研究者詳細 - 寺井　崇二

論文 - 寺井　崇二

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フレイルとサルコペニアについて進行消化器癌における体組成と予後との関連

川合弘一, 小林隆昌, 中野応央樹, 五十嵐聡, 河久順志, 阿部聡司, 上村博輝, 坂牧僚, 林和直, 上村顕也, 土屋淳紀, 高村昌昭, 寺井崇二

新潟医学会雑誌 132 ( 10 ) 350 - 352 2018年10月

超音波内視鏡における音速補正モードの有用性

林和直, 五十嵐聡, 河久順志, 高橋一也, 冨永顕太郎, 水野研一, 橋本哲, 横山純二, 山際訓, 寺井崇二

Gastroenterological Endoscopy 60 ( Suppl.2 ) 2110 - 2110 2018年10月

ステロイド使用例における胆管結石治療の現状

五十嵐聡, 林和直, 河久順志, 冨永顕太郎, 高橋一也, 水野研一, 橋本哲, 横山純二, 山際訓, 寺井崇二

Gastroenterological Endoscopy 60 ( Suppl.2 ) 2086 - 2086 2018年10月

重篤な基礎疾患を持たないサイトメガロウイルス小腸炎の特徴と小腸内視鏡の有用性

横山純二, 冨永顕太郎, 寺井崇二

日本消化器病学会雑誌 115 ( 臨増大会 ) A760 - A760 2018年10月

炎症性腸疾患患者における血清IgAの検討

冨永顕太郎, 横山純二, 寺井崇二

Gastroenterological Endoscopy 60 ( Suppl.2 ) 2121 - 2121 2018年10月

NASHモデルマウスにおける自律神経系を介した消化管ホルモンの関与

名古屋拓郎, 上村顕也, 井上良介, 酒井規裕, 後藤諒, 高昌良, 丹羽佑輔, 坂牧僚, 中村由香, 上野将紀, 寺井崇二

日本消化器病学会雑誌 115 ( 臨増大会 ) A732 - A732 2018年10月

Peroral cholangioscopy of nivolumab-related (induced) ulcerative cholangitis in a patient with non-small cell lung cancer 査読

Kuraoka, N., Hara, K., Terai, S., Yatabe, Y., Horio, Y.

Endoscopy 50 ( 9 ) E259 - E261 2018年9月

Listeria meningitis during infliximab-based treatment for ulcerative colitis 査読

Tsuchiya, A., Terai, S.

Internal Medicine 57 ( 17 ) 2603 - 2603 2018年9月

Disappearance of multiple pancreatic cysts after prednisolone treatment in a patient with autoimmune pancreatitis 査読

Kohisa, J., Tsuchiya, A., Ikemi, M., Terai, S.

Clinical Case Reports 6 ( 9 ) 1898 - 1900 2018年9月

マウス肝線維化進展予防薬の探索及び効果の検証

酒井規裕, 上村顕也, 後藤諒, 小川光平, 坂牧僚, 阿部聡司, 榎本初音, 立木秀尚, 寺井崇二

肝臓 59 ( Suppl.2 ) A723 - A723 2018年9月

消化管疾患と肝疾患の関連-消化管・肝臓間の相互の影響- 自律神経線維による肝,脳,腸の臓器間ネットワークを介した肝切除後の肝再生メカニズムの検討

上村顕也, 寺井崇二

肝臓 59 ( Suppl.2 ) A609 - A609 2018年9月

Diagnosis and management of fibromuscular dysplasia and segmental arterial mediolysis in gastroenterology field: A mini-review. 査読国際誌

Ko M, Kamimura K, Ogawa K, Tominaga K, Sakamaki A, Kamimura H, Abe S, Mizuno K, Terai S

World journal of gastroenterology 24 ( 32 ) 3637 - 3649 2018年8月

Gastric Cavernous Hemangioma Resected by Endoscopic Submucosal Dissection. 査読

Watanabe Y, Takahashi K, Yokoyama J, Terai S

Internal medicine (Tokyo, Japan) 57 ( 15 ) 2269 - 2270 2018年8月

The Value of <sup>18</sup>F-FDG PET in the Diagnosis of Intertrabecular Vertebral Metastasis in a Small Cell Lung Cancer Patient with a High Serum CEA Level. 査読

Morita S, Suda T, Oda C, Kobayashi M, Hoshi T, Kanefuji T, Yagi K, Hasegawa G, Terai S

Internal medicine (Tokyo, Japan) 58 ( 3 ) 415 - 418 2018年8月

Successful treatment of aortic dissection during sorafenib therapy for hepatocellular carcinoma. 査読国際誌

