Faculty Profiles - SONE, Hirohito

Papers - SONE, Hirohito

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Risk of Cardiovascular Diseases Is Increased Even with Mild Diabetic Retinopathy The Japan Diabetes Complications Study Reviewed

Ryo Kawasaki, Shiro Tanaka, Sachiko Tanaka, Sachi Abe, Hirohito Sone, Koutaro Yokote, Shun Ishibashi, Shigehiro Katayama, Yasuo Ohashi, Yasuo Akanuma, Nobuhiro Yamada, Hidetoshi Yamashita

OPHTHALMOLOGY 120 ( 3 ) 574 - 582 2013.3

The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic-non-obese type 2 diabetic rats: A differential role of unfolded protein response (UPR) signaling proteins Reviewed

Arun Prasath Lakshmanan, Meilei Harima, Kenji Suzuki, Vivian Soetikno, Masaki Nagata, Takashi Nakamura, Toshihiro Takahashi, Hirohito Sone, Hiroshi Kawachi, Kenichi Watanabe

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 45 ( 2 ) 438 - 447 2013.2

Association Between Physical Activity and Risk of All-Cause Mortality and Cardiovascular Disease in Patients With Diabetes A meta-analysis Reviewed

Satoru Kodama, Shiro Tanaka, Yoriko Heianza, Kazuya Fujihara, Chika Horikawa, Hitoshi Shimano, Kazumi Saito, Nobuhiro Yamada, Yasuo Ohashi, Hirohito Sone

DIABETES CARE 36 ( 2 ) 471 - 479 2013.2

Metabolic predictors of ischemic heart disease and cerebrovascular attack in elderly diabetic individuals: Difference in risk by age Reviewed

Toshio Hayashi, Atsushi Araki, Seinosuke Kawashima, Hirohito Sone, Hiroshi Watanabe, Takashi Ohrui, Koutaro Yokote, Minoru Takemoto, Kiyoshi Kubota, Mitsuhiko Noda, Hiroshi Noto, Koichiro Ina, Hideki Nomura

Cardiovascular Diabetology 12 ( 1 ) 10 2013.1

Diabetes and Risk of Hearing Impairment in Adults: A Meta-Analysis Reviewed

Chika Horikawa, Satoru Kodama, Shiro Tanaka, Kazuya Fujihara, Reiko Hirasawa, Yoko Yachi, Hitoshi Shimano, Nobuhiro Yamada, Kazumi Saito, Hirohito Sone

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 98 ( 1 ) 51 - 58 2013.1

Nutrition education in Japanese medical schools: A follow-up survey Reviewed

Hideo Orimo, Takahiro Ueno, Hiroshi Yoshida, Hirohito Sone, Akira Tanaka, Hiroshige Itakura

Asia Pacific Journal of Clinical Nutrition 22 ( 1 ) 144 - 149 2013.1

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin Reviewed

Ayano Naka, Kaoruko Tada Iida, Yoshimi Nakagawa, Hitoshi Iwasaki, Yoshinori Takeuchi, Aoi Satoh, Takashi Matsuzaka, Kiyo-aki Ishii, Kazuto Kobayashi, Shigeru Yatoh, Masako Shimada, Naoya Yahagi, Hiroaki Suzuki, Hirohito Sone, Nobuhiro Yamada, Hitoshi Shimano

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 430 ( 2 ) 664 - 669 2013.1

Low BMI at age 20years predicts gestational diabetes independent of BMI in early pregnancy in Japan: Tanaka Women's Clinic Study Reviewed

Y. Yachi, Y. Tanaka, I. Nishibata, A. Sugawara, S. Kodama, K. Saito, H. Sone

Diabetic Medicine 30 ( 1 ) 70 - 73 2013.1

The Relationship between Diabetic Neuropathy and Sleep Apnea Syndrome: A Meta-Analysis. Reviewed International journal

Kazuya Fujihara, Satoru Kodama, Chika Horikawa, Sakiko Yoshizawa, Ayumi Sugawara, Reiko Hirasawa, Hitoshi Shimano, Yoko Yachi, Akiko Suzuki, Osamu Hanyu, Hirohito Sone

