Updated on 2024/04/30

写真a

 
YOSHIZAWA Akiyasu
 
Organization
Academic Assembly Institute of Medicine and Dentistry Specially Appointed Associate Professor
Graduate School of Medical and Dental Sciences Specially Appointed Associate Professor
Title
Specially Appointed Associate Professor
Contact information
メールアドレス
External link

Degree

  • Ph.D. (Doctor of Science) ( 2007.5   Kyoto University )

Research Interests

  • mass spectrometry

  • bioinformatics (computational biology)

  • comparative genomics

  • database

Research Areas

  • Life Science / Biophysics  / biomembrane

  • Life Science / System genome science  / proteomics/metabolomics/comparative genomics

  • Informatics / Life, health and medical informatics  / bioinformatics

Research History (researchmap)

  • Niigata University   Medical AI Center, Graduate School of Medical and Dental Sciences   Project Associate Professor

    2023.5

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  • Toyama University of International Studies   Faculty of Contemporary Society   Project Researcher

    2022.4 - 2023.3

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  • Kyoto University   Graduate School of Pharmaceutical Sciences   Project Assistant Professor

    2018.4 - 2022.3

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  • Okayama University   Graduate School of Medicine , Dentistry and Pharmaceutical Sciences   Lecturer (part-time)

    2018.4 - 2020.3

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  • Kyoto University   Graduate School of Pharmaceutical Sciences   Program-Specific Researcher   Program-Specific Assisntant Professor

    2017.4 - 2018.3

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  • Kyoto University   Bioinformatics Center, Institute for Chemical Research   Program-Specific Researcher

    2015.6 - 2017.3

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  • (株)島津製作所   田中耕一記念質量分析研究所   研究員(嘱託)

    2014.10 - 2015.3

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  • (株)島津製作所   田中最先端研究所   研究員(嘱託)

    2014.4 - 2014.9

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  • (株)島津製作所   田中最先端研究所   内閣府FIRSTプログラム研究員(嘱託)

    2011.4 - 2014.3

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  • The University of Tokushima   The Institute for Enzyme Research   Researcher   Program-specific Assisntant Professor

    2009.1 - 2011.3

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  • National Institute of Advanced Industrial Science and Technology

    2007.4 - 2008.12

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  • Seisen College   Lecturer (part-time)

    1995.4 - 1997.3

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  • Kyoto Women's University   Faculty of Arts / Junior College Department / Liberal Arts Education   Lecturer (part-time)

    1992.10 - 2007.3

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  • Kyoto Women's University   Faculty of Arts   Lecturer (part-time)

    1991.10 - 1992.3

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Research History

  • Niigata University   Institute of Medicine and Dentistry, Academic Assembly   Specially Appointed Associate Professor

    2023.5

  • Niigata University   Graduate School of Medical and Dental Sciences   Specially Appointed Associate Professor

    2023.5

Education

  • Kyoto University   Graduate School of Science (Ph.D. course)   Department of Biological Science

    1999.4 - 2002.3

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    Country: Japan

    Notes: 編入学/研究指導認定(単位取得退学)

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  • Kyoto University   Graduate School of Science (Ph.D. course)   Department of Biophysics

    1989.4 - 1995.3

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    Country: Japan

    Notes: 進学/研究指導認定(単位取得退学)

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  • Kyoto University   Graduate School of Science (Master course)   Department of Biophysics

    1987.4 - 1989.3

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    Country: Japan

    Notes: 入学/修了

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  • Kyoto University   Faculty of Science

    1983.4 - 1987.3

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    Country: Japan

    Notes: 入学/卒業

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Professional Memberships

 

Papers

  • The jPOST Repository as a Public Data Repository for Shotgun Proteomics Invited Reviewed International journal

    Watanabe, Y, Yoshizawa, AC, Ishihama, Y, Okuda, S

    Methods in Molecular Biology   2259   309 - 322   2021.3

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    Language:English   Publishing type:Part of collection (book)   Publisher:Humana Press (Springer US)  

    DOI: 10.1007/978-1-0716-1178-4_20

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  • Aberrant splicing isoforms detected by full-length transcriptome sequencing as transcripts of potential neoantigens in non-small cell lung cancer Reviewed International journal

    Oka, M, Xu, L, Suzuki, T, Yoshikawa, T, Sakamoto, H, Uemura, H, Yoshizawa, AC, Suzuki, Y, Nakatsura, T, Ishihama, Y, Suzuki, A, Seki, M

    Genome Biology   22   9   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Science and Business Media LLC  

    <title>Abstract</title><sec>
    <title>Background</title>
    Long-read sequencing of full-length cDNAs enables the detection of structures of aberrant splicing isoforms in cancer cells. These isoforms are occasionally translated, presented by HLA molecules, and recognized as neoantigens. This study used a long-read sequencer (MinION) to construct a comprehensive catalog of aberrant splicing isoforms in non-small-cell lung cancers, by which novel isoforms and potential neoantigens are identified.


    </sec><sec>
    <title>Results</title>
    Full-length cDNA sequencing is performed using 22 cell lines, and a total of 2021 novel splicing isoforms are identified. The protein expression of some of these isoforms is then validated by proteome analysis. Ablations of a nonsense-mediated mRNA decay (NMD) factor, UPF1, and a splicing factor, SF3B1, are found to increase the proportion of aberrant transcripts. NetMHC evaluation of the binding affinities to each type of HLA molecule reveals that some of the isoforms potentially generate neoantigen candidates. We also identify aberrant splicing isoforms in seven non-small-cell lung cancer specimens. An enzyme-linked immune absorbent spot assay indicates that approximately half the peptide candidates have the potential to activate T cell responses through their interaction with HLA molecules. Finally, we estimate the number of isoforms in The Cancer Genome Atlas (TCGA) datasets by referring to the constructed catalog and found that disruption of NMD factors is significantly correlated with the number of splicing isoforms found in the TCGA-Lung Adenocarcinoma data collection.


    </sec><sec>
    <title>Conclusions</title>
    Our results indicate that long-read sequencing of full-length cDNAs is essential for the precise identification of aberrant transcript structures in cancer cells.


    </sec>

    DOI: 10.1186/s13059-020-02240-8

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    Other Link: http://link.springer.com/article/10.1186/s13059-020-02240-8/fulltext.html

  • Japan Computational Mass Spectrometry Meeting 2020 Activity Report Reviewed

    Yamamoto, H, Hayakawa, E, Tsugawa, H, Moriya, Y, Fukusaki, E, Goto, S, Hasunuma, T, Miura, N, Yoshizawa, AC

    Journal of Proteome Data and Methods   2   5   2020.12

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  • jPOST Tools (I): Utilities for Peak List Processing Reviewed

    Tabata, T, Yoshizawa, AC, Ishihama, Y

    Journal of Proteome Data and Methods   2   4   2020.12

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  • BioHackathon 2015: Semantics of data for life sciences and reproducible research Reviewed International coauthorship International journal

    Vos RA, Katayama T, Mishima H, Kawano S, KawashimaS, Kim J-D, Moriya Y, Tokimatsu T, Yamaguchi A, Yamamoto Y, Wu H, Amstutz P, Antezana E, Aoki NP, Arakawa K, Bolleman JT, Bolton E, Bonnal RJP, Bono H, Burger K, Chiba H, Cohen KB, Deutsch EW, Fernandez-Breis JT, Fu G, Fujisawa T, Fukushima A, Garcia A, Goto N, Groza T, Hercus C, Hoehndorf R, Itaya K, Juty N, Kawashima T, Kim J-H, Kinjo AR, Kotera M, Kozaki K, Kumagai S, Kushida T, Lutteke T, Matsubara M, Miyamoto J, Mohsen A, Mori H, Naito Y, Nakazato T, Nguyen-Xuan J, Nishida K, Nishida N, Nishide H, Ogishima S, Ohta T, Okuda S, Paten B, Perret J-L, Prathipati P, Prins P, Queralt-Rosinach N, Shinmachi D, Suzuki S, Tabata T, Takatsuki T, Taylor K, Thompson M, Uchiyama I, Vieira B, Wei C-H, Wilkinson M, Yamada I, Yamanaka R, Yoshitake K, Yoshizawa AC, Dumontier M, Kosaki K, Takagi T

    F1000Research   9   136   2020.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    <ns4:p>We report on the activities of the 2015 edition of the BioHackathon, an annual event that brings together researchers and developers from around the world to develop tools and technologies that promote the reusability of biological data. We discuss issues surrounding the representation, publication, integration, mining and reuse of biological data and metadata across a wide range of biomedical data types of relevance for the life sciences, including chemistry, genotypes and phenotypes, orthology and phylogeny, proteomics, genomics, glycomics, and metabolomics. We describe our progress to address ongoing challenges to the reusability and reproducibility of research results, and identify outstanding issues that continue to impede the progress of bioinformatics research. We share our perspective on the state of the art, continued challenges, and goals for future research and development for the life sciences Semantic Web.</ns4:p>

    DOI: 10.12688/f1000research.18236.1

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  • The jPOST environment: an integrated proteomics data repository and database. Reviewed

    Moriya Y, Kawano S, Okuda S, Watanabe Y, Matsumoto M, Takami T, Kobayashi D, Yamanouchi Y, Araki N, Yoshizawa AC, Tabata T, Iwasaki M, Sugiyama N, Tanaka S, Goto S, Ishihama Y

    Nucleic acids research   47 ( D1 )   D1218 - D1224   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/nar/gky899

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  • Meeting Report of the International Life Science Integration Workshop 2018 Reviewed International coauthorship International journal

    [No authors listed: Contributors] Yamada I, Akase S, Angata K, Aoki NP, Arita M, Campbell MP, Edwards N, Fujita A, Garcia L, Goto S, Henrissat B, Hosoda M, Ishihama Y, Kawasaki T, Kuoka T, Kurisu G, Lee S, Lisacek F, Mariethoz J, Narimatsu H, Neelamegham S, Okuda S, Ono T, Packer NH, Ranzinger R, Shinmachi D, Shiota M, Toukach P, Tsuchiya S, Watanabe Y, Yoshizawa AC, Aoki-Kinoshita KF

    Glycobiology   28 ( 8 )   552 - 555   2018.8

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    Language:English   Publishing type:Research paper (international conference proceedings)   Publisher:Oxford University Press (OUP)  

    DOI: 10.1093/glycob/cwy056

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  • jPOSTrepo: an international standard data repository for proteomes Reviewed

    Okuda S, Watanabe Y, Moriya Y, Kawano S, Yamamoto T, Matsumoto M, Takami T, Kobayashi D, Araki N, Yoshizawa AC, Tabata T, Sugiyama N, Goto S and Ishihama Y

    Nucleic acids research   45 ( D1 )   D1107 - D1111   2017.1

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:OXFORD UNIV PRESS  

    Major advancements have recently been made in mass spectrometry-based proteomics, yielding an increasing number of datasets from various proteomics projects worldwide. In order to facilitate the sharing and reuse of promising datasets, it is important to construct appropriate, high-quality public data repositories. jPOSTrepo (https://repository.jpostdb.org/) has successfully implemented several unique features, including high-speed file uploading, flexible file management and easy-to-use interfaces. This repository has been launched as a public repository containing various proteomic datasets and is available for researchers worldwide. In addition, our repository has joined the ProteomeXchange consortium, which includes the most popular public repositories such as PRIDE in Europe for MS/MS datasets and PASSEL for SRM datasets in the USA. Later MassIVE was introduced in the USA and accepted into the ProteomeXchange, as was our repository in July 2016, providing important datasets from Asia/Oceania. Accordingly, this repository thus contributes to a global alliance to share and store all datasets from a wide variety of proteomics experiments. Thus, the repository is expected to become a major repository, particularly for data collected in the Asia/Oceania region.

    DOI: 10.1093/nar/gkw1080

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  • Identification of human basic fetoprotein as glucose-6-phosphate isomerase by using N- and C-terminal sequence tags and terminal tag database. Reviewed

    Kuyama H, Yoshizawa AC, Nakajima C, Hosako M, Tanaka K

    Journal of pharmaceutical and biomedical analysis   112   116 - 125   2015.8

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpba.2015.04.032

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  • GlycanAnalysis Plug-in: a database search tool for N-glycan structures using mass spectrometry. Reviewed

    Morimoto K, Nishikaze T, Yoshizawa AC, Kajihara S, Aoshima K, Oda Y, Tanaka K

    Bioinformatics (Oxford, England)   31 ( 13 )   2217 - 2219   2015.7

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/bioinformatics/btv110

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  • Computational survey of sequence specificity for protein terminal tags covering nine organisms and its application to protein identification. Reviewed

    Yoshizawa AC, Fukuyama Y, Kajihara S, Kuyama H, Tanaka K

    Journal of proteome research   14 ( 2 )   756 - 767   2015.2

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/pr500793h

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  • A simple peak detection and label-free quantitation algorithm for chromatography-mass spectrometry Reviewed

    Aoshima K, Takahashi K, Ikawa M, Kimura T, Fukuda M, Tanaka S, Parry HE, Fujita Y, Yoshizawa AC, Utsunomiya S, Kajihara S, Tanaka K, Oda Y

    BMC Bioinformatics   15   376   2014.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:BIOMED CENTRAL LTD  

    Background: Label-free quantitation of mass spectrometric data is one of the simplest and least expensive methods for differential expression profiling of proteins and metabolites. The need for high accuracy and performance computational label-free quantitation methods is still high in the biomarker and drug discovery research field. However, recent most advanced types of LC-MS generate huge amounts of analytical data with high scan speed, high accuracy and resolution, which is often impossible to interpret manually. Moreover, there are still issues to be improved for recent label-free methods, such as how to reduce false positive/negatives of the candidate peaks, how to expand scalability and how to enhance and automate data processing. AB3D (A simple label-free quantitation algorithm for Biomarker Discovery in Diagnostics and Drug discovery using LC-MS) has addressed these issues and has the capability to perform label-free quantitation using MS1 for proteomics study.
    Results: We developed an algorithm called AB3D, a label free peak detection and quantitative algorithm using MS1 spectral data. To test our algorithm, practical applications of AB3D for LC-MS data sets were evaluated using 3 datasets. Comparisons were then carried out between widely used software tools such as MZmine 2, MSight, SuperHirn, OpenMS and our algorithm AB3D, using the same LC-MS datasets. All quantitative results were confirmed manually, and we found that AB3D could properly identify and quantify known peptides with fewer false positives and false negatives compared to four other existing software tools using either the standard peptide mixture or the real complex biological samples of Bartonella quintana (strain JK31). Moreover, AB3D showed the best reliability by comparing the variability between two technical replicates using a complex peptide mixture of HeLa and BSA samples. For performance, the AB3D algorithm is about 1.2-15 times faster than the four other existing software tools.
    Conclusions: AB3D is a simple and fast algorithm for label-free quantitation using MS1 mass spectrometry data for large scale LC-MS data analysis with higher true positive and reasonable false positive rates. Furthermore, AB3D demonstrated the best reproducibility and is about 1.2-15 times faster than those of existing 4 software tools.

