2022/11/29 更新

写真a

オガワ ヒロシ
小川 祐司
OGAWA Hiroshi
所属
教育研究院 医歯学系 歯学系列 教授
歯学部 歯学科 教授
医歯学総合研究科 口腔生命科学専攻 口腔健康科学 教授
職名
教授
外部リンク

学位

  • 博士(歯学) ( 2001年3月   新潟大学 )

  • 修士(歯学) ( 1996年12月   シドニー大学 )

研究キーワード

  • Preventive Dentistry

  • Dental Public Health

  • 口腔衛生学

  • 国際口腔保健学

  • 予防歯科学

研究分野

  • ライフサイエンス / 社会系歯学

経歴(researchmap)

  • 新潟大学   大学院医歯学総合研究科   教授

    2018年10月 - 現在

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  • 世界保健機関   国際口腔保健部   歯科医官

    2014年4月 - 2017年4月

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  • 新潟大学   大学院医歯学総合研究科   准教授

    2011年10月 - 2018年9月

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  • 新潟大学   医歯学総合病院   講師

    2010年4月 - 2011年9月

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  • 世界保健機関   国際口腔保健部   歯科医官代行

    2008年5月 - 2008年6月

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  • 世界保健機関   国際口腔保健部   短期研究員

    2003年9月 - 2005年3月

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  • 新潟大学   医歯学総合病院   助教

    2001年12月 - 2010年3月

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経歴

  • 新潟大学   歯学部 歯学科   教授

    2018年10月 - 現在

  • 新潟大学   医歯学総合研究科 口腔生命科学専攻 口腔健康科学   教授

    2018年10月 - 現在

  • 新潟大学   歯学部 歯学科   准教授

    2011年10月 - 2018年9月

  • 新潟大学   医歯学総合研究科 口腔生命科学専攻 口腔健康科学   准教授

    2011年10月 - 2018年9月

  • 新潟大学   医歯学総合病院 矯正・小児系歯科 予防歯科診療室   講師

    2010年4月 - 2011年9月

  • 新潟大学   医歯学総合病院 矯正・小児系歯科   助教

    2003年10月 - 2010年3月

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学歴

  • 新潟大学   大学院歯学研究科   予防歯科学

    1997年4月 - 2001年3月

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    国名: 日本国

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  • シドニー大学   大学院歯学研究科   歯科公衆衛生学

    1995年1月 - 1996年12月

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    国名: オーストラリア連邦

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  • 日本大学   松戸歯学部   歯学科

    1988年4月 - 1994年3月

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所属学協会

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委員歴

  • 日本学校歯科医会   国際渉外委員  

    2019年6月 - 現在   

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  • 日本口腔衛生学会   禁煙推進委員会委員  

    2019年5月 - 現在   

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    団体区分:学協会

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  • 日本口腔衛生学会   国際交流委員会委員長  

    2019年5月 - 現在   

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    団体区分:学協会

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  • FDI 国際歯科連盟   公衆衛生委員  

    2018年10月 - 現在   

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    団体区分:その他

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  • 新潟市   歯科保健推進会議委員  

    2018年4月 - 現在   

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    団体区分:自治体

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  • 日本歯科医師会   国際渉外委員  

    2017年6月 - 現在   

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    団体区分:学協会

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  • WHO 世界保健機関   Expert for Clinical Consortium on Healthy Ageing  

    2017年6月 - 現在   

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    団体区分:その他

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  • 日本口腔衛生学会   地域口腔保健委員会委員  

    2017年4月 - 現在   

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    団体区分:学協会

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留学歴

  • 世界保健機関   Dental Officer

    2014年4月 - 2017年3月

  • 世界保健機関   Short term professional

    2003年9月 - 2005年8月

取得資格

  • 歯科医師

 

論文

  • Interaction between serum vitamin C levels and smoking on the periodontal condition in older adults. 国際誌

    Akihiro Yoshihara, Keisuke Nakashima, Kana Suwama, Ayuko Odajima, Takayuki Yamaga, Hiroshi Ogawa

    Journal of periodontal research   2022年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND AND OBJECTIVES: Several epidemiological studies have reported that smokers have a higher prevalence and severity of periodontal disease than do nonsmokers, and that smoking negatively affects nutritional status and is associated with a reduced intake of antioxidants, particularly vitamin C. The present investigation aimed to examine the relationship between serum vitamin C levels and smoking and its influence on the periodontal condition in older adults. MATERIALS AND METHODS: A total of 353 respondents met the inclusion criteria and were enrolled in the present study. The periodontal status of the study participants was determined through examinations of one or more residual teeth, which included a measurement of the probing pocket depth (PPD) and clinical attachment level (CAL) at six regions of each tooth. Blood samples were collected during the dental examinations and then sent to a laboratory to evaluate serum vitamin C and cotinine levels. A serum cotinine concentration of 100 ng/ml was considered a relevant threshold for active smoking. After dividing the participants into two groups according to serum cotinine levels, Poisson regression analysis was carried out to compare vitamin C levels with the prevalence rate ratio (PRR) for periodontal condition markers for each group based on serum cotinine levels. RESULTS: We evaluated differences in the PRR of serum vitamin C tertiles between participants with high (≥100 ng/ml) or low (<100 ng/ml) serum cotinine levels after adjusting for sex, the use of interdental brushes or dental floss, and the number of teeth. A negative tendency between the PRR of vitamin C tertiles for the PPD or CAL was seen for both groups. Especially, a bigger difference was observed in the group with high serum cotinine levels. The PRR of the first tertiles in the high serum cotinine group was 5.03, compared with 2.69 in the low serum cotinine group (relative risk: 1.9). CONCLUSION: The results of this study suggest a potential association between vitamin C levels and the periodontal condition, which may be influenced by smoking status.

    DOI: 10.1111/jre.12988

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  • 生活習慣病対策における歯科口腔保健のあり方 特定健診・標準的質問票に咀嚼に関する質問が組み込まれたことを踏まえて

    深井 穫博, 大内 章嗣, 福田 英輝, 岡田 寿朗, 佐々木 健, 安藤 雄一, 小川 祐司, 竹内 研時, 山中 史教, 小畑 充彦, 長 優子, 田所 大典, 皆川 久美子, 神原 正樹, 宮崎 秀夫, 嶋崎 義浩, 花田 信弘, 日本口腔衛生学会地域口腔保健委員会

    口腔衛生学会雑誌   72 ( 2 )   122 - 129   2022年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 高齢者における血漿中抗Porphyromonas gingivalis抗体価と心房細動との関連

    星野 剛志, 金子 昇, 葭原 明弘, 諏訪間 加奈, 小川 祐司

    新潟歯学会雑誌   51 ( 2 )   111 - 112   2021年12月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

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  • 高齢者における血漿中抗Porphyromonas gingivalis抗体価と心房細動との関連

    星野 剛志, 金子 昇, 葭原 明弘, 諏訪間 加奈, 小川 祐司

    新潟歯学会雑誌   51 ( 2 )   111 - 112   2021年12月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

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  • 腎機能と自己申告による現在歯数との関連(魚沼コホート調査より)

    皆川 久美子, 葭原 明弘, 宮本 茜, 諏訪間 加奈, 小川 祐司

    日本公衆衛生学会総会抄録集   80回   439 - 439   2021年11月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

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  • Diet and root surface caries in a cohort of older Japanese. 国際誌

    Akihiro Yoshihara, Kana Suwama, Akane Miyamoto, Reiko Watanabe, Hiroshi Ogawa

    Community dentistry and oral epidemiology   49 ( 3 )   301 - 308   2021年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVES: Root surface caries experience tends to increase with age. The purpose of this longitudinal study was to evaluate the relationship between aspects of dietary intake, including milk and sucrose in coffee or tea (SCT), and root surface caries in older Japanese individuals. METHODS: 303 community-dwelling older individuals (age 75 years) were enrolled for analysis. All participants underwent a dental examination at baseline and then annually from 2003 to 2008 (ie six times over a 5-year period). A disease event was considered to have occurred when root surface caries was detected on a previously sound or nonexposed root surface. Over the observation period, disease events in each year were counted. Dietary habits during the preceding month were evaluated using a brief self-administered diet history questionnaire (BDHQ) in 2003 and 2008. Poisson regression analysis performed crude and adjusted increment-rate ratios (IRRs) for root surface caries and the intake of milk and SCT. RESULTS: The adjusted increment-rate ratio (IRR) of the increment of root surface caries for participants in the highest SCT tertile was 1.72 (95%CI: 1.40-2.14) compared with the referent group. In addition, for the amount of milk intake, the adjusted IRR in the highest tertile was 0.63 (95% CI: 0.51-0.78) compared with the referent group. CONCLUSIONS: Much SCT and low milk intake were associated with the increment of root surface caries in community-dwelling older people in Japan. These findings suggest that to help prevent root surface caries, community-dwelling older people in Japan should consume adequate amounts of milk daily and limit their intake of SCT.

    DOI: 10.1111/cdoe.12602

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  • A population-based cross-sectional study of the association between periodontitis and arterial stiffness among the older Japanese population. 国際誌

    Masanori Iwasaki, Yumi Kimura, Takayuki Yamaga, Naomune Yamamoto, Motonao Ishikawa, Taizo Wada, Ryota Sakamoto, Yasuko Ishimoto, Michiko Fujisawa, Kiyohito Okumiya, Kuniaki Otsuka, Kozo Matsubayashi, Hiroshi Ogawa

    Journal of periodontal research   56 ( 2 )   423 - 431   2021年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVE: To investigate the potential association between periodontitis and arterial stiffness among the older Japanese population. BACKGROUND: The prevalence of periodontitis is increasing in Japanese older adults. Arterial stiffness increases the risks of cardiovascular events and death, morbidity, and dementia. METHODS: This secondary analysis of data from a cross-sectional study evaluated the periodontal inflamed surface area (PISA), reflecting the amount of inflamed periodontal tissue that was estimated by a full-mouth periodontal examination. Severe periodontitis was defined per the parameters provided by the Centers for Disease Control/American Academy of Periodontology. The Cardio-Ankle Vascular Index (CAVI) was used for measuring the overall stiffness of the artery, and higher CAVI indicated increased arterial stiffness. An ordinal logistic regression model was used to evaluate the association between periodontitis and arterial stiffness. RESULTS: The analysis included 185 Japanese adults [35% men; age, mean (standard deviation) 80.2 (4.4) years]. The average PISA and the prevalence of severe periodontitis were 64.4 mm2 and 27.6%, respectively; 54 (29.2%), 56 (30.3%), and 75 (40.5%) participants were stratified to the CAVI < 9, 9 ≤ CAVI <10, and CAVI ≥ 10 groups, respectively. After adjusting for potential confounders, the odds ratio of the prevalence and severity of arterial stiffness evaluated using CAVI was 1.06 [95% confidence interval (CI) 1.01 to 1.10] for PISA per 10 mm2 and 2.12 (95% CI 1.09 to 4.11) for severe periodontitis. CONCLUSION: Periodontitis was associated with arterial stiffness among Japanese older adults. Further studies are needed to investigate whether arterial stiffness is an intermediate factor in the pathway between periodontitis and systemic diseases, including cardiovascular disease and dementia.

    DOI: 10.1111/jre.12835

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  • 65歳以上のメタボリックシンドローム有病者における現在歯数と心の健康状態の関連 魚沼コホート調査より

    皆川 久美子, 葭原 明弘, 諏訪間 加奈, 小川 祐司

    口腔衛生学会雑誌   71 ( 増刊 )   111 - 111   2021年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 65歳以上のメタボリックシンドローム有病者における現在歯数と心の健康状態の関連 魚沼コホート調査より

    皆川 久美子, 葭原 明弘, 諏訪間 加奈, 小川 祐司

    口腔衛生学会雑誌   71 ( 増刊 )   111 - 111   2021年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 腎機能と歯の本数との関連(魚沼コホート胴査より)

    皆川 久美子, 葭原 明弘, 諏訪間 加奈, 小川 祐司

    口腔衛生学会雑誌   71 ( 1 )   52 - 52   2021年1月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 地域在住の後期高齢者における転倒リスク因子としての現在歯数

    渡辺 真光, 濃野 要, 星野 剛志, 田村 浩平, 小川 祐司

    新潟歯学会雑誌   50 ( 2 )   119 - 119   2020年12月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

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  • 地域在住後期高齢者における残存歯数と転倒の関連

    渡辺 真光, 濃野 要, 星野 剛志, 田村 浩平, 角田 聡子, 岩崎 正則, 石本 恭子, 木村 友美, 坂本 龍太, 小川 祐司

    日本老年医学会雑誌   57 ( Suppl. )   134 - 134   2020年7月

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    記述言語:日本語   出版者・発行元:(一社)日本老年医学会  

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  • The relationship between sucrose intake in coffee or tea, and root or coronal caries in an elderly Japanese population. 査読 国際誌

    A Yoshihara, K Suwama, A Miyamoto, R Watanabe, H Ogawa

    Community dental health   2020年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVES: Few studies have examined the effect of sucrose intake in coffee or tea (SCT) on dental caries, especially root caries, in elderly people. The purpose of the present study was to examine the associations between SCT and the prevalence of root or coronal caries in community-dwelling elderly Japanese. METHODS: Participants were 370 elders aged 75 years from a larger cohort study of elders in Niigata City, Japan. Dietary habits during the preceding month were assessed with a validated brief self-administered diet history questionnaire (BDHQ). The caries examination was conducted using mirror and ball-pointed periodontal probes under artificial light. Poisson regression analysis was performed to analyze the prevalence-rate ratios (PRRs) between SCT and the root or coronal caries. The number of root or coronal caries was selected as the dependent variable for the analysis. Then, SCT (tertiles labeled low, medium and high) and other 4 variables were selected as independent variables. RESULTS: The PRRs between the number of root caries lesions and SCT were signifi cantly higher in the second (medium intake, 1.38, p ⟨ 0.001) and third tertiles (high intake, 2.07, p ⟨ 0.001). Similar tendencies were seen for the number of coronal caries lesions (PRRs in the second and third tertiles 1.74 and 2.46, respectively, both p ⟨ 0.001). CONCLUSION: A significant positive relationship was observed between sucrose in coffee and tea and the number of coronal or root caries lesions in community-dwelling elderly Japanese.

    DOI: 10.1922/CDH_00011Yoshihara05

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  • 歯周病原性以外の口腔微生物への喫煙の影響 文献レビュー

    埴岡 隆, 内藤 麻利江, 谷口 奈央, 重石 英生, 杉山 勝, 森田 学, 竹下 徹, 花田 信弘, 小島 美樹, 小川 祐司, 山本 龍生

    口腔衛生学会雑誌   70 ( 増刊 )   165 - 165   2020年3月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 乳歯における癒合歯および形成不全とその原因についての臨床的考察

    宮本 茜, 葭原 明弘, 皆川 久美子, 金子 昇, 濃野 要, 市川 優, 星野 剛志, 藤山 友紀, 平野 真弓, 小川 祐司

    口腔衛生学会雑誌   70 ( 増刊 )   106 - 106   2020年3月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 学童期における唾液中乳酸脱水素酵素とストレスの関連について 査読

    田村 浩平, 葭原 明弘, 諏訪間 加奈, 角田 聡子, 岩崎 正則, 安細 敏弘, 小川 祐司

    口腔衛生学会雑誌   70 ( 1 )   47 - 48   2020年1月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 歯肉自己観察の歯周病スクリーニングにおける有用性

    市川 優, 葭原 明弘, 山田 智子, 杉本 智子, 林 悠子, 皆川 久美子, 小川 祐司

    口腔衛生学会雑誌   70 ( 1 )   47 - 47   2020年1月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • Smoking and periodontal microorganisms. 国際誌

    Takashi Hanioka, Manabu Morita, Tatsuo Yamamoto, Koji Inagaki, Pao-Li Wang, Hiroshi Ito, Toshiya Morozumi, Toru Takeshita, Nao Suzuki, Hideo Shigeishi, Masaru Sugiyama, Kouji Ohta, Toru Nagao, Nobuhiro Hanada, Miki Ojima, Hiroshi Ogawa

    The Japanese dental science review   55 ( 1 )   88 - 94   2019年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Resolution of dysbiosis following treatment for periodontal disease and tobacco dependence has been reported in longitudinal intervention studies. In the present report, we evaluated the biological findings regarding the effect of smoking on the periodontal microbiome. A standardized electronic search was conducted using MEDLINE; overall, 1099 papers were extracted. Studies that addressed the relationship between tobacco and periodontal pathogens were included. Finally, 42 papers were deemed appropriate for the present review. Functional changes in periodontal pathogens exposed to nicotine and cigarette smoke extract support the clinical findings regarding dysbiosis of the subgingival microbiome. Dysbiosis of the periodontal microbiome was presented in smokers regardless of their periodontal condition (healthy, gingivitis, or periodontitis) and remained significant only in smokers even after the resolution of experimentally-induced gingivitis and following reduction of clinical signs of periodontitis with non-surgical periodontal treatment and over 3 months post-therapy. Based on these findings, smoking cessation in periodontitis patients is beneficial for promoting a health-compatible subgingival microbial community. To maximize the benefits of these interventions in dental settings, further studies on periodontal microbiome are needed to elucidate the impact of tobacco intervention on preventing recurrence of periodontal destruction in the susceptible subjects.

