from the effect sizes of each cortical regions. The thinnest cortex was found in SZ, followed by BD and MDD. The cosine similarity values between disorders were 0.943 for SZ and BD, 0.959 for SZ and MDD, and 0.943 for BD and MDD, which indicated that a common pattern of cortical thickness alterations was found among SZ, BD, and MDD. Additionally, a generally smaller cortical surface area was found in SZ and MDD than in BD, and the effect was larger in SZ. The cosine similarity values between disorders were 0.945 for SZ and MDD, 0.867 for SZ and ASD, and 0.811 for MDD and ASD, which indicated a common pattern of cortical surface area alterations among SZ, MDD, and ASD. Patterns of alterations in cortical thickness and surface area were revealed in the four major psychiatric disorders. To our knowledge, this is the first report of a cross-disorder analysis conducted on four major psychiatric disorders. Cross-disorder brain imaging research can help to advance our understanding of the pathogenesis of psychiatric disorders and common symptoms.

DOI： 10.1038/s41380-023-02224-7

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using the current diagnostic system based on presenting symptoms and signs. The creation of a novel diagnostic system using objective biomarkers is expected to take place. Neuroimaging studies and others reported that subcortical brain structures are the hubs for various psycho-behavioral functions, while there are so far no neuroimaging data-driven clinical criteria overcoming limitations of the current diagnostic system, which would reflect cognitive/social functioning. Prior to the main analysis, we conducted a large-scale multisite study of subcortical volumetric and lateralization alterations in schizophrenia, bipolar disorder, major depressive disorder, and autism spectrum disorder using T1-weighted images of 5604 subjects (3078 controls and 2526 patients). We demonstrated larger lateral ventricles volume in schizophrenia, bipolar disorder, and major depressive disorder, smaller hippocampus volume in schizophrenia and bipolar disorder, and schizophrenia-specific smaller amygdala, thalamus, and accumbens volumes and larger caudate, putamen, and pallidum volumes. In addition, we observed a leftward alteration of lateralization for pallidum volume specifically in schizophrenia. Moreover, as our main objective, we clustered the 5,604 subjects based on subcortical volumes, and explored whether data-driven clustering results can explain cognitive/social functioning in the subcohorts. We showed a four-biotype classification, namely extremely (Brain Biotype [BB] 1) and moderately smaller limbic regions (BB2), larger basal ganglia (BB3), and normal volumes (BB4), being associated with cognitive/social functioning. Specifically, BB1 and BB2-3 were associated with severe and mild cognitive/social impairment, respectively, while BB4 was characterized by normal cognitive/social functioning. Our results may lead to the future creation of novel biological data-driven psychiatric diagnostic criteria, which may be expected to be useful for prediction or therapeutic selection.

DOI： 10.1038/s41380-023-02141-9

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記述言語：日本語   出版者・発行元：(国研)国立精神・神経医療研究センター精神保健研究所  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

University students are in a phase during which they have various experiences typical in the academic environment and face situations that require adaptability and influence value formation. In the abnormal situation of the COVID-19 pandemic, university students' life rhythms, academic, interpersonal, and financial situations have changed drastically. In those situational cues, the value-based behavior of university students may have changed. Values provide purpose and direction for each action. Furthermore, values are situational goals that lead to specific real-time behavior. Therefore, this study aimed to examine whether there is a two-way influencing relationship between value-based behavior and scheduled activities of university students at two points in time (before the COVID-19 pandemic and during the COVID-19 pandemic). 417 university students answered a questionnaire at Times 1 and 2 (with a 1-year interval). We examined the relationship between value-based behavior and scheduled activities using a longitudinal cross-lagged model analysis. The findings of this study indicate that promoting value-based behaviors is positively associated with the frequency of value-based behaviors and scheduled activities even during anomalies such as the COVID-19 pandemic. Even in anomalous situations such as the COVID-19 pandemic, increasing value-based behaviors such as behavioral activation can improve the lives of university students. Future intervention studies should show whether behavioral activation is effective in decreasing depressive symptoms among university students even in abnormal situations such as the COVID-19 pandemic.