    DOI: 10.1186/s12859-014-0376-0

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  • Computational Proteomics : Database-run Identification of Post-Translational Modification Invited

    Yoshizawa AC, Tabata T, Kimura T, Aoshima K, Fukuyama Y, Kajihara S, Kuyama H, Oda Y, Tanaka K

    128 ( 10 )   504 - 509   2014.10

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    Authorship:Lead author, Corresponding author   Language:Japanese   Publishing type:Research paper (bulletin of university, research institution)  

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  • Mass plus plus : A Visualization and Analysis Tool for Mass Spectrometry Reviewed

    Tanaka S, FujitaY, Parry HE, Yoshizawa AC, Morimoto K, Murase M, Yamada Y, Yao J, Utsunomiya S, Kajihara S, Fukuda M, Ikawa M, Tabata T, Takahashi K, Aoshima K, Nihei Y, Nishioka T, Oda Y, Tanaka K

    Journal of proteome research   13 ( 8 )   3846 - 3853   2014.8

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:AMER CHEMICAL SOC  

    We have developed Mass++, a plug-in style visualization and analysis tool for mass spectrometry. Its plug-in style enables users to customize it and to develop original functions. Mass++ has several kinds of plug-ins, including rich viewers and analysis methods for proteomics and metabolomics. Plug-ins for supporting vendors' raw data are currently available; hence, Mass++ can read several data formats. Mass++ is both a desktop tool and a software development platform. Original functions can be developed without editing the Mass++ source code. Here, we present this tool's capability to rapidly analyze MS data and develop functions by providing examples of label-free quantitation and implementing plug-ins or scripts. Mass++ is freely available at http://www.first-ms3d.jp/english/.

    DOI: 10.1021/pr500155z

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  • Integrated proteomics identified novel activation of dynein IC2-GR-COX-1 signaling in neurofibromatosis type I (NF1) disease model cells. Reviewed

    Hirayama M, Kobayashi D, Mizuguchi S, Morikawa T, Nagayama M, Midorikawa U, Wilson MM, Nambu AN, Yoshizawa AC, Kawano S, Araki N

    Molecular & cellular proteomics : MCP   12 ( 5 )   1377 - 1394   2013.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1074/mcp.M112.024802

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  • KEGG OC: a large-scale automatic construction of taxonomy-based ortholog clusters. Reviewed

    Nakaya A, Katayama T, Itoh M, Hiranuka K, Kawashima S, Moriya Y, Okuda S, Tanaka M, Tokimatsu T, Yamanishi Y, Yoshizawa AC, Kanehisa M, Goto S

    Nucleic acids research   41 ( Database issue )   D353 - 7   2013.1

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    DOI: 10.1093/nar/gks1239

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    Other Link: https://dblp.uni-trier.de/db/journals/nar/nar41.html#NakayaKIHKMOTTYYKG13

  • CIPRO 2.5: Ciona intestinalis protein database, a unique integrated repository of large-scale omics data, bioinformatic analyses and curated annotation, with user rating and reviewing functionality Reviewed

    Endo T, Ueno K, Yonezawa K, Mineta K, Hotta K, Satou Y, Yamada L, Ogasawara M, Takahashi H, Nakajima A, Nakachi M, Nomura M, Yaguchi J, Sasakura Y, Yamasaki C, Sera M, Yoshizawa AC, Imanishi T, Taniguchi H, and Inaba K

    Nucleic acids research   39 ( Database issue )   D807 - D814   2011.1

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:OXFORD UNIV PRESS  

    The Ciona intestinalis protein database (CIPRO) is an integrated protein database for the tunicate species C. intestinalis. The database is unique in two respects: first, because of its phylogenetic position, Ciona is suitable model for understanding vertebrate evolution; and second, the database includes original large-scale transcriptomic and proteomic data. Ciona intestinalis has also been a favorite of developmental biologists. Therefore, large amounts of data exist on its development and morphology, along with a recent genome sequence and gene expression data. The CIPRO database is aimed at collecting those published data as well as providing unique information from unpublished experimental data, such as 3D expression profiling, 2D-PAGE and mass spectrometry-based large-scale analyses at various developmental stages, curated annotation data and various bioinformatic data, to facilitate research in diverse areas, including developmental, comparative and evolutionary biology. For medical and evolutionary research, homologs in humans and major model organisms are intentionally included. The current database is based on a recently developed KH model containing 36 034 unique sequences, but for higher usability it covers 89 683 all known and predicted proteins from all gene models for this species. Of these sequences, more than 10 000 proteins have been manually annotated. Furthermore, to establish a community-supported protein database, these annotations are open to evaluation by users through the CIPRO website. CIPRO 2.5 is freely accessible at http://cipro.ibio.jp/2.5.

    DOI: 10.1093/nar/gkq1144

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  • ODB: a database for operon organizations, 2011 update Reviewed

    Okuda S, Yoshizawa AC

    Nucleic acids research   39 ( Database issue )   D552 - D555   2011.1

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    ODB (Operon DataBase) aims to collect data of all known and conserved operons in completely sequenced genomes. Three newly updated features of this database have been added as follows: (i) Data from included operons were updated. The genome-wide analysis of transcription and transcriptional units has become popular recently and ODB successfully integrates these high-throughput operon data, including genome-wide transcriptional units of five prokaryotes and two eukaryotes. The current version of our database contains information from about 10 000 known operons in more than 50 genomes, and more than 400 000 conserved operons obtained from more than 1000 bacterial genomes. (ii) ODB proposes the idea of reference operons as a new operon prediction tool. A reference operon, a set of possible orthologous genes that organize operons, is defined by clustering all known operons. A large number of known operons, including the recently added genome-wide analysis of operons, allowed us to define more reliable reference operons. (iii) ODB also provides new graphical interfaces. One is for comparative analyses of operon structures in multiple genomes. The other is for visualization of possible operons in multiple genomes obtained from the reference operons. The 2011 updated version of ODB is now available at http://operondb.jp/.

    DOI: 10.1093/nar/gkq1090

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  • Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism. Reviewed

    Okamura-Ikeda K, Hosaka H, Maita N, Fujiwara K, Yoshizawa AC, Nakagawa A, Taniguchi H

    The Journal of biological chemistry   285 ( 24 )   18684 - 18692   2010.6

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    DOI: 10.1074/jbc.M110.110718

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  • An age-related homeostasis mechanism is essential for spontaneous amelioration of hemophilia B Leyden. Reviewed

    Kurachi S, Huo JS, Ameri A, Zhang K, Yoshizawa AC, Kurachi K

    Proceedings of the National Academy of Sciences of the United States of America   106 ( 19 )   7921 - 7926   2009.5

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    DOI: 10.1073/pnas.0902191106

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  • Comprehensive analysis of glycosyltransferases in eukaryotic genomes for structural and functional characterization of glycans. Reviewed

    Hashimoto K, Tokimatsu T, Kawano S, Yoshizawa AC, Okuda S, Goto S, Kanehisa M

    Carbohydrate research   344 ( 7 )   881 - 887   2009.5

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    DOI: 10.1016/j.carres.2009.03.001

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  • The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes. Reviewed

    Hashimoto K, Yoshizawa AC, Okuda S, Kuma K, Goto S, Kanehisa M

    Journal of lipid research   49 ( 1 )   183 - 191   2008.1

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    DOI: 10.1194/jlr.M700377-JLR200

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  • KAAS: an automatic genome annotation and pathway reconstruction server. Reviewed

    Moriya Y, Itoh M, Okuda S, Yoshizawa AC, Kanehisa M

    Nucleic acids research   35 ( Web Server issue )   W182 - 5   2007.7

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    DOI: 10.1093/nar/gkm321

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  • Extracting sequence motifs and the phylogenetic features of SNARE-dependent membrane traffic. Reviewed

    Yoshizawa AC, Kawashima S, Okuda S, Fujita M, Itoh M, Moriya Y, Hattori M, Kanehisa M

    Traffic (Copenhagen, Denmark)   7 ( 8 )   1104 - 1118   2006.8

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1600-0854.2006.00451.x

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  • The repertoire of desaturases for unsaturated fatty acid synthesis in 397 genomes. Reviewed

    Hashimoto K, Yoshizawa AC, Saito K, Yamada T, Kanehisa M

    Genome informatics. International Conference on Genome Informatics   17 ( 1 )   173 - 183   2006

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    Language:English   Publishing type:Research paper (international conference proceedings)  

    DOI: 10.11234/gi1990.17.173

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  • A Standpoint of Education of Informatics in the Liberal Arts [Reprint]

    Yoshizawa, AC

    21 ( 3 )   328 - 333   2004

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    Language:Japanese   Publishing type:Part of collection (book)  

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  • A Standpoint of Education of Informatics in the Liberal Arts

    Yoshizawa, AC

    Proceedings of Department of Education, Kyoto Women's University   39   131 - 142   1999

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  • Problems on Education of Computer Science for Female Undergraduate Students (I)

    Yoshizawa, AC

    Proceedings of Department of Education, Kyoto Women's University   38   78 - 87   1998

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  • Problems on Education of Computer Science for Female Undergraduate Students (II) ; On the Internet Literacy

    Yoshizawa, AC

    Proceedings of Department of Education, Kyoto Women's University   38   88 - 93   1998

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  • Development of a Streak-Camera-Based Time-Resolved Microscope Fluorimeter and Its Application to Studies of Membrane Fusion in Single Cells Reviewed

    Kusumi A, Tsuji A, Murata M, Sako Y, Yoshizawa AC, Kagiwada S, Hayakawa T, and Ohnishi S

    Biochemistry   30   6517 - 6527   1991.7

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    A time-resolved microscope fluorimeter based on a synchroscan streak camera and a fast pulsed laser system has been developed to measure the fluorescence lifetime decay under the fluorescence microscope. This system allows one to measure the nanosecond fluorescence lifetimes of fluorophores in a small spot (0.8-6.3 μm diameter) in single cultured cells under a fluorescence microscope, while the cells are being viewed under a high-power objective lens. A signal acquisition time between a second and a minute was usually sufficient to obtain fluorescence decay curves with good quality for 103-10sfluorophores localized in 1 μm2domain. A signal-to-noise ratio better than 30 was obtained for =30 000 fluorescein-labeled band 3 molecules in a 2 μm2region in a single human erythrocyte ghost after signal accumulation for 30 s. The measured lifetimes for a variety of fluorescent probes attached to proteins in solution and lipids in liposomes showed a good agreement with those measured in a cuvette under standard conditions by time-correlated single photon counting. With the development of this instrument, microscope fluorimetry has become a practical, straightforward, quantitative technique for investigation of molecular processes in single cells in culture. Time-resolved microscope fluorimetry has been applied to observe fusion of liposomes in vitro and that of endosomes in single cells by monitoring resonance energy transfer. Inspection of individual liposomes and endosomes revealed the extent of fusion for each vesicle. Since the use of time-resolved microscope fluorimetry eliminates the need for subcellular fractionation or the complex correction procedures in steady-state microfluorimetry, it greatly simplifies the assay for endosome fusion in vivo. The results showed that extensive fusion of sequentially formed endosomes takes place all over the cell matrix in cultured cells. This suggests that extensive fusion with incoming endosomes takes place in many endosomal compartments, possibly sorting organelles, or that the early endosomes fuse with the preexisting network of tubular cisternae of the endosomal compartment at many points in the network. It is concluded that time-resolved microscope fluorimetry is a powerful noninvasive technique for studies of in situ biochemistry and biophysics using cells and tissues. © 1991, American Chemical Society. All rights reserved.