    DOI: 10.1016/j.jdsr.2019.03.002

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  • 加齢に伴う歯数の変化の軌跡と生命予後の関連 高齢期に28歯を維持することの意義

    岩崎 正則, 佐藤 美寿々, 皆川 久美子, 安細 敏弘, 小川 祐司, 葭原 明弘

    口腔衛生学会雑誌   69 ( 3 )   131 - 138   2019年7月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

    本研究の目的は地域在住高齢者における歯数の加齢に伴う変化の軌跡(加齢変化パターン)を類型化し、生命予後との関連を明らかにすることである。70歳から80歳までの10年間に毎年実施した調査に参加した、ベースライン時点で20歯以上を有する299名(男性154名・女性145名)のデータを用いた。70歳から80歳までの歯数の変化に対して、異なる関数形の軌跡をもつグループに分割することを目的に集団軌跡モデルを適応した。その後、歯数の加齢変化パターンと生命予後の関連を評価することを目的にCox比例ハザードモデルによる生存解析を実施した。追跡期間(70歳から85歳)中の総死亡をアウトカムとし、加齢変化パターンごとのハザード比(HR)を算出した。歯数の加齢変化は3つ(28歯維持群、中間-減少群、少ない-減少群)に類型化された。生存解析の結果、少ない-減少群と比較して28歯維持群は総死亡リスクが有意に低いことがわかった(adjusted HR=0.50、95%信頼区間=0.28-0.89)。結論として70歳で20歯以上を有する地域在住高齢者において、その後10年間の歯数の加齢変化は一様でなく、生命予後の観点からはできる限り多くの歯を維持することが重要であり、28歯を維持できれば最も望ましいことが本研究から示唆された。(著者抄録)

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  • Periodontitis, periodontal inflammation, and mild cognitive impairment: A 5-year cohort study. 査読 国際誌

    Masanori Iwasaki, Yumi Kimura, Hiroshi Ogawa, Takayuki Yamaga, Toshihiro Ansai, Taizo Wada, Ryota Sakamoto, Yasuko Ishimoto, Michiko Fujisawa, Kiyohito Okumiya, Hideo Miyazaki, Kozo Matsubayashi

    Journal of periodontal research   54 ( 3 )   233 - 240   2019年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND AND OBJECTIVES: Identification of modifiable factors for mild cognitive impairment (MCI) is important since individuals with MCI are at a high risk of dementia and disability. Previous studies have suggested a potential association between periodontitis and cognitive impairment, but the results remain inconclusive. We designed a 5-year longitudinal study to explore the association between MCI and periodontitis and periodontal inflammation in older adults. METHODS: This study included 179 community-dwelling dentate individuals (62 men and 117 women, average age: 80.1 years). A full-mouth periodontal examination at six sites per tooth was performed at baseline. Case definitions provided by the European Workshop in Periodontology Group C (EWP definition) and the Centers for Disease Control/American Academy of Periodontology (CDC/AAP definition) were used to define severe periodontitis. Additionally, the periodontal inflamed surface area (PISA), reflecting the amount of inflamed periodontal tissue, was calculated using clinical periodontal parameters. Follow-up cognitive examinations for MCI diagnosis were performed by neurologists 1, 2, 3, and 5 years after baseline. Odds ratios (ORs) for MCI according to the presence of periodontitis and periodontal inflammation at baseline were calculated using multilevel mixed-effects logistic regression. RESULTS: At baseline, 56.4% and 27.4% of the participants had severe periodontitis by the EWP and CDC/AAP definitions, respectively. After adjusting for follow-up period and other baseline health characteristics (age, sex, smoking status, educational level, physical activity level, obesity, depression, and diabetes), severe periodontitis by either definition was significantly associated with MCI (for the EWP definition: adjusted OR = 3.58, 95% confidence interval [CI] = 1.45-8.87; for the CDC/AAP definition: adjusted OR = 2.61, 95% CI = 1.08-6.28). Periodontal inflammation assessed by PISA was also significantly associated with a higher OR for MCI (adjusted OR = 1.05, 95% CI = 1.01-1.10, per 10-mm2 increase in PISA). CONCLUSION: Severe periodontitis and periodontal inflammation were associated with incident MCI among older community-dwelling men and women.

    DOI: 10.1111/jre.12623

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  • Periodontitis, periodontal inflammation, and mild cognitive impairment: A 5-year cohort study. 査読 国際誌

    Masanori Iwasaki, Yumi Kimura, Hiroshi Ogawa, Takayuki Yamaga, Toshihiro Ansai, Taizo Wada, Ryota Sakamoto, Yasuko Ishimoto, Michiko Fujisawa, Kiyohito Okumiya, Hideo Miyazaki, Kozo Matsubayashi

    Journal of periodontal research   54 ( 3 )   233 - 240   2019年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND AND OBJECTIVES: Identification of modifiable factors for mild cognitive impairment (MCI) is important since individuals with MCI are at a high risk of dementia and disability. Previous studies have suggested a potential association between periodontitis and cognitive impairment, but the results remain inconclusive. We designed a 5-year longitudinal study to explore the association between MCI and periodontitis and periodontal inflammation in older adults. METHODS: This study included 179 community-dwelling dentate individuals (62 men and 117 women, average age: 80.1 years). A full-mouth periodontal examination at six sites per tooth was performed at baseline. Case definitions provided by the European Workshop in Periodontology Group C (EWP definition) and the Centers for Disease Control/American Academy of Periodontology (CDC/AAP definition) were used to define severe periodontitis. Additionally, the periodontal inflamed surface area (PISA), reflecting the amount of inflamed periodontal tissue, was calculated using clinical periodontal parameters. Follow-up cognitive examinations for MCI diagnosis were performed by neurologists 1, 2, 3, and 5 years after baseline. Odds ratios (ORs) for MCI according to the presence of periodontitis and periodontal inflammation at baseline were calculated using multilevel mixed-effects logistic regression. RESULTS: At baseline, 56.4% and 27.4% of the participants had severe periodontitis by the EWP and CDC/AAP definitions, respectively. After adjusting for follow-up period and other baseline health characteristics (age, sex, smoking status, educational level, physical activity level, obesity, depression, and diabetes), severe periodontitis by either definition was significantly associated with MCI (for the EWP definition: adjusted OR = 3.58, 95% confidence interval [CI] = 1.45-8.87; for the CDC/AAP definition: adjusted OR = 2.61, 95% CI = 1.08-6.28). Periodontal inflammation assessed by PISA was also significantly associated with a higher OR for MCI (adjusted OR = 1.05, 95% CI = 1.01-1.10, per 10-mm2 increase in PISA). CONCLUSION: Severe periodontitis and periodontal inflammation were associated with incident MCI among older community-dwelling men and women.

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  • 動脈硬化と歯周病との関連 地域在住高齢者を対象とした横断研究

    佐藤 美寿々, 岩崎 正則, 皆川 久美子, 山賀 孝之, 小川 祐司

    口腔衛生学会雑誌   69 ( 増刊 )   164 - 164   2019年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • Influence of occlusal deterioration considering prosthetics on subsequent all-cause mortality in a Japanese elderly independent population 査読

    Yamaga T, Ogawa H, Miyazaki H

    Gerodontology   36   163 - 170   2019年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Relationships between changes in posterior occlusal support and risk of protein-energy malnutrition among the Japanese community dwelling elderly 査読

    Nonomura A, Nohno K, Ogawa H

    Dentistry   9 ( 2 )   1 - 7   2019年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Effect of powdered green tea matcha on biofilm formation by mutans streptococci 査読

    Rizal MF, Kaneko N, Ogawa H

    Stoma Edu J   5   220 - 226   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Managing our older population: the challenges ahead 査読

    J.H. Meurman, G. McKenna, H. Murtomaa, M. Nakao, H. Ogawa, A. Walls, D. Williams

    J Dent Res   97 ( 10 )   1077 - 1078   2018年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • WHO Global Consultation on Public Health Intervention against Early Childhood Caries 査読

    Prathip Phantumvanit, Yuka Makino, Hiroshi Ogawa, Andrew Rugg-Gunn, Paula Moynihan, Poul Erik Petersen, Wendell Evans, Carlos Alberto Feldens, Edward Lo, Mohammad H. Khoshnevisan, Ramon Baez, Benoit Varenne, Tippanart Vichayanrat, Yupin Songpaisan, Margaret Woodward, Siriruk Nakornchai, Chantana Ungchusak

    Community Dentistry and Oral Epidemiology   46 ( 3 )   280 - 287   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Blackwell Munksgaard  

    Early Childhood Caries (ECC) is prevalent around the world, but in particular the disease is growing rapidly in low- and middle-income countries in parallel with changing diet and lifestyles. In many countries, ECC is often left untreated, a condition which leads to pain and adversely affects general health, growth and development, and quality of life of children, their families and their communities. Importantly, ECC is also a global public health burden, medically, socially and economically. In many countries, a substantial number of children require general anaesthesia for the treatment of caries in their primary teeth (usually extractions), and this has considerable cost and social implications. A WHO Global Consultation with oral health experts on “Public Health Intervention against Early Childhood Caries” was held on 26-28 January 2016 in Bangkok (Thailand) to identify public health solutions and to highlight their applicability to low- and middle-income countries. After a 3-day consultation, participants agreed on specific recommendations for further action. National health authorities should develop strategies and implement interventions aimed at preventing and controlling ECC. These should align with existing international initiatives such as the Sixtieth World Health Assembly Resolution WHA 60.17 Oral health: action plan for promotion and integrated disease prevention, WHO Guideline on Sugars and WHO breastfeeding recommendation. ECC prevention and control interventions should be integrated into existing primary healthcare systems. WHO public health principles must be considered when tackling the effect of social determinants in ECC. Initiatives aimed at modifying behaviour should focus on families and communities. The involvement of communities in health promotion, and population-directed and individual fluoride administration for the prevention and control of ECC is essential. Surveillance and research, including cost-effectiveness studies, should be conducted to evaluate interventions aimed at preventing ECC in different population groups.

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  • Hyposalivation and 10-year all-cause mortality in an elderly Japanese population 査読

    Masanori Iwasaki, Wenche S. Borgnakke, Akihiro Yoshihara, Kayoko Ito, Hiroshi Ogawa, Kaname Nohno, Misuzu Sato, Kumiko Minagawa, Toshihiro Ansai, Hideo Miyazaki

    Gerodontology   35 ( 2 )   87 - 94   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Blackwell Munksgaard  

    Objective: To evaluate the association of salivary flow rate with all-cause mortality among older Japanese adults. We hypothesised that hyposalivation would be a marker for mortality. Background: Hyposalivation, which is an objectively measurable decrease in salivary flow, is highly prevalent among older adults. It is associated with malnutrition and poor general health. Methods: The study population comprised 600 community-dwelling Japanese adults (306 men and 294 women), who were 70 years old at baseline. They underwent stimulated salivary flow rate (SSFR) measurements and were followed up during a 10-year study period. After stratification by sex, the hazard ratios of all-cause mortality were estimated using Cox proportional hazards regression analysis comparing groups with and without hyposalivation (ie, SSFR &lt
     0.7 mL/min). Results: The baseline prevalence of hyposalivation was 27.8% (85/306) among men and 47.3% (139/294) among women. During a mean (standard deviation) follow-up period of 104 (27) months, 80 deaths occurred: 60 (75.0%) deaths among men and 20 (25.0%) deaths among women. After adjusting for the number of remaining teeth, smoking status, exercise, hypoalbuminemia, diabetes and cardiovascular disease, hyposalivation at baseline was significantly associated with all-cause mortality among men (adjusted hazard ratio, 1.71
    95% confidence interval, 1.01-2.89). In contrast, no association between SSFR and all-cause mortality existed among women. Conclusion: Hyposalivation could be a marker for all-cause mortality among older community-dwelling Japanese men. Future studies investigating the association between SSFR and cause-specific mortality are warranted.

    DOI: 10.1111/ger.12319

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  • Effect of lifestyle on 6-year periodontitis incidence or progression and tooth loss in older adults. 査読 国際誌

    Iwasaki M, Borgnakke WS, Ogawa H, Yamaga T, Sato M, Minagawa K, Ansai T, Yoshihara A, Miyazaki H

    Journal of clinical periodontology   45 ( 8 )   896 - 908   2018年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jcpe.12920

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  • 高次生活機能の加齢に伴う変化の軌跡と歯の本数の関連についての縦断研究

    岩崎 正則, 佐藤 美寿々, 皆川 久美子, 安細 敏弘, 葭原 明弘, 小川 祐司, 宮崎 秀夫

    口腔衛生学会雑誌   68 ( 増刊 )   112 - 112   2018年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • Association between serum resistin level and periodontal condition change among elderly people 査読

    Ogawa H, Damrongrungruang T, Furugen R, Hayashida H, Saito T, Yoshihara A, Miyazaki H

    Stoma Edu J   5 ( 1 )   24 - 30   2018年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Implications of WHO Guideline on Sugars for dental health professionals 査読

    Paula Moynihan, Yuka Makino, Poul Erik Petersen, Hiroshi Ogawa

    Community Dentistry and Oral Epidemiology   46 ( 1 )   1 - 7   2018年2月

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    記述言語:英語   出版者・発行元:Blackwell Munksgaard  

    The burden of oral disease is high in populations across the world. This is because of high consumption of free sugars. The WHO Guideline on Sugars Intake for Adults and Children recommended limiting free sugars to no more than 5% energy intake to protect oral health throughout the life-course. The objectives of this paper are to consider the implications of the Guideline for dental health practice and to advocate use of the common risk factor approach when providing dietary advice. As part of a broad range of actions needed to reduce free sugars intake, improved education for dental health professionals and supporting patients to eat less free sugars are key actions for the dental profession. All dental health professionals should have the skills and confidence to provide their patients with healthier eating advice, including how to limit free sugars intake. It is therefore important that dental health professionals receive adequate education in diet and nutrition, and there is a need for dental educational regulating bodies to define the content of the dental curriculum with respect to nutrition. All patients, or their parents or carers, should receive dietary advice to reduce free sugars within the context of a healthy diet for the prevention of all NCDs. Dietary advice should: (i) focus on reducing the amount of free sugars consumed
    (ii) be tailored according to the patient's body mass status (eg underweight, overweight, normal weight)
    (iii) encourage the consumption of fresh fruits and vegetables, nuts, seeds, and wholegrain starch-rich foods
    (iv) discourage the consumption of foods high in saturated fat and salt
    and (v) discourage the consumption of all drinks containing free sugars. The dental health professional has an opportunity to support patients to reduce their intake of free sugars—such advice and support will have positive impacts beyond the mouth.

    DOI: 10.1111/cdoe.12353

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  • Promoting oral health and quality of life of older people - The need for public health action 査読

    Poul Erik Petersen, Hiroshi Ogawa

    Oral Health and Preventive Dentistry   16 ( 2 )   113 - 124   2018年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Quintessence Publishing Co., Ltd  

    Purpose: This report intends to review the global burden of oral disease among older people and to examine their oral health needs. The evidence on the inter-relationships between poor oral health conditions of older people, general health and quality of life is highlighted. Finally, WHO strategies to improve oral health of older people are reviewed. Methods: The information relevant to this review was extracted from the WHO Global Oral Health Data Bank, the PubMed database, and the Cochrane Library. Surveys were carried out according to the criteria recommended by the WHO epidemiological manual Oral Health Surveys - Basic Methods. In addition, global data were sought on coverage of oral health care among older people. Finally, WHO policy documents on health care for aged people were gathered through the WHO website. Results: Across the globe, many older people suffer from oral pain or discomfort. Poor oral health during old age is mostly manifest in high caries experience, high prevalence rates of advanced periodontal disease, severe tooth loss, dry mouth, and oral pre-cancer/cancer. In both developing and developed countries, the burden of disease is particularly high among underprivileged and disadvantaged older people. In numerous countries, high proportions of the aged population are not covered by primary oral health care
    this is mainly the case in low and middle income countries due to a critical shortage of dentists. Conclusions: In 2015, the WHO published the World Report on Ageing and Health, which outlines a framework for action to foster healthy ageing. The policies are highly relevant to the improvement of oral health. Transformation of oral health systems away from a disease-based curative model and towards disease prevention, as well as the provision of older-person-centred integrated care are required. Moreover, wide-ranging public health action on ageing is urgently needed.