DOI： 10.1159/000530909

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Science and Business Media LLC  

Abstract

Although the identification of late adolescents with subthreshold depression (StD) may provide a basis for developing effective interventions that could lead to a reduction in the prevalence of StD and prevent the development of major depressive disorder, knowledge about the neural basis of StD remains limited. The purpose of this study was to develop a generalizable classifier for StD and to shed light on the underlying neural mechanisms of StD in late adolescents. Resting-state functional magnetic resonance imaging data of 91 individuals (30 StD subjects, 61 healthy controls) were included to build an StD classifier, and eight functional connections were selected by using the combination of two machine learning algorithms. We applied this biomarker to an independent cohort (n = 43) and confirmed that it showed generalization performance (area under the curve = 0.84/0.75 for the training/test datasets). Moreover, the most important functional connection was between the left and right pallidum, which may be related to clinically important dysfunctions in subjects with StD such as anhedonia and hyposensitivity to rewards. Investigation of whether modulation of the identified functional connections can be an effective treatment for StD may be an important topic of future research.

DOI： 10.1038/s41598-023-33077-3

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その他リンク： https://www.nature.com/articles/s41598-023-33077-3

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier BV  

DOI： 10.1016/j.jbtep.2023.101857

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記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：(一社)日本総合病院精神医学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

DOI： 10.1111/pcn.13542

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

BACKGROUND AND HYPOTHESIS: Dynamics of the distributed sets of functionally synchronized brain regions, known as large-scale networks, are essential for the emotional state and cognitive processes. However, few studies were performed to elucidate the aberrant dynamics across the large-scale networks across multiple psychiatric disorders. In this paper, we aimed to investigate dynamic aspects of the aberrancy of the causal connections among the large-scale networks of the multiple psychiatric disorders. STUDY DESIGN: We applied dynamic causal modeling (DCM) to the large-sample multi-site dataset with 739 participants from 4 imaging sites including 4 different groups, healthy controls, schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BD), to compare the causal relationships among the large-scale networks, including visual network, somatomotor network (SMN), dorsal attention network (DAN), salience network (SAN), limbic network (LIN), frontoparietal network, and default mode network. STUDY RESULTS: DCM showed that the decreased self-inhibitory connection of LIN was the common aberrant connection pattern across psychiatry disorders. Furthermore, increased causal connections from LIN to multiple networks, aberrant self-inhibitory connections of DAN and SMN, and increased self-inhibitory connection of SAN were disorder-specific patterns for SCZ, MDD, and BD, respectively. CONCLUSIONS: DCM revealed that LIN was the core abnormal network common to psychiatric disorders. Furthermore, DCM showed disorder-specific abnormal patterns of causal connections across the 7 networks. Our findings suggested that aberrant dynamics among the large-scale networks could be a key biomarker for these transdiagnostic psychiatric disorders.

DOI： 10.1093/schbul/sbad022

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

BACKGROUND: Recently, we developed a generalizable brain network marker for the diagnosis of major depressive disorder (MDD) across multiple imaging sites using resting-state functional magnetic resonance imaging. Here, we applied this brain network marker to newly acquired data to verify its test-retest reliability and anterograde generalization performance for new patients. METHODS: We tested the sensitivity and specificity of our brain network marker of MDD using data acquired from 43 new patients with MDD as well as new data from 33 healthy controls (HCs) who participated in our previous study. To examine the test-retest reliability of our brain network marker, we evaluated the intraclass correlation coefficients (ICCs) between the brain network marker-based classifier's output (probability of MDD) in two sets of HC data obtained at an interval of approximately 1 year. RESULTS: Test-retest correlation between the two sets of the classifier's output (probability of MDD) from HCs exhibited moderate reliability with an ICC of 0.45 (95 % confidence interval,0.13-0.68). The classifier distinguished patients with MDD and HCs with an accuracy of 69.7 % (sensitivity, 72.1 %; specificity, 66.7 %). LIMITATIONS: The data of patients with MDD in this study were cross-sectional, and the clinical significance of the marker, such as whether it is a state or trait marker of MDD and its association with treatment responsiveness, remains unclear. CONCLUSIONS: The results of this study reaffirmed the test-retest reliability and generalization performance of our brain network marker for the diagnosis of MDD.