    DOI: 10.1021/bi00240a024

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Books

  • Encyclopedia of genetics : origin of inheritance and diversity Reviewed

    Genetics Society of Japan( Role: Contributor ,  9-19 Proteome Analysis)

    Maruzen Publishing  2022.1  ( ISBN:9784621306604

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    Total pages:xvii, 668p   Language:Japanese Book type:Dictionary, encyclopedia

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  • よくわかるバイオインフォマティクス入門 (KS生命科学専門書) Reviewed

    岩部 直之, 川端 猛, 浜田 道昭, 門田 幸二, 須山 幹太, 光山 統泰, 黒川 顕, 森 宙史, 東 光一, 吉沢 明康, 片山 俊明, 藤 博幸( Role: Contributor)

    講談社  2018.11  ( ISBN:4065138213

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    Total pages:208   Language:Japanese Book type:Scholarly book

    ASIN

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  • 老年医学 update 2009-10 Reviewed

    日本老年医学会雑誌編集委員会( Role: Contributor ,  III 老年医学の展望,老化・老年病と年齢軸生命工学)

    メジカルビュー  2009.6  ( ISBN:9784758304801

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  • ゲノミクス・プロテオミクスの新展開 : 生物情報の解析と応用

    今中 忠行, 加藤 郁之進( Role: Contributor ,  第3編バイオインフォマティクス,第1章データベース,第6節 代謝データベース)

    エヌ・ティー・エス  2004.4  ( ISBN:4860430492

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  • 事後ペプチドシーケンスタグの利用によるタンパク質同定の精度向上

    吉沢 明康, 田畑 剛, 岩崎 未央, 杉山 直幸, Kaell Lukas, 石濱 泰

    電気泳動   63 ( Suppl. )   245 - 245   2019.7

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    Language:Japanese   Publisher:日本電気泳動学会  

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  • メタプロテオミクスのためのデータ解析ワークフロー開発

    上村駿人, 伊藤麻里子, 吉沢明康, 杉山直幸, 石濱泰

    日本薬学会年会要旨集(CD-ROM)   138年会 ( 2 )   240 - 240   2018.3

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  • Construction of proteome database

    吉沢 明康

    京都大学化学研究所スーパーコンピュータシステム研究成果報告書   2016   27 - 27   2017.3

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    Language:Japanese   Publishing type:Internal/External technical report, pre-print, etc.   Publisher:京都大学化学研究所  

    平成28年度 京都大学化学研究所 スーパーコンピュータシステム 利用報告書

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  • jPOST:同定結果のFDR改善を目指す再解析プロトコルの開発

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 杉山直幸, 田中聡, 五斗進, 石濱泰

    日本生化学会大会(Web)   90th   ROMBUNNO.3P‐0172 (WEB ONLY) - 0172]   2017

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  • jPOST:プロテオーム統合データベースプロジェクト

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    日本生化学会大会(Web)   90th   ROMBUNNO.3P‐0171 (WEB ONLY) - 0171]   2017

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  • jPOST:プロテオームデータベースの開発

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    日本生化学会大会(Web)   90th   ROMBUNNO.3P‐0173 (WEB ONLY) - 0173]   2017

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  • Which Database to Use? —Confusions and Puzzles in Database Search and Sequence Analysis— Invited Reviewed

    Yoshizawa Akiyasu C

    Proteome Letters   1 ( 2 )   63 - 80   2016.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本プロテオーム学会  

    &lt;p&gt;For mass spectrometry based-proteomics studies, computational analyses of obtained data are indispensable. However, the analysis methodologies and software for mass spectrometry and/or proteomics are currently still under development and many problems thus remain unfixed; consequently, researchers, especially experimental scientists, often suffer from technical issues and popular misinterpretations. Based on these problems, we describe in this review the computational processes for protein identification for proteomics beginners, especially the algorithms of database search and related basic issues: the comparison of &lt;i&gt;de novo&lt;/i&gt; sequencing method and database search method, the effects of PTM detection on the search results, an overview of life science databases, and tips and cautions for their application to database searches.&lt;/p&gt;

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  • Construction of proteome database

    吉沢 明康

    京都大学化学研究所スーパーコンピュータシステム研究成果報告書   2015   23 - 23   2016.3

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    平成27年度 京都大学化学研究所 スーパーコンピュータシステム 利用報告書

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  • jPOST:プロテオーム解析ワークフローの標準化

    守屋勇樹, 河野信, 奥田修二郎, 山本格, 松本雅記, 小林大樹, 荒木令江, 吉沢明康, 五斗進, 田畑剛, 杉山直幸, 石濱泰

    日本生化学会大会(Web)   88th   3P0417 (WEB ONLY) - [3P0417]   2015.12

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  • Mass++、MassBankを用いた脂質同定システムの構築

    田中 聡, 吉沢 明康, 草野 麻衣子, 藤田 雄一郎, 福田 充, 宇都宮 眞一, 梶原 茂樹, 田畑 剛, 高橋 健太郎, 青島 健, 小田 吉哉, 二瓶 義人, 西岡 孝明, 田中 耕一

    JSBMS Letters   38 ( Suppl. )   95 - 95   2013.8

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  • Crystal structure of T-H protein complex of the glycine cleavage system International journal

    Okamura-Ikeda, K, Hosaka, H, Maita, N, Fujiwara, K, Yoshizawa, A.C, Nakagawa, A, Taniguchi, H

    Acta Crystallographica Section A Foundations of Crystallography   67 ( a1 )   C434 - C435   2011.8

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    Publisher:International Union of Crystallography (IUCr)  

    DOI: 10.1107/s0108767311089082

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  • CIPRO 2.5: Ciona intestinalis Protein integrated database with large-scale omics data, bioinformatic analyses and curated annotation, with ability for user rating and comments International journal

    Endo, T, Ueno, K, Yonezawa, K, Mineta, K, Hotta, K, Satou, Y, Yamada, L, Ogasawara, M, Takahashi, H, Nakajima, A, Nakachi, M, Nomura, M, Yaguchi, J, Konno, A, Sasakura, Y, Yoshizawa, A.C, Taniguchi, H, Yamasaki, C, Sera, M, Imanishi, T, Inaba, K

    Nature Precedings, Biocuration 2010   2011.1

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    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:Springer Science and Business Media LLC  

    Abstract

    CIPRO database is an integrated protein database for a tunicate species Ciona intestinalis that belongs to the Urochordata. Although the CIPRO database deals with proteomic and transcriptomic data of a single species, the animal is considered unique in the evolutionary tree, representing a possible origin of the vertebrates and is a good model for understanding chordate evolution, including that of humans. Furthermore, C. intestinalis has been one of the favorites of developmental biologists; there exists a huge amount of accumulated knowledge on its development and morphology, in addition to the recent genome sequence and gene expression data. The CIPRO database is aimed at not only collecting published data, but also presenting unique information, including the unpublished transcriptomic and proteomic data and human curated annotation, for the use by researchers in broad research fields of biology and bioinformatics.

    DOI: 10.1038/npre.2010.5435.1

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    Other Link: https://www.nature.com/articles/npre.2010.5435.1

  • CIPRO 2.5: Ciona intestinalis Protein Database - a unique integrated repository of large-scale omics data, bioinformatic analyses, and curated annotation, with ability for user rating and comments International journal

    Endo, T, Ueno, K, Yonezawa, K, Mineta, K, Hotta, K, Satou, Y, Yamada, L, Ogasawara, M, Takahashi, H, Nakajima, A, Nakachi, M, Nomura, M, Yaguchi, J, Konno, A, Sasakura, Y, Yoshizawa, A.C, Taniguchi, H, Yamasaki, C, Sera, M, Imanishi, T, Inaba, K

    Genome Biology   11 ( S1 )   2010.10

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    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:Springer Science and Business Media LLC  

    DOI: 10.1186/gb-2010-11-s1-p11

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    Other Link: http://link.springer.com/article/10.1186/gb-2010-11-s1-p11/fulltext.html

  • KEGG OC:全生物種ゲノムにおけるオーソログ遺伝子のバリエーションと高速検索技術

    片山俊明, 伊藤真純, 奥田修二郎, 川島秀一, 田中道廣, 時松敏明, 中谷明弘, 平糠和志, 守屋勇樹, 山西芳裕, 吉沢明康, 金久實

    生化学   80 ( 抄録CD )   4T9-4 - 4   2008.11

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  • Aging and gerotological diseases in relation to age-related homeostasis and age dimension technology Reviewed

    KURACHI Kotoku, KURACHI Sumiko, HAMADA Toshiyuki, SUENAGA Emi, YOSHIZAWA Akiyasu C

    Japanese journal of geriatrics   45 ( 2 )   126 - 131   2008.3

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本老年医学会  

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  • 遺伝子エレメントASE結合核蛋白質の同定 年齢軸恒常性分子機構の確立に向けて

    倉地 須美子, 笠間 絵美, 田中 拓, 吉沢 明康, 倉地 幸徳

    日本血栓止血学会誌   18 ( 5 )   460 - 460   2007.10

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  • Analysis of Tissue Specific Expression Patterns of Isozymes International journal

    Takarabe, M, Tsuchida, A, Fujita, M, Okuda, S, Yoshizawa, AC, Yamada, T, Itoh, M, Goto, S, Kanehisa, M

    Genome Informatics, GIW 2006 Poster Abstracts   17   2006.12

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  • The Analysis of the Eukaryotic Intracellular Vesicular Transport

    吉沢明康

    京都大学化学研究所スーパーコンピューターラボラトリー 平成17年度 研究成果報告書   96 - 97   2006.3

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  • The Analysis of the Intracellular Vesicular Transport Pathways

    吉沢明康

    京都大学化学研究所スーパーコンピューターラボラトリー 平成16年度 研究成果報告書   65 - 66   2005.3

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  • Functional Classification of Coiled-Coil Proteins in Multiple Genomes International journal

    Yoshizawa, AC, Okuda, S, Moriya, Y, Itoh, M, Katayama, T, Kawano, S, Okamoto, S, Kawashima, S, Kanehisa, M

    Genome Informatics, GIW 2004 Poster Abstracts   15   2004.12

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  • Automatic generation of KEGG OC (Ortholog Cluster) and its assignment to draft genomes International journal

    Moriya, Y, Katayama, T, Nakaya, A, Itoh, M, Yoshizawa, AC, Okuda, S, Kanehisa, M

    Genome Informatics, GIW 2004 Poster Abstracts   15   2004.12

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  • Functional Categorization of Multiple Genomes using KEGG OC in the Genome Indices International journal

    Okuda, S, Yoshizawa, AC, Moriya, Y, Itoh, M, Katayama, T, Goto, S, Kanehisa, M

    Genome Informatics, GIW 2004 Poster Abstracts   15   2004.12

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  • Analysis of the bacterial sequences recognized by RNA-binding proteins and compounds International journal

    Muto, A, Yoshizawa, AC, Okuda, S, Itoh, M, Hattori, M, Kanehisa, M

    Genome Informatics, GIW 2004 Poster Abstracts   15   2004.12

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  • Integration of Biological Features of Multiple Genomes - The Construction of "Genome Indices" database - International journal

    Okuda, S, Yoshizawa, AC, Moriya, Y, Itoh, M, Goto, S, Kanehisa, M

    Genome Informatics, IBSB 2004 Poster Abstracts   15   2004.5

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  • Prediction and Comparison of Coiled-Coil Proteins in Multiple Genomes International journal

    Yoshizawa, AC, Okuda, S, Itoh, M, Katayama, S, Kawashima, S, Kanehisa, M

    Genome Informatics, IBSB 2004 Poster Abstracts   15   2004.5

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  • The Analysis of the Proteins Participated in the Intracellular Vesicular Transport

    吉沢明康

    京都大学化学研究所スーパーコンピューターラボラトリー 平成15年度 研究成果報告書   73 - 74   2004.3

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  • Extraction of Organism Groups from Whole Genome Comparisons International journal

    Yamanishi, Y, Yoshizawa, AC, Itoh, M, Katayama, T, Kanehisa, M

    Genome Informatics   14   438 - 439   2003.12

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  • The Construction of a Database for Ubiquitin Signaling Cascade International journal

    Sakiyama, T, Kawashima, S, Yoshizawa, AC, Kanehisa, M

    Genome Informatics   14   653 - 654   2003.12

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  • Analysis of Domain Combinations in Eukaryotic Genomes International journal

    Itoh, M, Yoshizawa, AC, Okuda, S, Goto, S, Kanehisa, M

    Genome Informatics   14   434 - 435   2003.12

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  • Comprehensive Survey of Intracellular Transport System-Related Proteins in Complete Genomes and Draft Genomes International journal

    Yoshizawa, AC, Itoh, M, Okuda, S, Limviphuvadh, V, Sakiyama, T, Kawashima, S, Kanehisa, M

    Genome Informatics   14   436 - 437   2003.12

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  • Metabolic pathway reconstruction for malaria parasite Plasmodium falciparum International journal

    Limviphuvadh, V, Okuno, Y, Katayama, T, Goto, S, Yoshizawa, AC, Kanehisa, M

    Genome Informatics   14   368 - 369   2003.12

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  • The Analysis of the Intracellular Vesicular Transport System

    吉沢明康

    京都大学化学研究所スーパーコンピューターラボラトリー 平成14年度 研究成果報告書   66 - 68   2003.3

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  • Comparative analysis of Rab GTPases and SNAREs in eukaryotic genomes International journal

    Yoshizawa, AC, Kawashima, S, Kanehisa, M

    Genome Informatics   13   404 - 405   2002.12

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  • Indirect relations in yeast protein interactome International journal

    Nakaya, A, Yoshizawa, AC, Goto, S, Kanehisa, M

    Genome Informatics   13   328 - 329   2002.12

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  • The Analysis of the Intracellular Vesicular Transport.

    吉沢明康

    京都大学化学研究所スーパーコンピューターラボラトリー 平成13年度 研究成果報告書   80 - 82   2002.3

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  • Extraction of related genes in the vesicular transport by simultaneous comparison of two-hybrid and microarray data International journal

    Yoshizawa, AC, Nakaya, A, Goto, S, Kanehisa, M

    Genome Informatics   12   243 - 244   2001.12

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  • The construction of a database on the intracellular vesicular transport International journal

    Yoshizawa, AC, Kawashima, S, Kanehisa, M

    Genome Informatics   11   276 - 277   2000.12

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  • Development of a Time-Resolved Microfluorimeter with a Synchroscan Streak Camera and Its Application to Studies of Cell Membranes International journal

    Kusumi, A, Tsuji, A, Murata, M, Sako, Y, Yoshizawa, AC, Hayakawa, T, Ohnishi, S

    Time-Resolved Laser Spectroscopy in Biochemistry (Proceedings of SPIE)   1988.5

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Presentations

  • jPOST & JPDM: a database for proteomics and a journal for data articles

    Akiyasu C. Yoshizawa, Daiki Kobayashi, Yuki Moriya, Atsushi Hatano, Tomoyo Takami, Masaki Matsumoto, Norie Araki, Tsuyoshi Tabata, Mio Iwasaki, Naoyuki Sugiyama, Yoshio Kodera, Satoshi Tanaka, Susumu Goto, Shin Kawano, Shujiro Okuda, Yasushi Ishihama

    The 46th Annual Meeting of the Molecular Biology Society of Japan  2023.12  The Molecular Biology Society of Japan

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    Event date: 2023.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Kobe   Country:Japan  

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  • Current Development Status of MB-POST, a Metabolome Data Repository

    Yoshizawa, A.C.

    2023.10 

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    Event date: 2023.10

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  • From mass information to sequence information - how far can we trust? Invited

    Yoshizawa, AC

    JCompMS 7th Open Workshop ONLINE "Deep Reading of Mass Spectrometry Omics Data"  2022.4 

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    Event date: 2022.4

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • A Novel Method of Peptide Ion Peak-picking for Mass Spectrometry Based on Deep Learning Invited

    Yoshizawa, A.C.