    DOI: 10.3290/j.ohpd.a40309

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  • 地域在住高齢者における現在歯数および義歯の使用状況・主観的評価とフレイルとの関連についての横断研究 査読

    佐藤美寿々, 岩崎正則, 皆川久美子, 小川祐司, 山賀孝之, 葭原明弘, 宮崎秀夫

    口腔衛生会誌   68   68 - 75   2018年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  • Oral health for healthy longevity in an ageing society: maintaining momentum and moving forward 査読

    Kakuhiro Fukai, Hiroshi Ogawa, Patrick Hescot

    INTERNATIONAL DENTAL JOURNAL   67   3 - 6   2017年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY  

    The ageing of populations worldwide is rapidly accelerating. However, the global burden of oral disease remains a critical and often underestimated problem. As ageing progresses globally, oral health maintenance becomes a matter not only of public health, but also of human rights. Therefore, in low- and middle-income countries, policymakers are seeking to realize universal health coverage even as they struggle with severe resource limitations. To achieve and maintain global oral health, we propose an ongoing global monitoring cycle consisting of the following four steps: needs assessment, implementation of appropriate health care systems and provisions, reducing the global burden of oral disease, and working to achieve a healthy ageing society. Rather than a unidirectional information flow from high income to low- and middle-income countries, the proposed system would establish a multidirectional information-sharing cycle that would benefit all countries. To make this possible, however, we must develop a standardized set of core oral health indicators that all countries use, as well as a global repository for gathering, compiling, and sharing the data. This system would allow each country to move forward at its own pace and in locally-appropriate ways, making it more effective and efficient in the long run than the current pattern of setting unrealistic goals that all countries are expected to achieve by a certain point in time.

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  • 現在歯数20本以上の75歳高齢者は「健康な食事パターン」を満たしているか? 査読

    木村秀喜, 渡邊智子, 鈴木亜夕帆, 岩崎正則, 葭原明弘, 小川祐司, 宮﨑秀夫

    口腔衛生会誌   67 ( 3 )   172 - 180   2017年7月

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  • Strategy for Oral Disease Prevention and Health Promotion -WHO perspective - 査読

    Ogawa H

    Int J Oral Health   13   41 - 45   2017年6月

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    記述言語:英語   掲載種別:研究論文(国際会議プロシーディングス)  

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  • フィリピン国マンダウエ市における小児の公私立学校就学による齲蝕有病、成長発育および食習慣の違いとそれらの相互関連

    西川 敦子, 山賀 孝之, 小川 祐司, 宮崎 秀夫

    新潟歯学会雑誌   47 ( 1 )   23 - 32   2017年6月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

    本研究は、フィリピン国マンダウエ市において学童の公立あるいは私立学校就学という社会的属性による齲蝕有病状況、成長発育、口腔保健状況および食習慣の差異を調べ、さらにそれら相互の関連を検討することを目的とした。公立学校就学(公立群)の6歳児41名、12歳児42名、私立学校就学(私立群)の6歳児47名、12歳児50名を対象とした。6歳児のdf者率、12歳児のDMF者率はいずれも公立群の方が有意に高かったが、私立群も先進国と比較すれば決して良好な齲蝕有病状況とはいえなかった。身長は私立群の方が有意に高く、歯の交換状況も加味すると公立群は成長発育遅延の可能性が示唆された。さらに、公立群は低体重児が多く、対照的に私立群は肥満傾向があった。また、公立群の児童およびその保護者は口腔保健に対する意識や知識量が私立群よりも低く、その差は保護者の方がより大きかった。各項目と齲蝕有病状況との関連は6歳児ではdft、df者率ともに保護者の歯科的な訴えの有無および歯科受療の有無との有意な関連が認められた。12歳児では保護者の学歴と齲蝕有病状況に有意な関連があった。以上より学童の公立あるいは私立学校就学という社会的属性の間に保護者の学歴、教育環境などに関する様々な社会的格差が存在し、これらが要因となって児童の齲蝕有病状況、受療行動および健康意識に影響を及ぼしている可能性が示唆された。(著者抄録)

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  • The assessment of status of tobacco smoking among urban primary schoolchildren in Madagascar 査読

    Noeline Razanamihaja, Yuka Makino, Hiroshi Ogawa, Noriaki Ikeda, Hideo Miyazaki

    HEALTH PROMOTION INTERNATIONAL   32 ( 2 )   351 - 359   2017年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:OXFORD UNIV PRESS  

    The prevalence of tobacco smoking among adolescents aged 13-15 years old in Madagascar was previously reported to be higher than the average in other African regions. A preventive approach is urgently needed to avoid the initiation of early tobacco smoking. Therefore, the aims of this study were to evaluate the status of tobacco smoking among primary schoolchildren in Madagascar and explore the factors associated with initiation of tobacco smoking in the young. This study was conducted in the Mahajanga region of Madagascar. Three primary schools in this region and children of both genders between the ages of nine to 12 years old were randomly selected and approached to participate in this study. A self-administered questionnaire modified from the Global Youth Tobacco Survey Core Questionnaire 2007 was used to assess the status of tobacco smoking among primary schoolchildren. A total of 150 schoolchildren (14.0%) declared that they had smoked tobacco, with 30% starting to smoke tobacco at the age of seven or younger. The prevalence of tobacco smoking was lower among schoolchildren with non-smoking parents (p &lt; 0.001) or non-smoking close friends (p &lt; 0.001). Furthermore, schoolchildren's antismoking intention (p &lt; 0.001) and their knowledge about the harmfulness of tobacco (p = 0.009) had significant effects on the prevalence of tobacco smoking. The results of this study indicate that tobacco smoking among schoolchildren in Madagascar may be influenced by peers, or parents, as well as smoking intention and knowledge about the harmfulness of tobacco use.

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  • The association between dentition status and sarcopenia in Japanese adults aged ≥75 years 査読

    M. Iwasaki, M. Iwasaki, Y. Kimura, H. Ogawa, T. Wada, R. Sakamoto, Y. Ishimoto, M. Fujisawa, K. Okumiya, T. Ansai, H. Miyazaki, K. Matsubayashi

    Journal of Oral Rehabilitation   44 ( 1 )   51 - 58   2017年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    © 2016 John Wiley &amp; Sons Ltd Sarcopenia is an age-related loss of muscle mass and muscle strength or physical performance. There are limited data on the association between oral health and sarcopenia. To test the hypothesis that impaired dentition status was associated with sarcopenia, we conducted a cross-sectional study. A total of 272 community-dwelling Japanese adults aged ≥75 years for whom data were available from comprehensive health examinations conducted in 2015 were included in this study. During dental examination, the number of natural teeth and occluding pairs of natural teeth was counted. In denture wearers, the fit of the removable dentures was also evaluated. The criteria proposed by the Asian Working Group for Sarcopenia were used to define sarcopenia. A multivariable logistic regression model was used to evaluate the association between dentition status and the presence of sarcopenia. The prevalence of sarcopenia was 25·7% (70/272). Compared to individuals with ≥10 occluding pairs of natural teeth, those with no occluding pairs of natural teeth had significantly higher risk of having sarcopenia (adjusted odds ratio, 3·37; 95% confidence interval, 1·07–10·61), after adjusting for possible confounders. In addition, compared to individuals with well-fitting dentures, those with ill-fitting dentures had significantly higher risk of having sarcopenia (adjusted odds ratio, 5·07; 95% confidence interval, 1·59–16·19). Our findings suggest that impaired dentition status is significantly associated with sarcopenia among community-dwelling Japanese adults aged ≥75 years. Future longitudinal studies with larger, more diverse populations are necessary to validate our findings.

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  • Longitudinal association of dentition status with dietary intake in Japanese adults aged 75 to 80 years 査読

    M. Iwasaki, A. Yoshihara, H. Ogawa, M. Sato, K. Muramatsu, R. Watanabe, T. Ansai, H. Miyazaki

    JOURNAL OF ORAL REHABILITATION   43 ( 10 )   737 - 744   2016年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    Limited information is available on the temporal association between dentition status and dietary intake. The aim of this 5-year prospective cohort study was to investigate whether impaired dentition was associated with subsequent decline in dietary intake in older Japanese adults. Two hundred and eighty-six community-dwelling Japanese individuals, all aged 75 years at baseline, were included in the study. Functional tooth units (FTUs), defined as a pair of opposing natural or prosthetic teeth excluding third molars (range: 0-14), were counted on the basis of baseline dental examinations. Individuals with 5 FTUs were defined as having impaired dentition. Dietary intake was assessed at baseline and 5 years later, using a validated dietary questionnaire. Robust regression analyses were used to evaluate the differences in change in dietary intake between participants with and without impaired functional dentition, after adjustment for potential confounders. Sixty-one study participants (213 %) were defined as having impaired dentition. Overall, mean values for all estimated dietary variables (energy, nutrients and food groups) declined over time. Notably, individuals with impaired dentition demonstrated a significantly (P &lt; 005) greater degree of decline in the intake of multiple nutrients (protein, sodium, potassium, calcium, vitamin A, vitamin E and dietary fibre) and food groups (vegetable and meat) than those without impaired dentition, after adjusting for potential confounders. The results of this study describe the temporal association of impaired dentition with the decline in selected nutrient and food group intake among older Japanese adults.

    DOI: 10.1111/joor.12427

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  • フィリピン共和国マンダウエ市における社会経済状況別にみた学童の齲蝕罹患状況、口腔衛生習慣、身体発育状況および食生活状況 査読

    西川 敦子, 山賀 孝之, 小川 祐司, 宮崎 秀夫

    新潟歯学会雑誌   46 ( 1 )   49 - 50   2016年7月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

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  • Prevention of dental caries through the use of fluoride - the WHO approach 査読

    Poul Erik Petersen, Hiroshi Ogawa

    COMMUNITY DENTAL HEALTH   33 ( 2 )   66 - 68   2016年6月

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    記述言語:英語   出版者・発行元:F D I WORLD DENTAL PRESS LTD  

    DOI: 10.1922/CDH_Petersen03

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  • Long term evaluation of the clinical effectiveness of community milk fluoridation in Bulgaria 査読

    P. E. Petersen, S. Kwan, H. Ogawa

    COMMUNITY DENTAL HEALTH   32 ( 4 )   199 - 203   2015年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:F D I WORLD DENTAL PRESS LTD  

    To determine the clinical effectiveness of a community milk fluoridation programme. Basic research design: Parallel arm 5-year cohort study, with final cross-sectional comparisons between groups. Participants: 3-year-olds in 8 Bulgarian cities/towns entered the cohort study with random samples (n=1,782) recruited at baseline in 2004. After 5 years in 2009 sub-samples (about 30%) of these now aged 8 were randomly selected in intervention sites for follow-up examination (n=454); 276 controls were examined at the age 8 years. For cross-sectional comparisons, in 2004, 284 3-year-olds from control cities were baseline examined for caries, then 276 children at the age 8 years in 2009. Interventions: In six intervention communities: 1,498 examined children received 0.5mg F in 100 or 200ml school milk or yogurt provided each school day; a further 180 received non-fluoridated milk. In two control communities, fluoride was not added to 284 children's school milk. Main outcome measures: Dental caries experience of primary, and permanent teeth. Results: For primary teeth, caries increments were 46% (p&lt;0.001) and 30% (p&lt;0.01) lower in the fluoridated milk groups compared with non-fluoridated milk groups in the intervention and control communities, respectively. For permanent teeth those reductions were 61% and 53% (p&lt;0.001). The cross-sectional comparisons of 8-year-olds showed significant changes in dental caries experience over time; in children consuming fluoridated milk the level of dmfs fell by 43% (2004 and 2009) against 11% in the control group. Among children consuming fluoridated milk the DMFS fell 68% against rising 3% in the controls. Conclusions: Fluoridated milk delivered daily in schools in Bulgaria resulted in substantially lower caries development compared with children in schools receiving milk without added fluoride. The nation-wide experiences from milk fluoridation indicate that such a public health scheme can be effective to the global fight against dental caries of children.

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  • Oral health status in relation to cognitive function among older Japanese. 査読 国際誌

    Masanori Iwasaki, Yumi Kimura, Akihiro Yoshihara, Hiroshi Ogawa, Takayuki Yamaga, Misuzu Sato, Taizo Wada, Ryota Sakamoto, Yasuko Ishimoto, Eriko Fukutomi, Wenling Chen, Hissei Imai, Michiko Fujisawa, Kiyohito Okumiya, George W Taylor, Toshihiro Ansai, Hideo Miyazaki, Kozo Matsubayashi

    Clinical and experimental dental research   1 ( 1 )   3 - 9   2015年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Epidemiologic data examining the relationship between oral health status and cognitive status are sparse, especially in Asian populations. This study aimed to assess whether periodontal disease and tooth loss were related to cognitive impairment among older Japanese. Study participants were 291 Japanese (101 men and 190 women, average age: 80.9 years), classified into three groups based on a clinical examination of oral health status: no periodontal disease, periodontal disease, and edentulous. Periodontal disease was defined using criteria recommended in the consensus report of the European Workshop in Periodontology with a modification. Cognitive impairment was defined using the results of the Mini-mental State Examination (MMSE) and Hasegawa Dementia Scale-Revised (HDS-R) scores. Multivariable logistic regression analyses assessed the relationship of the three-category oral health status variable (reference category = no periodontal disease) with low MMSE score (≤23) and low HDS-R score (≤20). Age, gender, years of education, body mass index, smoking status, drinking behavior, and history of cardiovascular disease were tested as potential confounders in the multivariable models. Periodontal disease and edentulous were significantly associated with greater odds of low cognitive performance after controlling for potential confounders. The multivariable adjusted odds ratios (ORs) (95% confidence intervals [CIs]) for low MMSE score associated with periodontal disease and edentulous were 2.21 (1.01-4.84) and 2.28 (1.06-4.90), respectively. The multivariable adjusted ORs (95% CIs) for low HDS-R score associated with periodontal disease and edentulous were 4.85 (1.29-18.15) and 3.86 (1.05-14.20), respectively. Poor oral health status was significantly associated with cognitive impairment among community-dwelling older Japanese. Additional well-controlled longitudinal studies are needed to elucidate whether there may be a possible cause-and-effect relationship between oral health status and cognitive function.

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  • Number of teeth and 5-year mortality in an elderly population 査読

    Toshinobu Hirotomi, Akihiro Yoshihara, Hiroshi Ogawa, Hideo Miyazaki

    COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY   43 ( 3 )   226 - 231   2015年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    ObjectivesSeveral epidemiological studies have shown the association between tooth loss and mortality. However, the impact of number of teeth on mortality has not yet been fully addressed in an elderly population with many teeth. Thus, the purpose of this cohort study was to assess the possible role of number of teeth as a predictor of mortality in the elderly.
    MethodsThe subjects included in this study were generated from a cohort study started in 1998. Oral examinations and the completion of a questionnaire were carried out. A total of 600 subjects aged 70years were enrolled at baseline. All the subjects were in good general health and did not require any special care for their daily activities. The 5-year mortality data were collected after the baseline survey. After excluding those with incomplete data, 569 subjects were analyzed. The Kaplan-Meier method was used to analyze survival curves and a Cox regression model to clarify the impact of the number of remaining teeth on the 5-year mortality.
    ResultsDuring the follow-up period, 25 (4.4%) subjects died. Subjects with 20 teeth or more had a significantly lower mortality rate (2.5%) than those with 19 teeth or fewer (6.1%, log-rank test, P=0.036). Even after adjusting for confounders including gender, BMI, serum albumin level, current smoking status, education, number of family members living together and a history of chronic diseases, the risk of all-cause mortality was significantly associated with the number of remaining teeth (P=0.047) with a hazard ratio of 0.96, indicating that there was a 4% point increase in the 5-year survival rate per additional tooth retained at the age of 70.
    ConclusionThe findings of this study suggest that retaining more teeth might be a useful indicator for longevity of older people.