DOI： 10.1016/j.jad.2023.01.087

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

COVID-19 has exposed university students to high-stress situations, and the percentage of individuals with depressive symptoms was high during the COVID-19 pandemic. Furthermore, subthreshold depression carries a risk for the subsequent development of major depressive disorder (MDD). During the COVID-19 pandemic, we examined whether differences exist between university students who deteriorated from subthreshold depression to MDD and those who remained stable or improved. Four hundred seventeen participants completed all the measures twice over a one-year interval. One hundred twenty-three participants met the criteria for subthreshold depression at Time 1. One year later, 42 participants no longer met the criteria for subthreshold depression, 68 participants maintained the criteria for subthreshold depression, and 13 participants met the criteria for MDD. We conducted two-way repeated measures ANOVA to examine the differences between those who deteriorated from subthreshold depression to MDD and those who did not. The study results suggest that avoidance behavior is associated with the development of MDD from subthreshold depression. Additionally, the study showed that experiencing isolation relates to MDD onset. Therefore, we should monitor avoidance behavior and isolation in pandemic conditions. Consequently, attention to avoidance behavior and isolation may be important; however, further research is required.

DOI： 10.3390/bs13010072

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記述言語：日本語   出版者・発行元：(一社)日本総合病院精神医学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

Trust attitude is a social personality trait linked with the estimation of others' trustworthiness. Trusting others, however, can have substantial negative effects on mental health, such as the development of depression. Despite significant progress in understanding the neurobiology of trust, whether the neuroanatomy of trust is linked with depression vulnerability remains unknown. To investigate a link between the neuroanatomy of trust and depression vulnerability, we assessed trust and depressive symptoms and employed neuroimaging to acquire brain structure data of healthy participants. A high depressive symptom score was used as an indicator of depression vulnerability. The neuroanatomical results observed with the healthy sample were validated in a sample of clinically diagnosed depressive patients. We found significantly higher depressive symptoms among low trusters than among high trusters. Neuroanatomically, low trusters and depressive patients showed similar volume reduction in brain regions implicated in social cognition, including the dorsolateral prefrontal cortex (DLPFC), dorsomedial PFC, posterior cingulate, precuneus, and angular gyrus. Furthermore, the reduced volume of the DLPFC and precuneus mediated the relationship between trust and depressive symptoms. These findings contribute to understanding social- and neural-markers of depression vulnerability and may inform the development of social interventions to prevent pathological depression.

DOI： 10.1038/s41598-022-20443-w

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

AIM: To establish treatment response biomarkers that reflect the pathophysiology of depression, it is important to use an integrated set of features. This study aimed to determine the relationship between regional brain activity at rest and blood metabolites related to treatment response to escitalopram to identify the characteristics of depression that respond to treatment. METHODS: Blood metabolite levels and resting-state brain activity were measured in patients with moderate to severe depression (n = 65) before and after 6-8 weeks of treatment with escitalopram, and these were compared between Responders and Nonresponders to treatment. We then examined the relationship between blood metabolites and brain activity related to treatment responsiveness in patients and healthy controls (n = 36). RESULTS: Thirty-two patients (49.2%) showed a clinical response (>50% reduction in the Hamilton Rating Scale for Depression score) and were classified as Responders, and the remaining 33 patients were classified as Nonresponders. The pretreatment fractional amplitude of low-frequency fluctuation (fALFF) value of the left dorsolateral prefrontal cortex (DLPFC) and plasma kynurenine levels were lower in Responders, and the rate of increase of both after treatment was correlated with an improvement in symptoms. Moreover, the fALFF value of the left DLPFC was significantly correlated with plasma kynurenine levels in pretreatment patients with depression and healthy controls. CONCLUSION: Decreased resting-state regional activity of the left DLPFC and decreased plasma kynurenine levels may predict treatment response to escitalopram, suggesting that it may be involved in the pathophysiology of major depressive disorder in response to escitalopram treatment.