    17ty Annual Meeting of Japan Society of Clinical Proteogenomics  2021.5  Japan Society of Clinical Proteogenomics

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    Event date: 2021.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Online   Country:Japan  

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  • Protein identification by massspectrogram hierarchical clustering in shotgun-proteomics

    Hikita, T., Kibe, K., Yoshizawa, A.C, Tabata, T., Yoshii, K., Ishihama, Y.

    The 2nd Workshop on Biological Molecule Analysis  2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Online   Country:Japan  

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  • Protein identification by massspectrogram hierarchical clustering in shotgun-proteomics

    Hikita, T., Kibe, K., Yoshizawa, A.C, Tabata, T., Yoshii, K., Ishihama, Y.

    The 141st Annual Meeting of the Pharmaceutical Society of Japan  2021.3  Pharmaceutical Society of Japan

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Online   Country:Japan  

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  • World of Computational Mass Spectrometry: Where Does It Come From?What Is It? Where Is It Going to? Invited

    Yoshizawa, A.C.

    nformatics in Biology, Medicine and Pharmacology 2020 (IIBMP: JSBi Congress 2020)  2020.9  Japanese Society for Bioinformatics

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    Event date: 2020.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:ONLINE  

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  • An extension of Mass++ ver.4, a data viewer, for proteome analysis International conference

    Tanaka, S., Murase, M., Kato, M., Tabata, T., Kusano, M., Kawano, S., Goto, S., Ishihama, Y., Yoshizawa, A.C.

    ASMS 2020 Reboot (68th ASMS (American Society for Mass Spectrometry) Conference on Mass Spectrometry and Allied Topics)  2020.6  ASMS

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    Event date: 2020.6

    Language:English   Presentation type:Poster presentation  

    Venue:Online   Country:United States  

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  • jPOST統合環境の機能深化と連携基盤強化

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 松本雅記, 高見知代, 小林大樹, 山ノ内祥訓, 荒木令江, 吉沢明康, 田畑剛, 岩崎未央, 杉山直幸, 田中聡, 五斗進, 石濱泰

    トーゴーの日シンポジウム2019  2019.10  バイオサイエンスデータベースセンター (NBDC)

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    Venue:東京  

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  • Mass++ ver.4 - An open-source MS data viewer with enhanced basic functions and easy implementation of external software International conference

    Tanaka, S, Murase, M, Kato, M, Yamamoto, H, Tabata, T, Kusano, M, Kawano, S, Goto, S, Ishihama, Y, Yoshizawa, AC

    ASMS 2023 (70th ASMS (American Society for Mass Spectrometry) Conference on Mass Spectrometry and Allied Topics)  2023.6 

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  • Temporal Analysis of Proteome and Phosphoproteomeof the SARS-CoV-2 Infected Cell International conference

    Watanabe, Y, Muramoto, Y, Oda, Y, Ogata, K, Yoshizawa, A, Sugiyama, N, Noda, T, Toyoshima, F, Ishihama, Y

    6th International Symposium of Kyoto Biomolecular Mass Spectrometry Society/International Symposium on Mass Spectrometry Imaging 2023 Kyoto  2023.1 

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  • Mass++ ver.4 -MS data viewer meets online databases- International conference

    Tanaka, S, Murase, M, Kato, M, Yamamoto, H, Tabata, T, Kusano, M, Kawano, S, Goto, S, Ishihama, Y, Yoshizawa, AC

    Human Proteome Organization World Congress (HUPO2022)  2022.12 

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  • jPOST:「コミュニティ・ベース論文調査」によるメタデータキュレーションの加速

    吉沢明康, 守屋勇樹, 小林大樹, 張智翔, 奥田修二郎, 田畑剛, 河野信, 幡野敦, 高見知代, 松本雅記, 山ノ内祥訓, 荒木令江, 岩崎未央, 杉山直幸, 福島敦史, 田中聡, 五斗進, 石濱 泰

    トーゴーの日シンポジウム2022  2022.10 

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  • There're five mysteries about jPOST Invited

    Yoshizawa, AC

    JPrOS2022 Conference (20th JHUPO Congress)  2022.8 

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  • Development of Mixed MS/MS Spectrogram Decomposition for DIA Proteomics

    Machida, K, Uemura, K, Tabata, T, Ogata, K, Yoshizawa, AC, Yoshii, K, Tanaka, T, Ishihama, Y

    The 3rd Workshop on Biological Molecule Analysis  2022.3 

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  • Development of Mixed MS/MS Spectrogram Decomposition for DIA Proteomics

    Machida, K, Uemura, K, Tabata, T, Ogata, K, Yoshizawa, AC, Yoshii, K, Tanaka, T, Ishihama, Y

    The 142nd Annual Meeting of the Pharmaceutical Society of Japan  2022.3 

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  • jPOSTrepoメタデータのSDRF化

    有馬佳奈美, 岡本瑠璃, 小林大樹, 吉沢明康, 河野信

    トーゴーの日シンポジウム2021  2021.10 

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  • jPOSTdb: COVID-19データベースの構築

    吉沢明康, 守屋勇樹, 小林大樹, 張智翔, 奥田修二郎, 田畑剛, 河野信, 幡野敦, 高見知代, 松本雅記, 山ノ内祥訓, 荒木令江, 岩崎未央, 杉山直幸, 福島敦史, 田中聡, 五斗進, 石濱 泰

    トーゴーの日シンポジウム2021  2021.10 

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  • jPOSTリポジトリの機能強化

    渡辺由, 奥田修二郎, 守屋勇樹, 河野信, 松本雅記, 高見知代, 小林大樹, 幡野敦, 山ノ内祥訓, 荒木令江, 吉沢明康, 田畑剛, 岩崎未央, 杉山直幸, 田中聡, 石濱泰

    トーゴーの日シンポジウム2020  2020.10  バイオサイエンスデータベースセンター

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    Venue:オンライン  

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  • トリプシン消化ペプチドの衝突誘起解離スペクトルの予測とショットガンプロテオミクスへの応用

    橘本哲志, 吉沢明康, 吉井和佳, 石濱泰

    日本薬学会第140年会(大会開催中止、要旨web公開を以て発表成立と規定)  2020.3  日本薬学会

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    COVID-19対応のため、web要旨公開を以て発表成立扱い

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  • Statistical Joint Protein and Peptide Quantification Based on Hierarchical Clustering of Mass Spectrograms International conference

    Kibe, K., Yoshizawa, A.C., Tabata,T., Yoshii, K., Ishihama, Y.

    4th International Symposium of the Kyoto Biomolecular Mass Spectrometry Society (KBMSS)  2020.2  KBMSS

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    Venue:Kyoto  

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  • Database Development for Proteomics Invited

    Yoshizawa, A.C.

    2019.12  Kumamoto Univ. Medical School

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    Venue:Kumamoto  

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  • マススペクトログラムの階層クラスタリングに基づくタンパク質同定

    木部航希, 吉沢明康, 田畑剛, 吉井和佳, 石濱泰

    第42回日本分子生物学会年会  2019.12  日本分子生物学会

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    Venue:福岡市  

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  • 配列タグを用いたタンパク質配列超高速検索システムの開発

    吉沢明康, 内藤雄樹, 早川英介, 五斗進, 石濱泰

    第42回日本分子生物学会年会  2019.12  日本分子生物学会

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    Venue:福岡市  

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  • 深層学習を用いたペプチド由来質量分析イオンピークの検出法の開発

    守屋勇樹, 田畑剛, 岩崎未央, 河野信, 五斗進, 石濱泰, 瀧川一学, 吉沢明康

    第42回日本分子生物学会年会  2019.12  日本分子生物学会

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    Venue:福岡市  

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  • プロテオームデータベースjPOSTの挑戦

    石濱泰, jPOST project

    トーゴーの日シンポジウム2019  2019.10 

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  • Peptide end sequence information in HCD spectra for protein identification International conference

    Yoshizawa, A.C, Tabata, T, Sugiyama, N, Ishihama, Y

    18th Human Proteome Organization World Congress (HUPO2019)  2019.9 

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  • Mass++ ver.4: an open-source, simple and extensible MS data viewer International conference

    Tanaka, S, Murase, M, Kato, M, Tabata, T, Kusano, M, Kawano, S, Goto, S, Ishihama, Y, Yoshizawa, A

    18th Human Proteome Organization World Congress (HUPO2019)  2019.9 

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  • Network analysis of proteogenomics data in lung cancer cell lines International conference

    Watanabe Y, Ling Y, Uemura H, Yoshizawa, A.C, Ishihama Y, Okuda S

    18th Human Proteome Organization World Congress (HUPO2019)  2019.9 

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  • UniScore, a universal measure for annotated peptide product ion spectra International conference

    Tabata, T, Yoshizawa, A.C, Sugiyama, N, Ishihama, Y

    18th Human Proteome Organization World Congress (HUPO2019)  2019.9 

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  • プロテオゲノミクスのための解析プラットフォーム開発

    上村駿人, 吉沢明康, 杉山直幸, 奥田修二郎, 石濱泰

    日本分析化学会 第68年会  2019.9 

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  • Development of Annotation Support Tool with SPARQL and Sequence Cluster

    YOSHIZAWA Akiyasu C

    IIBMP2019  2019.9 

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  • 階層クラスタリングを用いたLC/MS/MSマススペクトログラムのタンパク質同定

    木部航希, 吉沢明康, 田畑剛, 吉井和佳, 石濱泰

    PPF2019 第17回次世代を担う若手のためのフィジカル・ファーマフォーラム  2019.9 

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  • Improvement of protein identification accuracy using posterior peptide sequence tags

    Yoshizawa A.C, Tabata, T, Iwasaki, M, Sugiyama, N, Käll, L, Ishihama, Y

    2019.7  Japanse Proteomics Society

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    Venue:Miyazaki  

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  • Claque and Decoy -Discriminating real results from false results for computational proteomics- Invited

    YOSHIZAWA Akiyasu C

    Pre Meeting of 3rd Hackathon for Computational Mass Spectrometry  2019.7  Computational Mass Spectrometry SIG (JSBi)

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    Venue:Ibusuki, Kagoshima, Japan  

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  • The sushi proteome project towards unveiling dietary metaproteomes without genomic information International conference

    Nishida, H, Yoshizawa, A.C, Tabata, T, Sugiyama, N, Okuda, S, Ishihama, Y

    67th ASMS Conference on Mass Spectrometry and Allied Topics  2019.6  ASMS (American Society for Mass Spectrometry)

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    Venue:Atlanta, GA  

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  • High Accuracy Protein Identification Using Posterior Peptide Sequence Tags International coauthorship

    Tabata, T, Yoshizawa, A, Iwasaki, M, Sugiyama, N, Käll, L, Ishihama, Y

    The 67th Annual Conference on Mass Spectrometry, Japan  2019.5  The Mass Spectrometry Society of Japan

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    Venue:Tsukuba  

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  • A Novel Peptide Ion Peak Picking Method Based on Deep Learning

    Moriya, y, Tabata, T, Iwasaki, M, Kawano, S, Goto, S, Ishihama, Y. Takigawa, I, Yoshizawa, A

    The 67th Annual Conference on Mass Spectrometry, Japan  2019.5  The Mass Spectrometry Society of Japan

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    Venue:Tsukuba  

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  • Development of a metaproteomics platform for microbe analysis International conference

    Sakamoto, Y, Ito, M, Kashiwagi, Y, Nozaki,T, Murakami, S, Yoshizawa, A.C, Sugiyama, N, Ishihama, Y

    3rd KBMSS Symposium  2019.2  Kyoto Biomolecular Mass Spectrometry Society

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    Venue:Kyoto  

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  • Metaproteomics of Mouse Tissues and Feces (3P-0081)

    2018.11 

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  • Developement of functional and interactive database for proteomics

    2018.11 

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  • Metaproteomics of Mouse Tissues and Feces (1PW1-02-3)

    2018.11 

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  • jPOSTプロジェクトが提供するプロテオミクスデータとその解析ツール Invited

    五斗進, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 松本雅記, 高見知代, 小林大樹, 山ノ内祥訓, 荒木令江, 吉沢 明康, 田畑剛, 岩崎未央, 杉山直幸, 田中聡, 石濱泰

    第41回日本分子生物学会年会  2018.11  日本分子生物学会

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  • Analysis of proteome mass spectrometry data Invited

    Akiyasu C. Yoshizawa

    Clinical Mass Spectrometer Platform The 3rd training course on mass spectrometry  2018.11 

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  • 機械学習に基づくペプチド由来イオンピークの新規検出手法

    守屋勇樹, 田畑剛, 岩崎未央, 河野信, 五斗進, 石濱泰, 瀧川一学, 吉沢明康

    第21回情報論的学習理論ワークショップ (IBIS2018)  2018.11  電子情報通信学会 情報論的学習理論と機械学習研究会

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  • Development of jPOST environment

    2018.10 

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  • Mass Spectrometry meets Genome Information Invited

    Akiyasu C. Yoshizawa

    Informatics in Biology, Medicine and Pharmacology 2018 (IIBMP)  2018.9 

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  • Protein Identification by Hierarchical Clustering of LC/MS/MS Mass Spectrogram

    Koki Kibe, Akiyasu C. Yoshizawa, Tsuyoshi Tabata. KazuyoshiYoshii, Yasushi Ishihama

    IIBMP2018  2018.9 

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  • Mass++ ver.4: an open-source, quick and simple data viewer International conference

    Satoshi Tanaka, Masaki Murase, Tsuyoshi Takahashi, Masaki Kato, Maiko Kusano, Shin Kawano, Akiyasu C. Yoshizawa, Susumu Goto, Yasushi Ishihama

    66th ASMS Conference on Mass Spectrometry and Allied Topics (ASMS2018)  2018.6 

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  • Utilizing peptide sequence tags for controlling false discovery rates in database search International conference

    Akiyasu C. Yoshizawa, Tsuyoshi Tabata, Mio Iwasaki, Naoyuki Sugiyama, Yasushi Ishihama

    66th ASMS Conference on Mass Spectrometry and Allied Topics (ASMS2018)  2018.6 

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  • プロテオミクスは環境化学に貢献できるか? Invited

