Faculty Profiles - SONE, Hirohito

Papers - SONE, Hirohito

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糖尿病の寛解が心血管疾患の発症に及ぼす影響

島山千弥, 藤原和哉, 大江桃子, 上神洋平, 滝澤大輝, 佐藤隆明, 鈴木浩史, 北澤勝, 松林泰弘, 山田貴穂, 曽根博仁

日本動脈硬化学会総会プログラム・抄録集 57回 236 - 236 2025.6

Estimation of the Effects and Costs of Lifestyle Intervention and Treatment With Voglibose in the Japanese Prediabetic Population: A Cost-Effectiveness Analysis. International journal

Mio Ezura, Shota Saito, Masahiro Ishizawa, Kazuya Fujihara, Hirohito Sone, Kohei Akazawa

Value in health regional issues 47 101098 - 101098 2025.5

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVES: Prediabetes is a condition in which blood glucose levels are higher than normal but not high enough for a type 2 diabetes (T2DM) diagnosis. Lifestyle and pharmacological interventions, such as voglibose, an alpha-glucosidase inhibitor that reduces postprandial hyperglycemia, can address pathophysiological deficits in prediabetes. In Japan, voglibose is approved for preventing T2DM in patients with impaired glucose tolerance. We evaluated the cost-effectiveness of a lifestyle intervention alone and a combined intervention (lifestyle + voglibose) in extending quality-adjusted diabetes-free life years (QADFLY) and the associated costs in the Japanese prediabetic population. METHODS: We developed a Markov microsimulation model to replicate the natural history of a theoretical cohort of the Japanese prediabetic population. Transition probabilities were derived from the results of current clinical practices regarding prediabetes. Health outcomes were measured in the number of QADFLYs gained. Model robustness was addressed through one-way sensitivity analysis. The costs and QADFLYs were discounted at a rate of 2% per year. RESULTS: In the base case, the lifestyle intervention cost $4969 with 3.976 QADFLYs, compared with $5407 and 4.274 QADFLYs for the combined intervention. Prediabetic individuals in Japan would spend an additional $1469 to gain one more QADFLY when voglibose is added to lifestyle intervention. CONCLUSIONS: The combined intervention is cost-effective, leading to more patients achieving normal glucose tolerance and fewer progressing to T2DM compared with lifestyle changes alone. In the Japanese prediabetic population, combining lifestyle changes with voglibose should be considered an effective strategy for preventing T2DM.

DOI： 10.1016/j.vhri.2025.101098

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Evans症候群を合併したNodal T follicular helper cell lymphoma NOS(nTFHL-NOS)の一例

福田正穂, 片桐隆幸, 藤野千秋, 川上絢子, 水戸部正樹, 土田拓睦, 米沢穂高, 諏訪部達也, 布施香子, 柴崎康彦, 増子正義, 曽根博仁, 三好寛明, 大島孝一, 瀧澤淳

日本リンパ腫学会会誌 65 127 - 127 2025.5

NelarabineとMTX髄注による脊髄後索障害を認めたETP-ALLの1例

藤野千秋, 片桐隆幸, 武田ルイ, 川上絢子, 米沢穂高, 諏訪部達也, 柴崎康彦, 布施香子, 瀧澤淳, 曽根博仁, 増子正義, 山岸拓磨

臨床血液 66 ( 5 ) 381 - 381 2025.5

閉眼片足立ち時間による糖尿病及びその併存症の発症予測

佐藤隆明, 藤原和哉, 矢口雄大, 山本正彦, 北澤勝, 鈴木浩史, 松林泰弘, 石黒創, 大澤妙子, 山田貴穂, 加藤公則, 曽根博仁

糖尿病 68 ( Suppl. ) S - 215 2025.4

脂肪肝の程度に応じた,SGLT2阻害薬及びDPP4阻害薬の血糖コントロール及び脂肪肝の改善度の比較 NISM-Study post-hoc解析

北澤勝, 武田安永, 堀川千嘉, 佐藤隆明, 大澤妙子, 石澤正博, 鈴木浩史, 松林泰弘, 藤原和哉, 山田貴穂, 曽根博仁

糖尿病 68 ( Suppl. ) S - 231 2025.4

Demographic and Dietary Determinants of the Association between Dietary Fiber Intake and Obesity in Japanese Adults with Type 2 Diabetes: A Cross-Sectional Study (JDDM 78). International journal