DOI： 10.1111/pcn.13373

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その他リンク： https://onlinelibrary.wiley.com/doi/full-xml/10.1111/pcn.13373

記述言語：日本語   出版者・発行元：(国研)国立精神・神経医療研究センター精神保健研究所  

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Science and Business Media LLC  

DOI： 10.1038/s41598-022-06563-3

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その他リンク： https://www.nature.com/articles/s41598-022-06563-3

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier BV  

Attention function is thought to be important in chronic pain, with the pathology of chronic pain closely associated with cognitive-emotional components. However, there have been few neuroimaging studies of the relationship between attention function and chronic pain. We used the method of functional connectivity analysis for resting-state fMRI (rs-fMRI) data and the Attention Network Test-Revision (ANT-R) to clarify the attention-related pathology of chronic pain. We performed rs-fMRI and ANT-R on a group of 26 chronic pain (somatoform pain disorder) patients and 28 age-matched healthy controls. A significant group difference in validity effects, a component of ANT-R, emerged (F1,46 = 5.91, p = 0.019), and the chronic pain group exhibited slower reaction times. Decreased brain connectivity of the left insula and left frontal regions was confirmed in chronic pain patients (pFWE < 0.05), and connectivity was negatively correlated with validity effects (r = -0.29, permutation test p = 0.033). Further, decreased functional connectivity strength of the right insula and left temporal gyrus in the chronic pain group were confirmed (pFWE < 0.05). We conclude that poor control of attention function results from deficits of functional connectivity in the left insula and left frontal regions in chronic pain.

DOI： 10.1016/j.bandc.2021.105806

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Frontiers Media SA  

DOI： 10.3389/fpsyg.2021.566181

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掲載種別：研究論文（学術雑誌）  

DOI： 10.21203/rs.3.rs-911537/v1

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Science and Business Media LLC  

DOI： 10.1007/s41811-021-00108-8

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その他リンク： https://link.springer.com/article/10.1007/s41811-021-00108-8/fulltext.html

掲載種別：研究論文（学術雑誌）   出版者・発行元：科学評論社  

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掲載種別：研究論文（学術雑誌）  

DOI： 10.1111/pcn.13166

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その他リンク： https://onlinelibrary.wiley.com/doi/full-xml/10.1111/pcn.13166

掲載種別：研究論文（学術雑誌）  

DOI： 10.1002/brb3.1868

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その他リンク： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/brb3.1868

記述言語：日本語  

DOI： 10.15027/50080

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その他リンク： http://id.ndl.go.jp/bib/030660084

掲載種別：研究論文（学術雑誌）  

DOI： 10.3389/fnhum.2020.00165

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Frontiers Media {SA}  

DOI： 10.3389/fpsyg.2019.02536

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掲載種別：研究論文（学術雑誌）  

DOI： 10.3389/fnhum.2019.00289

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掲載種別：研究論文（学術雑誌）  

DOI： 10.2147/NDT.S172385

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DOI： 10.1192/bjo.2018.40

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掲載種別：研究論文（学術雑誌）  

DOI： 10.2147/NDT.S168077

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Cambridge University Press (CUP)  

DOI： 10.1017/S0033291717002598

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1097/wnr.0000000000000818

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掲載種別：研究論文（学術雑誌）  

DOI： 10.1038/s41598-017-03522-1

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その他リンク： http://www.nature.com/articles/s41598-017-03522-1

掲載種別：研究論文（学術雑誌）  

DOI： 10.1017/S0033291716002956

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掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jad.2016.06.046

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記述言語：日本語   出版者・発行元：(一社)日本認知・行動療法学会  

DOI： 10.24468/jjbt.42.2_237

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2016&ichushi_jid=J00454&link_issn=&doc_id=20160822010016&doc_link_id=%2Fdr4behav%2F2016%2F004202%2F017%2F0237-0246%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4behav%2F2016%2F004202%2F017%2F0237-0246%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：日本不安症学会  