    吉沢 明康

    第27回環境化学討論会  2018.5  日本環境化学会・質量分析インフォマティクス研究会

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  • Application of Non-negative Matrix Factorization in Mass Spectrometry-Based Shotgun Proteomics (4P-40) International conference

    Taechawattananant, P, Yoshizawa, AC, Yoshii, K, Ishihama, Y

    MSP2018  2018.5 

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  • Application of Non-negative Matrix Factorization in Mass Spectrometry-Based Shotgun Proteomics (4C-O2-P-1605) International conference

    Pasrawin Taechawattananant, Akiyasu C. Yoshizawa, Kazuyoshi Yoshii, Yasushi Ishihama

    MSP2018  2018.5 

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  • Metadata Curation for fully utilizing raw MS data in jPOST repository International conference

    Kobayashi, D, Araki, N, Okuda, S, Watanabe, Y, Moriya, Y, Kawano, S, Yamamoto, T, Matsumoto, T, Takami, T, Yoshizawa, A.C, Tabata, T, Iwasaki, M, Sugiyama, N, Tanaka, S, Goto, S, Ishihama, Y

    MSP2018  2018.5 

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  • Accuracy of Peptide Isotope Distribution in Mass Spectra (2P-43) International conference

    Kibe, K, Yoshizawa, AC, Tabata, T, Yoshii, K, Ishihama, Y

    MSP2018  2018.5 

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  • Accuracy of Peptide Isotope Distribution in Mass Spectra (2B-O3-M-1805) International conference

    Kibe, K, Yoshizawa, AC, Tabata, T, Yoshii, K, Ishihama, Y

    MSP2018  2018.5 

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  • Non-negative Matrix Factorization for Mass Spectrometry-Based Protein Identification International conference

    Pasrawin Taechawattananant, Akiyasu C. Yoshizawa, Kazuyoshi Yoshii, Yasushi Ishihama

    RECOMB2018  2018.4 

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  • メタプロテオミクスのためのデータ解析ワークフロー開発

    上村駿人, 伊藤麻里子, 吉沢明康, 杉山直幸, 石濱泰

    2018.3 

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  • Posting more precisive pictures of proteomes Invited International conference

    YOSHIZAWA Akiyasu C

    International Life Science Integration Workshop  2018.3 

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  • L1-Regularized Nonnegative Matrix Factorization for Mass Spectrometry-Based Shotgun Proteomics International conference

    Pasrawin, T, Yoshizawa, A.C, Yoshii, K, Ishihama, Y

    第2回京都生体質量分析研究会 (KBMSS) シンポジウム  2018.2  京都生体質量分析研究会 (KBMSS)

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  • jPOST:Development of proteome database

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    2017.12 

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  • jPOST: Development of reanalysis protocol toward control of false discovery rate in peptide identification

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 杉山直幸, 田中聡, 五斗進, 石濱泰

    2017.12 

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  • jPOST: Integrated database for proteomes

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    2017.12 

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  • jPOST: メタデータのキュレーション

    小林大樹, 荒木令江, 奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    トーゴーの日シンポジウム2017  2017.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • jPOST: タンパク質発現絶対量sliceの開発

    松本雅記, 高見知代, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    トーゴーの日シンポジウム2017  2017.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • jPOST データベースの開発

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    トーゴーの日シンポジウム2017  2017.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • jPOST: 再解析プロトコルによる同定結果の質的向上

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 杉山直幸, 田中聡, 五斗進, 石濱泰

    トーゴーの日シンポジウム2017  2017.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • jPOST:プロテオーム統合データベースプロジェクト

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    トーゴーの日シンポジウム2017  2017.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • Controlling FalseDiscovery Rates on Large-scale Proteome Datasets in jPOST International conference

    Ishihama, Y, Yoshizawa, A, Tabata, T, Moriya, Y, Kawano, S, Okuda, S, Watanabe, Y, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Sugiyama, N, Tanaka, S, Goto, S

    16th Human Proteome Organization World Congress 2017 (HUPO2017)  2017.9 

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  • jPOST provides a global public data repository for a wide variety of proteomics experiments International conference

    Watanabe, Y, Okuda, S, Moriya, Y, Kawano,S, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Yoshizawa, A.C, Tabata, T, Sugiyama, N, Tanaka, S, Goto, S, Ishihama, Y

    16th Human Proteome Organization World Congress  2017.9 

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  • Reducing false positive identifications for proteome datasets accumulated in jPOST repository International conference

    Yoshizawa, A.C, Tabata, T, Moriya, Y, Kawano, S, Okuda, S, Watanabe, Y, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Sugiyama, N, Tanaka, S, Goto, S, Ishihama, Y

    16th Human Proteome Organization World Congress  2017.9 

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  • Development of integrated proteomics database: jPOST International conference

    Moriya, Y, Kawano,S, Okuda, S, Watanabe, Y, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Yoshizawa, A.C, Tabata, T, Sugiyama, N, Tanaka, S, Goto, S, Ishihama, Y

    16th Human Proteome Organization World Congress  2017.9 

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  • From Mass to Sequence, From Results to Database Invited

    YOSHIZAWA Akiyasu C

    JASIS2017 Conferenc  2017.9 

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  • プロテオーム統合データベース jPOST:質量分析データ・リポジトリ(2P-16)

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    日本プロテオーム学会2017年大会(JHUPO第15回大会)  2017.7 

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  • jPOST: プロテオーム統合データベースの開発(2P-18)

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    2017.7 

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  • プロテオーム統合データベースjPOST:質量分析データ・リポジトリ (2S-2-2)

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石濱泰

    2017.7 

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  • jPOST再解析プロトコル:偽陽性と偽陰性の同時減少を目指す Invited

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 杉山直幸, 田中聡, 五斗進, 石濱泰

    2017.7 

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  • jPOST:プロテオーム統合データベースの開発 (2S-2-4)

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 田中聡, 五斗進, 石澤泰

    2017.7 

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  • 同定結果はどこまで信頼できるか―データベース検索の落とし穴― Invited

    吉沢明康

    2017.7 

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  • プロテオミクスデータ解析2「Computational ProteomicsからProteome Informaticsへ」/演習 Invited

    YOSHIZAWA, Akiyasu C

    The 44th Biological Mass Spectrometry Conference  2017.7 

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  • Controlling false discovery rate in accumulated public proteome dataset International conference

    Yoshizawa, A.C, Tabata, T, Moriya, Y, Kawano, S, Okuda, S, Watanabe, Y, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Sugiyama, N, Tanaka, S, Goto, S, Ishihama, Y

    65th ASMS(American Society for Mass Spectrometry) Conference on Mass Spectrometry and Allied Topics  2017.6 

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  • データベース検索エンジンを用いたタンパク質同定における特異性向上

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 杉山直幸, 田中聡, 五斗進, 石濱泰

    2017.5 

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  • Challenges in standardization of database search: development of the jPOST repository and the re-analysis protocol Invited International conference

    YOSHIZAWA, AC

    1st International Symposium of KBMSS (Kyoto Biomolecular Mass Spectrometry Society)  2017.2 

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  • プロテオーム統合データベースjPOST:再解析プロトコルの開発

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 杉山直幸, 五斗進, 石濱泰

    第39回日本分子生物学会年会  2016.12  日本分子生物学会

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    Venue:横浜  

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  • プロテオーム統合データベースjPOST:質量分析データ・リポジトリの公開(2P-0039)

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知世, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 五斗進, 石濱泰

    第39回日本分子生物学会年会  2016.12 

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  • プロテオーム統合データベースjPOST:質量分析データ・リポジトリの公開(1PS7-4)

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 五斗進, 石濱泰

    第39回日本分子生物学会年会  2016.11 

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  • jPOST:プロテオームデータベースプロジェクト

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知世, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 五斗進, 石濱泰

    第39回日本分子生物学会年会  2016.11 

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  • jPOST: 再解析考え中です

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 杉山直幸, 五斗進, 石濱泰

    トーゴーの日シンポジウム2016  2016.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • jPOST: リポジトリ始めました

    奥田修二郎, 渡辺由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 五斗進, 石濱泰

    トーゴーの日シンポジウム2016  2016.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • jPOST: 今こんな感じです

    守屋勇樹, 河野信, 奥田修二郎, 渡辺由, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 五斗進, 石濱泰

    トーゴーの日シンポジウム2016  2016.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • 実はタンパク質は測定していない ~ プロテオミクスと質量分析法 ~ Invited

    吉沢 明康

    第5回生命医薬情報学連合大会(IIBMP2016)  2016.9  日本バイオインフォマティクス学会

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  • jPOST: repository and re-analysis protocol

    Moriya, Y, Yoshizawa, AC, Tabata, T, Kawano, S, Watanabe, Y, Okuda, S, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Sugiyama, N, Goto, S, Ishihama, Y

    IIBMP2016  2016.9 

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  • jPOST for Asia and Oceania: Repository Opened (P03-01) International conference

    Okuda, S, Watanabe, Y, Moriya, Y, Kawano, S, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Yoshizawa, AC, Tabata, T, Sugiyama, N, Goto, S, Ishihama, Y

    The 8th Asia Oceania Human Proteome Organization (AOHUPO) Congress  2016.9  AOHUPO

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  • A Novel Data Integration Tool iPEACH Identified the Specific Molecular Networks of Cancer Stem Cells International conference

    Yamasaki, Y, Nambu,A, Silsirivanit, A, Kobayashi, D, Yoshizawa, A, Kawano, S, Araki, N

    The 8th Asia Oceania Human Proteome Organization (AOHUPO) Congress  2016.9 

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  • jPOST for Asia and Oceania: Re-analysis Protocol International conference

    Yoshizawa, A.C, Tabata, T, Moriya, Y, Kawano, S, Okuda, S, Watanabe, Y, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Sugiyama, N, Goto, S, Ishihama, Y

    The 8th Asia Oceania Human Proteome Organization (AOHUPO) Congress  2016.9 

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  • jPOST for Asia and Oceania: Repository Opened (S03-01) International conference

    Okuda, S, Watanabe, Y, Moriya, Y, Kawano, S, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Yoshizawa, A.C, Tabata, T, Sugiyama, N, Goto, S, Ishihama, Y

    The 8th Asia Oceania Human Proteome Organization (AOHUPO) Congress  2016.9 

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  • jPOST for Asia and Oceania: Current status in 2016 International conference

    Moriya, Y, Kawano, S, Watanabe, Y, Okuda, S, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Yoshizawa, A.C, Goto, S, Tabata, T, Sugiyama, N, Ishihama, Y

    The 8th Asia Oceania Human Proteome Organization (AOHUPO) Congress  2016.9 

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  • jPOST: Re-analysis Protocol International conference

    Yoshizawa, A.C, Tabata, T, Moriya, Y, Kawano, S, Okuda, S, Watanabe, Y, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Sugiyama, N, Goto, S, Ishihama, Y

    15th Human Proteome Organization World Congress (HUPO2016)  2016.9 

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  • Analysis of the specific molecular networks of cancer stem cells using a novel data integration tool iPEACH International conference

    Yamasaki, Y, Nambu,A, Silsirivanit, A, Kobayashi, D, Yoshizawa, A, Kawano, S, Araki, N

    15th Human Proteome Organization World Congress (HUPO2016)  2016.9 

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  • jPOST: repository opened International conference

    Okuda, S, Watanabe, Y, Moriya, Y, Kawano, S, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Yoshizawa, A, Tabata, T, Sugiyama, N, Goto, S, Ishihama, Y

    15th Human Proteome Organization World Congress (HUPO2016)  2016.9 

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  • jPOST: Current status in 2016 International conference

    Moriya, Y, Kawano, S, Watanabe, Y, Okuda, S, Yamamoto, T, Matsumoto, M, Takami, T, Kobayashi, D, Araki, N, Yoshizawa, A.C, Goto, S, Tabata, T, Sugiyama, N, Ishihama, Y

    15th Human Proteome Organization World Congress (HUPO2016)  2016.9 

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  • プロテオーム統合データベースjPOSTの開発 Invited

    五斗進, 奥田修二郎, 渡邉由, 守屋勇樹, 河野信, 山本格, 松本雅記, 高見知代, 小林大樹, 荒木令江, 吉沢明康, 田畑剛, 杉山直幸, 石濱泰

    日本プロテオーム学会大会  2016.7 

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  • プロテオーム統合データベースjPOST:再解析プロトコルの開発

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 渡邉由, 山本格, 松本雅記, 高見知世, 小林大樹, 荒木令江, 杉山直幸, 五斗進, 石濱泰

    日本プロテオーム学会大会  2016.7 

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  • ポストだけれど葉書じゃない、タンパクだけど淡泊じゃない Invited

    吉沢 明康

    第2回バイオインフォマティクスアゴラ  2016.7 

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  • オープンソース版Mass++:ピーク検出機能の拡充

    田中聡, 太田悠葵, 村瀬雅樹, 津元裕樹, 草野麻衣子, 吉沢明康, 三浦ゆり, 川崎ナナ, 五斗進

    2016.5 

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  • 質量スペクトルはデータベース検索“グレーゾーン”を明瞭化するか

    吉沢明康, 田畑剛, 守屋勇樹, 河野信, 奥田修二郎, 山本格, 松本雅記, 小林大樹, 荒木令江, 杉山直幸, 五斗進, 石濱泰

    質量分析総合討論会  2016.5 

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  • jPOST:プロテオーム解析ワークフローの標準化

    守屋勇樹, 河野信, 奥田修二郎, 山本格, 松本雅記, 小林大樹, 荒木令江, 吉沢明康, 五斗進, 田畑剛, 杉山直幸, 石濱泰

    2015.12 

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  • オープンソース版Mass++によるオミックス解析

    2015.12 

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  • jPOST: Development of a high-quality proteome database

    Moriya, Y, Kawano, S, Okuda, S, Yamamoto, T, Matsumoto, M, Kobayashi, D, Araki, N, Yoshizawa, AC, Goto, S, Tabata, T, Sugiyama, N, Ishihama, Y

    第4回生命医薬情報学連合大会(IIBMP2015)  2015.10  日本バイオインフォマティクス学会

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  • Open-sourced Mass++ for Mass Spectrometric Data Analysis