Efrem d'Ávila Ferreira, Mariko Hatta, Laymon Khin, Izumi Ikeda, Mizuki Takeuchi, Yasunaga Takeda, Sakiko Yoshizawa Morikawa, Chika Horikawa, Noriko Kato, Hiroshi Maegawa, Kazuya Fujihara, Hirohito Sone

Public health nutrition 1 - 20 2025.2

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: To evaluate the association between dietary fiber intake and obesity in Japanese outpatients with type 2 diabetes, as well as the demographic and dietary factors influencing this association. DESIGN: Cross-sectional study with nationwide registry data on Japanese type 2 diabetes outpatients (2014-2019). Diet was self-reported via a Food Frequency Questionnaire. Obesity was defined as BMI ≥25 kg/m2. SETTING: Clinics throughout Japan. PARTICIPANTS: 1,565 Japanese outpatients with type 2 diabetes (63.1% men; age range 30-89 years). RESULTS: Multivariate analysis revealed that a higher dietary fiber intake was associated with a lower risk of obesity in all participants (95% CI = 0.439-0.795, p < 0.001). Stratified analysis showed a significant inverse association between fiber intake and obesity in men and the older age groups (59-89 years), but not in women or the younger age group (30-58 years). In men, higher fiber intake was associated with healthier lifestyle behaviors, including increased physical activity (p < 0.001) and non-smoking (p < 0.001), with stronger associations compared to women. Vegetables, fruits, and soybeans/soy products were strongly correlated with fiber, while grains had a weak correlation. Folate was the micronutrient most strongly correlated with fiber. CONCLUSION: Higher fiber intake was associated with lower obesity risk, particularly in men and older age groups. These findings emphasize the need for targeted public health initiatives promoting the intake of diverse fiber-rich foods to effectively manage obesity. Further research is needed to understand sex- and age-specific factors in the fiber-obesity relationship in diverse populations.

DOI： 10.1017/S136898002500014X

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Positive association of large alcohol intake per occasion with vision-threatening severe diabetic retinopathy or diabetic macular edema in Japanese men with type 2 diabetes. International journal

Masahiko Yamamoto, Kazuya Fujihara, Hiruma Hasebe, Yuta Yaguchi, Takaho Yamada, Satoru Kodama, Shiro Tanaka, Hirohito Sone

Preventive medicine 191 108220 - 108220 2025.2

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: Differing from the overall consumption of alcohol, whether consuming large quantities of alcohol per drinking occasion is associated with higher risk of developing severe diabetic retinopathy remains unknown. METHODS: We examined whether the quantity per drinking occasion (QPO), including a large QPO, and the combinations of the frequency of alcohol consumption (FAC) and QPO were associated with higher risk of developing severe diabetic retinopathy or diabetic macular edema (DME) using adjusted Cox models. Severe diabetic retinopathy or DME was designated as a vision-threatening treatment-required diabetic eye disease (TRDED). For each man with type 2 diabetes who participated in this longitudinal retrospective cohort study, the date of the earliest health check-up during the inclusion period (April 2008 to August 2016) was set as the start date of follow-up. RESULTS: A TRDED was observed in 425 of 21,392 Japanese men aged 22-74 years with type 2 diabetes during a mean follow-up of 4.3 years (4.6/1000 person-years). Multivariable Cox analysis showed that a large QPO, defined as drinking three drinks or more per occasion, in low- (hazard ratio [HR], 4.76; 95 % CI, 2.06-10.97), intermediate- (HR, 1.58; 95 %CI, 1.001-2.50), and high-frequency categories (HR, 2.01; 95 % CI, 1.20-3.36) was significantly associated with elevated risks of TRDED. CONCLUSIONS: In addition to the total amount of ethanol, these findings imply the necessity of avoiding the consumption of large amounts of alcohol on a single occasion to prevent severe diabetic retinopathy or DME.

