研究者詳細 - 小野　和宏

論文 - 小野　和宏

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An evaluation of problem-based learning course at Niigata University Faculty of Dentisitry 招待査読

Maeda T, Ono K, Ohuchi A, Hayashi T, Saito I, Okiji T, Uoshima K

Dentistry in Japan 43 166 - 171 2007年

本院臨床研修歯科医採用試験におけるミニワークショップの効果

小林哲夫, 魚島勝美, 藤井規孝, 中島貴子, 石崎裕子, 小野和宏, 宮崎秀夫

日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education 22 ( 3 ) 281 - 288 2006年12月

記述言語：日本語出版者・発行元：日本歯科医学教育学会

本研究の目的は、臨床研修歯科医採用試験においてミニワークショップによる評価が有効か否かを検討することである。平成16年12月、新潟大学医歯学総合病院歯科医師臨床研修を希望する者35名を5グループに編成して自由討論を行わせ、5名の評価者がローテーションにより各グループ受験者の態度・コミュニケーション能力を評価した。その後、ミニワークショップによる評価の妥当性を探るためにアンケート調査(受験者・評価者対象)を実施して分析を行うとともに、各試験成績間およびこれらと1年間の臨床研修総括評価との相関について検索した。その結果、1)採用試験の一部としてのミニワークショップは運営上効率的であり、アンケート調査結果からミニワークショップは情意領域の評価に有効であることが示された。2)ミニワークショップ成績は小論文成績と正の相関を示したが、実技成績とは相関がなかった。3)ミニワークショップ成績は臨床研修における情意および認知領域での総括評価と強い正の相関を示した。以上より、ミニワークショップは臨床研修歯科医採用試験での臨床能力評価において有効であり、情意領域のみでなく認知領域の評価をもある程度代替できる可能性が示唆された。今後は評価基準の検討によりさらに信頼性を高める必要がある。(著者抄録)

Hotz 床併用二段階口蓋形成法の長期予後 : 片側症例の成長終了時側面頭部エックス線規格写真による評価

高木律男, 福田純一, 小野和宏, 飯田明彦, 朝日藤寿一, 寺田員人, 齋藤功

日本口蓋裂学会雑誌 31 ( 3 ) 245 - 252 2006年10月

Localization of CD44 and hyaluronan in the synovial membrane of the rat temporomandibular joint 査読

Akiko Suzuki, Kayoko Nozawa-Inoue, Norio Amizuka, Kazuhiro Ono, Takeyasu Maeba

Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology 288 ( 6 ) 646 - 652 2006年6月

記述言語：英語掲載種別：研究論文（学術雑誌）

Previous studies have pointed out a lack of adhesion structures in the synovial lining layer of the rat temporomandibular joint (TMJ) despite showing an epithelial arrangement. CD44, a major cell adhesion molecule, plays crucial roles as an anchor between cells and extracellular matrices by binding hyaluronan (HA) for the development of organs or the metastasis of tumors. The present study examined the localization of CD44 in the synovial membrane of the rat TMJ by immunocytochemistry for OX50, ED1, and Hsp25, which are markers for the rat CD44, macrophage-like type A, and fibroblast-like type B synoviocytes, respectively. Histochemistry for HA-binding protein (HABP) was also employed for the detection of HA. OX50 immunoreactions were found along the cell surface and, in particular, accumulated along the surface of the articular cavity. Observations by a double immunostaining and immunoelectron microscopy revealed that all the OX50-immunopositive cells were categorized as fibroblastic type B cells, which had many caveolae and a few vesicles reactive to intense OX50. However, the macrophage-like type A cells did not have any OX50 immunoreaction in the synovial lining layer. A strong HABP reaction was discernable in the extracellular matrix surrounding both OX50-positive and -negative cells in the synovial lining layers, exhibiting a meshwork distribution, but weak in its sublining layer. This localization pattern of CD44 and HABP might be involved in the formation of the epithelial arrangement of the synovial lining layer. Furthermore, OX50 immunonegativity in the type A cells suggests their low phagocytotic activity in the rat TMJ under normal conditions. © 2006 Wiley-Liss, Inc.

