Updated on 2024/03/28

写真a

 
ONO Kazuhiro
 
Organization
Academic Assembly Institute of Medicine and Dentistry SHIGAKU KEIRETU Professor
Faculty of Dentistry Department of Oral Health and Welfare Professor
Graduate School of Medical and Dental Sciences Oral Health and Welfare Science Oral Health and Welfare Professor
Title
Professor
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Degree

  • 歯学博士 ( 1990.3   新潟大学 )

Research Interests

  • 口唇口蓋裂

  • Cleft Lip and Palate

Research Areas

  • Life Science / Medical biochemistry

  • Life Science / Surgical dentistry

  • Humanities & Social Sciences / Educational technology

Research History (researchmap)

  • - 新潟大学医歯学総合研究科 助教授(口腔生命科学専攻、口腔健康科学講座 顎顔面口腔外科学分野)

    2001

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  • - Associate Professor, Niigata University

    2001

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  • Niigata University   Faculty of Dentistry

    2000 - 2001

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  • Associate Professor, Faculyt of Dentistry,

    2000 - 2001

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  • Niigata University   Faculty of Dentistry

    1999 - 2000

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  • Lecture, Faculyt of Dentistry, Niigata

    1999 - 2000

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  • Niigata University   Faculty of Dentistry

    1990 - 1999

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  • Assistant Professor, Faculyt of Dentistry,

    1990 - 1999

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  • Niigata University

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  • Graduate School of Medical and Dental Sciences

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  • Niigata University Graduate School of Medical and Dental Sciences Master's Program of Oral Health and Welfare Science   Professor

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  • University

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Research History

  • Niigata University   Faculty of Dentistry School of Oral Health and Welfare   Professor

    2010.5

  • Niigata University   Graduate School of Medical and Dental Sciences Master's Program of Oral Health and Welfare Science Dental Educational Research Development   Professor

    2010.5

  • Niigata University   Faculty of Dentistry School of Oral Health and Welfare   Professor

    2005.4 - 2010.4

  • Niigata University   Graduate School of Medical and Dental Sciences Oral Life Science Oral Health Science   Associate Professor

    2001.4 - 2005.3

  • Niigata University   Faculty of Dentistry School of Dentistry   Associate Professor

    2000.5 - 2001.3

  • Niigata University   Faculty of Dentistry   Lecturer

    1999.2 - 2000.4

  • Niigata University   Faculty of Dentistry   Research Assistant

    1990.4 - 1999.1

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Education

  • Niigata University   歯学研究科

    - 1990

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    Country: Japan

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  • Niigata University   Graduate School, Division of Dental Research

    - 1990

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Professional Memberships

  • 日本口腔外科学会

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  • アジア口腔顎顔面外科学会(Asian Association of Oral and Maxillofacial Surgeons)

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  • 日本顎変形症学会

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  • 歯科基礎医学会

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  • 日本顎関節学会

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  • 日本口腔科学会

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  • 日本口蓋裂学会

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  • 日本小児口腔外科学会

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  • 国際口腔顎顔面外科学会(International Association of Oral and Maxillofacial Surgeons)

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  • 日本人類遺伝学会

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  • 新潟歯学会

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  • JAPANESE DENTAL EDUCATION ASSOCIATION

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  • Japan Association for College and University Education

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Papers

  • The Effectiveness of Online PBL in Learning Problem-Solving Skills : A Comparison with Face-to-Face PBL Using Direct Assessment

    ONO Kazuhiro, SAITO Yugo, MATSUSHITA Kayo

    23 ( 23 )   71 - 90   2023.4

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    Language:Japanese   Publisher:Center for the Studies of Higher Education, Nagoya University  

    This study clarifies the effectiveness of online Problem-Based Learning (PBL) by comparing it with face-to-face PBL, targeting students in Department Y of Faculty X at Niigata University, who had been studying the field of oral health and welfare through a PBL-based curriculum. We compared the degree of acquisition of problem-solving skills between 23 second-year students (online group) who had conducted online PBL in 2020 and 18 second-year students (face-to-face group) who had conducted face-to-face PBL in 2019. As an assessment tool, we used the modified Triple Jump, a performance assessment developed to directly assess problemsolving skills, and examined the results of the assessment conducted at the end of the first semester of the second year. Additionally, to infer students’ learning motivation, we also examined their approach to PBL and class satisfaction using a questionnaire. The results showed that there was no difference in the degree of acquisition of problem-solving skills, the way students engaged in PBL, or their level of class satisfaction in the online group compared with the faceto- face group. We believe that online PBL is as effective as face-toface PBL in learning problem-solving skills and in cultivating motivation for learning.

    DOI: 10.18999/njhe.23.71

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  • 専門教育で身につけた問題解決スキルの汎用性の検討―遠い転移に着目して―

    小野和宏, 松下佳代, 斎藤有吾

    日本教育工学会論文誌   47 ( 1 )   27 - 46   2023

  • Occlusal Evaluation Using Modified Huddart and Bodenham Scoring System Following 2-Stage Palatoplasty With Hotz Plate: A Comparison Among 3 Different Surgical Protocols. International journal

    Andrea Rei Estacio Salazar, Yasumitsu Kodama, Ryutaro Yuki, Rei Ominato, Takahiro Nagai, Momoko Watanabe, Akane Yamada, Ryota Kobayashi, Kaya Ichikawa, Jun Nihara, Akihiko Iida, Kazuhiro Ono, Isao Saito, Ritsuo Takagi

    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association   10556656221093293 - 10556656221093293   2022.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    OBJECTIVE: This study aimed to determine if the change in technique of soft palate closure or timing of hard palatal repair induced occlusal changes in patients with complete unilateral cleft lip and palate (CUCLP). DESIGN: Retrospective study. SETTINGS: A medical and dental hospital in Japan. SUBJECTS: A total of 96 patients with CUCLP treated with 2-stage palatoplasty were included in the study and categorized into 3 groups (G1, G2, and G3) according to the protocol used. INTERVENTIONS: G1 underwent soft palate repair using Perko method at 1.5 years of age and hard palate repair using vomer flap procedure at 5.5 years of age. Furlow method was used for soft palate repair in G2 at 1.5 years of age and hard palate repair using vomer flap procedure at 5.5 years of age. The Furlow method was used to repair the soft palate in G3 at 1.5 years of age and vomer flap procedure was used to repair the hard palate at 4 years of age. MAIN OUTCOME MEASURES: Two evaluators assessed the dental arch relationship using the modified Huddart/Bodenham (mHB) index on 2 separate occasions. RESULTS: Intra- (intraclass correlation coefficient [ICC]: 0.962) and inter-examiner (ICC: 0.950) reliability showed very good agreement. The frequency of crossbite present in the major and minor segments gradually decreased with each change in protocol. Mean segmental scores showed no significant difference between 3 protocols (P > .05). Good inter-arch alignment occurred with all 3 surgical protocols (G1:82.6%, G2:89.8%, and G3:91.7%). CONCLUSIONS: There was no significant difference in the dental arch relationship outcomes between the 3 surgical protocols. The dentition status was comparable with all surgical protocols, even after the changes.

    DOI: 10.1177/10556656221093293

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  • 二段階口蓋形成手術法における幼児期前期の言語管理に関する検討 口蓋化構音と硬口蓋残遺裂の関連性にもとづいて

    大湊 麗, 小野 和宏, 児玉 泰光, 結城 龍太郎, 永井 孝宏, 小林 亮太, 小林 孝憲, 飯田 明彦, 濃野 要, 宮田 昌幸, 小林 正治, 齋藤 功, 高木 律男, 冨原 圭

    日本口蓋裂学会雑誌   47 ( 1 )   20 - 29   2022.4

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    Language:Japanese   Publisher:(一社)日本口蓋裂学会  

    当院の二段階口蓋形成手術法では、軟口蓋形成術をFurlow法により1歳半に、硬口蓋閉鎖術を鋤骨弁により4歳に施行している。軟口蓋形成術後の硬口蓋残遺裂には硬口蓋閉鎖床を装着しているが、この間の言語機能の獲得には否定的な影響が懸念されやすい。本研究では、当院の治療体系における口蓋化構音の発現要因を明らかにし、口蓋化構音の発現を予防することを目的として、まず、軟口蓋形成術後の1歳半から硬口蓋閉鎖術前の4歳までを幼児期前期とし、片側完全唇顎口蓋裂16例の幼児期前期の言語発達過程でみられた言語症状を回顧的に評価し、良好群、口蓋化構音群(以下、口蓋化群)、不良群の3群に類型化した。そして、類型化した群ごとに、言語機能の獲得状況と硬口蓋残遺裂を含めた上顎歯槽弓形態の関連性について検討した。その結果、口蓋化群の2歳の硬口蓋残遺裂後端の位置に関連性が示され、硬口蓋残遺裂後端や軟口蓋からの漏れを補おうとする舌の誤学習が、口蓋化構音の発現に影響を与えている可能性が推察された。また、得られた結果にもとづき、言語機能をできる限り向上させるため、幼児期前期の言語管理の進め方について再考した。(著者抄録)

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  • Evaluation of the 5-Year-Olds’ Index after Two-Stage Palatoplasty for Unilateral Cleft Lip and Palate:: Influence of Soft Palatoplasty and Timing of Hard Palate Closure

    YUKI Ryutaro, KODAMA Yasumitsu, Andrea Rei Estacio Salazar, OMINATO Rei, NAGAI Takahiro, YAMADA Akane, KOBAYASHI Ryota, ICHIKAWA Kaya, NIHARA Jun, KATO Junya, ASAHITO Toshikazu, IIDA Akihiko, ONO Kazuhiro, SAITO Isao, TAKAGI Ritsuo

    Journal of Japanese Cleft Palate Association   47 ( 3 )   200 - 209   2022

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    Language:Japanese   Publisher:Japanese Cleft Palate Association  

    The Department of Oral and Maxillofacial Surgery at Niigata University Medical and Dental Hospital (“our department”) has been treating cleft lip and palate with a team approach and consistent management system since its establishment in 1974. We have been using the two-stage palatoplasty with Hotz plate (“two-stage method”) since 1983. The surgical protocol has been changed twice in the past in order to improve speech outcomes. Although we have reported the improvement of treatment results based on speech evaluation and morphological analysis of the maxillary dentition model, we have not examined the results from the perspective of occlusion. In this study, we evaluated the occlusal relationship using the 5-year-olds’ index, and examined the validity of the two surgical protocol revisions.
    <br>In this study, 97 patients with unilateral cleft lip and palate treated at our department were included. The 97 cases were classified according to the technique used for repairing the soft palate and the timing of hard palate closure:
    <br>(1) Group P+5: 23 patients who received soft palate closure by the Perko method at 1.5 years of age and hard palate closure with Vomer flap surgery at 5.5 years of age between 1996 and 2009,
    <br>(2) Group F+5: 49 patients who received soft palate closure by the modified Furlow method at 1.5 years of age for repair of the soft palate and hard palate closure with Vomer flap at 5.5 years of age between 1996 and 2009, and
    <br>(3) Group F+4: 25 patients who received soft palate closure by the modified Furlow method at 1.5 years of age and hard palate closure with Vomer flap at 4 years of age between 2010 and 2017.
    <br>The results of the occlusion evaluation using the 5-year-olds’ index were as follows: 2.65 (P+5 group), 2.77 (F+5 group), and 2.80 (F+4 group), and there were no significant differences among the groups by the t-test.
    <br>These results indicate that the change in surgical protocol at our department has helped improve the therapeutic results of the two-stage method with Hotz plate, since a good occlusal relationship was maintained among the groups, which is known to be a characteristic of the two-stage method, in addition to the reported improvement in speech outcomes.

    DOI: 10.11224/cleftpalate.47.200

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  • 卒前の総合模型実習と診療参加型臨床実習が臨床研修開始時の歯科臨床能力に及ぼす効果

    秋葉 奈美, 秋葉 陽介, 小野 和宏, 長澤 麻沙子, 藤井 規孝, 魚島 勝美

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   40回   58 - 58   2021.11

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  • 新潟大学医歯学総合病院における新診療体制後の口唇口蓋裂患者動向調査

    児玉 泰光, 小林 亮太, 山田 茜, Salazar Andrea Rei Estacio, 結城 龍太郎, 永井 孝宏, 大湊 麗, 池田 順行, 市川 佳弥, 丹原 惇, 新美 奏恵, 若槻 華子, 宮田 昌幸, 小野 和宏, 齋藤 功, 小林 正治, 高木 律男

    日本口蓋裂学会雑誌   46 ( 2 )   133 - 133   2021.4

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    Language:Japanese   Publisher:(一社)日本口蓋裂学会  

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  • <Educational Practice Report>Direct Assessment of Long-Term Learning Outcomes in the PBL Curriculum: Based on a Longitudinal Study of Performance Assessment at the Niigata University's Faculty of Dentistry

    Ono, Kazuhiro, Matsushita, Kayo, Saito, Yugo

    Kyoto University Researches in Higher Education   26   1 - 12   2020.12

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    Language:Japanese   Publishing type:Research paper (bulletin of university, research institution)  

    The purpose of this study was to examine the transformation of students' problem-solving ability, one of the higher-order skills, by performance assessment at the educational program level. The subjects were 82 students at the Niigata University's Faculty of Dentistry, who had studied under our problem-based learning (PBL) curriculum. For direct assessment of problem-solving ability, we used modified triple jump (MTJ) which had been developed as an assessment tool for our PBL program. We performed MTJ at three different time points during the second and the third year and assessed problem-solving ability of the students longitudinally. At the same time, we also examined the difficulty level of the three performance tasks used in MTJ from two aspects, conceptual contents and student perceptions. As a result, the assessment scores of MTJ improved significantly with moderate to large effect size along with their experience of PBL. The performance tasks used in MTJ became more complex along with the accumulation of learning contents in the curriculum, and student perceptions of difficulty level of the performance tasks showed similar results. In conclusion, the reason for the score improvement was not because the tasks of MTJ became easier but because problem-solving ability of the students improved. By considering the difficulty level of the performance tasks, we were able to assess the transformation of students' problem-solving ability at the educational program level from the results of embedded performance assessment in PBL courses.

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    Other Link: http://hdl.handle.net/2433/261201

  • <Articles by the Center Staff and Research Fellows>Combining Course- and Program-Level Outcomes Assessments through Embedded Performance Assessments at Key Courses: A Proposal Based on the Experience from a Japanese Dental Education Program

    Matsushita, Kayo, Ono, Kazuhiro, Saito, Yugo

    Kyoto University Researches in Higher Education   26   51 - 64   2020.12

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    This paper addresses how to combine course- and program-level assessments and presents a new assessment method illustrated by a case of dental education program in Japan. Performance assessments are considered effective for evaluating knowledge integration and higher-order skills, while placing a burden on faculty, hence their feasibility as the program-level assessment is regarded lower than standardized tests or questionnaire surveys. We have developed several performance assessments at the course level, such as Modified Triple Jump for the PBL course. Based on this experience, we propose Pivotal Embedded Performance Assessment (PEPA) as a method for combining assessment at the course and program levels. The method limits the range of performance assessment to key courses directly linked to program goals and placed at the critical juncture points of curriculum, while entrusting the assessment of other courses to expert judgment of individual teachers. PEPA consists of the following procedures: systematization of curriculum and selection of key courses; design and implementation of performance assessments by a faculty team; setting passing criteria with incorporating the function of formative assessment; certifying the completion of the degree program. PEPA thus enables maintaining assessment feasibility and compatibility with a credit system, while ensuring assessment validity and reliability.

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    Other Link: http://hdl.handle.net/2433/261206

  • 異なる二段階口蓋形成手術法を施行した片側性唇顎口蓋裂患児の5-Year-Olds' Indexによる咬合評価

    結城 龍太郎, 児玉 泰光, Estacio Salazar Andrea Rei, 大湊 麗, 永井 孝宏, 山田 茜, 小林 亮太, 市川 佳弥, 丹原 惇, 加藤 純也, 朝日藤 寿一, 飯田 明彦, 小野 和宏, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   45 ( 2 )   128 - 128   2020.5

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    Language:Japanese   Publisher:(一社)日本口蓋裂学会  

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  • Endurance measurement of hyoid muscle activity and hyoid-laryngeal position during tongue lift movement. Reviewed International journal

    Yukako Sunada, Jin Magara, Takanori Tsujimura, Kazuhiro Ono, Makoto Inoue

    Journal of oral rehabilitation   47 ( 8 )   967 - 976   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Tongue lift movement (TLM) is used as a therapy to improve tongue pressure against the hard palate for dysphagic patients. OBJECTIVE: The present study aimed to characterize the time-dependent endurance changes in hyoid muscle activity and hyoid-laryngeal displacement during TLM in different ways. METHODS: Sixteen young healthy volunteers were instructed to perform TLM at maximum effort (100%) against the anterior and posterior parts of the hard palate using a balloon-type tongue pressure instrument, followed by a 10-second recording during anterior 80% TLM, anterior 100% TLM, posterior 80% TLM and posterior 100% TLM with visual feedback. Electromyography (EMG) of suprahyoid (S-Hyo) and infrahyoid (I-Hyo) muscles and videofluorography were simultaneously recorded. To evaluate temporal changes, the recording period was divided into three substages: early, middle and late. Tongue pressure, integrated EMG (iEMG), power frequency of EMG burst and hyoid-laryngeal position were compared among the conditions (80% vs 100%, anterior vs posterior and early vs middle vs late). RESULTS: Tongue pressure was stably maintained for 10 seconds in all conditions. S-Hyo iEMG and I-Hyo iEMG were significantly greater at 100% than at 80%, while no significant difference was observed between positions. S-Hyo iEMG and I-Hyo iEMG significantly increased at the late stage, while power frequency of EMG burst gradually decreased. Significant temporal changes in laryngeal elevation were observed only in posterior 100% TLM. CONCLUSION: The current results suggested that isometric posterior TLM may be more useful compared with anterior TLM in clinical situations for dysphagic patients to elevate the hyolaryngeal complex.

    DOI: 10.1111/joor.12988

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  • Properties of hyoid muscle contraction during tongue lift measurement. Reviewed International journal

    Naomi Koshi, Jin Magara, Shogo Sakai, Takanori Tsujimura, Kazuhiro Ono, Makoto Inoue

    Journal of oral rehabilitation   47 ( 3 )   332 - 338   2020.3

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    BACKGROUND: Tongue lift movement (TLM) task is considered a treatment strategy in dysphagic patients. However, there is no evidence of effect of sustained tongue movements on the related muscle contraction. OBJECTIVES: The present study aimed to characterise the properties and time-dependent changes of the electromyographic (EMG) features of suprahyoid muscles during TLM. METHODS: Twenty young healthy volunteers were instructed to perform TLM at maximum effort in either the anterior or the posterior position, during measurement of tongue pressure for 7 s. Supra- (S-hyo) and infra-hyoid (I-hyo) EMGs were recorded. The area and power frequency of EMG burst and the area under the curve of tongue pressure were compared among the conditions: trials (1st, 2nd vs 3rd trials); anterior vs posterior TLM; and early vs late 3 s of each trial. RESULTS: There was no difference in the tongue pressure among trials or between the early and late 3 s. Anterior tongue pressure was significantly higher than posterior tongue pressure (P < .001). The area of I-hyo EMG burst was significantly larger (P = .044), and the power frequency of I-hyo EMG burst was significantly smaller (P = .042) during posterior TLM than anterior TLM. A significant difference in the power frequency of both EMG bursts was observed between early and late stages during both anterior (P < .05) and posterior (P < .01) TLM. CONCLUSION: Hyoid muscles may compensate for rapid fatigue of the tongue muscle to maintain tongue pressure by changing their activity pattern during tongue pressure generation.

    DOI: 10.1111/joor.12894

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  • 舌挙上運動時における舌骨筋の機能特性

    古志 奈緒美, 真柄 仁, 辻村 恭憲, 小野 和宏, 井上 誠

    新潟歯学会雑誌   49 ( 2 )   77 - 77   2019.12

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  • ビスフォスフォネート製剤を内服する顎変形症の1例

    池田 順行, 小山 貴寛, 小玉 直樹, 高木 律男, 小野 和宏, 阿部 裕子

    日本形成外科学会会誌   39 ( 8 )   409 - 409   2019.8

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  • eラーニングを活用した反転授業の試み

    平原 三貴子, 岩瀬 陽子, 大内 章嗣, 小野 和宏, 前田 健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   38回   122 - 122   2019.6

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  • 本学における「歯学研究演習」を履修して

    高島 大輔, 高橋 士穂, 佐伯 万騎男, 藤井 規孝, 魚島 勝美, 前田 健康, 小野 和宏

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   38回   162 - 162   2019.6

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  • 二段階口蓋形成術施行片側性唇顎口蓋裂患児の咬合評価(第3報) 術式と術期の異なる2群間での比較

    児玉 泰光, 結城 龍太郎, Estacio Salazar Andrea Rei, 大湊 麗, 永井 孝宏, 渡部 桃子, 山田 茜, 市川 佳弥, 丹原 惇, 飯田 明彦, 小野 和宏, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   44 ( 2 )   135 - 135   2019.4

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  • 二段階口蓋形成術施行片側性唇顎口蓋裂患児の咬合評価(第1報) 軟口蓋形成術式 Perko法とFurlow法での比較

    結城 龍太郎, 児玉 泰光, Estacio Salazar Andrea Rei, 大湊 麗, 永井 孝宏, 渡部 桃子, 山田 茜, 市川 佳弥, 丹原 惇, 飯田 明彦, 小野 和宏, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   44 ( 2 )   134 - 134   2019.4

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  • 二段階口蓋形成術施行片側性唇顎口蓋裂患児の咬合評価(第2報) 硬口蓋閉鎖時期 5歳半と4歳での比較

    サラザール・アンドレア・レイ・エスタシオ, 児玉 泰光, 結城 龍太郎, 大湊 麗, 永井 孝宏, 渡部 桃子, 山田 茜, 市川 佳弥, 丹原 惇, 飯田 明彦, 小野 和宏, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   44 ( 2 )   134 - 134   2019.4

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  • <Educational Practice Reports>Factors for "Assessment as Learning" in Modified Triple Jump as Performance Assessment of PBL Reviewed

    Ono, Kazuhiro, Saito, Yugo, Matsushita, Kayo

    Kyoto University Researches in Higher Education   24   35 - 44   2018.12

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    An assessment of students' performance in active learning process is highly time consuming and requires a considerable effort. As a result, the so-called "assessment fatigue" is a concern among teachers. However, since the assessment itself could be a powerful learning tool for students and if the teachers recognized that it could lead to their growth, they would consider this challenging task as worthwhile. We have developed and have been using a modified triple jump (MTJ) as an assessment tool for our PBL program. In this report, we tried to find out the factors that make this performance assessment function as learning for students based on their perceptions. The subjects were 64 students at the Faculty of Dentistry of Niigata University who experienced our MTJ three times during their undergraduate education program. A questionnaire survey was conducted after each assessment and description contents were analyzed by text mining. As a result of the content analysis, we concluded that MTJ encourages students to learn deeply and to reflect on their own learning. Furthermore, the results suggest that the effect of MTJ as "assessment as learning" depends on the real-world relevance of their learning tasks and the usefulness of acquired knowledges. Other important factors were appropriate disclosure of the assessment criteria along with students' skill of self-assessment and individual/continuous descriptive feedback from teachers.

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    Other Link: http://hdl.handle.net/2433/241248

  • 顎矯正手術を行ったビスフォスフォネートを内服する顎変形症の1例

    池田 順行, 小野 和宏, 阿部 裕子, 丹原 惇, 齋藤 功, 高木 律男

    新潟歯学会雑誌   48 ( 2 )   91 - 96   2018.12

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    ビスフォスフォネート(BP)製剤関連顎骨壊死(BRONJ)は広く認知されるようになってきたが、BPの投与を受ける患者に対して顎矯正手術を行った報告は少ない。今回われわれは、BPを内服する患者に対して顎矯正手術を行ったので報告する。患者は16歳男性で不正咬合を主訴に当科を受診した。骨格性下顎前突症の診断となり、顎矯正手術を計画したが、術前矯正治療終了後に多発性硬化症の診断に至り、ステロイドの内服治療が開始され、ステロイド性骨粗鬆症の予防のためにBPの内服も開始された。治療により多発性硬化症の症状の出現はなく、ステロイドは減量されていった。19歳時に、BPを6ヵ月間休薬し、Le Fort I型骨切り術と下顎枝矢状分割法による顎矯正手術を行って、9ヵ月後にプレート除去を行い、BPを再開した。周術期は感染に留意し、BRONJの発症はなかった。顎矯正手術後2年が経過した現在も経過観察中であるが、異常経過は認めていない。(著者抄録)

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  • 二段階口蓋形成手術法における硬口蓋閉鎖時期の検討 ナゾメーターによる分析 Reviewed

    大湊 麗, 小野 和宏, 児玉 泰光, 小山 貴寛, 飯田 明彦, 永田 昌毅, 高木 律男

    新潟歯学会雑誌   48 ( 1 )   17 - 21   2018.6

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    新潟大学顎顔面口腔外科では1983年より二段階口蓋形成手術法を施行しており、顎発育による分析から、2010年より硬口蓋閉鎖時期を5歳半から4歳へ早期移行した。これまで、硬口蓋閉鎖時期の早期移行が4歳時から6歳時における言語機能獲得に与える影響について、音声言語の聴覚判定による分析から検討しており、硬口蓋閉鎖術を5歳半に施行した群(晩期群)に比較して4歳に施行した群(早期群)は、5歳時の鼻咽腔閉鎖機能において、良好例の有意な増加がみられ、言語機能獲得に肯定的な結果が示された。本研究では、この聴覚的な臨床データを裏付けるために、ナゾメーターによる分析から再検討した。その結果、5歳時の文章および高圧文のnasalance scoreにおいて、早期群と晩期群の硬口蓋閉鎖床撤去時の間に有意差を認め、音声言語の聴覚判定と整合する結果が示された。顎発育および音声言語の聴覚判定ならびにナゾメーターによる分析を統合すると、当科の二段階口蓋形成手術法における硬口蓋閉鎖時期の妥当性が再確認された。(著者抄録)

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  • 二段階口蓋形成手術法における硬口蓋閉鎖時期の検討 ナゾメーターによる分析

    大湊 麗, 小野 和宏, 児玉 泰光, 小山 貴寛, 飯田 明彦, 永田 昌毅, 高木 律男

    新潟歯学会雑誌   48 ( 1 )   17 - 21   2018.6

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    新潟大学顎顔面口腔外科では1983年より二段階口蓋形成手術法を施行しており、顎発育による分析から、2010年より硬口蓋閉鎖時期を5歳半から4歳へ早期移行した。これまで、硬口蓋閉鎖時期の早期移行が4歳時から6歳時における言語機能獲得に与える影響について、音声言語の聴覚判定による分析から検討しており、硬口蓋閉鎖術を5歳半に施行した群(晩期群)に比較して4歳に施行した群(早期群)は、5歳時の鼻咽腔閉鎖機能において、良好例の有意な増加がみられ、言語機能獲得に肯定的な結果が示された。本研究では、この聴覚的な臨床データを裏付けるために、ナゾメーターによる分析から再検討した。その結果、5歳時の文章および高圧文のnasalance scoreにおいて、早期群と晩期群の硬口蓋閉鎖床撤去時の間に有意差を認め、音声言語の聴覚判定と整合する結果が示された。顎発育および音声言語の聴覚判定ならびにナゾメーターによる分析を統合すると、当科の二段階口蓋形成手術法における硬口蓋閉鎖時期の妥当性が再確認された。(著者抄録)

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  • Analysis of Students' Reflections on the Differences between Student Self-Assessment and Teacher Assessment through the Use of a Rubric : Focus on Student Self-Assessment Change in PBL Performance Assessment

    斎藤 有吾, 小野 和宏, 松下 佳代

    大学教育学会誌 = Journal of Japan Association for College and University Education   39 ( 2 )   48 - 57   2017.11

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    A current debate surrounding educational reform focuses on self-assessment abilities. In this research, during the performance assessment of problem-solving abilities, students were asked to assess themselves. We then attempted to promote students' reflection on the reasons behind the differences between self- and teacher assessment. Using both quantitative and qualitative data, we examined how reflection affected students' self-assessment. The results indicated that students increased their awareness of the meaning of the rubric descriptors and what was required by the tasks. Finally, we discovered that students were likely to determine their own weaknesses based on the differences from the teacher assessment and create an in-depth reflection that leads to further learning. This type of "assessment as learning" could also indicate a promising direction for utilizing rubrics in students' learning.

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  • Validation of Optimal Timing for Hard Palate Closure in Two-stage Palatoplasty:―Evaluation of Speech Outcome―

    OMINATO Rei, ONO Kazuhiro, IIDA Akihiko, KODAMA Yasumitsu, KOYAMA Takahiro, NAGATA Masaki, TAKAGI Ritsuo

    J.Jpn.Cleft Palate Assoc.   42 ( 3 )   201 - 207   2017.10

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    We have performed two-stage palatoplasty for patients with cleft lips and palates in the Oral and Maxillofacial Surgery Clinic of Niigata University Medical and Dental Hospital since 1983. As a result of evaluating maxillary growth, we have changed the timing of hard palate closure from 5.5 years of age to 4 years of age since 2010. To validate the earlier hard palate closure in our two-stage procedure, we evaluated speech outcome at 4, 5, and 6 years of age. At 5 years of age, the cases with good velopharyngeal function increased significantly and the palatalized articulation was significantly reduced due to the earlier hard palate closure. Based on an evaluation of maxillary growth and speech outcome together, we conclude that earlier hard palate closure is reasonable for our two-stage procedure.

    DOI: 10.11224/cleftpalate.42.201

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  • 診療参加型歯科臨床実習におけるweb公開型電子ポートフォリオの開発と運用

    小田 陽平, 小野 和宏, 藤井 規孝, 小林 正治, 前田 健康

    日本歯科医学教育学会雑誌   33 ( 2 )   65 - 73   2017.8

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    近年、歯学部・歯科大学では技能教育の改善が求められ、診療参加型臨床実習の実践が推奨されている。本学では以前より、学生が直接歯科医療行為に参加する臨床実習を実施しているが、その学習成果、すなわち、現実的な状況で知識や技術を使いこなせる統合的な能力としての「臨床能力」を、いかにして直接評価すべきか対応に苦慮してきた。また、学生が実際の診療の中でどのようなことを感じ、学習し、どのような指導を受けたか、という学習過程そのものが、必ずしも整理された形で実体化されていないという問題点があった。そこで、臨床能力を評価するためのルーブリックを定め、学生の臨床能力を客観性のある到達レベルとして把握するとともに、日々の臨床実習での学習活動を記載するポートフォリオと組み合わせて運用することにより、臨床実習で行っている教育そのものを経時的に記録・評価し、実体化するという発想にいたった。このような背景から電子ポートフォリオの開発と運用を開始したが、学生・教員の受け入れはスムースであった。臨床実習が進むにつれ、ポートフォリオに記載された教員による学生の評価は向上しており、経験を積むことによる学生の臨床能力向上が反映されたものと推察された。以上のことから、臨床実習における電子ポートフォリオの導入は、学生自身の振り返りや教員の学生指導にとって有用であると考えられた。(著者抄録)

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  • 新潟大学歯学部における統合型模型実習の取り組み

    秋葉 奈美, 長澤 麻沙子, 小野 和宏, 前田 健康, 魚島 勝美

    日本歯科医学教育学会雑誌   33 ( 2 )   106 - 114   2017.8

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    本邦では、社会の急速な高齢化に伴い、高度な治療が求められる患者や全身的な疾患を有する患者が増加している。また、患者の意識変化によって、より質の高い治療を求められることが多くなっている結果、臨床実習に協力していただける患者が減少している。このような背景から、学生は限られた患者を対象に臨床技能の習得をし、卒業時には相応の知識と臨床能力を確保しなければならない。この問題を解決するための手段として、新潟大学歯学部では1つの模型の中に様々な病態を具備した6種類のオリジナルの模型を開発し、治療計画立案を含めた統合的な模型実習を導入している。実習は臨床実習直前の5年前期に実施され、基礎模型実習と臨床実習をつなぐと共に、不足する臨床実習を補完する役割を果たす。模型には歯石除去必要部位、抜歯、充填、歯内治療、分割抜歯適応歯および歯冠修復、不良補綴歯、欠損補綴適応部位を含む。学生は診断・治療計画立案から歯科処置までをファントムに装着した模型上で実際の臨床をシミュレートする形で行う。現在、本実習の評価はルーブリックを用いて行っているが、評価方法に関しては今後も継続的に検討する必要がある。実習後の学生アンケートからは実習が有意義なものであったとの回答を得ており、知識や技術を使いこなす統合的な能力の育成に有効であることが示唆された。(著者抄録)

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    Other Link: https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2017&ichushi_jid=J02148&link_issn=&doc_id=20170904280005&doc_link_id=10.24744%2Fjdea.33.2_106&url=https%3A%2F%2Fdoi.org%2F10.24744%2Fjdea.33.2_106&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  • 新潟大学歯学部臨床実習における臨床能力評価

    藤井 規孝, 竹中 彰治, 多部田 康一, 佐藤 直子, 秋葉 奈美, 小田 陽平, 勝見 祐二, 小野 和宏, 前田 健康

    日本歯科医学教育学会雑誌   33 ( 1 )   4 - 11   2017.4

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    歯学教育を改善するために、各大学歯学部・歯科大学においてさまざまな取り組みが行われている。なかでも、診療参加型の臨床実習を充実させることは重視されており、それぞれの歯学部・歯科大学は信頼される歯科医師を輩出するという最も大きな社会的命題を果たすべく努力を続けている。新潟大学歯学部では、卒業生の質の保証を目的に、臨床実習においてACCEPT Projectを立ち上げ、「ACKPIS」と称する方法を用いて学生の臨床能力を評価してきた。ACKPISは診療を自験する学生に対し、どのような専門領域においても必要不可欠となる6つの基本項目を、それぞれの専門処置を評価課題として確認するものである。今回、ACKPISの効果を検証するために、平成28年度の受検生にアンケート調査を行った。ACKPISの基本項目は、ADEAやGDCが提唱する歯科医師に求められるコンピテンシーの中にも該当する記述がみられ、国内外で医師に対して行われている臨床能力評価法同様、診療現場でのフィードバックを含んでいることから、歯学生の臨床能力を評価するために適当であると考えられた。また、アンケート結果から、受検した学生もACKPISの必要性や重要性を認識し、受検方法や合否判定の妥当性を認めていることが明らかになった。以上のことから、ACKPISは臨床実習中の学生の臨床能力を評価するための有用な方法となり得ることが示唆された。(著者抄録)

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  • Cephalometric Evaluation after Two-Stage Palatoplasty Combined with Hotz's plate: A comparative study between modified Furlow's and Widmaier-Perko's methods Reviewed

    Madachi K, Takagi R, Oominato R, Kodama Y, Iida A, Ono K, Asahito T, SAITO I

    Int J Oral Maxillofac Surg   46 ( 5 )   539 - 547   2017

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    DOI: 10.1016/j.ijom.2017.01.009

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  • Correlations of Direct Measures Based on Performance Assessment and Indirect Measures Based on Student Self-report

    SAITO Yugo, ONO Kazuhiro, MATSUSHITA Kayo

    Japan Journal of Educational Technology   40 ( 0 )   157 - 160   2017

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    &lt;p&gt; 近年,大学教育では,学習成果の直接的指標と間接的指標との関連が活発に議論されている.本研究では,ある歯学系のコースのパフォーマンス評価を事例とし,教員の評価と学生の自己評価 (直接評価) と,学生の学生調査用アンケート項目への自己報告 (間接評価) との関連を検討し,そこからそれぞれの評価が担うべき役割と射程を議論する. &lt;/p&gt;

    DOI: 10.15077/jjet.S40078

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  • 学習履歴を教育に活かす 能力を把握して学びを促す 歯科臨床能力の直接評価を中心に

    小野 和宏

    日本歯科医学教育学会雑誌   32 ( 3 )   135 - 136   2016.12

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  • A clinical Investigation of Patients with Submucous cleft Palate:―Speech Outcomes―

    OMINATO Rei, KOBAYASHI Takanori, KODAMA Yasumitsu, KOYAMA Takahiro, IKARASHI Yuki, IIDA Akihiko, ONO Kazuhiro, NAGATA Masaki, TAKAGI Ritsuo

    J.Jpn.Cleft Palate Assoc.   41 ( 3 )   173 - 180   2016.10

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    We investigated speech outcomes in 80 patients with submucous cleft palate assessed by the Oral and Maxillofacial Surgery Clinic and the Speech Clinic in Dentistry at the Niigata University Medical and Dental Hospital from 1982 to 2012. Of the 80 patients, there were 60 patients in the surgically treated group and 20 patients in the non-surgically treated group.&lt;br&gt;The results were as follows:&lt;br&gt;1) In the surgically treated group, the velopharyngeal function evaluated after palatoplasty (an average of 2 years postoperatively) was good (good+fairly good) in 36 patients (63.4%). When we examined the association between age at palatoplasty and velopharyngeal function, the velopharyngeal function evaluated postoperatively was good in almost all of the 1-year-old children, but poor (fairly poor+poor) in more than half of the children over 5 years of age. When we examined the association between mental retardation (MR) and velopharyngeal function, the MR group tended not to have better outcomes than the non-MR group.&lt;br&gt;2) In the non-surgically treated group, there was no clear change before and after treatment.