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  • Association between dental status and food diversity among older Japanese 査読

    M. Iwasaki, Y. Kimura, A. Yoshihara, H. Ogawa, T. Yamaga, T. Takiguchi, T. Wada, R. Sakamoto, Y. Ishimoto, E. Fukutomi, W. Chen, H. Imai, M. Fujisawa, K. Okumiya, M. C. Manz, H. Miyazaki, K. Matsubayashi

    COMMUNITY DENTAL HEALTH   32 ( 2 )   104 - 110   2015年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:F D I WORLD DENTAL PRESS LTD  

    Objective: To investigate the relationship of dental status to food diversity among older Japanese. Design and Setting: A community-based cross-sectional study conducted in the town of Tosa, Kochi Prefecture, Japan. Methods: The study participants were 252 Japanese ( 84 men and 168 women, average age 81.2 years) and dentate participants were classified into three groups: 1-9 teeth, 10-19 teeth and 20 or more teeth. Food diversity was assessed as a validated measure of dietary quality using the 11-item Food Diversity Score Kyoto (FDSK-11), which evaluates frequency of consumption of 11 main food groups. Multivariable analysis of the differences in FDSK-11 score ranging from 0 to 11, with a higher score indicating greater food diversity, among the three dental status groups was conducted using general linear models. All the performed analyses were stratified by gender. Results: There was no association between dental status and food diversity score in models for men. In contrast, women with &lt;= 9 teeth and with 10-19 teeth had significantly lower FDSK-11 scores than women with &gt;= 20 teeth after adjusting for confounders (p&lt;0.001 and p=0.009, respectively). Additionally, there was a trend toward lower scores for FDSK-11 with fewer teeth (p=0.001). Conclusion: A less varied diet, as indicated by low FDSK-11 score, was observed in female participants with fewer teeth. Tooth loss was associated with poor diet quality among older Japanese women.

    DOI: 10.1922/CDH_3502Iwasaki07

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  • Correlation between SNP genotypes and periodontitis in Japanese type II diabetic patients: a preliminary study 査読

    Teerasak Damrongrungruang, Hiroshi Ogawa, Sayaka Hori-Matsumoto, Kumiko Minagawa, Osamu Hanyu, Hirohito Sone, Hideo Miyazaki

    ODONTOLOGY   103 ( 2 )   233 - 240   2015年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SPRINGER  

    The present study aims to investigate the correlation between SNP genotype patterns and periodontitis severity in Japanese type II diabetic patients. A cross-sectional study in 43 Japanese diabetic patients with periodontitis was performed. Blood samples were drawn for single nucleotide polymorphism (SNP) analyses and periodontal index (probing pocket depth and clinical attachment level) was subsequently recorded. Twelve functional genes with SNPs that had been shown to be associated with diabetes and/or inflammation were genotyped using a nuclease-mediated SNP-specific ligation method. Subjects with two or more sites with clinical attachment level a parts per thousand yen6 mm and who additionally had one or more sites with pocket depth a parts per thousand yen5 mm were classified as having severe periodontitis. Proportions of risk genotypes/non-risk genotypes between severe and non-severe periodontitis were subsequently compared. A high frequency (21/43 participants, 49 %) of adiponectin gene polymorphism (ADIPOQ 45T &gt; G) homozygous risk genotype (TT genotype) was observed in the participants. The frequency of TGF-beta 1 SNP (29C &gt; T) risk genotype (TT genotype) in severe periodontitis (34 %, n = 11) was significantly higher than in non-severe periodontitis (0 %, n = 0) (p = 0.04). Our study suggests that TGF-beta 1 SNPs (29C &gt; T) may be used as one of the risk indicators for severe periodontitis in Japanese diabetic patients.

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  • 地域在住高齢者における歯・口腔の健康が認知機能検査スコアに与える影響 査読

    岩崎 正則, 葭原 明弘, 小川 祐司, 山賀 孝之, 佐藤 美寿々, 安細 敏弘, 宮崎 秀夫

    口腔衛生学会雑誌   65 ( 2 )   195 - 195   2015年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • Relationship between metabolic syndrome and periodontitis in 80-year-old Japanese subjects 査読

    K. Minagawa, M. Iwasaki, H. Ogawa, A. Yoshihara, H. Miyazaki

    JOURNAL OF PERIODONTAL RESEARCH   50 ( 2 )   173 - 179   2015年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY  

    Background and ObjectivePotentially significant associations between metabolic syndrome (MetS) and periodontitis have been reported in recent studies; however, there are limited data on their association in the very old. The aim of this cross-sectional study was to investigate the association between MetS and periodontitis among 80-year-old Japanese subjects.
    Material and MethodsThe subjects were 234 Japanese aged 80years old who participated in a health and periodontal examination in June 2008 in Niigata city, Japan, and were classified into three groups: (i) severe periodontitis: having six or more interproximal sites with clinical attachment level 6mm and three or more interproximal sites with probing pocket depth (PPD) 5mm (not on the same tooth) (n=19); (ii) moderate periodontitis: having six or more interproximal sites with clinical attachment level 4mm or six or more interproximal sites with PPD 5mm (not on the same tooth) (n=162); and (iii) no or mild periodontitis: neither moderate nor severe periodontitis (n=53). MetS was defined using the modified criteria of the guidelines for the diagnosis of MetS in Japan. An ordinal logistic regression model was used to evaluate the association between MetS and periodontitis. Adjustments for gender, income, education, smoking status, dental visiting patterns, brushing frequency, exercise habits and dietary energy and food intake were considered.
    ResultsOverall, 57 individuals (24.4%) were diagnosed as having MetS. MetS was associated with the presence and severity of periodontitis (crude odds ratio=2.24, 95% confidence interval=1.14-4.41). This association remained statistically significant after multivariate adjustments (adjusted odds ratio=2.10, 95% confidence interval=1.03-4.28).
    ConclusionOur findings provide evidence of an association between MetS and periodontitis in elderly Japanese.

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  • Education on tobacco use interventions for undergraduate dental students 査読

    Takashi Hanioka, Miki Ojima, Yoko Kawaguchi, Yukio Hirata, Hiroshi Ogawa, Daisuke Hinode, Nobuhiro Hanada, Eiji Inoshita

    Japanese Dental Science Review   51 ( 3 )   65 - 74   2015年

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    記述言語:英語   出版者・発行元:Elsevier Ltd  

    Inadequate training for dental professionals hampers the implementation of tobacco use interventions for the improvement of dental practice and oral and overall health. To improve dental education regarding tobacco use prevention and cessation (DENTUPAC), we examined literature addressing previous efforts and experiences with this goal. The majority of studies, published in the US and Europe, reported that a transition from didactic to clinical education achieved moderate-level interventions. The need for a comprehensive multidisciplinary approach and the low confidence of faculty members in their own ability to effectively teach DENTUPAC are commonly reported barriers to DENTUPAC in clinical settings. Objective structured clinical examinations of standardized patients and motivational interviewing have proven consistently successful in DENTUPAC and are included in faculty development workshops and internet-based training. However, levels of intervention from dentists on quitting smoking reported by their patients were relatively low compared to those from physicians, although most dentists reported that they counsel patients. In addition to previous efforts and experiences in developing and disseminating DENTUPAC, the optimization of DENTUPAC by evaluating education on health behavior interventions may help increase the involvement of dentists in cessation counseling upon graduation.

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  • Low dietary diversity among older Japanese adults with impaired dentition 査読

    Iwasaki M, Kimura Y, Yoshihara A, Ogawa H, Yamaga T, Wada T, Sakamoto R, Ishimoto Y, Fukutomi E, Vhen WL, Imai H, Fujisawa M, Okumiya K, Manz MC, Ansai T, Miyazaki H, Matsubayashi K

    Journal of Dentistry and Oral Hygiene   7 ( 4 )   40 - 43   2015年

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    記述言語:英語  

    DOI: 10.5897/JDOH2014.0142.

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  • Effect of periodontal treatment on adipokines in type 2 diabetes. 査読 国際誌

    Ogawa H, Damrongrungruang T, Hori S, Nouno K, Minagawa K, Sato M, Miyazaki H

    World journal of diabetes   5 ( 6 )   924 - 931   2014年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.4239/wjd.v5.i6.924

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  • Serum albumin levels and 10-year tooth loss in a 70-year-old population 査読

    A. Yoshihara, M. Iwasaki, H. Ogawa, H. Miyazaki

    JOURNAL OF ORAL REHABILITATION   40 ( 9 )   678 - 685   2013年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    Serum albumin levels are a practical marker of general health status in the elderly and have been used to determine the severity of underlying diseases and the risk for death. This longitudinal study evaluated the relationship between serum albumin concentrations and tooth loss over 10years in elderly subjects, after controlling for confounding factors. A sample of 554 dentate subjects among enrolled subjects (n=600) was involved in this planned longitudinal study with follow-up examinations after 5 and 10years. At the 5-year follow-up, 373 (673%), subjects were available for re-examination. In addition, 331 (597%) were available at the 10-year follow-up. Multiple Poisson regression analysis was conducted to evaluate the relationship between the number of missing teeth over 5 or 10years and serum albumin levels at baseline after adjusting for 10 variables: gender, serum markers levels at baseline, dental status, smoking habits and educational years and oral health behaviour. The number of missing teeth over 5 or 10years was significantly negatively associated with serum albumin levels at baseline [incidence rate ratios (IRR)=0373, P&lt;00001 for 5years; IRR=0570, P&lt;00001 for 10years]. We conclude that elderly subjects with hypoalbuminemia are at high risk for 5- and 10-year tooth loss.

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  • Evaluation of chewing ability and its relationship with activities of daily living, depression, cognitive status and food intake in the community-dwelling elderly 査読

    Yumi Kimura, Hiroshi Ogawa, Akihiro Yoshihara, Takayuki Yamaga, Tomoya Takiguchi, Taizo Wada, Ryota Sakamoto, Yasuko Ishimoto, Eriko Fukutomi, Wenling Chen, Michiko Fujisawa, Kiyohito Okumiya, Kuniaki Otsuka, Hideo Miyazaki, Kozo Matsubayashi

    GERIATRICS & GERONTOLOGY INTERNATIONAL   13 ( 3 )   718 - 725   2013年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    Aim: The aim of this study was to assess chewing ability using color-changeable chewing gum and to show the association between chewing ability and geriatric functions, as well as dietary status in the community-dwelling elderly.
    Methods: The study population consisted of 269 community-dwelling elderly aged &gt;= 75 living in Tosa, Japan. Assessment of chewing ability was carried out by a dentist using color-changeable chewing gum. Activities of daily living (ADL), depression and subjective quality of life (QOL) were assessed by questionnaire. Cognitive status was assessed by; Mini-Mental State Examination (MMSE), Hasegawa Dementia Scale-Revised (HDS-R) and Frontal Assessment Battery (FAB) during the check-up. Food diversity was assessed using the 11-item Food Diversity Score Kyoto (FDSK-11).
    Results: Number of teeth was significantly related to chewing ability (P &lt; 0.001). The participants with low chewing ability had significantly lower ADL scores in the items of self-maintenance (P = 0.029) and intellectual activity (P = 0.021). There was a significant association between low chewing ability and depression (P &lt; 0.001). Lower cognitive functions were significantly related to low chewing ability; MMSE (P = 0.022), HDSR (P = 0.017) and FAB (P = 0.002). The participants with low chewing ability had lower food variety (P &lt; 0.001), and less frequent intake of beans, vegetables, seaweed and nuts, than the participants with high chewing ability.
    Conclusion: Low chewing ability evaluated by color-changeable gum was associated with lower ADL, lower cognitive functioning, depression and food insufficiency in the community-dwelling elderly. More attention should be paid to assessing chewing ability of elderly persons in community settings. Geriatr Gerontol Int 2013; 13: 718-725.

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  • Tobacco interventions by dentists and dental hygienists 査読

    Takashi Hanioka, Miki Ojima, Yoko Kawaguchi, Yukio Hirata, Hiroshi Ogawa, Yumiko Mochizuki

    Japanese Dental Science Review   49 ( 1 )   47 - 56   2013年2月

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    記述言語:英語  

    Tobacco use is a modifiable risk factor for oral disease. Dental professionals are able to reduce the burden of oral and overall health by influencing tobacco use.Results of electronic searches for literature indicated progress in tobacco interventions in dentistry. Patients believed that dentists should routinely offer smoking cessation services, and those interested in quitting felt comfortable receiving advice about quitting. Dental professionals were aware of the importance of tobacco interventions. However, tobacco intervention practices were limited or restricted, and dental professionals have not fully embraced opportunities for tobacco intervention. A consistently reported barrier was the lack of training. Although various factors were identified as barriers and facilitators, few study assessed structure for the implementation of tobacco interventions. Tobacco-related education of undergraduate students has been recognized as an important issue. Globally, the majority of dental students recognized themselves as role models in society and believed they should receive training. However, few reported receiving such formal training.Dental researchers and educators around the world should explore new knowledge and exchange experiences to make full use of the unique opportunity of providing dental interventions against tobacco use. © 2012 Japanese Association for Dental Science.

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  • 高齢者における咀嚼能力と体力の関係について

    瀧口 知彌, 小川 祐司, 葭原 明弘, 山賀 孝之, 宮崎 秀夫

    口腔衛生学会雑誌   63 ( 1 )   44 - 44   2013年1月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • The global burden of periodontal disease: towards integration with chronic disease prevention and control 査読

    Poul E. Petersen, Hiroshi Ogawa

    PERIODONTOLOGY 2000   60 ( 1 )   15 - 39   2012年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    DOI: 10.1111/j.1600-0757.2011.00425.x

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  • Translating science into action: periodontal health through public health approaches 査読

    Nanna Juergensen, Poul E. Petersen, Hiroshi Ogawa, Sayaka Matsumoto

    PERIODONTOLOGY 2000   60 ( 1 )   173 - 187   2012年10月

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    記述言語:英語   出版者・発行元:WILEY-BLACKWELL  

    DOI: 10.1111/j.1600-0757.2012.00451.x

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  • 地域在住高齢者におけるメタボリックシンドロームと歯周病の関連

    坂入 久美子, 岩崎 正則, 小川 祐司, 葭原 明弘, 宮崎 秀夫

    新潟歯学会雑誌   42 ( 1 )   63 - 64   2012年6月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

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  • Tooth-related risk factors for tooth loss in community-dwelling elderly people 査読

    Toshinobu Hirotomi, Akihiro Yoshihara, Hiroshi Ogawa, Hideo Miyazaki

    COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY   40 ( 2 )   154 - 163   2012年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    Objectives: To appropriately explore risk factors for tooth loss operating at the tooth-level, subject-related factors and a hierarchical data structure have to be considered. The purpose of this study was to evaluate tooth-related and subject-related risk factors affecting tooth loss. Methods: A 10-year longitudinal survey was carried out on 286 elderly subjects. At baseline, the prosthodontic status and abutment function of the 5574 teeth were recorded. Tooth loss was defined as the main outcome variable, and a multilevel logistic regression model considering subject and tooth levels was applied. Results: Tooth loss was found in 75% of subjects and most frequently in molars. A multivariable, multilevel logistic regression revealed that the following tooth-related variables were significantly related to tooth loss over 10 years: maxillary teeth, multirooted teeth, single crowns, abutment teeth for a fixed/removable partial denture (FPD/RPD), and periodontally involved teeth. Among them, single crowns, abutment teeth for an FPD, and teeth with severe periodontal disease at baseline had the highest odds of 5.1, 6.0, and 7.1, respectively. Conclusion: The findings of this study suggest that tooth loss is the result of complex interactions of tooth-related factors. Several tooth-related variables including multirooted teeth, abutments, and single crowns were found to be possible risk factors for tooth loss. Thus, these findings confirm and underline the potential benefit of minimizing prosthetic treatment of molars.