DOI： 10.1016/j.ypmed.2025.108220

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妊娠糖尿病合併妊婦の産後早期糖代謝異常を予測する因子の検討

山田貴穂, 柳生田紀子, 菅井駿也, 宗田聡, 倉林工, 児玉暁, 吉原弘祐, 西島浩二, 曽根博仁

新潟医学会雑誌 139 ( 2 ) 65 - 66 2025.2

Cross-sectional and Longitudinal Associations Between Family History of Type 2 Diabetes Mellitus, Hypertension, and Dyslipidemia and Their Prevalence and Incidence: Toranomon Hospital Health Management Center Study (TOPICS24). International journal

Izumi Ikeda, Risa Igarashi, Kazuya Fujihara, Yasunaga Takeda, Efrem d'Ávila Ferreira, Khin Lay Mon, Satoru Kodama, Yasumichi Mori, Takashi Kadowaki, Ritsuko Honda, Yasuji Arase, Hirohito Sone

Mayo Clinic proceedings 2025.1

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: To examine the association between a positive family history (parents, siblings, and grandparents) of type 2 diabetes mellitus (T2DM), hypertension, and dyslipidemia and their prevalence and incidence in the same population. PATIENTS AND METHODS: Data on 41,361 participants who underwent health examinations between January 1, 1997, and December 31, 2007, were analyzed, and the results of logistic and Cox regression analyses in the same cohort were examined. RESULTS: Cross-sectional analyses showed that the prevalence of all three diseases increased with a positive family history, especially T2DM, with an odds ratio (OR) of 12.00 (95% CI, 7.82 to 18.41) when the number of affected relatives was greater than or equal to 3 with an OR of 20.43 (95% CI, 11.0 to 37.8) for a positive family history across three generations compared with no family history. However, redefining family history from "parents, siblings, and grandparents" to "parents and siblings" or "parents only" did not significantly change ORs for each disease. Among those with a positive family history and body mass index greater than or equal to 30.0 kg/m2 hypertension was 19 times more prevalent compared with no family history and body mass index of 18.5 to 24.9 kg/m2. In the longitudinal study, family history strongly influenced incident T2DM (hazard ratio[HR], 2.40; 95% CI, 1.93 to 2.98), hypertension (HR, 1.43; 95% CI, 1.26 to 1.62), and dyslipidemia (HR, 1.41; 95% CI, 1.08 to 1.83), respectively. CONCLUSION: Obtaining a family history of these diseases was useful in identifying high-risk groups. Also, for T2DM, the influence of a positive family history was strongest with a marked increase in risk with overlap of affected family members, suggesting that a family history is useful for early detection and prevention.

DOI： 10.1016/j.mayocp.2024.10.020

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Impact of diabetes remission or progression on the incidence of cardiovascular disease in Japan: historical cohort study using a nationwide claims database. International journal

Chihiro Shimayama, Kazuya Fujihara, Laymon Khin, Hiroki Takizawa, Chika Horikawa, Takaaki Sato, Masaru Kitazawa, Yasuhiro Matsubayashi, Takaho Yamada, Hirohito Sone

Cardiovascular diabetology 24 ( 1 ) 37 - 37 2025.1

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Previous studies demonstrated that diabetes remission can occur during intensive intervention and in real-world settings. However, the impact of diabetes remission in real-world settings on the incidence of cardiovascular disease (CVD) remains unclear. METHODS: This retrospective cohort study included 299,967 individuals aged 20-72 years who underwent multiple checkups between 2008 and 2020 and completed ≥ 3 years of follow-up. Patients were divided into four groups according to changes in glycated hemoglobin levels and the use of diabetes medications during the 1-year baseline period: diabetes mellitus (DM)+/no remission, DM+/remission, DM-/no progression, and DM-/progression. The risk of CVD was evaluated using multivariable Cox regression analysis. RESULTS: The median follow-up period was 5.0 years. The rates of CVD in the DM+/no remission, DM+/remission, DM-/no progression, and DM-/progression groups were 7.96, 4.76, 1.99, and 5.47 per 1000 person-years, respectively. Compared with DM+/no remission, DM+/remission reduced the risk of CVD [hazard ratio (HR) = 0.71, 95% confidence interval (CI) = 0.57-0.89]. Meanwhile, the HR for CVD in the DM+/remission group was 0.75 (95% CI = 0.56-0.99) for change in BMI ≤ 0%, versus 0.66 (95% CI = 0.45-0.96) for change in BMI > 0%. CONCLUSIONS: In a real-world setting without intensive intervention, diabetes remission decreased the risk of CVD by approximately 30% regardless of changes in BMI, suggesting that diabetes remission can prevent CVD without weight loss in routine care and emphasizing the importance of achieving remission.