    Murase, M, Tanaka, S, Yoshizawa, AC, Goto, S

    2015.10 

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  • Search space reduction by utilizing known modification information for proteomic database search

    Yoshizawa, AC, Tabata, T, Moriya, Y, Kawano, S, Goto, S, Ishihama, Y

    第4回生命医薬情報学連合大会(IIBMP2015)  2015.10  日本バイオインフォマティクス学会

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  • タンパク質同定とデータベース

    吉沢 明康

    jPOST Workshop: Computational Proteomics  2015.10 

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  • jPOST (Japan Proteome Standard Repository/Database):プロテオーム・データの標準化と統合

    守屋勇樹, 河野信, 奥田修二郎, 山本格, 松本雅記, 小林大樹, 荒木令江, 吉沢明康, 五斗進, 田畑剛, 杉山直幸, 石濱泰

    トーゴーの日シンポジウム2015  2015.10  JST バイオサイエンスデータベースセンター (NBDC)

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  • jPOST: Development of Japan ProteOme STandard repository/database International conference

    Kawano, S, Moriya, Y, Okuda, S, Yamamoto, T, Matsumoto, M, Kobayashi, D, Araki, N, Yoshizawa, A.C, Tabata, T, Sugiyama, N, Goto, S, Ishihama, Y

    14th Human Proteome Organization World Congress (HUPO2015)  2015.9 

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  • 融合プロテオミクスの統合ソフトウェア iPEACH によるグリオーマ幹細胞の維持と分化に関わるネットワーク解析

    山崎義宗, 河野信, 吉沢明康, 南部晶子, 水口惣平, 小林大樹, 長山慈, 永井美奈子, Silsirivanit Atit, 佛淵尚人, 荒木令江

    日本プロテオーム学会2015年会(JHUPO第13回大会)  2015.7  日本プロテオーム学会

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  • 日本発の高品質プロテオームデータベース:jPOST

    守屋勇樹, 河野信, 奥田修二郎, 山本格, 松本雅記, 小林大樹, 荒木令江, 吉沢明康, 五斗進, 田畑剛, 杉山直幸, 石濱泰

    日本プロテオーム学会2015年会(JHUPO第13回大会)  2015.7  日本プロテオーム学会

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  • オープンソース版Mass++とプロテオーム解析

    田中 聡, 村瀬雅樹, 吉沢明康, 五斗 進

    日本プロテオーム学会2015年会(JHUPO第13回大会)  2015.7  日本プロテオーム学会

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  • どのデータベースを使うか ~データベース検索と配列解析・誤解と難題~ Invited

    吉沢 明康

    日本プロテオーム学会2015年会  2015.7  日本プロテオーム学会

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  • データベースを使ったタンパク質同定 Invited

    吉沢 明康

    JHUPO2015プロテオミクストレーニングコース  2015.7 

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  • オープンソース版Mass++

    田中聡, 田中聡, 吉沢明康, 吉沢明康, 五斗進

    質量分析総合討論会講演要旨集  2015.6 

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  • 質量分析ソフトウェアMass++を用いたN型糖鎖負イオンMS/MSスペクトルの解析

    森本健太郎, 西風隆司, 吉沢明康, 梶原茂樹, 青島健, 小田吉哉, 田中耕一

    質量分析総合討論会講演要旨集  2014.5 

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  • Mass++:同定機能と翻訳後修飾文献DBとの連携

    田中聡, 吉沢明康, 田畑剛, 草野麻衣子, 青島健, 宇都宮眞一, 梶原茂樹, 小田吉哉, 田中耕一

    質量分析総合討論会講演要旨集  2014.5 

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  • Cross-organism comparison of protein terminal sequences and development of terminal sequence database

    Yoshizawa, AC, Fukuyama, Y, Kajihara,S, Kuyama, H, Tanaka, K

    日本分子生物学会年会  2013.12 

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  • 計算プロテオミクス:データベースを利用したタンパク質翻訳後修飾の同定 Invited

    吉沢明康, 田畑剛, 木村剛之, 青島健, 福山裕子, 梶原茂樹, 九山浩樹, 小田吉哉, 田中耕一

    第694回新潟医学会シンポジウム「生命システムの理解に向けたバイオインフォーマティクス」  2013.11  新潟医学会

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  • Mass++, MassBank を用いた脂質同定システムの構築

    田中聡, 吉沢明康, 草野麻衣子, 藤田雄一郎, 福田充, 宇都宮眞一, 梶原茂樹, 田畑剛, 高橋健太郎, 青島健, 小田吉哉, 二瓶義人, 西岡孝明, 田中耕一

    日本医用マススペクトル学会第38回年会  2013.9 

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  • 融合プロテオミクスによる神経線維腫症1型(NF1)病態モデル細胞内活性化シグナルDynein IC2‐GR‐COX‐1の同定

    小林大樹, 平山未央, 水口惣平, 森川崇, 長山慈, 緑川宇一, WILSON‐MORIFUJI Masayo, 南部(新堀)晶子, 吉沢明康, 河野信, 荒木令江

    日本生化学会大会(Web)  2013.9 

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  • Mass++:質量分析データの一括解析

    田中聡, 藤田雄一郎, 吉沢明康, 福田充, 宇都宮眞一, 梶原茂樹, 青島健, 小田吉哉, 田中耕一

    質量分析総合討論会講演要旨集  2013.9 

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  • 質量分析用データ解析ソフトウェアMass++とマススペクトルデータベースMassBank連携プラグインの開発

    青島健, 福田充, 井川幹之, 高橋健太郎, 木村剛之, 梶原茂樹, 宇都宮眞一, 田中聡, 吉沢明康, 田中耕一, 池田奨, 二瓶義人, 西岡孝明, 小田吉哉

    質量分析総合討論会講演要旨集  2013.9 

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  • ユーザーによる処理の追加可能なproteome解析プラットフォームJobRequestと,それを利用したタンパク質同定ツールProteoAnalysis

    田畑剛, 吉沢明康, 山本昇, 青島健, 小田吉哉, 梶原茂樹, 田中耕一

    質量分析総合討論会講演要旨集  2013.9 

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  • ヒトタンパク質末端配列データベースの構築と末端配列の一意性の推定

    吉沢明康, 福山裕子, 梶原茂樹, 九山浩樹, 田中耕一

    質量分析総合討論会講演要旨集  2013.9 

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  • 液体マトリックス3AQ/CHCAを用いたがんマーカータンパク質BFPの構造解析

    寶迫睦美, 九山浩樹, 中島ちひろ, 福山裕子, 吉沢明康, 川畑慎一郎, 田中耕一

    質量分析総合討論会講演要旨集  2013.9 

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  • Development of ProteomeTools - a web application suite for proteomics experiment International conference

    Tabata, T, Yoshizawa, A.C, Ohta, Y, Kusano, M, Yamamoto, N, Aoshima, K, Kajihara, S, Oda, Y, Tanak,a K

    Human Proteome Organization 12th Annual World Congress (HUPO2013)  2013.9 

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  • Cross-organism comparison of the uniqueness in protein terminal region sequences International conference

    Yoshizawa, A.C, Fukuyama, Y, Kajihara, S, Kuyama, H, Tanaka, K

    Human Proteome Organization 12th Annual World Congress (HUPO2013)  2013.9 

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  • A simple and fast label-free quantitation algorithm for LC-MS International conference

    Aoshima, K, Ikawa, M, Kimura, T, Fukuda, M, Takahashi, K, Tanaka, S, Fujita, Y, Yoshizawa, A.C, Utsunomiya, S, Kajihara, S, Tanaka, K, Oda, Y

    Human Proteome Organization 12th Annual World Congress (HUPO2013)  2013.9 

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  • iPEACH: Integrated Protein/Gene Expression Analysis Chart International conference

    Kawano, S, Yoshizawa, A.C, Mizuguchi, S, Araki, N

    Human Proteome Organization 12th Annual World Congress (HUPO2013)  2013.9 

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  • Integrated Proteomics Identified Novel Activation of Dynein IC2-GR-COX-1 Signaling by Suppression of NF1 Tumor Suppressor Gene Product, Neurofibromin, in Neuronal Cells International conference

    Kobayashi, D, Hirayama, M, Mizuguchi, S, Morikawa, T, Nagayama, M, Midorikawa, U, Wilson-Morifuji, M, Nambu-Niibori, A, Yoshizawa, A.C, Kawano, S, Araki, N

    Human Proteome Organization 12th Annual World Congress (HUPO2013)  2013.9 

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  • Identification and label-free quantitation of mass spectrometric data via freely available plug-in software, Mass++ International conference

    Tanaka, S, Fujita, Y, Yoshizawa, A.C, Utsunomiya, S, Kajihara, S, Fukuda, M, Ikawa, M, Takahashi, K, Tabata, T, Aoshima, K, Oda, Y, Tanaka, K

    Human Proteome Organization 12th Annual World Congress (HUPO2013)  2013.9 

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  • MSPTM-DB: a Known Post-Translational Modification Database and Its Implementation Web Site "ProteoAnalysis"

    吉沢明康, 田畑剛, 木村剛之, 青島健, 小田吉哉, 梶原茂樹, 田中耕一

    日本分子生物学会年会  2012.12 

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  • KEGG OC: automatically constructed comprehensive ortholog cluster based on taxonomic relation

    Moriya, Y, Nakaya, A, Katayama, T, Itoh, M, Hiranuka, K, Kawashima, S, Okuda, S, Tanaka, M, Tokimatsu, T, Yamanishi, Y, Yoshizawa, AC, Kanehisa, M, Goto, S

    日本分子生物学会年会  2012.12 

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  • JobRequest - an easy-to-use software platform for proteomic analysis - and ProteoAnalysis, its application for protein identification International conference

    Tabata, T, Yoshizawa, A.C, Kimura, T, Nakamura, T, Aoshima, K, Oda, Y, Kajihara, S, Tanaka, K

    19th International Mass Spectrometry Conference (IMSC2012)  2012.9 

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  • MSPTM-DB: a known PTM database for high-speed and accurate search available on the "ProteoAnalysis" web site International conference

    Yoshizawa, A.C, Tabata T, Kimura T, Aoshima K, Oda Y, Kajihara S, Tanaka K

    19th International Mass Spectrometry Conference (IMSC2012)  2012.9 

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  • 計算プロテオミクス手法を用いたタンパク質翻訳後修飾の同定 Invited

    吉沢 明康

    熊本大学拠点形成研究Bセミナー「プロテオミクスを基盤とした病態システムズバイオロジー教育研究拠点の構築」  2012.6 

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  • 質量分析データベース検索への翻訳後修飾情報の利用

    吉沢明康, 田畑剛, 木村剛之, 青島健, 小田吉哉, 梶原茂樹, 田中耕一

    日本分子生物学会年会  2011.12 

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  • Application of post-translational modification information in database search

    2011.9 

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  • Crystal structure of T-H protein complex of the glycine cleavage system International conference

    Okamura-Ikeda, K, Hosaka, H, Maita, N, Fujiwara, K, Yoshizawa, A.C, Nakagawa, A, Taniguchi, H

    XXII Congress and General Assembly of the International Union of Crystallography  2011.8 

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  • Genome Context of Cellulose Biosynthesis Related Gene Families

    BMB2010  2010.12 

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  • 仮想ゲルを用いたLC/MSデータの表示とタンパク質修飾の探索プログラム

    吉沢明康, 山田力志, 谷口寿章

    BMB2010  2010.12 

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  • 構造解析から明らかになったグリシン開裂酵素系T蛋白質によるアミノメチル転移の新たな反応機構

    池田和子, 保坂晴美, 真板宣夫, 藤原和子, 吉沢明康, 中川敦史, 谷口寿章

    BMB2010  2010.12 

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  • プロテオミクス解析データのデータベース化 Invited

    吉沢 明康

    疾患酵素学研究センターセミナー  2010.11 

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  • CIPRO 2.5: Ciona intestinalis Protein Database, a unique integrated repository of large-scale omics data, bioinformatic analyses, and curated annotation, with ability for user rating and comments International conference

    Endo, T, Ueno, K, Yonezawa, K, Mineta, K, Hotta, K, Satou, Y, Yamada, L, Ogasawara, M, Takahashi, H, Nakajima, A, Nakachi, M, Nomura, M, Yaguchi, J, Konno, A, Sasakura, Y, Yoshizawa, A.C, Taniguchi, H, Yamasaki, C, Sera, M, Imanishi, T, Inaba, K

    Beyond the Genome 2010  2010.10 

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  • CIPRO 2.5: Ciona intestinalis Protein integrated database with large-scale omics data, bioinformatic analyses and curated annotation, with ability for user rating and comments International conference

    Endo, T, Ueno, K, Yonezawa, K, Mineta, K, Hotta, K, Satou, Y, Yamada, L, Ogasawara, M, Takahashi, H, Nakajima, A, Nakachi, M, Nomura, M, Yaguchi, J, Konno, A, Sasakura, Y, Yoshizawa, A.C, Taniguchi, H, Yamasaki, C, Sera, M, Imanishi, T, Inaba, K

    Biocuration 2010  2010.10 

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  • CIONA INTESTINALIS PROTEIN DATABASE CIPRO SHOWS A VARIETY OF PROTEOMES FOR A SINGLE SPECIES

    遠藤俊徳, 上野恵介, 米澤弘毅, 峯田克彦, 堀田耕司, 佐藤ゆたか, 山田力志, 小笠原道生, 高橋弘樹, 中島綾子, 中地美都, 野村守, 谷口順子, 紺野在, 笹倉靖徳, 吉沢明康, 谷口寿章, 今西規, 稲葉一男

    Computational Biology Research Center Workshop 2010 (CBRC2010)  2010.7 

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  • セルロース合成関連遺伝子群のゲノムコンテキスト解析

    河野信, 橋本浩介, 吉沢明康

    セルロース学会年次大会講演要旨集  2010.7 

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  • Western Blot-like Presentation of Gel-enhanced LC/MS Data and Software-based Detection of Protein Modifications International conference

    Yoshizawa, A.C, Yamada, L, Taniguchi, H

    RECOMB(Research in Computational Molecular Biology) Satellite Conference on Computational Proteomics 2010  2010.3 

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  • Global protein profiling of ascidian C. intestinalis: toward the comprehensive understanding at the protein level International conference