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  • 地域在住高齢者におけるメタボリックシンドロームと歯周病の関連

    坂入 久美子, 岩崎 正則, 小川 祐司, 葭原 明弘, 宮崎 秀夫

    口腔衛生学会雑誌   62 ( 2 )   217 - 217   2012年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 高齢者における咀嚼能力と体力およびうつ傾向との関係について

    瀧口 知彌, 葭原 明弘, 小川 祐司, 山賀 孝之, 宮崎 秀夫

    口腔衛生学会雑誌   62 ( 1 )   64 - 64   2012年1月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • Association of dental status with vegetable intake in an elderly population 査読

    T Hirotomi, A Yoshihara, H Ogawa, H Miyazaki

    The Journal of Aging Research & Clinical Practice   1   84 - 87   2012年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Global oral health of older people - Call for public health action 査読

    P. E. Petersen, D. Kandelman, S. Arpin, H. Ogawa

    COMMUNITY DENTAL HEALTH   27 ( 4 )   257 - 267   2010年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:F D I WORLD DENTAL PRESS LTD  

    Background: The aim of this report is 1) to provide a global overview of oral health conditions in older people, use of oral health services, and self care practices; 2) to explore what types of oral health services are available to older people, and 3) to identify some major barriers to and opportunities for the establishment of oral health services and health promotion programmes. Methods: A postal questionnaire designed by the World Health Organization (WHO) was distributed worldwide to the Chief Dental Officers or country oral health focal points at ministries of health. WHO received 46 questionnaires from countries (39% response rate). In addition, systematic data were collected from the WHO Global Oral Health Data Bank and the World Health Survey in order to include oral health information on the remaining countries. In total, the data base covers 136 out 193 countries, i.e. 71% of all WHO Member States. Results: Dental caries and periodontal disease comprise a considerable public health problem in the majority of countries. Significant disparities within and between regions are observed in epidemiologic indicators of oral disease. The prevalence rates of tooth loss and experience of oral problems vary substantially by WHO Region and national income. Experience of oral problems among older people is high in low income countries; meanwhile, access to health care is poor, in particular in rural areas. Although tooth brushing is the most popular oral hygiene practice across the world, regular tooth brushing appears less common among older people than the population at large. In particular, this practice is less frequent in low income countries; in contrast, traditional oral self-care is prevalent in several countries of Africa and Asia. While fluoridated toothpaste is widely used in developed countries, it is extremely infrequent in most developing countries. Oral health services are available in developed countries; however, the use of such services is low among the older people. Lack of financial support from government and/or lack of third party payment systems render oral health services unaffordable to them. According to the country reports, health promotion programmes targeting older people are rare and this reflects the lack of oral health policies. Although some countries have introduced oral health promotion initiatives, worldwide there are few population-oriented preventive or curative activities currently implemented that focus specifically on the elderly. Barriers to the organization of such programmes relate to weak national health policy, lack of economic resources, the impact of poor oral health, and lack of tradition in oral health. Opportunities for oral health programmes for old-age people are related to updated information on the burden of oral disease and need for care, fair financing of age-friendly primary health care, integration of oral health into national health programmes, availability of oral health services, and ancillary personnel. Conclusion: It is highly recommended that countries establish oral health programmes to meet the needs of the elderly. Relevant and measurable goals must be defined to direct the selection of suitable interventions to improve their oral health. The common risk factors approach must be applied in public health interventions for disease prevention. The integration of oral health into national general health programmes may be effective to improve the oral health status and quality of life of this population group.

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  • Tooth-related risk factors for periodontal disease in community-dwelling elderly people 査読

    Toshinobu Hirotomi, Akihiro Yoshihara, Hiroshi Ogawa, Hideo Miyazaki

    JOURNAL OF CLINICAL PERIODONTOLOGY   37 ( 6 )   494 - 500   2010年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    P&gt;Objective
    While most previous epidemiological studies have focused on subject-level risk factors for periodontal destruction, tooth-related factors have not been fully explored. The purpose of this study was to evaluate both tooth-related and subject-related factors affecting periodontal disease progression using a two-level multilevel model.
    Material and Methods
    A longitudinal survey over a period of 10 years was carried out on 286 community-dwelling elderly subjects aged 70 years at baseline. Clinical attachment level (CAL) was measured at six sites per tooth on all teeth present and periodontal disease progression was defined as CAL &gt;= 3 mm.
    Results
    Periodontal disease progression was found in 79% of the subjects and most frequently in maxillary molars. Multilevel logistic regressions revealed that subjects wearing removable dentures were significantly at risk for periodontal disease progression. Abutment teeth for removable/fixed dentures were also significantly more likely to suffer periodontal breakdown. Furthermore, the following tooth-related variables were found to be possible risk factors for periodontal disease progression: maxillary and multirooted teeth.
    Conclusion
    Multirooted teeth and abutments for a fixed denture were possible risk factors for periodontal disease progression.

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  • Effect of antimicrobial periodontal treatment and maintenance on serum adiponectin in type 2 diabetes mellitus 査読

    Sayaka Matsumoto, Hiroshi Ogawa, Satoshi Soda, Satoshi Hirayama, Najith Amarasena, Yoshifusa Aizawa, Hideo Miyazaki

    JOURNAL OF CLINICAL PERIODONTOLOGY   36 ( 2 )   142 - 148   2009年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL PUBLISHING, INC  

    Matsumoto S, Ogawa H, Soda S, Hirayama S, Amarasena N, Aizawa Y, Miyazaki H. Effect of antimicrobial periodontal treatment and maintenance on serum adiponectin in Type 2 Diabetes Mellitus. J Clin Periodontol 2009; 36: -. doi: 10.1111/j.1600-051X.2008.01359.x.
    The aims of this study were to evaluate the effect of mechanical periodontal treatment with local application of minocycline (APT) on serum adiponectin as a marker of insulin resistance improvement in type 2 diabetes mellitus (T2DM) patients and to investigate if effect of APT on serum adiponectin level was sustained by periodontal maintenance (PM).
    Twenty-seven T2DM patients were randomly assigned into test or control groups. Test received scaling with ultrasonic devices at baseline and APT biweekly for 2 months while control received scaling at baseline and mechanical tooth cleaning (MPT) at the same interval. At 6 months, all patients received mechanical tooth cleaning as PM. Periodontal examination and blood measurements were performed at baseline, 4 and 9 months.
    Adiponectin concentrations in test had significantly increased by 31.4% after APT (p=0.024) and by 30.4% after PM (p=0.002) compared with baseline. The percentage of &gt;= 4 mm probing depths (PD) had shown 8.3% and 9.3% reduction after APT and PM (p=0.046, 0.02) in test while 5.0% reduction after MPT in control group (p=0.031).
    Our results suggested that APT and PM not only improve periodontal disease but also increase serum adiponectin in T2DM patients.

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  • Circulating TNF- α and oral health condition in elderly Japanese 査読

    Hideaki Hayashida, Toshiyuki Saito, Reiko Furugen, Noboru Yamaguchi, Akihiro Yoshihara, Hiroshi Ogawa, Hideo Miyazaki

    Tumor Necrosis Factor   151 - 158   2009年1月

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    © 2009 Nova Science Publishers, Inc. Objectives The oral cavity, especially area around teeth, is a hotbed for bacteria, which compose a biofilm that becomes a significant source of continuous subclinical infection. Tumor necrosis factor-α (TNF-α), which is secreted from adipose tissue and developing type 2 diabetes, is also known to be secreted in periodontal inflammation. Moreover, there is a two-way relationship between diabetes and periodontal disease. We hypothesized that the circulating level of TNF-α is associated with the oral health condition, including periodontal disease. The purpose of this study was to assess the relationship between serum levels of TNF-α and the oral health condition in elderly Japanese people. Methods Among 418 Japanese subjects, 76 years old, who attended complete oral and general health examinations held in Niigata, Japan, in 2004, the serum TNF-α levels of 198 subjects were measured by ELISA. Among them, 76 subjects with healthy gingiva (maximum probing depth ≤ 5 mm, at least 10 teeth), 85 subjects with periodontitis (maximum probing depth ≥ 6 mm, at least 10 teeth), and 37 edentulous subjects were selected. Serum levels of TNF-α were compared among the groups using the Kruskal- Wallis test. The proportions of subjects with detectable levels of TNF-α (≥ 0.5 pg/mL) were compared by chi-square test. Results The median serum TNF-α levels in subjects with healthy gingiva, those with periodontitis, and edentulous subjects were 0.64 pg/mL (range 0-16.36), 0.72 pg/mL (range 0-4.53), and 0.00 pg/mL (range 0-1.83), respectively. The frequencies of detectable TNF-α levels were 48/76 (63.2%), 53/85 (62.4%), and 6/37 (16.2%), respectively. There were no significant differences between subjects with and without periodontitis. However, TNF-α levels and the frequency of subjects with detectable levels of TNF-α were significantly lower in edentulous subjects than in other groups (P &lt; 0.001). Conclusion In this study of elderly Japanese, the circulating TNF-α levels were not affected by current periodontal status. However, they were significantly lower in edentulous subjects than in the other two dentate groups, suggesting that the oral cavity in elderly people with teeth could be a source of systemic subclinical inflammation, which may have negative effects on general health.

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  • Salivary spinability and periodontal disease progression in an elderly population 査読

    T. Hirotomi, A. Yoshihara, H. Ogawa, K. Ito, A. Igarashi, H. Miyazaki

    ARCHIVES OF ORAL BIOLOGY   53 ( 11 )   1071 - 1076   2008年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    Objective: To explore the relationship between the spinability of stimulated whole saliva and periodontal disease progression over 12 months in an elderly population.
    Methods: Three hundred and thirty-two subjects aged 76 years at baseline were studied. Attachment loss was calculated on a site-by-site basis, and periodontal disease progression was defined as an attachment loss of &gt;= 3 mm. Stimulated whole saliva was collected and salivary spinability (SS) was measured. A multiple linear regression analysis was performed to assess the relationship between periodontal disease progression and SS after controlling for other covariates. The independent variables were selected from those which had significant relationships with disease progression in the bivariate analyses.
    Results: Mean SS was 1.94 +/- 0.42 min in males and 1.88 +/- 0.32 mm in females; this difference was not significant. Simple linear regression analysis showed a significant positive relationship between periodontal disease progression and SS (P = 0.026), whereas there was no significant relationship between periodontal disease progression and salivary flow rate. Multiple regression analysis revealed a significant positive relationship between periodontal disease progression and SS (P = 0.024) after controlling for the number of remaining teeth and baseline periodontal conditions. The model explained 15.5% of the variance in the percentage of sites where the disease had progressed.
    Conclusions: These findings suggest that elderly subjects with viscous saliva are prone to periodontal disease progression. (C) 2008 Elsevier Ltd. All rights reserved.

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  • The relationship between periodontal condition and serum levels of resistin and adiponectin in elderly Japanese 査読

    R. Furugen, H. Hayashida, N. Yamaguchi, A. Yoshihara, H. Ogawa, H. Miyazaki, T. Saito

    JOURNAL OF PERIODONTAL RESEARCH   43 ( 5 )   556 - 562   2008年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WILEY-BLACKWELL  

    Background and Objective: Diabetes and periodontitis are associated with each other. Adipokines, specifically adiponectin and resistin, are secreted from adipocytes and are thought to cause insulin resistance in rodents. Additionally, adiponectin and resistin may play a role in inflammation and immune responses. The aim of this study was to clarify the relationship between serum levels of adipokines and periodontal conditions in elderly Japanese people with and without periodontitis.
    Material and Methods: A total of 158 Japanese men and women (76 years old) with or without periodontitis were selected for the study. Serum adiponectin, resistin, interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) concentrations were compared between subjects with and without periodontitis.
    Results: Serum resistin levels and total leukocyte counts in subjects with periodontitis were higher than in control subjects. No significant differences were observed in adiponectin, IL-6 and TNF-alpha levels between subjects with and without periodontitis. Logistic regression analysis showed that periodontitis with at least one tooth that displayed a probing pocket depth of &gt;= 6 mm was significantly associated with higher serum resistin levels (odds ratio, 2.0; 95% confidence interval, 1.0-4.0). When excluding periodontitis subjects with &lt;= 10% of bleeding on probing and excluding control subjects with &gt; 10% bleeding on probing, differences between groups and odds ratio increased. Serum adiponectin tended to decrease in patients with periodontitis, albeit not significantly.
    Conclusion: Increased serum resistin levels were significantly associated with periodontal condition, especially when considering bleeding on probing, in elderly Japanese people. There was also a trend, though non-significant, toward decreased levels of adiponectin in subjects with periodontitis.

    DOI: 10.1111/j.1600-0765.2008.01085.x

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  • Longitudinal study on the relationship between serum albumin and periodontal disease 査読

    Masanori Iwasaki, Akihiro Yoshihara, Toshinobu Hirotomi, Hiroshi Ogawa, Nobuhiro Hanada, Hideo Miyazaki

    JOURNAL OF CLINICAL PERIODONTOLOGY   35 ( 4 )   291 - 296   2008年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BLACKWELL PUBLISHING  

    Aim: The purpose of this study was to evaluate the relationship between periodontal disease and the general health status in community-dwelling elderly using the serum albumin concentration as a criterion index of the severity of underlying disease and nutrition.
    Material and Methods: Six hundred subjects aged 70 years underwent a baseline examination. Dental examinations were carried out at baseline and once a year for 4 years. Periodontal conditions were estimated for subjects with at least one remaining tooth. Clinical attachment levels at six sites of all teeth present were measured. A change in loss of attachment of 3 mm or greater in 1 year at each site was defined as periodontal disease progression. Data were analysed in subjects for whom data were available for 4 years.
    Results: Serum albumin concentration at baseline ranged from 3.4 to 5.0 g/dl with a mean of 4.3 +/- 0.2. When the analysis was stratified by smoking status, we found that serum albumin concentration had a significant effect on periodontal disease progression among non-smokers (standardized regression coefficient=-0.16; p=0.017), using multiple regression analysis.
    Conclusions: The findings of the present study suggest that serum albumin concentration is a significant risk predictor of periodontal disease progression among elderly non-smokers.

    DOI: 10.1111/j.1600-051X.2008.01215.x

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  • Longitudinal relationship between root caries and serum albumin 査読

    A. Yoshihara, N. Takano, T. Hirotomi, H. Ogawa, N. Hanada, H. Miyazaki

    JOURNAL OF DENTAL RESEARCH   86 ( 11 )   1115 - 1119   2007年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:INT AMER ASSOC DENTAL RESEARCHI A D R/A A D R  

    Serum albumin levels are a practical marker of general health status in the elderly and have been used to determine the severity of an underlying disease and the risk for death. This longitudinal study evaluated the relationship between serum albumin levels and root caries. A total of 266 persons with at least 1 tooth at baseline underwent a baseline examination and then annual investigations for 6 years. Multiple linear regression analysis was used to assess the relationship between changes in serum albumin levels and the number of root caries lesions over 6 years, after adjustment for confounding factors. Change in the number of root caries lesions was significantly associated with change in serum albumin concentrations. The standardized coefficient was -0.148 (p = 0.024). We can confirm that serum albumin concentration correlates with root caries events. From these data, we conclude that persons with hypoalbuminemia are at high risk for root caries.

    DOI: 10.1177/154405910708601118

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  • 高齢者集団におけるCPIとアタッチメントロス評価法(WHO)の有用性および歯周健康状態に関する5年間の縦断研究 査読

    白根和明, 小川祐司, 広冨敏伸, 高野尚子, 山賀孝之, 金子 昇, 佐久間汐子, 葭原明弘, 宮崎秀夫

    口腔衛生会誌   57 ( 1 )   28 - 35   2007年

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    記述言語:日本語   出版者・発行元:有限責任中間法人日本口腔衛生学会  

    本研究目的は,10代表歯によるWHOのCommunity Periodontal Index (CPI),アタッチメントロス(LA)評価システムが高齢者に対して有用であるかを検証し,歯周組織健康状態の経年推移を観察・検討することであった.分析対象者は,5年間すべての調査に参加した70歳313名であった.詳細な歯周健診結果をWHO口腔診査法第4版に準じCPI, LAそれぞれ0〜4のコードに変換し,口腔内を6セクスタントに分けた10代表歯と全歯を診査対象にした場合について,各個人最高コードとコード別セクスタントの割合を算出した.分析の結果,治療勧告となるCPI-1以上のコードをもつ者が10代表歯診査で93.7%,全歯診査で97.4%認められた.LA-1以上ではそれぞれ66.9, 78.8%となった.全歯診査による結果をゴールドスタンダードとした場合の10代表歯診査の敏感度は,CPI-3以上で76.1%, LA-1以上で84.9%を示した.また,歯周ポケット6mm以上を示すCPI-4を個人最高コードにもつ者は5年間で51,7%,アタッチメントロス9mm以上であるLA-3以上を個人最高コードにもつ者は43.2%増加した.本研究結果から,高齢者では重度の歯周疾患有病部位が増加していることが明らかとなり.10代表歯を用いたCPI, LA評価による重度歯周疾患有病部位のモニタリングが口腔健康を保つうえで有用かつ必要であることが示唆された.