DOI： 10.1002/ar.a.20331

Localization of CD44 and hyaluronan in the synovial membrane of the rat temporomandibular joint 査読

A Suzuki, K Nozawa-Inoue, N Amizuka, K Ono, T Maeda

ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY 288A ( 6 ) 646 - 652 2006年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：WILEY-LISS

Previous studies have pointed out a lack of adhesion structures in the synovial lining layer of the rat temporomandibular joint (TMJ) despite showing an epithelial arrangement. CD44, a major cell adhesion molecule, plays crucial roles as an anchor between cells and extracellular matrices by binding hyaluronan (HA) for the development of organs or the metastasis of tumors. The present study examined the localization of CD44 in the synovial membrane of the rat TMJ by immunocytochemistry for OX50, ED1, and Hsp25, which are markers for the rat CD44, macrophage-like type A, and fibroblast-like type B synoviocytes, respectively. Histochemistry for HA-binding protein (HABP) was also employed for the detection of HA. OX50 immunoreactions were found along the cell surface and, in particular, accumulated along the surface of the articular cavity. Observations by a double immunostaining and immunoelectron microscopy revealed that all the OX50-immunopositive cells were categorized as fibroblastic type B cells, which had many caveolae and a few vesicles reactive to intense OX50. However, the macrophage-like type A cells did not have any OX50 immunoreaction in the synovial lining layer. A strong HABP reaction was discernable in the extracellular matrix surrounding both OX50-positive and -negative cells in the synovial lining layers, exhibiting a meshwork distribution, but weak in its sublining layer. This localization pattern of CD44 and HABP might be involved in the formation of the epithelial arrangement of the synovial lining layer. Furthermore, OX50 immunonegativity in the type A cells suggests their low phagocytotic activity in the rat TMJ under normal conditions.

DOI： 10.1002/ar.a.20331

歯科医学教育へのPBLテュートリアルの導入 : 新潟大学歯学部の試み

小野和宏, 大内章嗣, 魚島勝美, 林孝文, 西山秀昌, 安島久雄, 小林正治, 瀬尾憲司, 齋藤功, 程〓, 山田好秋, 前田健康

日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education 22 ( 1 ) 58 - 71 2006年4月

記述言語：日本語出版者・発行元：日本歯科医学教育学会

新潟大学歯学部歯学科では平成16年度より5年次の授業にPBLテュートリアルを導入した.1年次に教えられる学習から自ら学ぶ学習態度への転換,またその学習法としてのスタディ・スキルズを習得させ,3年次に医学教育開発研究センター主催の「楽位置楽The Tutorial」への参加によりPBLの原理を理解させた後に,部分的折衷型カリキュラムで実施している.このPBLテュートリアルは,4年次までに学習した基礎科学と臨床歯学の知識を統合させ,疾患概念を構築し,治療の原則を理解すること,また臨床実習前に,医療人としての在り方を深く考えさせることを教育の目標とし,基礎および臨床の8分野が参加している.このカリキュラムで学習した平成16,17年度5年生,計107名のアンケート結果では,約9割の学生がPBLテュートリアルをこれからの歯科医師としてのキャリアに重要と捉えていた.また,約8割の学生がPBLテュートリアルでの学習を有意義と感じており,科目別の知識の統合と理解の深化,学習意欲の高まり,問題発見・解決能力や対人関係能力の向上を自覚していた.PBLテュートリアルの実施にあたっては,学習内容と量を十分に検討し,それに見合う自習時間を確保すること,また,学生主体の学習を補う支援授業の開催や,学習を促進させる教員の養成が重要と考えられた(著者抄録)

Blepharo-cheilo-dontic (BCD) syndrome: Case report 査読

A Iida, S Narai, R Takagi, K Ono, N Ikeda

CLEFT PALATE-CRANIOFACIAL JOURNAL 43 ( 2 ) 237 - 243 2006年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ALLIANCE COMMUNICATIONS GROUP DIVISION ALLEN PRESS

Objective: To report a case of blepharo-cheilo-dontic (BCD) syndrome, to compare with the previous cases, and to discuss the possible treatment.
Patient: The patient was a 14-day-old boy born uneventfully on August 7, 2002. His scalp hair was sparse and curly. A tumor on the top of his head, which was thought to be a dermoid cyst, and a nevus on the back of his left hand were observed. All typical symptoms of blepharo-cheilo-dontic syndrome, such as euryblepharon with ectropion of the lower eyelids, distichiasis, bilateral cleft lip and palate, severe oligodontia, and conical teeth, were observed. Because there was no fatal complication, and growth and development were about normal, it was recommended that a long and active treatment plan be considered for this patient.