Tsuchiya A, Ogawa M, Watanabe Y, Kimura N, Hayashi K, Suda T, Terai S

Clinical case reports 6 ( 8 ) 1643 - 1644 2018年8月

Potential role of extracellular vesicle-mediated antigen presentation in Helicobacter pylori hypersensitivity during eradication therapy. 査読国際誌

Takamasa Ito, Takashi Shiromizu, Shunsuke Ohnishi, Shotaro Suzuki, Katsuhiro Mabe, Akito Hasegawa, Hideyuki Ujiie, Yasuyuki Fujita, Yuichi Sato, Shuji Terai, Mototsugu Kato, Masahiro Asaka, Takeshi Tomonaga, Hiroshi Shimizu, Riichiro Abe

The Journal of allergy and clinical immunology 142 ( 2 ) 672 - 676 2018年8月

Rapidly declining skeletal muscle mass predicts poor prognosis of hepatocellular carcinoma treated with transcatheter intra-arterial therapies. 査読国際誌

Takamasa Kobayashi, Hirokazu Kawai, Oki Nakano, Satoshi Abe, Hiroteru Kamimura, Akira Sakamaki, Kenya Kamimura, Atsunori Tsuchiya, Masaaki Takamura, Satoshi Yamagiwa, Shuji Terai

BMC cancer 18 ( 1 ) 756 - 756 2018年7月

記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND: The impact of sarcopenia on the prognosis of patients with hepatocellular carcinoma (HCC) who receive transcatheter intra-arterial therapies, including transcatheter arterial chemoembolization and transcatheter arterial infusion chemotherapy, remains unclear. We investigated the prognostic value of skeletal muscle loss (SML) stratified by cutoffs for sarcopenia and rate of change in skeletal muscle mass over 6 months. METHODS: We retrospectively evaluated 102 patients with HCC treated with transcatheter intra-arterial therapies between 2005 and 2015. Computed tomography images of the third lumbar vertebra (L3) were analyzed to obtain the skeletal muscle area normalized for the height squared, defined as the skeletal muscle index at L3 (L3 SMI), before and 6 months after treatment. Low or high SMI was defined using cutoff values of 42 cm2/m2 in men and 38 cm2/m2 in women. The rate of change in skeletal muscle mass (ΔL3 SMI) over 6 months was calculated. Overall survival (OS) was compared in groups classified by baseline L3 SMI and ΔL3 SMI; prognostic significance was assessed with univariate and multivariate analyses, using Cox proportional hazards models. RESULTS: OS did not differ significantly between groups with low (n = 31) and high (n = 71) SMI at baseline (P = 0.172), but OS was significantly poorer in patients with SML (n = 41), defined as ΔL3 SMI < - 4.6% over 6 months than in those without SML (n = 61, P = 0.018). On multivariate analysis, SML (hazard ratio [HR], 1.675; 95% confidence interval [CI], 1.031-2.721; P = 0.037), serum alpha-fetoprotein ≥20 ng/mL (HR, 2.550; 95% CI, 1.440-4.515; P = 0.001), and maximum tumor diameter ≥ 30 mm (HR, 1.925; 95% CI, 1.166-3.179; P = 0.010) were independent predictors of poor OS. Baseline L3 SMI was not significantly associated with OS (HR, 1.405; 95% CI, 0.861-2.293; P = 0.174). CONCLUSIONS: ΔL3 SMI was an independent prognostic factor in patients with HCC treated with transcatheter intra-arterial therapies. Further study is required to reveal whether prevention of skeletal muscle depletion might be a new therapeutic strategy to contribute to improved clinical outcomes in patients with HCC.

DOI： 10.1186/s12885-018-4673-2

PubMed

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Management decision based on lymphovascular involvement leads to favorable outcomes after endoscopic treatment of esophageal squamous cell carcinoma 査読

Kazuya Takahashi, Satoru Hashimoto, Ken-Ichi Mizuno, Takamasa Kobayashi, Kentaro Tominaga, Hiroki Sato, Junji Kohisa, Satoshi Ikarashi, Kazunao Hayashi, Manabu Takeuchi, Junji Yokoyama, Hirokazu Kawai, Yuichi Sato, Masaaki Kobayashi, Shuji Terai

Endoscopy 50 ( 7 ) 662 - 670 2018年7月

A case of inferior vena cava thrombosis caused by compression due to growing giant liver cyst. 査読

Kimura N, Tsuchiya A, Ogawa M, Watanabe Y, Hayashi K, Yokoyama J, Umezu H, Terai S

Clinical journal of gastroenterology 12 ( 1 ) 71 - 75 2018年7月

Anti-Programmed Cell Death-1 Immunotherapy-Related Secondary Sclerosing Cholangitis. 査読国際誌

Ogawa K, Kamimura K, Terai S

Hepatology (Baltimore, Md.) 69 ( 2 ) 914 - 916 2018年7月

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