Sleep disorders 2013 150371 - 150371 2013

Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)

Aims. High prevalence of sleep apnea syndrome (SAS) has been reported in patients with diabetes. However, whether diabetic neuropathy (DN) contributes to this high prevalence is controversial. Our aim of this study is to compare the prevalence of SAS between patients with and without DN. Methods. Systematic literature searches were conducted for cross-sectional studies that reported the number of patients with DN and SAS using MEDLINE (from 1966 to Nov 5, 2012) and EMBASE (from 1974 to Nov 5, 2012). Odds ratios (ORs) of SAS related to DN were pooled with the Mantel-Haenszel method. Results. Data were obtained from 5 eligible studies (including 6 data sets, 880 participants, and 429 cases). Overall, the pooled OR of SAS in patients with DN compared with that in non-DN patients was significant (OR (95% CI), -1.95 (1.03-3.70)). The pooled OR of SAS was 1.90 (0.97-3.71) in patients with type 2 diabetes. Excluding data on patients with type 1 diabetes, a higher OR was observed in younger patients (mean age <60 years) than in those ≥60 years among whom the OR remained significant (3.82; 95% CI, 2.24-6.51 and 1.17; 95% CI, 0.81-1.68). Conclusions. Current meta-analysis suggested the association of some elements of neuropathy with SAS in type 2 diabetes. Further investigations are needed to clarify whether the association is also true for patients with type 1 diabetes.

DOI： 10.1155/2013/150371

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Carotid artery plaque and LDL-to-HDL cholesterol ratio predict atherosclerotic status in coronary arteries in asymptomatic patients with type 2 diabetes mellitus Reviewed

Kazuya Fujihara, Hiroaki Suzuki, Akira Sato, Satoru Kodama, Yoriko Heianza, Kazumi Saito, Hitoshi Iwasaki, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Nobuhiro Yamada, Hirohito Sone, Hitoshi Shimano

Journal of Atherosclerosis and Thrombosis 20 ( 5 ) 452 - 464 2013

Various Components of Blood Pressure as Stroke Risk in Japanese Patients With Type 2 Diabetes: Analysis from the Japan Diabetes Complications Study (JDCS)

Hirohito Sone

Diabetes 2013

Combined Risk of Alcohol Intake and Smoking for Development of Type 2 Diabetes in the General Population in Japan: The Ibaraki Prefectural Health Study

Hirohito Sone

Diabetes 2013

Effects of Recommendation Notices for Clinic Visits by Nationwide Health Screening System in Japan

Hirohito Sone

Diabetes 2013

Elovl6 Promotes Nonalcoholic Steatohepatitis Reviewed

Takashi Matsuzaka, Ayaka Atsumi, Rie Matsumori, Tang Nie, Haruna Shinozaki, Noriko Suzuki-Kemuriyama, Motoko Kuba, Yoshimi Nakagawa, Kiyoaki Ishii, Masako Shimada, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Kazuhiro Takekoshi, Hirohito Sone, Naoya Yahagi, Hiroaki Suzuki, Soichiro Murata, Makoto Nakamuta, Nobuhiro Yamada, Hitoshi Shimano

HEPATOLOGY 56 ( 6 ) 2199 - 2208 2012.12

Development of a new scoring system for predicting the 5 year incidence of type 2 diabetes in Japan: the Toranomon Hospital Health Management Center Study 6 (TOPICS 6) Reviewed

Y. Heianza, Y. Arase, S. D. Hsieh, K. Saito, H. Tsuji, S. Kodama, S. Tanaka, Y. Ohashi, H. Shimano, N. Yamada, S. Hara, H. Sone

Diabetologia 55 ( 12 ) 3213 - 3223 2012.12

Enhancement of antigen presenting ability in the leukemic plasmacytoid dendritic cell line (PMDC05) by lentiviral vector-mediated transduction of CD80 gene Reviewed

Akie Yamahira, Miwako Narita, Kayoko Ishii, R. M. Chamila Jayathilake, Minami Iwabuchi, Naoya Satoh, Takayoshi Uchiyama, Tomoyo Taniguchi, Shigeo Hashimoto, Noriyuki Kasahara, Emmanuelle Faure, Brooke Bogan, Jun Takizawa, Hirohito Sone, Masuhiro Takahashi