DOI： 10.1597/04-200.1

小児開口障害の2例

安島久雄, 高木律男, 今井信行, 小野和宏, 飯田明彦, 嵐山貴徳

小児口腔外科 = Pediatric oral and maxillofacial surgery 15 ( 2 ) 118 - 124 2005年12月

記述言語：日本語出版者・発行元：JAPANESE SOCIETY OF PEDIATRIC ORAL AND MAXILLOFACIAL SURGERY

It is necessary for dentists to control the mandibular hypomobility in children even if it happens relatively rarely. In this case report, we present two different causes for limitation of mouth opening.<BR>They have morphological abnormalities in their unilateral masticatory muscles on the CTs, but there is no abnormal finding around their temporomandibular joints. Case 1 is a 3 year-old boy who had a history of cranial operations several times due to multi-located brain vascular malformations. On his CTs, atrophic changes were detected in some masticatory muscles that were controlled under facial and trigeminal nerves. Case 2 is a one-year old boy who has a congenital wryneck. His temporal muscle reveals hypertrophy on his CTs. Dystonia of masticatory muscle was suspected from these findings as well as his sternocleid muscle of his wryneck. At the present time, it is very difficult to detect in detail such as electro-myographies about their pathology because of his younger age. Therefore, we will observe his oral conditions and follow up for a long time.

DOI： 10.11265/poms1991.15.118

進行性顔面片側萎縮症の歯科矯正外科治療(Progressive Hemifacial Atrophy Treated by Orthodontic Surgery)

Kodama Yasumitsu, Miyazawa Marta, Fukuda Jun-ichi, Iida Akihiko, Ono Kazuhiro, Takagi Ritsuo

Oral Science International 2 ( 2 ) 131 - 135 2005年11月

記述言語：英語出版者・発行元：エルゼビア・ジャパン(株)

進行性顔面片側萎縮症(PHA)は顔面の片側に生じる自己限定的な皮下組織萎縮であり,硬組織性は稀である.散発性の緩徐進行性疾患であり,病因については不明である.基本的に,PHA(通常は軟部組織)による顔面非対称治療は容積増強術によって行われる.硬組織PHAの稀症例について述べた.症例は15歳男児であった.左大臼歯,上顎および下顎に萎縮性変化が生じ,中程度の軟部組織萎縮が伴っていた.口部は右側上方に傾斜し,正常咬合にも関らず咬合平面は重度に傾斜していた.萎縮性変化および進行の停止を認めた後に,歯科矯正手術を行った.咬合平面および顔面非対称を矯正するために,Le Fort Iおよび両側下顎枝垂直骨切術を行った.3年後の追加調査では,咬合平衡は良好で,顔面対称性も改善し,萎縮再発は認められなかった.このように,中程度の軟部組織萎縮を伴う硬組織萎縮の第一手段として,歯科矯正外科は有効であった

DOI： 10.11277/osi.2.131

若年者の顎矯正手術後に生じた深部静脈血栓症の1例

津端久美子, 福田純一, 藤田一, 安島久雄, 小野和宏, 高木律男

日本口腔外科学会雑誌 51 ( 10 ) 520 - 523 2005年10月

記述言語：日本語出版者・発行元：社団法人日本口腔外科学会

Deep venous thrombosis (DVT) is caused by obstruction of blood flow of the deep vein of the leg and accelerated blood coagulating activity. DVT may occur after an operation. However, there are few reports of DVT associated with surgery of the oral and maxillofacial region, especially in young adults.<BR>We report a case of DVT occurring after orthognathic surgery in a 19-year-old woman at our hospital. She had facial asymmetry and underwent Le Fort I osteotomy of the maxilla combined with sagittal splitting ramus osteotomy and intraoral vertical ramus osteotomy of the mandible under general anesthesia. Although she was able to walk the next day, symptoms of DVT appeared 3 days after the operation. On the 18th day after the first operation, surgery to remove the thrombus was performed by cardiovascular surgeons. She was discharged on the 34th day after the first operation.<BR>Orthognathic surgery is not free of the risk of DVT, which can cause fatal acute pulmonary thromboembolism. Therefore, it is necessary to prevent DVT after orthognathic surgery, even in young adults.