本研究は，SAD患者の曖昧な場面の中性的・否定的解釈の関連の検討，および曖昧な場面の肯定的・中性的・否定的解釈がSAD症状の重症度に及ぼす影響について検討を行った。SAD患者50名を対象に，（1）Liebowitz Social Anxiety Scale（朝倉ら，2002），（2）曖昧な場面の解釈の質問紙について回答を求めた。相関分析の結果，曖昧な社会的場面の中性的解釈と否定的解釈の間に相関は認められず，曖昧な社会的場面の肯定的解釈と否定的解釈の間のみに負の相関が認められた（<i>r</i>=-.48, <i>p</i><.001）。重回帰分析の結果，曖昧な社会的場面の否定的解釈（β＝.34, <i>p</i><.05）のSAD症状の重症度への影響が有意であった。本研究の結果から，曖昧な場面の否定的解釈の低減にあたり，肯定的解釈の活性化の有効性が示唆された。

DOI： 10.14389/jsad.6.2_63

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記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：日本不安症学会  

重症社交不安障害(SAD)患者における拒絶に対する過敏性とうつ症状が社交不安症状に与える影響性について検討した。通院中のSAD患者62例を対象にアンケートを実施した。大うつ病の診断は35例であった。大うつ病の診断の有無について検討し、IPSMの関係破綻の不安、社会的自己像と真の自己像の不一致、合計点に有意差を認め、大うつ病の診断を有する群で得点が高かった。IPSMの各尺度間には、おおむね中程度から強い正の相関を認め、なかでもBDI-IIはLSASおよびIPSMのほぼ全ての下位因子および合計得点との間に強い正の相関を認めた。SAD症状の関係は擬相関で、うつ症状は拒絶に対する過敏性とSAD症状を媒介していると考えられた。

DOI： 10.14389/adr.6.7

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記述言語：日本語   出版者・発行元：一般社団法人 日本心身医学会  

本研究の目的は,他者からの拒絶に対する過敏性(以下,拒絶に対する過敏性)を測定する尺度であるInterpersonal Sensitivity Measure(IPSM;Boyce&Parker,1989の日本語版(J-IPSM)の信頼性および妥当性を検討し,本邦における拒絶に対する過敏性の因子構造について明らかにするとともに,非定型うつ病患者のうつ症状との関連を検討することであった.まず,尺度の信頼性・妥当性を検討するために大学生301名を対象に質問紙調査を行った.因子分析の結果,J-IPSMは「関係破綻の不安」,「他者を傷つける不安による非主張性」,「批判されることへの懸念」,「社会的自己像と真の自己像の不一致」,「他者評価追従」の5因子,27項目から構成され,内的整合性は高かった(α=0.78〜0.91).さらに,類似概念である「対人的傷つきやすさ尺度」(鈴木・小塩,2002)と強い正の相関が示され,J-IPSMは十分な信頼性・妥当性を備えた尺度であることが示された.次に,うつ症状との関連を検討するため,非定型うつ病患者を対象に質問紙調査を行った.その結果,J-IPSMにより測定される拒絶に対する過敏性とうつ症状との間に強い相関が認められた.

DOI： 10.15064/jjpm.54.5_422

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その他リンク： http://search.jamas.or.jp/link/ui/2014240618

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jad.2013.05.067

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記述言語：日本語   出版者・発行元：(一社)日本認知・行動療法学会  

DOI： 10.24468/jjbt.38.1_35

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2012&ichushi_jid=J00454&link_issn=&doc_id=20120229100004&doc_link_id=10.24468%2Fjjbt.38.1_35&url=https%3A%2F%2Fdoi.org%2F10.24468%2Fjjbt.38.1_35&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_2.gif

総ページ数：viii, 221p   記述言語：日本語

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記述言語：日本語   出版者・発行元：公益社団法人 日本心理学会  

DOI： 10.4992/pacjpa.89.0_442

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記述言語：日本語   出版者・発行元：公益社団法人 日本心理学会  

DOI： 10.4992/pacjpa.89.0_595

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担当区分：最終著者,　責任著者   記述言語：英語   掲載種別：研究発表ペーパー・要旨（国際会議）  

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担当区分：筆頭著者   記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）  

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掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）  

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記述言語：日本語   出版者・発行元：(一社)日本認知・行動療法学会  

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掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）  