DOI： 10.1186/s12933-025-02578-y

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Association of changes in the type 2 diabetes and MASLD/related SLD status with risk of developing cardiovascular disease. International journal

Yasuhiro Matsubayashi, Kazuya Fujihara, Laymon Khin, Efrem d'Àvila Ferreira, Shizuka Takabayashi, Yuko Yamashita, Takaho Yamada, Satoru Kodama, Hirohito Sone

Diabetes, obesity & metabolism 2025.1

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND & AIMS: This study assessed the association of remission of type 2 diabetes mellitus (DM) or metabolic dysfunction-associated steatotic liver disease (MASLD)/related SLD (r-SLD; MASLD with excessive alcohol intake) as defined by the fatty liver index with the risk of cardiovascular disease (CVD). METHODS: Health examination data at baseline and after 2 years (2-Years) were extracted from a nationwide claims database in Japan. Among participants aged 18-72 years with at least 3 years of follow-up, 9345 participants with DM-associated MASLD/r-SLD and 71 932 participants with non-DM MASLD/r-SLD at baseline were included in the study. The participants were stratified by the achievement of remission of MASLD/r-SLD or DM at 2-Years. In each group after stratification, the risk of new-onset CVD during the observation period was analysed using multivariate Cox proportional hazards models. RESULTS: During a median follow-up of 4.9 years (starting from 2-Years), 1368 cases of CVD were observed. The hazard ratio (95% confidence interval) for CVD was 0.50 (0.31-0.80) for participants with remission of DM, 0.65 (0.47-0.91) for participants with remission of MASLD/r-SLD, and 0.34 (0.15-0.77) for participants with remission of both DM and MASLD/r-SLD. Conversely, remission of MASLD/r-SLD was not linked to a reduced risk of CVD in participants with non-DM MASLD/r-SLD. CONCLUSION: The association of MASLD/r-SLD remission with CVD risk differs greatly in the presence and absence of DM. In patients with DM-MASLD/r-SLD, MASLD/r-SLD remission can significantly reduce CVD risk similarly as remission of DM.

DOI： 10.1111/dom.16196

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Dietary potassium intake and its interaction with sodium intake on risk of developing cardiovascular disease in persons with type 2 diabetes: The Japan Diabetes Complication and its Prevention Prospective study (JDCP study 12). International journal

Chika Horikawa, Mitsuyoshi Takahara, Naoto Katakami, Yasunaga Takeda, Mizuki Takeuchi, Kazuya Fujihara, Hiroaki Suzuki, Narihito Yoshioka, Hitoshi Shimano, Jo Satoh, Yasuaki Hayashino, Naoko Tajima, Rimei Nishimura, Yoshimitsu Yamasaki, Hirohito Sone

Diabetes, obesity & metabolism 27 ( 1 ) 394 - 406 2025.1

Language：English Publishing type：Research paper (scientific journal)

AIMS: Many guidelines recommend increases in potassium intake. However, the relationship of dietary potassium intake with incident cardiovascular disease (CVD) has not been examined in those with type 2 diabetes (T2DM), including sodium acting antagonistically with potassium. We investigated these relationships in Japanese patients with T2DM. MATERIALS AND METHODS: The investigation was part of the JDCP study, a nationwide prospective study begun in 2007. Analysed were 1477 persons with T2DM, 40-75 years of age, who completed a brief-type, self-administered Diet History Questionnaire at baseline. Primary outcome was a CVD event during the follow-up median 7 years (3.9-8.1 years). Hazard ratios (HRs) for CVD were estimated by Cox regression adjusted for confounders of daily potassium intake categorized by tertiles. Tertiles of sodium intake were also analysed. RESULTS: Mean daily potassium intake in tertiles was 1877, 2627 and 3532 mg, respectively, and significant associations were not shown between potassium intake and incidence of CVD. When HRs for CVD were stratified for potassium intake in tertiles (reference group, bottom tertile) and sodium intake (reference group, bottom tertile), potassium intake in the bottom tertile and sodium intake in the second and top tertiles were associated with significantly elevated HR for CVD (2.79 [1.02-7.63] and 3.92 [1.30-11.79], respectively). CONCLUSIONS: Low potassium intake in conjunction with high sodium intake was significantly associated with increased incident CVD in persons with T2DM. However, CVD incidence was not related to high potassium intake, regardless of sodium intake.

