Faculty Profiles - SONE, Hirohito

Papers - SONE, Hirohito

Division display 601 - 618 of about 618 ／ All the affair displays >>

Effects of life style modification on patients with type 2 diabetes: The Japan Diabetes Complications Study (JDCStudy)

Hirohito Sone

Diabetes 2000

Increased mutant frequency and altered mutation spectrum of the lacI transgene in Wilson disease rats with hepatitis

Hirohito Sone

Cancer Research 2000

Vascular endothelial GLUT1 overexpression activates multiple signal transduction pathways

Hirohito Sone

Diabetes 1999

Glucose-mediated regulation of glucose transport and GLUT1 expression in different retinal cells in culture

Hirohito Sone

Diabetes 1999

Vascular endothelial growth factor levels in the aqueous and serum in diabetic retinopathy with or without neovascular glaucoma Reviewed

Tadahiko Kozawa, Hirohito Sone, Yukichi Okuda, Yasushi Kawakami, Yasuo Sekine, Masayuki Imai, Sachiko Hommura, Makoto Inatomi, Shigeo Yaguchi, Katsuhiko Matsuo, Toshiaki Segawa, Hideo Suzuki, Kamejiro Yamashita

Journal of Japanese Ophthalmological Society 102 ( 11 ) 731 - 738 1998.11

Language：Japanese Publishing type：Research paper (scientific journal)

We determined the levels of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in the aqueous and serum in non-insulin dependent diabetic patients with proliferative retinopathy (n=12) and neovascular glaucoma (n=11). The aqueous levels of PEGF/VPF were significantly higher in both groups than in 10 diabetics without such complications. The levels were very high in patients with neovascular glaucoma, suggesting that VEGF/VPF is involved in the pathogenesis and progression of diabetic neovascular glaucoma. The serum levels were not significantly related to the presence or the stage of retinopathy. The findings suggest the possibility of treatment of neovascular glaucoma using anti-VRGF/VFP preparations.

Scopus

PubMed

researchmap

Vascular endothelial growth factor (VEGF) enhances glucose transport in retinal endothelial cells through upregulation of GLUT1 glucose transporter

Hirohito Sone

Diabetes 1998

Change in the expression of vascular endothelial growth factor (VEGF) by swimming

Hirohito Sone

Diabetes 1998

Evaluation of α<sub>1</sub>-adrenoceptor antagonist and antioxidant therapy on diabetes-induced changes in retinal NAD(P)-redox status:: Evidence against "pseudohypoxia?"

Hirohito Sone

Diabetes 1998

Non-invasive ultrasonic analysis of femoral artery wall in patients with NIDDM: Evaluation of early arteriosclerotic lesions and relationship between diabetic neuropathy

Hirohito Sone

Diabetes 1997

Effects of pancreatic hormones and vasoactivators on vascular endothelial growth factor production of human vascular smooth muscle cells

Hirohito Sone

Diabetes 1997

Modulation of vascular endothelial growth factor (VEGF) in animal models of diabetic retinopathy: Future implications

Hirohito Sone

Diabetes 1997

Acute glucose deprivation and progesterone induce vascular endothelial growth factor on retinal pigment epithelial cells

Hirohito Sone

Diabetes 1996

Non-invasive evaluation of lower limb circulation in non-insulin dependent diabetic patients

Hirohito Sone

Diabetes 1996

Radioiodinated metaiodo-benzylguanidine scintigraphy for pheochromocytoma Reviewed

Hirohito Sone, Yukichi Okuda, Yasushi Nakamura, Nobuyoshi Ishikawa, Takashi Yamaoka, Yasushi Kawakami, Masato Odawara, Teruhiko Matsushima, Koichi Kawai, Kamejiro Yamashita

Hormone Research in Paediatrics 46 ( 3 ) 138 - 142 1996

Language：English Publishing type：Research paper (scientific journal)

Radioiodinated metaiodobenzylguanidine (MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. We describe herein the first case of a definite adrenocortical adenoma that demonstrated false-positive uptake on MIBG scintigraphy. In addition, we reviewed all 13 reported cases showing false-positive uptake, and suggest that careful evaluation is needed before diagnosing a ‘silent’ or ‘asymptomatic’ pheochromocytoma. © 1996 S. Karger AG, Basel.

DOI： 10.1159/000185010

Scopus

PubMed

researchmap

Study of vegf/vpf levels in diabetic proliferative retinopathy and nephropathy

Hirohito Sone

Diabetes 1995

Transient nephrogenic diabetes insipidus accompanied by possible psychogenic polydipsia Reviewed

Hirohito Sone, Koichi Kawai, Masaaki Nishi, Shuya Shimakura, Chieko Bannai, Yasushi Kawakami, Masato Odawara, Teruhiko Matsushima, Yukichi Okuda, Kamejiro Yamashita

Hormone Research in Paediatrics 44 ( 4 ) 193 - 196 1995

Language：English Publishing type：Research paper (scientific journal)

A 50-year-old Japanese man had been suffering from polydipsia and polyuria for 2 months without any other specific symptoms. His daily urinary output reached 5 liters. On admission, no abnormalities of the kidneys, heart, thyroid, adrenals, pituitary or hypothalamus were detected by laboratory tests and MRI of the head. Pure psychogenic polydipsia was ruled out because his urine volume did not decrease sufficiently with 18 h of water deprivation and the subsequent injection of aqueous vasopressin. Plasma arginine vasopressin (AVP) levels against plasma osmolality remained within the normal range during the test. These results indicated that diabetes insipidus in this case was caused by renal insensitivity to AVP. The symptoms disappeared spontaneously, and marked improvement was observed in a second water deprivation test 1 month later, although the maximum urine concentration was still subnormal. The combination of both latent insufficiency of AVP secretion and impairment of the renal countercurrent system induced by psychogenic polydipsia was speculated as a possible mechanism for the transient nephrogenic diabetes insipidus in this case. © 1995 S. Karger AG, Basel.

DOI： 10.1159/000184624

Scopus

PubMed

researchmap

Effect of tzp-4238 on bone-mineral content and strength of osteoporotic rats

Hirohito Sone

Calcified Tissue International 1994

A case of diabetic neuropathy treated with selective thrombin inhibitor (argatroban)

Y. Tsurushima, Y. Okuda, S. Suzuki, Y. Asakura, K. Tada, M. Mizutani, M. Ogawa, H. Sone, M. Asano, C. Bannai, Y. Kawakami, M. Odawara, T. Matsushima, K. Kawai, K. Yamashita

Therapeutic Research 15 ( 12 ) 535 - 538 1994

Language：Japanese Publishing type：Research paper (international conference proceedings)

A 71 year-old male diabetic patient with diabetic neuropathy was treated with selective thrombin inhibitor (argatroban) for 40 days. This agent improved his sensory disturbance, including dysesthesia and coldness in both lower extremities. As rheological parameter, thrombin-antithrombin III complex (TAT complex) decreased from 3.8 to 1.9 ng/ml, the microcirculation of lower extremities might be improved. Thus, it is suggested that this selective thrombin inhibitor (argatroban) is an useful agent in the treatment of diabetic neuropathy.

Scopus

researchmap

　 PREV - NEXT 　

<SONE, Hirohito>

Papers - SONE, Hirohito