    DOI: 10.11224/cleftpalate.41.173

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  • 粘膜下口蓋裂の臨床統計的検討(第1報) 診断と病態

    大湊 麗, 小林 孝憲, 児玉 泰光, 小山 貴寛, 五十嵐 友樹, 飯田 明彦, 小野 和宏, 永田 昌毅, 高木 律男

    日本口蓋裂学会雑誌   41 ( 1 )   24 - 30   2016.4

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    新潟大学医歯学総合病院顎顔面口腔外科において1982年から2012年の31年間に粘膜下口蓋裂と診断した84例を対象に、性別、出生時体重、初診時年齢、主訴、来院経路、合併症、Calnanの3徴候、治療内容および母親の出産時年齢について回顧的に検討した。なお、当科の粘膜下口蓋裂の診断基準は軟口蓋の筋層離開とした。その結果、以下の知見を得た。1)性別は男性42例(50.0%)、女性42例(50.0%)であり、性差はみられなかった。2)初診時年齢は生後9日から49歳にわたり、平均4.6歳であった。3)主訴は構音や言語発達などの言語の異常に関する訴えが最も多く、59例(70.2%)であった。4)当科への来院は小児科からの紹介が26例(31.0%)、他院歯科が21例(25.0%)であり、両者で半数以上を占めていた。5)精神発達遅滞の合併は28例(33.3%)にみられた。6)Calnanの3徴候がすべて確認された症例は62例(73.8%)であった。7)当科の初回手術は口蓋形成術とし、口蓋形成術を施行した症例は60例(71.4%)、施行しなかった症例は24例(28.6%)であった。(著者抄録)

    DOI: 10.11224/cleftpalate.41.24

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  • An Analysis of the Learning Processes that Influence Changes in Students' Problem-Solving Abilities in a PBL Course : Integration of Direct and Indirect Assessments at the Course Level

    斎藤 有吾, 小野 和宏, 松下 佳代

    大学教育学会誌 = Journal of Japan Association for College and University Education   37 ( 2 )   124 - 133   2015.11

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  • インプラント治療による上顎洞に関連した合併症の臨床的検討

    池田 順行, 星名 秀行, 小野 和宏, 小玉 直樹, 勝見 祐二, 山田 一穂, 高木 律男

    Japanese Journal of Maxillo Facial Implants   14 ( 2 )   99 - 105   2015.8

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    インプラント治療は近年広く普及してきたが、その一方でさまざまな合併症も生じている。今回われわれは、インプラント治療による合併症を減少させることを目的に、上顎臼歯部に対するインプラント治療後に上顎洞に関連した合併症が生じて当科を受診した6症例を臨床的に検討した。症例の内訳は、歯根型インプラントの上顎洞への迷入が3症例、ブレードインプラントの上顎洞内への穿孔が2症例、サイナスリフトの移植骨への感染が1症例であった。インプラント治療後に症状が発現して受診するまでの期間は2日から17年で、迷入後早期に受診した1症例を除く5症例では少なからず上顎洞炎を発症しており、1年を超えた4症例中の3症例では慢性上顎洞炎に移行し、インプラント材料の摘出に加え上顎洞根治術を行う必要があった。以上より、上顎臼歯部のインプラント治療にあたっては、上顎洞に関連した合併症が生じることを説明するとともに、長期にわたる定期的な経過観察と症状発現時の早期の対応が重要と考えられた。(著者抄録)

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  • Seminar on the Assessment of Cleft Palate Speech::A Report from the Japancleft Committee of the Japanese Cleft Palate Association

    FUJIWARA Yuri, GOTO Masaaki, SUZUKI Keiko, SAITO Isao, SUSAMI Takafumi, ASAHITO Toshikazu, MAKI Kotaro, YOSHIMURA Yoko, SUZUKI Shigehiko, ONO Kazuhiro

    J.Jpn.Cleft Palate Assoc.   40 ( 3 )   248 - 252   2015

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    A seminar on the assessment of cleft palate speech hosted by the Japancleft Committee, Japanese Cleft Palate Association, was held at the University Hospital and the Sanjo Conference Hall, the University of Tokyo on January 31 and February 1, 2015. The purpose of the seminar was to increase awareness of the issues on standardized speech assessment among Japanese speech and language therapists and researchers in the field, and to propose a standardized system which is compatible with international approaches. A training protocol for valid and reliable assessment is to be developed, taking lessons from experiences in the UK and Ireland. Dr. Debbie Sell and Dr. Triona Sweeney, who developed the Cleft Audit Protocol for Speech-Augmented (CAPS-A) and a training package, were invited as lecturers at the seminar. The number of participants was 134, including 67 speech therapists, 57 dentists, and 10 plastic surgeons.&lt;br&gt;The questionnaire survey at the end of the seminar revealed that the importance of developing a standardized assessment system in Japan was fully recognized. From now on, efforts to develop a standardized assessment system will be continued by the working group in the Japancleft Committee.

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  • Roundtables : Quality assurance in general education : Development and integration of direct and indirect assessment

    松下 佳代, 小野 和宏, 斎藤 有吾

    大学教育学会誌 = Journal of the Liberal and General Education Society of Japan   36 ( 2 )   17 - 21   2014.11

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  • Prospects for Direct Assessment of Problem Solving Competence : Development of Modified Triple Jump in Problem-Based Learning

    小野 和宏, 松下 佳代, 斎藤 有吾

    大学教育学会誌 = Journal of the Liberal and General Education Society of Japan   36 ( 1 )   123 - 132   2014.5

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  • Autotransplantation or replantation of cryopreserved teeth: a case series and literature review Reviewed

    Michiko Yoshizawa, Takahiro Koyama, Naoya Izumi, Kanae Niimi, Yukiko Ono, Hisao Ajima, Akinori Funayama, Toshihiko Mikami, Tadaharu Kobayashi, Kazuhiro Ono, Ritsuo Takagi, Chikara Saito

    DENTAL TRAUMATOLOGY   30 ( 1 )   71 - 75   2014.2

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    Background: The aim of this report was to evaluate the outcome of autotransplantation or replantation of cryopreserved teeth clinically and radiographically. Donor teeth were slowly frozen in a controlled-rate freezer using 5% dimethylsulfoxide (DMSO) and 6% hydroxyethyl starch (HES) as protectants. Seven cryopreserved teeth, with duration of storage ranging from 4 to 36 months, were autotransplanted or replanted at Niigata University Medical and Dental Hospital. Endodontic treatment involving root canal debridement followed by interim root canal filling with calcium hydroxide was started 3 weeks after the operation and continued with replacement of the calcium hydroxide filling at 2-week to 3-month intervals. Three transplants showed periodontal regeneration clinically and radiographically, whereas replacement root resorption was observed in the remaining transplants. From the results, it can be concluded that cryopreserved tooth autotransplantation has potential for clinical use; however, the risk of replacement root resorption remains.

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  • The 5-Year-Olds' Index Seminar:A report from the Japancleft Committee of the Japanese Cleft Palate Association

    SAITO Isao, FUJIWARA1 Yuri, SUSAMI Takafumi, ASAHITO Toshikazu, MAKI Koutaro, YOSHIMURA Yoko, SUZUKI Shigehiko, GOTO Masaaki, ONO Kazuhiro, SAKO Michiyo

    J.Jpn.Cleft Palate Assoc.   39 ( 1 )   46 - 50   2014

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    A seminar on 5-Year Olds&#039; Index hosted by the Japancleft Committee, Japanese Cleft Palate Association took place at the Sanjo Conference Hall, the University of Tokyo on July18-19, 2012. The purpose of the seminar was to provide the opportunity to have an exercise in assessing dental arch relation in patients aged 5 years with unilateral cleft lip and palate. Dr. Nikki Atack and Prof. Jonathan Sandy who had developed the index were invited from the University of Bristol as the lecturers at the seminar. The number of participants was over 80 from various special fields such as plastic surgery, oral surgery, pediatric dentistry and orthodontics. A total of 355 dental models were collected from participating institutions and were employed for evaluation training. As a result of intra-examiner agreement and agreement with Gold standard, almost all delegates obtained an agreement score of 0.80 or above, which would be very suitable and able to assess 5 year olds&#039; models. Although the models collected were not selected based upon critical inclusion criteria, the result of assessment of the Japanese models was very analogous to that of UK Pre-CSAG (Clinical Standard Advisory Group). We hope that the present seminar would be helpful for the improvement of treatment outcomes in patients with cleft lip and palate.

    DOI: 10.11224/cleftpalate.39.46

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  • Introduction of performance assessment into the "Study Skills" course and its practical problems

    Ono Kazuhiro, Nishiyama Hideyoshi, Yagi Minoru, Stegaroiu Roxana, Shigetani Yoshimi, Yamamura Kensuke, Inoue Makoto, Maeda Takeyasu

    新潟大学高等教育研究   1 ( 2 )   5 - 8   2014

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    新潟大学歯学部では,初年次教育として大学学習法を実施している.この授業は講義・演習での知識や技能をもとに,レポート作成とプレゼンテーションを行うもので,その学習活動を通して,間題解決能力,論理的思考力,表現力の開発をねらいとしている.今回,学習成果の直接評価に向けて,パフォーマンス評価を導入すべく,レポートからこれら能力を読み解くルーブリックづくりに取り組んだ.また,この経験からみえてきたパフォーマンス評価の難点とその対処について検討した.その結果,パフォーマンス評価により能力を把握できる可能性が示されたが,導入には教員の理解と協力,能力と関連した適切な評価観点の設定,評価の信頼性を高める工夫,評価と指導の一体化を考慮した授業デザインなど,いくつかの課題があることも明らかになった.The curriculum of Niigata University Faculty of Dentistry provides the &quot;Study Skills&quot; course as first year education. The ultimate goal of this course is to develop student abilities of problem solving, logical thinking and expression. For that purpose, each student is guided through the process of writing a report and presenting its content. To access the degree to which these abilities were achieved, we created a rubric and used it to evaluate the student reports. Based on the experience of this trial, we discussed problems for the introduction of performance assessment into the course. Although performance assessment has a high potential to grasp these abilities, there are some practical problems that may interfere with its introduction, such as &quot;how to involve the faculty in assessment&quot;, &quot;how to establish dimensions of the rubric that appropriately relate with the student abilities&quot;, &quot;how to increase the reliability of assessment&quot;, &quot;how to design the course to allow for a connection between assessment and instruction&quot;.

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  • Three cases of improved eruption direction by surgical rotation of permanent tooth germs

    小山 貴寛, 芳澤 享子, 小野 和宏

    日本口腔外科学会雑誌 = Japanese journal of oral and maxillofacial surgery   59 ( 11 )   704 - 707   2013.11

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    DOI: 10.5794/jjoms.59.704

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  • Development of a Rubric for Writing Assessment and Examination of Its Reliability

    松下 佳代, 小野 和宏, 高橋 雄介

    大学教育学会誌 = Journal of the Liberal and General Education Society of Japan   35 ( 1 )   107 - 115   2013.5

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  • Speech Outcome of Unilateral Cleft Lip and Palate Patients Managed under Two-stage Palatoplasty with Hotz's Plate until 8 Years of Age:&mdash;Evaluation of Furlow's Double-opposing Z-plasty for Soft Palate Repair&mdash;

    TERAO Emiko, TAKAGI Ritsuo, OMINATO Rei, KODAMA Yasumitsu, IIDA Akihiko, IKARASHI Yuki, ONO Kazuhiro

    J.Jpn.Cleft Palate Assoc.   38 ( 1 )   104 - 112   2013.4

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    Forty-two unilateral cleft lip and palate patients who were managed under two-stage palatoplasty with Hotz&#039;s plate and Furlow&#039;s double-opposing Z-plasty (F group) for soft palate repair were evaluated in terms of speech function until 8 years of age. The results were also compared with those of unilateral cleft lip and palate patients who underwent Perko&#039;s Widmaier modification method (P group: 75 patients) for soft palate repair.&lt;br&gt;1. There was no significant difference between the F group and P group on velopharyngeal competence (VPC) at 8 years of age. The VPC of the F group was almost the same as that of one-stage platoplasty patients reported before.&lt;br&gt;2. The VPC of the F group was significantly improved between 4 years and 5 years of age. This was earlier than that of the P group, which improved after hard palate closure.&lt;br&gt;3. Normal articulation in the F group had developed better by 8 years of age than in the P group, because of fewer abnormal articulations and larger number of spontaneous normal development. However, the peak of achieving good VPC was after hard palate closure in both groups, and a majority gained normal articulation after finishing speech training by a speech therapist.&lt;br&gt;4. Recently, we perform the hard palate closure operation at around 4 years of age, in order to avoid the delayed development of speech function.&lt;br&gt;We must continue to evaluate the long-term effects for speech function and jaw growth after earlier hard palate closure.

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  • Spatial and temporal relationship between swallow-related hyoid movement and bolus propulsion during swallowing

    Magara Jin, Hayashi Hirokazu, Kanda Chika, Hori Kazuhiro, Taniguchi Hiroshige, Ono Kazuhiro, Inoue Makoto

    Nihon gaku koukukinou gakkai zasshi   20 ( 1 )   22 - 32   2013

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    The present study was undertaken to validate how descent of the hyoid position, considered as a pathological condition of dysphagia, affect swallowing function by evaluating spatial and temporal hyoid excursion, hyoid position and bolus transmission in healthy volunteers and patients with dysphagia.&lt;br&gt;&amp;nbsp;All subjects, including 65 patients with dysphagia and 10 normal volunteers, were examined using videofluorographic images. These images were analyzed to measure the time series of hyoid movement and bolus transmission based on the moment the tip of the tongue starts to move. The hyoid position was also investigated, and the origin was defined on the anterior ridge of the fourth cervical vertebra. Statistical comparison between both groups was then performed.&lt;br&gt;&amp;nbsp;The oral and pharyngeal transit times were prolonged in the patient group; in addition, entry of the bolus head into the pharynx was significantly earlier than the start of pharyngeal swallowing (start of the rapid hyoid elevation). There was no significant difference in the hyoid position between the two groups when the origin was defined on the anterior ridge of the fourth cervical vertebra. Further evaluation was performed by classifying patients with dysphagia by the diseases causing their dysphagia. A similar hyoid trajectory among the classified groups was observed after the onset of the swallowing reflex; in contrast, the hyoid bone showed complicated movement before the swallowing reflex occurred. The hyoid position may affect the delay in the swallowing onset because positive correlation between the distance and time of hyoid movement was observed before swallowing reflex in some diseases.

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  • Roundtables : Toward Direct Assessment of Learning Outcomes : Effectiveness of Performance Assessment in Higher Education

    松下 佳代, 坂本 尚志, 小野 和宏

    大学教育学会誌   34 ( 2 )   86 - 89   2012.11

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  • Permanent Dentition after Soft Palate Closure by Furlow's Method in Two-stage Palatoplasty

    IKARASHI Yuki, IIDA Akihiko, ONO Kazuhiro, ASAHITO Toshikazu, SAITO Isao, TAKAGI Ritsuo

    J.Jpn.Cleft Palate Assoc.   37 ( 3 )   210 - 219   2012.10

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    The permanent dentition at dental age IIIc described by Hellman, of patients with complete unilateral cleft lip and palate who underwent soft palate closure with Furlow&#039;s method (F-group), introduced with the aim of achieving better results of both speech and maxillary growth in two-stage palatoplasty, was compared to other patients who underwent Perko&#039;s method (P-group) and noncleft subjects (C-group).&lt;br&gt;The results were as follows:&lt;br&gt;1. Regarding the upper dental arch width, the distance between bilateral points of maxillary tuberosity in the F-group was smaller than that in the P- and C-groups. The arch width of the canine to premolar region was the same as that of the P-group, but slightly constricted compared to the C-group.&lt;br&gt;2. The upper alveolar arch length tended to be longer compared to the P-group, and the distance from the cuspid to the maxillary tuberosity line was longer than that of the C-group. There was no difference with the P-group regarding the upper dental arch length, but it was smaller compared to the C-group.&lt;br&gt;3. There was no difference with the C-group regarding the lower dental arch width, and only the width between the first molar of the P-group was larger than that of the F- and C-groups.&lt;br&gt;4. There was no significant difference among the three groups regarding the lower dental arch length.&lt;br&gt;5. While 2 of 17 cases (11.8%) had anterior or posterior cross bite, it was observed in 11 of 29 cases (37.9%) in the P-group.&lt;br&gt;Though there was a slight difference in the permanent dental arch form of the F-group compared to that of the P-group, reflecting the surgical method, there were no significant differences and the form was close to that of the C-group. The occlusal condition was not inferior to the P-group and good maxillary growth was obtained. Together with the improvement of speech results, it was considered that Furlow&#039;s method is useful for two-stage palatoplasty.

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  • Alterations in intermediate filaments expression in disc cells from the rat temporomandibular joint following exposure to continuous compressive force Reviewed

    Jin Magara, Kayoko Nozawa-Inoue, Akiko Suzuki, Yoshiro Kawano, Kazuhiro Ono, Shuichi Nomura, Takeyasu Maeda

    JOURNAL OF ANATOMY   220 ( 6 )   612 - 621   2012.6

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    The articular disc in the temporomandibular joint (TMJ) that serves in load relief and stabilizing in jaw movements is a dense collagenous tissue consisting of extracellular matrices and disc cells. The various morphological configurations of the disc cells have given us diverse names, such as fibroblasts, chondrocyte-like cells and fibrochondrocytes; however, the characteristics of these cells have remained to be elucidated in detail. The disc cells have been reported to exhibit heterogeneous immunoreaction patterns for intermediate filaments including glial fibrillary acidic protein (GFAP), nestin and vimentin in the adult rat TMJ. Because these intermediate filaments accumulate in the disc cells as tooth eruption proceeds during postnatal development, it might be surmised that the expression of these intermediate filaments in the disc cells closely relates to mechanical stress. The present study was therefore undertaken to examine the effect of a continuous compressive force on the immunoexpression of these intermediate filaments and an additional intermediate filament muscle-specific desmin in the disc cells of the TMJ disc using a rat experimental model. The rats wore an appliance that exerts a continuous compressive load on the TMJ. The experimental period with the appliance was 5 days as determined by previous studies, after which some experimental animals were allowed to survive another 5 days after removal of the appliance. Histological observations demonstrated that the compressive force provoked a remarkable acellular region and a decrease in the thickness of the condylar cartilage of the mandible, and a sparse collagen fiber distribution in the articular disc. The articular disc showed a significant increase in the number of desmin-positive cells as compared with the controls. In contrast, immunopositive cells for GFAP, nestin and vimentin remained unchanged in number as well as intensity. At 5 days after removal of the appliance, both the disc and cartilage exhibited immunohistological and histological features in a recovery process. These findings indicate that the mature articular cells are capable of producing desmin instead of the other intermediate filaments against mechanical stress. The desmin-positive disc cells lacked a-smooth muscle actin (a-SMA) in this study, even though desmin usually co-exists with a-SMA in the vascular smooth muscle cells or pericytes. Because the precursor of a pericyte has such an immunoexpression pattern during angiogenesis, there is a further possibility that the formation of new vessels commenced in response to the extraordinary compressive force.

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  • 二段階口蓋形成手術法におけるFurlow法の応用 口蓋形成術の歴史的背景と15年200例の経験から

    高木 律男, 小山 貴寛, 児玉 泰光, 小野 和宏, 飯田 明彦

    小児口腔外科   22 ( 1 )   14 - 29   2012.6

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    口蓋形成手術の歴史的背景について述べ、1986年にFurlowが報告したdouble opposing Z-plastyと称される新しい口蓋形成術(Furlow法)の手技と問題点、言語発達や顎発育の効果などについて概説した。Furlow法は、軟口蓋部に起因する鼻咽腔閉鎖機能不全が適応となる。問題点としては瘻孔発生、術後の閉塞性睡眠時無呼吸症候群、中耳への影響が挙げられる。Furlow法は、二段階口蓋形成手術法における軟口蓋単独の手術方法として最も適した方法である。

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  • A Clinical Analysis on Cleft Lip and/or Palate Patients in the Orthodontic Clinic, Niigata University Medical and Dental Hospital in the past 30 years (1979-2008)

    TAKEYAMA Masaki, ASAHITO Toshikazu, KANAYAMA Kiyoshi, OISHI Megumi, KOHARA Akihiro, ONO Kazuhiro, SAITO Chikara, TAKAGI Ritsuo, SAITO Isao

    J.Jpn.Cleft Palate Assoc.   36 ( 3 )   183 - 190   2011.10

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    A clinical and statistical analysis was carried out on patients with cleft lip and/or palate at the Orthodontic Clinic, Niigata University Medical and Dental Hospital in the past 30 years (1979&amp;sim;2008). The results obtained were as follows:&lt;br&gt;1. The patients consisted of 602 males (52.9%) and 537 females (47.1%).&lt;br&gt;2. Cleft morphology was classified as the following.&lt;br&gt;Cleft lip and palate (CLP): 51.5%, cleft palate (CP): 23.8%, cleft lip and alveolus (CLA): 19.1%, cleft lip (CL): 5.4% and others: 0.2%. As for the ratio of the cleft side, the left side in unilateral CLP, CLA and CL was higher than the right side. Male patients were more in CLP, CLA and CL than females, while female patients were more in CP.&lt;br&gt;3. The number of new outpatients was changing year by year in the past 30 years but no specific tendency was found.&lt;br&gt;4. The peak age of the first visit was 4 years and the majority of patients visited for their first time at the age of 4-6.&lt;br&gt;5. The majority of patients were referred from other dental departments in our hospital, and 92.5% of the patients were referred from the department of Oral and Maxillofacial Surgery.&lt;br&gt;6. The large majority of patients investigated lived in Niigata prefecture.&lt;br&gt;7. Most of the cleft lip and/or palate patients born between 1979 and 2001 in Niigata prefecture consulted our department.

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  • Phenotypes of articular disc cells in the rat temporomandibular joint as demonstrated by immunohistochemistry for nestin and GFAP Reviewed

    Hitoshi Miyako, Akiko Suzuki, Kayoko Nozawa-Inoue, Jin Magara, Yoshiro Kawano, Kazuhiro Ono, Takeyasu Maeda

    JOURNAL OF ANATOMY   219 ( 4 )   472 - 480   2011.10

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    The articular disc is a dense collagenous tissue containing disc cells that are phenotypically described as chondrocyte-like cells or fibrochondrocytes. Despite the possible existence of these phenotypes in systemic joints, little is known about the detailed classification of the articular disc cells in the temporomandibular joint. In this immunocytochemical study we examined the localization and distribution patterns of nestin and glial fibrillary acidic protein (GFAP) in the articular disc of the rat temporomandibular joint at postnatal day 1, and weeks 1, 2, 4 and 8, based on the status of tooth eruption and occlusion. Nestin and GFAP are intermediate filament proteins whose expression patterns are closely related to cell differentiation and cell migration. Both types of immunopositive cell greatly increased postnatally to a stable level after postnatal week 4, but they showed different distribution patterns and cell morphologies. Nestin-reactive disc cells, which were characterized by a meagre cytoplasm and thin cytoplasmic processes, were scattered in the articular disc, whereas GFAP-positive cells, characterized by broader processes, existed exclusively in the deeper area. In mature discs, the major proportion of articular disc cells exhibited GFAP immunoreactivity. Furthermore, a double-immunostaining demonstrated that the nestin-negative cells, consisting of GFAP-positive and -negative cells, exhibited immunoreactions for heat shock protein 25. These findings indicate that the articular disc cells comprise at least three types in the rat temporomandibular joint and suggest that their expressions closely relate to mechanical loading forces within the joint, including occlusal force, as observed through postnatal development.

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  • Outcome and Further Development of the "Study Skills" Course as First-year Education

    ONO Kazuhiro, YAGI Minoru, STEGAROIU Roxana, OHSHIMA Hayato, NISHIYAMA Hideyoshi, YAMAKI Masaki, MAEDA Takeyasu

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   27 ( 2 )   69 - 77   2011.8

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  • Analysis of Current State of Dental Hygiene Clinical Training in the Department of Oral Health and Welfare, Niigata University Faculty of Dentistry

    ISHIKAWA Yuko, FUKUSHIMA Masayoshi, YAGI Minoru, SHIBATA Satoko, OHUCHI Akitsugu, YAMAZAKI Kazuhisa, KUROKAWA Kouichi, STEGAROIU Roxana, ONO Kazuhiro

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   27 ( 2 )   78 - 85   2011.8

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    歯科衛生士教育のなかでの臨床実習は、それまで学んだ知識と技術を統合する意味で重要である。本研究では、新潟大学歯学部口腔生命福祉学科における4年次の臨床実習について現状を明らかにするために、本学科の診療室である「お口の健康室」の予約表と日計表、および1〜3期生の学生自身が記録した「臨床実習の手引」のケース集計表に基づいて、臨床実習の現状を評価した。また、「臨床実習の手引」の記載方法の検討を行うために、一部の臨床実習のケース項目に対して、学生からの「申告値」と教員が算定した「算定値」との一致の程度について分析した。さらに、3期生に対して「臨床実習の手引」への記載方法などに関する記述式アンケートを行った。その結果、実習ケース数および「お口の健康室」で学生が担当した患者数は、1年目と比較して2年目で増加していた。また、学科で指定している経験期待症例数に学生全員が達したケース項目の割合は減少する傾向にあった。記載方法については、「申告値」と「算定値」の一致の程度が低いケース項目が一部あり、アンケート結果からも、それらのケース項目はケース内容の解釈が不明確であることが示唆された。今後、4年制歯科衛生士教育の特色を出すケース項目を追加し、実習評価法と併せて実習修了判定方法を再検討する必要があると考えられた。(著者抄録)

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  • 新潟大学における初年次教育の役割と課題 Reviewed

    小野和宏, 八木 稔, ステガロユ ロクサーナ, 大島勇人, 西山秀昌, 八巻正樹, 前田健康

    日本歯科医学教育学会雑誌   27 ( 2 )   17 - 25   2011.8

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  • Establishment of a Student-centered Problem-based Learning Curriculum : Seven Years of Experience at the Department of Oral Health and Welfare, Niigata University Faculty of Dentistry

    Ono Kazuhiro, Ohuchi Akitsugu, Maeda Takeyasu

    新潟歯学会雑誌   41 ( 1 )   1 - 12   2011.6

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    新潟大学歯学部口腔生命福祉学科では「食べること」から保健・医療・福祉の統合を目指しており、その教育に2004年よりProblem-based Learning(PBL)テュートリアルを導入している。PBLテュートリアルとカリキュラムの概要を紹介すると共に、カリキュラムに対する学習者の認識、学習成果に関する卒業生の自己評価、卒業時に受験資格を得る歯科衛生士と社会福祉士の国家試験合格率、進学・就職状況について述べた。

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  • Clinical study on root resorption of autotransplanted teeth with complete root formation

    Kanae Niimi, Michiko Yoshizawa, Toshiko Sugai, Tadaharu Kobayashi, Kazuhiro Ono, Ritsuo Takagi, Takashi Okiji, Chikara Saito

    Asian Journal of Oral and Maxillofacial Surgery   23 ( 1 )   18 - 24   2011.3

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    Introduction: The main reasons for the unsuccessful autotransplantation of teeth are the failure of initial healing and root resorption. The aim of this study was to elucidate the relationship between donor teeth factors and the prognosis of the transplants in which root resorption occurred. Materials and methods: The study evaluated 110 patients with 117 transplants. The successful group included the cases which healed well, with only minor problems. The unsuccessful group included the cases with transplant-loss and progressive problems. The unsuccessful group and minor-trouble cases were judged with the type of problems; i.e. failure of initial healing, root resorption, and others. Root resorption was classified into 3 types; inflammation resorption, replacement resorption and cervical root resorption. The prognostic factors were evaluated to analyze the difference between rapidly progressing root resorption and the stable resorption. Results: There were 20 unsuccessful transplants. In the unsuccessful group, rapidly progressing replacement root resorption was observed in 11 transplants. In the successful group, minor problems such as stable root resorption were found in 16 transplants. At least one of the atypical root shapes (divergent, curve, and hypertrophy), probing pocket depth of more than 4. mm, and/or extrusion were significantly more frequent in the replacement root resorption cases compared to cases with no significant findings. Probing pocket depth of more than 4. mm and/or extrusion, dental caries, history of restoration, root canal treatment were significantly more frequent in rapidly progressing replacement root resorption cases compared to stable root resorption cases. Conclusions: Abnormal root shape, deep periodontal pocket, dental caries, restoration and root canal treatment of donor teeth are factors associated with progressive replacement root resorption after the autotransplantation of teeth. © 2010 Asian Association of Oral and Maxillofacial Surgeons.

    DOI: 10.1016/j.ajoms.2010.10.005

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  • A Summary of the Faculty Development (FD) in the Niigata University Faculty of Dentistry and Future Prospects

    AJIMA Hisao, UOSHIMA Katsumi, ONO Kazuhiro, FUJII Noritaka, INOUE Makoto, YAMAMURA Kensuke, SAITOU Isao, OKIJI Takashi, TAKAGI Ritsuo, MAEDA Takeyasu

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   26 ( 3 )   349 - 353   2010.12

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    新潟大学歯学部では、教員の資質向上を目的として、平成14年にFD委員会を発足させた。今回、これまで行ってきたFaculty development(FD)活動の概要を報告するとともに、歯学部FDと大学院FDとの連携やスムースな移行を検討するための体系化マップを作成し、FDのあり方や方向性について検討した。これまでに行われてきたFD活動を列挙して体系化マップを作成し、これまでの問題点や改善点を検証して今後に必要なプログラムの立案を行った。委員会発足当初は、全教員を対象として学生教育に必須と考えられる基本的な知識・技能・態度の習得に力点をおいたFD活動が行われていた。しかし近年では、新任者から段階的に研修活動ができるようにFDプログラムの整備がなされ、計画的にFDを開催するとともに、個別対応型FDや参加・体験型FDへとその活動の中心が推移している。これまでの本委員会の活動を体系化マップとしてまとめることにより、平成19年度からは、その役割が、大学院教育の実質化促進へと展開しつつあることが明確になり、今後は歯学部FDで積み重ねた経験を基に、高いレベルの大学院FDに移行させるためのプログラム立案が可能と考えられた。今後は単なるイベント型FDのみならず、各教員の日常的な研修環境の整備やニーズに即したプログラムの企画を通して、教員の研究指導力の開発を目標とすることが重要であると思われた。(著者抄録)

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  • 口唇口蓋裂一次症例の一貫治療(この10年の新展開) 二段階法対一段階法 この10年で結論は出たのか

    小野 和宏

    日本口腔外科学会雑誌   56 ( 11 )   628 - 635   2010.11

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    唇顎口蓋裂治療において、出生時から成人までの一貫治療が重要といわれている。新潟大学医歯学総合病院口腔外科で1983年から採用している二段階口蓋形成手術法の治療成績と単一施設研究の限界について述べた。また、新潟大学、東北大学、昭和大学、東京大学、愛知学院大学、大阪大学の6施設が実施した唇顎口蓋裂治療に関する多施設比較研究(Japancleftプロジェクト)の結果の一部を紹介し、問題点について述べた。

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  • Intraoral Grafting of Ex Vivo Produced Oral Mucosa Equivalents (EVPOME) Applied to Patients with Cleft Lip and Palate

    IIDA Akihiko, YOSHIZAWA Michiko, KOYAMA Takahiro, SAITO Taro, TAKAGI Ritsuo, SAITO Chikara, SAITO Isao, ONO Kazuhiro, IZUMI Kenji

    J.Jpn.Cleft Palate Assoc.   35 ( 3 )   235 - 240   2010.10

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    This report presents the use of &lt;I&gt;ex vivo&lt;/I&gt; produced oral mucosa equivalent (EVPOME) applied to an oral mucosa defect in two patients with cleft lip and palate. Autologous keratinocytes were placed and propagated in a chemically-defined, animal product and a xenogeneic feeder layer free culture system. Cells were then seeded and cultured on an acellular dermal substrate, AlloDerm&lt;sup&gt;&amp;reg;&lt;/sup&gt;, which provides strength, durability, and elasticity to the graft.&lt;br&gt;In case 1, a 20-year-old female underwent closure of the oronasal fistula in the midline of the hard palate using a rotational palatal flap. A circular EVPOME graft (approximately 20 mm in diameter) was grafted onto the bone surface of the donor site of the flap. In case 2, a 16-year-old male underwent vestibuloplasty in the premaxilla region. After trimming, two circular EVPOME grafts were placed over the intact periosteum.&lt;br&gt;The grafts were easily fixed in place to the surrounding scarred mucosa. Although the underlying tissue of the EVPOME graft sutures was scarred, graft adherence was achieved within a week. The successful clinical outcome reported here suggests the efficacy of EVPOME grafts onto a less-vascularized, scarred tissue, and that the use of EVPOME grafts is highly applicable for patients with cleft lip and palate. EVPOME grafting could be extended especially toward pediatric patients with cleft lip and palate for reconstruction of oral mucosa defects by using cryopreserved autologous keratinocytes and by developing a novel material to ensure a steady supply of scaffold instead of the man-made AlloDerm&lt;sup&gt;&amp;reg;&lt;/sup&gt;.

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  • Spontaneous Narrowing of the Residual Hard Palate Cleft after Furlow's Palatoplasty in Two-Stage Palatoplasty : Determination of Optimal Timing of Hard Palate Closure

    IIDA Akihiko, TAKAGI Ritsuo, ONO Kazuhiro, TERAO Emiko, KOYAMA Takahiro, KOBAYASHI Takanori, IKARASHI Yuki

    J.Jpn.Cleft Palate Assoc.   35 ( 3 )   195 - 206   2010.10

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    Objectives; The aim of this study was to determine the optimal timing of hard palate closure with low surgical damage and to assess the difficulty in achieving early acquisition of normal articulation using Furlow&#039;s palatoplasty (F-group), which provides earlier velopharyngeal competence than by Perko&#039;s method (P-group).&lt;br&gt;Subjects and Methods;&lt;br&gt;1. Serial study cast models of the F-group (unilateral cleft lip and palate, N=47) were used to evaluate the reduction in the residual cleft size in the hard palate.&lt;br&gt;2. The surgical results of the F-group, such as the maximum cleft width, operation time, blood loss and fistula rate were compared with those of the P-group.&lt;br&gt;3. The surgical damage and difficulty of hard palate closure in the F-group was also subjectively evaluated by inspecting randomly-selected cast models at four years of age and at the time of hard palate closure.&lt;br&gt;Results;&lt;br&gt;1. The anterior cleft width showed a significant reduction by two years of age.&lt;br&gt;2. The posterior cleft width also showed a significant reduction by three years of age. On the other hand, the posterior alveolar width showed a significant increase by four years of age.&lt;br&gt;3. The maximum cleft width and the blood loss in the F-group and P-group were 4.06 mm and 15.3 g, and 6.02 mm and 34.6 g, respectively (p &lt; 0.001). There was no difference in the operation time or the fistula rate.&lt;br&gt;4. The subjective evaluation of the surgical damage and difficulty in achieving hard palate closure in the F-group was low. The agreement between the evaluations at four years of age and at the time of hard palate closure was high.&lt;br&gt;Conclusion; This study showed that the hard palate could be closed at 4 years of age with low surgical damage and little difficulty by applying Furlow&#039;s method.

    DOI: 10.11224/cleftpalate.35.195

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  • Surgical Rotation of Tooth Germ of Lateral Incisor Adjacent to Alveolar Cleft Along with Bone Graft : A Case Report

    IIDA Akihiko, TAKAGI Ritsuo, ONO Kazuhiro, YAMAKI Masaki, SAITO Isao, INAMI Yoshihiro

    J.Jpn.Cleft Palate Assoc.   35 ( 3 )   241 - 246   2010.10

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    We reported a case of bilateral cleft lip and palate treated by surgical rotation of tooth germ of the lateral incisor adjacent to the alveolar cleft along with bone graft. The patient was a 7-year, 4-month-old boy at the time of the operation. The alveolar cleft existed only on the right side. The image findings revealed that the upper right lateral incisor was conical, infraversed and inclined mesialy at about 90 degrees. The degree of completion of root formation described by Moorrees was Ri to R&lt;SUB&gt;1/4&lt;/SUB&gt;. The right upper second premolar was also absent. During the operation, the tooth germ of the lateral incisor was exposed on the cleft margin of the minor segment. After extraction of the upper right deciduous canine and removal of the dental sac of the crown of the lateral incisor, the lateral incisor was inclined toward the socket of the deciduous canine in order not to move the location of the root apex. Finally, particulate cancellous bone and marrow from the iliac crest were grafted and the wound was completely closed. The lateral incisor erupted at 8 months and the root formation was completed by 2 years after the operation. There has been no evidence of root resorption, curved root or pulpa canal obliteration in the 7 years since the operation.&lt;br&gt;In order to achieve successful results of surgical rotation of tooth germ, it is important to operate at the initial root formation stage, with less surgical damage, and not to move the location of the root apex. It is also recommended that the degree of root rotation should not exceed 90 degrees. If these conditions are satisfied, the surgical repositioning of the tooth becomes a treatment option for occlusal formation of the alveolar cleft region where misdirection and dislocation of teeth occur frequently.

    DOI: 10.11224/cleftpalate.35.241

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  • The effects of timing of secondary alveolar bone graft on craniofacial morphology in patients with unilateral cleft lip and alveolus.

    Hemoudi Yassin, Yamada Kazuhiro, Asahito Toshikazu, Ono Kazuhiro, Saito Chikara, Takagi Ritsuo, Saito Isao

    新潟歯学会雑誌   40 ( 1 )   19 - 28   2010.6

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    Objective: The purpose of this study was to compare the effect of early and late bone grafts in patients with Cleftlip and alveolus only, consequently excluding the influence of palatal closure on craniofacial growth. Subjects and Methods: The subjects were chosen from the records of the Orthodontic Clinic, Niigata University Medical and Dental Hospital. 30 patients with unilateral cleft lip and alveolus only (without cleft palate) were chosen and divided into 2 groups based on the following selection criteria: Early bone grafting (EBG) at a mean age of 8 years and 3 months. Late bone grafting (LBG) at a mean age of 13 years and 7 months. The majority had orthodontic treatment during the mixed dentition. Lateral cephalograms were traced, and then 22 angular and 27linear measurements were analyzed. Results: Mann-Whitney test showed that all angular measurements were not significantly different between the 8and the 14 years old subjects in the EBG and LBG groups. The difference in the value of A&#039;-PNS between 14 and 8 years showed a significant difference when the groups were compared. Conclusion: The present study showed decrease in anteroposterior maxillary growth in the EBG group. Apossible reason for our finding might be the inhibition of maxillary growth that caused bone grafting operation and the short evaluation period (around 1 year) in the LBG group, while it was longer for the EBG group. Grafted bone is possibly allowed to undergo resorption during remodeling or displacement of the new bone with longer time. As a result, the decrease in the maxillary anteroposterior length exhibited by the distance from A&#039;- PNS was recognized in the EBG group.目的:本研究の目的は片側性唇顎裂患者において二次的顎裂部骨移植の時期の違いが顎顔面形態に及ぼす影響を明らかにすることである。対象:新潟大学医歯学病院矯正歯科診療室において管理されている片側性唇顎裂患者のうち,早期二次的顎裂部骨移植を施行した17 名(骨移植施行平均年齢8歳3か月,以下早期群と略す),晩期二次的骨移植群骨移植を施行した13 名(平均年齢13 歳7か月,以下晩期群と略す)の計30 名を対象とした。これらの8歳時ならびに14 歳時の側面頭部X 線規格写真をトレースし,22 項目の角度計測ならびに27 項目の距離計測を行ない,両群の8歳時ならびに14 歳時の値,および8歳時から14 歳時の変化について両群間で比較した。結果:8歳時ならびに14 歳時両時期において,角度計測項目ならびに距離計測項目のすべての計測項目について両群間で有意差は認められなかった。しかしながら,8歳から14 歳の変化量に関し距離計測項目のうちA&#039;-PNS において,両群間で有意差を認めた。結論:本研究では上顎骨の前後的な長さに関してその変化量に差を認めた。その理由として1.骨移植術施行時の外科的侵襲による成長抑制,2.晩期群では骨移植後移植骨の置換が完了せず,移植骨の吸収も少ない反面,早期群では骨移植後5年前後経過しており移植骨の置換がおこなわれ,A 点付近の骨吸収が生じること,から,上顎骨の前後的な長さに差が生じたと考えられた。

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  • Evaluation of the New Dental Curriculum for Undergraduates at the Niigata University Faculty of Dentistry

    ONO Kazuhiro, YAGI Minoru, OHUCHI Akitsugu, UOSHIMA Katsumi, FUJII Noritaka, HAYASHI Takafumi, SAITO Isao, OKIJI Takashi, MAEDA Takeyasu

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   26 ( 1 )   49 - 57   2010.4

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    新潟大学歯学部歯学科では、21世紀の社会動向を見通し、2000年度より新教育課程を開始した。新課程は、認知、精神運動、情意の3領域の教育を密接に連関させることにより学生の知的好奇心を喚起させ、教育目標とする人材育成を効果的に達成しようとするもので、その方策として問題発見解決型学習を展開している。今回、カリキュラム評価を目的に、2001・2002年度入学、6年一貫教育、新潟大学医歯学総合病院における卒業後1年間の歯科医師臨床研修の3条件を満たす卒業生を対象として、新課程で獲得が期待される学習成果、すなわち、知識・理解、専門的能力、汎用的能力、態度・姿勢の4つの観点からなる25項目の達成度に関して、4段階の基準で自己評価を依頼した。また、臨床研修で1年間にわたり卒業生を観察してきた指導歯科医師にも、同じ項目について対象者の達成度を評価するよう依頼した。卒業生と指導歯科医師それぞれが学習成果の達成度を評価し、その結果にさほど矛盾がなければ、一致した評価結果は信頼できると仮定し、両者の一致度を指標として新課程の教育効果を検討した。その結果、卒業生は科学的根拠に基づいた歯科医療を実践する力、問題を発見し解決する力、コミュニケーションする力、適切に判断し行動する力、さまざまな価値観を受容する力の育成がなされており、新課程は一定の教育効果をもち、その狙いはおおむね達成されていると考えられた。(著者抄録)

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  • Clinical Study on Prognostic Factors of Autotransplantation of Teeth with Complete Root Formation. Reviewed

    Sugai T, Yoshizawa M, Kobayashi T, Ono K, Takagi R, Kitamura N, Okiji T, Saito C

    Int J Oral Maxillofac Surgery   39 ( 12 )   1193 - 1203   2010

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    Autotransplantation is often performed to replace a missing tooth, but tooth autotransplantation has been reported in fewer teeth with complete root formation than those with incomplete root formation. The aim of this prospective study was to evaluate the factors that affect the prognosis of autotransplantation of teeth with complete root formation. 109 patients with 117 transplants were studied. Of the 117 transplants investigated, 14 (12%) failed during the observation period. The overall 1-year survival rate was 96%; the 5-year survival rate was 84%. The major causes of failure were unsuccessful initial healing and replacement root resorption with periodontal inflammation. Factors significantly associated with unsuccessful transplantation, in single factor analysis, were age 40 years or more, molar tooth as donor, probing pocket depth to 4 mm or more, history of root canal treatment, multi-rooted teeth and fixation with sutures. Pocket depth of 4 mm or more and history of root canal treatment appeared to increase the risk of unsuccessful transplantation in multivariate analysis. It is suggested that the pocket depth of the donor tooth and history of root canal treatment are related to the healing of paratransplantal tissue and root resorption. © 2010 International Association of Oral and Maxillofacial Surgeons.