DOI： 10.1111/dom.16035

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Relationship Between Improvements in Glycemic Control and Risk of Pregnancy Complications in Patients With Diabetes Mellitus: Metaregression Analysis of Randomized Controlled Trials of Intensive Glucose Management

Satoru Kodama, Kazuya Fujihara, Noriko Yagyuda, Yoko Yachi, Chika Horikawa, Yasunaga Takeda, Sakiko Yoshizawa Morikawa, Takaho Yamada, Kiminori Kato, Yoshimi Nakagawa, Shiro Tanaka, Hitoshi Shimano, Hirohito Sone

Journal of Diabetes Research 2025 ( 1 ) 2025.1

Publishing type：Research paper (scientific journal) Publisher：Wiley

Background: It remains unknown whether improvements in prognosis of pregnancy in patients with diabetes mellitus are dependent on glycemic control (GC). This metaregression analysis was aimed at exploring the relationships between the improvements in GC.

Methods: Using Embase and MEDLINE (from Jan. 1, 1950, to Apr. 29, 2024), we searched for randomized controlled trials of intensive glucose management in pregnant women with gestational, pregestational, or overt diabetes mellitus, in which the blood glucose level using any GC indicator and the incidence of any adverse maternal and/or fetal outcome were compared between two groups with different intensities of glucose management. Relative risks (RRs) of individual adverse outcomes were regressed on the reductions in individual GC indicators.

Results: We examined the dose–response relationship between reductions in four GC indicators (hemoglobin A1c (A1C), fasting plasma glucose (FPG), 2‐h postprandial glucose, and mean blood glucose) and 14 adverse pregnancy outcomes in 62 eligible trials. Reductions in FPG were associated with the reduced risk of 10/14 adverse outcomes, with the exceptions being cesarean section, small for gestational age, premature rupture of membranes, and congenital malformation. Reductions in A1C were strongly associated with the reduced risk of cesarean section (r = 0.67, p < 0.001), indicating that the RR (95% confidence interval) for a 1% incremental decrease in A1C was 0.63 (0.49–0.80).

Conclusions: Risk reductions in the majority of pregnancy complications in those with diabetes depend on the improvement of GC induced by intensive glucose management.

DOI： 10.1155/jdr/3490884

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Nutrient Inadequacy Rates Among Japanese Adolescents Aged 10-14: Cross-Sectional Pooled Analysis From 2018 to 2023 (NICE EVIDENCE Study 5). International journal

Efrem d'Avila Ferreira, Sakiko Yoshizawa Morikawa, Yasunaga Takeda, Izumi Ikeda, Risa Igarashi Matsumoto, Mizuki Takeuchi, Mariko Hatta, Chika Horikawa, Laymon Khin, Hajime Ishiguro, Kazuya Fujihara, Yohei Ogawa, Hirohito Sone

Journal of nutrition and metabolism 2025 5568303 - 5568303 2025

Language：English Publishing type：Research paper (scientific journal)

This study aimed to describe the demographics, nutrient and food group intakes, and adherence to dietary guidelines among Japanese adolescents aged 10-14 years. This cross-sectional study involved 5225 elementary and junior high school students who were surveyed for the NICE EVIDENCE project from 2018 to 2023 (mean age: 11.9 ± 1.4 years; 50.3% male). Nutritional intake was assessed using the brief-type self-administered diet history questionnaire (BDHQ). Nutrient intake inadequacy was assessed in four groups (males and females in the 10-11- and 12-14-year age groups) based on the Dietary Reference Intakes for Japanese (2025). Demographic data indicated that the prevalence of thinness was higher among females, while the prevalence of overweight and obesity was higher among males. Overall, daily breakfast consumption was high but tended to decrease with age. Nutritional inadequacy rates were generally higher in females, particularly in the 12-14-year age group. Major micronutrient inadequacies included iron, calcium, magnesium, manganese, phosphorus, potassium, vitamin D, and vitamin B6. Among the nutrients with established dietary goals, salt equivalent intake exceeded 90% inadequacy in all groups, followed by intake inadequacies in dietary fiber, fat energy percentage, and potassium. Confectionery consumption was relatively high in this population (> 50 g/day), indicating a potential area for dietary improvement. Promoting regular breakfast and increasing micronutrients and fiber intakes, while reducing sodium, total fat, and saturated fat intakes, could address nutritional inadequacies in this population.