DOI： 10.5794/jjoms.51.520

Development of the articular cavity in the rat temporomandibular joint with special reference to the behavior of endothelial cells and macrophages 査読

Akiko Suzuki, Kayoko Nozawa-Inoue, Nobuyuki Ikeda, Norio Amizuka, Kazuhiro Ono, Ritsuo Takagi, Takeyasu Maeda

Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology 286 ( 2 ) 908 - 916 2005年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

Previous developmental studies on the temporomandibular joint (TMJ) have proposed several hypotheses on the formation of its articular cavity. However, detailed information is meager. The present study examined the formation process of the articular cavity in the rat TMJ by immunocytochemistry for CD31, RECA-1, and ED1, which are useful cellular markers for endothelial cells and monocyte/macrophage lineages, respectively. The upper articular cavity formation had begun by embryonic day 21 (E21) and was completed at postnatal day 1 (P1) in advance of the lower cavitation
the latter took place from P1 to P3. The occurrence and distribution pattern of the CD31-, RECA-1-, and ED1-positive cells differed between the upper and lower articular cavity-forming areas: the ED1-positive cells exclusively occurred in the area of the prospective upper articular cavity prior to its formation, while no ED1-positive cell appeared in the lower cavity-forming area. In contrast, the CD31- and RECA-1-positive endothelial cells were restricted to the lower cavity-forming area (never the prospective upper cavity) at E19 and diminished thereafter. Throughout the cavity formation, we failed to find any apoptotic cells in the cavity formation area, indicating no involvement of apoptosis in the cavity formation in TMJ. The present findings on the behaviors of endothelial cells and ED1-positive cells show a possibility of different mechanism in the cavity formation between the upper and lower articular cavities in the rat TMJ. The appearance of ED1-reactive cells and temporal vascularization may play crucial roles in the upper and lower articular cavity formation, respectively. © 2005 Wiley-Liss, Inc.

DOI： 10.1002/ar.a.20228

Development of the articular cavity in the rat temporomandibular joint with special reference to the behavior of endothelial cells and macrophages 査読

A Suzuki, K Nozawa-Inoue, N Ikeda, N Amizuka, K Ono, R Takagi, T Maeda

ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY 286A ( 2 ) 908 - 916 2005年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：WILEY-LISS

Previous developmental studies on the temporomandibular joint (TMJ) have proposed several hypotheses on the formation of its articular cavity. However, detailed information is meager. The present study examined the formation process of the articular cavity in the rat TMJ by immunocytochemistry for CD31, RECA-1, and ED1, which are useful cellular markers for endothelial cells and monocyte/macrophage lineages, respectively. The upper articular cavity formation had begun by embryonic day 21 (E21) and was completed at postnatal day 1 (P1) in advance of the lower cavitation; the latter took place from P1 to P3. The occurrence and distribution pattern of the CD31-, RECA-1-, and ED1-positive cells differed between the upper and lower articular cavity-forming areas: the ED1-positive cells exclusively occurred in the area of the prospective upper articular cavity prior to its formation, while no ED1-positive cell appeared in the lower cavity-forming area. In contrast, the CD31- and RECA-1-positive endothelial cells were restricted to the lower cavity-forming area (never the prospective upper cavity) at E19 and diminished thereafter. Throughout the cavity formation, we failed to find any apoptotic cells in the cavity formation area, indicating no involvement of apoptosis in the cavity formation in TMJ. The present findings on the behaviors of endothelial cells and ED1-positive cells show a possibility of different mechanism in the cavity formation between the upper and lower articular cavities in the rat TMJ. The appearance of ED1-reactive cells and temporal vascularization may play crucial roles in the upper and lower articular cavity formation, respectively. (C) 2005 Wiley-Liss, Inc.

DOI： 10.1002/ar.a.20228

二段階法における Furlow 法による軟口蓋形成後の硬口蓋裂の推移と硬口蓋閉鎖術について

飯田明彦, 高木律男, 小野和宏, 永田昌毅, 寺尾恵美子, 児玉泰光, 小山貴寛, 小林孝憲, 奈良井省太

日本口蓋裂学会雑誌 30 ( 2 ) 70 - 70 2005年4月

垂直的歯槽骨延長法を用いて顎堤形成を行った1例

小野和宏, 小林正治, 安島久雄, 高木律男, 毛利環, 橋本明彦, 田中礼

新潟歯学会雑誌 34 ( 2 ) 219 - 224 2005年1月

記述言語：日本語出版者・発行元：新潟歯学会

17歳女.9歳時に中心性血管腫の診断にて輸入血管塞栓術後に下顎骨部分切除術を施行された.咀嚼障害と審美障害を主訴に顎堤形成目的で来診した.両側中切歯・側切歯・犬歯の6歯を含め下顎骨が切除されていたため,歯槽骨欠損に対してプレート型延長装置を用いて垂直的歯槽骨延長法を施行した.その結果,延長装置は小型で患者にとって違和感がなく,感染など合併症も認められず,形成された顎堤は高さ・幅共に良好でインプラントにより機能的にも審美的にも満足いく咬合が再建された.以上より垂直的歯槽骨延長法は従来の骨移植と比較して術式が簡単かつ安全で,骨の採取不用・術後の骨吸収が少ない・骨延長に制限がない・骨周囲の骨膜や軟組織も延長するなど多くの利点を有し,歯槽骨欠損に対する有用な治療方法であるものと考えられた