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  • A case of immediate tooth transplantation after residual cyst extirpation.

    Ajima Hisao, Yoshizawa Michiko, Ono Kazuhiro, Izumi Naoya, Niimi Kanae, Koyama Takahiro, Sugai Toshiko, Okiji Takashi, Saito Chikara, Takagi Ritsuo

    新潟歯学会雑誌   39 ( 2 )   153 - 158   2009.12

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    今回我々は,受容部に認めた残留嚢胞の摘出と同時に軽度の歯周炎を有する歯を移植し,良好に経過した症例を経験したので報告するとともに,その成功要因について移植歯と受容部の予後因子について検討した。症例は53歳,女性。移植歯は上顎左側智歯で,歯周ポケット4mm,付着の喪失4mm で軽度の歯周炎を呈していた。受容部は下顎右側第一大臼歯相当部歯槽堤で,パノラマおよびデンタルX線写真で歯槽頂のやや下方に境界明瞭で類円形のX線透過像が認められた。移植歯は3根でやや肥大していたが,歯根膜の付着量は口蓋根で11mm,頬側根で8mmであった。嚢胞の摘出に際しては,同部が移植窩となることを考慮して病変にアプローチしたところ,歯槽頂より7~8mm下方に嚢胞を認め摘出した。そのため移植窩はその下方で嚢胞摘出腔と連続したが,歯槽頂から7~8mmの高さでは4壁の歯槽骨が確保でき,移植歯と移植窩の適合は良好であった。術後3週目で固定を除去し,根管治療を開始した。術後3か月目に根管充填を行い,移植後8か月で最終補綴治療を行ったところ,デンタルX線写真でも移植歯周囲の骨新生は良好であった。現在,術後6年を経過しているが経過は良好である。この理由として,移植窩形成時に移植窩上縁に4壁の歯槽骨が確保でき,移植歯の歯頸部付近での適合が良好であったこと,移植歯の歯根膜付着が確保できたことなどが考えられた。The purposes of this article were to report a successful case of immediate autotransplantation after surgical extirpation of a residual cyst, and to review donor tooth- and recipient site-associated factors that favored the outcome. The case is of a 53 years old female. The donor tooth was the maxillary left third molar that developed mild periodontitis with probing pocket depth of 4 mm and attachment loss of 4 mm. In panoramic and dental x-rays, the lesion appeared at the alveolar crest slightly downward in the mandibular right first molar region as a well-demarcated unilocular radiolucency. The donor tooth had three slightly hypertrophic roots, but with enough attached periodontium on root surfaces. As a result of surgical extirpation of the cyst observed at 7-8mm depth below the alveolar ridge, the bottom of the transplant socket became continuous with the extirpation defect. However, we were able to preserve the buccal and lingual walls of the alveolar bone, and successfully prepared a 7-8-mm-deep, 4-wall transplant socket that conformed well to the transplanted tooth. We removed the resin-wire splint used for fixation 3 weeks postoperatively and started endodontic treatment. We performed root canal filling with gutta-percha 3 months postoperatively and prosthetic treatment was done 8 months postoperatively. Control radiographs taken during 6 years of follow-up displayed disappearance of radiolucency, clearly visible periodontal ligament space around the transplant, and no signs of root resorption, indicating good healing. The favorable outcome of this case may be attributable to the following factors: (i) successful creation of a four-wall transplant socket; (ii) good initial stability due to good conformity of the cervix of the transplant; (iii) absence of osteosclerotic findings around the cystic radiolucency at the first molar region; and (iv) successful periodontal reattachment of the donor tooth.

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  • An Evaluation of the New Dental Curriculum for Undergraduates at the Niigata University Faculty of Dentistry

    Ono Kazuhiro, Yagi Minoru, Ohuchi Akitsugu, Uoshima Katsumi, Hayashi Takafumi, Saito Isao, Okiji Takashi, Maeda Takeyasu, Yamada Yoshiaki

    新潟歯学会雑誌   39 ( 1 )   29 - 40   2009.6

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    新潟大学歯学部歯学科では,2000年度より新教育課程を開始した。新課程は,認知,精神運動,情意3領域の教育を密接に連関させることにより学生の知的好奇心を喚起させ,教育目標とする人材育成を効果的に達成しようとするもので,その方策として問題発見解決型学習を展開している。今回,この課程で学んだ2006年度卒業生を対象としてカリキュラム評価を実施した。卒業後1年が経過した臨床研修修了時に記名式調査用紙を郵送し,カリキュラム・授業に対する満足度について質問した。また,カリキュラムの教育効果に関して,教育目標とする人材への到達度および学習成果の達成度について自己評価を依頼した。なお,新潟大学医歯学総合病院において臨床研修を受けた卒業生に対して,指導歯科医師による教員評価を行い,卒業生の自己評価の信頼性についても検討した。対象者40名中24名,60.0%から調査用紙の返送があり,以下の結果を得た。1.カリキュラムに対する学習者の満足度は良好であった。2.全般に教育目標への到達度は良好で,卒業生は人間性豊かな人材,問題発見解決型人材へ成長していた。3.卒業生は科学的根拠に基づいた歯科医療を実践する力,問題を発見し解決する力,意思決定し自己責任を負う態度の育成がなされていた。以上から,新課程は一定の教育効果をもち,その目的はある程度,達成されていると考えられた。We have run a new dental curriculum at the Niigata University Faculty of Dentistry since April 2000.The aim of this new curriculum was to create mature dentists effectively through the activation of knowledge curiosity by correlation of three domains, cognitive, psychomotor and affective. We have adopted problem discovering/solving type learning for this purpose. In this investigation, we evaluated this curriculum. Subjects comprised graduates who had studied based upon this new curriculum all the way through for the first time, and graduated in March 2006. We carried out the survey by sending several questionnaires to them one year after graduation when they finished their residency program. We asked them regarding their appreciation of the new curriculum and programs along with their self-assessment of their personal maturation as dentists and learning effects. Reliability of the self-assessments was also investigated in comparison with the evaluation by the instructors during the residency program at the Niigata University Hospital. The survey was collected from 24 graduates out of 40 (60.0%). The results were as follows: 1. Satisfaction rate of the curriculum was good. 2. Accomplishment of designated aims was generally well and their personal maturation along with their problem discovering / solving abilities was achieved. 3. The graduates developed their ability of evidence based dentistry, problem discovering / solving and responsibility for their decisions. Taking the above results into consideration, we concluded that our new curriculum is effective to some extent and the revision has been successful.

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  • A case of descending necrotizing mediastinitis arising from odontogenic infection with NSAID-induced gastric ulcer in a very elderly patient

    KODAMA Yasumitsu, ONO Kazuhiro, ARASHIYAMA Takanori, OSEKI Koushi, TSUCHIDA Masanori, TAKAGI Ritsuo

    Jpn. J. Oral. Maxillofac. Surg.   54 ( 9 )   541 - 545   2008.9

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    We describe an 88-year-old woman with gas-forming submental cellulitis in whom nonsteroidal antiinflammatory drug (NSAID)-induced gastric ulcer led to hemorrhagic shock during treatment of an odontogenic infection. Hemodynamic treatment had to take priority, and intensive treatment for inflammation could not be performed. This apparently led to the development of descending necrotizing mediastinitis. During the six days of hospitalization, she took a total of 6 tablets of loxoprofen sodium (60 mg) and 1 diclofenac sodium suppository (25 mg) for analgesia after treatment.&lt;BR&gt;Retrospectively, if decisive and aggressive treatment for inflammation had been performed earlier after hospitalization, inflammation may have resolved sooner. Our experience reconfirms that the initial treatment of odontogenic infection is extremely important in very elderly patients. Even if NSAIDs are received for a short period of time in small doses, gastrointestinal hemorrhage can occur, as in our patient. Patients at high risk for gastrointestinal ulcer should receive prophylactic treatment with cyclo-oxygenase 2 inhibitors orproton pump inhibitors.Generally, very elderly patients have a high risk of complications because of considerable age-related declines in physical ability and functional reserve of organs. Very cautious treatment is therefore necessary.

    DOI: 10.5794/jjoms.54.541

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  • Effects of Problem-based Learning Tutorial on Lifelong Learning Competence

    ONO Kazuhiro, YAGI Minoru, OHUCHI Akitsugu, UOSHIMA Katsumi, AJIMA Hisao, HAYASHI Takafumi, SAITO Isao, OKIJI Takashi, MAEDA Takeyasu

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   24 ( 2 )   145 - 149   2008.8

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    新潟大学歯学部歯学科では、5年次の4月から10月にPBLチュートリアルによる授業「顎顔面診断・治療学」を実施している。今回、PBLチュートリアルの教育効果を検証するために、授業開始前と終了後に、生涯学習能力に関する学生の自己評価を行い、その結果を比較した。対象は、平成18,19年度学生105名中95名である。学生には研究の目的、結果は成績評価に用いないこと、研究への協力は本人の自由意思によることを説明し、同意を得た。方法は、生涯学習能力に関する学習意欲、問題発見・解決能力、自己評価能力、コミュニケーション能力の11項目の方向目標を学生に明示し、評価基準について教員を含めクラス全員で討論した後に、内的基準を学生に個人的に設定させ、それに従い到達度を5段階で自己評価させた。その結果、自己評価能力についてはPBLチュートリアル前後で変化は認められなかったが、学習意欲、問題発見・解決能力、コミュニケーション能力は有意な上昇がみられた。以上のことから、PBLチュートリアルは生涯学習能力の育成に効果があると推察された。知識基盤社会を生き抜くこれからの歯科医師を養成するために、歯学教育におけるPBLチュートリアルの重要性は、ますます高まるものと考える。(著者抄録)

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  • Relapse tendency in maxillary arch width in unilateral cleft lip and palate patients with different maxillary arch forms Reviewed

    Talat Al-Gunaid, Toshikazu Asahito, Masaki Yamaki, Kooji Hanada, Ritsuo Takagi, Kazuhiro Ono, Isao Saito

    CLEFT PALATE-CRANIOFACIAL JOURNAL   45 ( 3 )   278 - 283   2008.5

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    Objective: The aim of this study was to investigate the relapse tendency in the maxillary dental arch widths in unilateral cleft lip and palate patients with different types of maxillary arch form.
    Subjects: Thirty-two unilateral cleft lip and palate patients treated by one-stage surgical palatal closure were included. The subjects were divided into three groups according to the types of the maxillary arch forms: group A, symmetrical arch form; group 13, collapse of minor segment; group C, collapse of both segments.
    Methods: Using dental casts obtained at three different times, relapse in the intercanine, interpremolar, and intermolar widths in each group was assessed and differences between groups were investigated.
    Results: Patients in group A showed stable results in all measurements. Patients in group B showed posttreatment relapse in the intercanine width only, whereas patients in group C demonstrated significant posttreatment relapses in the interpremolar and intermolar widths. Comparison between groups showed more significant relapse in the interpremolar and intermolar widths of group C than in those of group B.
    Conclusion: The types of the maxillary arch forms in unilateral cleft lip and palate patients might play a stronger role in the stability of the maxillary dental arch widths after orthodontic treatment in patients with collapse of both segments and a severe degree of maxillary narrowness.

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  • Developmental Changes of the Nasal form in Patients with Unilateral Cleft Lip and Palate

    FURUSATO Miyuki, MORITA Shuichi, ASAHITO Toshikazu, ONO Kazuhiro, TAKAGI Ritsuo, SAITO Chikara, SAITO Isao

    J.Jpn.Cleft Palate Assoc.   33 ( 1 )   42 - 56   2008.4

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    Objectives: The purpose of this study was to investigate long-term developmental changes of nasal form in patients with complete unilateral cleft lip and palate (UCLP).&lt;BR&gt;Subjects and Methods: The subjects comprised 11 boys and 10 girls with UCLP (CL group) born between 1982 and 1990 who had undergone two-stage palatal closure along with Hotz&#039; plate. Control subjects were composed of 10 boys and 10 girls without UCLP (NCL group) who had undergone the first phase of orthodontic treatment for anterior crossbite when aged between 8 to 10 years. Lateral cephalograms taken between 8 and 14 years old were divided into four age groups of 8,10,12 and 14 years old. After lateral cephalograms were traced, they were superimposed on various structures of the frontal cranial base. The FH plane was selected as a reference line, and then angular and linear measurements were performed.&lt;BR&gt;The results were as follows:&lt;BR&gt;1. The horizontal position of the maxilla in the CL group was more posterior for both boys and girls than that in the NCL group, indicating the tendency toward maxillary deficiency.&lt;BR&gt;2. In terms of nasal appearance in soft tissue profile, while the CL group had a backward positioned nose compared with the NCL group, there was no statistical significance in nasal height (Pn-Sn) between the CL and NCL groups in both boys and girls.&lt;BR&gt;3. As for nasal form, dorsal angle of the nose (&amp;ang; 1) and curvature of the nasal base (&amp;ang; 4) were significantly small and large respectively, for both boys and girls in the CL group compared with the NCL group.&lt;BR&gt;4. The horizontal and vertical positions of the nasal bone and the maxilla to the cranial base may be associated with nasal form.&lt;BR&gt;5. Changes in the amount of the nasal apex every two years were less than one degree for both boys and girls, suggesting that the shape of the nasal apex is maintained in children of the ages observed.

    DOI: 10.11224/cleftpalate1976.33.1_42

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  • Staff recruitment, development and global mobility

    E. Corbet, J. Akinwade, R. Duggal, G. Gebreegziabher, H. Hirvikangas, D. Hysi, L. Katrova, T. Karaharju-Suvanto, C. McGrath, K. Ono, M. Radnai, E. Schwarz, J. Scott, J. -L. Sixou, U. Soboleva, K. Uoshima, K. Yaneva-Ribagina, C. Fox

    EUROPEAN JOURNAL OF DENTAL EDUCATION   12   149 - 160   2008.2

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    This paper considers issues that relate to staff recruitment, staff development and global mobility of dental academics. Published literature, which has a North American bias, is reviewed. Recommendations, which may be applicable world-wide, are made to address evident and pertinent areas of concern in terms of the availability of quality dental teaching staff in dental teaching institutions so as to sustain the global dental academic enterprise at appropriately high levels of achievement.

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  • Correction of mandibular asymmetry due to hemifacial microsomia using a custom-made implant Reviewed

    Kodama Y, Fukuda J, Watanabe N, Nishiyama H, Ono K, SAITO I, Takagi R

    Asian J Oral Maxillofacial Surg   20 ( 4 )   204 - 208   2008

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  • Clinical Evaluation of Tongue Flap for residual oro-nasal Fistula after the Palatoplasty for Patients with Cleft Lip and Palate

    TAKAGI Ritsuo, IIDA Akihoko, ONO Kazuhiro, TERAO Emiko

    日本頭蓋顎顔面外科学会誌 = Journal of the Japan Society of Cranio-Maxillo-Facial Surgery   23 ( 4 )   263 - 271   2007.12

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    硬口蓋裂術後の残遺孔に対し舌弁による閉鎖術を施行した12例について臨床的検討を行った。1)性別は男女各6例で、手術時年齢は15〜23歳(平均19.3歳)であった。2)口蓋部の残遺孔の発生は、両側性7例、片側性4例、口蓋裂1例で、両側性に多かった。3)手術法はpushback法が11例、二段階法が1例であった。4)残遺孔の部位は切歯孔部に関連する症例が10例、硬口蓋正中部などの比較的後方に認める症例が2例で、残遺孔による障害はほとんどが鼻漏であった。5)舌弁により残遺孔が完全閉鎖された症例は7例、術後に形態修正術、顎裂部腸骨移植術などで二次的に閉鎖した症例が3例あり、結果的に10例(83.3%)で完全閉塞が得られた。尚、最終的に2例では小さな瘻孔が残ったが、鼻漏れなどの障害は認められなかった。

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  • Effects of Secondary Bone Grafting Period on Growth and Development in Dentofacial Complex in Patients with Complete Unilateral Cleft Lip and Palate

    USUI Yukiko, ONO Kazuhiro, ASAHITO Toshikazu, KOCHI Shoko, TAKAGI Ritsuo, SAITO Isao, YAGI Minoru

    J.Jpn.Cleft Palate Assoc.   32 ( 3 )   283 - 298   2007.10

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    Objectives: The purpose of this study was to investigate the effects of the timing of secondary bone grafting on the growth and development of dentofacial complex in patients with complete unilateral cleft lip and palate (UCLP).&lt;BR&gt;Design: Retrospective lateral cephalometric study.&lt;BR&gt;Interventions: Thirty patients received similar primary surgical procedures by the same surgeon and the similar first phase orthodontic treatment. These patients were divided into two groups according to their age at secondary bone grafting: 23 patients at a mean age of 9.6 years (early group) and 7 at a mean age of 12.2 years (late group).&lt;BR&gt;Methods: Lateral cephalometric radiographs of all subjects were obtained at two different times: at the age of 7 or 8 years (prior to bone grafting) and at the age of 15 or 16 years (more than one year after bone grafting). Twenty-eight measurement items on the sagittal and vertical growth of viscerocranium were compared between the early and late groups by the unpaired t-test.&lt;BR&gt;Results and discussion: Vertical maxillary growth was inhibited significantly in the early group in comparison with the late group; however, there was no significant difference in sagittal maxillary growth between the two groups. This suggests that sagittal anterior maxillary growth is almost completed before the age of 10 years, but the alveolar process is still growing vertically after the age of 10 years.

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  • 口唇口蓋裂患者における上顎狭窄歯列弓の側方拡大 Surgically Assisted Maxillary Expansionの応用

    小野 和宏, 小林 正治, 齊藤 力, 福田 純一, 高木 律男, 朝日藤 寿一, 竹山 雅規, 齋藤 功

    日本顎変形症学会雑誌   17 ( 3 )   206 - 212   2007.8

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    上顎歯列弓の狭窄に対してLe Fort I型骨切り術を用いたsurgically assisted maxillary expansion(SAME)を行った口唇口蓋裂8例を対象とし、術式ならびにその利点、欠点について検討した。6例は第I期歯科矯正治療で側方拡大を行い後戻りした既往があった。手術時間は平均87分で、出血量は平均218gであった。術中、術後の合併症はなかった。平均45日間の待機期間後、1日0.4〜1mmの速度で拡大を行い、6〜11mmと全例で予定通りの拡大量が得られた。術後3ヵ月からX線写真で骨延長部に新生骨が確認できた。拡大装置による保定期間は平均94日間で、その後にquad-helixを装着し、歯の移動を開始した。SAMEは容易で、確実に歯列弓の拡大が行え、口唇口蓋裂患者の上顎狭窄歯列弓の治療に有用な方法であることが示唆された。

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  • Cleft Palate Team Activities in Niigata University Medical and Dental Hospital (Dental Section)

    TERADA Kazuto, ASAHITO Toshikazu, ONO Kazuhiro, YAGI Minoru, YOSHIBA Kunihiko, KOBAYASHI Tadaharu, IIDA Akihiko, SAKURAI Naoki, TAKEISHI Hideyuki, MOHRI Tamaki, MATSUYAMA Junko, TANAKA Rei, SEO Kenji, TERAO Emiko, CHINO Yuhko, YOSHIOKA Setsuko, OHUCHI Akitsugu, KITAMURA Eriko, SAITO Isao, SAITO Chikara, KODAMA Yasumitsu, TAKAGI Ritsuo, KAZKI Reiko

    日本口蓋裂学会雑誌   32 ( 1 )   43 - 56   2007.4

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  • An evaluation of problem-based learning course at Niigata University Faculty of Dentisitry Invited Reviewed

    Maeda T, Ono K, Ohuchi A, Hayashi T, Saito I, Okiji T, Uoshima K

    Dentistry in Japan   43   166 - 171   2007

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  • Introduction of Mini-workshop in an Aptitude Test for Dental Residents at Niigata University Medical and Dental Hospital

    KOBAYASHI Tetsuo, UOSHIMA Katsumi, FUJII Noritaka, NAKAJIMA Takako, ISHIZAKI Hiroko, ONO Kazuhiro, MIYAZAKI Hideo

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   22 ( 3 )   281 - 288   2006.12

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    本研究の目的は、臨床研修歯科医採用試験においてミニワークショップによる評価が有効か否かを検討することである。平成16年12月、新潟大学医歯学総合病院歯科医師臨床研修を希望する者35名を5グループに編成して自由討論を行わせ、5名の評価者がローテーションにより各グループ受験者の態度・コミュニケーション能力を評価した。その後、ミニワークショップによる評価の妥当性を探るためにアンケート調査(受験者・評価者対象)を実施して分析を行うとともに、各試験成績間およびこれらと1年間の臨床研修総括評価との相関について検索した。その結果、1)採用試験の一部としてのミニワークショップは運営上効率的であり、アンケート調査結果からミニワークショップは情意領域の評価に有効であることが示された。2)ミニワークショップ成績は小論文成績と正の相関を示したが、実技成績とは相関がなかった。3)ミニワークショップ成績は臨床研修における情意および認知領域での総括評価と強い正の相関を示した。以上より、ミニワークショップは臨床研修歯科医採用試験での臨床能力評価において有効であり、情意領域のみでなく認知領域の評価をもある程度代替できる可能性が示唆された。今後は評価基準の検討によりさらに信頼性を高める必要がある。(著者抄録)

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  • A Longterm Follow-up Study of Two-stage Palatoplasty/Hotz Plate Approach for Patients with Unilateral Cleft Lip and Palate : A Morphological Evaluation with Lateral Cephalograms at More than 15 Years of Age

    TAKAGI Ritsuo, FUKUDA Jun-ichi, ONO Kazuhio, IIDA Akihiko, ASAHITO Toshikazu, TERADA Kazuto, SAITO Isao

    日本口蓋裂学会雑誌   31 ( 3 )   245 - 252   2006.10

  • Localization of CD44 and hyaluronan in the synovial membrane of the rat temporomandibular joint Reviewed

    Akiko Suzuki, Kayoko Nozawa-Inoue, Norio Amizuka, Kazuhiro Ono, Takeyasu Maeba

    Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology   288 ( 6 )   646 - 652   2006.6

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    Previous studies have pointed out a lack of adhesion structures in the synovial lining layer of the rat temporomandibular joint (TMJ) despite showing an epithelial arrangement. CD44, a major cell adhesion molecule, plays crucial roles as an anchor between cells and extracellular matrices by binding hyaluronan (HA) for the development of organs or the metastasis of tumors. The present study examined the localization of CD44 in the synovial membrane of the rat TMJ by immunocytochemistry for OX50, ED1, and Hsp25, which are markers for the rat CD44, macrophage-like type A, and fibroblast-like type B synoviocytes, respectively. Histochemistry for HA-binding protein (HABP) was also employed for the detection of HA. OX50 immunoreactions were found along the cell surface and, in particular, accumulated along the surface of the articular cavity. Observations by a double immunostaining and immunoelectron microscopy revealed that all the OX50-immunopositive cells were categorized as fibroblastic type B cells, which had many caveolae and a few vesicles reactive to intense OX50. However, the macrophage-like type A cells did not have any OX50 immunoreaction in the synovial lining layer. A strong HABP reaction was discernable in the extracellular matrix surrounding both OX50-positive and -negative cells in the synovial lining layers, exhibiting a meshwork distribution, but weak in its sublining layer. This localization pattern of CD44 and HABP might be involved in the formation of the epithelial arrangement of the synovial lining layer. Furthermore, OX50 immunonegativity in the type A cells suggests their low phagocytotic activity in the rat TMJ under normal conditions. © 2006 Wiley-Liss, Inc.

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  • Localization of CD44 and hyaluronan in the synovial membrane of the rat temporomandibular joint Reviewed

    A Suzuki, K Nozawa-Inoue, N Amizuka, K Ono, T Maeda

    ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY   288A ( 6 )   646 - 652   2006.6

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    Previous studies have pointed out a lack of adhesion structures in the synovial lining layer of the rat temporomandibular joint (TMJ) despite showing an epithelial arrangement. CD44, a major cell adhesion molecule, plays crucial roles as an anchor between cells and extracellular matrices by binding hyaluronan (HA) for the development of organs or the metastasis of tumors. The present study examined the localization of CD44 in the synovial membrane of the rat TMJ by immunocytochemistry for OX50, ED1, and Hsp25, which are markers for the rat CD44, macrophage-like type A, and fibroblast-like type B synoviocytes, respectively. Histochemistry for HA-binding protein (HABP) was also employed for the detection of HA. OX50 immunoreactions were found along the cell surface and, in particular, accumulated along the surface of the articular cavity. Observations by a double immunostaining and immunoelectron microscopy revealed that all the OX50-immunopositive cells were categorized as fibroblastic type B cells, which had many caveolae and a few vesicles reactive to intense OX50. However, the macrophage-like type A cells did not have any OX50 immunoreaction in the synovial lining layer. A strong HABP reaction was discernable in the extracellular matrix surrounding both OX50-positive and -negative cells in the synovial lining layers, exhibiting a meshwork distribution, but weak in its sublining layer. This localization pattern of CD44 and HABP might be involved in the formation of the epithelial arrangement of the synovial lining layer. Furthermore, OX50 immunonegativity in the type A cells suggests their low phagocytotic activity in the rat TMJ under normal conditions.

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  • Introduction of Problem-based Learning into the Undergraduate Education at the Niigata University Faculty of Dentistry

    ONO Kazuhiro, OHUCHI Akitsugu, UOSHIMA Katsumi, HAYASHI Takafumi, NISHIYAMA Hideyoshi, AJIMA Hisao, KOBAYASHI Tadaharu, SEO Kenji, SAITO Isao, CHENG Jun, YAMADA Yoshiaki, MAEDA Takeyasu

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   22 ( 1 )   58 - 71   2006.4

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    新潟大学歯学部歯学科では平成16年度より5年次の授業にPBLテュートリアルを導入した.1年次に教えられる学習から自ら学ぶ学習態度への転換,またその学習法としてのスタディ・スキルズを習得させ,3年次に医学教育開発研究センター主催の「楽位置楽The Tutorial」への参加によりPBLの原理を理解させた後に,部分的折衷型カリキュラムで実施している.このPBLテュートリアルは,4年次までに学習した基礎科学と臨床歯学の知識を統合させ,疾患概念を構築し,治療の原則を理解すること,また臨床実習前に,医療人としての在り方を深く考えさせることを教育の目標とし,基礎および臨床の8分野が参加している.このカリキュラムで学習した平成16,17年度5年生,計107名のアンケート結果では,約9割の学生がPBLテュートリアルをこれからの歯科医師としてのキャリアに重要と捉えていた.また,約8割の学生がPBLテュートリアルでの学習を有意義と感じており,科目別の知識の統合と理解の深化,学習意欲の高まり,問題発見・解決能力や対人関係能力の向上を自覚していた.PBLテュートリアルの実施にあたっては,学習内容と量を十分に検討し,それに見合う自習時間を確保すること,また,学生主体の学習を補う支援授業の開催や,学習を促進させる教員の養成が重要と考えられた(著者抄録)

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  • Blepharo-cheilo-dontic (BCD) syndrome: Case report Reviewed

    A Iida, S Narai, R Takagi, K Ono, N Ikeda

    CLEFT PALATE-CRANIOFACIAL JOURNAL   43 ( 2 )   237 - 243   2006.3

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    Objective: To report a case of blepharo-cheilo-dontic (BCD) syndrome, to compare with the previous cases, and to discuss the possible treatment.
    Patient: The patient was a 14-day-old boy born uneventfully on August 7, 2002. His scalp hair was sparse and curly. A tumor on the top of his head, which was thought to be a dermoid cyst, and a nevus on the back of his left hand were observed. All typical symptoms of blepharo-cheilo-dontic syndrome, such as euryblepharon with ectropion of the lower eyelids, distichiasis, bilateral cleft lip and palate, severe oligodontia, and conical teeth, were observed. Because there was no fatal complication, and growth and development were about normal, it was recommended that a long and active treatment plan be considered for this patient.

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  • Two cases of mandibular hypomobility in an infant

    AJIMA Hisao, TAKAGI Ristuo, IMAI Nobuyuki, ONO Kazuhiro, IIDA Akihiko, ARASHIYAMA Takanori

    小児口腔外科 = Pediatric oral and maxillofacial surgery   15 ( 2 )   118 - 124   2005.12

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    It is necessary for dentists to control the mandibular hypomobility in children even if it happens relatively rarely. In this case report, we present two different causes for limitation of mouth opening.<BR>They have morphological abnormalities in their unilateral masticatory muscles on the CTs, but there is no abnormal finding around their temporomandibular joints. Case 1 is a 3 year-old boy who had a history of cranial operations several times due to multi-located brain vascular malformations. On his CTs, atrophic changes were detected in some masticatory muscles that were controlled under facial and trigeminal nerves. Case 2 is a one-year old boy who has a congenital wryneck. His temporal muscle reveals hypertrophy on his CTs. Dystonia of masticatory muscle was suspected from these findings as well as his sternocleid muscle of his wryneck. At the present time, it is very difficult to detect in detail such as electro-myographies about their pathology because of his younger age. Therefore, we will observe his oral conditions and follow up for a long time.

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  • 進行性顔面片側萎縮症の歯科矯正外科治療(Progressive Hemifacial Atrophy Treated by Orthodontic Surgery)

    Kodama Yasumitsu, Miyazawa Marta, Fukuda Jun-ichi, Iida Akihiko, Ono Kazuhiro, Takagi Ritsuo

    Oral Science International   2 ( 2 )   131 - 135   2005.11

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    進行性顔面片側萎縮症(PHA)は顔面の片側に生じる自己限定的な皮下組織萎縮であり,硬組織性は稀である.散発性の緩徐進行性疾患であり,病因については不明である.基本的に,PHA(通常は軟部組織)による顔面非対称治療は容積増強術によって行われる.硬組織PHAの稀症例について述べた.症例は15歳男児であった.左大臼歯,上顎および下顎に萎縮性変化が生じ,中程度の軟部組織萎縮が伴っていた.口部は右側上方に傾斜し,正常咬合にも関らず咬合平面は重度に傾斜していた.萎縮性変化および進行の停止を認めた後に,歯科矯正手術を行った.咬合平面および顔面非対称を矯正するために,Le Fort Iおよび両側下顎枝垂直骨切術を行った.3年後の追加調査では,咬合平衡は良好で,顔面対称性も改善し,萎縮再発は認められなかった.このように,中程度の軟部組織萎縮を伴う硬組織萎縮の第一手段として,歯科矯正外科は有効であった

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  • A case of deep venous thrombosis after orthognathic surgery in a young adult

    TSUBATA Kumiko, FUKUDA Jun-ichi, FUJITA Hajime, AJIMA Hisao, ONO Kazuhiro, TAKAGI Ritsuo

    Jpn. J. Oral. Maxillofac. Surg.   51 ( 10 )   520 - 523   2005.10

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    Deep venous thrombosis (DVT) is caused by obstruction of blood flow of the deep vein of the leg and accelerated blood coagulating activity. DVT may occur after an operation. However, there are few reports of DVT associated with surgery of the oral and maxillofacial region, especially in young adults.&lt;BR&gt;We report a case of DVT occurring after orthognathic surgery in a 19-year-old woman at our hospital. She had facial asymmetry and underwent Le Fort I osteotomy of the maxilla combined with sagittal splitting ramus osteotomy and intraoral vertical ramus osteotomy of the mandible under general anesthesia. Although she was able to walk the next day, symptoms of DVT appeared 3 days after the operation. On the 18th day after the first operation, surgery to remove the thrombus was performed by cardiovascular surgeons. She was discharged on the 34th day after the first operation.&lt;BR&gt;Orthognathic surgery is not free of the risk of DVT, which can cause fatal acute pulmonary thromboembolism. Therefore, it is necessary to prevent DVT after orthognathic surgery, even in young adults.

    DOI: 10.5794/jjoms.51.520

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  • Development of the articular cavity in the rat temporomandibular joint with special reference to the behavior of endothelial cells and macrophages Reviewed

    Akiko Suzuki, Kayoko Nozawa-Inoue, Nobuyuki Ikeda, Norio Amizuka, Kazuhiro Ono, Ritsuo Takagi, Takeyasu Maeda

    Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology   286 ( 2 )   908 - 916   2005.10

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    Previous developmental studies on the temporomandibular joint (TMJ) have proposed several hypotheses on the formation of its articular cavity. However, detailed information is meager. The present study examined the formation process of the articular cavity in the rat TMJ by immunocytochemistry for CD31, RECA-1, and ED1, which are useful cellular markers for endothelial cells and monocyte/macrophage lineages, respectively. The upper articular cavity formation had begun by embryonic day 21 (E21) and was completed at postnatal day 1 (P1) in advance of the lower cavitation
    the latter took place from P1 to P3. The occurrence and distribution pattern of the CD31-, RECA-1-, and ED1-positive cells differed between the upper and lower articular cavity-forming areas: the ED1-positive cells exclusively occurred in the area of the prospective upper articular cavity prior to its formation, while no ED1-positive cell appeared in the lower cavity-forming area. In contrast, the CD31- and RECA-1-positive endothelial cells were restricted to the lower cavity-forming area (never the prospective upper cavity) at E19 and diminished thereafter. Throughout the cavity formation, we failed to find any apoptotic cells in the cavity formation area, indicating no involvement of apoptosis in the cavity formation in TMJ. The present findings on the behaviors of endothelial cells and ED1-positive cells show a possibility of different mechanism in the cavity formation between the upper and lower articular cavities in the rat TMJ. The appearance of ED1-reactive cells and temporal vascularization may play crucial roles in the upper and lower articular cavity formation, respectively. © 2005 Wiley-Liss, Inc.

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  • Development of the articular cavity in the rat temporomandibular joint with special reference to the behavior of endothelial cells and macrophages Reviewed

    A Suzuki, K Nozawa-Inoue, N Ikeda, N Amizuka, K Ono, R Takagi, T Maeda

    ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY   286A ( 2 )   908 - 916   2005.10

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    Previous developmental studies on the temporomandibular joint (TMJ) have proposed several hypotheses on the formation of its articular cavity. However, detailed information is meager. The present study examined the formation process of the articular cavity in the rat TMJ by immunocytochemistry for CD31, RECA-1, and ED1, which are useful cellular markers for endothelial cells and monocyte/macrophage lineages, respectively. The upper articular cavity formation had begun by embryonic day 21 (E21) and was completed at postnatal day 1 (P1) in advance of the lower cavitation; the latter took place from P1 to P3. The occurrence and distribution pattern of the CD31-, RECA-1-, and ED1-positive cells differed between the upper and lower articular cavity-forming areas: the ED1-positive cells exclusively occurred in the area of the prospective upper articular cavity prior to its formation, while no ED1-positive cell appeared in the lower cavity-forming area. In contrast, the CD31- and RECA-1-positive endothelial cells were restricted to the lower cavity-forming area (never the prospective upper cavity) at E19 and diminished thereafter. Throughout the cavity formation, we failed to find any apoptotic cells in the cavity formation area, indicating no involvement of apoptosis in the cavity formation in TMJ. The present findings on the behaviors of endothelial cells and ED1-positive cells show a possibility of different mechanism in the cavity formation between the upper and lower articular cavities in the rat TMJ. The appearance of ED1-reactive cells and temporal vascularization may play crucial roles in the upper and lower articular cavity formation, respectively. (C) 2005 Wiley-Liss, Inc.