LEUKEMIA RESEARCH 36 ( 12 ) 1541 - 1546 2012.12

Cholesterol sulfate induces expression of the skin barrier protein filaggrin in normal human epidermal keratinocytes through induction of ROR alpha Reviewed

Osamu Hanyu, Hanako Nakae, Takashi Miida, Yuko Higashi, Hirotoshi Fuda, Motohiro Endo, Atsushi Kohjitani, Hirohito Sone, Charles A. Strott

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 428 ( 1 ) 99 - 104 2012.11

Self-reported rate of eating is significantly associated with body mass index in Japanese patients with type 2 diabetes. Japan Diabetes Clinical Data Management Study Group (JDDM26) Reviewed

Aki Saito, Koichi Kawai, Morifumi Yanagisawa, Hiroki Yokoyama, Nobuichi Kuribayashi, Hidekatsu Sugimoto, Mariko Oishi, Takako Wada, Koichi Iwasaki, Azuma Kanatsuka, Noriharu Yagi, Fuminobu Okuguchi, Kazuhiro Miyazawa, Keiko Arai, Kazumi Saito, Hirohito Sone

APPETITE 59 ( 2 ) 252 - 255 2012.10

Development of Coronary Heart Disease and Cerebral Stroke in Japanese Elderly Patients with Nonalcoholic Fatty Liver Diseases

OGAWA Kyoko, OHMONTO SEKINE Yuki, HARA Shigeko, OKUDA Chikao, AMAKAWA Kazuhisa, ARIMOTO Satao, KATO Hisahito, HSIEH Shiun Dong, TANABE Maho, OGATA Chie, ISHIHARA Makiko, TSUJI Hiroshi, SAITO Kazumi, KODAMA Satoru, SONE Hirohito, ARASE Yasuji

Official Journal of the Japanese Society of Human Dry Dock 27 ( 3 ) 561 - 567 2012.9

Language：English Publisher：Japan Society of Ningen Dock

Objective: Metabolic syndrome enhances coronary heart disease and cerebral stroke. However, few longitudinal studies have been conducted on the incidence of coronary heart disease and cerebral stroke in Japanese patients with non-alcoholic fatty liver disease (NAFLD) and the risk factors for its development. Methods: A total of 1,798 NAFLD patients with an age of ≥60 years were enrolled. The primary event was the first onset of coronary heart disease or cerebral stroke. Independent factors associated with the incidence rate of such events were analyzed by the Kaplan-Meyer method and the Cox proportional hazard model. The mean observation period was 7.5 years. Results: The number of cases of coronary heart disease or cerebral stroke that developed was 137. The 10th year cumulative development rate was 11.7% in the NAFLD patients. Cox proportional hazards analysis revealed the following: 1) Coronary heart disease occurred with statistical significance when patients had poor control of blood pressure, smoking, low high density lipoprotein level, and high glucose level. 2) Ischemic stroke occurred with statistical significance when patients had poor control of blood pressure, an age of ≥70 years, and high glucose level. 3) Hemorrhagic stroke occurred with statistical significance when patients had poor control of blood pressure, age ≥70 years, low albumin level of <3.9 g/dL and high aspartate aminotransferase to platelet ratio index. Conclusion: Our study indicates that the risk factors for the development of vascular disease are different for coronary heart disease, ischemic stroke and hemorrhagic stroke in Japanese elderly patients with NAFLD.

DOI： 10.11320/ningendock.27.561

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Other Link： https://jlc.jst.go.jp/DN/JALC/10009979603?from=CiNii

Screening for pre-diabetes to predict future diabetes using various cut-off points for HbA1c and impaired fasting glucose: the Toranomon Hospital Health Management Center Study 4 (TOPICS 4)

Y. Heianza, Y. Arase, K. Fujihara, H. Tsuji, K. Saito, S. D. Hsieh, S. Kodama, H. Shimano, N. Yamada, S. Hara, H. Sone

DIABETIC MEDICINE 29 ( 9 ) E279 - E285 2012.9

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Papers - SONE, Hirohito