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担当区分：筆頭著者   記述言語：日本語   掲載種別：会議報告等   出版者・発行元：日本慢性疼痛学会  

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記述言語：日本語   出版者・発行元：(国研)国立精神・神経医療研究センター精神保健研究所  

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記述言語：日本語   出版者・発行元：日本行動医学会  

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記述言語：日本語   出版者・発行元：日本認知療法・認知行動療法学会  

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記述言語：日本語   出版者・発行元：(公社)全国大学保健管理協会  

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記述言語：日本語   出版者・発行元：(一社)日本認知・行動療法学会  

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記述言語：日本語   出版者・発行元：(一社)日本認知・行動療法学会  

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記述言語：日本語   出版者・発行元：(一社)日本認知・行動療法学会  

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記述言語：日本語   出版者・発行元：(国研)国立精神・神経医療研究センター精神保健研究所  

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記述言語：日本語   出版者・発行元：日本生理心理学会  

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記述言語：日本語   出版者・発行元：(公社)日本精神神経学会  

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記述言語：日本語   出版者・発行元：(公社)日本精神神経学会  

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担当区分：筆頭著者   記述言語：日本語   出版者・発行元：産業医学振興財団  

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その他リンク： https://ndlsearch.ndl.go.jp/books/R000000004-I032400046

担当区分：筆頭著者   記述言語：日本語   出版者・発行元：(一社)日本産業精神保健学会  

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記述言語：日本語   出版者・発行元：広島医学会  

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記述言語：日本語   出版者・発行元：(一社)日本産業精神保健学会  

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記述言語：日本語   出版者・発行元：(公社)全国大学保健管理協会  

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記述言語：日本語   出版者・発行元：公益社団法人 日本生体医工学会  

新型コロナ感染症拡大は、従前から国家的社会課題であったうつ病や自殺などを増加させており、その脳科学に基づく治療法開発は喫緊の課題である。近年、fMRIなど脳機能解析研究により、うつ病の神経回路異常などの病態解明が進んでいる。演者らはうつ病患者のfMRI脳機能解析から、意欲低下に関連する背外側前頭前野(DLPFC)の機能低下、反芻症状（くよくよと反復考える）に関連する後部帯状回(PCC)の機能亢進を認め、これが抗うつ薬（SSRI）治療によって改善すること、およびDLPFC-PCCの機能的結合がうつ病のバイオマーカー候補となることを報告した。一方、DLPFCとPCCの機能が拮抗関係にあることに注目し、DLPFCを標的とするfMRIニューロフィードバック（NF)によりその活動を上昇させることで、PCC機能を抑制し、抗うつ作用があるかを調べるために探索的臨床試験を行った。その結果、抑うつ症状や反芻症状などが改善され、うつ病の非薬物治療法となりうることを示唆した。次に、より簡便で実用化可能なうつ病のNF治療開発のために、健常人を対象に、DLPFCを標的とするfNIRS-NFを行い、抑うつスコア（BDI)、反芻スコア（RRQ)の改善度、安全性およびNIRS-NF前後のfMRIによる脳機能変化を解析した。本セッションではこれらの研究成果を紹介するとともにfNIRSの将来展望について私見を述べる。

DOI： 10.11239/jsmbe.annual59.246

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記述言語：日本語   出版者・発行元：日本生物学的精神医学会  

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記述言語：日本語   出版者・発行元：(株)金剛出版  

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記述言語：日本語   出版者・発行元：(株)金剛出版  

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記述言語：日本語   出版者・発行元：(公社)全国大学保健管理協会  

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記述言語：日本語   出版者・発行元：日本認知療法学会  

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記述言語：日本語   出版者・発行元：(株)学樹書院  

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J-GLOBAL

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記述言語：日本語   出版者・発行元：(公社)全国大学保健管理協会  

J-GLOBAL

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記述言語：日本語   出版者・発行元：(公財)日本精神衛生会  

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記述言語：日本語   出版者・発行元：広島大学保健管理センター  