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  • Spontaneous size-reduction of residual cleft and the results of hard palate closure after soft palate repair by Furlow method in two-stage palatoplasty

    IIDA Akihiko

    日本口蓋裂学会雑誌   30 ( 2 )   70 - 70   2005.4

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  • 垂直的歯槽骨延長法を用いて顎堤形成を行った1例

    小野 和宏, 小林 正治, 安島 久雄, 高木 律男, 毛利 環, 橋本 明彦, 田中 礼

    新潟歯学会雑誌   34 ( 2 )   219 - 224   2005.1

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    17歳女.9歳時に中心性血管腫の診断にて輸入血管塞栓術後に下顎骨部分切除術を施行された.咀嚼障害と審美障害を主訴に顎堤形成目的で来診した.両側中切歯・側切歯・犬歯の6歯を含め下顎骨が切除されていたため,歯槽骨欠損に対してプレート型延長装置を用いて垂直的歯槽骨延長法を施行した.その結果,延長装置は小型で患者にとって違和感がなく,感染など合併症も認められず,形成された顎堤は高さ・幅共に良好でインプラントにより機能的にも審美的にも満足いく咬合が再建された.以上より垂直的歯槽骨延長法は従来の骨移植と比較して術式が簡単かつ安全で,骨の採取不用・術後の骨吸収が少ない・骨延長に制限がない・骨周囲の骨膜や軟組織も延長するなど多くの利点を有し,歯槽骨欠損に対する有用な治療方法であるものと考えられた

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  • Introduction of Problem-Based Learning (PBL) into Dental Educational Programs at Niigata University Faculty of Dentistry : A Survey of the PBL Program at the University of Southern California School of Dentistry

    AJIMA Hisao, ONO Kazuhiro, MAEDA Takeyasu, NAGATA Masaki, TAKAGI Ritsuo, YAMADA Yoshiaki, OKIJI Takashi, UOSHIMA Katsumi, YOSHIHARA Akihiro, HANADA Kooji

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   20 ( 1 )   166 - 173   2004.12

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    2001年12月に新潟大学の教員6名が南カリフォルニア大学歯学部を訪れ,米国人学生とともにPBL(問題解決型学習)教育を1週間体験した.また,PBLの概念,教科課程編成法,教材の作成法,評価方法などについて資料収集を行った.その結果,PLBでは問題への解答よりも学習者中心の問題解決過程を通じた理解の育成が重視されること,教員の役割は知識の伝授ではなくグループの作業プロセスを支援して学習目標への到達を促すものであることなどが確認された

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  • Mandibular Alveolar Ridge Augmentation Using Distraction Osteogenesis: A Case Report

    Ono Kazuhiro, Kobayashi Tadaharu, Ajima Hisao

    Niigata dental journal   34 ( 2 )   55 - 60   2004.12

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    Vertical alveolar distraction was first described by Chin and Toth in 1996. This method is an alternative procedure for augmentation of the alveolar ridge. A segmental osteotomy mobilizes the bone for transport. By using controlled, gradual distraction, it is possible to enlarge the segment of the bone and reconstruct the alveolar ridge. This paper presented our first experience with alveolar ridge distraction in a patient with a bone defect after segmental resection in tumor surgery. An internal distraction device (LEAD system(R), LEIBINGER) was used. This device achieved patient acceptability and comfort. Distraction osteogenesis was successfully done to correct the alveolar process deficiency without any complications. Correction of the site of deficiency made it possible to rehabilitate the dentition using osseointegrated implants. Vertical alveolar distraction seems to have many advantages compared with autogenous onlay bone grafting. The advantages are as follows ; easy and safe technique, no donor site morbidity, less bone resorption, no limitation of distraction, expanding the overlying soft tissue while distraction osteogenesis.垂直的歯槽骨延長法は、1996年にChin and Tothにより初めて報告された顎堤形成法である。骨切りした歯槽骨片を延長装置により徐々に上方に移動させ、骨断端間に新たな骨を再生させることにより、顎堤の高さを回復する。今回、腫瘍切除後の歯槽骨欠損に対して、プレート型延長装置(LEIBINGER社製LEADシステム(R))を用いて、垂直的歯槽骨延長法を施行した1例を経験した。延長装置は小型で、患者にとって違和感はなく、また、感染などの合併症は認められなかった。形成された顎堤は高さ、幅ともに良好で、インプラントにより機能的にも審美的にも満足いく咬合を再建可能であった。垂直的歯槽骨延長法は、これまでおもに行われてきた骨移植と比較して、術式が簡単で安全、骨の採取が不要、術後の骨吸収が少ない、骨延長量に制限がない、骨周囲の骨膜や軟組織も延長するなどさまざまな利点を有し、歯槽骨欠損に対する有用な治療方法と考えられた。

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  • Linkage analysis between BCL3 and nearby genes on 19q13.2 and non-syndromic cleft lip with or without cleft palate in multigenerational Japanese families Reviewed

    H Fujita, M Nagata, K Ono, H Okubo, R Takagi

    ORAL DISEASES   10 ( 6 )   353 - 359   2004.11

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    OBJECTIVE: To investigate the linkage between candidate genes on chromosome 19 and cleft lip with or without cleft palate in Japanese using a parametric method.
    MATERIALS AND METHODS: After informed consent was obtained, blood samples were drawn from 90 individuals in 14 families, 30 of whom were affected, and genomic DNAs were extracted. PCR-amplified products using four microsatellite markers, D19S178, BCL3, APOC2[007/008] and APOC2[AC1/AC2] located in 19q13.2, were separated by 8% polyacrylamide gel electrophoresis. Linkage analysis was carried out using the MLINK and LINKMAP programs, and logarithm of odds (LOD) scores were calculated for each family.
    RESULTS: Before undertaking linkage analysis, we analyzed 74 healthy Japanese subjects and found racial differences in that the observed number of alleles and their heterozygosity were lower in Japanese than in Caucasians, and that both populations tended to show a different allele distribution. In 14 families, two-point maximum LOD score (Z(max)) for BCL3 was 0.341 and multi-point Z(max) was less than -2 excluding linkage. But in 9 families with left and bilateral CL/P, two-point Z(max) for APOC2[AC1/AC2] was 1.701 and multi-point Z(max) at APOC2 locus was 1.909.
    CONCLUSION: The LOD score was relatively high but provided no evidence of linkage for CL/P to BCL3 and nearby genes in Japanese subjects.

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  • 晩期成長による再発が疑われた下顎非対称の1例

    児玉 泰光, 福田 純一, 藤田 一, 安島 久雄, 小野 和宏, 高木 律男

    日本口腔外科学会雑誌   50 ( 7 )   422 - 425   2004.7

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    症例は14歳女子で,12歳時に顎矯正手術適応と診断され,成長のスパートまで経過観察となった.14歳時,術前矯正治療開始時期と判断され来院,画像所見では上下顎とも正中に対し左側偏位を認め,偏位量はオトガイ部12mm,下顎前歯正中9mm,上顎前歯正中4.5mmで,骨格性下顎前突を呈していた.下顎非対称による下顎前突症と臨床診断し,術前矯正治療後に下顎枝垂直骨切り術を施行,オトガイの左側偏位と下顎の前突,咬合関係は改善した.術後5年8ヵ月を経過し,成長に伴い下顎の左側偏位と左側臼歯部の交叉咬合が著明となり再診した.画像所見で前回同様に上下顎とも正中に対し左側偏位を認め,偏位量はオトガイ部14mm,下顎前歯正中9mm,上顎前歯正中4.5mmで,晩期成長による下顎非対称再発の臨床診断にて,術前矯正治療後に下顎枝矢状分割術+Miniplateによる骨接合術を施行した.その結果,オトガイ部は顔面正中に位置し上下顎前歯正中も一致し,術後2年の現在も咬合関係は安定している

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  • 2人乗り自転車前転事故による小児顎関節突起完全骨折の2例

    小林 孝憲, 高木 律男, 小野 和宏, 飯田 明彦, 碓井 由紀子, 安島 久雄

    日本口腔外科学会雑誌   50 ( 4 )   231 - 234   2004.4

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    症例1は5歳で,閉口不能を主訴とした.石につまずき前のめりに転倒し,オトガイ部を路面に強打した.正貌にてオトガイ正中に裂創を認め,左側頬部に顎角部にびまん性に腫脹していた.左側顎関節突起は完全骨折し,下内方へ転位していた.経口摂食困難であったため経鼻栄養チューブを挿入し,囲繞結紮術を施行した.術後8ヵ時での顎運動障害,顎関節部の疼痛や雑音は認めていない.症例2は2歳男で,オトガイ部を路面に強打した.下顎頭が両側ともに内方へ大きく脱臼し,右側関節突起では内側皮質骨の連続が認められたが左側は完全骨折であった.囲繞結紮術を施行し,術後1年で右側はほぼ正常下顎頭と同様の形態を示し,左側では内方と外方へ突起を伸ばした双頭下顎頭の形態を呈した

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  • 日本人口唇・口蓋裂患者における分子遺伝学的研究

    藤田 一, 永田 昌毅, 小野 和宏, 飯田 明彦, 碓井 由紀子, 児玉 泰光, 大久保 博基, 奈良井 省太, 小林 孝憲, 高木 律男

    新潟歯学会雑誌   33 ( 2 )   273 - 275   2004.1

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  • Long-term results of the two-stage palatoplasty/Hotz&apos; plate approach for complete bilateral cleft lip, alveolus and palate patients Reviewed

    AEQ Silvera, K Ishii, T Arai, S Morita, K Ono, A Iida, K Hanada, R Takagi

    JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY   31 ( 4 )   215 - 227   2003.8

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    Purpose: To investigate the effects of the two-stage palatoplasty combined with the Hotz&apos; plate on craniofacial development in patients with bilateral complete clefts. Material and methods: Lateral and frontal cephalograms of two-stage palatoplasty/Hotz&apos; plate group (n=10), one-stage palatoplasty group (n=11), and a non-cleft group (n=11), were evaluated at 6, 8, 10 and 12 years of age. The unpaired Student&apos;s t-test and Scheffe&apos;s F test (p&lt;0.05) were applied. Results: At 6 years the posterior upper facial height (PUFH) and PUFH/PFH ratio were greater in the two-stage group. At 10 years the PUFH, maxillary depth, convexity and ANB angle were greater in the same group. At 12 years, maxillary depth and ANB angle were also greater in this group. In the one-stage group, the L1/Mp. angle, PUFH and PUFH/PFH ratio were smaller when compared with the non-cleft group, whereas the palatal plane/SN angle was greater. In both cleft groups, the I.I. angle and tongue-PTM&apos; distance were greater, and the U1/SN angle was smaller when compared with non-clefts. The UC-UC&apos; and the ratios UC/MAX and UC/LC of both cleft groups were also smaller when compared with non-clefts. The ratio UM/MAX of the one-stage group was smaller when compared with the non-cleft group. Conclusion: The two-stage palatoplasty in combination with application of the Hotz&apos; plate had good effects on the maxillary growth up to the age of 12 years. (C) 2003 European Association for Cranio-Maxillofacial Surgery.

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  • 顎口腔領域癌患者における上部消化管内視鏡検査(GIF)の検討

    山中 正文, 飯田 明彦, 高木 律男, 小野 和宏, 星名 秀行, 藤田 一, 長島 克弘, 池田 順行, 福田 純一, 小林 龍彰

    日本口腔外科学会雑誌   49 ( 5 )   329 - 334   2003.5

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    顎口腔領域扁平上皮癌患者62例にGIFを行った.一般集団に比べて高頻度に異常所見が認められた.癌が6例(9.7%),前癌病変である食道異型上皮,Barret上皮が各3例(各4.8%),萎縮性胃炎が26例(41.9%),腸上皮化生が9例(14.5%),活動期の潰瘍性病変が4例(6.5%)に認められた.喫煙,飲酒の両方を常用する群は,いずれか一方或いはどちらも常用しない群に比べて食道病変有病率が有意に高かった

    DOI: 10.5794/jjoms.49.329

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  • Treatment of an ankylosed infraverted tooth by distraction osteogenesis : Report of a case

    ONO Kazuhiro, TAKAGI Ritsuo, IIDA Akihiko, FUKUDA Jun-ichi, MORITA Shuichi, ABE Yuuko

    Jpn. J. Oral. Maxillofac. Surg.   49 ( 4 )   295 - 298   2003.4

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    We describe the treatment of an ankylosed infraverted tooth by distraction osteogenesis after Epker&#039;s single-tooth dento-osseous osteotomy. There appear to be a number of advantages to this procedure, despite the high surgical invasiveness. This procedure is designed to correct malposition of ankylosed teeth and is more reliable than replantation or subluxation with orthodontic treatment, reported previously to be effective. Furthermore, malpositioned teeth can be transferred irrespective of distance and direction to their correct position. This procedure has a low risk of pulp devitalization and gingival recession. Distraction osteogenesis after single-tooth dento-osseous osteotomy may be a new useful method for treatment of tooth ankylosis.

    DOI: 10.5794/jjoms.49.295

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  • Introduction of OSCE for Assessment of Clinical Competence in Undergraduate Dental Education at Niigata University School of Dentistry

    OKIJI Takashi, FUKUSHIMA Masayoshi, YOSHIHARA Akihiro, KOTA Kohichi, ONO Kazuhiro, KOBAYASHI Hiroshi, UOSHIMA Katsumi, KOYAMA Jun-ichi, UEDA Koichiro, TAKAGI Ritsuo, MAEDA Takayasu, HANADA Kooji

    日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education   18 ( 2 )   300 - 307   2003.3

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    標記OSCEの概要を示し,試験成績とアンケート調査(受験者・評価者対象)の結果を報告した.OSCEは形成的評価に有効であった.低得点の試験課題の存在は,出題レベルの均一化の困難性を示すものであったが,これにより指導上の問題点も明らかになった.computer-based testingとの間に相関は認められなかった.評価者間の採点結果に有意差が認められたのは1ステーションのみで,試験の客観性は高いと考えられた.本試験法の継続的な実施には,熟練教官の養成を念頭に置いたOSCEの試行が不可欠と思われた.又,カリキュラムの中でのOSCEの位置づけをより明確なものとすることの必要性が示唆された

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  • Maxillary growth in patients, of ages five to twelve years, with bilateral cleft lip, alveolus, and palate treated by two-stage palatal repair combined with a Hotz's plate

    HAYATSU Makoto, ONO Kazuhiro, IIDA Akihiko, NAGATA Masaki, IMAI Nobuyuki, TAKAGI Ritsuo, OHASHI Yasushi, HANADA Kooji, MORITA Syuichi

    日本口腔科学会雜誌   52 ( 1 )   6 - 16   2003.1

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    The purpose of this study was to evaluate the effects of maxillary growth of patients with complete bilateral cleft lip and palate (BCLP) treated by twostage palatal repair combined with a Hotz's plate.<BR>The subjects were 26 BCLP patients from 5 to 12 years of age who had received two-stage palatal repair combined with a Hotz's plate (TSPR). Serial maxillary casts were used to analyze and compare with those of 34 BCLP treated by one-stage palatal repair (OSPR), and 24 normal children without any clefts (NC).<BR>The results were as follows:<BR>1. The length and width of the maxillary arch in the TSPR group were the same as for the NC group in patients from 5 to 6 years of age (before hard palate closure).<BR>2. From 7 to 12 years of age (after hard palate closure), the length of the maxillary arch grew gradually in the TSPR group, just like in the NC group. The maxillary width tended to be slightly smaller in the TSPR group than in the NC group. On the other hand, the incidence of cross bite in lateral dentition was lower in the TSPR group than in the OSPR group.<BR>It was concluded that two-stage palatal repair combined with a Hotz's plate was effective for maxillary growth in bilateral cleft lip and palate patients.

    DOI: 10.11277/stomatology1952.52.6

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  • Effects of Hotz' Plate-Based Two-Stage Palatoplasty on Craniofacial Development

    ARAI Toru, ISHII Kazuhiro, MORITA Shuichi, HANADA Kooji, ONO Kazuhiro, TAKAGI Ritsuo

    J. Jpn. Cleft Palate Assoc.   27 ( 3 )   306 - 324   2002.10

  • Clinical and Statistical Evaluation of Cleft Palate Team Activities at Niigata University Dental Hospital

    ASAHITO Toshikazu, TERADA Kazuto, ONO Kazuhiro, YAGI Minoru, KOBAYASHI Tadaharu, IIDA Akihiko, NOMURA Akiko, SATO Takahiro, YOSHIBA Nagako, TAI Hideaki, ISHII Kazuhiro, TAGUCHI Yo, KOBAYASHI Fukiko, SEO Kenji, TERAO Emiko, TAKAGI Ritsuo, HANADA Kooji

    日本口蓋裂学会雑誌   27 ( 3 )   297 - 305   2002.10

  • Monitoring of healing process of periodontal tissue after teeth autotransplantation by analysis of GCF components

    NUNOKAWA Yasuko, MURATA Masashi, ENDO Motohiro, WATANABE Kaku, YOSHIZAWA Michiko, KOBAYASHI Tadaharu, ONO Kazuhiro, SAITO Chikara, TAKAGI Ritsuo, YOSHIE Hiromasa

    日本歯科保存学雑誌   45   66 - 66   2002.10

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  • Longitudinal Observation of Maxillofacial Morphology in a Pair of Monozygotic Twins with Cleft Lip and Palate:Effects of Two -Stage Palatoplasty on Maxillofacial Development

    ONO Kazuhiro, HANADA Kooji, OCHI Kanako, MORITA Shuichi, IIDA Akihiko, HAYATSU Makoto, FUJITA Hajime, TAKAGI Ritsuo, ISHII Kazuhiro, ASAHITO Toshikazu

    J.Jpn.Cleft Palate Assoc.   27 ( 3 )   339 - 349   2002.10

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    The purpose of this study was to observe maxillofacial morphology of a pair of monozygotic twins with cleft lip and palate (Child 1) and cleft lip (Child 2) longitudinally, and to evaluate the effects of two-stage palatoplasty on maxillofacial development. The findings were as follows: 1. Compared with Child 2, th e position of the maxilla in Child 1 was already located posteriorly before the hard palate closure. Moreover, the posterior portion of the maxilla was located upward.2. Ther e was no difference in length of the hard palate between Child 1 and 2 before the hard palate closure. A little inhibition of maxillary growth was recognized in Child 1 operated on the hard palate closure.3. Clockwise ro tation of the mandible was observed in Child 1.4. The antero-posterior relationship between the maxilla and m andible was almost good in both Child 1 and 2. These findings s uggest that two-stage palatoplasty delaying hard palate closure does not severely inhibit growth of the alveolar portion of the maxilla, resulting in the achieving of a normal dental arch. In two-stage palatoplasty, this may cause a good inter-maxillary relationship owing to the help of morphological adaptation of the mandible, even if the position of the maxilla is posteriorly located.

    DOI: 10.11224/cleftpalate1976.27.3_339

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  • 上顎前方移動術が鼻咽腔に及ぼす影響について 口蓋裂症例の安静時X線による検討

    鍛冶 昌孝, 高木 律男, 星名 秀行, 福田 純一, 服部 幸男, 小野 和宏, 永田 昌毅, 飯田 明彦

    日本口腔外科学会雑誌   48 ( 10 )   501 - 504   2002.10

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    安静時の側方頭部X線規格写真をもとに口蓋裂症例の術前後の鼻咽腔形態の変化について,非口蓋裂症例を対照群として比較検討した.上顎の前方移動術により,口蓋裂群,対照群ともに咽頭の深さが増加した一方で,軟口蓋長の伸展,軟口蓋傾斜角の増加がみられ,軟口蓋-咽頭後壁間最短距離の変化は殆ど認められなかった.両群比較では口蓋裂群で軟口蓋長の伸長,咽頭の深さの増大が少なかった.瘢痕の強い症例では,前方移動量が5mm程度の場合,咽頭部の軟組織の変化が6割程度となることが示された

    DOI: 10.5794/jjoms.48.501

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  • 顎裂部への二次的骨移植に関する臨床統計的観察

    碓井 由紀子, 小野 和宏, 高木 律男, 永田 昌毅, 飯田 明彦, 今井 信行, 福田 純一, 藤田 一, 早津 誠, 寺尾 恵美子, 児玉 泰光, 青山 玲子

    新潟歯学会雑誌   32 ( 1 )   53 - 61   2002.7

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    Hotz床併用二段階口蓋形成術を施行した唇顎口蓋裂73例86顎裂(男児46例・女児27例,平均10.2歳;二段階群)と他院にて2歳以前に一期的に口蓋形成術が行われ,二次的顎裂部骨移植術を施行した唇顎口蓋裂20例22顎裂(男児12例・女児8例,平均11.9歳;一段階群)における術後早期成績について検討した.その結果,骨架橋形成は片側性唇口蓋裂では96.6%,両側性では全例に認められ,垂直的骨架橋が上顎中切歯および側切歯で平均歯根長が11mm以上のものが二段階群では片側性で84.7%,両側性で66.7%,一段階群では片側性62.6%,両側性33.3%で,片側性が有意に高かった.又,歯槽頂の高さは上顎中切歯歯根の3/4以上あるものが二段階群片側性88.1%,両側性77.8%,一段階群片側性56.3%,両側性なしと二段階群で有意に高かった.以上により二段階群は上顎切歯の歯軸の改善や側切歯・犬歯の萠出誘導に有利であると考えられた

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  • Linkage Analysis between Microsatellite Markers on Chromosome 19q13.2 and Non-syndromic Cleft Lip with or without Cleft Palate in Japanese Families

    FUJITA Hajime, NAGATA Masaki, ONO Kazuhiro, TAKAGI Ritsuo

    日本口腔科学会雜誌   15(1), 15-22 ( 1 )   15 - 22   2002.1

  • 最近10年間の新潟大学歯学部附属病院第二口腔外科入院患者の臨床統計学的検討

    青山 玲子, 高木 律男, 星名 秀行, 小野 和宏, 永田 昌毅, 飯田 明彦, 福田 純一, 小林 龍彰

    新潟歯学会雑誌   31 ( 2 )   153 - 157   2001.12

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    入院患者の動向と今後の改善点を把握することを目的に,10年間の入院患者について,臨床統計学的に検討した.その結果,入院患者総数は,3481人で,男女比は1:1であり,疾患別では,唇顎口蓋裂を中心とした奇形が1216人と最も多く,30歳未満が過半数であった.居住地別では,市内・佐渡を除く下越地方の患者が6割以上を占めていた.今後の展望として,入院施設を有効に利用するには,集学的な治療を活かすことを考慮し対象疾患を選択し,専門的な治療体制作りが必要である.治療体制整備の一環として,新潟県各地に入院施設を持つ病院歯科・口腔外科が新設されつつある中,広い範囲で各病院歯科との役割分担の確立も重要である

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  • Facial Morphology and Occlusion at the Stage of Early Mixed Dentition in Cleft Palate Patients Treated with Furlow Palatoplasty

    ONO Kazuhiro, ASAHITO Toshikazu, IMAI Nobuyuki, IIDA Akihiko, HAYATSU Makoto, TAKAGI Ritsuo, ISHII Kazuhiro, MORITA Shuichi, HANADA Kooji

    J.Jpn.Cleft Palate Assoc.   26 ( 1 )   23 - 30   2001.4

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    Facial morphology and occlusion at the stage of early mixed dentition in cleft palate patients treated with Furlow palatoplasty were examined and compared with patients treated with the pushback procedure. The subjects selected for this study were 15 patients with a cleft of the soft palate, who were divided into two different groups: The Furlow group consisted of 3 male and 5 female patients, whose cleft palates were repaired with Furlow double-opposing Z-plasty, at an average age of 1 year and 8 months, and the pushback group consisted of 2 male and 5 female patients, whose cleft palates were closed with the pushback procedure, at an average age of 1 year and 7 months.&lt;BR&gt;Cephalometric radiographs (mean age,8 years for the Furlow group, and 7 years and 11 months for the pushback group) and dental study casts (mean age,7 years and 10 months for the Furlow group, and 8 years for the pushback group) were analyzed. Six angles and 4 distances were measured in the cephalograms, and 9 measurements of dental arch width and 2 measurements of dental arch length, were obtained. The results indicated that midfacial growth was significantly better (angle ANB, angle NAPog, distance A&#039; -Ptm&#039; ) and upper dental arches were significantly larger (inter deciduous canine distance, inter first and second deciduous molar distances, dental arch length) in the Furlow group, compared with the pushback group. No subject in the Furlow group had crossbite, while in the pushback group,6 of 7 subjects had anterior and/or posterior crossbite. As Furlow palatoplasty avoids the need for a lengthening procedure that uses mucoperiosteal flaps from the hard palate, it could allow adequate maxillary growth.

    DOI: 10.11224/cleftpalate1976.26.1_23

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  • Evaluation of Secondary Bone Grafting Using Autogenous Particulate Cancellous Bone and Marrow-Harvested from Patients with Two-Stage Palatoplasty Combined with a Hotz Plate-Using CT-

    MORITA Shuichi, TORIKAI Yoko, ISHII Kazuhiro, WAKAMATHU Takanori, HANADA Kooji, ONO Kazuhiro, IIDA Akihiko, IMAI Nobuyuki, TAKAGI Ritsuo, KOBAYASHI Fukiko, HAYASHI Takafumi

    J. Jpn. Cleft Palate Assoc.   26 ( 1 )   114 - 124   2001.4

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    This study evaluated bone bridge formation after bone grafting using X-ray computed tomography, in complete unilateral cleft lip and palate patients. Subjects were 14 patients (5 females and 9 males), and all patients received two-stage palatoplasty combined with a Hotz plate, followed by bone grafting using autogenous particulate cancellous bone and marrow harvested from the iliac crest. X-ray computed tomography was performed before and after bone grafting (mean,3.6 months after), and an axial image was used. Then, both the shapes of cleft defects before bone grafting, and bone bridge formation after bone grafting, were classified into three types on basal and alveolar bone side level.&lt;BR&gt;Results were as follows:&lt;BR&gt;1) The cleft defect shape was classified into 5 types.1; on the basal and alveolar bone side, the anterior bone defect was larger than posterior (6 cases).2; on the basal bone side, the anterior was larger than the posterior but on the alveolar side, the anterior and posterior were the same (3 cases).3; on the basal bone side, the anterior and posterior were the same, but on the alveolar side, the anterior was larger than the posterior (2 cases).4; on the basal bone side, the anterior was larger than the posterior, but on alveolar side, the posterior was larger than the anterior (2 cases).5; on the basal and alveolar bone side, the anterior and posterior were the same (1 case).&lt;BR&gt;2) Except for two cases, satisfactory bone bridge formation was found.&lt;BR&gt;3) The mean age of bone grafting was 10 years and 3 months (range,7 to 15 years).&lt;BR&gt;4) Before bone grafting, the cleft side canine had, in 4 cases, already erupted, while in the other 10 cases it had not. Root formation of the cleft side canine ranged between 1/3 to complete.&lt;BR&gt;5) Two cases showed poor bone bridge formation on the basal bone side, and they were characterized by anterior bone defects that were larger than the posterior on the basal bone side, and widths of the basal bone defects that were larger than 20mm.&lt;BR&gt;In conclusion,&lt;BR&gt;1) Satisfactory bone bridge formation was gained at a high rate with two-stage palatoplasty combined with a Hotz plate.&lt;BR&gt;2) The width of a bone defect has strong influence on bone bridge formation.

    DOI: 10.11224/cleftpalate1976.26.1_114

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  • Application of Autotransplantation and Dental Implants to Bone-Grafted Sites in Patients with Cleft Lip and Palate

    IIDA Akihiko, ONO Kazuhiro, IMAI Nobuyuki, TAKAGI Ritsuo, HAMAMOTO Yoshioki, KOBAYASHI Tadaharu, ASAHITO Toshikazu, MOHRI Tamaki, TANAKA Mikako, SAKURAI Naoki, NOMURA Akiko

    J. Jpn. Cleft Palate Assoc.   26 ( 1 )   44 - 54   2001.4

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    It was well known that such anomalies as the number, form, and misdirection of eruption of the teeth adjacent to the alveolar cleft sometimes occur. It became common to adopt secondary alveolar bone grafting as a continuous treatment of cleft lip and palate. It was possible to recover the form and function by teeth movement to the bone grafted site, if such anomalies were little. It was difficult to reconstruct the alveolar cleft, if great anomalies, such as missing teeth, existed. It was considered that almost all severe cases were treated by prosthodontic treatment, previously. Damage to adjacent teeth has been unavoidable, in many cases. On the other hand, autotransplantation and dental implants have been developed in treatment of missing teeth. We have applied autotransplantation (5 cases), autotransplantation of cryopreserved teeth (2 cases), and dental implants (2 cases) to bone-grafted sites in patients with cleft lip and palate.&lt;BR&gt;All cases underwent secondary alveolar bone grafting from the iliac crest. The vertical width of grafted bone ranged from 8 to 16mm. All teeth in transplant or implant sites were upper lateral incisors that were congenitally missing or extracted by dwarf. The duration from bone grafting to plantation ranged from 4 to 50 months. Although some part of root absorption was observed in both cases of autotransplantation of cryopreserved teeth, all cases were successfully treated with final prosthodontic treatment.&lt;BR&gt;It was considered that autotransplantation and dental implants were very useful for the treatment of patients with alveolar cleft, and it was also considered that transplantation of cryopreserved teeth must be developed through clinical andbasic investigations.

    DOI: 10.11224/cleftpalate1976.26.1_44

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  • 正中唇裂の1例

    鳥養 葉子, 森田 修一, 朝日藤 寿一, 花田 晃治, 小野 和宏, 高木 律男

    甲北信越矯正歯科学会雑誌   8 ( 1 )   40 - 46   2000.12

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    9歳11ヵ月女児.生後1ヵ月時に正中唇裂,上唇小帯強直,口蓋部腫瘍の疑い,正中菱形舌炎の疑いがあった.1歳6ヵ月時に口唇形成術,上唇小帯伸展術,口蓋腫瘍摘出術,舌腫瘤biopsyを施行した.4歳6ヵ月時に矯正科での管理を開始した.8歳10ヵ月時に鼻中隔の形成不良,切歯管前方の上顎歯槽骨の離開,前鼻棘の劣形成などを認め,又,トルコ鞍の開大とその底部に骨欠損像,ならびに蝶形骨洞には脳瘤の存在が示唆された.脳神経外科での診査にてトルコ鞍底部が欠損しており,脳下垂体,視神経交叉,第III脳室が蝶形骨洞内に落ち込んでいる所見が得られた.脳脊髄液がトルコ鞍底部の骨欠損部より漏れている可能性が考えられた為,9歳6ヵ月時に脳神経外科にて蝶形骨の欠損部を腸骨の骨片と脂肪にて補填する手術を施行し現在経過は良好である

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  • 外側咽頭後リンパ節転移をきたした中咽頭癌に温熱化学放射線療法が奏効した1例

    星名 秀行, 井上 達夫, 鶴巻 浩, 小野 和宏, 長島 克弘, 宮浦 靖司, 高木 律男, 鈴木 誠

    新潟歯学会雑誌   30 ( 1 )   43 - 47   2000.9

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    65歳男,口峡咽頭部の痛みを主訴に当科を受診.MRIでは同部に腫瘍陰影,片側の外側咽頭後リンパ節(RLN)及び両側上内深頸リンパ節(SIJLN)に転移を認めた.病理組織学的に高分化型扁平上皮癌と診断され,UICC分類ではStage 4放射線療法と化学療法を併用し,2450MHzのマイクロ波空間放射型加温装置を用いた温熱療法を施行することとした.両側のSIJLNにおける腫瘍内温度は43℃以上約40分間維持された.温熱療法は8回(週2回)施行し,60Co照射後,CDDPと5FUの動注療法を併用した.治療後,腫瘍は著明に縮小し,MRIでは6ヵ月後に消失した.肺炎で死亡する迄の1年10ヵ月間,口峡咽頭や所属リンパ節に再発は認めなかった

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  • 高齢口腔癌患者に対するUFT 200mg投与時の血清中,腫瘍組織内5-FU濃度

    飯田 明彦, 高木 律男, 星名 秀行, 小野 和宏, 鍛冶 昌孝, 鶴巻 浩, 福田 純一, 長島 克弘, 宮浦 靖司, 早津 誠, 宮本 猛

    癌と化学療法   27 ( 10 )   1527 - 1532   2000.9

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    80歳以上の高齢口腔癌患者に対しUFTを1日200mgに減量して二分割投与した.1)血清中濃度は投与後1〜2時間でピークとなり,8時間後でも比較的高濃度が維持されていた.2)腫瘍組織内濃度は5検体中3検体で有効濃度の目安を超えていた.投与開始後の日数が増加するに従い,腫瘍組織内濃度も増加する傾向が認められた.3)副作用は造血器に軽度のものが認められたのみで肝機能,消化器系には出現しなかった

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  • 染色体異常を有する口唇・口蓋裂患者の病態ならびに治療について

    藤田 一, 小野 和宏, 永田 昌毅, 飯田 明彦, 今井 信行, 高木 律男, 大橋 靖

    日本口腔外科学会雑誌   46 ( 9 )   519 - 526   2000.9

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    口唇・口蓋裂患者のうち,染色体検査で核型異常が認められた12例を対象に,核型異常と病態との関係,病態に基づく治療法について検討を行い,口唇・口蓋裂と染色体異常の遺伝学的関連性について考察を行った.一次症例は10例,二次症例は2例であった.裂型は両側性唇顎口蓋裂4例,口蓋裂8例であった.染色体異常は全ての常染色体のみで,性染色体の異常は認めなかった.内臓奇形の合併8例,外表奇形,精神発達遅滞は全例に認められた.一次症例のうち8例にHotz床の装着を行い,6例に哺乳障害の改善を認めた.唇顎口蓋裂の1症例に口唇形成術を,口蓋裂の5症例に口蓋形成術を行った

    DOI: 10.5794/jjoms.46.519

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  • 二段階口蓋形成手術法を施行した片側性唇顎口蓋裂児の永久歯列弓形態 一段階法施行例及び健常児との比較

    小野 和宏, 飯田 明彦, 今井 信行, 福田 純一, 早津 誠, 高木 律男, 新井 透, 朝日藤 寿一, 石井 一裕, 森田 修一, 花田 晃治, 大橋 靖

    日本口蓋裂学会雑誌   25 ( 1 )   36 - 44   2000.1

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    Hotz床併用二段階口蓋形成手術法で治療した片側性唇顎口蓋裂児の歯齢III Cにおける永久歯列模型を分析し,一段階法施行例及び健常児と比べた結果,本治療法は顎発育抑制を軽減し,咬合の異常を避けうることが明らかになった

    DOI: 10.11224/cleftpalate1976.25.1_36

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  • Morphological Study on Maxillofacial Deformity in CL/Fr Strain Mouse : Especially in Anomaly of Maxillary Incisor Adjacent to Alveolar Cleft

    HAYATSU Makoto, NAGATA Masaki, KANNARI Yoji, ONO Kazuhiro, IIDA Akihiko, IMAI Nobuyuki, TAKAGI Ritsuo, OHASHI Yasushi

    日本口腔科学会雜誌   48 ( 6 )   454 - 463   1999.11

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    To clarify the mechanisms of the developmental anomaly of the tooth adjacent to the alveolar cleft, the maxillary incisor close to the cleft, the form of the alveolar cleft and the maxillofacial malformation combined with the cleft in CL/ Fr strain mouse with spontaneous cleft lip and/or alveolus (CL / A) were observed.<BR>Among 2340 offspring, a total of 515 mice (22.0%) with cleft lip and/or palate (CL/P) were observed. In this study, 11 mice with CL/P survived till weaning (3 weeks). The cleft patterns of survived mice were CL/A.<BR>In the dry skull observation, the alveolar clefts existed outside of the piriform apertura to the anterior part of the anterior palatine foramen. There were various types of cleft such as the wedge-shaped bone defect outside of the piriform apertura, the narrow cleft like bone suture, and the cleft separating the premaxilla into two parts.<BR>The side shift of the maxilla and/or premaxilla were observed in all cases. They tended to bend to the non-cleft side (6 out of 7 cases). Incisor anomalies on the cleft side were also observed, for example, tooth width reduction, rough enamel surface, and/or root shortening.<BR>As a result, the degree of tooth anomaly depended on the type of alveolar cleft.<BR>In conclusion, it was suggested that the developmental anomaly of maxillary incisor in CL/P mice was related to the cause of the cleft.

    DOI: 10.11277/stomatology1952.48.454

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  • A case of regional odontodysplasia in the left mandibular molar region

    KAJI Masataka, TAKAGI Ritsuo, SUZUKI Makoto, ONO Kazuhiro, NAGATA Masaki, OHASHI Yasushi

    Pediatric Oral and Maxillofacial Surgery   8 ( 2 )   8 - 11   1998.12

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    A case of regional odontodysplasia with osteomyelitis in the left mandilble was reported.<BR>A 3-year-old boy was referred to our clinic complaining of spontaneous pain of the left mandibular molar region.<BR>At first visit, severe swelling and redness were observed at the left buccal and submandibular region extraorally and from the lower left primary canine to retromolar region intraorally.<BR>The lower left primary second molar had not erupted completely. The enamel surface of this tooth was rough.<BR>The radiograph of the left mandible showed ghost-like appearances of the lower left primary canine and second molar. A radiolucent area was observed at the apical region of the lower left primary second molar. The germs of the lower left permanent canine and first molar were hypop-lastic and the germs of the lower left first and second premolar were not formed.<BR>The lower left primary second molar was extracted, after the inflammatory symptoms disappeared.<BR>Histological examination of the lower left primary first molar revealed that the enamel and dentin were thin, hypoplastic and hypocalcified. The dystrophic calcification was observed along the enamel surface.

    DOI: 10.11265/poms1991.8.2_8

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  • 最近14年間における外来患者の臨床統計的観察

    阿部 哲也, 飯田 明彦, 高木 律男, 星名 秀行, 小野 和宏, 鍛冶 昌孝, 今井 信行, 服部 幸男, 安島 久雄, 大橋 靖

    新潟歯学会雑誌   28 ( 2 )   9 - 17   1998.12

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    1)対象期間中における新来患者総数は,開設後10年に比べ大きな変化は認められなかった. 2)居住地別患者数をみると県外からの患者の割合が4.0%と増加していた. 3)紹介機関別頻度では,医学部附属病院を含む他の医療機関からの紹介患者の割合が前回調査を上回る40%台を維持した. 4)疾患別年平均患者数では顎関節疾患が121例(開設後10年:42例),顎変形症が38例(同:6例)と著明に増加しており,腫瘍も34例(同:24例)と増加を認めた.裂奇形は,49例と患者数に大きな変化はないものの,このうちで一次症例の占める割合は65%(同:37%)と高くなっていた

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  • 口唇裂口蓋裂発生に関与する母体環境の調査

    碓井 由紀子, 小野 和宏, 高木 律男, 鍛冶 昌孝, 永田 昌毅, 飯田 明彦, 今井 信行, 神成 庸二, 藤田 一, 早津 誠, 大橋 靖

    新潟歯学会雑誌   28 ( 2 )   1 - 8   1998.12

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    口唇裂又は口唇口蓋裂児の母親75名(口唇裂群),口蓋裂児の母親32名(口蓋裂群),及び,対照として1993年に出生した健常児の母親201名(以下,健常群)に作成した質問票を用いて,聞き取り方式で行い,それぞれの調査項目において各群を比較し検討した.その結果,口唇裂群では妊娠初期の感冒罹患の有無で健常群との間で有意差が認められ,口唇裂口蓋裂発生との関連が示唆された

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  • 新潟大学歯学部附属病院における口蓋裂診療班登録患者の動向及び評価

    寺田 員人, 大橋 靖, 八木 稔, 小林 正治, 中野 久, 野村 章子, 清水 光, 石井 一裕, 田口 洋, 小林 富貴子, 瀬尾 憲司, 磯野 信策, 小野 和宏, 高木 律男

    日本口蓋裂学会雑誌   23 ( 4 )   342 - 353   1998.10

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    1996年12月以前に生まれ,初回手術を当病院にて行った登録患者433名を対象とし,生年月,裂型,性別,現住所,各科における受診状況を集計した.対象患者は女207名,男226名であった.裂型は唇裂が26名,唇顎裂が70名,唇顎口蓋裂が199名,口蓋裂が138名であった.県内外から広く受診しており,特に県内で発生した口唇裂口蓋裂を有する人の殆どが受診していた.各科が管理している対象患者数は,各々口腔外科371名,言語治療室166名,予防歯科127名,小児歯科163名,矯正科174名,保存科2名,補綴科1名であった

    DOI: 10.11224/cleftpalate1976.23.4_342

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  • Hard palate closure in two-stage palatoplasty

    IIDA Akihiko, OHASHI Yasushi, TAKAGI Ritsuo, ONO Kazuhiro, IMAI Nobuyuki, KANNARI Yoji, HAYATSU Makoto

    J.Jpn.Cleft Palate Assoc.   23 ( 2 )   68 - 74   1998.4

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    The intraoperative and postoperative results of hard palate closure were investigated in the case of two-stage palatoplasty in our clinic. Comparative analyses have been made between the results of the cases operated only by using vomer flap (vomer flap group, n=76)and those of the cases operated by using vomer and palatal flaps (vomer+palatal flap group, n=16).&lt;BR&gt;The results were as follows:&lt;BR&gt;1. The blood loss of the vomer flap group (mean: 42.4 g) is significantly less than that of the vomer+palatal flap group (mean: 103.6 g).&lt;BR&gt;2. Only 10 cases (10.9 %) had postoperative fistula. The ratio of fistula formation was not significantly different between the two groups. There was no case with large fistula that causes critical dysfunction such as speech difficulties.&lt;BR&gt;3. Raw surface made by operation have been covered by TERUDERMIS(Artificial dermis made of atelocollagen). There was no case with severe operation scar.&lt;BR&gt;4. It was considered that the usefulness of two-stage palatoplasty can be enhanced by the operation using vomer flap alone, which causes less surgical damage.