DOI： 10.1155/jnme/5568303

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バセドウ病とうつ病を治療中に、破壊性甲状腺炎と悪性カタトニア発症し集学的な治療を要した一例

磯貝真理恵, 高澤遥子, 村井幸四郎, 佐藤隆明, 山本正彦, 北澤勝, 鈴木浩史, 松林泰弘, 藤原和哉, 山田貴穂, 小柴みなみ, 吉永清宏, 江川純, 曽根博仁

日本内分泌学会雑誌 100 ( 4 ) 907 - 907 2024.12

Coronary artery disease risk prediction by combined stratification of low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol levels across different glucose statuses. International journal

Junko Yachida, Kazuya Fujihara, Mayuko Harada Yamada, Ayako Kobayashi, Lay Mon Khin, Hiroki Takizawa, Masahiko Yamamoto, Masaru Kitazawa, Yasuhiro Matsubayashi, Takaho Yamada, Satoru Kodama, Hirohito Sone

Diabetes, obesity & metabolism 26 ( 12 ) 5845 - 5856 2024.12

Language：English Publishing type：Research paper (scientific journal)

AIM: To investigate the association between low-density lipoprotein-cholesterol (LDL-C) levels and coronary artery disease (CAD) incidence based on combining high-density lipoprotein-cholesterol (HDL-C) levels and glucose status. MATERIALS AND METHODS: In this retrospective cohort study, we used data from a nationwide claims database (1,524,289 individuals without a history of CAD or familial hypercholesterolaemia; 2008-2019). Cox proportional hazards modelling identified the risk of incident CAD by a novel combination of four HDL-C levels, seven LDL-C levels and glucose status. RESULTS: During the follow-up period (mean: 5.5 years), 8301 (0.99/1000 person-years) events occurred. The risk of CAD increased from lower LDL-C levels accompanied by lower HDL-C levels regardless of the glucose status. Using the most favourable levels of HDL-C and LDL-C (i.e. 60-99 mg/dL and <80 mg/dL, respectively) as references, the hazard ratios (95% confidence interval) for the group with HDL-C levels <40 mg/dL and LDL-C levels <80 mg/dL were 2.74 (1.47-5.11), 2.52 (1.30-4.91) and 2.85 (1.68-4.84) for normoglycaemia, borderline glycaemia and diabetes, respectively. Comparison of the most favourable levels of HDL-C and LDL-C with their least favourable levels (i.e. <40 mg/dL and 180-199 mg/dL, respectively) revealed that the risk of new-onset CAD exhibited a 19-, nine- and seven-fold increase in individuals with normoglycaemia, borderline glycaemia and diabetes, respectively. CONCLUSIONS: To prevent CAD, LDL-C levels should be strictly controlled in patients with low HDL-C levels regardless of glucose tolerance. Individualized treatment, which involves setting target LDL-C levels based on glucose tolerance and HDL-C values, is required.

DOI： 10.1111/dom.15956

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糖尿病モデルマウスにおけるトリュフ抽出物の血糖上昇抑制作用の検討

岩浅啓矢, 鈴木浩史, 石黒創, 渡辺賢一, 郭安韜, 小西徹也, 井口晃徳, 中川沙織, 曽根博仁

機能性食品と薬理栄養 18 ( 3 ) 201 - 201 2024.12

Achieving normoglycaemia with tirzepatide: Post hoc exploratory analysis of the SURPASS J‐mono and J‐combo studies

Kazuya Fujihara, Yasuhiro Matsubayashi, Masaru Kitazawa, Takaaki Sato, Masakazu Takeuchi, Tomonori Oura, Hirohito Sone

Diabetes, Obesity and Metabolism 2024.11

Machine learning algorithms mimicking specialists decision making on initial treatment for people with type 2 diabetes mellitus in Japan diabetes data management study (JDDM76)

Jenny Elizabeth Price, Kazuya Fujihara, Satoru Kodama, Katsuya Yamazaki, Hiroshi Maegawa, Tatsuya Yamazaki, Hirohito Sone

Diabetes & Metabolic Syndrome: Clinical Research & Reviews 2024.11

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Papers - SONE, Hirohito