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J-GLOBAL

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記述言語：日本語   出版者・発行元：(株)中外医学社  

J-GLOBAL

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記述言語：日本語   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2018&ichushi_jid=J06546&link_issn=&doc_id=20181212310065&doc_link_id=10.24468%2Fjabctc.44.0_160&url=https%3A%2F%2Fdoi.org%2F10.24468%2Fjabctc.44.0_160&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

記述言語：日本語   出版者・発行元：(公社)日本心理学会  

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記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）  

J-GLOBAL

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掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：日本うつ病学会・日本認知療法・認知行動療法学会  

J-GLOBAL

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担当区分：筆頭著者   記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：日本うつ病学会・日本認知療法・認知行動療法学会  

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担当区分：筆頭著者   記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：日本うつ病学会・日本認知療法・認知行動療法学会  

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J-GLOBAL

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記述言語：日本語   掲載種別：記事・総説・解説・論説等（商業誌、新聞、ウェブメディア）   出版者・発行元：(有)科学評論社  

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記述言語：日本語   出版者・発行元：早稲田大学人間科学学術院  

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その他リンク： http://hdl.handle.net/2065/39387

記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2012&ichushi_jid=J05371&link_issn=&doc_id=20121129160175&doc_link_id=%2Fdr4beabs%2F2012%2F0038s1%2F164%2F0388-0389%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2012%2F0038s1%2F164%2F0388-0389%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2012&ichushi_jid=J05371&link_issn=&doc_id=20121129160145&doc_link_id=%2Fdr4beabs%2F2012%2F0038s1%2F134%2F0328-0329%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2012%2F0038s1%2F134%2F0328-0329%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

担当区分：筆頭著者   記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2012&ichushi_jid=J05371&link_issn=&doc_id=20121129160143&doc_link_id=%2Fdr4beabs%2F2012%2F0038s1%2F132%2F0324-0325%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2012%2F0038s1%2F132%2F0324-0325%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2012&ichushi_jid=J05371&link_issn=&doc_id=20121129160142&doc_link_id=%2Fdr4beabs%2F2012%2F0038s1%2F131%2F0322-0323%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2012%2F0038s1%2F131%2F0322-0323%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2011&ichushi_jid=J05371&link_issn=&doc_id=20120117240061&doc_link_id=%2Fdr4beabs%2F2011%2F0037s1%2F054%2F0188-0189%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2011%2F0037s1%2F054%2F0188-0189%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2011&ichushi_jid=J05371&link_issn=&doc_id=20120117240109&doc_link_id=%2Fdr4beabs%2F2011%2F0037s1%2F102%2F0286-0287%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2011%2F0037s1%2F102%2F0286-0287%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2011&ichushi_jid=J05371&link_issn=&doc_id=20120117240060&doc_link_id=%2Fdr4beabs%2F2011%2F0037s1%2F053%2F0186-0187%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2011%2F0037s1%2F053%2F0186-0187%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

担当区分：筆頭著者   記述言語：日本語   掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本認知・行動療法学会  

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2011&ichushi_jid=J05371&link_issn=&doc_id=20120117240206&doc_link_id=%2Fdr4beabs%2F2011%2F0037s1%2F198%2F0480-0481%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdr4beabs%2F2011%2F0037s1%2F198%2F0480-0481%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

開催年月日： 2023年12月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（指名）  

開催地：広島  

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開催年月日： 2023年10月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（公募）  

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開催年月日： 2022年11月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（指名）  

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開催年月日： 2022年9月 - 2022年10月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（公募）  

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開催年月日： 2022年3月

記述言語：日本語   会議種別：公開講演，セミナー，チュートリアル，講習，講義等  

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開催年月日： 2021年7月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（指名）  

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開催年月日： 2021年6月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（指名）  

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開催年月日： 2020年9月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（指名）  

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開催年月日： 2020年9月

記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（公募）  

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開催年月日： 2018年10月

記述言語：日本語  

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開催年月日： 2018年8月

記述言語：日本語  

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開催年月日： 2018年8月

記述言語：日本語  

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記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（指名）  

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記述言語：日本語   会議種別：シンポジウム・ワークショップ パネル（公募）  

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対象： 教育関係者,　行政機関

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対象： 高校生

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対象： 研究者,　社会人・一般

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