    DOI: 10.11224/cleftpalate1976.23.2_68

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  • ヒト下顎位置感覚への顎関節受容器及び咀嚼筋受容器の関与

    小野 和宏, 高木 律男, 小林 龍彰

    日本口腔科学会雑誌   47 ( 2 )   199 - 205   1998.4

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    顎関節からの感覚信号は下顎位置感覚には寄与せず,閉口筋内の筋紡錘からの筋感覚信号が大きく関与していることが示唆された

    DOI: 10.11277/stomatology1952.47.199

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  • Team Approach in a Clinical Case of Cleft Lip and Palate Complicated with Partial Anodontia

    NOMURA Akiko, ONO Kazuhiro, KANAI Kanehide, KOHNO Shoji, OHASHI Yasushi, HANADA Kooji, TERADA Kazuto, SAKURAI Naoki, TANAKA Mikako

    J.Jpn.Cleft Palate Assoc.   23 ( 1 )   1 - 12   1998

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    An 18 year-old female visited our clinic with aesthetic complaints due to cleft lip and palate on the right side complicated with partial anodontia. Clinical and cephalometric examinations revealed severe orofacial deformities such as undergrowth of the maxilla and overclosure of the mandible. The purpose of the treatment was aesthetic improvement, however, it was determined that orthognathic surgery alone could not provide a satisfactory prognosis.&lt;BR&gt;In order to determine the optimal mandibular position, occlusal plane, and aesthetics prior to orthognathic surgery, a diagnostic upper denture was made. The newly-established intermaxillary relationships were evaluated clinically, cephalometrically, and electromyographically.. Aesthetic improvement was obtained by the team approach and the goal of orthognathic surgery became more predictable by the prosthetic approach.

    DOI: 10.11224/cleftpalate1976.23.1_1

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  • Incidence of Cleft Lip and/or Palate in Niigata Prefecture

    ONO Kazuhiro, OHASHI Yasushi, TAKAGI Ritsuo, NAGATA Masaki, IIDA Akihiko, IMAI Nobuyuki, KANNARI Yoji, HAYATSU Makoto

    J.Jpn.Cleft Palate Assoc.   22 ( 3 )   138 - 143   1997.7

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    Cleft lip and/or palate is a malformation of relatively high incidence in Japan. Many studies have reported its incidence, however, there were little of recent surveys based on a large size of population. Since it is expected to have some changes of social environmental factors such as maternal aging, present study is aimed to investigate current rate of incidence using a questionnaire at the maternity hospitals in Niigata Prefecture from November,1994 to October,1995.&lt;BR&gt;A total of 20566 new born infants were examined, and 36 had cleft lip and /or palate (0.175 %). Among those 36 infants with cleft lip and/or palate,13 had cleft lip,15 had cleft lip and palate, and 8 had cleft palate. Of the 13 infants with cleft lip,11 were unilateral and 2 were bilateral type of cleft. Of the 15 infants with cleft lip and palate,11 were unilateral and 4 were bilateral.&lt;BR&gt;As for the sex,6 males and 7 females were in infants with cleft lip,10 males an d 5 females in infants with cleft lip and palate, and 1 male and 7 females in infants with cleft palate only.&lt;BR&gt;Association of malformations were recognized in 9 out of the 36 infants (25.0 %) includi ng syndromes of Pierre-Robin, Opitz, Down,18 trisomy, and defects of the brain, skull, heart, limbs, and auricle.

    DOI: 10.11224/cleftpalate1976.22.3_138

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  • A case of mucoepidermoid carcinoma of the lower lip

    NOZAWA Kayoko, TAKAGI Ritsuo, ONO Kazuhiro, OHASHI Yasushi, IRIE Tarou, MUNAKATA Ryuichi

    Jpn. J. Oral Maxillofac. Surg.   43 ( 4 )   355 - 357   1997.4

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    We report a rare case of mucoepidermoid carcinoma arising from a minor salivary gland in the lower lip. Mucoepidermoid carcinoma is a salivary gland neoplasm that is characterized by varying combinations of mucous, epidermoid, and intermediate cells. As for the minor salivary glands, the palate is the most common site for the development of this tumor. A 60-year-old woman presented at our clinic on February 8, 1994 because of a mass in the lower lip. There was a well-circumscribed swelling, measuring 18mm in diameter, in the lower lip. It was elastic soft and movable on palpation. Histopathological diagnosis of a mucoepidermoid carcinoma was made on examination of a biopsy specimen. With the patient under general anesthesia, the tumor was excised with a 5-mm safety margin on March 3, 1994. Histopathological examination of the surgical specimen showed a well-differentiated mucoepidermoid carcinoma. After surgery, the patient had a fairly good prognosis with no evidence of local recurrence or distant metastasis.

    DOI: 10.5794/jjoms.43.355

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  • Spontaneous Narrowing of Residual Hard Palate Cleft after Velar Closure in Two-Stage Palatoplasty

    ONO Kazuhiro, OHASHI Yasushi, TAKAGI Ritsuo, NAGATA Masaki, IIDA Akihiko, IMAI Nobuyuki, KANNARI Yoji, HAYATSU Makoto

    J.Jpn.Cleft Palate Assoc.   21 ( 3 )   126 - 141   1996.7

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    In patients who undergo two-stage palatoplasty of cleft lip and palate, the residual hard palate cleft gradually narrows after velar closure. Depending on the type, the cleft borders may come close together or remain slightly apart. In this study, the residual hard palate cleft after veloplasty, performed according to the modified Widmaier technique described by Perko, was examined for changes by using serial maxillary casts obtained from 53 patients one year and six months to six years of age. The results were as follows:&lt;BR&gt;1. The residual cleft spontaneously narrowed until four years of age and showed no statistically significant changes there after.&lt;BR&gt;2. The anterior cleft width was reduced to 15% and 55% of that at the velar closure in unilateral and bilateral cleft alveolus and palate, respectively. On the other hand, the posterior cleft width was reduced to 50% in both cleft types.&lt;BR&gt;3. In two patients with unil ateral cleft alveolus and palate, the cleft borders came into contact and apparently disappeared.&lt;BR&gt;4. As the maxillary alveolar width was not reduced, the narrowing of the hard palate cleft was thought to be due to growth of the palatal shelves in the medial direction.&lt;BR&gt;5. A difference in attachment of the nasal septum to the maxil lary segments had no influence on the narrowing of the hard palate cleft.

    DOI: 10.11224/cleftpalate1976.21.3_126

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  • Cleft palate repair by Furlow double opposing Z-plasty : I. Intraoperative and postoperative results

    ONO Kazuhiro, OHASHI Yasushi, KANNARI Yoji

    Jpn. J. Oral Maxillofac. Surg.   41 ( 3 )   214 - 219   1995.3

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    Cleft palate repair using Furlow double opposing Z-plasty was performed in 31 patients between 1990 and 1994. To determine the advantages and disadvantages of this technique, Furlow palatoplasty was compared with the pushback procedure. Twenty-seven patients undergoing palatal closure with the pushback technique, performed by the same surgeon during the same period, served as controls. Nineteen of the 31 patients in the Furlow group had cleft palate, nine had submucosal cleft palate, and three had cleft lip and palate. Mean age at Furlow palatoplasty was 2.4 years. In the pushback group, 17 of the 27 patients had cleft palate, three had submucosal cleft palate, and seven had cleft lip and palate. Mean age at pushback palatoplasty was 2.1 years. Operating time and blood loss in the Furlow group were 83.9&amp;plusmn;14.9 minutes and 28.3&amp;plusmn;28.8ml, respectively, while the corresponding values in the pushback group were 66.3&amp;plusmn;17.2 minutes and 39.9&amp;plusmn;38.5ml. Although operating time in the Furlow group was longer than in the pushback group, blood loss was significantly less. Intraoperative results were favorable, with acceptable operating time and blood loss. No postoperative complications occurred in the Furlow group, and adequate oral intake was achieved immediately after palatoplasty. The maximum body temperature and duration of postoperative fever in the Furlow group were 37.8&amp;plusmn;0.4&amp;deg;C and 37.0&amp;plusmn;21.0 hours, respectively, while the corresponding values in the pushback group were 38.3&amp;plusmn;0.5&amp;deg;C and 76.1&amp;plusmn;29.7 hours. The rise in body temperature in the Furlow group was significantly lower, and the postoperative course was satisfactory. Oronasal fistulas did not develop.

    DOI: 10.5794/jjoms.41.214

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  • Cleft palate repair by Furlow double opposing Z-plasty : II. Speech results and effects on maxillary growth

    ONO Kazuhiro, OHASHI Yasushi, KANNARI Yoji, ISONO Shinsaku

    Jpn. J. Oral Maxillofac. Surg.   41 ( 3 )   220 - 223   1995.3

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    Cleft palate repair by Furlow double opposing Z-plasty was performed in 31 patients between 1990 and 1994. Speech results and effects on maxillary growth following Furlow palatoplasty were investigated and compared with the pushback procedure. Twentyseven patients undergoing pushback palatoplasty, performed by the same surgeon during the same period, served as controls.&lt;BR&gt;1. Twenty-two patients in the Furlow group and 15 patients in the pushback group were old enough to permit speech evaluation. Mean ages at palatoplasty in the Furlow group and the pushback group were 2.4 years and 2.1 years, respectively. There were no differences between the groups in the distribution of type of cleft or age at palatoplasty. Mean ages at speech evaluation in the Furlow group and the pushback group were 4.1 years and 4.5 years, respectively. Twenty of the 22 patients in the Furlow group had no evidence of velopharyngeal insufficiency, while one had mild and the other moderate to severe insufficiency. Twelve of the 15 patients in the pushback group had no evidence of velopharyngeal insufficiency, while one had mild and two had moderate to severe insufficiency. No significant difference was found between the two groups, and the early speech results were encouraging.&lt;BR&gt;2. Effects on maxillary growth following cleft palate repair were evaluated by the presence or absence of crossbite in 18 patients in the Furlow group and nine patients in the pushback group who had completed deciduous dental eruption. Mean ages at palatoplasty in the Furlow group and the pushback group were 2.6 years and 2.0 years, respectively. There were no differences between the groups in the distribution of type of cleft or age at palatoplasty. Mean ages at growth evaluation were 4.2 years in the two groups. Only five patients in the Furlow group had anterior crossbite. In the pushback group, on the other hand, three patients had anterior crossbite, one had posterior crossbite, and three had both anterior and posterior crossbite. The difference between the presence of crossbite in the two groups was statistically significant. Furlow palatoplasty allowed adequate maxillary growth.

    DOI: 10.5794/jjoms.41.220

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  • Effects of the early maxillary orthopaedic appliance for cleft lip and palate Reviewed

    K Ono, A Iida, Y Ohashi, K Shimada

    BRAIN AND ORAL FUNCTIONS   1079   265 - 272   1995

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  • 舌痛症の臨床統計的検討

    小野 和宏, 大橋 靖, 高木 律男

    新潟歯学会雑誌   24 ( 1 )   13 - 20   1994.6

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    過去18年5ヵ月間に当科を受診した舌痛症患者159例の病態像について臨床統計的に検討した。中年以降の女性が対象症例のほとんどを占めていた。性格的には心気傾向を示し,癌の恐怖を強く訴えるものが61例みられた。発症時期に一致して対象症例の1/4が歯科治療を受けていた。舌の痛みは歯や補綴物と接触し易い舌尖や舌側縁に生じる場合が多く,22例では微弱な発赤が観察された。以上のことから,舌痛症の痛みの一因として,歯や補綴物による慢性的な機械的刺激の関与が考えられた

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  • Vasomotor Reflex Induced by Periodontal Stimulation in Palatal Mucosaof Rat

    Kazuhiro ONO, Yasushi OHASHI, Chie YAMAMURA

    Niigata dental journal   23 ( 2 )   25 - 36   1993.12

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    Effects of electrical stimulation of periodontium and noxious, non-noxious mechanical stimulation of tooth on palatal blood flow were studied by using a laser Doppler flowmeter in anaesthetized rats. The findings obtained were as follows: 1. Electrical stimulation of periodontium produced an increase in the blood flow at thin vessels of palatal mucosa. Afferent groups which induced the flow increase response were Aδ and C fibers. 2. Mechanical stimulation of tooth produced an increase in the blood flow at thin vessels. Noxious stimulation induced a marked flow increase. Non-noxious stimulation also induced a less marked but constant increase in the blood flow. 3. At arteria palatine which spread thin vessel branches, electrical stimulation of periodontium and mechanical stimulation of tooth induced a decrease in the blood flow. 4. Both flow increase and decrease responses were inhibited following the resection of bilateral ganglion cervical superius or the intravenous injection of α – blocker.歯根膜の感覚受容器から口腔の循環系への反射について明らかにするために、浅く麻酔したラットを用い、歯根膜への電気刺激および侵害性、非侵害性の機械的刺激が口蓋の血流に及ぼす影響をレーザードプラー血流計を使用し観察した。血流測定部位は横口蓋ヒダ粘膜(口蓋粘膜部)、および第一臼歯相当部口蓋動脈上(口蓋動脈部)とした。 得られた結果は以下の通りである。 1. 口蓋粘膜部では、歯根膜の電気刺激により血流増加反応が観察された。この反応を起こす求心性線維は、AδおよびC線維群であった。 2. 電気刺激時と同様に、歯の機械的刺激により口蓋粘膜部では血流増加反応が引き起こされた。血流増加は400g以下の非侵害刺激強度から観察され始め、侵害刺激により著明な反応が認められた。 3. 口蓋動脈部では、歯根膜の電気刺激ならびに歯への機械的刺激により血流減少反応が観察された。 4. 歯根膜刺激による口蓋の血流変化は、上頸神経節切除やアルファ遮断剤の静脈内投与により著明に抑制された。

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  • PATTERNS OF JAW REFLEXES INDUCED BY INCISAL AND MOLAR PRESSURE STIMULATION IN RELATION TO BACKGROUND LEVELS OF JAW-CLENCHING FORCE IN HUMANS

    C YAMAMURA, S KOSUGI, K ONO, K SHIMADA

    JAPANESE JOURNAL OF PHYSIOLOGY   43 ( 1 )   87 - 102   1993

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    Patterns of jaw reflexes induced by periodontal stimulation were examined in ten adults. Surface electromyograms (EMGs) from the masseter and anterior temporal muscles were recorded when pressure stimulation was applied to either an incisor or a molar. Reflex responses to periodontal pressure stimulation varied, depending on the background levels of jaw-clenching force that preceded stimulation (background clenching force, BCF). At low BCF, excitatory reflexes were elicited from the jaw-closing muscles and jaw-clenching force. However, the magnitude of excitatory reflexes varied with the location of the stimulated tooth along the dentition. While excitatory reflexes were induced equally in the masseter and temporal muscles during incisal stimulation, stronger excitatory reflexes were induced in the temporal muscle than in the masseter muscle during molar stimulation. At high BCF, inhibitory reflexes in the jaw-closing muscles and jaw-clenching force were elicited in eight subjects (group A) during periodontal stimulation. However, excitatory reflexes in the muscles and force were elicited in the remaining two subjects (group B). In the subjects of group A, stronger inhibitory reflexes were elicited in the temporal muscle than in the masseter muscle, and jaw-clenching force also decreased during both incisal and molar stimulation. In the subjects of group B, the magnitude of excitatory reflexes decreased with increases in BCF.

    DOI: 10.2170/jjphysiol.43.87

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  • Clinicostatistical Observation of Cleft Lip and Palate with Other Congenital Anomalies

    ONO Kazuhiro, OHASHI Yasushi, NAKANO Hisashi, IIDA Akihiko, KANNARI Yoji, ISONO Shinsaku

    J.Jpn.Cleft Palate Assoc.   17,340-355 ( 4 )   340 - 355   1992.10

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    In order to seek better management and treatment of cleft lip and palate with other congenital anomalies, specially serious ones, we retrospectively investigated clinical findings and our managements of primary cases with complicated anomalies who visited the second Department of Oral and Maxillo-facial Surgery, Niigata University Dental Hospital during a recent 6 year period from Jan.1985 to Feb.1991.&lt;BR&gt;The findings obtained were as follows:&lt;BR&gt;1. Fifty four of 208 cases of cleft lip and/or palate (26.0 %) had other congenital anomalies. The incidence of complicating anomalies was highest in patients with cleft palate (50.9 %), followed by patients with submucosal cleft palate (20.0 %), cleft lip, alveolus and palate (17.2 %), cleft lip and alvelous (11.8 %), and cleft lip (9.1 %). Fifty percent of 54 cases were associated with more than two kinds of other anomalies.&lt;BR&gt;2. The anomalies frequently associated were micrognathia (10.6 %), extremity deformity (7.2 %), and congenital heart disease (7.2 %).&lt;BR&gt;3. Pierre-Robin syndrome (19 cases), van der Woude syndrome (2 cases), cerebro-costo-mandibular syndrome (1 case), Apert syndrome (1 case), asplenia syndrome (1 case), Beckwith-Wiedemann syndrome (1 case), Cornelia de Lange syndrome (1 case), Larsen syndrome (1 case), and clefting/ankyloblepharon syndrome (1 case) were found. Chromosomal aberration was confirmed in 4 cases.&lt;BR&gt;4. Most of the serious cases had multiple anomalies as patients with chromosomal aberration and syndrome, and were associated frequently with cranial deformity, eye deformity, micrognathia, extremity deformity, and congenital heart disease. Two of 4 cases with chromosomal abberation died in infancy. Mental development was delayed in all 9 cases with cranial deformity.&lt;BR&gt;5. Feeding difficulty and dyspnea of Pierre-Robin syndrome were improved by using Hotz type orthopaedic appliance (Hots plate).&lt;BR&gt;6. Plastic surgery of cleft lip and palate was done in 11 of 15 cases with congenital heart disease. There was no fatality case. It is thought to be important that surgery be done with an untraumatic method in close cooperation with pediatricians and anesthetists.&lt;BR&gt;7. In patients with mental retardation, palatoplasty was carried out usually irrespective of mental and speech developments. If the physical condition is not stable, palatal repair should be delayed according to mental development.

    DOI: 10.11224/cleftpalate1976.17.4_340

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  • Castillo-Morales口蓋床(C-M床)によるDown症候群の口腔機能障害の改善

    小野 和宏, 大橋 靖, 中野 久

    日本口腔科学会雑誌   41 ( 1 )   197 - 206   1992.1

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    6名のDown症児にCastillo-Morales口蓋床を用いて口腔機能障害の治療を行った.C-M床は生後可及的早期に装着することによりDown症候群の舌突出を矯正し,口腔周囲筋の活動を賦活させることができ,口腔機能の改善に有用であることが明らかになった.また,口腔機能の改善が顎顔面の成長によい影響を与えていることが示唆された.一方で,その形態には基礎的研究を踏まえて,さらに改良の余地があるものと思われた

    DOI: 10.11277/stomatology1952.41.197

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  • ヒト歯および歯肉への機械的刺激による歯肉の反射性血流増加について

    小野 和宏

    日本口腔科学会雑誌   39 ( 2 )   389 - 404   1990.4

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    歯および歯肉への非疼痛性および疼痛性の機械的刺激が歯肉血流に及ぼす影響を,レーザードプラー血流計を使用し10名の健康な被験者で観察した.咀嚼などの口腔機能時に歯や歯肉に加わる日常的な機械的刺激により,歯肉の血流は増加した

    DOI: 10.11277/stomatology1952.39.389

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    Other Link: http://search.jamas.or.jp/link/ui/1991122630

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  • 歯科衛生士講座 口腔外科学 第2版

    古森孝英, 石川誠, 梅田正博, 小野和宏, 鎌田伸之, 北川善政, 草間幹夫, 重石英生, 渋谷恭之, 嶋田昌彦, 杉山勝, 杉山芳樹, 武知正晃, 深山治久, 古土井春吾, 升井一朗, 山崎裕, 横尾聡, 吉増秀實, 依田哲也, 古森孝英( Role: Joint author)

    永末書店  2017.1  ( ISBN:4816013180

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  • ディープ・アクティブラーニング : 大学授業を深化させるために

    松下 佳代, 溝上 慎一, 森 朋子, Barkley Elizabeth F, Marton Ference, 安永 悟, Mazur Eric, 田口 真奈, 関田 一彦, 三津村 正和, 小野 和宏, 日向野 幹也, 京都大学高等教育研究開発推進センター

    勁草書房  2015  ( ISBN:9784326251018

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  • 歯科衛生士講座 歯科衛生士のための口腔外科学

    古森孝英, 石川 誠, 依田哲也, 梅田正博, 小野和宏, 鎌田伸之, 北川善政, 草間幹夫, 渋谷恭之, 嶋田昌彦, 杉山 勝, 杉山芳樹, 野谷健一, 深山治久, 古土井春吾, 升井一朗, 山崎 裕, 横尾 聡, 吉増秀實, 古森孝英( Role: Joint author)

    永末書店  2011.10  ( ISBN:4816012338

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  • 母体環境要因と本症発生(共著)

    口唇口蓋裂の疫学的研究.東山書房  1998 

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  • Muscle activity changes of soft palate in cleft lip and palate patients(共著)

    Transactions 8th International Corgress on Cleft Palate and Related Craniofacial Anomalies. Stamford Press  1997 

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  • Application of the Furlow method to primary velar closure in two-stage palatoplasty

    Transactions 8th International Congress on Cleft Palate and Related Croniofacial Anomalies. Stom ford Press  1997 

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  • Effects of the early maxillary orthopaedic appliance for cleft lip and palate.

    Brain and oral functions. Oral motor function and dys function. Elsevier  1995 

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  • The relationship between preoperative posterior cleft width and postoperative primary occlusion

    大湊麗, 大湊麗, 大湊麗, 小野和宏, 小野和宏, 児玉泰光, 結城龍太郎, 永井孝宏, 小林亮太, 市川佳弥, 丹原惇, 佐藤真由美, 濃野要, 飯田明彦, 若槻華子, 宮田昌幸, 小林正治, 齋藤功, 高木律男, 冨原圭

    日本口蓋裂学会雑誌   48 ( 2 )   2023

  • The Effectiveness of Class Design for Academic Writing Using the Argumentation Model

    42 ( 1 )   125 - 134   2020.5

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  • 新潟大学歯学部における診療参加型臨床実習と歯科医師臨床研修の年間診療数に対する実態調査

    塩見 晶, 石崎 裕子, 伊藤 晴江, 奥村 暢旦, 長谷川 真奈, 藤井 規孝, 小林 正治, 小野 和宏, 前田 健康

    日本歯科医学教育学会雑誌   34 ( 3 )   92 - 99   2018.12

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    現在、歯科大学や大学歯学部ではそれぞれにおいて診療参加型臨床実習の改善・充実が図られている。診療参加が学生に大きな教育効果をもたらすことには疑いの余地はなく、歯科医師臨床研修にも同様のことが当てはまる。一方、診療参加型臨床実習・臨床研修を運営するためには、これらの制度に理解を示し、協力を得られる患者を確保することが必要不可欠である。そこで、新潟大学の診療参加型臨床実習および単独型プログラム歯科医師臨床研修の現状を把握するとともに、さらなる改善や発展に寄与するための資料を得ることを目的として、新潟大学医歯学総合病院歯科における過去5年間の患者データと臨床実習・単独型プログラム臨床研修の内容を調査した。調査期間中のおおよその平均は学生43名、研修歯科医24名で、それぞれの一人当たり年間診療患者数は125名、279名であった。新患担当数も学生より研修歯科医のほうが多く、歯科医師臨床研修に対しては患者の理解を得やすいことが示された。しかし、臨床実習・臨床研修のプログラムから算出した診療従事可能日数と患者数を比較すると、いずれの患者数も妥当性が高く、現状を最低限として維持すべきことが示された。また、決して長くはない臨床実習・臨床研修を効率的に運営するためには、連続性を考慮しながら連携して体制整備に努める必要があると考えられた。(著者抄録)

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  • 歯科臨床実習におけるポートフォリオによる形成的評価と総括的評価の関連について

    小田陽平, 小野和宏, 藤井規孝, 小林正治, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   37th   87   2018.7

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  • 舌縮小術を行った口蓋裂を伴うBeckwith-Wiedemann症候群の1例

    児玉 泰光, 大湊 麗, 永井 孝宏, 渡部 桃子, 山田 茜, 結城 龍太郎, Salazar Andrea Rei, 市川 佳弥, 丹原 惇, 齋藤 功, 小野 和宏, 高木 律男, 新潟大学医歯学総合病院口唇口蓋裂診療チーム

    日本口蓋裂学会雑誌   43 ( 2 )   141 - 141   2018.4

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  • 二段階口蓋形成手術法における構音発達過程の検討

    大湊 麗, 小野 和宏, 児玉 泰光, 結城 龍太郎, 山田 茜, Estacio Salazar, Andrea Rei, 永井 孝宏, 渡部 桃子, 小山 貴寛, 飯田 明彦, 永田 昌毅, 高木 律男

    日本口蓋裂学会雑誌   43 ( 2 )   161 - 161   2018.4

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  • 機能性構音障害の臨床統計的検討

    大湊 麗, 児玉 泰光, 小山 貴寛, 池田 順行, 小野 和宏, 永田 昌毅, 高木 律男

    小児口腔外科   27 ( 2 )   97 - 97   2017.10

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  • 連携機能を活用した歯学教育高度化プログラム

    竹石龍右, 加来咲子, 天雲太一, 冨士岳志, 三村純代, 首藤崇裕, 石田陽子, 秋葉奈美, 魚島勝美, 小野和宏, 高橋信博, 二川浩樹, 加藤功一, 佐々木啓一, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   36th   125   2017.7

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  • 歯科臨床研修ポートフォリオシステムにおける動画の活用と学習の「見える化」

    小田陽平, 小野和宏, 藤井規孝, 小林正治, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   36th   100   2017.7

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  • 標準化された病態顎模型を用いた客観的歯科臨床技能評価方法の開発―第4報―

    秋葉奈美, 天雲太一, 冨士岳志, 首藤崇裕, 小野和宏, 吉羽邦彦, 二川浩樹, 津賀一弘, 田地豪, 加藤功一, 佐々木啓一, 魚島勝美, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   36th   118   2017.7

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  • 標準化された病態顎模型を用いた客観的歯科臨床技能評価方法の開発(第4報)

    秋葉 奈美, 天雲 太一, 冨士 岳志, 首藤 崇裕, 小野 和宏, 吉羽 邦彦, 二川 浩樹, 津賀 一弘, 田地 豪, 加藤 功一, 佐々木 啓一, 魚島 勝美, 前田 健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   36回   118 - 118   2017.7

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  • 連携機能を活用した歯学教育高度化プログラム

    竹石 龍右, 加来 咲子, 天雲 太一, 冨士 岳志, 三村 純代, 首藤 崇裕, 石田 陽子, 秋葉 奈美, 魚島 勝美, 小野 和宏, 高橋 信博, 二川 浩樹, 加藤 功一, 佐々木 啓一, 前田 健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   36回   125 - 125   2017.7

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  • 顎矯正手術を行ったビスフォスフォネート製剤を内服する顎変形症の1例

    池田 順行, 小野 和宏, 阿部 裕子, 丹原 惇, 新島 綾子, 小玉 直樹, 高木 律男

    日本顎変形症学会雑誌   27 ( 2 )   118 - 118   2017.5

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  • 二段階口蓋形成術施行片側性唇顎口蓋裂児におけるHuddart/Bodenham Indexを用いた咬合評価

    児玉 泰光, 丹原 惇, 市川 佳弥, 大湊 麗, 深井 真澄, 渡部 桃子, 永井 孝宏, 小山 貴寛, 永田 昌毅, 飯田 明彦, 小野 和宏, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   42 ( 2 )   166 - 166   2017.4

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  • 二段階口蓋形成手術法における硬口蓋閉鎖時期の検討 ナゾメーターによる分析

    大湊 麗, 小野 和宏, 飯田 明彦, 児玉 泰光, 小山 貴寛, 永田 昌毅, 高木 律男

    日本口蓋裂学会雑誌   42 ( 2 )   131 - 131   2017.4

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  • 口蓋裂患者における口蓋裂言語の心理的受容過程

    深井真澄, 深井真澄, 大湊麗, 大湊麗, 児玉泰光, 永田昌毅, 今井信行, 小野和宏, 小林正治, 高木律男, 高木律男

    新潟歯学会雑誌   46 ( 2 )   110   2016.12

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  • 二段階口蓋形成手術法における硬口蓋閉鎖時期の検討 言語機能による分析

    大湊 麗, 小野 和宏, 児玉 泰光, 小山 貴寛, 五十嵐 友樹, 小林 孝憲, 飯田 明彦, 永田 昌毅, 高木 律男

    新潟歯学会雑誌   46 ( 2 )   110 - 111   2016.12

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  • 連携機能を活用した歯学教育高度化プログラム―平成26~27年度の実績―

    竹石龍右, 加来咲子, 天雲太一, 竹内裕尚, 三村純代, 首藤崇裕, 石田陽子, 秋葉奈美, 魚島勝美, 小野和宏, 高橋信博, 二川浩樹, 佐々木啓一, 菅井基行, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   35th   99   2016.7

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  • 診療参加型歯科臨床実習におけるweb公開型eポートフォリオ―第3報 記述内容の質的分析の試み―

    小田陽平, 小野和宏, 藤井規孝, 小林正治, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   35th   88   2016.7

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  • 大学間連携機能を利用した相互乗り入れ講義の取り組み

    加来咲子, 石田陽子, 竹石龍右, 天雲太一, 竹内裕尚, 三村純代, 首藤崇裕, 小野和宏, 佐々木啓一, 菅井基行, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   35th   100   2016.7

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  • 疾患統合模型を用いた卒業時歯科臨床技能評価方法の開発

    秋葉奈美, 小野和宏, 吉羽邦彦, 加来咲子, 竹石龍右, 魚島勝美, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   35th   135   2016.7

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  • 標準化された病態顎模型を用いた客観的歯科臨床技能評価方法の開発―第3報―

    田地豪, 天雲太一, 竹内裕尚, 秋葉奈美, 三村純代, 首藤崇裕, 二川浩樹, 津賀一弘, 小野和宏, 吉羽邦彦, 魚島勝美, 前田健康, 佐々木啓一, 菅井基行

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   35th   82   2016.7

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  • 診療参加型歯科臨床実習におけるweb公開型eポートフォリオ―第2報 運用実績とシステム改善について―

    小田陽平, 石川裕子, 小野和宏, 藤井規孝, 小林正治, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   34th   78   2015.7

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  • 標準化された病態顎模型を用いた客観的歯科臨床技能評価方法の開発―第2報―

    魚島勝美, 天雲太一, 竹内裕尚, 小野和宏, 吉羽邦彦, 秋葉奈美, 二川浩樹, 津賀一弘, 田地豪, 首藤崇裕, 三村純代, 三村純代, 菅井基行, 佐々木啓一, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   34th   81   2015.7

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  • 総合模型実習におけるルーブリックを用いた評価とその信頼性検討

    秋葉奈美, 長澤麻沙子, 小野和宏, 秋葉陽介, 前田健康, 魚島勝美

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   34th   84   2015.7

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  • 二段階口蓋形成法においてFurlow法を施行した口蓋裂児の顎発育 Perko法との比較

    眞舘 幸平, 高木 律男, 大湊 麗, 児玉 泰光, 飯田 明彦, 小野 和宏, 朝日藤 寿一, 齋藤 功

    新潟歯学会雑誌   45 ( 1 )   27 - 27   2015.6

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  • 口蓋裂言語が長期化している口蓋裂成人患者の心情に関する質的研究

    深井 真澄, 大湊 麗, 工藤 和子, 児玉 泰光, 永田 昌毅, 今井 信行, 小野 和宏, 齋藤 功, 小林 正治, 高木 律男

    日本口蓋裂学会雑誌   40 ( 2 )   156 - 156   2015.4

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  • 診療参加型歯科臨床実習におけるweb公開型eポートフォリオの開発と運用

    小田陽平, 石川裕子, 小野和宏, 藤井規孝, 小林正治, 前田健康

    新潟歯学会雑誌   44 ( 2 )   124 - 125   2014.12

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  • 腸骨移植後顎裂部への歯の移植 凍結保存歯移植の可能性

    小山 貴寛, 芳澤 享子, 児玉 泰光, 小林 孝憲, 安島 久雄, 五十嵐 友樹, 小野 和宏, 齋藤 功, 小林 正治, 飯田 明彦, 高木 律男

    日本口蓋裂学会雑誌   39 ( 2 )   99 - 99   2014.4

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  • 口唇裂・口蓋裂の治療評価に関するアンケート調査

    朝日藤 寿一, 藤原 百合, 鈴木 茂彦, 吉村 陽子, 後藤 昌昭, 小野 和宏, 須佐美 隆史, 槙 宏太郎, 峪 道代, 鈴木 恵子, 齋藤 功, 一般社団法人日本口蓋裂学会Japancleft委員会

    日本口蓋裂学会雑誌   39 ( 2 )   183 - 183   2014.4

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  • 口唇裂・口蓋裂の治療評価に関するアンケート調査 音声言語領域について

    藤原 百合, 朝日藤 寿一, 峪 道代, 鈴木 恵子, 鈴木 茂彦, 吉村 陽子, 後藤 昌昭, 小野 和宏, 須佐美 隆史, 槇 宏太郎, 齋藤 功, 一般社団法人日本口蓋裂学会Japancleft委員会

    日本口蓋裂学会雑誌   39 ( 2 )   151 - 151   2014.4

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  • PBLにおける改良版トリプルジャンプの試み

    小野和宏, 山村健介, 石川裕子, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   33rd   81   2014

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  • 標準化された病態顎模型を用いた客観的歯科臨床技能評価方法の開発

    天雲太一, 竹内裕尚, 島内英俊, 小野和宏, 吉羽邦彦, 藤井規孝, 石田陽子, 二川浩樹, 津賀一弘, 田地豪, 菅井基行, 佐々木啓一, 前田健康, 魚島勝美

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   33rd   71   2014

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  • 診療参加型歯科臨床実習におけるweb公開型eポートフォリオの開発と運用

    小田陽平, 石川裕子, 小野和宏, 藤井規孝, 小林正治, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   33rd   76   2014

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  • 口唇口蓋裂患者における顎矯正手術に関連した下顎枝の形態学的特徴 軸位断CTを用いた下顎孔レベルの計測

    児玉 泰光, 田中 礼, 永田 昌毅, 小山 貴寛, 小林 孝憲, 五十嵐 友樹, 大湊 麗, 林 孝文, 小野 和宏, 高木 律男

    日本口蓋裂学会雑誌   38 ( 2 )   237 - 237   2013.4

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  • 顎矯正手術後に睡眠呼吸障害の改善が認められた両側性唇顎口蓋裂を伴うトリチャーコリンズ症候群の1例

    上杉 崇史, 小野 和宏, 安島 久雄, 児玉 泰光, 森田 修一, 小林 正治, 高木 律男

    日本口蓋裂学会雑誌   38 ( 2 )   209 - 209   2013.4

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  • 粘膜下口蓋裂に関する臨床的検討 言語成績について

    大湊 麗, 小林 孝憲, 児玉 泰光, 小山 貴寛, 永田 昌毅, 飯田 明彦, 小野 和宏, 高木 律男

    日本口蓋裂学会雑誌   38 ( 2 )   224 - 224   2013.4

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  • 粘膜下口蓋裂に関する臨床的検討 診断および治療について

    小林 孝憲, 大湊 麗, 児玉 泰光, 小山 貴寛, 永田 昌毅, 飯田 明彦, 小野 和宏, 高木 律男

    日本口蓋裂学会雑誌   38 ( 2 )   250 - 250   2013.4

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  • 歯根完成歯移植後の歯根頸部吸収

    菅井 登志子, 芳澤 享子, 新美 奏恵, 青山 祥子, 小山 貴寛, 小林 正治, 高木 律男, 小野 和宏, 興地 隆史, 齊藤 力

    日本口腔科学会雑誌   62 ( 1 )   89 - 89   2013.1

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  • 新潟大学医歯学総合病院歯科医師臨床研修単独型プログラムにおけるポートフォリオ評価

    藤井規孝, 中島貴子, 石崎裕子, 伊藤晴江, 奥村暢旦, 興地隆史, 小野和宏, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   32nd   93   2013

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  • 二段階口蓋形成手術法においてFurlow法による軟口蓋形成を施行した片側性完全唇顎口蓋裂児の永久歯列弓形態

    五十嵐 友樹, 高木 律男, 小野 和宏, 朝日藤 寿一, 齋藤 功, 飯田 明彦

    日本形成外科学会会誌   32 ( 11 )   863 - 864   2012.11

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  • 上顎前方移動術による咽頭周囲軟組織の形態変化が口蓋裂患者の言語機能に及ぼす影響

    工藤 和子, 児玉 泰光, 朝日藤 寿一, 小野 和宏, 齊藤 力, 高木 律男, 齋藤 功

    日本歯科医師会雑誌   65 ( 5 )   669 - 669   2012.8

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  • 二段階口蓋形成手術を行った唇顎口蓋裂の外科的矯正治療症例の検討

    福田 純一, 児玉 泰光, 飯田 明彦, 高木 律男, 齋藤 功, 小野 和宏

    日本形成外科学会会誌   32 ( 7 )   510 - 510   2012.7

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  • 新潟大学医歯学総合病院(歯科)における口蓋裂診療班の活動について

    朝日藤 寿一, 小野 和宏, 竹山 雅規, 松山 順子, 八木 稔, 泉 直也, 小山 貴寛, 池 真樹子, 石澤 尚子, かづき れいこ, 小林 正治, 寺田 員人, 齊藤 力, 高木 律男, 齋藤 功

    日本口蓋裂学会雑誌   37 ( 2 )   176 - 176   2012.4

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  • 二段階口蓋形成手術法における硬口蓋裂の大きさがその後の顎発育へ及ぼす影響について

    五十嵐 友樹, 飯田 明彦, 小林 孝憲, 小山 貴寛, 朝日藤 寿一, 小野 和宏, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   37 ( 2 )   152 - 152   2012.4

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  • 唇顎口蓋裂術後の矯正治療に関する臨床統計的調査(第2報)

    竹山 雅規, 吉田 留巳, 小野 和宏, 中川 麻里, 丹原 惇, 朝日藤 一寿, 齊藤 力, 高木 律男, 齋藤 功

    日本口蓋裂学会雑誌   37 ( 2 )   151 - 151   2012.4

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  • 当科における口唇裂口蓋裂患者の臨床統計的観察

    小山 貴寛, 小林 孝憲, 五十嵐 友樹, 児玉 泰光, 福田 純一, 飯田 明彦, 小野 和宏, 高木 律男

    日本口蓋裂学会雑誌   37 ( 2 )   143 - 143   2012.4

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  • 歯根完成歯移植における予後因子の検討

    芳澤 享子, 青山 祥子, 新美 奏恵, 菅井 登志子, 北村 信隆, 小林 正治, 高木 律男, 小野 和宏, 興地 隆史, 齊藤 力

    日本口腔科学会雑誌   61 ( 1 )   202 - 202   2012.1

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  • 大学学習法へのパフォーマンス評価の導入

    小野和宏, 井上誠, 山村健介, 西山秀昌, 八木稔, STEGAROIU Roxana, 重谷佳見, 前田健康, 高橋雄介, 松下佳代

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   31st   141   2012

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  • 留学生交流支援制度(ショートステイ・ショートビジット)プログラムによる歯学部学生の海外派遣