    DOI: 10.5834/jdh.57.1_28

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  • A preliminary study on the relationship between stimulated saliva and periodontal conditions in community-dwelling elderly people 査読

    T. Hirotomi, A. Yoshihara, H. Ogawa, K. Ito, A. Igarashi, H. Miyazaki

    JOURNAL OF DENTISTRY   34 ( 9 )   692 - 698   2006年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCI LTD  

    objectives: The purpose of this study was to explore the relationship between flow rate and spirmbarkeit of stimulated whole saliva and periodontal conditions in healthy elderly people.
    Methods: Three hundred and fifty-five dentate subjects aged 76 years were included. The pocket probing depth (PD), attachment level (AL), and bleeding on probing (BOP) were measured. Stimulated whole saliva was collected and the salivary flow rate (SFR) was calculated. Then, salivary spirmbarkeit (SS) was immediately measured.
    Results: The mean SFR and SS were 1.44 ml/min and 1.91 mm, respectively. SFR was not significantly related to each periodontal parameter. On the other hand, subjects with SS &lt;= 2.00 mm had a significantly lower mean AL (p &lt; 0.05). When subjects were divided into four groups according to a combination of SFR and SS, subjects with SFR &lt; 0.7 ml/min and SS &gt; 2.00 mm exhibited a significantly higher mean PD (p &lt; 0.05), % of sites with PD &gt;= 4 mm (p &lt; 0.05), mean AL (p &lt; 0.01), % of site with AL &gt;= 4 mm (p &lt; 0.05) and % of sites with AL &gt;= 6 mm (p &lt; 0.01) than subjects in the other three groups (one-way ANOVA). In the logistic regression analysis, the factors significantly associated with the highest quintile of PD &gt;= 4 mm were: the low salivary flow and the high salivary spirmbarkeit (OR 3.84), current smokers (OR 5.08), cleaning interdental spaces rarely/never (OR 2.12), and frequent BOP (OR 5.20).
    Conclusion: These findings suggest that high salivary spirmbarkeit in addition to a low salivary flow rate might be a high risk for periodontal disease in elderly people. (C) 2006 Elsevier Ltd. All rights reserved.

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  • Association between serum albumin and periodontal disease in community-dwelling elderly 査読

    H Ogawa, A Yoshihara, N Amarasena, T Hirotomi, H Miyazaki

    JOURNAL OF CLINICAL PERIODONTOLOGY   33 ( 5 )   312 - 316   2006年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BLACKWELL PUBLISHING  

    Aim: The purpose of this study was to evaluate the relationship between periodontal disease and general health status in community-dwelling elderly using serum albumin concentration as a criterion index of the severity of an underlying disease and nutrition status.
    Methods: Serum albumin level was detected by the bromcresol green albumin (BCG) method and the data for serum albumin were available in 368 subjects aged 75 years. Pressure-sensitive probes were used to measure loss of attachment (LA) on six sites of all teeth present. Information relevant to gender and smoking habit was obtained by means of a personal interview, while body mass index (BMI) and biochemical serum markers were investigated.
    Results: Serum albumin concentration ranged from 3.2 to 4.8 g/dl with a mean of 4.1 +/- 0.2. More than 70% of subjects had at least one site with LA 6+ mm, while 91 exhibited 10% or more sites with LA 6+ mm. Using a multiple regression analysis, we found that sites of LA 6+ mm had a significant effect on serum albumin level (correlation coefficient=-0.14; p &lt; 0.05), which was independent of the other covariates.
    Conclusions: The findings of the present study indicated that there might be an inverse relationship between periodontal disease and serum albumin concentration in these elderly subjects.

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  • Strengthening the prevention of periodontal disease – the approach of WHO 査読

    P E Petersen, H Ogawa

    J Periodontol   76 ( 12 )   2187 - 2193   2005年12月

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  • Relationship between bleeding on probing and periodontal disease progression in community-dwelling older adults 査読

    A Rahardjo, A Yoshihara, N Amarasena, H Ogawa, K Nakashima, H Miyazaki

    JOURNAL OF CLINICAL PERIODONTOLOGY   32 ( 11 )   1129 - 1133   2005年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BLACKWELL PUBLISHING  

    Objective: The main objective of this study was to determine the relationship between bleeding on probing (BOP) and periodontal disease progression in community-dwelling older adults.
    Methods: A 3-year longitudinal study was carried out in 229 non-smoking healthy older adults aged 70 years. Using pressure-controlled periodontal probes, BOP, pocket depth and attachment level at 13,289 sites were measured annually. Periodontal disease progression was defined as an increase in attachment loss of &gt;= 3mm from the baseline to the final examination. The backward stepwise logistic regression analysis was performed to assess the relationship between the total number of sites with BOP in the four examinations and periodontal progression.
    Results: Logistic regression analysis showed that the odds ratios of BOP frequency for periodontal disease progression ranged from 1.4 to 6.2 after controlling for pocket depth &gt;= 4mm at baseline, number of missing teeth, jaw type and tooth site.
    Conclusion: Increasing frequencies of bleeding might increase the probability of periodontal disease progression in community-dwelling older adults.

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  • Oral health information systems — towards measuring progress in oral health promotion and disease prevention 査読

    P E Petersen, D Bourgeois, D Bratthall, H Ogawa

    Bulletin of the World Health Organization   83 ( 9 )   686 - 693   2005年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • The global burden of oral diseases and risks to oral health 査読

    PE Petersen, D Bourgeois, H Ogawa, S Estupinan-Day, C Ndiaye

    BULLETIN OF THE WORLD HEALTH ORGANIZATION   83 ( 9 )   661 - 669   2005年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:WORLD HEALTH ORGANIZATION  

    This paper outlines the burden of oral diseases worldwide and describes the influence of major sociobehavioural risk factors in oral health. Despite great improvements in the oral health of populations in several countries, global problems still persist. The burden of oral disease is particularly high for the disadvantaged and poor population groups in both developing and developed countries. Oral diseases such as dental caries, periodontal disease, tooth loss, oral mucosal lesions and oropharyngeal cancers, human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS)-related oral disease and orodental trauma are major public health problems worldwide and poor oral health has a profound effect on general health and quality of life. The diversity in oral disease patterns and development trends across countries and regions reflects distinct risk profiles and the establishment of preventive oral health care programmes. The important role of sociobehavioural and environmental factors in oral health and disease has been shown in a large number of socioepidemiological surveys.-In addition to poor living conditions, the major risk factors relate to unhealthy lifestyles (i.e. poor diet, nutrition and oral hygiene and use of tobacco and alcohol), and limited availability and accessibility of oral health services. Several oral diseases are linked to noncommunicable chronic diseases primarily because of common risk factors. Moreover, general diseases often have oral manifestations (e.g. diabetes or HIV/AIDS). Worldwide strengthening of public health programmes through the implementation of effective measures for the prevention of oral disease and promotion of oral health is urgently needed. The challenges of improving oral health are particularly great in developing countries.

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  • FcγRIIIb genotypes and smoking in periodontal disease progression among community-dwelling older adults in Japanese 査読

    A Yoshihara, N Sugita, K Yamamoto, T Kobayashi, T Hirotomi, H Ogawa, H Miyazaki, H Yoshie

    J. Periodontol   76 ( 2 )   250 - 255   2005年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1902/jop.2005.76.2.250

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  • Serum vitamin C-periodontal relationship in community-dwelling elderly Japanese 査読

    N Amarasena, H Ogawa, A Yoshihara, N Hanada, H Miyazaki

    JOURNAL OF CLINICAL PERIODONTOLOGY   32 ( 1 )   93 - 97   2005年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BLACKWELL MUNKSGAARD  

    Objective: To determine the relationship between serum vitamin C and periodontitis as estimated by clinical attachment loss (CAL) in community-dwelling elderly Japanese.
    Material and Methods: This analysis was confined to 413 Niigata citizens aged 70 years in whom the data for serum vitamin C and CAL were available. High-pressure liquid chromatography method was used to ascertain the serum vitamin C levels while CAL was assessed on six sites of all teeth present including third molars by means of pressure-sensitive probes. Other variables included gender, smoking, toothbrushing frequency, number of teeth present and random blood sugar levels.
    Results: Serum vitamin C concentration was inversely related to CAL (r=-0.23, p&lt;0.00005) at bivariate level. Multiple linear regression analysis showed that CAL was 4% greater in subjects with lower serum vitamin C levels than in subjects with higher serum vitamin C levels notwithstanding smoking, diabetes, oral hygiene, gender or number of teeth present.
    Conclusion: The findings suggested that serum vitamin C might have relatively weak but a statistically significant relationship with periodontitis in this elderly population.

    DOI: 10.1111/j.1600-051X.2004.00643.x

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  • 高齢者の根面う蝕の有病状況と歯冠う蝕との関連

    高野 尚子, 葭原 明弘, 安藤 雄一, 小川 祐司, 廣富 敏伸, 山賀 孝之, 花田 信弘, 宮崎 秀夫

    口腔衛生学会雑誌   53 ( 5 )   592 - 599   2003年10月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

    有歯顎者554名(男281名,女273名,70歳).一人平均現在歯数は18.8で,性差はなかった.根面の未処置・処置齲蝕(根面DF)は男の56.9%,女の53.5%が所有し,未処置齲蝕(根面D)は各々21.7%,19.8%が所有していた.一人平均根面DF数は男1.8,女1.4で,根面D数は各々0.46,0.32であった.根面齲蝕が露出歯根面に占める割合は,上顎では犬歯,切歯,小臼歯,大臼歯の順に高く,下顎は小臼歯,犬歯,切歯,大臼歯の順であった.未処置齲蝕は下顎の切歯が最も低かった.歯面別にみると,根面DFの割合は頬側,遠心,近心,舌側の順に高く,根面Dは遠心,近心,頬側,舌側の順であった.歯冠部の未処置・処置齲蝕(歯冠DF)は男の95.0%,女の99.6%が所有し,歯冠Dは各々18.1%,15.4%,一人平均歯冠DF数は9.5,11.7であった.歯冠DFが多い者は根面DFの所有者率が高く,歯冠DFが14歯以上の者は根面DF所有者率61.9%であった

    DOI: 10.5834/jdh.53.5_592

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  • A pilot study of dental caries status in relation to knowledge, attitudes and practices in oral health in Myanmar 査読

    H. Ogawa, P. Soe, B. Myint, K. Sein, M. M. Kyaing, K. K. Maw, H. M. Oo, M. Murai, H. Miyazaki

    Asia-Pacific Journal of Public Health   15 ( 2 )   111 - 117   2003年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Asia-Pacific Academic Consortium for Public Health  

    This study was to determine the dental caries prevalence among the Myanmar population, and to investigate the correlations between oral clinical indices and knowledge, attitudes and practices (KAP) on oral health. Subjects were randomly selected from 140,000 people residing in the Kyauktan township in a cross-sectional community-based study. The present analysis was confined to 739 subjects (353 males and 386 females) aged 12, 35-44 and 65-74 years, who were divided into two specified groups based on urban or rural location. KAP on oral health data and social demographc information were collected, while dental caries status was assessed by DMFT. The mean number of decayed teeth (DT) in rural areas was higher than that in urban areas, while the mean number of filled teeth (FT) in rural areas was lower than that in urban areas. Mean knowledge and attitude scores for correct answers were also significantly higher for the urban than the rural subjects. There were statistically significant correlations between the correct/incorrect responses to knowledge and attitude questionnaires on oral health and the mean number of DMFT. KAP pertaining to oral health of Myanmar population, especially those of rural subjects, might not be satisfactory and related to threaten their dental caries status.

    DOI: 10.1177/101053950301500207

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  • Risk factors for periodontal disease progression among elderly people 査読

    H Ogawa, A Yoshihara, T Hirotomi, Y Ando, H Miyazaki

    JOURNAL OF CLINICAL PERIODONTOLOGY   29 ( 7 )   592 - 597   2002年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BLACKWELL MUNKSGAARD  

    The aim of this study was to identify the risk factors for periodontal disease progression by individual characteristics at baseline among elderly people over a 2-year period. Subjects were selected from 4542 people aged 70 years residing in Niigata who were in good general health and who did not require special care for their daily activities. Gender, smoking and alcohol drinking habits were obtained using a questionnaire, while serum levels of disease markers were investigated and attachment levels were clinically recorded. For the assessment of periodontal disease progression, additional attachment loss was used if one or more sites had a 3-mm or more increase in probing attachment level over a 2-year period. In all, 394 subjects (208 males and 186 females) were surveyed. Approximately 75% of subjects exhibited additional attachment loss over a 2-year period. Significant associations were found between additional attachment loss and smoking, and attachment level of 6 mm or more at baseline, with odds ratios of 3.75 and 2.29, respectively. Smoking habit and baseline attachment level of 6 mm or more may be considered risk factors for further attachment loss among healthy elderly people.

    DOI: 10.1034/j.1600-051X.2002.290702.x

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  • Knowledge practice on fluoride utilization and tea drinking habits of three 査読

    IL Parajas, H Miyazaki, H Ogawa

    Journal of Philippine Dental Association   52 ( 3 )   3 - 14   2001年

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  • Natural fluoride content of drinking waters and dental status of selected communities in the Philippies 査読

    IL Parajas, H Miyazaki, H Ogawa

    Journal of Philippies Dental Association   52 ( 2 )   4 - 14   2000年

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書籍等出版物

  • 口腔保健と栄養を結ぶ

    小川 祐司( 担当: 分担執筆 ,  範囲: 第1章グローバルな動向, 第3章砂糖摂取・肥満と口腔保健)

    医歯薬出版  2019年8月 

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  • 臨床歯科栄養学

    小川 祐司( 担当: 分担執筆 ,  範囲: WHOが提唱する砂糖コントロール)

    口腔保健協会  2018年10月 

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  • 高齢者歯周治療と口腔管理

    小川 祐司( 担当: 分担執筆 ,  範囲: WHOが提唱するNCDsと歯周病の関連性から考える)

    インターアクション  2018年3月 

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  • デンタルスタッフの口腔衛生学

    小川 祐司( 担当: 分担執筆 ,  範囲: 口腔保健と公衆衛生)

    医歯薬出版  2018年2月 

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  • WHO technical information note -Sugar and dental caries

    小川 祐司( 担当: 共編者(共編著者))

    世界保健機関  2017年8月 

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    WHO出版物は国際機関の慣習上,編纂・執筆者の名前記載が禁止されている

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  • WHO monograph on tobacco cessation and oral health integration

    小川 祐司( 担当: 共編者(共編著者))

    世界保健機関  2017年6月 

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    WHO出版物は国際機関の慣習上,編纂・執筆者の名前記載が禁止されている

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  • A guide for oral disease patients to quit tobacco use

    小川 祐司( 担当: 共編者(共編著者))

    世界保健機関  2017年6月 

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    WHO出版物は国際機関の慣習上,編纂・執筆者の名前記載が禁止されている

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  • WHO expert consultation on public health intervention against early childhood caries

    小川 祐司( 担当: 編集)

    世界保健機関  2017年3月 

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    WHO出版物は国際機関の慣習上,編纂・執筆者の名前記載が禁止されている

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  • 口腔保健・予防歯科学

    小川 祐司( 担当: 分担執筆 ,  範囲: 国際口腔保健)

    医歯薬出版  2017年2月 

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  • 口腔診査法 WHOによるグローバルスタンダード

    眞木 吉信, 宮崎 秀夫, 山本 龍生, 小川 祐司( 担当: 共訳)

    口腔保健協会  2016年  ( ISBN:9784896053166

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    記述言語:日本語

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MISC

  • 健康寿命延伸のための歯科口腔保健 -グローバルな視点で考える- 招待 査読

    小川 祐司

    Aging Science   12   41 - 45   2019年11月

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    記述言語:日本語   掲載種別:記事・総説・解説・論説等(学術雑誌)  

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  • 歯科医院における禁煙指導の意義とポイント WHOの簡易タバコ介入プログラムを用いて

    小川 祐司, 埴岡 隆, 小島 美樹, 南崎 信樹, 上領 梨華

    日本歯科評論   78 ( 3 )   133 - 143   2018年3月

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    記述言語:日本語   出版者・発行元:(株)ヒョーロン・パブリッシャーズ  