    Yamada, L, Yoshizawa, A.C, Taniguchi, H

    5th International Tunicate Meeting  2009.6 

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  • Ascidian Adult Body Map: A proteomic view of adult ascidian tissues International conference

    Yoshizawa, A.C, Yamada, L, Nakachi, M, Inaba, K, Ogasawara, M, Taniguchi, H

    5th International Tunicate Meeting  2009.6 

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  • Ascidian Adult Body Map:質量分析によるホヤ・プロテオーム・データベースの構築

    吉沢明康, 山田力志, 中地美都, 稲葉一男, 小笠原道生, 谷口寿章

    日本分子生物学会第9回春季シンポジウム  2009.5 

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  • KEGG OC: 全生物種ゲノムにおけるオーソログ遺伝子のバリエーションと高速検索技術(4P-0985)

    片山俊明, 伊藤真純, 奥田修二郎, 川島秀一, 田中道廣, 時松敏明, 中谷明弘, 平糠和志, 守屋勇樹, 山西芳裕, 吉沢明康, 金久 實

    第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)  2008.12 

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  • マウス肝臓蛋白質発現の年齢依存変化のGene Ontology解析

    吉沢明康, BOLOTOVA Tatiana, 倉地幸徳, 倉地須美子

    BMB2008  2008.12 

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  • KEGG OC:全生物種ゲノムにおけるオーソログ遺伝子のバリエーションと高速検索技術(4T9-4)

    片山俊明, 伊藤真純, 奥田修二郎, 川島秀一, 田中道廣, 時松敏明, 中谷明弘, 平糠和志, 守屋勇樹, 山西芳裕, 吉沢明康, 金久實

    BMB2008  2008.12 

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  • KEGG OC:網羅的なオーソログクラスターの自動生成

    中谷明弘, 伊藤真純, 奥田修二郎, 川島秀一, 田中道廣, 時松敏明, 片山俊明, 平糠和志, 守屋勇樹, 山西芳裕, 吉沢明康, 金久實

    BMB2008  2008.12 

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  • KEGG OC:オーソログクラスターのマニュアルアノテーション

    川島秀一, 伊藤真純, 奥田修二郎, 片山俊明, 田中道廣, 時松敏明, 中谷明弘, 平糠和志, 守屋勇樹, 山西芳裕, 吉沢明康, 金久實

    BMB2008  2008.12 

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  • 網羅的データの解析による生物学的知識の抽出

    吉沢 明康

    疾患酵素学研究センターセミナー  2008.9 

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  • ゲノム決定済み生物種からの多糖類生合成酵素の網羅的抽出

    河野 信, 吉沢明康, 橋本浩介, 高木利久

    セルロース学会第15回年次大会  2008.7 

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  • Global analyses of age-related expression profiles of mouse liver proteins and database construction International conference

    Kurachi, S, Bolotova, T, Suenaga, E, Yoshizawa, AC, Kurachi, K

    The Joint 4th AOHUPO (Asian Oceania Human Proteome Organisation) and PRICPS (Pacific Rim International Conference on Protein Science)  2008.6 

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  • マウス肝臓における遺伝子発現の年齢依存変化

    吉沢明康, 末永恵美, 倉地須美子, 倉地幸徳

    日本分子生物学会第8回春季シンポジウム  2008.5 

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  • Pseudo-clique extraction method towards comprehensive clusters of orthologous genes in KEGG

    中谷明弘, 片山俊明, 川島秀一, 伊藤真純, 山西芳裕, 奥田修二郎, 守屋勇樹, 吉沢明康, 金久 實

    2007年日本バイオインフォマティクス学会年会  2007.12 

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  • DesaturaseとElongaseの網羅的探索及びその組合せによる脂肪酸予測

    橋本浩介, 吉沢明康, 奥田修二郎, 隈啓一, 五斗進, 金久實

    BMB2007  2007.12 

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  • 遺伝子エレメントASE結合核蛋白質の同定:年齢軸恒常性分子機構の確立に向けて

    倉地須美子, 笠間絵美, 田中拓, 吉沢明康, 倉地幸徳

    日本血栓止血学会誌  2007.10 

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  • Analysis of Tissue Specific Expression Patterns of Isozymes International conference

    Takarabe, M, Tsuchida, A, Fujita, M, Okuda, S, Yoshizawa, A.C, Yamada, T, Itoh, M, Goto, S, Kanehisa, M

    The 17th International Conference on Genome Informatics (GIW)  2006.12 

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  • 不飽和脂肪酸伸長酵素「Fatty Acid Elongase」の網羅的探索

    橋本浩介, 吉沢明康, 金久 實

    日本分子生物学会2006フォーラム  2006.12 

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  • Coiled-coil structures in E.coli interactome International conference

    Luban, S, Yoshizawa, A, Kihara, D

    Third Annual Indiana Bioinformatics Conference  2006.5 

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  • 細胞内輸送関与蛋白質のパラログ数変化に基づく真核細胞内輸送経路の多様化の考察

    日本分子生物学会年会  2005.12 

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  • 選択的スプライシングとタンパク質の機能の多様化の関連解析

    日本分子生物学会年会講演要旨集  2005.12 

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  • Automatic generation of KEGG OC (Ortholog Cluster) and its assignment to draft genomes International conference

    Moriya, Y, Katayama, T, Nakaya, A, Itoh, M, Yoshizawa, A.C, Okuda, S, Kanehisa, M

    The 15th International Conference on Genome Informatics (GIW)  2004.12 

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  • Analysis of the bacterial sequences recognized by RNA-binding proteins and compounds International conference

    Muto, A, Yoshizawa, A.C, Okuda, S, Itoh, M, Hattori, M, Kanehisa, M

    The 15th International Conference on Genome Informatics (GIW)  2004.12 

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  • Functional Categorization of Multiple Genomes using KEGG OC in the Genome Indices International conference

    Okuda, S, Yoshizawa, A.C, Moriya, Y, Itoh, M, Katayama, T, Goto, S, Kanehisa, M

    The 15th International Conference on Genome Informatics (GIW)  2004.12 

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  • Functional Classification of Coiled-Coil Proteins in Multiple Genomes International conference

    Yoshizawa, A.C, Okuda, S, Moriya, Y, Itoh, M, Katayama, T, Kawano, S, Okamoto, S, Kawashima, S, Kanehisa, M

    The 15th International Conference on Genome Informatics (GIW)  2004.12 

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  • Genome Wide Profiling of Glycosyltransferases and Predicted Glycan Structures from Complete and Draft Eukaryote Genomes

    河野 信, 吉沢明康, 五十嵐芳暢, 檜作好之, 金久 實

    第27回日本分子生物学会年会  2004.12 

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  • ゲノムを特徴づける種々の指標のデータベース化とそれらによる生物種進化の考察

    2004.12 

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    Language:Japanese   Presentation type:Poster presentation  

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  • SNARE分子のパラログ数変化に基づく真核細胞内輸送経路の多様化の考察

    2004.12 

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    Language:Japanese   Presentation type:Poster presentation  

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  • Integration of Biological Features of Multiple Genomes - The Construction of "Genome Indices" database - International conference

    Okuda, S, Yoshizawa, A.C, Moriya, Y, Itoh, M, Goto, S, Kanehisa, M

    The Fourth International Workshop on Bioinformatics and Systems Biology (IBSB)  2004.5 

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  • Prediction and Comparison of Coiled-Coil Proteins in Multiple Genomes International conference

    Yoshizawa, A.C, Okuda, S, Itoh, M, Katayama, S, Kawashima, S, Kanehisa, M

    The Fourth International Workshop on Bioinformatics and Systems Biology (IBSB)  2004.5 

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  • SNARE分子の分類とデータベース構築

    2003.12 

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    Language:Japanese   Presentation type:Poster presentation  

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  • Comprehensive Survey of Intracellular Transport System-Related Proteins in Complete Genomes and Draft Genomes International conference

    Yoshizawa, A.C, Itoh, M, Okuda, S, Limviphuvadh, V, Sakiyama, T, Kawashima, S, Kanehisa, M

    The 14th International Conference on Genome Informatics (GIW)  2003.12 

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  • Metabolic pathway reconstruction for malaria parasite Plasmodium falciparum International conference

    Limviphuvadh, V, Okuno, Y, Katayama, T, Goto, S, Yoshizawa, A.C, Kanehisa, M

    The 14th International Conference on Genome Informatics (GIW)  2003.12 

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  • The Construction of a Database for Ubiquitin Signaling Cascade International conference

    Sakiyama, T, Kawashima, S, Yoshizawa, AC, Kanehisa, M

    The 14th International Conference on Genome Informatics (GIW)  2003.12 

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  • Analysis of Domain Combinations in Eukaryotic Genomes International conference

    Itoh, M, Yoshizawa, A.C, Okuda, S, Goto, S, Kanehisa, M

    The 14th International Conference on Genome Informatics (GIW)  2003.12 

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  • Extraction of Organism Groups from Whole Genome Comparisons International conference

    Yamanishi, Y, Yoshizawa, A.C, Itoh, M, Katayama, T, Kanehisa, M

    The 14th International Conference on Genome Informatics (GIW)  2003.12 

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  • 配列解析に基づくSNARE分子の分類と配列モチーフ抽出

    吉沢 明康

    京都大学大学院生命科学研究科 生命科学セミナー21  2003.6 

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    Language:Japanese   Presentation type:Oral presentation (invited, special)  

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  • SNARE分子の結合特異性を反映する配列モチーフ

    吉沢明康, 川島秀一, 金久 實

    第25回日本分子生物学会年会  2002.12 

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  • Indirect relations in yeast protein interactome International conference

    Nakaya, A, Yoshizawa, A.C, Goto, S, Kanehisa, M

    The 13th International Conference on Genome Informatics (GIW)  2002.12 

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  • Comparative analysis of Rab GTPases and SNAREs in eukaryotic genomes International conference

    Yoshizawa, A.C, Kawashima, S, Kanehisa, M

    The 13th International Conference on Genome Informatics (GIW)  2002.12 

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  • Two-hybrid法・Microarray法のデータ同時比較による細胞内小胞輸送関連遺伝子の抽出

    吉沢明康, 中谷明弘, 五斗 進, 金久 實

    京都大学化学研究所第101回研究発表会  2001.12 

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  • Extraction of related genes in the vesicular transport by simultaneous comparison of two-hybrid and microarray data International conference

    Yoshizawa, A.C, Nakaya, A, Goto, S, Kanehisa, M

    The Twelfth International Conference on Genome Informatics (GIW)  2001.12 

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  • The construction of a database on the intracellular vesicular transport International conference

    Yoshizawa, A.C, Kawashima, S, Kanehisa, M

    The Eleventh Workshop on Genome Informatics (GIW)  2000.12 

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  • pathway databaseの現状

    吉沢 明康

    第21回蛋白質核酸構造理論勉強会  1999.6 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • High Resolution Cryo-Electron Microscopy Gives Clues to Transient and Metastable Structures of Subcellular Organization International conference

    Kume, N.P, Yuba, A.D, Yoshizawa, A.C, Sato, S.B, Miyazu, M, Yamazaki, M

    The 13th International Congress for Electron Microscopy  1994.7 

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  • 極低温高分解能電子顕微鏡による生体膜融合過程の観察

    吉沢明康, 山岸秀夫

    日本電子顕微鏡学会超低温技術研究部会  1991.12 

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  • 極低温電子顕微鏡によって観察した膜融合現象の諸相

    吉沢明康, 弓場亜紀子, 山岸秀夫, 高橋信之, 久米直明

    日本生物物理学会第29回年会  1991 

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  • 極低温電子顕微鏡を用いたインフルエンザウイルス膜融合過程の観察

    吉沢 明康, 弓場 亜紀子, 佐藤 智, 山岸 秀夫, 大西 俊一, 久米 直明

    日本生物物理学会年会講演予稿集  1990.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • High Resolution Cryo-Electron Microscopy Sheds a New Light upon Biomembrane Architecture International conference

    Kume, N.P, Yuba, A.D, Yoshizawa, A.C, Sato,S.B, Fujiyoshi, Y

    The 12th International Congress for Electron Microscopy  1990.8 

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  • 極低温高分解能電子顕微鏡による生体膜融合過程追跡の試み

    弓場亜紀子, 吉沢明康, 佐藤 智, 久米直明

    日本電子顕微鏡学会第46回学術講演会  1990.5 

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  • 膜小胞の曲率が膜融合活性に及ぼす影響

    吉沢明康, 村田昌之, 大西俊一

    日本生物物理学会第26回年会  1988 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • Development of a Time-Resolved Microfluorimeter with a Synchroscan Streak Camera and Its Application to Studies of Cell Membranes International conference

    Kusumi, A, Tsuji, A, Murata, M, Sako, Y, Yoshizawa, A.C, Hayakawa, T, Ohnishi, S

    SPIE (The International Society for Optical Engineering) Proceedings  1988 

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  • 時間分解顕微蛍光光度計の開発と細胞膜の動的構造研究への応用

    楠見明弘, 辻 明彦, 村田昌之, 佐甲靖志, 吉沢明康, 早川 毅, 大西俊一

    日本生物物理学会第25回年会  1987 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • IB-7 時間分解顕微蛍光光度計の開発と細胞膜研究への応用

    楠見 明弘, 辻 明彦, 村田 昌之, 佐甲 靖志, 吉沢 明康, 早川 毅

    日本組織細胞化学会総会プログラムおよび抄録集  1987 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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Industrial property rights

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Works

  • Mass++ ver.4

    Tanaka, S, Murase, M, Kato, M, Yamamoto, H, Tabata, T, Kusano, M, Kawano, S, Goto, S, Ishihama, Y, Yoshizawa, AC

    2018

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    Work type:Software  

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  • jPOST

    Moriya, Y, Kawano, S, Okuda, S, Watanabe, Y, Matsumoto, M, Takami, T, Kobayashi, D, Yamanouchi, Y, Araki, N, Yoshizawa, AC, Tabata, T, Iwasaki, M, Sugiyama, N, Tanaka, S, Goto, S, Ishihama, Y

    2016

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    Work type:Database science  