    魚島勝美, 宮崎秀夫, 小野和宏, 興地隆史, 大内章嗣, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   31st   69   2012

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  • 二段階口蓋形成手術法においてFurlow法による軟口蓋形成を施行した片側性完全唇顎口蓋裂児の永久歯列弓形態

    五十嵐 友樹, 飯田 明彦, 小野 和宏, 朝日藤 寿一, 齋藤 功, 高木 律男

    新潟歯学会雑誌   41 ( 2 )   123 - 123   2011.12

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  • 長期管理を行った正中唇裂の1例

    朝日藤 寿一, 森田 修一, 齋藤 功, 小野 和宏, 高木 律男

    日本形成外科学会会誌   31 ( 10 )   721 - 722   2011.10

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  • 顎裂部骨移植術と同時に隣接する側切歯に対し歯胚回転を行った1例

    飯田 明彦, 高木 律男, 小野 和宏, 八巻 正樹, 齋藤 功

    日本形成外科学会会誌   31 ( 10 )   722 - 722   2011.10

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  • 二段階口蓋形成手術を行った唇顎口蓋裂の外科的矯正治療症例の検討

    福田 純一, 児玉 泰光, 飯田 明彦, 高木 律男, 小野 和宏, 朝日藤 寿一, 齋藤 功

    日本顎変形症学会雑誌   21 ( 2 )   86 - 86   2011.5

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  • 長期管理を行なった正中唇裂の一例

    朝日藤 寿一, 小野 和宏, 大野 葉子, 森田 修一, 高木 律男, 齋藤 功

    日本口蓋裂学会雑誌   36 ( 2 )   151 - 151   2011.4

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  • 二段階口蓋形成手術法においてFurlow法による軟口蓋形成を施行した片側性完全唇顎口蓋裂児の永久歯列弓形態

    五十嵐 友樹, 飯田 明彦, 小野 和宏, 朝日藤 寿一, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   36 ( 2 )   99 - 99   2011.4

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  • 口唇裂・口蓋裂患者に施行した歯の自家移植に関する臨床的検討

    小山 貴寛, 飯田 明彦, 芳澤 享子, 小野 和宏, 小林 正治, 齊藤 力, 齋藤 功, 高木 律男

    日本口蓋裂学会雑誌   36 ( 2 )   125 - 125   2011.4

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  • 上顎前方移動術が口蓋裂患者の言語機能に及ぼす影響 Nasometerおよび側面セファログラムによる検討

    工藤 和子, 寺尾 恵美子, 児玉 泰光, 小野 和宏, 高木 律男, 齊藤 力, 齋藤 功

    日本口蓋裂学会雑誌   36 ( 2 )   103 - 103   2011.4

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  • 口蓋裂および下顎切歯先天性欠如を伴うピエール・ロバン連鎖症例

    竹山 雅規, 小野 和宏, 齋藤 功

    日本口蓋裂学会雑誌   36 ( 2 )   149 - 149   2011.4

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  • 上顎左側犬歯の萠出方向異常および下顎両側側切歯の先天性欠如を伴う左側唇顎口蓋裂症例

    中川 麻里, 布田 花子, 小野 和宏, 高木 律男, 齋藤 功

    日本口蓋裂学会雑誌   36 ( 2 )   141 - 141   2011.4

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  • Hotz床併用二段階口蓋形成手術法にFurlow法を用いた片側唇顎口蓋裂児の4歳から8歳までの言語機能

    寺尾 恵美子, 飯田 明彦, 小野 和宏, 五十嵐 友樹, 高木 律男

    日本口蓋裂学会雑誌   36 ( 2 )   104 - 104   2011.4

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  • 放射線誘発と考えられた下顎骨悪性線維性組織球腫の1例

    小山 貴寛, 星名 秀行, 児玉 泰光, 小野 和宏, 高木 律男, 林 孝文, 朔 敬

    新潟医学会雑誌   125 ( 3 )   163 - 164   2011.3

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  • 歯根完成智歯移植の予後因子に関する検討

    菅井 登志子, 芳澤 享子, 小林 正治, 高木 律男, 小野 和宏, 興地 隆史, 齊藤 力

    日本口腔科学会雑誌   60 ( 1 )   94 - 95   2011.1

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  • 歯根完成歯移植の経過と予後因子に関する検討

    青山 祥子, 芳澤 享子, 菅井 登志子, 新美 奏恵, 小林 正治, 高木 律男, 小野 和宏, 興地 隆史, 齊藤 力

    日本口腔科学会雑誌   60 ( 1 )   153 - 154   2011.1

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  • PBLカリキュラムに対する学生の認識

    小野和宏, 八木稔, STEGAROIU Roxana, 大内章嗣, 鈴木昭, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   30th   98   2011

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  • 上顎前方移動術を施行した口蓋裂患者における術後鼻咽腔閉鎖機能への影響 Nasometerと側面セファログラムでの検討

    工藤 和子, 寺尾 恵美子, 朝日藤 寿一, 児玉 泰光, 飯田 明彦, 小野 和宏, 高木 律男, 齋藤 功

    新潟歯学会雑誌   40 ( 2 )   191 - 191   2010.12

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  • 歯根完成歯移植の術後経過と予後因子に関する検討

    青山 祥子, 芳澤 享子, 菅井 登志子, 新美 奏恵, 小林 正治, 高木 律男, 小野 和宏, 興地 隆史, 齊藤 力

    新潟歯学会雑誌   40 ( 1 )   101 - 102   2010.6

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  • 新潟大学における片側性唇顎口蓋裂患者のGoslon Yardstickを用いた咬合評価と矯正治療内容との関連性

    竹山雅規, 渡邉直子, 朝日藤寿一, 森田修一, 毛利環, 小野和宏, 高木律男, 齊藤力, 幸地省子, 須佐美隆史, 齋藤功

    日本口蓋裂学会雑誌   35 ( 2 )   160   2010.4

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  • 上顎前方移動術による口蓋裂術後鼻咽腔閉鎖機能への影響 第2報 Nasometerと側面セファログラムでの検討

    工藤和子, 寺尾恵美子, 朝日藤寿一, 児玉泰光, 飯田明彦, 小野和宏, 高木律男, 齋藤功

    日本口蓋裂学会雑誌   35 ( 2 )   143   2010.4

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  • 顎裂部の側切歯に対し骨移植術と同時に歯胚回転を行った唇顎口蓋裂の1例

    飯田明彦, 高木律男, 小野和宏, 八巻正樹, 齋藤功, 稲見佳大

    日本口蓋裂学会雑誌   35 ( 2 )   131   2010.4

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  • 二段階口蓋形成手術法の硬口蓋閉鎖術前後における鼻咽腔閉鎖機能の検討 硬口蓋閉鎖床の有用性について

    寺尾 恵美子, 飯田 明彦, 小野 和宏, 五十嵐 友樹, 高木 律男

    日本口蓋裂学会雑誌   35 ( 2 )   143 - 143   2010.4

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  • 新潟大学歯学部におけるPBL実施方法の評価―学生の立場から―

    塩生有希, 南智香子, 君雅水, 長澤麻沙子, 小野和宏, 魚島勝美, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   29th   102   2010

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  • 新潟大学歯学部における初年次教育の役割と課題

    小野和宏, 八木稔, STEGAROIU Roxana, 大島勇人, 西山秀昌, 八巻正樹, 鈴木一郎, 朔敬, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   29th   97   2010

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  • 歯根完成歯自家移植の歯根吸収に関する臨床的検討

    新美 奏恵, 芳澤 享子, 菅井 登志子, 小林 正治, 齊藤 力, 高木 律男, 小野 和宏, 興地 隆史

    日本口腔科学会雑誌   58 ( 4 )   287 - 287   2009.9

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  • 歯根完成歯移植後に出現した歯根頸部吸収に関する臨床的検討

    新美 奏恵, 芳澤 享子, 菅井 登志子, 小林 正治, 齊藤 力, 高木 律男, 小野 和宏, 興地 隆史

    日本口腔外科学会雑誌   55 ( Suppl. )   290 - 290   2009.9

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  • 歯根完成歯自家移植における経過不良症例に関する検討

    芳澤 享子, 菅井 登志子, 新美 奏恵, 小林 正治, 齊藤 力, 小野 和宏, 高木 律男, 興地 隆史

    日本口腔外科学会雑誌   55 ( Suppl. )   229 - 229   2009.9

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  • 歯根完成歯自家移植の予後因子に関する検討(第2報)

    菅井 登志子, 芳澤 享子, 小林 正治, 齊藤 力, 高木 律男, 小野 和宏, 興地 隆史

    日本口腔科学会雑誌   58 ( 4 )   236 - 237   2009.9

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  • インプラントに関連した上顎洞合併症の臨床的検討

    池田 順行, 星名 秀行, 小野 和宏, 飯田 明彦, 高木 律男

    新潟歯学会雑誌   39 ( 1 )   90 - 90   2009.6

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  • 単純CTと超音波診断法を用いた顎動脈の走行に関する顎矯正手術前評価

    児玉 泰光, 福田 純一, 田中 礼, 松川 理美, 飯田 明彦, 小野 和宏, 林 孝文, 高木 律男

    日本顎変形症学会雑誌   19 ( 2 )   106 - 106   2009.5

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  • 新潟大学医歯学総合病院矯正歯科診療室における口唇裂・口蓋裂患者の臨床統計調査

    竹山雅規, 朝日藤寿一, 金山潔, 大石めぐみ, 小原彰浩, 小野和宏, 齊藤力, 高木律男, 齋藤功

    日本口蓋裂学会雑誌   34 ( 2 )   221   2009.4

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  • 上顎前方移動術が口蓋裂患者の鼻咽腔閉鎖機能に及ぼす影響について

    工藤和子, 朝日藤寿一, 高木律男, 小野和宏, 寺尾恵美子, 齋藤功, 児玉泰光

    日本口蓋裂学会雑誌   34 ( 2 )   199   2009.4

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  • 二段階口蓋形成手術法における硬口蓋閉鎖に関する長期間一貫治療成績 低年齢での硬口蓋閉鎖の可能性

    飯田 明彦, 永田 昌毅, 五十嵐 友樹, 高木 律男, 児玉 泰光, 小野 和宏, 小山 貴寛, 寺尾 恵美子, 小林 孝憲

    日本口蓋裂学会雑誌   34 ( 2 )   146 - 146   2009.4

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  • 新潟大学歯学部歯学科のカリキュラム評価

    小野和宏, 八木稔, 大内章嗣, 魚島勝美, 林孝文, 齋藤功, 興地隆史, 前田健康, 藤井規孝

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   28th   91   2009

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  • 早期臨床実習への窩洞形成修復実習の導入

    HAN Linlin, 興地隆史, 吉羽永子, 小林哲夫, 藤井規孝, 小野和宏, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   28th   128   2009

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  • 電子ノートシステム構築によるPBL学習支援について(第1報)―コアタイムにおける電子筆記とその評価―

    黒川孝一, 小野和宏, 大内章嗣, 八木稔, STEGAROIU Roxana, 中島俊一, 大瀧祥子, 森田修一, 山崎和久, 鈴木昭, 山田好秋, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   28th   119   2009

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  • 長期管理を行った正中唇裂の1例

    朝日藤寿一, 大野葉子, 小野和宏, 小原彰浩, 森田修一, 高木律男, 齋藤功

    日本矯正歯科学会大会プログラム・抄録集   68th   279   2009

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  • 歯根完成歯自家移植の予後因子に関する検討

    菅井 登志子, 芳澤 享子, 小林 正治, 齊藤 力, 高木 律男, 小野 和宏, 興地 隆史

    日本口腔科学会雑誌   57 ( 4 )   439 - 439   2008.9

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  • 歯根完成歯自家移植の予後因子に関する検討

    菅井 登志子, 芳澤 享子, 小林 正治, 齊藤 力, 高木 律男, 小野 和宏, 北村 信隆, 興地 隆史

    日本歯科医師会雑誌   61 ( 5 )   508 - 508   2008.8

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  • 口唇口蓋裂手術に対する培養複合口腔粘膜の応用

    飯田 明彦, 小山 貴寛, 高木 律男, 芳澤 享子, 小野 和宏

    日本形成外科学会会誌   28 ( 6 )   412 - 412   2008.6

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  • 片側性唇顎口蓋裂患者の成長発育に伴う外鼻形態の変化について

    古里美幸, 高木律男, 森田修一, 齊藤力, 朝日藤寿一, 齋藤功, 小野和宏

    日本口蓋裂学会雑誌   33 ( 2 )   234   2008.4

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  • 口唇口蓋裂手術における培養複合口腔粘膜の応用

    飯田明彦, 小山貴寛, 高木律男, 芳澤享子, 齊藤力, 齋藤功, 小野和宏

    日本口蓋裂学会雑誌   33 ( 2 )   157   2008.4

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  • 骨延長術による上顎歯列弓の拡大を併用して矯正治療を行った片側性唇顎口蓋裂の一例

    竹山雅規, 小野和宏, 高木律男, 齋藤功

    日本口蓋裂学会雑誌   33 ( 2 )   242   2008.4

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  • Hotz床併用二段階口蓋形成手術法における唇顎口蓋裂児の言語評価 ナゾメータによる客観的評価

    寺尾 恵美子, 飯田 明彦, 児玉 泰光, 高木 律男, 永田 昌毅, 小野 和宏

    日本口蓋裂学会雑誌   33 ( 2 )   253 - 253   2008.4

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  • 歯性感染症から進展した高齢者降下性壊死性縦隔炎の1例

    児玉 泰光, 小野 和宏, 嵐山 貴徳, 飯田 明彦, 大関 康志, 土田 正則, 佐藤 裕喜, 高木 律男

    日本口腔科学会雑誌   57 ( 1 )   143 - 143   2008.1

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  • 骨髄移植後のGVHD患者に発生した舌癌の1例

    安島 久雄, 池田 順行, 児玉 泰光, 福田 純一, 飯田 明彦, 小野 和宏, 高木 律男

    日本口腔外科学会雑誌   54 ( 1 )   38 - 38   2008.1

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  • 外傷 当科における顎骨骨折の臨床統計的検討

    小山 貴寛, 飯田 明彦, 永田 昌毅, 福田 純一, 藤田 一, 安島 久雄, 児玉 泰光, 池田 順行, 小林 孝憲, 高木 律男, 小野 和宏, 星名 秀行

    日本口腔科学会雑誌   57 ( 1 )   108 - 108   2008.1

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  • ガイドライン 抗血栓療法患者における歯科観血処置の検討

    山田 裕士, 児玉 泰光, 青柳 貴之, 山中 正文, 小山 貴寛, 斎藤 正直, 池田 順行, 安島 久雄, 藤田 一, 福田 純一, 永田 昌毅, 星名 秀行, 飯田 明彦, 小野 和宏, 古嶋 博司, 相澤 義房, 高木 律男

    日本口腔科学会雑誌   57 ( 1 )   91 - 92   2008.1

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  • 歯科矯正学実習における視覚教材の開発

    渡邉直子, 八巻正樹, 小野和宏, 前田健康, 齋藤功

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   27th   96   2008

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  • 口腔保健と福祉の融合を目指した学習者主体PBLカリキュラムの構築

    小野和宏, 大内章嗣, STEGAROIU Roxana, 八木稔, 黒川孝一, 高橋英樹, 五十嵐敦子, 隅田好美, 石川裕子, 柴田佐都子, 中島俊一, 山崎和久, 福島正義, 富沢美恵子, 鈴木昭, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   27th   79   2008

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  • Surgically‐assisted rapid palatal expansion(SARPE)により上顎の拡大を行った片側性唇顎口蓋裂の一例

    朝日藤寿一, 本間克彦, 小野和宏, 齋藤功

    日本矯正歯科学会大会プログラム・抄録集   67th   244   2008

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  • 歯根完成歯自家移植の予後因子に関する臨床的検討

    菅井 登志子, 芳澤 享子, 小林 正治, 齊藤 力, 小山 貴寛, 高木 律男, 小野 和宏, 興地 隆史

    新潟歯学会雑誌   37 ( 2 )   253 - 253   2007.12

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  • 下顎頭に生じた病変により顎変形を認めた2例

    安島 久雄, 飯田 明彦, 福田 純一, 児玉 泰光, 高木 律男, 小野 和宏

    日本形成外科学会会誌   27 ( 11 )   808 - 808   2007.11

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  • 歯根完成歯自家移植に関する臨床的検討 経過不良症例について

    芳澤 享子, 新美 奏恵, 小林 正治, 齊藤 力, 小野 和宏, 高木 律男

    日本口腔外科学会雑誌   53 ( Suppl. )   176 - 176   2007.8

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  • 歯根完成歯自家移植の予後因子に関する臨床的検討

    菅井 登志子, 芳澤 享子, 小山 貴寛, 小林 正治, 齊藤 力, 小野 和宏, 高木 律男, 興地 隆史

    日本口腔外科学会雑誌   53 ( Suppl. )   175 - 175   2007.8

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  • 当科で行っている下顎枝垂直骨切り術について

    福田 純一, 高木 律男, 飯田 明彦, 児玉 泰光, 小野 和宏, 星野 秀行

    日本形成外科学会会誌   27 ( 6 )   467 - 467   2007.6

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  • 下顎枝垂直骨切り術の選択基準と手術時の工夫について

    福田 純一, 高木 律男, 飯田 明彦, 児玉 泰光, 小野 和宏, 星名 秀行

    日本顎変形症学会雑誌   17 ( 2 )   150 - 150   2007.5

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  • 口唇口蓋裂患者における顎矯正手術に関連した下顎枝の形態学的特徴 軸位断CT画像を用いた下顎孔レベルの計測

    児玉 泰光, 福田 純一, 田中 礼, 小野 和宏, 星名 秀行, 飯田 明彦, 林 孝文, 高木 律男

    日本顎変形症学会雑誌   17 ( 2 )   178 - 178   2007.5

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  • 二段階法による口蓋形成術

    高木律男, 朝日藤寿一, 渡邉直子, 小野和宏, 飯田明彦, 寺尾恵美子, 齋藤功

    日本口蓋裂学会雑誌   32 ( 2 )   112 - 113   2007.4

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  • 新潟大学医歯学総合病院(歯科)における口蓋裂診療班の活動について

    朝日藤寿一, 吉羽邦彦, 竹石英之, 瀬尾憲司, 齊藤力, 寺田員人, 小林正治, 毛利環, 寺尾恵美子, 児玉泰光, 小野和宏, 飯田明彦, 松山順子, 北村絵里子, 高木律男, 八木稔, 櫻井直樹, 田中礼, 齋藤功, かづき れいこ

    日本口蓋裂学会雑誌   32 ( 2 )   163   2007.4

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  • 多発性線維性骨異形成症患者における両側性口唇口蓋裂の治療経験

    児玉泰光, 小野和宏, 高木律男, ソフハン ウバイダス, 小栗由充, 齋藤功, 生越章, 遠藤直人

    日本口蓋裂学会雑誌   32 ( 2 )   267   2007.4

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  • 片側性唇顎口蓋裂症例における上顎歯列弓形態と歯列弓拡大後の変化との関連性(Relapse tendency in the maxillary dental arch widths in UCLP patients with different types of maxillary arch form)

    Al-Gunaid Talat Hasan, 高木 律男, 花田 晃治, 小野 和宏, 齋藤 功, 朝日藤 寿一, 小原 彰浩, 齊藤 力, 八巻 正樹

    日本口蓋裂学会雑誌   32 ( 2 )   225 - 225   2007.4

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  • 全前脳胞症の4例

    飯田 明彦, 安島 久雄, 高木 律男, 児玉 泰光, 小野 和宏, 池田 順行, 福田 純一, 小山 貴寛

    日本口蓋裂学会雑誌   32 ( 2 )   271 - 271   2007.4

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  • 新潟大学医歯学総合病院顎顔面外科診療室における口唇裂口蓋裂患者管理状況の検討

    奈良井 省太, 児玉 泰光, 高木 律男, 小林 孝憲, 福田 純一, 飯田 明彦, 永田 昌毅, 小山 貴寛, 小野 和宏

    日本口蓋裂学会雑誌   32 ( 2 )   241 - 241   2007.4

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  • Hotz床併用二段階口蓋形成手術法にFurlow法を用いた唇顎口蓋裂児の言語機能

    寺尾 恵美子, 飯田 明彦, 児玉 泰光, 高木 律男, 永田 昌毅, 小野 和宏

    日本口蓋裂学会雑誌   32 ( 2 )   226 - 226   2007.4

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  • 新潟大学歯学部における総合模型実習3年間の経験

    魚島勝美, 田中みか子, 小田陽平, 庭野和明, 渡邉清志, 飛田滋, 岡田直人, 長澤麻沙子, 吉田恵子, 小野和宏, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   26th   65   2007

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  • 新潟大学新歯学教育課程の教育効果―生涯学習能力に関する学生の自己評価結果について―

    小野和宏, 魚島勝美, 林孝文, 齋藤功, 八木稔, 大内章嗣, 興地隆史, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   26th   61   2007

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  • 二次的顎裂部骨移植の時期の違いが上顎骨の成長発育におよぼす影響について

    碓井由紀子, 小野和宏, 朝日藤寿一, 高木律男, 齋藤功, 八木稔

    新潟歯学会雑誌   36 ( 2 )   297   2006.12

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  • 歯の移植に関する臨床的検討

    芳澤 享子, 小林 正治, 齊藤 力, 小野 和宏, 高木 律男

    日本形成外科学会会誌   26 ( 10 )   691 - 691   2006.10

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  • カスタムメイド人工骨を用い顔面非対称を改善したHemifacial Microsomiaの1例

    児玉 康光, 高木 律男, 小野 和宏, 福田 純一, 渡邊 直子, 齊藤 功

    日本形成外科学会会誌   26 ( 10 )   691 - 691   2006.10

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  • 唇顎口蓋裂の上顎歯列狭窄に対する骨延長法の応用

    小野 和宏, 小林 正治, 齊藤 力, 福田 純一, 高木 律男, 齋藤 功, 朝日藤 寿一, 竹山 雅規

    日本口腔外科学会雑誌   52 ( Suppl. )   51 - 51   2006.9

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  • 口唇裂・口蓋裂患者に対する管理体制の検討 管理中断症例について

    奈良井 省太, 小林 孝憲, 飯田 明彦, 小山 貴寛, 相田 恵, 児玉 泰光, 福田 純一, 永田 昌毅, 小野 和宏, 高木 律男

    新潟歯学会雑誌   36 ( 1 )   110 - 110   2006.6

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  • 二段階法におけるFurlow法による軟口蓋形成後の硬口蓋裂の推移と硬口蓋閉鎖術について

    飯田 明彦, 高木 律男, 小野 和宏, 永田 昌毅, 寺尾 恵美子, 児玉 泰光

    日本形成外科学会会誌   26 ( 5 )   352 - 352   2006.5

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  • カスタムメイド人工骨を用いて顔面非対称を改善したHemifacial microsomiaの1例

    児玉泰光, 高木律男, 小野和宏, 福田純一, 山中正文, 西山秀昌, 林孝文, 渡邊直子, 齋藤功

    日本顎変形症学会雑誌   16 ( 2 )   81   2006.5

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  • 末端肥大症が疑われた骨格性下顎前突症の1例

    福田純一, 高木律男, 小野和宏, 児玉泰光, 山中正文, 齋藤功, 川原のぞみ

    日本顎変形症学会雑誌   16 ( 2 )   78   2006.5

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  • 日本における片側性唇顎口蓋裂治療に関する多施設共同研究‐Part7 多施設共同研究の問題点について‐

    朝日藤寿一, 小野和宏, 森田修一, 毛利環, 高木律男, 寺尾恵美子, 幸地省子, 須佐美隆史, 倉林仁美, 岩田敏男, 舘村卓, 根来武史, 大塚純正, 齋藤功

    日本口蓋裂学会雑誌   31 ( 2 )   93   2006.4

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  • 唇顎口蓋裂術後の矯正治療に関する臨床統計的調査‐二段階口蓋形成法と一段階形成法との比較‐

    竹山雅規, 齊藤力, 宮城尚史, 高木律男, 中川麻里, 齋藤功, 小野和宏

    日本口蓋裂学会雑誌   31 ( 2 )   210   2006.4

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  • 二次的顎裂部骨移植の時期の違いが上顎骨の成長発育におよぼす影響について

    碓井由紀子, 高木律男, 小野和宏, 齋藤功, 朝日藤寿一, 幸地省子

    日本口蓋裂学会雑誌   31 ( 2 )   164   2006.4

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  • 口蓋裂患者に対する上顎前方移動術が鼻咽腔閉鎖機能に及ぼす影響‐ナゾメーターを用いた客観的検討‐

    児玉泰光, 飯田明彦, 山中正文, 小野和宏, 福田純一, 奈良井省太, 高木律男, 碓井由紀子, 小林孝憲, 永田昌毅, 寺尾恵美子, 齋藤功

    日本口蓋裂学会雑誌   31 ( 2 )   224   2006.4

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  • 二段階法におけるFurlow法による軟口蓋形成術の術中・術後経過について

    飯田 明彦, 高木 律男, 小野 和宏, 永田 昌毅, 寺尾 恵美子, 児玉 泰光, 小山 貴寛, 小林 孝憲, 奈良井 省太

    日本口蓋裂学会雑誌   31 ( 2 )   219 - 219   2006.4

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  • 下顎枝垂直骨切り術直後に骨片の接触不良が認められた症例の検討

    福田 純一, 高木 律男, 小野 和宏, 星名 秀行, 飯田 明彦, 児玉 泰光

    日本形成外科学会会誌   26 ( 4 )   291 - 291   2006.4

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  • Hotz床併用二段階口蓋形成手術を行った片側性唇顎口蓋裂患者の外鼻形態の成長変化

    古里 美幸, 森田 修一, 朝日藤 寿一, 竹村 史, 小野 和宏, 高木 律男, 齊藤 力, 齋藤 功

    新潟歯学会雑誌   35 ( 2 )   252 - 252   2006.1

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  • 問題基盤型学習による高度専門職業人育成カリキュラム(予報)

    小野和宏, 大内章嗣, ROXANA Stegaroiu, 八木稔, 石川裕子, 隅田好美, 中島俊一, 五十嵐敦子, 黒川孝一, 鈴木昭, 山崎和久, 福島正義, 富沢美恵子, 山田好秋, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   25th   82   2006

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  • 新潟大学におけるGoslon Yardstickによる片側性唇顎口蓋裂症例の咬合評価―2段階口蓋形成術の影響について―

    朝日藤寿一, 渡邉直子, 渡辺厚, 小原彰浩, 金山潔, AL‐GUNAID R, 毛利環, 森田修一, 寺田員人, 高木律男, 齊藤力, 小野和宏, 須佐美隆史, 幸地省子, 齋藤功

    日本矯正歯科学会大会プログラム・抄録集   65th   273   2006

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  • 片側性唇顎口蓋裂患者の成長発育に伴う外鼻形態の変化について

    古里美幸, 森田修一, 朝日藤寿一, 竹村史, 小野和宏, 高木律男, 齊藤力, 齋藤功

    日本矯正歯科学会大会プログラム・抄録集   65th   273   2006

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  • 下顎枝垂直骨切り術後骨片の接触が不良であった症例の検討

    福田 純一, 高木 律男, 小野 和宏, 星名 秀行, 飯田 明彦, 児玉 泰光

    日本顎変形症学会雑誌   15 ( 3 )   173 - 173   2005.12

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  • 矯正治療により歯の移動が不可能であった歯に対する外科的治療

    津端 久美子, 福田 純一, 高木 律男, 小野 和宏, 越知 佳奈子, 中川 公貴, 寺田 員人

    日本顎変形症学会雑誌   15 ( 3 )   192 - 193   2005.12

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  • 歯の即時自家移植の臨床的検討 受容部抜歯時期について

    小山 貴寛, 芳澤 享子, 小野 和宏, 小林 正治, 齊藤 力, 高木 律男

    日本口腔外科学会雑誌   51 ( Suppl. )   237 - 237   2005.9

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  • 歯の即時自家移植に関する臨床的検討

    芳澤 享子, 小林 正治, 齊藤 力, 小野 和宏, 高木 律男

    日本口腔科学会雑誌   54 ( 4 )   536 - 537   2005.9

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  • 歯の移植における予後不良因子の検討 移植歯・受容部ともに問題のあった症例

    安島 久雄, 福田 純一, 小野 和宏, 高木 律男, 芳澤 享子, 泉 直也, 齋藤 力

    日本口腔科学会雑誌   54 ( 4 )   435 - 435   2005.9

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  • Roles of hepatocyte growth factor in bone metastasis of a mouse mammary cancer cell line, BALB/c-MC.

    K Ono, S Kamiya, T Akatsu, N Kugai, M Li, N Amizuka, K Matsumoto, T Nakamura, S Wada

    JOURNAL OF BONE AND MINERAL RESEARCH   20 ( 9 )   S214 - S214   2005.9

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  • 新潟大学医歯学総合病院口腔外科における骨移植・インプラント症例の検討

    庭野 将広, 星名 秀行, 小野 和宏, 飯田 明彦, 高木 律男, 加納 浩之, 小島 拓, 小林 正治, 高田 佳之, 齊藤 力

    新潟歯学会雑誌   35 ( 1 )   89 - 89   2005.7

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  • 歯の凍結保存と移植

    芳澤 享子, 新美 奏恵, 小野 由起子, 加納 浩之, 小林 正治, 齊藤 力, 飯田 明彦, 小野 和宏, 高木 律男

    歯界展望   特別号 ( 健康な心と身体は口腔から-発ヨコハマ2004- )   341 - 341   2005.6

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  • Psychiatric and psychological approach of rehabilitation makeup therapy

    KAZKI Reiko

    日本口蓋裂学会雑誌   30 ( 2 )   219 - 219   2005.4

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  • Audience's Perception for the Multi-center Collaborative CLP Research Project in Japan

    MOHRI Tamaki

    30 ( 2 )   220 - 220   2005.4

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  • 片側性完全口唇口蓋裂治療管理の比較 push back法と二段階法

    幸地 省子, 古里 美幸, 寺尾 恵美子, 石澤 優子, 小野 和宏, 森田 修一, 北 浩樹, 山田 敦, 朝日藤 寿一, 高木 律男, 台丸谷 隆慶, 小山 貴寛, 齋藤 功, 大澤 雅輝

    日本口蓋裂学会雑誌   30 ( 2 )   93 - 93   2005.4

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  • 多施設共同研究にむけた資料採取の基準作成

    小野 和宏, 森田 修一, 須佐美 隆史, 朝日藤 寿一, 寺尾 恵美子, 大塚 純正, 毛利 環, 高木 律男, 根来 武史, 八巻 正樹, 幸地 省子, 舘村 卓

    日本口蓋裂学会雑誌   30 ( 2 )   141 - 141   2005.4

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  • 新潟大学におけるGoslon Yardstickを用いた片側性口唇裂口蓋裂患者の咬合評価 2段階口蓋形成手術の影響

    渡邉 直子, 寺田 員人, 須佐美 隆史, 朝日藤 寿一, 小野 和宏, 幸地 省子, 森田 修一, 高木 律男, 齋藤 功, 毛利 環, 齊藤 力

    日本口蓋裂学会雑誌   30 ( 2 )   140 - 140   2005.4

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  • 日本における片側性性唇顎口蓋裂治療に関する多施設比較研究 Part6正面セファログラムの評価結果について

    森田 修一, 須佐美 隆史, 小野 和宏, 毛利 環, 大塚 純正, 高木 律男, 朝日藤 寿一, 根来 武史, 寺尾 恵美子, 幸地 省子, 舘村 卓, 齋藤 功

    日本口蓋裂学会雑誌   30 ( 2 )   200 - 200   2005.4

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  • Furlow法を用いたHotz床併用二段階口蓋形成手術法による言語機能 4歳時から硬口蓋閉鎖術後までの評価

    寺尾 恵美子, 高木 律男, 小野 和宏, 永田 昌毅, 飯田 明彦

    日本口蓋裂学会雑誌   30 ( 2 )   137 - 137   2005.4

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  • 上顎歯列の狭窄を伴う顎変形症に対して,Le Fort I型骨切り術に正中分割を加えた2例

    津端 久美子, 福田 純一, 高木 律男, 小野 和宏, 山中 正文

    日本形成外科学会会誌   25 ( 3 )   239 - 239   2005.3

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  • 両側性口唇口蓋裂を伴ったMcCune-Albright症候群患者における顎裂部腸骨移植術の治療経験

    児玉 泰光, 高木 律男, 小野 和宏, 永田 昌毅, 飯田 明彦, 安島 久雄

    日本口腔科学会雑誌   54 ( 1 )   150 - 150   2005.1

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  • 口蓋裂患者の上顎劣成長 予防と対処 顎発育に配慮した当科の口唇口蓋裂の一貫治療 Hotz床併用二段階口蓋形成手術を中心に

    高木 律男, 福田 純一, 小野 和宏, 飯田 明彦

    日本口腔科学会雑誌   54 ( 1 )   67 - 67   2005.1

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  • PBLチュートリアルにおける学生の学習態度に関する評価

    安島久雄, 小山貴寛, 小野和宏, 高木律男, 小林正治, TEI Jun, 瀬尾憲司, 西山秀昌, 林孝文, 斎藤功, 前田健康, 山田好秋

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   24th   110   2005

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  • 新潟大学歯学部教員を対象としたPBLに関するワークショップの経験

    藤井規孝, 魚島勝美, 高木律男, 興地隆史, 斎藤功, 小野和宏, 林孝文, 山村健介, 中島貴子, 山田好秋, 宮崎秀夫, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   24th   45   2005

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  • 歯科医学教育へのPBLチュートリアル導入に対する学生の評価

    小野和宏, 林孝文, 前田健康, 小林正治, 安島久雄, 瀬尾憲司, CHENG Jun, 斎藤功, 西山秀昌

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   24th   110   2005

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  • PBLにおけるケースシナリオのweb配信システムの導入

    林孝文, 安島久雄, 斎藤功, 小野和宏, 山田好秋, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   24th   56   2005

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  • 日本人家系における唇裂・唇顎口蓋裂発症に関する候補遺伝子(F13A1,D16S539,BCL3)の解析

    大久保 博基, 藤田 一, 永田 昌毅, 小野 和宏, 高木 律男

    新潟医学会雑誌   118 ( 12 )   712 - 712   2004.12

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  • 下顎後退症に対する下顎枝矢状分割術にovercorrectionを行った症例の安定性と顎関節への影響について

    福田 純一, 高木 律男, 小野 和宏, 星名 秀行, 飯田 明彦, 児玉 泰光

    日本顎変形症学会雑誌   14 ( 3 )   230 - 230   2004.12

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  • 上顎歯列の狭窄を伴う顎変形症に対して,Le Fort I型骨切り術に正中分割を加えた2例

    山中 正文, 福田 純一, 高木 律男, 小野 和宏, 星名 秀行, 飯田 明彦, 児玉 泰光

    日本顎変形症学会雑誌   14 ( 3 )   210 - 211   2004.12

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  • 二段階口蓋形成手術を施行した唇顎口蓋裂症例の顎発育 成長終了時の顎骨形態と咬合について

    福田 純一, 高木 律男, 小野 和宏, 永田 昌毅, 飯田 明彦, 児玉 泰光

    日本形成外科学会会誌   24 ( 8 )   528 - 528   2004.8

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  • 歯の凍結保存と移植

    芳澤 享子, 新美 奏恵, 小野 由起子, 加納 浩之, 小林 正治, 齊藤 力, 飯田 明彦, 小野 和宏, 高木 律男

    日本歯科医師会雑誌   57 ( 4 )   434 - 434   2004.7

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  • 小児開口障害の2例

    安島 久雄, 高木 律男, 今井 信行, 飯田 明彦, 小野 和宏

    小児口腔外科   14 ( 1 )   52 - 52   2004.6

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  • 日本における片側性唇顎口蓋裂治療に関する多施設比較研究(Part 5) 音声言語成績のための評価案と試用結果

    舘村 卓, 幸地 省子, 北井 則行, 森田 修一, 寺尾 恵美子, 須佐美 隆史, 朝日藤 寿一, 和田 健, 小野 和宏, 大塚 純正, 石井 一裕, 花田 晃治, 高木 律男, 根来 武史, 毛利 環

    日本口蓋裂学会雑誌   29 ( 2 )   188 - 188   2004.4

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  • Blepharo-cheilo-dontic(BCD)症候群の1例

    飯田 明彦, 永田 昌毅, 奈良井 省太, 池田 順行, 高木 律男, 小野 和宏

    日本口蓋裂学会雑誌   29 ( 2 )   174 - 174   2004.4

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  • Hotz床併用二段階口蓋形成手術を行った片側性唇顎口蓋裂患者における外鼻形態の成長変化

    古里 美幸, 小野 和宏, 森田 修一, 高木 律男, 朝日藤 寿一, 齊藤 力, 竹村 史, 花田 晃治

    日本口蓋裂学会雑誌   29 ( 2 )   150 - 150   2004.4

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  • 日本における片側性唇顎口蓋裂治療に関する多施設比較研究(Part 2) 顎顔面形態の評価結果について

    森田 修一, 石井 一裕, 須佐美 隆史, 舘村 卓, 朝日藤 寿一, 高木 律男, 大塚 純正, 花田 晃治, 小野 和宏, 寺尾 恵美子, 根来 武史, 毛利 環, 幸地 省子, 北井 則行

    日本口蓋裂学会雑誌   29 ( 2 )   185 - 185   2004.4

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  • 日本における片側性唇顎口蓋裂治療に関する多施設比較研究(Part 1) 研究の概要について

    朝日藤 寿一, 大塚 純正, 毛利 環, 寺尾 恵美子, 小野 和宏, 根来 武史, 石井 一裕, 花田 晃治, 幸地 省子, 北井 則行, 高木 律男, 須佐美 隆史, 森田 修一, 舘村 卓

    日本口蓋裂学会雑誌   29 ( 2 )   184 - 184   2004.4

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  • 著明な顎骨の非対称を呈した進行性顔面半側萎縮症の1例

    児玉 泰光, 高木 律男, 小野 和宏, 飯田 明彦, 福田 純一, 朝日 寿一

    日本形成外科学会会誌   24 ( 4 )   278 - 278   2004.4

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  • 日本における片側性唇顎口蓋裂治療に関する多施設比較研究(Part 4) 口唇・外鼻形態の評価結果について

    根来 武史, 八巻 正樹, 幸地 省子, 舘村 卓, 朝日藤 寿一, 小野 和宏, 大塚 純正, 寺尾 恵美子, 毛利 環, 高木 律男, 須佐美 隆史, 後藤 滋巳, 森田 修一, 石井 一裕, 北井 則行, 花田 晃治

    日本口蓋裂学会雑誌   29 ( 2 )   187 - 187   2004.4

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  • 日本における片側性唇顎口蓋裂治療に関する多施設比較研究(Part 3) 咬合状態の評価結果について

    須佐美 隆史, 幸地 省子, 小野 和宏, 寺尾 恵美子, 朝日藤 寿一, 大塚 純正, 舘村 卓, 高戸 毅, 根来 武史, 毛利 環, 石井 一裕, 高木 律男, 北井 則行, 森田 修一, 荻原 祐二, 花田 晃治

    日本口蓋裂学会雑誌   29 ( 2 )   186 - 186   2004.4

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  • 日本人家系における唇裂・唇顎口蓋裂発症に関する候補遺伝子(F13A1,D16S539,BCL3)の解析

    大久保 博基, 飯田 明彦, 寺尾 恵美子, 奈良井 省太, 藤田 一, 福田 純一, 相田 恵, 高木 律男, 永田 昌毅, 碓井 由紀子, 小山 貴寛, 小野 和宏, 児玉 泰光, 小林 孝憲

    日本口蓋裂学会雑誌   29 ( 2 )   202 - 202   2004.4

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  • Three-dimensional evalution of mid-facial development in unilateral cleft lip and palate patients(共著)

    GRAMATICESCU Carmen-Elena, TERADA Kazuto, ISHII Kazuhiro, WATANABE Naoko, ONO Kazuhiro, MORITA Shuichi, HANADA Kooji

    Orthodontic Waves   63 ( 2 )   40 - 47   2004

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    This study investigates the effects of the two stage palatoplasty combined with Hotz' plate on sagittal midfacial development in complete unilateral cleft lip and palate (UCLP) individuals, using an optical surface scanner. The sample included 48 UCLP patients (age : 10-19) treated by two different surgical techniques : one-stage palatoplasty and two-stage palatoplasty and 24 age- and gender-matched non-cleft subjects with skeletal Class I. Facial depth was determined by evaluating the z-coordinate values of 15 corresponding facial measurement points on both sides for each cleft group and the control group. Mid-facial depth asymmetry was obtained by calculating the difference between both sides in z-coordinate values of these 15 corresponding facial measurement points between both sides for cleft groups and left and right sides for the control group and then evaluated by paired t-test. The differences among the three groups were statistically compared by ANOVA's Fisher ratio, at a significance level of p<0.05. Mid-facial depth assessment revealed significant differences (p<0.05) between the three groups, in almost all the measurement points values calculated. No significant difference was found in the case of sagittal mid-facial asymmetry, except on the level of exocanthion plane in the one-stage palatoplasty group. The study clearly demonstrates that two-stage palatoplasty combined with Hotz' plate has a beneficial effect on mid-facial development and facial balance in UCLP patients.