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  • 高齢者における口腔と栄養

    岩崎 正則, 小川 祐司, 木村 友美, 葭原 明弘, 宮崎 秀夫

    ヘルスサイエンス・ヘルスケア   17 ( 2 )   46 - 52   2017年12月

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    記述言語:日本語   出版者・発行元:深井保健科学研究所  

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  • 委員会報告 「口腔保健の新定義」に関する動向

    深井 穫博, 佐々木 健, 野村 圭介, 大内 章嗣, 安藤 雄一, 小川 祐司, 岡田 寿郎, 嶋﨑 義浩, 宮﨑 秀夫, 竹内 研時, 花田 信弘, 神原 正樹

    口腔衛生学会雑誌 = Journal of dental health : official publication of Japanese Society for Oral Health   67 ( 4 )   306 - 310   2017年10月

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    記述言語:日本語   出版者・発行元:日本口腔衛生学会  

    CiNii Article

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  • 歯科医師・歯科衛生士養成機関における禁煙介入教育の課題と展望

    埴岡 隆, 青山 旬, 川口 陽子, 小島 美樹, 日野出 大輔, 尾崎 哲則, 山中 玲子, 瀬川 洋, 細見 環, 田野 ルミ, 千葉 逸朗, 小川 祐司, 平田 幸夫, 三宅 達郎, 谷口 奈央, 井下 英二, 花田 信弘, 眞木 吉信, 於保 孝彦, 日本口腔衛生学会禁煙推進委員会

    口腔衛生学会雑誌   67 ( 4 )   298 - 305   2017年10月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • タバコ使用歯科介入の卒前教育への提言 世界の文献レビューと最新の背景から

    埴岡 隆, 青山 旬, 川口 陽子, 小島 美樹, 日野出 大輔, 尾崎 哲則, 山中 玲子, 瀬川 洋, 細見 環, 田野 ルミ, 小川 祐司, 平田 幸夫, 花田 信弘, 井下 英二, 谷口 奈央, 眞木 吉信, 於保 孝彦, 日本口腔衛生学会禁煙推進委員会

    口腔衛生学会雑誌   67 ( 1 )   35 - 39   2017年1月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

    わが国の歯科医師・歯科衛生士の国家試験出題基準および教育モデルには、タバコ使用に関する医療面接および使用介入の内容が掲載されている。喫煙率の低下目標の達成に資するために、世界のタバコ使用介入の歯科教育の文献レビューを行った。また、タバコ使用介入の歯科卒前教育への提言を行った。日本のタバコ使用中止介入の教育実態および教育者の意識の把握により、行動目標の基盤となる介入レベルの判断や教育モデルの策定が行われる必要があると思われた。

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  • 健康寿命延伸のため歯科口腔保健 WHOの戦略 査読

    小川祐司

    公衆衛生   81 ( 1 )   15 - 20   2017年1月

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  • グローバルヘルスの観点からみた歯科医療・口腔保健 口腔保健の指針作成に対するWHOの取り組み 招待

    小川 祐司

    歯界展望   130 ( 1 )   188 - 189   2017年1月

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    記述言語:日本語   掲載種別:記事・総説・解説・論説等(商業誌、新聞、ウェブメディア)  

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  • WHOの簡易禁煙介入プログラムと日本の歯科禁煙教育モデルの比較

    尾崎和歌子, 蓮田賀子, 埴岡隆, 原田有理子, 竹内研時, 小川祐司

    口腔衛生学会雑誌   66 ( 2 )   293   2016年4月

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    記述言語:日本語  

    J-GLOBAL

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  • 【歯科が発信するコモンリスクファクター対策】 コモンリスクファクターアプローチ WHO口腔保健の取り組み

    小川 祐司

    The Quintessence   35 ( 1 )   109 - 109   2016年1月

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    記述言語:日本語   掲載種別:記事・総説・解説・論説等(商業誌、新聞、ウェブメディア)   出版者・発行元:クインテッセンス出版(株)  

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  • 高齢者の口腔保健 世界事情とWHOの取り組み

    小川 祐司

    8020: はち・まる・にい・まる   ( 15 )   20 - 23   2016年1月

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    記述言語:日本語   出版者・発行元:(公財)8020推進財団  

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  • 世界会議2015の成果とその後。日本が世界に発信すべきは?

    小川 祐司, 山科 透, 深井 穫博

    8020: はち・まる・にい・まる   ( 15 )   8 - 19   2016年1月

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    記述言語:日本語   出版者・発行元:(公財)8020推進財団  

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  • 口腔保健推進とWHOによる砂糖摂取量ガイドライン

    角田 衣理加, 小川 祐司

    歯界展望   126 ( 3 )   421 - 424   2015年9月

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    記述言語:日本語   出版者・発行元:医歯薬出版(株)  

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  • 健康寿命延伸に向けて WHOと日本歯科医師会の取り組み

    Bettcher Douglas W, 大久保 満男, 小川 祐司, 佐原 康之, 中島 信也

    日本歯科医師会雑誌   68 ( 3 )   194 - 200   2015年6月

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    記述言語:日本語   出版者・発行元:(公社)日本歯科医師会  

    CiNii Article

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    その他リンク: http://search.jamas.or.jp/link/ui/2015274933

  • 世界の中の日本 世界会議2015へ向けて

    小川 祐司, 大久保 満男, 深井 穫博

    8020: はち・まる・にい・まる   ( 14 )   8 - 17   2015年1月

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    記述言語:日本語   出版者・発行元:(公財)8020推進財団  

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  • 口腔で使用される無煙タバコの健康被害とタバコ対策への影響

    埴岡 隆, 青山 旬, 稲葉 大輔, 小川 祐司, 小島 美樹, 川口 陽子, 小林 清吾, 千葉 逸朗, 平田 幸夫, 岡崎 好秀, 日野出 大輔, 三宅 達郎, 花田 信弘, 尾崎 哲則, 日本口腔衛生学会禁煙推進委員会

    口腔衛生学会雑誌   64 ( 5 )   420 - 424   2014年10月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 歯科医師・歯科衛生士の卒前臨床教育における禁煙指導・支援の実態および意識に関する教育機関全国調査

    埴岡 隆, 花田 信弘, 稲葉 大輔, 小川 祐司, 小島 美樹, 川口 陽子, 平田 幸夫, 日野出 大輔, 青山 旬, 尾崎 哲則, 日本口腔衛生学会禁煙推進委員会

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   33回   77 - 77   2014年7月

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    記述言語:日本語   出版者・発行元:(一社)日本歯科医学教育学会  

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  • 日本で発売された口腔内使用無煙タバコ(スヌース)に関連する資料

    埴岡 隆, 青山 旬, 稲葉 大輔, 小川 祐司, 尾崎 哲則, 小島 美樹, 川口 陽子, 小林 清吾, 千葉 逸朗, 平田 幸夫, 岡崎 好秀, 日野出 大輔, 三宅 達郎, 花田 信弘, 日本口腔衛生学会禁煙推進委員会

    口腔衛生学会雑誌   64 ( 1 )   34 - 37   2014年1月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 歯科口腔保健領域におけるたばこ対策の更なる推進のために 歯科医師および歯科衛生士による禁煙指導・禁煙支援の文献レビューによる今後の禁煙推進活動への提言

    埴岡 隆, 青山 旬, 稲葉 大輔, 小川 祐司, 尾崎 哲則, 小島 美樹, 川口 陽子, 小林 清吾, 千葉 逸朗, 平田 幸夫, 岡崎 好秀, 日野出 大輔, 三宅 達郎, 花田 信弘, 日本口腔衛生学会禁煙推進委員会

    口腔衛生学会雑誌   63 ( 5 )   453 - 457   2013年10月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 禁煙指導・禁煙支援のための歯学/歯科衛生学臨床教育カリキュラムの提案

    埴岡 隆, 花田 信弘, 稲葉 大輔, 小川 祐司, 尾崎 哲則, 小島 美樹, 川口 陽子, 平田 幸夫, 青山 旬, 千葉 逸朗, 一般社団法人日本口腔衛生学会禁煙推進委員会

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   32回   147 - 147   2013年7月

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    記述言語:日本語   出版者・発行元:(一社)日本歯科医学教育学会  

    J-GLOBAL

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  • P-60 2型糖尿病患者のアディポネクチン遺伝子多型と歯周病との関連性について(ポスター)

    堀 沙耶香, 小川 祐司, 皆川 久美子, 佐藤 美寿々, 宮崎 秀夫

    口腔衛生学会雑誌   63 ( 2 )   2013年4月

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    記述言語:日本語   出版者・発行元:有限責任中間法人日本口腔衛生学会  

    CiNii Article

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  • 健康政策の観点からの「禁煙指導・禁煙支援」の歯学教育・歯科衛生学教育

    埴岡 隆, 花田 信弘, 青山 旬, 稲葉 大輔, 小川 祐司, 尾崎 哲則, 小島 美樹, 川口 陽子, 平田 幸夫

    口腔衛生学会雑誌   63 ( 2 )   145 - 145   2013年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

    CiNii Article

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  • 歯科における禁煙診療の標準化と教育・研修モデル

    埴岡 隆, 花田 信弘, 青山 旬, 稲葉 大輔, 小川 祐司, 尾崎 哲則, 小島 美樹, 川口 陽子, 小林 清吾, 千葉 逸朗, 平田 幸夫, 柴原 孝彦, 森田 学, 伊東 隆利, 望月 友美子, 一般社団法人日本口腔衛生学会禁煙推進委員会

    日本歯科医師会雑誌   65 ( 5 )   652 - 652   2012年8月

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    記述言語:日本語   出版者・発行元:(公社)日本歯科医師会  

    J-GLOBAL

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  • 歯科医学教育における禁煙指導・禁煙支援 系統的文献レビューとカリキュラム開発

    埴岡 隆, 花田 信弘, 稲葉 大輔, 小川 祐司, 尾崎 哲則, 小島 美樹, 川口 陽子, 平田 幸夫, 柴原 孝彦, 森田 学, 伊東 隆利, 一般社団法人日本口腔衛生学会禁煙推進委員会

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   31回   137 - 137   2012年7月

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    記述言語:日本語   出版者・発行元:(一社)日本歯科医学教育学会  

    J-GLOBAL

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  • 「公衆衛生」、「地域保健」、「口腔保健」の定義 デルファイ法を用いた合意形成過程とその収束結果

    深井 穫博, 相田 潤, 安細 敏弘, 伊藤 博夫, 小川 祐司, 小関 健由, 佐々木 健, 白石 雅照, 千葉 逸朗, 鶴本 明久, 八重垣 健, 日本口腔衛生学会地域口腔保健委員会

    口腔衛生学会雑誌   62 ( 2 )   206 - 206   2012年4月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

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  • 血清アルブミンと歯周病の関係についての経年的評価

    岩崎 正則, 葭原 明弘, 廣冨 敏伸, 小川 祐司, 花田 信弘, 宮崎 秀夫

    新潟歯学会雑誌   38 ( 1 )   46 - 46   2008年6月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

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  • 高齢者集団におけるCPIとLA評価法(WHO)の有用性および歯周健康状態に関する5年間の縦断研究

    小川 祐司, 広冨 敏伸, 山賀 孝之, 高野 尚子, 白根 和明, 宮崎 秀夫

    口腔衛生学会雑誌 = JOURNAL OF DENTAL HEALTH   56 ( 4 )   2006年8月

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    記述言語:日本語  

    CiNii Article

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  • 高齢者の咀嚼能力と日常生活動作遂行能力との関連性

    清田 義和, 葭原 明弘, 小川 祐司, 廣冨 敏伸, 山賀 孝之, 高野 尚子, 片岡 照二郎, 濃野 要, 宮崎 秀夫

    口腔衛生学会雑誌 = JOURNAL OF DENTAL HEALTH   54 ( 4 )   2004年8月

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    記述言語:日本語  

    CiNii Article

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  • 診査部位数減少による歯周病進行率の過小評価に関する研究

    廣冨 敏伸, 葭原 明弘, 小川 祐司, 山賀 孝之, 高野 尚子, 清田 義和, 宮崎 秀夫

    口腔衛生学会雑誌   53 ( 4 )   2003年8月

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    記述言語:日本語  

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  • 高齢者の口腔内揮発性硫化物と歯周疾患の関係

    山賀 孝之, ANTON Rahardjo, 小川 祐司, 高野 尚子, 廣富 敏伸, 金子 昇, 宮崎 秀夫

    口腔衛生学会雑誌   53 ( 4 )   2003年8月

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    記述言語:日本語  

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  • 高齢者歯科学への学際的アプローチ

    葭原 明弘, 清田 義和, 小川 祐司, 高野 尚子, 廣富 敏伸, 山賀 孝之, 金子 昇, 佐久間 汐子, 八木 稔, 宮崎 秀夫

    新潟歯学会雑誌   33 ( 1 )   1 - 9   2003年7月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

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  • Influence of tobacco smoking and the serum level of vitamin C on periodontal disease in elderly patients.

    H. Ogawa, A. Yoshihara, N. Amarasena, H. Miyazaki

    JOURNAL OF DENTAL RESEARCH   82   B362 - B362   2003年6月

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    記述言語:英語   掲載種別:研究発表ペーパー・要旨(国際会議)   出版者・発行元:INT AMER ASSOC DENTAL RESEARCHI A D R/A A D R  

    Web of Science

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  • 高齢者における歯周疾患進行のリスクファクターの研究

    小川 祐司, 宮崎 秀夫, Ogawa Hiroshi, Miyazaki Hideo

    新潟歯学会雑誌   31 ( 2 )   79 - 81   2001年12月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

    CiNii Article

    CiNii Books

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  • 高齢者を対象とした歯科疫学調査におけるサンプルの偏りに関する研究 質問紙の回答状況および健診受診の有無別にみた口腔および全身健康状態の比較

    安藤 雄一, 葭原 明弘, 清田 義和, 廣富 敏伸, 小川 祐司, 金子 昇, 高野 尚子, 山賀 孝之, 王 晶, 神森 秀樹, 岸 洋志, 花田 信弘, 宮崎 秀夫

    口腔衛生学会雑誌   50 ( 3 )   322 - 333   2000年7月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

    口腔診査結果から算出された健診受診者の現在歯数の平均値は,母集団の推定値に比べ,70歳では2.6〜3.9本,80歳では0.8〜1.8本多いことが確認された.健康度については,質問紙の回収時期による差が認められたが,全般的に現在歯数の差の程度と比べると小さかった.以上より,高齢者を対象とした歯科健診を希望制により実施する場合には,全身的な健康状態よりも現在歯数によるバイアスが生じる可能性が大きいことが示された

    DOI: 10.5834/jdh.50.3_322

    CiNii Article

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  • 新潟大学歯学部附属病院外来患者の受療行動と満足度に関する調査

    濃野 要, 小川 祐司, 平川 敬, 宮崎 秀夫

    新潟歯学会雑誌   29 ( 2 )   169 - 173   1999年12月

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    記述言語:日本語   出版者・発行元:新潟歯学会  

    本学歯学部附属病院の通院・受診しやすい環境づくりを考える上で疾病治療ならびに健康状態の主観的改善,そして医師の技能や説明には高い信頼と評価が得られたものの,事務部門の対人関係を含めた病院を取り巻く諸設備には患者サービスの視点から改善すべき点がある

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  • <その他>新潟大学歯学部附属病院外来患者の受療行動と満足度に関する調査

    小川 祐司, 平川 敬, 宮崎 秀夫[他]

    新潟歯学会雑誌   29 ( 2 )   45 - 49   1999年12月

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    記述言語:日本語   出版者・発行元:新潟大学  

    CiNii Article

    CiNii Books

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  • 高齢者の根面う蝕と歯冠う蝕の有病状況

    高野 尚子, 安藤 雄一, 小川 祐司, 廣富 敏伸, 山賀 孝之, 葭原 明弘, 宮崎 秀夫, 花田 信弘

    口腔衛生学会雑誌   49 ( 4 )   612 - 613   1999年9月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

    CiNii Article

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  • 高齢者の現在歯数が栄養摂取に及ぼす影響

    神森 秀樹, 葭原 明弘, 安藤 雄一, 小川 祐司, 高野 尚子, 廣富 敏伸, 山賀 孝之, 宮崎 秀夫, 花田 信弘

    口腔衛生学会雑誌   49 ( 4 )   728 - 729   1999年9月

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    記述言語:日本語   出版者・発行元:(一社)日本口腔衛生学会  