歯学教育プログラムへのPBL教育の導入 : 南カリフォルニア大学歯学部における実態調査

安島久雄, 小野和宏, 前田健康, 永田昌毅, 高木律男, 山田好秋, 興地隆史, 魚島勝美, 葭原明弘, 花田晃治

日本歯科医学教育学会雑誌 = Journal of Japanese Association for Dental Education 20 ( 1 ) 166 - 173 2004年12月

記述言語：日本語出版者・発行元：日本歯科医学教育学会

2001年12月に新潟大学の教員6名が南カリフォルニア大学歯学部を訪れ,米国人学生とともにPBL(問題解決型学習)教育を1週間体験した.また,PBLの概念,教科課程編成法,教材の作成法,評価方法などについて資料収集を行った.その結果,PLBでは問題への解答よりも学習者中心の問題解決過程を通じた理解の育成が重視されること,教員の役割は知識の伝授ではなくグループの作業プロセスを支援して学習目標への到達を促すものであることなどが確認された

<臨床>垂直的歯槽骨延長法を用いて顎堤形成を行った1例

小野和宏, 小林正治, 安島久雄

新潟歯学会雑誌 34 ( 2 ) 55 - 60 2004年12月

記述言語：日本語出版者・発行元：新潟大学

Vertical alveolar distraction was first described by Chin and Toth in 1996. This method is an alternative procedure for augmentation of the alveolar ridge. A segmental osteotomy mobilizes the bone for transport. By using controlled, gradual distraction, it is possible to enlarge the segment of the bone and reconstruct the alveolar ridge. This paper presented our first experience with alveolar ridge distraction in a patient with a bone defect after segmental resection in tumor surgery. An internal distraction device (LEAD system(R), LEIBINGER) was used. This device achieved patient acceptability and comfort. Distraction osteogenesis was successfully done to correct the alveolar process deficiency without any complications. Correction of the site of deficiency made it possible to rehabilitate the dentition using osseointegrated implants. Vertical alveolar distraction seems to have many advantages compared with autogenous onlay bone grafting. The advantages are as follows ; easy and safe technique, no donor site morbidity, less bone resorption, no limitation of distraction, expanding the overlying soft tissue while distraction osteogenesis.垂直的歯槽骨延長法は、1996年にChin and Tothにより初めて報告された顎堤形成法である｡骨切りした歯槽骨片を延長装置により徐々に上方に移動させ、骨断端間に新たな骨を再生させることにより、顎堤の高さを回復する。今回、腫瘍切除後の歯槽骨欠損に対して、プレート型延長装置(LEIBINGER社製LEADシステム(R))を用いて、垂直的歯槽骨延長法を施行した1例を経験した｡延長装置は小型で、患者にとって違和感はなく、また、感染などの合併症は認められなかった｡形成された顎堤は高さ、幅ともに良好で、インプラントにより機能的にも審美的にも満足いく咬合を再建可能であった｡垂直的歯槽骨延長法は、これまでおもに行われてきた骨移植と比較して、術式が簡単で安全、骨の採取が不要、術後の骨吸収が少ない、骨延長量に制限がない、骨周囲の骨膜や軟組織も延長するなどさまざまな利点を有し、歯槽骨欠損に対する有用な治療方法と考えられた｡

Linkage analysis between BCL3 and nearby genes on 19q13.2 and non-syndromic cleft lip with or without cleft palate in multigenerational Japanese families 査読

H Fujita, M Nagata, K Ono, H Okubo, R Takagi

ORAL DISEASES 10 ( 6 ) 353 - 359 2004年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BLACKWELL MUNKSGAARD