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    Other Link: https://projects.repo.nii.ac.jp/?action=repository_uri&item_id=198636

  • 新潟大学歯学部におけるFDワークショップの試み

    藤井規孝, 魚島勝美, 高木律男, 興地隆史, 斎藤功, 小野和宏, 山村健介, 中島貴子, 山田好秋, 宮崎秀夫, 前田健康

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   23rd   31   2004

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  • 急性期脳卒中患者の簡易予後予測--特定因子による検討

    鈴木 誠, 大内 厚, 渡辺 静恵, 足利谷 美砂, 濱本 宜興, 小野 和宏

    リハビリテーションネットワーク研究   2 ( 1 )   65 - 69   2004

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    Other Link: http://hdl.handle.net/10191/19198

  • 歯根完成歯の即時自家移植後に歯根頸部吸収を認めた2例

    新美 奏恵, 芳澤 享子, 小林 正治, 齊藤 力, 小野 和宏, 高木 律男

    日本口腔外科学会雑誌   49 ( 13 )   878 - 878   2003.12

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  • 顎口腔領域癌患者における上部消化管内視鏡検査(GIF)の検討

    山中 正文, 飯田 明彦, 高木 律男, 小野 和宏, 星名 秀行, 藤田 一, 長島 克弘, 池田 順行, 福田 純一

    新潟医学会雑誌   49(5): 329-334 ( 12 )   760 - 761   2003.12

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    DOI: 10.5794/jjoms.49.329

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  • 精神発達遅滞を有する患者に対する外科的矯正治療の経験

    福田 純一, 高木 律男, 小野 和宏, 飯田 明彦, 星 隆夫

    日本顎変形症学会雑誌   13 ( 3 )   188 - 189   2003.12

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  • 著明な顎骨の非対称を呈した進行性顔面半側萎縮症の1例

    児玉 泰光, 高木 律男, 小野 和宏, 福田 純一, 朝日藤 寿一

    日本顎変形症学会雑誌   13 ( 3 )   189 - 189   2003.12

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  • 凍結保存歯自家移植に関する臨床的検討

    芳澤 享子, 新美 奏恵, 小野 由起子, 加納 浩之, 小林 正治, 齊藤 力, 井上 達夫, 小野 和宏, 高木 律男

    日本口腔外科学会雑誌   49 ( 13 )   796 - 796   2003.12

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  • 歯の即時自家移植の適応症に関する検討 特に適応外症例について

    泉 直也, 芳澤 享子, 橋本 英美, 小林 正治, 齊藤 力, 小野 和宏, 安島 久雄, 高木 律男, 毛利 環, 八巻 正樹, 興地 隆史

    日本口腔外科学会雑誌   49 ( 13 )   795 - 795   2003.12

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  • Molecular genetics of cleft lip and /or palate in Japanese

    FUJITA Hajime, NAGATA Masaki, ONO Kazuhiro

    Niigata dental journal   33 ( 2 )   107 - 109   2003.12

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    Other Link: http://search.jamas.or.jp/link/ui/2004181239

  • 若年者の顎矯正手術後に生じた深部静脈血栓症の1例

    津端 久美子, 福田 純一, 高木 律男, 小野 和宏, 藤田 一

    日本口腔科学会雑誌   52 ( 6 )   378 - 378   2003.11

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  • 手術・化学・高気圧酸素療法を併用した下顎骨骨髄炎症例の臨床的検討

    飯田 明彦, 高木 律男, 小野 和宏, 星名 秀行, 永田 昌毅, 福田 純一, 鈴木 英弘, 児玉 泰光

    日本口腔科学会雑誌   52 ( 6 )   408 - 408   2003.11

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  • 口腔外科手術における腸骨採取術の安全性に関する臨床的検討

    児玉 泰光, 高木 律男, 小野 和宏, 星名 秀行, 永田 昌毅, 飯田 明彦, 藤田 一, 碓井 由紀子, 青山 玲子, 相田 恵, 大久保 博基

    日本口腔科学会雑誌   52 ( 6 )   389 - 389   2003.11

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  • Long-term results of the two-stage palatoplasty/Hotz&apos; plate approach for complete bilateral cleft lip, alveolus and palate patients

    AEQ Silvera, K Ishii, T Arai, S Morita, K Ono, A Iida, K Hanada, R Takagi

    JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY   31 ( 4 )   215 - 227   2003.8

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    Purpose: To investigate the effects of the two-stage palatoplasty combined with the Hotz&apos; plate on craniofacial development in patients with bilateral complete clefts. Material and methods: Lateral and frontal cephalograms of two-stage palatoplasty/Hotz&apos; plate group (n=10), one-stage palatoplasty group (n=11), and a non-cleft group (n=11), were evaluated at 6, 8, 10 and 12 years of age. The unpaired Student&apos;s t-test and Scheffe&apos;s F test (p&lt;0.05) were applied. Results: At 6 years the posterior upper facial height (PUFH) and PUFH/PFH ratio were greater in the two-stage group. At 10 years the PUFH, maxillary depth, convexity and ANB angle were greater in the same group. At 12 years, maxillary depth and ANB angle were also greater in this group. In the one-stage group, the L1/Mp. angle, PUFH and PUFH/PFH ratio were smaller when compared with the non-cleft group, whereas the palatal plane/SN angle was greater. In both cleft groups, the I.I. angle and tongue-PTM&apos; distance were greater, and the U1/SN angle was smaller when compared with non-clefts. The UC-UC&apos; and the ratios UC/MAX and UC/LC of both cleft groups were also smaller when compared with non-clefts. The ratio UM/MAX of the one-stage group was smaller when compared with the non-cleft group. Conclusion: The two-stage palatoplasty in combination with application of the Hotz&apos; plate had good effects on the maxillary growth up to the age of 12 years. (C) 2003 European Association for Cranio-Maxillofacial Surgery.

    DOI: 10.1016/S1010-5182(03)00023-4

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  • 大学院学生を対象にしたProfessional Writingの開講

    相田 恵, 前田 健康, 魚島 勝美, 興地 隆史, 小野 和宏, 高木 律男, 花田 晃治, 山田 好秋

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   22回   52 - 52   2003.7

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  • 精神発達遅滞を有する患者に対する外科的矯正治療の経験

    福田 純一, 高木 律男, 小野 和宏, 飯田 明彦, 藤田 一, 早津 誠

    日本形成外科学会会誌   23 ( 7 )   463 - 463   2003.7

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  • 歯学教育プログラムへのPBL教育の導入 南カリフォルニア大学歯学部における実態調査

    小野 和宏, 前田 健康, 花田 晃治, 山田 好秋, 高木 律男, 興地 隆史, 魚島 勝美, 葭原 明弘, 永田 昌毅, 安島 久雄

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   22回   52 - 52   2003.7

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  • 新潟大学歯学部卒前教育へのOSCEの導入(第2報) コミュニケーション能力の評価

    興地 隆史, 福島 正義, 葭原 明弘, 田井 秀明, 高田 佳之, 小野 和宏, 小林 博, 魚島 勝美, 富沢 美恵子, 高木 律男, 前田 健康, 山田 好秋, 花田 晃治

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   22回   41 - 41   2003.7

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  • 大学学習法としての歯学スタディスキルズ

    前田 健康, 魚島 勝美, 興地 隆史, 小野 和宏, 高木 律男, 花田 晃治, 山田 好秋

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   22回   33 - 33   2003.7

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  • 母親の運転する自転車前方部に乗車中転倒し生じた小児関節突起完全骨折の2例

    小林 孝憲, 高木 律男, 小野 和宏, 飯田 明彦, 碓井 由紀子, 安島 久雄

    小児口腔外科   13 ( 1 )   42 - 42   2003.6

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  • 歯槽骨外科により咬合再建した下顎前歯部中心性血管腫の1例

    小野 和宏, 飯田 明彦, 福田 純一, 高木 律男, 毛利 環, 橋本 明彦

    日本形成外科学会会誌   23 ( 5 )   337 - 338   2003.5

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  • リハビリメイクの紹介と医療連携

    かづき れいこ, 飯田 明彦, 寺田 員人, 高木 律男, 朝日藤 寿一, 小林 正治, 花田 晃治, 齊藤 力, 小野 和宏, 長田 文子

    日本口蓋裂学会雑誌   28 ( 2 )   197 - 197   2003.4

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  • 我が国における唇顎口蓋裂患者の多施設比較研究 科学的基盤を有した唇顎口蓋裂治療を目指して

    小野 和宏, 幸地 省子, 高戸 毅, 夏目 長門, 舘村 卓, 花田 晃治, 真田 武彦, 萩原 祐二, 北井 則行, 和田 健, 石井 一裕, 山田 敦, 根来 武史, 高田 健治, Semb Gunvor, 朝日藤 寿一, 大塚 純正, 後藤 滋巳, 古郷 幹彦, 森田 修一, 大久保 文雄, 栗田 賢一, 小原 浩, 高木 律男, 保坂 善昭, 吉田 憲司, 由良 義明, 寺尾 恵美子, 須佐美 隆史, 下郷 和雄, 森 悦秀

    日本口蓋裂学会雑誌   28 ( 2 )   179 - 179   2003.4

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  • 歯の移植の科学

    河野 正司, 花田 晃治, 前田 健康, 吉江 弘正, 高木 律男, 齊藤 力, 興地 隆史, 小野 和宏, 小林 正治, 八巻 正樹, 芳澤 享子, 村田 雅史, 澤田 宏二, 布川 寧子

    The Quintessence   22 ( 1 )   9 - 20   2003.1

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  • Scientific approach to auto transplantation of teeth

    The Quintessence   22   9 - 20   2003

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  • Introduction of OSCE for Assessment of Clinical Competence in Undergraduate Dental Education at Niigata University School of Dentisty

    The Journal of Japanese Dental Education Association   18   300 - 307   2003

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  • 先天的な下顎頭形態異常を有する患者の臨床的観察

    井上 達夫, 高木 律男, 小野 和宏, 飯田 明彦, 小林 龍彰, 福田 純一, 安島 久雄

    日本口腔外科学会雑誌   48 ( 13 )   847 - 847   2002.12

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  • 当科における上下顎移動術施行症例の臨床統計学的観察

    福田 純一, 高木 律男, 星名 秀行, 小野 和宏

    日本顎変形症学会雑誌   12 ( 3 )   150 - 150   2002.12

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  • 顎矯正手術後の成長により再び非対称を生じた下顎非対称の1例

    児玉 泰光, 高木 律男, 星名 秀行, 小野 和宏, 福田 純一, 八巻 正樹

    日本顎変形症学会雑誌   12 ( 3 )   131 - 131   2002.12

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  • 石灰化歯原性嚢胞5例の臨床病理学的検討

    奈良井 省太, 福田 純一, 高木 律男, 小野 和宏, 星名 秀行, 藤田 一, 長島 克弘, 平 周三, 丸山 智, 朔 敬

    新潟歯学会雑誌   32 ( 2 )   355 - 356   2002.12

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  • Furlow法を施行した口蓋裂児の言語成績

    寺尾 恵美子, 小野 和宏, 永田 昌毅, 飯田 明彦, 早津 誠, 高木 律男

    新潟歯学会雑誌   32 ( 2 )   343 - 343   2002.12

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  • 歯根完成歯移植後の歯根吸収に関する臨床的検討

    新美 奏恵, 芳澤 享子, 川上 美貴, 濱本 宜興, 小林 正治, 齊藤 力, 小野 和宏, 高木 律男

    日本口腔外科学会雑誌   48 ( 13 )   840 - 840   2002.12

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  • 歯槽骨外科により咬合再建した下顎前歯部中心性血管腫(術後)の1例

    小野 和宏, 小林 正治, 毛利 環, 森田 修一, 橋本 明彦, 高木 律男

    日本口腔外科学会雑誌   48 ( 13 )   760 - 760   2002.12

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  • 両側下顎関節突起欠損の1例

    飯田 明彦, 高木 律男, 小林 龍彰, 小野 和宏, 福田 純一, 田中 裕

    日本口腔科学会雑誌   51 ( 6 )   539 - 539   2002.11

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  • 二段階法における軟口蓋閉鎖後の硬口蓋裂の推移に関する検討 Furlow法による軟口蓋閉鎖

    早津 誠, 小野 和宏, 飯田 明彦, 永田 昌毅, 寺尾 恵美子, 高木 律男

    日本形成外科学会会誌   22 ( 11 )   797 - 797   2002.11

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  • 智歯の移植に関する臨床的検討

    川上 美貴, 芳澤 享子, 小林 正治, 泉 健次, 齋藤 力, 安島 久雄, 小野 和宏, 高木 律男

    日本口腔科学会雑誌   51 ( 6 )   514 - 515   2002.11

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  • 悪性を疑わせた高齢者の上顎骨中心性血管腫の1例

    小山 貴寛, 高木 律男, 小野 和宏, 飯田 明彦, 安島 久雄, 林 孝文, 程 くん, 朔 敬

    日本口腔科学会雑誌   51 ( 6 )   435 - 435   2002.11

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  • 両側性唇顎口蓋裂患児に対するHotz床併用二段階口蓋形成手術法の顎発育に関する検討

    早津 誠, 小野 和宏, 飯田 明彦, 永田 昌毅, 高木 律男

    日本形成外科学会会誌   22 ( 10 )   736 - 736   2002.10

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  • The localization of macrophage and lymphocytes in bone metastasized lesions.

    T Sasaki, K Ono, T Akatsu, N Kugai, T Maeda, N Amizuka

    JOURNAL OF BONE AND MINERAL RESEARCH   17   S311 - S311   2002.9

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  • 顎口腔領域の癌患者に対する上部消化管内視鏡検査の有用性

    山中 正文, 飯田 明彦, 高木 律男, 小野 和宏, 星名 秀行, 藤田 一, 長島 克弘, 早津 誠, 池田 順行

    新潟歯学会雑誌   32 ( 1 )   119 - 120   2002.7

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  • 新潟大学歯学部卒前教育へのOSCEの導入

    興地 隆史, 福島 正義, 葭原 明弘, 子田 晃一, 小野 和宏, 小林 博, 魚島 勝美, 小山 純市, 植田 耕一郎, 高木 律男, 前田 健康, 花田 晃治

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   21回   52 - 52   2002.7

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  • IMFスクリューによる顎間骨固定を施行した下顎枝垂直骨切り術の術後安定性

    福田 純一, 高木 律男, 小野 和宏, 星名 秀行, 永田 昌毅, 飯田 明彦

    日本形成外科学会会誌   22 ( 7 )   534 - 534   2002.7

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  • 顎裂部への二次的骨移植に関する臨床統計的観察

    碓井 由紀子, 高木 律男, 小野 和宏, 永田 昌毅, 飯田 明彦, 今井 信行, 早津 誠

    小児口腔外科   12 ( 1 )   42 - 43   2002.6

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  • 新潟大学歯学部附属病院における唇顎口蓋裂患者の管理・治療について

    小野 和宏, 石井 一裕

    Monograph of Clinical Orthodontics   23   1 - 17   2002.4

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  • Furlow法を施行した口蓋裂児の言語成績

    寺尾 恵美子, 早津 誠, 高木 律男, 小野 和宏, 永田 昌毅, 飯田 明彦

    日本口蓋裂学会雑誌   27 ( 2 )   190 - 190   2002.4

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  • 二段階法における軟口蓋閉鎖後の硬口蓋裂の推移に関する検討 Furlow法による軟口蓋閉鎖施行症例について

    早津 誠, 児玉 泰光, 小野 和宏, 寺尾 恵美子, 飯田 明彦, 高木 律男, 永田 昌毅, 大橋 靖, 碓井 由紀子

    日本口蓋裂学会雑誌   27 ( 2 )   151 - 151   2002.4

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  • Clinical study of secondary bone grafting using autogenous particulate cancellous bone and marron harvested from the illiac creast in alveolar clefts

    Niigata Dent. J.   32   53 - 61   2002

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  • Longitudinal Observation of Maxillofacial focical Morphology in a Pair of Monozygotic Twins with Cleft Lip and Palate -Effects of Two-stage palatoplasty on Maxillofacial Development-

    J. Jpn. Cleft. Palate.Assoc.   27(3), 339-349   2002

  • Clinical and Statistieal Evaluation of Cleft Palate Team Activities at Niigata University Dental Hospital

    J. Jpn. Cleft Palate Assoc.   27   297 - 305   2002

  • 骨延長術を用いて治療した骨性癒着歯の1例

    小野 和宏, 高木 律男, 飯田 明彦, 福田 純一, 青山 玲子, 池田 順行, 阿部 裕子

    日本口腔外科学会雑誌   47 ( 13 )   925 - 925   2001.12

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  • 両側性唇顎口蓋裂児に対するHotz床併用二段階口蓋形成手術法の顎発育に関する検討

    早津 誠, 小野 和宏, 飯田 明彦, 永田 昌毅, 今井 信行, 高木 律男, 大橋 靖, 花田 晃治, 森田 修一, 石井 一裕

    新潟歯学会雑誌   31 ( 2 )   214 - 215   2001.12

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  • 日本人口唇・口蓋裂患者におけるマイクロサテライト多型を用いた連鎖解析

    藤田 一, 永田 昌毅, 小野 和宏, 高木 律男

    新潟歯学会雑誌   31 ( 2 )   214 - 214   2001.12

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  • 顎裂に隣接する上顎切歯の形態及び発生に関する研究 口唇口蓋裂自然発生CL/Fr系マウスについて

    早津 誠, 永田 昌毅, 小野 和宏, 飯田 明彦, 碓井 由紀子, 高木 律男, 大橋 靖

    新潟歯学会雑誌   31 ( 2 )   233 - 233   2001.12

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  • 著しい歯肉過形成を伴った骨膜下インプラント周囲炎の1例

    西原 義之, 飯田 明彦, 永田 昌毅, 福田 純一, 小野 和宏, 木村 威, 高木 律男

    日本口腔外科学会雑誌   47 ( 12 )   841 - 841   2001.12

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  • 上唇に発生した基底細胞腺癌の1例

    池田 順行, 飯田 明彦, 福田 純一, 星名 秀行, 小野 和宏, 高木 律男, 林 孝文, 朔 敬

    日本口腔科学会雑誌   50 ( 6 )   432 - 433   2001.11

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  • 口唇・口蓋裂における19q13.2領域のマイクロサテライト多型を用いた連鎖解析について

    藤田 一, 永田 昌毅, 小野 和宏, 高木 律男

    新潟医学会雑誌   115 ( 10 )   542 - 542   2001.10

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  • 骨転移障害部位における破骨性骨溶解とマクロファージ遊走(Osteoclastic Osteolysis and Macrophage Migration in Bone Metastastic Lesions)

    Amizuka Norio, Sasaki Tomoyo, Ono Kazuhiro, Ito Masahiro, Kenmotsu Shinichi, Oda Kimimitsu, Akatsu Takuhiko, Ejiri Sadakazu, Kugai Nobuo, Nagata Naokazu

    Journal of Bone and Mineral Metabolism   19 ( Suppl. )   58 - 58   2001.10

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  • Hotz床併用二段階口蓋形成手術例の顎裂部骨移植の実際とその成績

    碓井 由紀子, 小野 和宏, 高木 律男, 永田 昌毅, 飯田 明彦, 早津 誠

    日本形成外科学会会誌   21 ( 9 )   574 - 574   2001.9

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  • 下顎非対称症例のCTによる病態分析 片側過形成と片側低形成との比較

    青山 玲子, 高木 律男, 福田 純一, 鍛冶 昌孝, 星名 秀行, 小野 和宏, 阿部 哲也, 武藤 祐一

    日本顎変形症学会雑誌   11 ( 2 )   128 - 128   2001.8

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  • 下顎枝矢状分割術施行症例の長期安定性

    福田 純一, 高木 律男, 鍛冶 昌孝, 小野 和宏, 星名 秀行, 野村 裕行, 阿部 哲也, 花田 晃治

    日本顎変形症学会雑誌   11 ( 2 )   118 - 119   2001.8

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  • 口唇部腫瘤性病変に対する外科的アプローチ

    宮本 猛, 高木 律男, 小野 和宏, 星名 秀行, 飯田 明彦, 早津 誠

    日本形成外科学会会誌   21 ( 8 )   513 - 513   2001.8

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  • Hotz 床併用二段階口蓋形成手術を施行した両側性唇顎口蓋裂患者の新鮮自家骨海綿骨細片移植後の評価

    川原 のぞみ, 森田 修一, 鳥養 葉子, 石井 一裕, 花田 晃治, 小野 和宏, 飯田 明彦, 今井 信行, 早津 誠, 高木 律男, 林 孝文

    日本口蓋裂学会雑誌   26 ( 2 )   280 - 280   2001.4

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  • 新潟大学歯学部附属病院口蓋裂診療班登録患者の動向によるチームアプローチの評価について

    朝日藤 寿一, 寺田 員人, 八木 稔, 小林 正治, 小野 和宏, 飯田 明彦, 野村 章子, 石井 一裕, 田口 洋, 小林 富貴子, 田井 秀明, 寺尾 恵美子, 高木 律男, 花田 晃治

    日本口蓋裂学会雑誌   26 ( 2 )   173 - 173   2001.4

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  • LONG TERM RESULTS OF TWO STAGE PALATO-PLASTY/HOTZ'PLATE IN BCLP PATIENTS

    26 ( 2 )   180 - 180   2001.4

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  • 唇顎口蓋裂と唇顎裂を有した一卵性双生児の顎顔面形態に関する出生時から10歳迄の縦断的観察

    小野 和宏, 越知 佳奈子, 飯田 明彦, 朝日藤 寿一, 藤田 一, 石井 一裕, 早津 誠, 森田 修一, 高木 律男, 花田 晃治

    日本口蓋裂学会雑誌   26 ( 2 )   252 - 252   2001.4

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  • 両側性唇顎口蓋裂児に対するHotz床併用二段階口蓋形成手術法の顎発育に関する検討

    早津 誠, 高木 律男, 小野 和宏, 大橋 靖, 飯田 明彦, 花田 晃治, 永田 昌毅, 森田 修一, 今井 信行, 石井 一裕

    日本口蓋裂学会雑誌   26 ( 2 )   179 - 179   2001.4

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  • スカンジナビア諸国における唇顎口蓋裂患者の多施設randomized control trialに関する調査

    石井 一裕, 花田 晃治, 小野 和宏, 毛利 環, 森田 修一, 高木 律男

    日本口蓋裂学会雑誌   26 ( 2 )   170 - 170   2001.4

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  • 歯牙移植,歯科インプラントを応用した顎裂部の咬合再建

    飯田 明彦, 小野 和宏, 今井 信行, 高木 律男, 濱本 宜興, 小林 正治

    日本形成外科学会会誌   21 ( 1 )   45 - 46   2001.1

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  • Treatment of cleft lip and palet in Niigata University Dental Hosptal

    Monograph of Clinical Orthodontics   23, 1-7   2001

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  • 日本人口唇・口蓋裂患者の分子遺伝学的研究 19番染色体上の遺伝子マーカーを用いた連鎖解析

    藤田 一, 永田 昌毅, 小野 和宏, 飯田 明彦, 今井 信行, 高木 律男, 大橋 靖

    日本口腔外科学会雑誌   46 ( 13 )   877 - 877   2000.12

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  • 脳外科手術における歯科口腔外科的アプローチ

    松本 文男, 鈴木 英弘, 相馬 陽, 飯田 明彦, 小野 和宏, 高木 律男

    新潟歯学会雑誌   30 ( 2 )   274 - 274   2000.12

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  • Hotz床併用二段階口蓋形成手術例に対する顎裂部への二次的腸骨移植の成績 一段階口蓋形成手術例との比較

    碓井 由紀子, 高木 律男, 小野 和宏, 鍛冶 昌孝, 永田 昌毅, 飯田 明彦, 今井 信行, 福田 純一, 藤田 一, 早津 誠

    日本口腔外科学会雑誌   46 ( 13 )   863 - 863   2000.12

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  • 顎裂部腸骨移植術術後の患側側切歯の萠出状況について

    今井 信行, 碓井 由紀子, 高木 律男, 小野 和宏, 永田 昌毅, 飯田 明彦, 早津 誠

    日本口腔科学会雑誌   49 ( 6 )   492 - 492   2000.11

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  • 手術による機能障害の改善を見た茎状突起過長症の1例

    木村 威, 小林 龍彰, 高木 律男, 小野 和宏, 藤田 一, 田中 礼

    日本口腔科学会雑誌   49 ( 6 )   494 - 494   2000.11

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  • 最近10年間の新潟大学歯学部附属病院第二口腔外科入院患者の臨床統計学的検討

    青山 玲子, 高木 律男, 福田 純一, 中野 久, 星名 秀行, 小野 和宏, 鍛冶 昌孝, 永田 昌毅, 飯田 明彦, 今井 信行

    新潟歯学会雑誌   30 ( 1 )   101 - 101   2000.9

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  • Effects of Two-stage Palatoplasty Combined with Hotz' Plate in Bilateral Cleft Lip and Palate

    25 ( 2 )   106 - 106   2000.5

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  • 手術により機能障害の改善をみた茎状突起過長症の1例

    木村 威, 小林 龍彰, 高木 律男, 小野 和宏, 藤田 一, 田中 礼

    日本形成外科学会会誌   20 ( 5 )   335 - 335   2000.5

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  • 両側性口唇裂及び口蓋裂におけるHotzプレート併用2期口蓋裂形成術の効果

    アルチビアデス・シルベラ, 石井 一裕, 新井 透, 森田 修一, 小野 和宏, 花田 晃治, 高木 律男

    日本口蓋裂学会雑誌   25 ( 2 )   106 - 106   2000.5

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  • 歯牙移植,歯科インプラントを応用した顎裂部の咬合再建

    飯田 明彦, 小野 和宏, 今井 信行, 高木 律男, 濱本 宜興, 小林 正治, 朝日藤 寿一, 毛利 環, 田中 みか子, 櫻井 直樹

    日本口蓋裂学会雑誌   25 ( 2 )   94 - 94   2000.5

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  • Hotz床併用二段階口蓋形成手術法施行患者の新鮮自家腸骨海綿骨細片移植術の評価 X線CTを用いて

    鳥養 葉子, 森田 修一, 石井 一裕, 花田 晃治, 小野 和宏, 今井 信行, 高木 律男, 林 孝文

    日本口蓋裂学会雑誌   25 ( 2 )   203 - 203   2000.5

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  • Furlow法を施行した口蓋裂児の混合歯列前期における顎顔面形態について

    小野 和宏, 高木 律男, 飯田 明彦, 今井 信行, 朝日藤 寿一, 石井 一裕, 森田 修一, 花田 晃治

    日本口蓋裂学会雑誌   25 ( 2 )   114 - 114   2000.5

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  • Hotz床併用2段階口蓋形成術の矯正治療に及ぼす効果について

    朝日藤 寿一, 石井 一裕, 森田 修一, 花田 晃治, 小野 和宏, 高木 律男

    日本口蓋裂学会雑誌   25 ( 2 )   107 - 107   2000.5

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  • Hotz床併用二段階口蓋形成手術法を施行した片側性唇顎口蓋裂児の顎発育

    小野 和宏, 飯田 明彦, 今井 信行, 高木 律男, 新井 透, 石井 一裕, 朝日藤 寿一, 森田 修一, 花田 晃治, 大橋 靖

    日本口蓋裂学会雑誌   25 ( 2 )   89 - 89   2000.5

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  • 矯正治療への自家歯牙移植の応用、歯の移動のための移植の問題点(共著)

    アドバンス自家歯牙移植、適応症の拡大(クインテッセンス出版)   34 - 47   2000

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  • Oropharynx carcinoma with lateral retropharyngeal lymph node metastasis successfully controlled by thermo-chemo-radiotherapy : report of a case

    Hideyuki Hoshina, Tatsuo Inoue, Hiroshi Tsurumaki

    Niigata Dent. J.   30 ( 1 )   43 - 47   2000

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  • Effects of Two-Stage Palatoplasty Combined with Hotz's Plate on Maxillary Growth in Unilateral Cleft Lip and Palate-Comparison of Permanent Dentition of Patients Treated by One-Stage Palatoplosty and Noncleft Normal Subjects-

    ONO Kazuhiro, IIDA Akihiko, IMAI Nobuyuki, FUKUDA Jun-ichi, HAYATSU Makoto, TAKAGI Ritsuo, ARAI Toru, ASAHITO Toshikazu, ISHII Kazuhiro, MORITA Schuichi, HANADA Kooji, OHASHI Yasushi

    J. Jpn. Cleft Palate Assoc.   25 ( 1 )   36 - 44   2000

  • Effects of Hotz' Plate-Based Two-Stage Palatoplasty in Unilateral Cleft Lip and Palate-A Comparative Study of Subjects Treated with One-Stage Palatoplasty and Normal Subjects-(共著)

    ISHII Kazuhiro, ARAI Toru, SAITO Isao, MORITA Shuichi, HANADA Kooji, ONO Kazuhiro, TAKAGI Ritsuo

    Orthodontic Waves   59 ( 6 )   402 - 406   2000

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    PURPOSE ; The purpose of this study was to investigate effects of two-stage palatoplasty combined with Hotz' plate on craniofacial development of mixed dentition patients with complete unilateral cleft lip and palate (UCLP). MATERIALS AND METHODS : The subjects selected for this study were 42 Japanese boys, 9 to 11 years old, from following three different groups : Group A (two-stage group) consisting of 15 UCLP subjects whose cleft palates were closed with two-stage palatoplasty combined with Hotz' plate (soft palatal closure at 18 months and hard palatal closure at 6 years) ; Group B (one-stage group) consisting of 14 subjects whose cleft palates were closed with one-stage palatoplasty within 2 years of age ; Group C (control group) consisting of 13 subjects who had non-cleft Class I occlusion. Lateral headfilms of each group (mean age=9.8, 10.0, 10.3 years for group A, B, C respectively) were examined. Cephalometric measurements including 14 angles, 7 distances, and 2 ratios were obtained and the findings from three groups were compared with each other by Fisher's PLSD (p<0.05). RESULTS : Measurements in which both Group A (two-stage group) and Group C (control group) showed significantly larger values than Group B (one-stage group) and there was no significant difference between Group A and C were SNA, ANB, and maxillary length. Measurements in which Group C showed significantly larger values than Group B and there was no significant difference between Group A and C were anterior upper facial height (AUFH) and ratio of AUFH to anterior lower facial height. Measurement in which both cleft groups (Group A and B) showed significantly smaller values than Group C (control group) and there was no significant difference between Group A and B was U1 to S-N in the non-cleft side. CONCLUSION : The findings in this study showed that craniofacial development up to mixed dentition in UCLP subjects with two-stage palatoplasty combined with Hotz's plate was better than that in UCLP subjects with one-stage palatal closure, and relatively similar to that of subjects with normal occlusion, indicating that this procedure for palatal closure could be advantageous for craniofacial development.

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    Other Link: https://projects.repo.nii.ac.jp/?action=repository_uri&item_id=198407

  • 5-FU Concentration in the Serum and the Tumor Tissue after Administration of UFT 200mg/day to Patients over 80 Years of Age with Oral Cancer.

    Jpn. J. Cancer Chemother.   27 ( 10 )   1527 - 1532   2000

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  • Application of Tooth Auto-transplantation in the Orthodontic Field Orthodontic Cases with Surgical Repositioning

    ( 34 )   47   2000

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  • 新潟大学歯学部附属病院口蓋裂診療班運営委員会の登録患者の動向および評価について その2 平成11年度 新潟歯学会 第1回例会

    寺田員人, 八木稔, 岡本明, 久保田健彦, 小林正治, 中野久, 小野和宏, 高木律男, 花田晃治

    新潟歯学会雑誌   29 ( 2 )   205   1999.12

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  • 片側性唇顎口蓋裂児におけるHotz床併用2段階口蓋形成 手術法が顎顔面成長に及ぼす影響について

    新井 透, 石井 一裕, 森田 修一, 花田 晃治, 小野 和宏, 高木 律男

    新潟歯学会雑誌   29 ( 2 )   216 - 217   1999.12

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  • 二段階口蓋形成手術法と顎発育 健常児及び一段階法施行例との永久歯列弓形態の比較

    小野 和宏, 飯田 明彦, 福田 純一, 今井 信行, 早津 誠, 高木 律男, 大橋 靖, 新井 透, 朝日藤 寿一, 石井 一裕

    日本口蓋裂学会雑誌   24 ( 2 )   147 - 147   1999.6

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  • 片側性唇顎口蓋裂児におけるHotz床併用2段階口蓋形成手術法が顎顔面成長に及ぼす影響について(第2報)

    新井 透, 石井 一裕, 森田 修一, 花田 晃治, 小野 和宏, 高木 律男

    日本口蓋裂学会雑誌   24 ( 2 )   187 - 187   1999.6

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  • 顎裂に隣接する上顎切歯の萠出状態の評価 Hotz床併用二段階口蓋形成手術症例について

    早津 誠, 中野 久, 小野 和宏, 永田 昌毅, 飯田 明彦, 今井 信行, 碓井 由紀子, 児玉 泰光, 高木 律男, 大橋 靖

    日本口蓋裂学会雑誌   24 ( 2 )   265 - 265   1999.6

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  • 二段階法における硬口蓋閉鎖手術の術後評価 口蓋感覚について

    飯田 明彦, 高木 律男, 小野 和宏, 磯野 信策, 今井 信行, 早津 誠, 碓井 由紀子, 児玉 泰光, 大橋 靖

    日本口蓋裂学会雑誌   24 ( 2 )   249 - 249   1999.6

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  • 鼻咽腔閉鎖機能と口唇閉鎖機能との関連性 Secondary Furlow法の術前術後の口輪筋筋活動

    今井 信行, 高木 律男, 中野 久, 小野 和宏, 飯田 明彦, 早津 誠, 児玉 泰光, 磯野 信策

    日本口蓋裂学会雑誌   24 ( 2 )   240 - 240   1999.6

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  • Hotz床併用二段階口蓋形成手術法で治療した片側性唇顎口蓋裂児の混合歯列期における歯列弓形態について

    小野 和宏, 飯田 明彦, 高木 律男, 朝日藤 寿一, 森田 修一, 花田 晃治

    日本形成外科学会会誌   19 ( 4 )   246 - 246   1999.4

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  • 移植歯の矯正移動について(共著)

    臨床家のための矯正YEAR Book'99(クインテッセンス出版)   126 - 132   1999

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  • Orthodontic Movement of Auto-transplanted Tooth

    126 - 132   1999

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  • 染色体核型異常を有する口唇口蓋裂患者の臨床統計的観察

    藤田 一, 小野 和宏, 飯田 明彦, 今井 信行, 神成 庸二, 高木 律男, 大橋 靖

    日本口腔外科学会雑誌   44 ( 13 )   1246 - 1246   1998.12

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  • 唇顎口蓋裂を伴ったCHARGE associationの2例

    松本 文男, 大橋 靖, 神成 庸二, 今井 信行, 小野 和宏, 高木 律男

    日本口腔科学会雑誌   47 ( 5 )   647 - 648   1998.12

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  • 80歳以上の高齢口腔癌患者に対するUFT200mg投与の有用性に関する検討

    飯田 明彦, 大橋 靖, 高木 律男, 星名 秀行, 小野 和宏, 鍛冶 昌孝, 服部 幸男, 福田 純一, 長島 克弘, 宮浦 靖司

    日本口腔外科学会雑誌   44 ( 13 )   1198 - 1198   1998.12

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  • 最近14年間における第二口腔外科外来患者の臨床統計的観察

    阿部 哲也, 大橋 靖, 高木 律男, 星名 秀行, 小野 和宏, 鍛冶 昌孝, 飯田 明彦, 今井 信行, 服部 幸男, 安島 久雄

    新潟歯学会雑誌   28 ( 1 )   93 - 94   1998.7

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  • Clinico-statistical Observation of Outpatients During Last 14 Years in Our Clinic

    Niigata Dent. J.   28 ( 2 )   9 - 17   1998

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  • Effects of two-stage palatoplasty combined with Hotz's plate

    T Arai, K Ishii, S Kaloust, T Asahito, Saito, I, K Yamada, S Morita, K Ono, K Hanada, Y Ohashi

    JOURNAL OF DENTAL RESEARCH   77   889 - 889   1998

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  • A case-control study on cleft lip and/or palate associated with maternal factors during pregnancy

    Niigata Dent. J.   28 ( 2 )   1 - 8   1998

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  • Team Approach in a Clinical Case of Cleft Lip and Palete Complicated with Partial Anodontia(共著)

    J. Jpn. Cleft Palate Assoc.   23   1 - 12   1998

  • Hard palate closure in two-stage palatoplasty(共著)

    IIDA Akihiko, OHASHI Yasushi, TAKAGI Ritsuo, ONO Kazuhiro, IMAI Nobuyuki, KANNARI Yoji, HAYATSU Makoto

    J. Jpn. Cleft Palate Assoc.   23 ( 2 )   68 - 74   1998

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    Language:Japanese   Publisher:Japanese Cleft Palate Association  

    The intraoperative and postoperative results of hard palate closure were investigated in the case of two-stage palatoplasty in our clinic. Comparative analyses have been made between the results of the cases operated only by using vomer flap (vomer flap group, n=76)and those of the cases operated by using vomer and palatal flaps (vomer+palatal flap group, n=16).<BR>The results were as follows:<BR>1. The blood loss of the vomer flap group (mean: 42.4 g) is significantly less than that of the vomer+palatal flap group (mean: 103.6 g).<BR>2. Only 10 cases (10.9 %) had postoperative fistula. The ratio of fistula formation was not significantly different between the two groups. There was no case with large fistula that causes critical dysfunction such as speech difficulties.<BR>3. Raw surface made by operation have been covered by TERUDERMIS(Artificial dermis made of atelocollagen). There was no case with severe operation scar.<BR>4. It was considered that the usefulness of two-stage palatoplasty can be enhanced by the operation using vomer flap alone, which causes less surgical damage.