    CiNii Article

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▶ 全件表示

講演・口頭発表等

  • 2030年に向けての口腔保健(オーラルヘルスプロモーション)戦略 招待

    小川 祐司

    第72回東北地区歯科医学会  2019年11月 

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    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(指名)  

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  • 世界(WHO)と日本の むし歯制御戦略 招待

    小川 祐司

    日本歯科保存学会市民フォーラム  2019年9月 

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    記述言語:日本語   会議種別:公開講演,セミナー,チュートリアル,講習,講義等  

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  • 学童期における唾液中乳酸脱水素酵素とストレスの関係

    田村浩平, 葭原明弘, 諏訪間加奈, 角田聡子, 岩崎正則, 安細敏弘, 小川祐司

    第30回甲信越北陸保健研究会  2019年7月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 歯肉自己観察の歯周病スクリーニングにおける有用性

    市川優, 葭原明弘, 山田智子, 杉本智子, 林悠子, 皆川久美子, 小川祐司

    第30回甲信越北陸保健研究会  2019年7月 

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    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Impact of WHO brief-tobacco intervention training on oral-health professionals in Japan 国際会議

    T Hanioka, N Suzuki, M Naito, Y Takaesu, M Ojima, H Ogawa, R Tano

    97th IADR  2019年6月 

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    記述言語:英語   会議種別:ポスター発表  

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  • アジア高齢者口腔保健研究コンソーシアムについて

    小川 祐司

    第68回日本口腔衛生学会・総会  2019年5月 

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    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(指名)  

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  • 地域在宅超高齢者の食事パターンと栄養状態 栄養素摂取量および嚥下との関連

    濱嵜朋子, 岩崎正則, 角田聡子, 片岡正太, 濃野 要, 葭原明弘, 小川祐司, 安細敏弘, 宮﨑秀夫

    第68回日本口腔衛生学会・総会  2019年5月 

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    記述言語:日本語   会議種別:ポスター発表  

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  • 動脈硬化と歯周病との関連:地域在住高齢者を対象とした横断研究

    佐藤美寿々, 岩崎正則, 皆川久美子, 山賀孝之, 小川祐司

    第68回日本口腔衛生学会・総会  2019年5月 

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    記述言語:日本語   会議種別:ポスター発表  

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  • WHO推奨歯科簡易タバコ介入の日本版e-learningの開発

    埴岡 隆, 谷口奈央, 渡辺 猛, 島津 篤, 内藤麻利江, 高江洲 雄, 廣藤卓雄, 小島美樹, 小川祐司

    第40回九州口腔衛生学会総会  2018年10月 

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    記述言語:日本語   会議種別:ポスター発表  

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  • Implication of WHO Guideline on Sugars for oral health professionals 国際会議

    小川 祐司

    第8回 日本国際歯科大会  2018年10月 

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    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(指名)  

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  • Integrating Tobacco Interventions in Oral Health Program for Healthier Ecosystem 国際会議

    T Hanioka, M Morita, T Takeshita, N Hanada, H Shigeishi, M Sugiyama, M Ojima, H Ogawa, T Nagao

    96th IADR  2018年7月 

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    記述言語:英語   会議種別:ポスター発表  

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  • WHO提唱のタバコ禁煙と口腔保健 国際会議

    小川 祐司

    WHOが推奨する簡易歯科禁煙支援研修会  2018年6月 

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    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(指名)  

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  • 可撤性部分床義歯を装着した自立高齢者の口腔衛生管理に関する予備調査

    多田紗弥夏, 藤原茂弘, 小川祐司, 倉嶋敏明, 小野高裕

    日本補綴歯科学会第127回学術大会  2018年6月 

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    記述言語:日本語   会議種別:ポスター発表  

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  • 日本の歯科医療へのWHO簡易タバコ介入法の統合導入研修プログラム開発

    埴岡 隆, 廣藤卓雄, 谷口奈央, 小島美樹, 小川祐司

    第67回日本口腔衛生学会・総会  2018年5月 

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    記述言語:日本語   会議種別:ポスター発表  

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  • Prevention and control of oral disease; Integration NCD and oral health - WHO perspectives 招待

    小川 祐司

    Continuing Medical Education for Oral Health, Ministry of Health in Palau, Korol (Palau)  2018年3月 

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  • Integrating brief tobacco interventions into oral health programme in primary care in Japan and Thailand

    小川 祐司

    17th World Conference on Tobacco or Health  2018年3月 

     詳細を見る

  • Oral health for healthy ageing 招待

    小川 祐司

    International Conference on Oral Health for Healthy Ageing  2017年11月 

     詳細を見る

  • Phasing-down use of dental amalgam 招待

    小川 祐司

    WHO SOUTH EAST ASIA REGIONAL WORKSHOP OF HEALTH SECTOR INVOLVEMENT IN THE IMPLEMENTATION OF THE MINAMATA CONVENTION ON MERCURY  2017年7月 

     詳細を見る

  • Implementation of phase down of dental amalgam use 招待

    小川 祐司

    WHO WESTERN PACIFIC REGIONAL WORKSHOP HEALTH SECTOR INVOLVEMENT IN IMPLEMENTATION OF THE MINAMATA CONVENTION ON MERCURY,  2017年6月 

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  • Evaluation for Brief tobacco interventions (5As and 5Rs) 招待

    小川 祐司

    WHO training oral health professionals in tobacco cessation  2017年3月 

     詳細を見る

  • How we should do for phasing-down use of dental amalgam 招待

    小川 祐司

    WHO EASTERN MEDITERRAEAN REGIONAL WORKSHOP OF HEALTH SECTOR INVOLVEMENT IN THE IMPLEMENTATION OF THE MINAMATA CONVENTION ON MERCURY  2016年12月 

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  • WHO Oral Health Survey Basic Method 5th edition 招待

    小川 祐司

    WHO Calibration Workshop for Oral Health Survey  2016年8月 

     詳細を見る

  • Improve Population Oral Health by Targeting NCD Common Risk Factors 招待

    小川 祐司

    The 38th Asia Pacific Dental Congress  2016年6月 

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  • NCD common risk factor approach for oral health promotion Integrated oral health and NCD prevention and control- WHO perspective- 招待

    小川 祐司

    The 94th General Session of the International Association for Dental Research  2016年6月 

     詳細を見る

  • Strategies for oral disease prevention and health promotion - WHO perspectives 招待

    小川 祐司

    The 12th International Conference of Asian Academy of Preventive Dentistry  2016年5月 

     詳細を見る

  • Epidemiology of Early Childhood Caries 招待

    小川 祐司

    WHO Global Consultation on Early Childhood Caries  2016年1月 

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  • Prevention and control of NCD: WHO vision 招待

    小川 祐司

    FDI Annual World Dental Congress  2015年9月 

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  • Strategies for oral disease prevention and health promotion - WHO perspectives 招待

    小川 祐司

    FDI Annual World Dental Congress  2015年9月 

     詳細を見る

  • Global Burden of Oral Disease: Importance of Optimal Oral Health and Self Care 招待

    小川 祐司

    FDI Annual World Dental Congress  2015年9月 

     詳細を見る

  • Issues and initiatives of emerging countries in preparation for entering the aging society 招待

    小川 祐司

    World Congress 2015 -Dental care and oral health for healthy longevity in an aging society  2015年3月 

     詳細を見る

  • Global Oral Health- Strengthening of oral health in chronic conditions policies - the WHO approach 招待

    小川 祐司

    WHOCC Global Oral Health Seminar  2015年1月 

     詳細を見る

  • WHO coordinating the global efforts to improve oral health through primary health care 招待

    小川 祐司

    15th Kuwait Association for Dental Research Conference  2015年1月 

     詳細を見る

  • Strengthening of oral health in chronic conditions policies - the WHO approach 招待

    小川 祐司

    11th Asian Academy of Preventive Dentistry  2014年9月 

     詳細を見る

  • Oral Health in School Health & Nutrition

    小川 祐司

    The 3rd Annual Training Course on School Health and Nutrition Programmes in Asia  2013年12月 

     詳細を見る

  • Caries control in elderly

    小川 祐司

    International Dental Conference on Caries control throughout life in Asia  2013年11月 

     詳細を見る

  • Mouthrinse, opportunity for caries control in children and elderly

    小川 祐司

    J&J Antimicrobial fluoride mouthrinse for caries control throughout life  2013年11月 

     詳細を見る

  • Population Approaches to Periodontal Health

    小川 祐司

    9th World Congress of Preventive Dentistry  2013年10月 

     詳細を見る

  • School based Fluoride Mouth Rinsing Program for Caries Control 招待

    小川 祐司

    J&J School Rinsing Program: Improve Oral Health for School Children  2013年9月 

     詳細を見る

  • Oral Health Promoting in Schools 招待

    小川 祐司

    7th Asian Conference of Oral Health Promotion for School Children  2013年9月 

     詳細を見る

  • Geriatric component and its sequence in the dental curriculum 招待

    小川 祐司

    The 1st ASEAN Network Meeting on Geriatric Dental Curriculum  2013年8月 

     詳細を見る

  • Dental Caries in the Regional and Global Set-up and Caries Control WHO Perspective 招待

    小川 祐司

    J&J Caries Symposium  2013年5月 

     詳細を見る

  • Importance of Oral Health Promotion for Elderly - integration between oral and general health 招待

    小川 祐司

    1st Medan International Prosthodontic Scientific Meeting  2012年8月 

     詳細を見る

  • Prevention of Oral Diseases for a Dependent Elderly 招待

    小川 祐司

    International Symposium in Geriatric Dentistry “Oral Health Care and Quality of Life in the elderly”  2012年5月 

     詳細を見る

  • Fluoride Mouthrinse Programme to promote school dental health 招待

    小川 祐司

    6th Asian Conference of Oral Health Promotion for School Children  2011年11月 

     詳細を見る

  • General and Oral Health for the Elderly Population 招待

    小川 祐司

    Indonesian Dental Public Health Meeting  2011年11月 

     詳細を見る

  • School based Fluoride Mouth Rinse Programme public health perspectives -Japanese experience-. 招待

    小川 祐司

    Effective Use of Fluoride in Asia  2011年3月 

     詳細を見る

  • General Health and Oral Health for the elderly populations 招待

    小川 祐司

    Chulalongkorn University 70th Anniversary Celebration  2010年8月 

     詳細を見る

  • Health and Oral Health of the Asian Older Population- Challenges and Vision for the Future- 招待

    小川 祐司

    9th International Conference for Asian Academy of Preventive Dentistry  2009年11月 

     詳細を見る

  • Oral health through health promoting schools 招待

    小川 祐司

    The Asian Conference of Oral Health Promotion for School Children  2009年9月 

     詳細を見る

  • The WHO Direction for Oral Health 招待

    小川 祐司

    The 8th Asian Academy of Preventive Dentistry  2008年11月 

     詳細を見る

  • The needs for the guide-line of the Asian Fluoride Uses 招待

    小川 祐司

    28th Myanmar Dental Conference  2008年1月 

     詳細を見る

  • The needs for the guide-line of the Asian Fluoride Uses 招待

    小川 祐司

    Korean Academy of the Clinical Preventive Dentistry  2007年11月 

     詳細を見る

  • Oral Health through Health Promoting Schools 招待

    小川 祐司

    The 4th Asian Conference of Oral Health Promotion for School Children  2007年9月 

     詳細を見る

▶ 全件表示

共同研究・競争的資金等の研究

  • 糖尿病患者の脳梗塞リスクに対する抗菌的歯周治療の有用性に関するランダム化比較試験

    研究課題/領域番号:20K10291  2020年4月 - 2023年3月

    日本学術振興会  科学研究費助成事業 基盤研究(C)  基盤研究(C)

    小川 祐司, 山田 貴穂, 濃野 要, 皆川 久美子

      詳細を見る

    担当区分:研究代表者 

    配分額:4030000円 ( 直接経費:3100000円 、 間接経費:930000円 )

    researchmap

  • 2型糖尿病患者のCKD病態に対する抗菌的歯周治療の有用性に関する無作為化比較試験

    2011年4月 - 2014年3月

    科学研究費  基盤研究(C) 

    小川 祐司

      詳細を見る

    担当区分:研究代表者  資金種別:競争的資金

    researchmap

  • 2型糖尿病患者の抗動脈硬化に対する抗菌的歯周治療の有用性に関する無作為化比較試験

    2008年4月 - 2011年3月

    科学研究費  基盤研究(C) 

    小川 祐司

      詳細を見る

    担当区分:研究代表者  資金種別:競争的資金

    researchmap

  • 抗インシュリン作用改善に対する抗菌的歯周治療の長期有用性に関する無作為化比較試験

    2004年4月 - 2007年3月

    科学研究費  若手研究(B) 

    小川 祐司

      詳細を見る

    担当区分:研究代表者  資金種別:競争的資金

    researchmap

その他研究活動

  • 日本口腔衛生学会認定医

    2010年12月
    -
    現在

     詳細を見る

 

担当経験のある授業科目(researchmap)

  • 地域口腔保健学

    機関名:九州歯科大学

     詳細を見る

  • 衛生学

    機関名:新潟大学

     詳細を見る

  • 予防歯科学

    機関名:新潟大学

     詳細を見る

  • 国際保健学

    機関名:東京歯科大学

     詳細を見る

  • 国際医療人育成学

    機関名:鹿児島大学歯学部

     詳細を見る

  • う蝕学

    機関名:新潟大学

     詳細を見る

  • 国際口腔保健学

    機関名:新潟大学

     詳細を見る

▶ 全件表示

担当経験のある授業科目

  • 口腔保健福祉学研究ベーシックコース

    2022年
    -
    現在
    機関名:新潟大学

  • 生命医療科学総論

    2021年
    -
    現在
    機関名:新潟大学

  • 実践医学統計演習IIA

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健科学研究発表演習I

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健学演習IIA

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔疫学IIA

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健科学特定研究I

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健科学研究発表演習II

    2021年
    -
    現在
    機関名:新潟大学

  • 臨床歯学コースワーク(ベーシック国際口腔保健学コースI)

    2021年
    -
    現在
    機関名:新潟大学

  • エクスターンシップ

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔疫学IB

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健学演習IB

    2021年
    -
    現在
    機関名:新潟大学

  • 口腔保健福祉学特定研究

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健学演習IIB

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔疫学IA

    2021年
    -
    現在
    機関名:新潟大学

  • 臨床歯学コースワーク(ベーシック国際口腔保健学コースII)

    2021年
    -
    現在
    機関名:新潟大学

  • 実践統計学べ-シックコース

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健科学特定研究II

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔保健学演習IA

    2021年
    -
    現在
    機関名:新潟大学

  • 国際口腔疫学IIB

    2021年
    -
    現在
    機関名:新潟大学

  • 齲蝕学

    2020年
    -
    現在
    機関名:新潟大学

  • 実践医学統計演習ⅠA

    2020年
    -
    現在
    機関名:新潟大学

  • 歯科衛生学実習Ⅱ

    2019年
    -
    現在
    機関名:新潟大学

  • 国際口腔疫学ⅡA

    2018年
    機関名:新潟大学

  • ベーシック実践統計学演習ⅡA

    2018年
    機関名:新潟大学

  • 実践統計学べ-シックコース

    2018年
    機関名:新潟大学

  • 国際口腔保健学演習ⅠA

    2018年
    機関名:新潟大学

  • 国際口腔保健学演習ⅡA

    2018年
    機関名:新潟大学

  • 国際口腔保健科学研究発表演習Ⅰ

    2018年
    機関名:新潟大学

  • ベーシック実践統計学演習ⅠA

    2018年
    機関名:新潟大学

  • 国際歯科保健医療学入門

    2017年
    -
    現在
    機関名:新潟大学

  • 衛生学

    2013年
    -
    現在
    機関名:新潟大学

  • 臨床予備実習

    2013年
    機関名:新潟大学

  • 衛生学・公衆衛生学

    2011年
    -
    現在
    機関名:新潟大学

  • 社会調査法

    2011年
    -
    2014年
    機関名:新潟大学

  • う蝕学

    2009年
    -
    2018年
    機関名:新潟大学

  • 実践統計学べーシックコース

    2009年
    機関名:新潟大学

  • 早期臨床実習Ⅱ

    2008年
    -
    2013年
    機関名:新潟大学

  • 予防歯科学

    2007年
    -
    現在
    機関名:新潟大学

  • 予防歯科学実習

    2007年
    -
    現在
    機関名:新潟大学

  • 医療統計学

    2007年
    -
    2010年
    機関名:新潟大学

▶ 全件表示