OBJECTIVE: To investigate the linkage between candidate genes on chromosome 19 and cleft lip with or without cleft palate in Japanese using a parametric method.
MATERIALS AND METHODS: After informed consent was obtained, blood samples were drawn from 90 individuals in 14 families, 30 of whom were affected, and genomic DNAs were extracted. PCR-amplified products using four microsatellite markers, D19S178, BCL3, APOC2[007/008] and APOC2[AC1/AC2] located in 19q13.2, were separated by 8% polyacrylamide gel electrophoresis. Linkage analysis was carried out using the MLINK and LINKMAP programs, and logarithm of odds (LOD) scores were calculated for each family.
RESULTS: Before undertaking linkage analysis, we analyzed 74 healthy Japanese subjects and found racial differences in that the observed number of alleles and their heterozygosity were lower in Japanese than in Caucasians, and that both populations tended to show a different allele distribution. In 14 families, two-point maximum LOD score (Z(max)) for BCL3 was 0.341 and multi-point Z(max) was less than -2 excluding linkage. But in 9 families with left and bilateral CL/P, two-point Z(max) for APOC2[AC1/AC2] was 1.701 and multi-point Z(max) at APOC2 locus was 1.909.
CONCLUSION: The LOD score was relatively high but provided no evidence of linkage for CL/P to BCL3 and nearby genes in Japanese subjects.

晩期成長による再発が疑われた下顎非対称の1例

児玉泰光, 福田純一, 藤田一, 安島久雄, 小野和宏, 高木律男

日本口腔外科学会雑誌 50 ( 7 ) 422 - 425 2004年7月

記述言語：日本語出版者・発行元：(公社)日本口腔外科学会

症例は14歳女子で,12歳時に顎矯正手術適応と診断され,成長のスパートまで経過観察となった.14歳時,術前矯正治療開始時期と判断され来院,画像所見では上下顎とも正中に対し左側偏位を認め,偏位量はオトガイ部12mm,下顎前歯正中9mm,上顎前歯正中4.5mmで,骨格性下顎前突を呈していた.下顎非対称による下顎前突症と臨床診断し,術前矯正治療後に下顎枝垂直骨切り術を施行,オトガイの左側偏位と下顎の前突,咬合関係は改善した.術後5年8ヵ月を経過し,成長に伴い下顎の左側偏位と左側臼歯部の交叉咬合が著明となり再診した.画像所見で前回同様に上下顎とも正中に対し左側偏位を認め,偏位量はオトガイ部14mm,下顎前歯正中9mm,上顎前歯正中4.5mmで,晩期成長による下顎非対称再発の臨床診断にて,術前矯正治療後に下顎枝矢状分割術+Miniplateによる骨接合術を施行した.その結果,オトガイ部は顔面正中に位置し上下顎前歯正中も一致し,術後2年の現在も咬合関係は安定している

DOI： 10.5794/jjoms.50.422

その他リンク： http://search.jamas.or.jp/link/ui/2005001947

2人乗り自転車前転事故による小児顎関節突起完全骨折の2例

小林孝憲, 高木律男, 小野和宏, 飯田明彦, 碓井由紀子, 安島久雄

日本口腔外科学会雑誌 50 ( 4 ) 231 - 234 2004年4月

記述言語：日本語出版者・発行元：(公社)日本口腔外科学会

症例1は5歳で,閉口不能を主訴とした.石につまずき前のめりに転倒し,オトガイ部を路面に強打した.正貌にてオトガイ正中に裂創を認め,左側頬部に顎角部にびまん性に腫脹していた.左側顎関節突起は完全骨折し,下内方へ転位していた.経口摂食困難であったため経鼻栄養チューブを挿入し,囲繞結紮術を施行した.術後8ヵ時での顎運動障害,顎関節部の疼痛や雑音は認めていない.症例2は2歳男で,オトガイ部を路面に強打した.下顎頭が両側ともに内方へ大きく脱臼し,右側関節突起では内側皮質骨の連続が認められたが左側は完全骨折であった.囲繞結紮術を施行し,術後1年で右側はほぼ正常下顎頭と同様の形態を示し,左側では内方と外方へ突起を伸ばした双頭下顎頭の形態を呈した

DOI： 10.5794/jjoms.50.231

その他リンク： http://search.jamas.or.jp/link/ui/2004212173

日本人口唇・口蓋裂患者における分子遺伝学的研究

藤田一, 永田昌毅, 小野和宏, 飯田明彦, 碓井由紀子, 児玉泰光, 大久保博基, 奈良井省太, 小林孝憲, 高木律男

新潟歯学会雑誌 33 ( 2 ) 273 - 275 2004年1月

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