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  • Mass++ ver.2.7.4/2.7.5

    Tanaka, S, Fujita,Y, Parry, H.E, Yoshizawa, AC, Morimoto, K, Murase, M, Yamada, Y, Yao, J, Utsunomiya, S, Kajihara, S, Fukuda, M, Ikawa, M, Tabata, T, Takahashi, K, Aoshima, K, Nihei, Y, Nishioka, T, Oda, Y, Tanaka, K

    2014

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    Work type:Software  

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  • ProteinCarta

    Yoshizawa, AC, Fukuyama, Y, Kajihara, S, Kuyama, H, Tanaka, K

    2014

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    Work type:Web Service  

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  • KEGG OC

    Nakaya, A, Katayama, T, Itoh, M, Hiranuka, K, Kawashima, S, Moriya, Y, Okuda, S, Tanaka, M, Tokimatsu, T, Yamanishi, Y, Yoshizawa, AC, Kanehisa, M, Goto, S

    2012

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    Work type:Database science  

    DOI: 10.1093/nar/gks1239

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  • CIPRO (Ciona intestinalis Protein Database)

    Endo, T, Ueno, K, Yonezawa, K, Mineta, K, Hotta, K, Satou, Y, Yamada, L, Ogasawara, M, Takahashi, H, Nakajima, A, Nakachi, M, Nomura, M, Yaguchi, J, Sasakura, Y, Yamasaki, C, Sera, M, Yoshizawa, AC, Imanishi, T, Taniguchi, H, Inaba, K

    2009

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    Work type:Database science  

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  • The SNARE Map

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    Work type:Database science  

    (閉鎖)

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Research Projects

  • Development of an automated and quick genome annotation tool for omics analysis

    Grant number:050RP2023

    2023.6 - 2024.3

    System name:The Joint Research Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

    Yoshizawa, AC, Moriya, Y

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    Authorship:Principal investigator  Grant type:Competitive

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  • Development of a web tool for sequence information acquisition and the novel amino acid sequence identification resource against whole genome sequence data using high-speed character string search

    Grant number:029RP2022

    2022.6 - 2023.3

    System name:The Joint Research Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

    Yoshizawa, AC, Naito, Y, Goto, S

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    Authorship:Principal investigator  Grant type:Competitive

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  • Development of the novel amino acid sequence identification resource against whole genome sequence data by high-speed character string search

    Grant number:018RP2021

    2021.7 - 2022.3

    System name:The Joint Research Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

    Yoshizawa, AC, Naito,Y, Goto, S

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    Authorship:Principal investigator  Grant type:Competitive

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  • Development of the novel amino acid sequence identification resource against whole genome sequence data by high-speed character string search

    Grant number:019RP2020

    2020.7 - 2021.3

    System name:The Joint Research Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

    Yoshizawa, AC, Naito, Y, Goto, S

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  • Development of novel methodology for amino acid de novo sequencing by mass spectrometry

    Grant number:20H03245

    2020.4 - 2023.3

    System name:Grant-in-Aid for Scientific Research (B)

    Research category:Grant-in-Aid for Scientific Research (B)

    Awarding organization:JSPS

    Kawano, S, Iwasaki, M, Kobayashi, D, Yoshizawa, AC

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\17680000 ( Direct Cost: \13600000 、 Indirect Cost:\4080000 )

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  • Development and application of the novel protein sequence identification resource by high-speed character string search and RDF

    Grant number:017RP2019

    2019.7 - 2020.3

    System name:The Joint Research Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

    Yoshizawa, AC, Naito,Y, Moriya, Y, Kawano, S, Tabata, T, Ishihama, Y, Goto, S

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  • Computational Mass Spectrometry Hackathon Pre-meeting

    Grant number:005RM2019

    2019.7 - 2020.3

    System name:The Joint Research Meeting Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

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  • Development and application of the novel protein/nucleic acid sequence identification resource by high-speed character string search and RDF

    Grant number:005RP2018

    2018.6 - 2019.3

    System name:The Joint Research Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

    Yoshizawa, AC, Naito, Y, Kato, M, Moriya, Y, Tabata, T, Uchiyama, I, Kawano, S, Ishihama, Y, Goto, S

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    Authorship:Principal investigator  Grant type:Competitive

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  • Computational Mass Spectrometry Hackathon Symposium

    Grant number:002RM2018

    2018.6 - 2019.3

    System name:The Joint Research Meeting Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

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    Authorship:Principal investigator  Grant type:Competitive

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  • 2nd Hackathon on Computational Mass Spectrometry2

    2018.4 - 2019.3

    System name:Subsidies for Conferences

    Awarding organization:Kato Memorial Bioscience Foundation

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    Authorship:Principal investigator  Grant type:Competitive

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  • Pre-Meeting for Computational Mass Spectrometry Hackathon

    Grant number:006RM2017

    2017.11 - 2018.3

    System name:The Joint Research Meeting Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

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    Authorship:Principal investigator  Grant type:Competitive

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  • Development of the novel protein identification resource by high-speed character string search and RDF

    Grant number:013RP2017

    2017.10 - 2018.3

    System name:The Joint Research Program, ROIS-DS-JOINT

    Awarding organization:ROIS DS

    Yoshizawa, AC, Naito,Y, Moriya, Y, Kawano, S, Tabata, T, Ishihama, Y, Goto, S

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    Authorship:Principal investigator  Grant type:Competitive

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  • Computational Mass Spectrometry Hackathon

    2017.4 - 2018.3

    System name:Subsidies for Conferences

    Awarding organization:Kato Memorial Bioscience Foundation

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    Authorship:Principal investigator  Grant type:Competitive

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  • Development of mass peak picking method by deep learning

    Grant number:16K00390

    2016.4 - 2019.3

    System name:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    Yoshizawa Akiyasu, TABATA Tsuyoshi, IWASAKI Mio, KAWANO Shin, GOTO Susumu, ISHIHAMA Yasushi, TAKIGAWA Ichigaku

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

    We developed a novel method of “peak picking,” an indispensable step in mass spectrometry data analysis, by deep learning in neural network. Mass peaks used for training data were those that were picked and identified as peptides with high scores by conventional methods. The current implementation of our classifier has almost equal detection performance as the conventional methods, and can also detect mass peaks that could not be detected by conventional methods.

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  • Comprehensive analysis of eukaryotic operons using proteomic information and comparative genomics

    Grant number:23510245

    2011.4 - 2012.3

    System name:Grant-in-Aid for Scientific Research (C) [Declined after adoption]

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:JSPS

    Yoshizawa, AC, Yamada, L, Okuda, S, Moriya,Y

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\5590000 ( Direct Cost: \4300000 、 Indirect Cost:\1290000 )

    Declined after adoption due to the bylaws of the company

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Teaching Experience (researchmap)

  • Theory of Bioinformatics/Advanced Bioinformatics

    2021.10
    Institution name:Graduate School of Pharmaceutical Sciences/Science, Kyoto University

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    Level:Postgraduate  Country:Japan

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  • Advanced Fundamental Physical Chemistry I, II/Advanced Pharmaceutical Research II

    2018.4
    -
    2020.9
    Institution name:Graduate School of Pharmaceutical Sciences, Kyoto University

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    Level:Graduate (liberal arts) 

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  • 研究方法論(臨床研究・ゲノムインフォマティクス実践論)

    2018.4
    -
    2019.9
    Institution name:岡山大学大学院医歯薬学総合研究科

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    Level:Postgraduate 

    担当:「プロテオーム解析のバイオインフォマティクス」

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  • Information and Communication (General literacy/Spread sheet)

    2001.4
    -
    2007.3

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    Level:Undergraduate (liberal arts) 

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  • Basic Exercises in Pedagogy (Lectures on Physics and Chemistry)

    1996.4
    -
    2001.3

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    Level:Undergraduate (specialized) 

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  • Information Processing

    1995.4
    -
    2002.3

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    Level:Undergraduate (liberal arts) 

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  • Introduction to Computer Science

    1995.4
    -
    1997.3
    Institution name:Seisen College

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    Level:Undergraduate (specialized) 

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  • Programming Exercise I, II 1

    1995.4
    -
    1997.3
    Institution name:Seisen College

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    Level:Undergraduate (specialized) 

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  • Elementary Science (Lectures on Physics and Chemistry)

    1993.4
    -
    1996.3

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    Level:Undergraduate (specialized) 

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  • Specialized pedagogy in Science (chemistry/physics experiment)

    1991.10
    -
    2001.3

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    Level:Undergraduate (specialized) 

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Academic Activities

  • 質量分析インフォマティクス研究会・第8回公開ワークショップ(2023年)「構造生物学に質量分析で挑む」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2023.5

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  • 第1回・質量分析インフォマティクス沖縄ミートアップ(2023年)

    Role(s): Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2023.2

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  • 質量分析インフォマティクス研究会・第7回公開ワークショップ ONLINE(2022年)「質量分析オミクスデータを深く読む」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2022.4

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  • Reviewer, "Proteome Letters"

    Role(s): Peer review

    2022

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    Type:Peer review 

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  • 日本プロテオーム学会(JPrOS) 2021年大会・シンポジウム「バイオインフォマティクスが担う多様なオミクス解析」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    日本プロテオーム学会  2021.7

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  • 質量分析インフォマティクス研究会・第6回公開ワークショップ ONLINE(2021年)「質量分析情報で代謝を理解する」

    Role(s): Planning, management, etc.

    質量分析インフォマティクス研究会  2021.6

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    Type:Competition, symposium, etc. 

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  • 質量分析インフォマティクス研究会・第5回公開ワークショップ ONLINE(2020年)「質量分析とデータ科学で生命に迫る」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2020.8

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  • jPOSTデータ解析ショートコース

    Role(s): Planning, management, etc.

    JPrOS2019/JES2019合同大会(日本プロテオーム学会・日本電気泳動学会合同大会)サテライトイベント  2019.7

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    Type:Competition, symposium, etc. 

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  • 第3回質量分析インフォマティクス・ハッカソン(2019年)

    Role(s): Planning, management, etc.

    質量分析インフォマティクス研究会(DBCLS国内版バイオハッカソン(BH19.7)と共同開催)  2019.7

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    Type:Competition, symposium, etc. 

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  • 質量分析インフォマティクス研究会・第4回公開ワークショップ(2019年)「データ科学が拡大する質量分析の地平線」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2019.3

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    Type:Competition, symposium, etc. 

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  • メタオミクスワークショップ in 京都 2019

    Role(s): Planning, management, etc.

    京都大学融合チーム研究プロジェクトSPIRITS・メタプロテオミクスプロジェクト  2019.3

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  • Reviewer & Curator, "Journal of Proteome Data and Methods" International contribution

    Role(s): Peer review

    2019

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    Type:Peer review 

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  • BoFセッション「質量情報から生物情報へ」(第7回生命医薬情報学連合大会(IIBMP2018: 2018年日本バイオインフォマティクス学会(JSBi)年会))

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    日本バイオインフォマティクス学会  2018.9

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  • 第2回質量分析インフォマティクス・ハッカソン(2018年)

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会(DBCLS国内版バイオハッカソン(BH18.7)と共同開催)  2018.7

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    Type:Competition, symposium, etc. 

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  • International Proteogenome Workshop 2018

    Role(s): Planning, management, etc.

    MSP2018 (Mass Spectrometry and Proteomics 2018) Satellite Workshop  2018.5

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    Type:Competition, symposium, etc. 

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  • 4C-O2-P「情報科学から迫る質量分析・オミクスの世界」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    MSP2018(Mass Spectrometry and Proteomics 2018: 日本質量分析学会(MSSJ)・日本プロテオーム学会(JPrOS)・アジアオセアニア・ヒトプロテオーム機構(AOHUPO)合同大会)  2018.5

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    Type:Competition, symposium, etc. 

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  • 質量分析インフォマティクス研究会・第3回公開ワークショップ(2018年)「質量分析法とオミクス計算処理」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2018.4

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    Type:Competition, symposium, etc. 

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  • ワークショップ2PW23「オミクス研究から実用的システム生物学の構築へ」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    2017年度生命科学系学会合同年次大会(ConBio2017)(第40回日本分子生物学会年会)2  2017.12

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  • 第1回質量分析インフォマティクス・ハッカソン(2017年)

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会(DBCLS国内版バイオハッカソン(BH17.11)と共同開催)  2017.11 - 2017.12

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    Type:Competition, symposium, etc. 

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  • BoFセッション「質量分析とケモインフォマティクスの実りある連携」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    第6回生命医薬情報学連合大会(IIBMP2017: 2017年日本バイオインフォマティクス学会(JSBi)年会)  2017.9

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  • 質量分析インフォマティクス研究会・第2回公開ワークショップ(2017年)「質量分析研究に於ける情報処理の現在と今後」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2017.2

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  • 質量分析インフォマティクス研究会・第1回公開ワークショップ(2016年度)「質量分析データ解析のための計算科学」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    質量分析インフォマティクス研究会  2016.10

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  • 質量分析インフォマティクス研究会(JCompMS, 旧ms-bio.info) 設立(発起人・世話人)

    Role(s): Planning, management, etc.

    (日本バイオインフォマティクス学会)  2016.4

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    Type:Academic society, research group, etc. 

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  • BoFセッション「質量分析インフォマティクスとデータベース」

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    第4回生命医薬情報学連合大会(IIBMP2015: 2015年日本バイオインフォマティクス学会(JSBi)年会)  2015.10

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  • Mass++ユーザー会公開ワークショップ

    Role(s): Planning, management, etc.

    Mass++ユーザー会(オープンソース・プロジェクト)  2015.8

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  • 日本プロテオーム学会2015年会(JHUPO第13回大会)トレーニングコース

    Role(s): Planning, management, etc.

    日本プロテオーム学会2015年会(JHUPO第13回大会)  2015.7

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    Type:Competition, symposium, etc. 

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  • Mass++ユーザー会 設立(発起人・世話人)

    Role(s): Planning, management, etc.

    Mass++ユーザー会(オープンソース・プロジェクト)  2015.6

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  • Reviewer, "Current Protein and Peptide Science" International contribution

    Role(s): Peer review

    2010

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    Type:Peer review 

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  • Reviewer, "International Journal of Molecular Sciences" International contribution

    Role(s): Peer review

    2010

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    Type:Peer review 

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