    DOI: 10.11224/cleftpalate1976.23.2_68

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    Other Link: http://search.jamas.or.jp/link/ui/1998224371

  • 7)最近の口唇口蓋裂治療 : 当科における出生直後からの治療体系について(I. 一般演題, 第3回新潟周産母子研究会)

    中野 久, 大橋 靖, 小野 和宏, 永田 昌毅, 飯田 明彦, 今井 信行, 神成 庸二, 早津 誠, 碓井 由紀子

    新潟医学会雑誌   111 ( 8 )   532 - 532   1997.8

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    Language:Japanese   Publisher:新潟医学会  

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    Other Link: http://search.jamas.or.jp/link/ui/1998158751

  • Clinical Evaluation of the Intra-articular Injection of Sodium Hyaluronate for the Patients Suffering from Internal Derangement with Persistent Pain(共著)

    Niigata Dent. J.   27 ( 2 )   153 - 159   1997

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  • 1994年から1995年にかけての1年間に出生した日本人303,738名中の口唇・口蓋裂児発生調査(共著)

    文部省科学研究総合研究A(課題番号06304042)報告書   1996

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  • CRANIOSYNOSTOSIS WITH JOINT CONTRACTURES, EAR DEFORMITY, CLEFT-PALATE, SCOLIOSIS, AND OTHER FEATURES

    A IIDA, Y OHASHI, K ONO, N IMAI, Y KANNARI

    CLEFT PALATE-CRANIOFACIAL JOURNAL   32 ( 6 )   489 - 493   1995.11

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:DECKER PERIODICALS INC  

    A case of craniosynostosis with joint contractures, ear deformity cleft palate, scoliosis, and many other features is presented. The patient's skull was round with craniosynostosis of the coronal suture. The fingers were slender and long; the finger joints were contracted. Trismus was also present. Contracture of the temporomandibular joint was suspected. The helices were flat, antihelices were minimal, and the ears protruded. Furthermore, the facial and cranial features of this patient included mild hypertelorism, ocular proptosis, short pens nasi, flat radix nasi, mild retrognathia, and small oral fissure. In the oral cavity, a relatively wide cleft extended from the soft palate to the uvula. A frontal chest radiograph revealed a mild scoliosis. Differential diagnoses are discussed in reported syndromes with craniosynostosis.

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  • A Case of Tetanus doubted as TMD.

    Niigata Dental Journal   24 ( 2 )   219 - 223   1994

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  • PARTIAL MONOSOMY-5P AND PARTIAL TRISOMY-5Q DUE TO PATERNAL PERICENTRIC-INVERSION OF CHROMOSOME-5

    K ONO, Y OHASHI, H NAKANO, H TOGASHI, Y KANNARI, S ISONO

    JAPANESE JOURNAL OF HUMAN GENETICS   38 ( 3 )   319 - 328   1993.9

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:TOKYO MEDICAL DENTAL UNIV  

    A male infant with partial monosomy 5p and partial trisomy 5q due to paternal pericentric inversion of chromosome 5 (46,XY,rec(5), dup q,inv(5)(p15.1q35.1)pat) is reported together with the oral findings. The phenotype was chiefly the cri-du-chat syndrome. Severe retardation of mental and motor development, microencephaly, cardiac malformation, crying and facial appearance unique to the cri-du-chat syndrome were observed. Perioral and intraoral findings included thin upper lip, down-turning corners of mouth, micrognathia, shallow palate, and cleft of soft palate. Anterior deciduous teeth were small and canine deciduous teeth were conic. The row of deciduous teeth showed a flat arch-like shape that was very wide but short in length. No abnormality was noted in the number of deciduous teeth or the timing of eruption.

    DOI: 10.1007/BF01874142

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  • Vasomotor Reflex Induced by Periodontal Stmulation in Palatal Mucosa of Rat

    Niigata dental Journal   23 ( 2 )   25 - 36   1993

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  • 歯科疾患の疫学 口唇裂口蓋裂

    小野 和宏, 大橋 靖

    歯科ジャーナル   36 ( 5 )   731 - 742   1992.11

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    Language:Japanese   Publisher:(株)アークメディア  

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  • 口腔症候群(13) Apert症候群

    小野 和宏, 大橋 靖

    DENTAL DIAMOND   17 ( 10 )   64 - 65   1992.8

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    Language:Japanese   Publisher:(株)デンタルダイヤモンド社  

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Works

  • Randomized Control Trial of Primary Surgery on UCLP

    2002
    -
    2005

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  • 片側性唇顎口蓋裂患者に関する多施設比較研究―レトロスペクティーブ・スタディからランダマイズド・コントロール・トライアルへ―

    2002
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    2005

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  • Transplantation and Cryoreseration of Teeth

    2001
    -
    2003

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  • 歯の移植と歯の凍結保存

    2001
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    2003

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Research Projects

  • A Study of Competency Formation and Assessment: Focusing on Integration, Subject-Specificity, and Agency

    Grant number:22H00965

    2022.4 - 2026.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (B)

    Awarding organization:Japan Society for the Promotion of Science

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    Grant amount:\16640000 ( Direct Cost: \12800000 、 Indirect Cost:\3840000 )

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  • Understanding fundamental masticatory function by evaluation of physiological and food science approaches

    Grant number:22K10073

    2022.4 - 2025.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

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    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

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  • Fostering and assessing knowledge and skills focusing on the relation between subject-specificity and generality

    Grant number:18H00975

    2018.4 - 2021.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (B)

    Awarding organization:Japan Society for the Promotion of Science

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    Grant amount:\8840000 ( Direct Cost: \6800000 、 Indirect Cost:\2040000 )

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  • Age related change in ingestion related function and anatomy and its relationship

    Grant number:17K12041

    2017.4 - 2020.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    Ono Kazuhiro

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    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

    The present study performed simultaneous recordings of hyoid EMG, tongue pressure and videofluoroscopic images to clarify the relationship between the lingual motor function and hyoid and laryngeal movements.
    Tongue pressure at anterior portion was significantly higher than that at posterior portion. Hyoid EMG activity was significantly higher at the anterior tongue pressure generation than that at the posterior tongue pressure generation. During 10 sec sustained tongue pressure measurement, EMG activity increased and the power frequency of EMG burst decreased. There results suggest that the hyoid muscles can compensate for the fatigue of tongue muscles during tongue pressure measurement. Further, hyolaryngeal movements were larger during the posterior tongue pressure generation than those during the anterior tongue pressure generation.

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  • Proof of competency on the dental clinical training with web combined e-portfolio

    Grant number:17K01075

    2017.4 - 2020.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    Oda Yohei

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    Grant amount:\3770000 ( Direct Cost: \2900000 、 Indirect Cost:\870000 )

    We developed and applied the web combined e-portfolio system for the dental clinical training in Niigata University as "the system which could evaluated and demonstrate the clinical skill of the student appropriately". As a result, it was able to demonstrate that this system could improve the general ability of the student by the careful instruction, evaluation with the portfolio, repetition of the feedback.

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  • Development and expansion of performance assessments for advancing student competences

    Grant number:15H03473

    2015.4 - 2018.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (B)

    Awarding organization:Japan Society for the Promotion of Science

    Matsushita Kayo

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    Grant amount:\10530000 ( Direct Cost: \8100000 、 Indirect Cost:\2430000 )

    Adopting the Faculty of Dentistry at Niigata University and the Department of Physical Therapy at Aino University as our main fields of practical study, we redesigned and implemented performance assessments --"Modified Triple Jump" and "Deep OSCE-R" -- in order to evaluate student competences (e.g., problem solving, basic clinical competences). In addition, through integrating direct and indirect assessments, we illustrated both qualitatively and quantitatively that those performance assessments also promoted students' deep active learning and fostered their competences.
    Furthermore, we developed Pivotal Embedded Performance Assessment (PEPA) as a new method of utilizing performance assessments as learning outcomes assessments at program level as well as course level.

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  • Development and employment of web combined e-portfolio for dental clinical training

    Grant number:26350270

    2014.4 - 2017.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    Oda Yohei

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    Grant amount:\2470000 ( Direct Cost: \1900000 、 Indirect Cost:\570000 )

    Faculty members of dental colleges have recently tried to improve the technical education and have strived to enhance their clinical clerkship systems.
    A portfolio has been known as to be a useful formative evaluation tool, and it can chronologically record the cumulative learning process. Therefore, a web-based e-portfolio system including an assessment rubric for students and instructors was invented and applied to the clinical clerkship. The general clinical skill evaluation level that was assessed and marked on the system by the instructors had a tendency of gradually advancing with the progress of the clinical clerkship term, and it was suggested that the clinical skills of the students improved with their own clinical experiences. The web-based e-portfolio system on the clinical clerkship was considered to be a meaningful tool for reviewing the performance of students and facilitating effective training by the instructors.

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  • Relation between hyo-laryngeal position and swallowing function

    Grant number:25462992

    2013.4 - 2016.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    Ono Kazuhiro, INOUE Makoto, MAGARA Jin

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    Grant amount:\5070000 ( Direct Cost: \3900000 、 Indirect Cost:\1170000 )

    Laryngoptosis or uncoordinated movement of hyoid and larynx in functions in elderly people and dysphagic patients may cause impaired transport of bolus and residues after swallowing, which leads to bolus penetration or aspiration. The present study was undertaken to validate the relationship between hyoid movement or tongue pressure production and swallowing function by evaluating spatial and temporal hyoid excursion, hyoid position and bolus transmission as well as voluntary generation of anterior and posterior tongue pressure in healthy and dysphagic humans.

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  • Building "University Education Commons" for the Advancement of Higher Education Improvement and the Promotion of Educational Inovation

    Grant number:25242017

    2013.4 - 2016.3

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (A)

    Awarding organization:Japan Society for the Promotion of Science

    Iiyoshi Toru, KAJITA Shoji, SAKAI Hiroyuki, MIZOKAMI Shinichi, KITA Hajime, ONO Kazuhiro, OKABE Yoichi, OZAWA Shigeto, TOSA Naoko, TAJINO Akira, TAKAHASHI Sachi, SHIGETA Katsusuke, OTSUKA Yusaku, MATSUSHITA Kayo, SUZUKI Shoko, TAGUCHI Mana, MURAKAMI Masayuki, UCHIMURA Hiroshi, KATO Kyoko, TSUTSUI Yoichi, AMANO Kazuya, KOMAI Shoji, SUZUKI Atsushi, SAKATA Nobuhiro, INABA Rieko, KAMIYA Kenichi, MURAKAMI Yuko, TANAKA Ikko, OKAMOTO Masako, KIMURA Syuhei, TSUJI Yasuhiko, OKUBO Mami, OGO Kazutoshi, KAMEDA Masumi, TATSUSHIMA Yumi, MAIYA Kiyoshi, MIZUNO Kunitaro, TANAKA Hiroaki, YANO Kojiro, NARUSE Takashi, SUGIMOTO Ayumi, SAITO Hiromichi, HAGA Akira, WATANABE Michiru, MIURA Kazumi, MICHIYUKI Toshiya, TSUBUKI Tatsuya, SAKURAI Noriko, TSUNEMI Sachi, SUZUKI Yoshinobu

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    Grant amount:\44460000 ( Direct Cost: \34200000 、 Indirect Cost:\10260000 )

    Through this research, the “University Education Commons,” an online system that serves as an open knowledge platform, was developed to support sharing educational knowledge and building communities of practice for systematic and sustainable improvement of higher education. By examining a conceptual model for using multimedia ePortfolio to build and share practical educational knowledge, the effectiveness of the innovative methods and the support system that enable building and sharing educational practical knowledge across different local educational contexts that depend on particular disciplines, courses, and instructors, was empirically proven.

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  • Involvement of vascular elements in formation of articular cavity in temporomandibular joint

    Grant number:22592207

    2010 - 2012

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    ONO Kazuhiro, MAEDA Takeyasu, SUZUKI Akiko

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    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

    The upper articular cavity formation had begun in advance of the lower cavitation. In the area of the prospective upper articular cavity, the phagocytosis by ED1-positive macrophages expanded the intercellular spaces of mesenchymal cells to form the cleft between the temporal bone and articular disk at embryonic day 18. On the other hand, the CD31-positive endothelial cells were restricted to the lower cavity-forming area at embryonic day 19 to spread out the tissue between mandibular condylar and articular disk, and diminished thereafter. The appearance of ED1-reactive macrophages and temporal vascularization play crucial roles in the upper and lower articular cavity formation, respectively.

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  • 顎関節関節腔形成には血管進入が不可欠である

    Grant number:16659498

    2004 - 2005

    System name:科学研究費助成事業

    Research category:萌芽研究

    Awarding organization:日本学術振興会

    小野 和宏, 高木 律男, 前田 健康, 井上 佳世子, 河野 芳朗

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    Grant amount:\3200000 ( Direct Cost: \3200000 )

    様々な仮説が提唱されている顎関節腔形成機序において、血管進入との関係を明らかにした報告はほとんど存在しない。本研究では、ラットの関節腔形成における血管新生とそれに伴う組織破壊酵素の関与を明らかにするために、血管内皮細胞、マクロファージの動態に着目し、それぞれのマーカーであるCD31,RECA-1およびED1を用いた免疫組織化学的手法にて検索し、以下の結果を得た。
    ラット顎関節腔は、上関節腔が胎生21日から生後1日で形成され、続いて下関節腔形成が生後1日から3日に起こる。側頭骨、下顎頭、関節円板原基が出現し、関節腔形成領域が明らかになる胎生19日から21日にかけて、上関節腔形成予定部位の間葉組織内に多数のED1陽性マクロファージが侵入する。また、下顎頭表層に沿って、CD31,RECA-1陽性血管内皮細胞の配列と毛細血管の侵入を認めた。上関節腔形成が開始する胎生21日以降、形成途中の腔周囲および円板内にマクロファージが散在し、生後1日の上関節腔完成後は、滑膜内に広く存在し、一部は表層細胞層へも配列していた。一方、胎生21日から下関節腔形成開始までは、下顎頭表層に配列していた毛細血管はそれと直交するように下顎頭内へも深く走行していたが、下関節腔形成の進行に伴ってこれらの血管内皮細胞は消失し、生後3日には滑膜内と下顎頭表層の血管のみにCD31陽性反応を認めた。関節腔形成におけるアポトーシスの関与をTUNEL法にて検討したが、上下とも陽性反応は認められず、積極的な関与は起こらないと考えられた。
    以上より、顎関節関節腔形成は、時期、機序において上下で異なることが明らかとなった。上関節腔形成は、マクロファージの侵入により間葉細胞間が拡大して裂隙が形成され、下関節腔形成では、血管内皮細胞の侵入と血管腔の形成により円板と下顎頭の間が押し広げられることにより腔が形成されることが示唆された。

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  • Intercenter comparison studies for patients with unilateral cleft lip and palate in Japan

    Grant number:14370692

    2002 - 2005

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (B)

    Awarding organization:Japan Society for the Promotion of Science

    MORITA Shuichi, ASAHITO Toshikazu, SAITO Isao, ONO Kazuhiro, SUSAMI Takahumi, KOCHI Syoko

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    Grant amount:\6800000 ( Direct Cost: \6800000 )

    Objective : The aim of this study is to establish the effective and treatment of unilateral cleft lip and palate.
    Subjects and Methods : 95 unilateral cleft lip and palate cases bone in 1992-1994, and treated at 6 cleft lip and palate centers (Niigata University, Tohoku University, Tokyo University, Showa University, Aichi-Gakuin University and Osaka University.) We examined 5 factors (1.protocol,2.lateral cephalograms, 3.Study models.4.Lip and Nose form,5.Speech therapy)
    Results : Six centers were different about treatment protocol entirely, and each centers treated it with an original treatment system. In addition, we found some tendency about operation system and cases, and analysis was able to examine various influence factors from many aspects. However, when we considered bias at the time of document collection, it seemed that it was necessary to perform interpretation about relevance with presence of orthognatic treatment, time of chiloplasty, palatoplasty, and timing of starting orthodontic treatment, unevenness off the number of the cases.

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  • Randomized Control Trial of Primary Surgery on CLP

    2001 - 2005

    System name:Grant-in-Aid for Scientific Research

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    Grant type:Competitive

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  • 口唇口蓋裂患者に関する多施設比較研究

    2001 - 2005

    System name:科学研究費補助金

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    Grant type:Competitive

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  • Study on three-dimensional effects of Hotz plate-based two-stage palatoplasty on mid-facial development

    Grant number:13672142

    2001 - 2002

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    TERADA Kazuto, ASAHITO Toshikazu, ONO Kazuhiro

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    Grant amount:\3900000 ( Direct Cost: \3900000 )

    The purpose of this study was to investigate the effects of two-stage palatoplasty combined with Hotz' plate on sagittal mid-facial development in complete unilateral cleft lip and palate (UCLP) individuals.
    Materials and Methods:
    The subjects selected for this study were 72 Japanese individuals (age: 9-19 years) divided into Group A (two-stage palatoplasty) consisting of 24 UCLP subjects (12 females and 12 males), Group B (one-stage palatoplasty) consisting of 24 UCLP subjects (12 females and 12 males), Group C (control group) consisting of 24 non cleft subject (12 females and 12 males) who had Class I skeletal relation. The investigation of soft tissue morphology was carried out using a three-dimensional surface scanner (VIVID 700, Minolta. co) and an analyzing soft ware. The 9 corresponding facial measurement points were obtained by intersection of the following planes; 3 vertical planes parallel to mid-sagittal planes through entocanthion, pupulare and ectocanthion, 3 horizontal planes parallel to Frankfort plane through ear rod, alare and mid-point ear rod and alare, respectively. Mid-facial sagittal growth was determined by evaluating the difference of z-coordinates values of 9 corresponding facial measurement points between both sides for each cleft group and between right and left sides for control group. Both side in the cleft group and in the control group were evaluated by student's t-test. The differences among the three groups were statistically compared by ANOVA.
    Results:
    The chi-square test using scores gained by each group, revealed significant difference among three groups. Mid-facial sagittal growth was similar on cleft side and non-cleft side or right and left side in two-stage group and control group. Mid facial sagittal growth on non-cleft side was bigger than cleft side in one-stage group.
    Conclusion:
    Cleft patients, who undertook two-stage palatoplasty showed a better sagittal mid-facial development than the one with one-stage palatal closure.

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  • 国際規格による唇顎口蓋裂患者顎顔面発育の多施設比較研究のための企画調査

    Grant number:12897019

    2000

    System name:科学研究費助成事業

    Research category:基盤研究(C)

    Awarding organization:日本学術振興会

    花田 晃治, 小林 正治, 森田 修一, 石井 一裕, 小野 和宏, 高木 律男

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    Grant amount:\3100000 ( Direct Cost: \3100000 )

    今回の企画調査では、Oslo(Norway)およびGoteborg(Sweden)のクレフトチームを訪問しスカンジナビア諸国の多施設比較研究について調査するとともに、その一環としてProf.Semb(University of Oslo,Norway)とProf.Friede(Gothenberg University,Sweden)を招聘し、東京、新潟、名古屋でスカンジナビアの口蓋裂患者管理と多施設比較研究についての講演会を開催した。
    その結果、1991年に行われたretrospectiveな多施設間研究の問題点、またより信頼できるevidence baseを求め1997年から行われている多施設比較randomized control trialsの背景、詳細な実施方法、protocol等について明らかにすることができ、さらにその重要性を多くの関係者に伝えることができた。このrandomized trialsでは、10カ所のcleft teamで3つのグループをつくり、各グループとも無作為に振り分けられた患者の約半数を共通の術式で管理するとともに、残りの半数をグループで異なった術式で管理していた。すなわち、このtrialでは4つの術式についてprospectiveに検討していた。
    唇顎口蓋裂患者の治療は、出生後から成人までの長期管理が必要とされる。さらに、口蓋閉鎖の時期や術式が、その後の顎顔面成長に大きな影響を与えるのみならず、発音などの機能回復にも強く影響することから、国内各施設がそれぞれに工夫をこらして術式の改良を試み、それぞれの立場で成果をあげている。しかし、その成果の評価も各施設内で行われるにとどまり、改良にも限界があるように思われる。今後、さらなる向上をはかるには各施設が治療経過や結果をprospectiveに比較検討し、その結果を治療システムにフィードバックする必要があると思われる。

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  • Molecular analysis of nonsyndromic cleft lip and/or palate

    1997 - 2000

    System name:Grant-in-Aid for Scientific Research

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    Grant type:Competitive

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  • 口唇口蓋裂の遺伝学的研究 -分子生物学的分析-

    1997 - 2000

    System name:科学研究費補助金

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    Grant type:Competitive

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  • Achievement of Velopharyngeal Function in the Children with Cleft Lip and Palate -Relationship Velopharyngeal Function with Speech DevelopmentィイD1ィエD1

    Grant number:09672040

    1997 - 1999

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    NAKANO Hisashi, ISONO Shinsaku, ONO Kazuhiro

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    Grant amount:\3400000 ( Direct Cost: \3400000 )

    It was evaluated about velopharyngeal function and speech development in the children with cleft lip and palate following Furlow's veloplasty
    Research subject and method : Subject ; 25patients with cleft lip and palate (18UCLP, 7BCLP) and 23patients with isolated cleft palate, who are performed Fulow's veloplasty from January, 1992 by December, 1998. Velopharyngeal function and articulation development were evaluated at the age of two years, three years, four years, and five years. Velopharyngeal function was examined by velar movement, blowing examination, videofluoloscopy, ultrasonnography, fiberscopy, corresponding to the age. It was evaluated synthetically, and a decision made a unction three steps of favorably, border line, unfavorably. The evaluation of the speech development was went by the existence of nasality, nasogram, the compensatory articulation, the frequency analysis by the sound analytic device (multi-speech).
    Results and Discussion : Evaluation of velopharungeal function ; In CLAP, though there were many border line cases with 68% at the time of 2 years old, favorable cases increased with 52% at the time of 3 years old, and it was 77% in 4 years old and 83% in 5 years old. In CP, border line cases were 65%, it shows a tendency to make function acquisition early at the time of 2 years old, but favorable cases were 65% at 4 years old, 87% at 5 years old. Speech evaluation ; It was compared in the acquired time of velopharyngeal function in CLAP, and the tendency that co m pensatory articulationun remained easily till late was recognized. The acquired tendency of normal articulation which was suitable for the acquired time of the velopharyngeal function was suggested with CP child.
    Relationship of the acquisition of the velopharyngeal function and the speech development : At the time of three years old, with the all border line cases, they have articulation with glottal stop, palatalizafion, nasal articulation, incomplete articulation development after that. It thought about this with the difficulty by obviously velopharyngeal function acquisition's being delayed. And the participation of velopharyngeal incompetence was suggested as for the palatalization as well.

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  • A Study on Production of a New Model of Cleft Lip and Cleft Palate by Fetal Manipulation

    Grant number:07557370

    1995 - 1996

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for Scientific Research (A)

    Awarding organization:Japan Society for the Promotion of Science

    OHASHI Yasushi, KANNARI Youji, IIDA Akihiko, NAGATA Masaki, ONO Kazahiro, NAKANO Hisashi

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    Grant amount:\1000000 ( Direct Cost: \1000000 )

    We carried out experiments on the production of an animal model for clarification of the developmental factors of craniofacial malformations including cleft lip and palate and the mode of progression of facial deformations associated with malformations during the fetal period.
    1. Exo utero surgery was performed in mouse fetuses. At a fetal age of 10-12 days when the basic morphology of the fetal face is completed, the face primodium was injured by electrocoagulation using fine glass needle electrodes or argon laser photocoagulation, inducing facial deformations during subsequent growth. By these procedures, we searched for a fetal manipulation method to clarify the mode of facial growth from the formation of the mouse embryonic facial projection to birth.
    2. Exo utero fetuses in which the face was directly invaded via the decidua, yolk sac, and the aminon at the age of 11-12 days subsequently showed growth similar to that in the surrounding intrauterine fetuses.
    3. Of exo utero fetuses in which the face was invaded by electrocoagulation using fine glass needle electrodes, about 50% survived to a fetal age of 12 days and showed asymmetrical face and secondary palatal tissue defects in the deep area.
    4. Of exo utero fetuses in which the face was invaded by argon laser photocoagulation on 11 days of gestation, 20% survived to the term and primarily showed asymmetrical facial morphology due to tissue difects in the facial surface layr.
    5. The malformation characterized by maxillary asymmetrical growth that occurred in a CL/Fr mouse colony was established as a genetic substrain.
    These results suggest that congenital craniofacial deformations can be induced by fetal face manipulation. This study may provide useful data for the establishment of experimental systems.

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  • The neurophysiological study about the control mechanism of the velopharyngeal function

    Grant number:06404071

    1994 - 1995

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for General Scientific Research (A)

    Awarding organization:Japan Society for the Promotion of Science

    OHASHI Yasushi, ONO Kazuhiro, ISONO Shinsaku, NAKANO Hisashi

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    Grant amount:\10000000 ( Direct Cost: \10000000 )

    For the purpose of the neurophysiological analysis of the velopharyngeal function, the data collecting analysis device (BRC ; Maclab8) and the polygrapH system (NIHON KOHDEN : RM-6000) were purchased as the equipment that was written in the grant application in 1994 and 1995. Experiments were performed in cats. The cats were anesthetized with halothane and decerebrated. A bipolar electrode was inserted into the levator veli palatini muscle which was a major muscle elevating the soft palate.
    In 1994, the innoxious mechanical stimulation was applied to the tongue dorsum. Excitatory or inhibitory response was elicited in the levator veli palatini muscle by pressure stimulation to the tongue dorsum. Excitatory reflexes were elicited under low level background activity (BGA). The excitatory effect decreased with increase of BGA,the inhibitory effect was increased . Reversal levels were calculated from BGA-response curves.As stimulation sites were changed from anterior to posterior of the oral cavity, the reversal level increased. This result indicated that the excitatory reflex was easily elicited from the posterior part and the inhibitory reflex was easily elicited from the anterior part of the oral cavity.
    We continued animal experiments in 1995. Assumed the contact style of the tongue to the palate at the chewing, swallowing and pronunciation, the simultaneous stimulation applied to the tongue dorsum and the palate. As stimulation sites were changed from anterior to posterior of the oral cavity, the reversal level in simultaneous stimulation became high. This results agreed with the response characteristic in independent tongue stimulation. When the reversal level in this simultaneous stimulation was compared with the level in the independent stimulation, the former showed a high value, and it became clear that excitement effect reinforced.
    It was suggested that the levator veli palatini muscle was ingeniously controlled by integrative reflexes of tongue and palatal mucosa stimulation.

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  • 口唇製口蓋裂の発生要因と形質転換増殖因子α(TGFA)の関連についての研究

    Grant number:06771906

    1994

    System name:科学研究費助成事業

    Research category:奨励研究(A)

    Awarding organization:日本学術振興会

    小野 和宏

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    Grant amount:\1000000 ( Direct Cost: \1000000 )

    口唇口蓋裂は遺伝因子と環境要因とによって、発症する多因子遺伝病であるといわれていが、その発症に関与する遺伝子については未だ解明されていない。近年、白人を対象とした研究で形質転換増殖因子α(Transforming Growth Factor alpha:TGFA)と口唇口蓋裂の発症の関連が示唆されている(Ardinger et al.1989)。また、マウスでHOX7を破壊すると口蓋裂が発症したと報告している(Satokata et al.1994)。今回このTGFAとHOX7の2つの染色体領域と口唇蓋裂の発症との関連について遺伝学的手法を用いて検索した。(1)TGFAについて[対象]当科をこの1年間に受診した口唇口蓋裂患者83人(唇裂・唇顎裂・唇顎口蓋裂〔CL±P〕70人、口蓋裂単独〔CP〕13人)とコントロールとして健常者117人とした。[実験方法]TGFAのTaq I多型を検討するために、対象者に承諾を得た上で採取した血液よりDNAを抽出し、制限酵素Taq Iで消化後、クローン化したTGFAをプローブとしてサザン法を行った。[結果]3.0kbのバンドのみもつホモ接合体と2.7kbと3.0kbの2本のバンドをもつヘテロ接合体が検出された。ヘテロ接合体の頻度がCL±Pで34%、CPで54%、コントロールで22%で、CPとコントロールとの間に有意差を認めた。また白人では、コントロールでヘテロ接合体の頻度が約10%との報告(Ardinger et al.1989)があり、日本人は白人に比較してその頻度が高かった。(2)HOX7について[対象]口唇口蓋裂患者94人(CL±P77人,CP17人)とコントロール108人とした。[実験方法]HOX7近傍の繰り返し配列を検討するために、その領域を含むようなプライマーを合成し、PCR法を行った。[結果]4つの対立遺伝子が検出され、6つの遺伝子型が認められたが、CL±P、CPそれぞれとコントロールの間で出現頻度に有意差は認められなかった。【まとめ】TGFAのTaq I多型の頻度でCPとコントロールとの間に有意差を認め連鎖不平衡が成立したことより、ヒロの口蓋裂の発生に対してTGFAあるいはTGFA近傍の遺伝子が何らかの関与をしていることが示唆された。また口唇口蓋裂の発生に対してHOX7の関与は認められなかった。

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  • Research for the process of attainning the velopharyngeal function after palatal repair -comparison between three types of the surgery-

    Grant number:05671665

    1993 - 1995

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for General Scientific Research (C)

    Awarding organization:Japan Society for the Promotion of Science

    NAKANO Hisashi, ISONO Shinsaku, ONO Kazuhoro

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    Grant amount:\2200000 ( Direct Cost: \2200000 )

    1) Assessment of preoperative condition of cleft palate : preoperative condition of cleft palate was assessed by intrraoral finding, lateral cephaligram and Echogram of the movement of lateral pharuyugeal wall. We can ralate the velopharyngeal function * iVPF *j with the musclar condition of the soft palate, and the movement of lateral pharyngeal wall with the function of the soft palate. We cannont find the difference of VPF between the isolated cleft palate and the clefi lip and palate.
    2) The process of the attainning of VPF after palate rrepair. A Widmaier method *F Assessment of the VPF after operation with 35 patients was done by intra oral finding, videofluorography, nasopharyngel fiber scope, and echogram. The function was attained at the vowel pronunciation in the 2 years after operation (3 years old). Whereas the function at the consonant pronunciation and blowing was attained about 5 years old. And the function was related to not only the function of the soft palate, but also the lateral wall movement.
    B Furlow's method *F We assessed the VPF of the patients (20 cleft palate, 8 submucous cleft palate, 3 cleft lip and palate) by the same method in A.The function was attained in the 2years after operation (about 3 years old) at almost all the functions. and it was related to the nallowing of velopharyngeal area after operation.
    Secondary plaratal repair by Furlow's method has been done in the patients with velopharyngeal insufficiency after primary repair. In 16 cases after operation, we find the increasing of the mobility of the soft palate and lateral pharyngeal wall in 2-3 montths after operation. And in almost all cases, normal function was attained after 6 months.
    C push back method *F We cannot assessed the function after operation because the case was few and they are complicated with mental retardation or other anomalies related to the speech problem.
    3) Assessment of the speech ; Speech results were assessed about the patients at the 4-6 years old. In the cases after Widmaier palatal repair, normal speech was attained at 4-5years old, however in the cases after Furlow's platal repair normal speech was attained 3-4 years old.

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  • A Study of Secondary Palate Formation in Induced Cleft Palate Rat and Spontaneous Cleft Palate Mouse Embryos.

    Grant number:01440080

    1989 - 1992

    System name:Grants-in-Aid for Scientific Research

    Research category:Grant-in-Aid for General Scientific Research (A)

    Awarding organization:Japan Society for the Promotion of Science

    OHASI Yasushi, NAGATA Masaki, ONO Kazuhiro, NAKANO Hisashi

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    Grant amount:\13800000 ( Direct Cost: \13800000 )

    The mode of development of induced and spontaneous cleft palate is fairly well understood. The differences between this mode of development may have significance in the understanding of the formation of cleft. Hence the palatal development was investigated and compared in experimentally induced cleft palate in rat and spontaneous cleft palate in mouse.
    Results:
    Vitamine A induced cleft palate:The cytokinetic activity was highest and an accumulation of S-phase cell was observed in the nasal aspect of the palatal shelves one day before reorientation. The bone development starts in the central part of maxillary body, and spread to laterally & posteriorly at first and medially & anteriorly later. The vascular plexus of the palatal shelves was denser in the oral side than in the nasal side before reorientation. After reorientation, lateral stretch of vascular plexus and spherical masses along the medial border of the palatal shelves. All these phenomenons were either reduced or absent and certainly delayed about 1-1.5 days than normal group.
    Spontaneous cleft palate:The differentiation of osseous tissue starts lateral to the incisor tooth bud and latero-inferior to the inferior orbital nerve at first and medial to, and surrounding the molar tooth germ later. The area of osteogenesis spread along the medical side of the molar tooth germ. The vascular plexus of the palatal shelves before reorientation was denser in oral than in nasal side. Vascular dilatation was observed in the extreme medical edge of the palatal shelves and was delayed than in the normal group. The spherical masses along the medial border of the palatal shelves were absent and many leakage of resin masses were observed.
    The results show no significant differences between the process of development in spontaneous and experimentally induced cleft palate. Therefore, experimentally induced model might be used for further study.

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  • Randomized Control Trial of Primary Surgery in CLP

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    Grant type:Competitive

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  • 日本における唇顎口蓋裂患者の多施設比較研究

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    Grant type:Competitive

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Teaching Experience

  • 口腔保健福祉学研究ベーシックコース

    2022
    Institution name:新潟大学

  • 歯科衛生士臨床実習III

    2021
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療IIB

    2021
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療IB

    2021
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療IA

    2021
    Institution name:新潟大学

  • 摂食嚥下機能評価支援学特論

    2021
    Institution name:新潟大学

  • 特殊口腔保健管理学II

    2021
    Institution name:新潟大学

  • 社会福祉原論II

    2021
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療IIA

    2021
    Institution name:新潟大学

  • 生命医療科学総論

    2021
    Institution name:新潟大学

  • 医療福祉援助学総論

    2021
    Institution name:新潟大学

  • 高齢者福祉論II

    2021
    Institution name:新潟大学

  • 口腔保健福祉学特定研究

    2021
    Institution name:新潟大学

  • 障害者福祉論II

    2021
    Institution name:新潟大学

  • 児童福祉論II

    2021
    Institution name:新潟大学

  • ネットワーク型先端歯学研究

    2021
    Institution name:新潟大学

  • 人体のしくみ

    2020
    Institution name:新潟大学

  • 口腔と全身との関わり

    2020
    Institution name:新潟大学

  • 歯学スタディ・スキルズⅡ

    2018
    Institution name:新潟大学

  • PBL入門

    2018
    Institution name:新潟大学

  • インターネットテュートリアル

    2017
    -
    2020
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療ⅠA

    2017
    -
    2018
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療ⅡB

    2017
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療ⅠB

    2017
    Institution name:新潟大学

  • チームアプローチによる口唇口蓋裂治療ⅡA

    2017
    Institution name:新潟大学

  • 特殊口腔保健管理学Ⅱ

    2017
    Institution name:新潟大学

  • 教養を考える

    2016
    Institution name:新潟大学

  • 早期臨床実習Ⅱ

    2015
    Institution name:新潟大学

  • 選択実習Ⅰc

    2012
    -
    2017
    Institution name:新潟大学

  • 歯科衛生学Ⅱ

    2011
    Institution name:新潟大学

  • 高齢者福祉論Ⅱ

    2011
    -
    2016
    Institution name:新潟大学

  • 社会福祉原論Ⅱ

    2011
    -
    2016
    Institution name:新潟大学

  • 障害者福祉論Ⅱ

    2011
    -
    2016
    Institution name:新潟大学

  • 児童福祉論Ⅱ

    2011
    -
    2015
    Institution name:新潟大学

  • 歯科予防処置Ⅲ

    2011
    Institution name:新潟大学

  • 老人福祉論Ⅱ

    2011
    Institution name:新潟大学

  • 臨床歯科学Ⅳ

    2010
    Institution name:新潟大学

  • 生命医療科学総論

    2009
    -
    2018
    Institution name:新潟大学

  • 口腔保健医療福祉援助学総論

    2009
    Institution name:新潟大学

  • 特殊口腔保健管理学B

    2009
    Institution name:新潟大学

  • 歯科口腔外科学

    2009
    Institution name:新潟大学

  • 摂食嚥下機能評価支援学B

    2009
    Institution name:新潟大学

  • 歯科診療補助Ⅱ

    2008
    Institution name:新潟大学

  • 早期臨床実習ⅡB

    2008
    Institution name:新潟大学

  • 臨床歯科学Ⅲ

    2008
    Institution name:新潟大学

  • 臨床歯科学Ⅱ

    2008
    Institution name:新潟大学

  • 歯科衛生士臨床実習Ⅱ

    2008
    Institution name:新潟大学

  • 歯科診療補助Ⅰ

    2008
    Institution name:新潟大学

  • 口腔外科学Ⅰ

    2008
    Institution name:新潟大学

  • 歯科衛生士臨床実習Ⅰ

    2008
    -
    2019
    Institution name:新潟大学

  • 歯学研究入門

    2008
    -
    2017
    Institution name:新潟大学

  • 保健指導Ⅲ

    2008
    -
    2011
    Institution name:新潟大学

  • 保健指導Ⅱ

    2008
    -
    2009
    Institution name:新潟大学

  • 歯科予防処置Ⅱ

    2008
    -
    2009
    Institution name:新潟大学

  • 臨床歯学演習

    2007
    Institution name:新潟大学

  • 歯学スタディ・スキルズ

    2007
    Institution name:新潟大学

  • 疾病とその病態

    2007
    Institution name:新潟大学

  • 健康福祉学入門

    2007
    Institution name:新潟大学

  • 口腔の科学

    2007
    Institution name:新潟大学

  • 顎顔面診断・治療学

    2007
    -
    2019
    Institution name:新潟大学

  • 保健指導III

    2007
    Institution name:新潟大学

  • 歯科診療補助I

    2007
    Institution name:新潟大学

  • 歯科予防処置II

    2007
    Institution name:新潟大学

  • 早期臨床実習IIB

    2007
    Institution name:新潟大学

  • 保健指導II

    2007
    Institution name:新潟大学

  • 歯科診療補助II

    2007
    Institution name:新潟大学

  • 歯科衛生士臨床実習I

    2007
    Institution name:新潟大学

  • 歯科衛生士臨床実習II

    2007
    Institution name:新潟大学

  • 臨床歯科学II

    2007
    Institution name:新潟大学

  • 臨床歯科学III

    2007
    Institution name:新潟大学

  • 口腔外科学I

    2007
    Institution name:新潟大学

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